Acta Oto-Laryngologica最新文献_第6页

Diagnostic value of arterial spin labeling perfusion MRI in the differentiation of parotid gland tumors: correlation with histopathology. 动脉自旋标记灌注MRI对腮腺肿瘤分化的诊断价值：与组织病理学的相关性。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-09-01 Epub Date: 2026-05-19 DOI: 10.1080/00016489.2026.2667889

Gökberk Alkan, Zeynel Yoloğlu, Barış Büyük Buyuk, Felat Toprak, Tuncay Tunccan, Caner Kılıc

{"title":"Diagnostic value of arterial spin labeling perfusion MRI in the differentiation of parotid gland tumors: correlation with histopathology.","authors":"Gökberk Alkan, Zeynel Yoloğlu, Barış Büyük Buyuk, Felat Toprak, Tuncay Tunccan, Caner Kılıc","doi":"10.1080/00016489.2026.2667889","DOIUrl":"10.1080/00016489.2026.2667889","url":null,"abstract":"Background: Overlapping signal intensities in conventional MRI limit parotid tumor characterization, necessitating advanced techniques like arterial spin labeling (ASL) to assess physiological parameters such as vascularity.Objectives: To evaluate the diagnostic performance of ASL in differentiating parotid gland tumors by quantifying tumor blood flow ASLm (mean) and ASLmax (maximum) and determining optimal cutoff values correlated with histopathological findings.Methods: Forty-seven patients (20 pleomorphic adenomas [PA], 20 Warthin tumors [WT], 7 malignant) underwent standardized 1.5 T MRI protocols and ASL prior to parotidectomy. Quantitative ASL values were obtained from lesions and contralateral tissue. Statistical comparisons and ROC analyses were performed to identify diagnostic cutoff values.Results: ASLm and ASLmax values were higher in WT compared to PA (p < 0.01). No significant side-to-side differences were found in PA and malignant groups. For PA differentiation, ASLm and ASLmax yielded AUCs of 0.766 (p = 0.002) and 0.742 (p = 0.005), respectively. For WT differentiation, both parameters showed excellent performance, yielding AUCs of 0.774 (p < 0.001) and 0.769 (p = 0.002).Conlusions: While ASL perfusion MRI effectively differentiates common benign parotid tumors, its limitations in malignancy evaluation necessitate its integration into a multiparametric MRI protocol for a more reliable preoperative diagnosis.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1096-1104"},"PeriodicalIF":1.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147969571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between hearing severity and hematological findings at initial presentation in Meniere's disease. 听力严重程度与梅尼埃氏病初始血液学表现的关系

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-09-01 Epub Date: 2026-05-17 DOI: 10.1080/00016489.2026.2669377

Yoshihiro Nitta, Takaomi Kurioka, Kengo Yamamoto, Lingshuai Kong, Taku Yamashita

{"title":"Association between hearing severity and hematological findings at initial presentation in Meniere's disease.","authors":"Yoshihiro Nitta, Takaomi Kurioka, Kengo Yamamoto, Lingshuai Kong, Taku Yamashita","doi":"10.1080/00016489.2026.2669377","DOIUrl":"10.1080/00016489.2026.2669377","url":null,"abstract":"Background: Meniere's disease (MD) is characterized by progressive hearing loss; however, the factors determining its severity remain unclear.Aims/objectives: To investigate the clinical and hematological factors associated with hearing severity in MD.Materials and methods: This retrospective study included 112 patients with unilateral MD. Patients with bilateral disease or contralateral hearing loss ≥40 dB were excluded. Hearing severity was classified using AAO-HNS criteria based on pure-tone average (0.5, 1, 2, and 4 kHz), and patients were categorized into non-severe (stages I-II) and severe (stages III-IV) groups. Associations were analyzed using trend analysis, group comparisons, and multivariate logistic regression.Results: Twenty-one patients were classified as severe. Hearing thresholds in the affected ear were significantly higher at all frequencies in the severe group. In the contralateral ear, higher thresholds were observed at 4 and 8 kHz. Increased severity was associated with older age, longer disease duration, higher hemoglobin, hematocrit, and creatinine levels, and lower estimated glomerular filtration rate (eGFR) values. Multivariate analysis identified sex, hematocrit, and uric acid as independent factors.Conclusions and significance: Hearing severity in MD was associated with male sex, longer disease duration, and findings suggestive of hemoconcentration and renal function impairment, indicating the role of systemic conditions.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1112-1117"},"PeriodicalIF":1.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147961838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term hearing outcomes and prognostic factors in Meniere's disease. 梅尼埃氏病的长期听力结局和预后因素。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-09-01 Epub Date: 2026-05-16 DOI: 10.1080/00016489.2026.2665371

