Acta Oto-Laryngologica最新文献

Clinical features and management of head and neck castleman disease: a single-center retrospective analysis. 头颈部castleman病的临床特征和治疗：单中心回顾性分析

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-22 DOI: 10.1080/00016489.2025.2535436

Yifan Yang, Xue Zhang, Yang Zhang, Qi Zhong, Lizhen Hou, Shizhi He, Qian Shi, Yanming Zhao, Ru Wang, Jugao Fang, Ling Feng

{"title":"Clinical features and management of head and neck castleman disease: a single-center retrospective analysis.","authors":"Yifan Yang, Xue Zhang, Yang Zhang, Qi Zhong, Lizhen Hou, Shizhi He, Qian Shi, Yanming Zhao, Ru Wang, Jugao Fang, Ling Feng","doi":"10.1080/00016489.2025.2535436","DOIUrl":"https://doi.org/10.1080/00016489.2025.2535436","url":null,"abstract":"Background: Castleman disease, a rare lymphoproliferative disorder with diverse features, is often misdiagnosed due to rarity and similarity to malignancies.Aims: The study analyzed the clinicopathological characteristics, diagnostic challenges, and outcomes of head and neck Castleman disease (HNCD) to improve diagnostic accuracy and optimize management strategies.Material and methods: Retrospective study of 21 HNCD patients treated at Beijing Tongren Hospital (2007-2024). Demographics, presentation, imaging, histopathology, treatment, and outcomes were analyzed using t-tests, Mann-Whitney U, and Fisher's exact tests.Results: Mean age 36.1; 52.4% female. Mainly painless cervical masses (95.2%). Histology: 85.7% hyaline vascular, 14.3% plasma cell. Imaging showing non-specific hypoechoic nodules (ultrasound) and homogeneous enhancement (CT/MRI). Surgical excision (85.7%) achieved 76.2% complete remission (mean follow-up: 85.2 months). Tumor size (34.6 ± 15.3 mm) didn't correlate with outcome (p = 0.756). One plasma cell patient (4.8%) died of unrelated causes. No recurrences or malignant transformations were observed.Conclusions and significance: HNCDs are predominantly unicentric and can be cured with complete surgical resection. Due to the lack of specificity of imaging and laboratory findings, diagnosis relies on histopathology. Collaborations among multiple centers and molecular studies are essential to advancing the precision treatment of HNCD.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical treatment outcomes of naso-orbito-ethmoid fractures using 3D printing-assisted patient specific mesh: a prospective study. 使用3D打印辅助的患者特异性补片治疗鼻眶筛骨折的手术效果：一项前瞻性研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-17 DOI: 10.1080/00016489.2025.2527113

Taiqin Wang, Donghui Yan, Hongxun Gong, Ning Huang, Chunlan Lin, Maoxin Wang, Shiyan Chen

{"title":"Surgical treatment outcomes of naso-orbito-ethmoid fractures using 3D printing-assisted patient specific mesh: a prospective study.","authors":"Taiqin Wang, Donghui Yan, Hongxun Gong, Ning Huang, Chunlan Lin, Maoxin Wang, Shiyan Chen","doi":"10.1080/00016489.2025.2527113","DOIUrl":"https://doi.org/10.1080/00016489.2025.2527113","url":null,"abstract":"Background: This study aimed to investigate the efficacy of three-dimensional (3D) printing-assisted treatment for naso-orbito-ethmoid (NOE) fractures and to compare it with conventional surgical methods.Methods: This research conducted a retrospective analysis of 84 patients with NOE fractures who received surgical treatment at the 900th Hospital of Joint Logistics Support Force of the Chinese People's Liberation Army from January 2018 to July 2023. The patients were divided into two groups based on whether 3D printing was applied as the experimental group (n = 44) and the traditional group (n = 40). Surgical duration, hospital stay duration, intraoperative blood loss, postoperative visual analog scale (VAS) score, simotic index, and complications were compared.Results: The 3D printing group had a shorter average surgical time, average hospital stay duration, average indwelling time of drainage tube, intraoperative blood loss, postoperative pain and satisfaction VAS score, and complications compared to the traditional group. No statistically significant differences were found between the two groups in the simotic index after treatment.Conclusions: Compared to conventional surgical treatment, preoperative 3D printing-assisted treatment for adult patients with NOE fractures can significantly reduce surgical duration, intraoperative bleeding loss and complications, reducing surgical difficulty and improving surgical safety.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic thyroid and parathyroid surgery in Japan: a cohort study using a Japanese claims database. 内镜下甲状腺和甲状旁腺手术在日本：一项使用日本索赔数据库的队列研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-08 DOI: 10.1080/00016489.2025.2512028

