{"title":"Clinical diagnosis and treatment of G2 laryngeal neuroendocrine tumors.","authors":"Zhen Xu, Xiuyun Wu, Yanjiao Hu, Ce Wu, Xin Wang, Xiaojuan Zhang, Yong Zhang, Yichuan Huang","doi":"10.1080/00016489.2024.2437017","DOIUrl":"https://doi.org/10.1080/00016489.2024.2437017","url":null,"abstract":"<p><strong>Background: </strong>Neuroendocrine tumors are rare malignancies of the head and neck, especially in the larynx. Variations in the location and morphology of laryngeal neuroendocrine tumors result in a lack of standardized clinical treatment.</p><p><strong>Objective: </strong>This study aimed to examine the treatment and prognosis of laryngeal neuroendocrine tumors in the G2 stage.</p><p><strong>Material and methods: </strong>Data from eight patients diagnosed with G2 stage laryngeal neuroendocrine tumors, this collection of common clinical cases was analyzed retrospectively to examine the disease's clinical characteristics, treatment, and prognosis affecting the larynx.</p><p><strong>Results: </strong>Seven cases were supraglottic type and one was a glottic type. These cases were treated with open surgery and CO<sub>2</sub> laser resection with support laryngoscopy, respectively. After surgery, six patients survived, one passed away due to pulmonary metastasis, and one case was lost to follow-up. OS and DSF rates at 1, 3, 5 years were 87.50%, 65.63% and 65.60%, respectively.</p><p><strong>Conclusion and significance: </strong>The clinical manifestations of G2 stage laryngeal neuroendocrine tumors varied across different locations. Surgical resection of the lesion is the standard treatment. Selection between open neck surgery and support laryngoscope CO<sub>2</sub> laser surgery depends on the tumor's size and location. Following radical surgery, the tumor demonstrates a favorable prognosis.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia Crescio, Sebastiana Lai, Alessandra Manca, Angelo Deiana, Michele Angelo Bella, Andrea Tondo, Laila El Bachiri, Simona Varrucciu, Davide Rizzo, Jacopo Galli, Antonio Cossu, Francesco Bussu
{"title":"Ultrasound guided procedures in the head and neck: a clinician centered model.","authors":"Claudia Crescio, Sebastiana Lai, Alessandra Manca, Angelo Deiana, Michele Angelo Bella, Andrea Tondo, Laila El Bachiri, Simona Varrucciu, Davide Rizzo, Jacopo Galli, Antonio Cossu, Francesco Bussu","doi":"10.1080/00016489.2025.2449829","DOIUrl":"https://doi.org/10.1080/00016489.2025.2449829","url":null,"abstract":"<p><strong>Background: </strong>US guided sampling is a validated diagnostic approach for non-thyroid deep head and neck masses.</p><p><strong>Aim: </strong>To describe the setting of a clinician-driven Lump Clinic and analyze a monoinstitutional 7-year database of 849 patients undergoing US-guided sampling.</p><p><strong>Methods: </strong>FNA with Rapid OnSite Evalutation (ROSE) was the first diagnostic step. In the last years in selected cases, upon ROSE and discussion between clinician and histopathologist, a core biopsy was performed, usually in the same access. If cytology is non-diagnostic, and core biopsy have not been obtained, all available clinical and diagnostic data were re-examined by surgeons and cytopathologists to establish a multiparametric diagnosis (MD).</p><p><strong>Results: </strong>Cytology and MD showed a sensitivity of 91.8% and 95.3% respectively and a specificity of 95.7% in diagnosing malignancy. Complication rate of US guided sampling was 0,12% (considering the number of patients: 1/849), without any serious adverse event.</p><p><strong>Conclusions and significance: </strong>Present data confirm the great safety and utility of US guided procedures in the management of head and neck non-thryoid deep masses, while demonstrating the added value of a lump clinic built on the close cooperation between the head and neck surgeon and the histopathologists.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelsey A Duckett, Mohamed Faisal Kassir, Christopher C Munhall, Kara C Schvartz-Leyzac, Shaun A Nguyen, Robert F Labadie