Ping-Chia Cheng, Cheng-Yang Chang, Tzu-Ang Chen, Po-Hsuan Wu, Chih-Ming Chang, Wu-Chia Lo, Li-Jen Liao, Po-Wen Cheng

{"title":"Long-term hearing outcomes and prognostic factors in Meniere's disease.","authors":"Ping-Chia Cheng, Cheng-Yang Chang, Tzu-Ang Chen, Po-Hsuan Wu, Chih-Ming Chang, Wu-Chia Lo, Li-Jen Liao, Po-Wen Cheng","doi":"10.1080/00016489.2026.2665371","DOIUrl":"10.1080/00016489.2026.2665371","url":null,"abstract":"Background: While the management of vertigo in Meniere's disease (MD) has been extensively studied, there is limited understanding of the long-term hearing prognosis and associated risk factors.Aims/objectives: To assess the long-term hearing outcomes and identify key factors influencing hearing prognosis in patients with MD.Materials and methods: A retrospective review was conducted on 159 patients (179 affected ears) with MD, with a minimum follow-up of six months. Hearing outcomes were classified based on four-tone (500, 1000, 2000, and 3000 Hz) averages (FTA) into stages. Univariate and multivariate analyses were performed to determine factors associated with post-treatment hearing stages.Results: The mean follow-up duration was 4.7 years. At baseline, 36% of patients had stage I/II hearing, whereas 64% had stage III/IV. Post-treatment, 33% remained at stage I/II, and 67% at stage III/IV. Multivariate analysis revealed two independent predictors of better hearing outcomes (stage I/II): younger age (<58 years) (OR 6.28, p < 0.001) and better pretreatment FTA (<50.0 dB) (OR 28.52, p < 0.001).Conclusions: Long-term hearing outcomes in MD are primarily influenced by age and baseline hearing status. Early intervention and treatment in patients with preserved hearing may improve prognosis. These insights can assist clinicians in risk stratification and tailoring individualized management strategies.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1084-1089"},"PeriodicalIF":1.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147959376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does smoking affect cortical auditory evoked potentials in young adults? 吸烟是否影响年轻人的皮层听觉诱发电位？

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-09-01 Epub Date: 2026-05-27 DOI: 10.1080/00016489.2026.2673532

Seval Ceylan, Gökçe Tanyeri Toker, Didem Erkan, Raşan Genç

{"title":"Does smoking affect cortical auditory evoked potentials in young adults?","authors":"Seval Ceylan, Gökçe Tanyeri Toker, Didem Erkan, Raşan Genç","doi":"10.1080/00016489.2026.2673532","DOIUrl":"10.1080/00016489.2026.2673532","url":null,"abstract":"Background: Cigarette smoking has vascular and neurotoxic effects that may influence auditory function, and cortical auditory evoked potentials (CAEPs) can reveal subtle central auditory changes even when peripheral hearing thresholds remain within reference limits.Objective: To investigate whether smoking influences CAEP responses in young adults with pure-tone hearing thresholds within reference limits.Methods: This cross-sectional comparative study included 47 young adults (18-25 years) with bilateral air-conduction thresholds ≤20 dB HL, divided into smoker (n = 26) and non-smoker (n = 21) groups. All participants were right-handed and had type A tympanograms. CAEPs were recorded using 1 kHz tone-burst stimuli at 65 dB nHL, and absolute latencies (P1, N1, P2) and peak-to-peak amplitudes (P1-N1, N1-P2) were analyzed for each ear. Group differences were assessed using independent samples tests (p < 0.05).Results: Compared to non-smokers, smokers had significantly prolonged right-ear P1 latency (p = 0.024) and reduced P1-N1 and N1-P2 amplitudes bilaterally (Right: p < 0.001 and p = 0.007, respectively; Left: p = 0.003 and p = 0.009, respectively).Conclusions: In normal-hearing young adults, cigarette smoking is associated with prolonged P1 latencies and reduced P1-N1/N1-P2 amplitudes. This indicates early thalamocortical disruption, highlighting CAEPs as sensitive markers for subclinical tobacco-induced auditory dysfunction.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1137-1143"},"PeriodicalIF":1.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148025535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical classification of non-syndrome congenital ossicular chain malformations. 无综合征先天性听骨链畸形的临床分型。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-08-27 DOI: 10.1080/00016489.2026.2720378