Yo Kishimoto, Kayoko Mizuno, Yoshitaka Kawai, Akira Yoshizawa, Yoshiki Watanabe, Koji Kawakami, Koichi Omori

{"title":"Endoscopic thyroid and parathyroid surgery in Japan: a cohort study using a Japanese claims database.","authors":"Yo Kishimoto, Kayoko Mizuno, Yoshitaka Kawai, Akira Yoshizawa, Yoshiki Watanabe, Koji Kawakami, Koichi Omori","doi":"10.1080/00016489.2025.2512028","DOIUrl":"https://doi.org/10.1080/00016489.2025.2512028","url":null,"abstract":"Background: Minimally invasive techniques are increasingly required in neoplastic surgeries to enhance intraoperative safety and reduce post-operative complications. Endoscopic thyroid and parathyroid surgeries were introduced in the late twentieth century and have been covered by health insurance since 2016 in Japan.Aims/objectives: This study aimed to evaluate the frequency and risk factors for post-operative complications following endoscopic thyroid and parathyroid surgeries using a nationwide claims database in Japan.Material and methods: We conducted a retrospective cohort study by using an insurance claims database. Patients who underwent endoscopic thyroid or parathyroid surgery between April 2016 and December 2022 were included. The incidence of complications such as recurrent laryngeal nerve (RLN) palsy, hypocalcemia, post-operative hemorrhage, infection, and laryngeal edema was investigated. Univariable and multivariable logistic regression analyses were performed to examine risk factors for complications.Results: Overall, 274 patients were analyzed, with RLN palsy observed in 15 (5.47%), hypocalcemia in 14 (5.11%), and post-operative hemorrhage in 5 (1.82%) patients. Male sex was identified as a significant risk factor for post-operative hemorrhage, whereas total thyroidectomy was associated with hypocalcemia.Conclusions: Endoscopic thyroid and parathyroid surgeries in Japan have demonstrated favorable safety profiles with low complication rates.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic factors in myringoplasty: a single institution retrospective chart review. 鼓膜成形术的预后因素：单一机构回顾性图表回顾。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-04 DOI: 10.1080/00016489.2025.2522871

Vito Pontillo, Mauro Mastrodonato, Valentina Foscolo, Alessandra Pantaleo, Francesco Barbara, Nicola Quaranta

{"title":"Prognostic factors in myringoplasty: a single institution retrospective chart review.","authors":"Vito Pontillo, Mauro Mastrodonato, Valentina Foscolo, Alessandra Pantaleo, Francesco Barbara, Nicola Quaranta","doi":"10.1080/00016489.2025.2522871","DOIUrl":"https://doi.org/10.1080/00016489.2025.2522871","url":null,"abstract":"Background: Tympanic membrane perforation (TMP) is the result of recurrent or chronic otitis media, iatrogenic or traumatic events. It may sometimes require a surgical repair, known as myringoplasty, with the purpose of rebuilding a barrier between the external and middle ear, and restoring a good hearing level.Objective: The aim of this study is to identify the prognostic factors that may affect the outcomes of myringoplasty.Material and methods: A retrospective chart review was carried out by including all patients who had undergone myringoplasty for TMP in our Institution in the period between January 2017 and December 2021. All the potential prognostic factors were evaluated.Results: A global success rate of 90.1% was found, with a satisfying hearing recovery in 71.5% of cases. Reperforation was demonstrated to be more frequent in children, in patients with a poor educational level, in the presence of tympanosclerosis and involvement of the anterior half of the membrane.Conclusions and significance: Our data show that knowing the prognostic factors may help adapting the techniques and indications to every single case, thus improving the outcomes of myringoplasty.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival, efficacy and organ preservation outcomes of induction chemotherapy in sinonasal squamous cell carcinoma: a systematic review and meta-analysis. 鼻窦鳞状细胞癌诱导化疗的生存、疗效和器官保存结果：系统回顾和荟萃分析。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-03 DOI: 10.1080/00016489.2025.2520320