{"title":"Does cochlear implant electrode array design affect audiologic outcomes? A systematic review and meta-analysis.","authors":"Kelsey A Duckett, Mohamed Faisal Kassir, Christopher C Munhall, Kara C Schvartz-Leyzac, Shaun A Nguyen, Robert F Labadie","doi":"10.1080/00016489.2025.2451074","DOIUrl":"https://doi.org/10.1080/00016489.2025.2451074","url":null,"abstract":"<p><strong>Background: </strong>There is conflicting literature regarding whether cochlear implants (CI) electrode array (EA) selection impacts audiologic outcomes.</p><p><strong>Objective: </strong>To compare outcomes for the two EA designs, precurved and straight.</p><p><strong>Methods: </strong>A systematic search of CINAHL, Cochrane Library, PubMed, and SCOPUS was conducted according to PRISMA guidelines. Included studies reported word recognition scores, sentence recognition scores in quiet or noise, or hearing preservation (HP) rates for patients with post-lingual hearing loss who underwent CI with either EA type. Primary outcome measures included mean difference (baseline vs. post-surgery) and proportions (%) with 95% confidence intervals (CI).</p><p><strong>Results: </strong>Of 4134 unique abstracts screened, 92 studies (<i>N</i> = 5365 patients, 5658 ears) were included. Mean improvement of overall word recognition scores for patients with precurved EAs (46.5%, 95% CI: 43.13-49.88%) was significantly (<i>p</i> = 0.0009) superior to that of patients with straight EAs (36.33%; 95% CI, 31.4-41.27%). There was no significant difference between mean improvement of Azbio Quiet scores, mean improvement of overall sentences in noise scores, or HP or pure-tone averages between patients with precurved EAs and those with straight EAs.</p><p><strong>Conclusions: </strong>Precurved EAs were superior in mean word recognition score improvement, but there was no superior EA design regarding sentence recognition or hearing preservation.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-17"},"PeriodicalIF":1.2,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Das K Nidhin, Amit Keshri, Ravisankar Manogaran, Nazrin Hameed, Prabhakar Mishra, Mohd Aqib, Kalyan Chidambaram, Mohit Sinha
{"title":"Leveraging eCAP thresholds in a logistic model to predict speech outcomes after implantation in anomalous cochlea.","authors":"Das K Nidhin, Amit Keshri, Ravisankar Manogaran, Nazrin Hameed, Prabhakar Mishra, Mohd Aqib, Kalyan Chidambaram, Mohit Sinha","doi":"10.1080/00016489.2024.2449251","DOIUrl":"https://doi.org/10.1080/00016489.2024.2449251","url":null,"abstract":"<p><strong>Background: </strong>Pediatric cochlear implant (CI) recipients with cochlear malformations face challenges due to variable speech recognition outcomes.</p><p><strong>Aims/objectives: </strong>This study assesses the predictive value of intraoperative electrically evoked compound action potential (eCAP) thresholds, residual hearing, age at implantation, Intelligent Quotient (IQ), and malformation type for speech recognition outcomes.</p><p><strong>Material and methods: </strong>A prospective cohort of 52 children (aged 1-4 years) with cochlear malformations who underwent CI between 2016 and 2024 was analyzed. Intraoperative eCAP thresholds were recorded, and disyllable word recognition scores (WRS) were evaluated 24 months postoperatively.</p><p><strong>Results: </strong>Patients included incomplete partition (IP-II, 46.2%), cochlear hypoplasia (30.8%), IP-I (13.5%), and common cavity (9.6%). IP-II cases had higher mean eCAP thresholds (18.85 µV) compared to cochlear hypoplasia and common cavity cases. Higher eCAP thresholds correlated with better WRS outcomes (<i>p</i> < 0.001). Logistic regression revealed eCAP thresholds, residual hearing, age, IQ, and malformation type as significant predictors, with an AUC of 0.92.</p><p><strong>Conclusions and significance: </strong>Intraoperative eCAP thresholds and residual hearing strongly predict auditory outcomes in children with cochlear malformations. Tailored CI strategies based on individual profiles can optimize speech recognition outcomes.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte Benoit, Charlotte Hautefort, Benjamin Verillaud, Philippe Herman, Romain Kania