Yiqing Liu, Binjun Chen, Weixun Zhang, Shiyao Min, Ning Cong, Na Gao, Dongdong Ren, Rui Ma, Fanglu Chi

{"title":"Clinical classification of non-syndrome congenital ossicular chain malformations.","authors":"Yiqing Liu, Binjun Chen, Weixun Zhang, Shiyao Min, Ning Cong, Na Gao, Dongdong Ren, Rui Ma, Fanglu Chi","doi":"10.1080/00016489.2026.2720378","DOIUrl":"https://doi.org/10.1080/00016489.2026.2720378","url":null,"abstract":"Background: The existing classifications of congenital ossicular chain usually take the motility of the stapes footplate for differentiation, with a lack of attention on the concurrent malformations of facial nerve.Objectives: To explore the distribution of different types of congenital ossicular chain malformations and to propose a new classification for the guidance of clinical treatment.Material and methods: Preoperative examinations and intraoperative findings of patients with congenital ossicular chain malformations from 2014 to 2025 were retrospectively collected. Based on the traditional Teunissen and Yang classification, a new classification was further proposed according to the key anatomical structures concerned in clinical diagnosis and treatment.Results: A total of 119 patients with ossicular chain malformations were included in this study, 135 ears in total. The classification of patients in this study based on this new classification was as follows: 19 ears (14.1%) of type Ia, 60 ears (44.4%) of type Ib, 7 ears (5.2%) of type IIa, 33 ears (24.4%) of type IIb, 11 ears (8.1%) of type IIIa, and 5 ears (3.7%) of type IIIb.Conclusions and significance: Based on a large cohort study, this innovative classification that centering on abnormal stapes and facial nerve contributes much to clinical diagnosis and treatment of non-syndrome congenital ossicular chain malformations.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-10"},"PeriodicalIF":1.3,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148838760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment outcomes in patients with p16-negative oropharyngeal cancer: a comparison of initial surgery and definitive chemoradiotherapy. p16阴性口咽癌患者的治疗结果：初始手术和最终放化疗的比较

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-08-26 DOI: 10.1080/00016489.2026.2719394

Younghac Kim, Taek Yoon Cheong, Sang Hoo Park, Man Ki Chung, Han-Sin Jeong, Young-Ik Son, Nayeon Choi

{"title":"Treatment outcomes in patients with p16-negative oropharyngeal cancer: a comparison of initial surgery and definitive chemoradiotherapy.","authors":"Younghac Kim, Taek Yoon Cheong, Sang Hoo Park, Man Ki Chung, Han-Sin Jeong, Young-Ik Son, Nayeon Choi","doi":"10.1080/00016489.2026.2719394","DOIUrl":"https://doi.org/10.1080/00016489.2026.2719394","url":null,"abstract":"Background: p16-negative oropharyngeal squamous cell carcinoma (OPSCC) has a poorer prognosis than p16-positive disease, but evidence on optimal treatment and salvage-related morbidity remains limited.Aims and objectives: To compare outcomes of initial surgery-based treatment and definitive concurrent chemoradiotherapy (CCRT) in p16-negative OPSCC.Materials and methods: We retrospectively analyzed 103 patients with p16-negative OPSCC (2008-2020). Patients underwent surgery with or without adjuvant radiotherapy/chemoradiotherapy, or definitive CCRT. Clinical characteristics, oncologic outcomes, recurrence patterns, and complications were compared. Multivariable Cox models assessed recurrence-free and overall survival.Results: Age, sex, smoking status, and subsite did not differ significantly between groups, whereas T (p = 0.004) and N (p < 0.001) categories were lower in the surgery group. Recurrence and death rates (32.3% and 11.3% vs. 39.0% and 12.2%) and salvage survival did not differ significantly. Wound complications after salvage treatment were more frequent in the CCRT group (5/16, 31.2%) than in the surgery group (1/20, 5.0%; difference 26.3%, 95% CI 1.0-50.9%; p = 0.069).Conclusions and significance: Surgery-based and CCRT-based treatments achieved similar oncologic outcomes, but initial CCRT was associated with more wound complications after salvage treatment.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148816936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occult cervical nodal metastasis in surgically treated cN0 hypopharyngeal squamous cell carcinoma: prevalence and level-specific distribution in a Vietnamese cohort. 手术治疗的cN0下咽鳞状细胞癌的隐匿性宫颈淋巴结转移：越南队列的患病率和水平特异性分布。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-08-26 DOI: 10.1080/00016489.2026.2710563