Srivatsa Surya Vasudevan, Nrusheel Kattar, Morni Modi, Manish D Mair, Ameya A Asarkar

{"title":"Survival, efficacy and organ preservation outcomes of induction chemotherapy in sinonasal squamous cell carcinoma: a systematic review and meta-analysis.","authors":"Srivatsa Surya Vasudevan, Nrusheel Kattar, Morni Modi, Manish D Mair, Ameya A Asarkar","doi":"10.1080/00016489.2025.2520320","DOIUrl":"https://doi.org/10.1080/00016489.2025.2520320","url":null,"abstract":"Background: Locally advanced sinonasal squamous cell carcinoma (SNSCC) is typically treated with surgery, adjuvant radiation, and possibly chemotherapy, but the role of induction chemotherapy (ICT) has not been extensively studied.Objective: The main objective was to assess the survival, efficacy, and organ preservation outcomes of ICT.Material and methods: National Institute for Health and Care Excellence (NICE) search domain, PubMed, Embase, and Medline were queried for articles from inception through December 2024. A random-effects meta-analysis of pooled response, survival and orbital preservation rates were assessed.Results: A total of 9 studies with 338 ICT patients were included. The pooled partial response (PR) rate was 57%. Complete response rates ranged from 2% to 17%, and stable response rates from 15% to 42%. Two-year overall survival was 78% (95% CI: 0.60-0.90) and disease-free survival was 93% (95% CI: 0.82-0.97). Orbital preservation rates were 83% (95% CI: 0.75-0.90).Conclusions: Pooled evidence suggests that ICT may be an effective modality in producing PR for locally advanced SNSCC. However, high-quality trials with standardized regimens are needed to confirm its role.Significance: This review provides the most updated statistical outcomes of ICT treatment in treating SNSCC which can help make decisions.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The postoperative relief of vertigo and migraine in Meniere's disease patients with and without migraine. 伴有和不伴有偏头痛的梅尼埃病患者术后眩晕和偏头痛的缓解。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-30 DOI: 10.1080/00016489.2025.2491651

Lin Han, Zijing Wang, Junbo Zhang, Maoli Duan, Tongxiang Diao, Lisheng Yu

{"title":"The postoperative relief of vertigo and migraine in Meniere's disease patients with and without migraine.","authors":"Lin Han, Zijing Wang, Junbo Zhang, Maoli Duan, Tongxiang Diao, Lisheng Yu","doi":"10.1080/00016489.2025.2491651","DOIUrl":"10.1080/00016489.2025.2491651","url":null,"abstract":"Background: The correlation of Meniere's disease (MD) and migraine remains unclear.Objectives: To explore the relation of MD and migraine by analyzing the postoperative relief of vertigo and migraine in MD patients with migraine.Material and methods: 104 MD patients were enrolled. The monthly vertigo episodes (MVE) and migraine headache index (MHI) were used for assessing effectiveness at pre- and post-endolymphatic sac decompression (ELSD). First, patients were divided into MD with migraine and MD two groups with vertigo relief rates compared. Then, the postoperative relief of vertigo and migraine in MD patients with migraine was analyzed.Results: The postoperative vertigo relief rates for MD and MD with migraine groups were 46.7% and 40.68% with no significant difference. In MD patients with migraine, postoperative MVE and MHI decreased significantly. The Kappa value calculated for vertigo and migraine outcomes was 0.505. The absence of hypertension was independently predictive of relief of vertigo and migraine. The male was independently predictive for relief of migraine.Conclusions and significance: ELSD is effective for MD patients with migraine. The postoperative relief of vertigo and migraine has a certain consistency, suggesting MD and migraine may share some common pathogenesis which may be related to inflammation.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"607-612"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving olfactory function and sinonasal manifestations in patients with granulomatosis with polyangiitis (GPA) - a prospective intervention study. 改善肉芽肿合并多血管炎（GPA）患者的嗅觉功能和鼻窦表现——一项前瞻性干预研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.1080/00016489.2025.2502564