{"title":"Transmastoid superior semicircular canal dehiscence plugging: VHIT findings.","authors":"Charlotte Benoit, Charlotte Hautefort, Benjamin Verillaud, Philippe Herman, Romain Kania","doi":"10.1080/00016489.2025.2449593","DOIUrl":"https://doi.org/10.1080/00016489.2025.2449593","url":null,"abstract":"<p><strong>Background: </strong>Superior canal dehiscence syndrome (Minor's syndrome) is a condition characterized by a bony defect in the superior semicircular canal (SSCC), with treatment primarily being surgical, notably through plugging of SSCC.</p><p><strong>Aims/objectives: </strong>To examine the clinical outcome and postoperative VHIT findings after transmastoid plugging of the SSCC.</p><p><strong>Materials and methods: </strong>Patients having a superior semicircular canal dehiscence (SSCCD) syndrome with debilitating symptoms who underwent a plugging of the SSCC <i>via</i> a transmastoid approach were included. Through a retrospective chart review and literature review, postop video head impulse test (VHIT) findings, pre and post-operative audiological/vestibular symptoms and audiograms were analyzed in a tertiary care university hospital.</p><p><strong>Results: </strong>All patients operated by plugging of the SSCC through a transmastoid approach had a significative post-operative VHIT deficit in the function of the SSCC (range 0.34-0.70, median gain function 0.41, mean gain function 0.46, standard deviation of 0.15, <i>p</i> = 0.0391) Almost all patients had improvement of their preoperative symptoms. No surgical complication was noted. The literature review also highlighted safety and effectiveness of this surgical technique.</p><p><strong>Conclusion and significance: </strong>Post-operative VHIT findings showed an elective deficit of the SSCC function thus confirming the surgical SSCC plugging through a trans mastoid approach.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-4"},"PeriodicalIF":1.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2025-01-01Epub Date: 2024-12-08DOI: 10.1080/00016489.2024.2436088
Paul Zhaobo Liu, Dimitrios Spinos, Amr Allam, Patrick Long, Wai Sum Cho, Neil Fergie
{"title":"C-reactive protein (CRP) and otorrhoea as prognosticate markers for necrotising otitis externa treatment response: based on a retrospective cohort study of 62 patients.","authors":"Paul Zhaobo Liu, Dimitrios Spinos, Amr Allam, Patrick Long, Wai Sum Cho, Neil Fergie","doi":"10.1080/00016489.2024.2436088","DOIUrl":"10.1080/00016489.2024.2436088","url":null,"abstract":"<p><strong>Background: </strong>Recurrence rate of necrotising otitis externa (NOE) after treatment is 15-20%. This is mainly due to a lack of reliable clinical indicator for the resolution of disease.</p><p><strong>Aims: </strong>We aim to assess the predictability of the otalgia, otorrhoea and C-reactive protein (CRP) levels in a large cohort of sixty-two patients for treatment outcome.</p><p><strong>Methods: </strong>Consecutive patients treated for NOE in our Nottingham tertiary ENT referral unit were retrospectively reviewed from January 2017 to June 2020. Diagnoses were made based on clinical findings and imaging. Good response to treatment was defined as those who required treatment of not longer than the standard six weeks of systemic antibiotics.</p><p><strong>Results: </strong>Average age at presentation was 78.4 years. 75.8% of patients were male. 62.9% had diabetes. Ten patients received more than the standard six weeks of systemic antibiotics. Complications from disease progression included cranial nerve neuropathies (14.5%), meningitis (3.2%), and sigmoid sinus thrombosis (3.2%). Two patients had recurrent or persistent NOE and died while on treatment. Delays in normalization of CRP (<i>p</i> = 0.015) and resolution of otorrhoea (<i>p</i> = 0.014) were associated with an increased need for prolonged antibiotic treatment.</p><p><strong>Conclusion: </strong>Normalisation of CRP and resolution of otorrhea can assist in identifying patients who will likely benefit from a prolonged course of systemic antibiotics.