Phuoc Tai Tran, Van Cuong Le, Van Manh Phan, Thi Kieu Trang Lu, Duc Toan Chau

{"title":"Occult cervical nodal metastasis in surgically treated cN0 hypopharyngeal squamous cell carcinoma: prevalence and level-specific distribution in a Vietnamese cohort.","authors":"Phuoc Tai Tran, Van Cuong Le, Van Manh Phan, Thi Kieu Trang Lu, Duc Toan Chau","doi":"10.1080/00016489.2026.2710563","DOIUrl":"https://doi.org/10.1080/00016489.2026.2710563","url":null,"abstract":"Background: Clinically node-negative (cN0) hypopharyngeal squamous cell carcinoma (HPSCC) carries a high risk of occult cervical nodal metastasis, but the data on its prevalence and level-specific distribution remain limited.Objectives: To determine the prevalence and level-specific distribution of occult cervical nodal metastasis and explore clinicopathological associations with occult nodal disease in surgically treated cN0 HPSCC.Materials and methods: In this retrospective surgical cohort, 28 patients with cN0 HPSCC underwent partial or total pharyngolaryngectomy with neck dissection between January 2020 and March 2026. Occult nodal metastasis was defined as postoperative histopathological pN + disease. Nodal distribution was mapped by neck level, and exploratory clinicopathological associations were examined using univariable Firth logistic regression.Results: Occult cervical nodal metastasis was identified in 11/28 patients (39.3%). Ipsilateral occult metastasis was observed in 10/28 patients (35.7%), with Levels II and III most frequently involved, followed by Level IV. In exploratory univariable analysis, medial wall invasion of the pyriform sinus was associated with occult nodal metastasis (unadjusted OR, 5.52; 95% CI, 1.12-27.30; p = 0.036).Conclusions and significance: Occult nodal metastasis is common in cN0 HPSCC and predominantly involves ipsilateral Levels II-IV. Medial wall invasion of the pyriform sinus showed an exploratory association with occult nodal metastasis and requires validation in larger prospective cohorts.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.3,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological analysis of parotid lesions: a single-center experience of 673 surgically treated patients. 腮腺病变的临床病理分析：673例手术治疗患者的单中心经验。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-08-25 DOI: 10.1080/00016489.2026.2719122

Demet Yazıcı, Şükrü Alper Otamış, Buket Şengül, Ahmet Batuhan Topçu, İlhami Yıldırım

{"title":"Clinicopathological analysis of parotid lesions: a single-center experience of 673 surgically treated patients.","authors":"Demet Yazıcı, Şükrü Alper Otamış, Buket Şengül, Ahmet Batuhan Topçu, İlhami Yıldırım","doi":"10.1080/00016489.2026.2719122","DOIUrl":"https://doi.org/10.1080/00016489.2026.2719122","url":null,"abstract":"Background: Parotid gland lesions comprise a wide range of pathological entities with diverse clinicopathological features.Aims/objectives: This study aimed to evaluate the demographic, surgical, cytological, and histopathological characteristics of 673 patients who underwent parotidectomy at a tertiary referral center over a 9-year period.Material and methods: Patients who underwent parotid surgery between May 2017 and May 2026 were retrospectively reviewed. Demographic, clinical, surgical, cytological, and histopathological data, including age, sex, lesion laterality, tumor size, surgical procedure, neck lymph node dissection status, fine-needle aspiration biopsy (FNAB) results, and histopathological diagnosis, were analyzed.Results: Warthin tumor (54.1%) and pleomorphic adenoma (39.4%) were the most common benign parotid lesions. Metastatic squamous cell carcinoma was the most frequent malignant histopathological diagnosis (26.8%), followed by mucoepidermoid carcinoma (11.6%) and carcinoma ex pleomorphic adenoma (10.7%). Warthin tumor demonstrated significant male predominance (81.4% vs 18.6%; p < 0.001). Fine-needle aspiration biopsy demonstrated strong concordance with histopathology (p < 0.001), with 77.8% sensitivity, 99.8% specificity, and 96.8% overall diagnostic accuracy.Conclusions and significance: Benign lesions predominate among parotidectomy patients, with Warthin tumor being the most common diagnosis. Although FNAB demonstrates high specificity and accuracy in predicting malignancy, non-diagnostic and false-negative results of FNAB necessitate correlation with clinical, radiological, and histopathological findings.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathological findings in biopsied leukoplakic lesions among patients with Reinke's edema undergoing office-based laser therapy: a case series. 在接受办公室激光治疗的Reinke水肿患者中活检的白斑病变的组织病理学发现：一个病例系列。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-08-25 DOI: 10.1080/00016489.2026.2714330