Oliver Skjoedt Joergensen, Vitus Bugge Roennstad, Bo Baslund, Magne Bech, Ditte Gertz Mogensen, Kasper Aanaes

{"title":"Improving olfactory function and sinonasal manifestations in patients with granulomatosis with polyangiitis (GPA) - a prospective intervention study.","authors":"Oliver Skjoedt Joergensen, Vitus Bugge Roennstad, Bo Baslund, Magne Bech, Ditte Gertz Mogensen, Kasper Aanaes","doi":"10.1080/00016489.2025.2502564","DOIUrl":"10.1080/00016489.2025.2502564","url":null,"abstract":"Background: No guidelines exist and very few papers are written suggesting how to treat chronic rhinosinusitis (CRS) in granulomatosis with polyangiitis (GPA) patients.Aims and objectives: We conducted this prospective non-randomized intervention study to define the disease burden in GPA and to optimize the CRS treatment attempting to alleviate the symptoms with a special focus on whether the olfactory function could be improved.Materials and methods: We included 30 participants with GPA, who underwent olfactory training therapy combined with nasal corticosteroids twice a day for six months. At the first and second out-patient visits, the following data were collected: patients' CRS symptom were scored using a Visual Analog Scale (VAS), Sinonasal Outcome Test 22 (SNOT-22), Kennedy-Lund endoscopic score, and an olfactory threshold, discrimination, and identification (TDI) test.Results: The patients with few crusts and high compliance improved their olfactory function significantly. The total cohort improved their SNOT-22 score and the facial pain subdomain significantly. No significant improvements were made regarding the VAS score.Conclusions and significance: This study identified that GPA patients' CRS symptoms can be alleviated, using nasal corticosteroids and smell training therapy. Nevertheless, patients with GPA still have a high CRS-disease burden, mostly suffering from nasal crusting.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"640-647"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic hearing thresholds after glycerol ingestion may be modified by endolymphatic hydrops status in Ménière's disease. 摄入甘油后的动态听力阈值可能会因内淋巴积液状态而改变。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-16 DOI: 10.1080/00016489.2025.2489646

Hui Pan, Ping Lei, Qin Liu, Yingzhao Liu, Kaijun Xia, Xingqian Shen, Xiaoye Chen, Ziying Xu, Wenliang Fan, Yangming Leng, Bo Liu

{"title":"Dynamic hearing thresholds after glycerol ingestion may be modified by endolymphatic hydrops status in Ménière's disease.","authors":"Hui Pan, Ping Lei, Qin Liu, Yingzhao Liu, Kaijun Xia, Xingqian Shen, Xiaoye Chen, Ziying Xu, Wenliang Fan, Yangming Leng, Bo Liu","doi":"10.1080/00016489.2025.2489646","DOIUrl":"10.1080/00016489.2025.2489646","url":null,"abstract":"Background: Endolymphatic hydrops (ELH) can be identified by electrophysiological and radiological examinations.Objectives: We aimed to investigate the relationship between audiometric glycerol test and delayed magnetic resonance imaging (MRI) of the inner ear after intratympanic gadolinium in patients with unilateral Ménière's disease (MD).Material and methods: Forty-two patients with unilateral definite MD underwent audiometric glycerol test and delayed MRI following intratympanic gadolinium application.Results: The degree of cochlear ELH was moderately positively correlated with the mean hearing threshold below 2 kHz. For those ears with positive glycerol results, the best hearing threshold was measured at 3 h and the maximal improvement of hearing threshold was observed within the third hour. The overall positive rates of glycerol test did not differ between ELH (+) and ELH (-) subgroups based on the MRI findings. Significant temporal changes in the positive rate were only observed in the ELH (+) subgroup. The rebound rate did not change significantly over time in either subgroup.Conclusions and significance: In MD patients, glycerol-induced dynamic shift of hearing threshold may be modified by the hydropic status of the inner ear. For those without radiological ELH, glycerol test could be used as additional diagnostic tool to detect hydrops.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"563-570"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental study on the application of irreversible electroporation/nanoknife on tonsil tissues in a rabbit model. 不可逆电穿孔/纳米刀在兔扁桃体组织模型上应用的实验研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-23 DOI: 10.1080/00016489.2025.2491652