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"88-92"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Music perception and its correlation with auditory speech perception in pediatric Mandarin-speaking cochlear implant users.","authors":"Yunyi Lu, Yutong Wu, Dong Zeng, Chi Chen, Panpan Bian, Baicheng Xu","doi":"10.1080/00016489.2024.2437553","DOIUrl":"10.1080/00016489.2024.2437553","url":null,"abstract":"<p><strong>Background: </strong>Cochlear implants (CI) help regain perception of sound for patients with sensorineural hearing loss. The ability to recognize music pitch may be crucial for recognizing and producing speech for Mandarin.</p><p><strong>Aims/objectives: </strong>This study aims to search for possible influencing factors of music perception and correlations between music perception and auditory speech abilities among prelingually deaf pediatric Mandarin-speaking CI users.</p><p><strong>Material and methods: </strong>Music perception of 24 pediatric CI users and 12 normal hearing children was measured using the MuSIC test. Auditory speech perception of the 24 CI users was also measured and analyzed with their music perception results.</p><p><strong>Results: </strong>Pediatric CI users performed worse than normal hearing children in pitch, rhythm and melody discrimination tests (<i>p</i> < .05). Significant difference in pitch and melody discrimination tests between age at implantation <5 and >5 groups was found. There were significant correlations between perception of consonants, tones, and speech in a noisy environment and perception of music pitch and melody.</p><p><strong>Conclusion and significance: </strong>Prelingually deaf pediatric CI users who received implantation before the age of five perform better in music perception tests. Pediatric CI users with better music perception show better auditory speech perception of Mandarin.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"51-58"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142816972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2025-01-01Epub Date: 2024-11-29DOI: 10.1080/00016489.2024.2432504
Kimitaka Kaga, Makiko Kaga, Mitsuko Shindo
{"title":"Auditory agnosia progressing to cortical deafness. Long-term follow up of a one-year-old child to age 37.","authors":"Kimitaka Kaga, Makiko Kaga, Mitsuko Shindo","doi":"10.1080/00016489.2024.2432504","DOIUrl":"10.1080/00016489.2024.2432504","url":null,"abstract":"<p><strong>Background: </strong>There are two types of central auditory disorders due to pathology of the bilateral auditory cortices in adult patients: <i>auditory agnosia</i> with residual hearing; <i>cortical deafness</i> with total hearing loss. However, long-term changes of hearing acuity over physical development time are unknown.</p><p><strong>Objective: </strong>The aim of this case report was to illustrate the pathophysiology of auditory changes in a 1 year-3 months old child who was diagnosed with auditory agnosia as a sequel of herpes encephalitis and later developed cortical deafness during a 36-year follow-up.</p><p><strong>Materials and methods: </strong>Brain MRI, hearing tests, ABR, DPOAE and developmental tests of speech/language were periodically performed.</p><p><strong>Results: </strong>Brain imaging revealed extensive damage in the bilateral auditory cortices. His auditory speech perception was lost and his language development was seriously delayed. His hearing threshold progressively decreased over time from normal at first to profound hearing loss as a teenager. However, at 29 years of age his ABR was normal. He was able to communicate and converse by sign language or writing.</p><p><strong>Conclusions and significance: </strong>Later developing cortical deafness with profound hearing loss could be caused by retrograde degeneration of the auditory radiation overtime to the bilateral medial geniculate bodies.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"30-35"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2025-01-01Epub Date: 2023-11-17DOI: 10.1080/00016489.2023.2277568
Marcos V Goycoolea, Raquel Levy, Pilar Alarcón, Catherine Catenacci, Gloria Ribalta, Byanka Cagnacci, Rosario Garrido, Elisa Varas, José Manuel Zúñiga
