Acta Oto-Laryngologica最新文献

Clinical characteristics of tuberculous otitis media: when to sound the alarm? 结核性中耳炎的临床特点：何时敲响警钟？

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-27 DOI: 10.1080/00016489.2025.2522899

Na Zhang, Danni Wang, Qijuan Zou, Xiaobo Ma, Yi Li, Yingshi Piao, Shouqin Zhao

{"title":"Clinical characteristics of tuberculous otitis media: when to sound the alarm?","authors":"Na Zhang, Danni Wang, Qijuan Zou, Xiaobo Ma, Yi Li, Yingshi Piao, Shouqin Zhao","doi":"10.1080/00016489.2025.2522899","DOIUrl":"https://doi.org/10.1080/00016489.2025.2522899","url":null,"abstract":"Background: Tuberculous otitis media (TOM) is a rare form of chronic otitis media, which presents diagnostic challenges due to nonspecific symptoms.Aims/objectives: To characterize the clinical features and identify strategies for early diagnosis.Materials and methods: A retrospective analysis was conducted on 32 patients (40 ears) diagnosed with TOM between 2002 and 2024. Clinical, audiologic, radiologic, and laboratory findings were reviewed.Results: Mean diagnostic delay was 28.9 months. Persistent otorrhea (90%) and hearing loss (HL) (100%) were predominant. Tympanic membrane findings varied: single perforation (70%), multiple (12.5%), and intact (17.5%). Granulations were universal. Age stratification revealed conductive HL and pneumatized mastoids predominated in patients <40 years, while mixed HL and mixed-type mastoid were more common in patients >40 years (p = 0.016, p = 0.005). Bone destruction was evident in 25% of the cases. Mastoid type correlated with HL patterns in non-destructive cases (p = 0.040). Interferon-gamma release assay (IGRA) and polymerase chain reaction (PCR) showed relatively high detection rates.Conclusions and significance: Early suspicion of TOM in refractory/recurrent otitis media, combined with IGRA/PCR screening, prompt imaging, and consideration of age-specific patterns, facilitates timely diagnosis. Surgical biopsy remains critical for confirmation. Integration of age-stratified clinical, laboratory, and radiological findings improves detection accuracy and patient outcomes.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of factors influencing the effective dose of intratympanic steroid injection of dexamethasone in idiopathic sudden sensorineural hearing loss. 影响特发性突发性感音神经性耳聋鼓室内类固醇注射地塞米松有效剂量的因素分析。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-26 DOI: 10.1080/00016489.2025.2521809

Zhengjie Zhu, Jianyong Chen, Shuna Li, Jun Yang, Wei Wei

{"title":"Analysis of factors influencing the effective dose of intratympanic steroid injection of dexamethasone in idiopathic sudden sensorineural hearing loss.","authors":"Zhengjie Zhu, Jianyong Chen, Shuna Li, Jun Yang, Wei Wei","doi":"10.1080/00016489.2025.2521809","DOIUrl":"https://doi.org/10.1080/00016489.2025.2521809","url":null,"abstract":"Background: Currently, Intratympanic steroid injection (ITSI) has been identified as a common method for delivering dexamethasone to the inner ear in idiopathic sudden sensorineural hearing loss (ISSNHL).Objective: This study analyzed factors influencing dexamethasone effective dose in ITSI, aiming to optimize injection protocols and efficacy assessment.Materials and methods: A total of 251 ISSNHL patients received ITSI with 5 mg dexamethasone, and drug leakage from the external auditory canal was quantified. The effects of Eustachian tube function (assessed via taste method), injection speed (5 vs. 10 s), and injection site (anteroinferior, posteroinferior, anterosuperior tympanic membrane) on the effective dose were evaluated. The pretreatment and posttreatment audiological examination results were collected, and the relationship between the effective dosage and the efficacy was analyzed.Results: Significantly higher median leakage (1.90 mg vs. 0.75 mg, p < 0.01) was showed in patients with bitter taste, indicating passive eustachian tube opening. However, injection speed and site had no significant impact on leakage (p > 0.05). No significant differences in hearing outcomes were observed between high (>3.5 mg) and low (≤3.5 mg) effective dose groups (p > 0.05).Conclusions and significance: ITSI effective dose primarily depends on eustachian tube function, and low-dose dexamethasone (sufficient to fill the tympanic cavity) is equally efficacious, suggesting simplified clinical protocols.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes of ossiculoplasty techniques. 听骨成形术的远期疗效。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-26 DOI: 10.1080/00016489.2025.2521807