Xinggang Tao, Jiayan Chen, Zhuo Li, Yihui Sun, Chunyu Shan, Yingfeng Li, Qian Li, Quanqin Hao, Ying Li, Xizhi Yang, Keyong Li

{"title":"Experimental study on the application of irreversible electroporation/nanoknife on tonsil tissues in a rabbit model.","authors":"Xinggang Tao, Jiayan Chen, Zhuo Li, Yihui Sun, Chunyu Shan, Yingfeng Li, Qian Li, Quanqin Hao, Ying Li, Xizhi Yang, Keyong Li","doi":"10.1080/00016489.2025.2491652","DOIUrl":"10.1080/00016489.2025.2491652","url":null,"abstract":"Background: Irreversible electroporation (IRE)/nanoknife is a nonthermal technique for ablating solid tumors.Objectives: To investigate the application of IRE for ablating tonsil tissues in a rabbit model.Material and methods: Forty five rabbits were divided into three groups IRE, radiofrequency ablation (RFA) and control group. The IRE group received IRE in one or both tonsils, while the RFA group received IRE in one tonsil and RFA in the other. The control group had no operation. Rabbits were euthanized at days 1, 3, 7, 14, and 28 post-IRE ablation or RFA. White blood cell (WBC) counts, C-reactive protein (CRP), and creatine kinase (CK) levels were monitored and tonsil tissues were histologically examined.Results: IRE ablation induced cell apoptosis in tonsil tissues, which was most pronounced at 72 h post-treatment. At 14- and 28-days post-IRE ablation, lymphoid follicles regenerated in the tonsil tissues. The RFA group showed more severe injury and less tissue regeneration. Transient increases in WBC, CRP, and CK levels indicated inflammation and cardiac injury induced by IRE.Conclusions and significance: IRE is a potential modality for ablating tonsil tissues, which avoids thermal injury and preserving blood vessels. More robust studies with other animal models are required for definitive evidence.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"654-660"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traditional and adaptive speech audiometry in single-sided deaf (SSD) subjects rehabilitated by bone conductive implants (BCI), quality of life and long-term utilization. 单侧耳聋经骨传导植入（BCI）康复者的传统和自适应语音测听、生活质量和长期使用。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-17 DOI: 10.1080/00016489.2025.2504032

Edoardo Covelli, Chiara Filippi, Francesco Lazzerini, Elisabetta Tromboni, Silvia Tarentini, Sofia Pizzolante, Francesca Forli, Stefano Berrettini, Luca Bruschini

{"title":"Traditional and adaptive speech audiometry in single-sided deaf (SSD) subjects rehabilitated by bone conductive implants (BCI), quality of life and long-term utilization.","authors":"Edoardo Covelli, Chiara Filippi, Francesco Lazzerini, Elisabetta Tromboni, Silvia Tarentini, Sofia Pizzolante, Francesca Forli, Stefano Berrettini, Luca Bruschini","doi":"10.1080/00016489.2025.2504032","DOIUrl":"10.1080/00016489.2025.2504032","url":null,"abstract":"Background: Single-sided deafness (SSD) encompasses the presence of a profoundly deaf ear with a normal, contralateral one. Patients with SSD may have difficulty with speech intelligibility in noise and localizing sounds.Aims/objectives: This retrospective study aims to evaluate the long-term effectiveness of bone conduction implant (BCI) in a group of patients with SSD.Material and methods: Audiologic benefit was assessed through conventional speech audiometry and adaptive Matrix test. Impact on quality of life was evaluated with the Glasgow Benefit Inventory (GBI) questionnaire. BCI usage data were also obtained from each subject.Results: Thirty-two patients were included. No statistically significant improvements were found at standard audiometric tests using BCI, but at Matrix test the mean SRT is reached at S/N -1.16 dB without BCI and -2.07 with BCI with a statistically significant difference (p = 0.026). The mean GBI score was 25.12, ranging from -8.3 to 47.2. Ten subjects (31%) discontinued the BCI use overtime.Conclusions and significance: Benefit assessment of BCI in SSD recipients can be difficult. Adaptive audiometric test could be useful. Quality of life measures seem to suggest potential 'beyond-auditory' benefits. SSD recipients can be inconsistent users of BCI.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"633-639"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0