{"title":"Did our cochlear implant program make any difference in the lives of our patients? Achievements of 30 patients with long term follow-up averaging 20 years after cochlear implantation.","authors":"Marcos V Goycoolea, Raquel Levy, Pilar Alarcón, Catherine Catenacci, Gloria Ribalta, Byanka Cagnacci, Rosario Garrido, Elisa Varas, José Manuel Zúñiga","doi":"10.1080/00016489.2023.2277568","DOIUrl":"10.1080/00016489.2023.2277568","url":null,"abstract":"<p><strong>Background: </strong>Cochlear implants are standard of care for the patients with sensorineural hearing loss not benefited from hearing aids.</p><p><strong>Aims: </strong>Evaluate qualitatively the impact of cochlear implantation in the long-term.</p><p><strong>Materials-methods: </strong>Thirty middle-class patients with similar patterns of loss and social environment averaging 20 years post-implantation responded to 52 questions that evaluated psychosocial benefits from cochlear implantation.</p><p><strong>Results: </strong>All completed secondary education and 93% had postgraduate studies. Educational and workwise they are at the same level as their hearing counterparts. All use their cochlear implants and would recommend one to people who need it. They attribute their success to the implant, the rehabilitation program, their family, and a stimulating social environment. Despite their success, most experience difficulties relating with others (socially and at work) due to their hearing condition. They manage but work much harder than their hearing peers to achieve the same.</p><p><strong>Conclusions: </strong>We made a difference in the lives of these patients, however, there is more to be done.</p><p><strong>Significance: </strong>Early intervention, rehabilitation, plus family, and stimulating-environment are crucial in children with sensory deficits.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136395714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2025-01-01Epub Date: 2024-12-30DOI: 10.1080/00016489.2024.2437560
Wenting Wang, Yongci Hao, Huimiao Liu, Sai Zhang, Ting Zhang, Shuangmei Yan, Yang Wang, Yilin Lang, Xu Yang, Ping Gu
{"title":"Clinical characteristics and repositioning efficacy analysis of posterior canal-benign paroxysmal positional vertigo-canalolithiasis and vertigo-cupulolithiasis patients.","authors":"Wenting Wang, Yongci Hao, Huimiao Liu, Sai Zhang, Ting Zhang, Shuangmei Yan, Yang Wang, Yilin Lang, Xu Yang, Ping Gu","doi":"10.1080/00016489.2024.2437560","DOIUrl":"https://doi.org/10.1080/00016489.2024.2437560","url":null,"abstract":"<p><strong>Background: </strong>Currently, there is a paucity of research comparing the clinical characteristics and repositioning efficacy between posterior canal-benign paroxysmal positional vertigo-canalolithiasis (PC-BPPV-ca) and posterior canal-benign paroxysmal positional vertigo-cupulolithiasis (PC-BPPV-cu).</p><p><strong>Aims/objectives: </strong>To observe the clinical characteristics and compare the efficacy of repositioning maneuvers between PC-BPPV-ca and PC-BPPV-cu patients.</p><p><strong>Material and methods: </strong>Clinical information of patients was collected. The G-Force BPPV diagnostic apparatus was used to simulate dizziness handicap inventory (DHI) positional test, and the therapeutic effects, DHI, and sentiment indicators of baseline, and 1-week and 1-month treatment were compared.</p><p><strong>Results: </strong>A total of 92 patients were collected, with 46 cases in each group, and PC-BPPV-cu patients were with the longer disease course and have worse sleep quality than that of PC-BPPV-ca patients. Moreover, the PC-BPPV-cu patients had a shorter latency of nystagmus and a greater intensity of nystagmus (<i>p</i> < .05); however, PC-BPPV-ca patients experienced higher proportion of reverse nystagmus. In terms of repositioning efficacy, the PC-BPPV-cu group had poorer initial efficacy compared to the PC-BPPV-ca group (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>PC-BPPV-cu patients exhibit more extended disease duration, diminished sleep quality, and pronounced nystagmus. Additionally, they tend to experience less effective initial repositioning treatments and continue to present with more pronounced residual depressive symptoms.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"145 1","pages":"7-15"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}