Tankut Uzun, Hamdi Çaklı, Ercan Kaya, Mehmet Özgür Pınarbaşlı, Melek Kezban Gürbüz, Armağan İncesulu

{"title":"Long-term outcomes of ossiculoplasty techniques.","authors":"Tankut Uzun, Hamdi Çaklı, Ercan Kaya, Mehmet Özgür Pınarbaşlı, Melek Kezban Gürbüz, Armağan İncesulu","doi":"10.1080/00016489.2025.2521807","DOIUrl":"https://doi.org/10.1080/00016489.2025.2521807","url":null,"abstract":"Background: The ideal ossiculoplasty technique should effectively restore sound transmission, be surgically feasible, biocompatible, and stable. Currently, no single material fully meets these criteria in a cost-effective manner.Objectives: To evaluate and compare the long-term audiological outcomes of various ossiculoplasty techniques.Materials and methods: This retrospective study included 116 patients (aged 11-72) who underwent ossiculoplasty using cortical bone, bone cement, or titanium prostheses between 2013 and 2019. Preoperative and 2-year postoperative air and bone conduction thresholds (500-4000 Hz), air-bone gap (ABG), and hearing gains were analyzed.Results: Significant postoperative ABG improvement was observed in the malleus-incus, incus-stapes bone cement, TORP, and PORP groups (p < 0.05). Although hearing gain was noted in the malleus-stapes bone cement and cortical bone groups, the improvement was not statistically significant (p = 0.18 and p = 0.95, respectively). Hearing gain >10 dB was achieved in 76.5% of incus-stapes bone cement and 53% of TORP procedures.Conclusions and significance: Bone cement offers an effective and economical option for ossiculoplasty, particularly in incudostapedial repairs. Despite no statistically significant difference (p = 0.206), the favorable outcomes of TORP suggest it may be superior to cortical bone in patients with non-functional ossicular chains.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-5"},"PeriodicalIF":1.2,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical and prognostic relevance of supraorbital ethmoid cell involvement in frontal sinus inverted papilloma. 眶上筛细胞累及额窦内翻性乳头状瘤与手术及预后的关系。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-24 DOI: 10.1080/00016489.2025.2519017

Şenol Çomoğlu, Ahmet Özkan, Ömer Orak, Levent Aydemir, Bayram Şahin, Hakan Kara, Meryem Nesil Keleş Türel

{"title":"Surgical and prognostic relevance of supraorbital ethmoid cell involvement in frontal sinus inverted papilloma.","authors":"Şenol Çomoğlu, Ahmet Özkan, Ömer Orak, Levent Aydemir, Bayram Şahin, Hakan Kara, Meryem Nesil Keleş Türel","doi":"10.1080/00016489.2025.2519017","DOIUrl":"https://doi.org/10.1080/00016489.2025.2519017","url":null,"abstract":"Background: The supraorbital ethmoid cell (SOEC) is a pneumatized extension of the anterior ethmoid sinus that may harbor residual disease after surgery, making complete surgical clearance challenging.Objectives: To evaluate the surgical and prognostic relevance of SOEC involvement in frontal sinus (FS) inverted papilloma (IP), particularly its association with revision surgery and recurrence.Methods: Data from 147 IP patients, including 32 with FS involvement, were retrospectively reviewed to identify true FS origin, FS extension, and SOEC involvement based on operative records and CT scans.Results: True FS mucosal origin was identified in 2 patients (6.25%), while SOEC involvement was observed in 8 (25%), all of whom had prior surgeries. Among the 19 patients with previous surgeries, 8 (42.1%) had SOEC involvement, compared to none of the 13 without (p = 0.007). Patients with SOEC involvement underwent significantly more surgeries (median: 2 vs. 1; p = 0.041). True FS origin rates did not differ significantly (p = 0.345). After a median follow-up of 40.5 months, recurrence was not observed in patients with SOEC involvement (0/8), compared to 6 recurrences among those without (6/24; p = 0.149).Conclusions and significance: SOEC involvement was more common in revision cases and linked to multiple prior surgeries, highlighting its importance in surgical planning and follow-up.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is pharmaceutical treatment of noise-induced hearing loss a realistic option? Debate article. 药物治疗噪音性听力损失是一个现实的选择吗？争论的文章。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-13 DOI: 10.1080/00016489.2025.2509662