Abdul-Latif Hamdan, Marc Mourad, Randa Barazi, Lana Ghzayel, Zeina Maria Semaan, Maher Kasti, Patrick Abou Raji Feghali, Jessica Aoun

{"title":"Histopathological findings in biopsied leukoplakic lesions among patients with Reinke's edema undergoing office-based laser therapy: a case series.","authors":"Abdul-Latif Hamdan, Marc Mourad, Randa Barazi, Lana Ghzayel, Zeina Maria Semaan, Maher Kasti, Patrick Abou Raji Feghali, Jessica Aoun","doi":"10.1080/00016489.2026.2714330","DOIUrl":"https://doi.org/10.1080/00016489.2026.2714330","url":null,"abstract":"Background: Reinke's edema (RE) is a benign disease of the vocal folds. There are no reports on the prevalence of dysplasia in patients with RE undergoing office-based laser therapy.Aims/objective: To investigate the prevalence of dysplasia in patients with RE who underwent office-based laser therapy.Material and methods: The medical records of patients with RE who underwent office-based laser therapy between January 2023 and May 2026 were reviewed. Those who had mucosal lesions, leukoplakia, that were biopsied prior to laser therapy were included in this study. Demographic data included age, sex, smoking history, reflux history, and type of RE using the Yonekawa classification.Results: The medical records of 74 patients with RE were reviewed. Twelve patients (8 females and 4 males) met the inclusion criteria and were included in this study. The mean age was 59.59 ± 7.87 years. A total of 14 RE lesions were biopsied. The total prevalence of dysplasia was 50%. Low grade and high-grade dysplasia were noted in 4 and 3 out of the 14 specimens, respectively.Conclusion and significance: A substantial proportion of patients with RE undergoing office-based therapy had dysplastic mucosal changes. This should alert to the need for diligent examination and follow-up.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.3,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Nordic cohort study on cochlear implants and binaural hearing in single-sided deafness. 单侧耳聋患者人工耳蜗植入与双耳听力的北欧队列研究。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-08-14 DOI: 10.1080/00016489.2026.2704936

Kasper Dyre Rasmussen, Abigail Anne Kressner, Quirin Mühlberger, Niels Cramer West, Søren Foghsgaard, Michael Bille, Per Cayé-Thomasen

{"title":"A Nordic cohort study on cochlear implants and binaural hearing in single-sided deafness.","authors":"Kasper Dyre Rasmussen, Abigail Anne Kressner, Quirin Mühlberger, Niels Cramer West, Søren Foghsgaard, Michael Bille, Per Cayé-Thomasen","doi":"10.1080/00016489.2026.2704936","DOIUrl":"10.1080/00016489.2026.2704936","url":null,"abstract":"ObjectivesTo evaluate the effects of cochlear implantation on speech recognition in noise, sound localization, QoL, and tinnitus in adults with SSD.Material and methods: This retrospective cohort study with prospective follow-up included 12 adults with SSD who underwent cochlear implantation between 2015 and 2024 at a tertiary referral center. Assessments included the Danish Sentence Test (DAST), sound localization testing, and patient-reported outcome measures. Speech reception thresholds (SRTs), localization accuracy (RMSE), QoL (NCIQ), and tinnitus burden (THI) were evaluated.Results: Cochlear implantation significantly improved speech recognition in the head shadow condition, whereas no significant improvements were observed for binaural squelch or summation. Sound localization accuracy improved significantly. Total NCIQ and THI scores also improved significantly.Conclusions and significance: Cochlear implantation improved speech recognition in noise, sound localization, quality of life, and tinnitus burden in adults with SSD, supporting its use as an effective treatment option for selected patients.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0