Allogeneic composite amniotic membrane in tympanic membrane repair: a randomized parallel controlled study.

IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY
Anchi Sun, Rongrong Lv, Zhiwei Xing, Xiaomin Wang, Mingjie Zhang, Mengjun Wang, Qianqian Shao, Hui Li
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引用次数: 0

Abstract

Backgrounds: Composite amniotic membranes have been widely used in ophthalmology and orthopedics. For the repair of tympanic membrane perforation, the introduction of amniotic membrane is still under study.

Objectives: To analyse the effectiveness of a homograft composite amniotic membrane in tympanic membrane repair.

Methods: A total of 76 patients were recruited and randomly assigned to the experimental group (n = 39) and the control group (n = 37). The test group employed a composite amniotic membrane for the repair of the tympanic membrane, while the control group utilized cartilage from the auricular for the same purpose. The efficacy of composite amniotic membrane was evaluated through a comparative analysis of postoperative tympanic membrane healing, complications, and hearing recovery.

Results: Hearing improved significantly in both groups, but there was no significant difference between the two groups. The results of the postoperative pain scores demonstrated that the majority of patients were experiencing mild pain, with a notable discrepancy between the test group and the control group. Intraoperative bleeding time was also significantly lower in the test group than in the control group.

Conclusion: Allogeneic composite amniotic membrane can be used as a material for repairing tympanic membrane perforation, which can effectively improve postoperative hearing of patients.

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来源期刊
Acta Oto-Laryngologica
Acta Oto-Laryngologica 医学-耳鼻喉科学
CiteScore
2.50
自引率
0.00%
发文量
99
审稿时长
3-6 weeks
期刊介绍: Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.
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