Ulf Rosenhall, Per Muhr, Maoli Duan

引用次数: 0

Global incidence, standardized mortality ratio, and risk factors for suicide in head and neck cancer versus other cancer population: a systematic review and meta-analysis. 头颈癌与其他癌症人群的全球发病率、标准化死亡率和自杀风险因素：系统回顾和荟萃分析

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-03 DOI: 10.1080/00016489.2025.2507695

Srivatsa Surya Vasudevan, Victor Albornoz Alvarez, Sydney Schwab, Lindsay Olinde, Cherie-Ann O Nathan

{"title":"Global incidence, standardized mortality ratio, and risk factors for suicide in head and neck cancer versus other cancer population: a systematic review and meta-analysis.","authors":"Srivatsa Surya Vasudevan, Victor Albornoz Alvarez, Sydney Schwab, Lindsay Olinde, Cherie-Ann O Nathan","doi":"10.1080/00016489.2025.2507695","DOIUrl":"https://doi.org/10.1080/00016489.2025.2507695","url":null,"abstract":"Background: Suicide incidence and risk factors in head and neck cancer (HNC) vary across studies.Objective: To evaluate suicide incidence, standardized mortality ratio (SMR), and predictors in HNC versus other cancers.Material and methods: PubMed, Embase, ScienceDirect, and Web of Science were systematically reviewed until February 2025. A random-effects meta-analysis assessed the outcomes.Results: Out of 1,186 screened articles, 21 studies with 33,768,815 cancer patients (HNC: 2,470,243; non-HNC: 31,298,572) were included (mean age: 66.1 ± 8.82 years). The pooled suicide incidence in HNC was 277.1 per 100,000 (95% CI: 217.5-336.6), the highest among cancer populations, with Asia reporting the highest rate (457.9 per 100,000). The standardized mortality ratio (SMR) for suicide in HNC was 2.62 (95% CI: 2.10-3.26, p < 0.0001), ranking fourth among tumors. Risk factors included age ≥65 years (HR = 1.07, p = 0.03), male gender (HR = 5.55, p < 0.0001), distant metastases (HR = 1.47, 95% CI: 1.14-1.90, p = 0.003), and regional spread (HR = 1.28, p = 0.03).Conclusion: HNC had the highest suicide incidence and ranked fourth in SMR among cancers. Our meta-analysis identified key positive and negative suicide predictors.Significance: This meta-analysis provides the current incidence and SMR statistics in HNC compared to the non-HNC population.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decoding cholesteatoma radiological dimensions: unveiling the discrepancy between CT and MRI imaging and development of a predictive model based on CT and MRI volume comparison. 解码胆脂瘤的影像学尺寸：揭示CT和MRI成像的差异，建立基于CT和MRI体积比较的预测模型。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-08 DOI: 10.1080/00016489.2025.2484560

Edoardo Covelli, Alessandro Bozzao, Piero Giuseppe Meliante, Chiara Filippi, Sofia Pizzolante, Haitham H Elfarargy, Andrea Romano, Maurizio Barbara

{"title":"Decoding cholesteatoma radiological dimensions: unveiling the discrepancy between CT and MRI imaging and development of a predictive model based on CT and MRI volume comparison.","authors":"Edoardo Covelli, Alessandro Bozzao, Piero Giuseppe Meliante, Chiara Filippi, Sofia Pizzolante, Haitham H Elfarargy, Andrea Romano, Maurizio Barbara","doi":"10.1080/00016489.2025.2484560","DOIUrl":"10.1080/00016489.2025.2484560","url":null,"abstract":"Background: Cholesteatoma (CHO) presents a significant threat to middle ear integrity, potentially leading to severe complications. Radiological assessment is crucial for understanding CHO anatomy, with high-resolution CT scans commonly used despite limitations in sensitivity and size overestimation. Recent advancements in non-echo planar imaging (EPI) diffusion-weighted imaging (DWI) MRI offer improved sensitivity, but accessibility issues persist.Objectives: The objective of this study is to compare CHO volume, as measured by CT scans, and the gold standard non-EPI DWI MRI.Materials and methods: A prospective clinical trial involving 39 participants with middle-ear CHO compared CT and non-EPI DWI MRI volumes. Patients underwent both imaging modalities, and volumes were measured using a co-registration technique.Results: Median CHO volumes measured by MRI and CT showed a notable difference. The Bland-Altman plot indicated one outlier, removed for further analysis. Linear regression suggested a correlation, with CT volumes overestimating MRI volumes by a factor of four.Conclusions: Our study establishes a formula to estimate CHO size, highlighting the tendency of CT scans to overestimate volumes. While non-EPI DWI MRI remains the gold standard for accurate measurements, our findings emphasize the complementary roles of CT and MRI in CHO diagnosis and post-surgical follow-up through fusion techniques.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"469-475"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcutaneous laryngeal ultrasound for long-term voice function and vocal fold evaluation after thyroidectomy: a prospective study. 经皮喉超声对甲状腺切除术后长期语音功能和声带评价的前瞻性研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-16 DOI: 10.1080/00016489.2025.2484792

Dan Gao, Li Yang, Yuling Duan, Yongyi Li, Chen Chen

{"title":"Transcutaneous laryngeal ultrasound for long-term voice function and vocal fold evaluation after thyroidectomy: a prospective study.","authors":"Dan Gao, Li Yang, Yuling Duan, Yongyi Li, Chen Chen","doi":"10.1080/00016489.2025.2484792","DOIUrl":"10.1080/00016489.2025.2484792","url":null,"abstract":"Background: Transcutaneous laryngeal ultrasound (TLUSG) has come up as a practical alternative to laryngoscopy for the diagnosis of vocal fold palsy (VFP), as it's non-invasive and capable for dynamic real-time evaluation.Aims/objectives: To assess the features of the vocal cord (VF) recovery process and the diagnostic significance of TLUSG for VFP during long-term follow-up on patients with voice disorders post-thyroidectomy.Material and methods: Fifty-seven patients with voice impairment following thyroidectomy were enrolled. The image features of VFs and the voice handicap index (VHI) scores were recorded at various intervals after surgery. Laryngoscopy was performed for comparison.Results: 75.4%(43/57) patients recovered voice function as assessed by VHI, 41 (71.9%) patients demonstrated recovery by TLUSG. Eighteen patients underwent laryngoscopy, and 14 were identified as VFP. The ultrasonic images of VFP presented with different manifestations at different periods after thyroidectomy. The diagnostic accuracy of TLUSG increased from 77.8% to 88.9% over time, whereas that of VHI exhibited a decrease. TLUSG and Laryngoscope were highly consistent (κ = 0.679), as were the evaluations of two physicians.Conclusions and significance: The TLUSG is an effective alternative to laryngoscopy in patients with vocal dysfunction following thyroidectomy.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"528-535"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supraglottoplasty and thriving in laryngomalacia. Is there a nexus? 声门上成形术治疗喉软化。两者之间有联系吗？

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-23 DOI: 10.1080/00016489.2025.2488487

Patrícia Silva Sousa, Gil Coutinho, António Andrade, Ricardo Vaz, Carla Pinto Moura, Jorge Spratley

{"title":"Supraglottoplasty and thriving in laryngomalacia. Is there a nexus?","authors":"Patrícia Silva Sousa, Gil Coutinho, António Andrade, Ricardo Vaz, Carla Pinto Moura, Jorge Spratley","doi":"10.1080/00016489.2025.2488487","DOIUrl":"10.1080/00016489.2025.2488487","url":null,"abstract":"Background: Feeding difficulties and failure to thrive are common findings in severe laryngomalacia.Aims: To evaluate the outcomes of supraglottoplasty for severe laryngomalacia and its impact on weight progression.Material and methods: Observational cohort study of paediatric patients with laryngomalacia who underwent supraglottoplasty from 2018 to 2023. Postoperative outcomes, including weight, were evaluated. Children with comorbidities affecting growth were excluded.Results: Thirty-eight children with severe laryngomalacia underwent supraglottoplasty, with 32 meeting the inclusion criteria; 59.4% were male. The mean age at diagnosis and surgery was 5.8 and 10.5 months, respectively. All cases of respiratory distress were resolved with surgery. In the weight evaluation, 18 patients (56.3%) had a preoperative percentile below 15, of whom ten were below the 5th percentile. A statistically significant increase was observed between preoperative percentile and consecutive postoperative percentiles at 1, 3 and 12 months. Regarding children with percentile below 15, 75% successfully crossed two percentile lines and 90% of children with failure to thrive managed to rise above the 5th percentile.Conclusions and significance: Supraglottoplasty leads to symptomatic improvement and a significant increase in weight percentile in patients with severe laryngomalacia. Growth curves adjusted for gender and age should be an objective measure of supraglottoplasty outcomes.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"536-539"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 修正。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-03-28 DOI: 10.1080/00016489.2025.2485730

引用次数: 0