{"title":"Efficacy of endoscopic single-session corticosteroid delivery via round window membrane for severe to complete sudden deafness salvage: a prospective cohort study.","authors":"Siyu Li, Dingding Liu, Yuqin Xu, Hao Wu, Guangjie Zhu, Han Zhou, Junru Yan, Maoli Duan, Xiaoyun Qian, Ao Li, Xia Gao","doi":"10.1080/00016489.2026.2757448","DOIUrl":"https://doi.org/10.1080/00016489.2026.2757448","url":null,"abstract":"<p><strong>Background: </strong>Sudden sensorineural hearing loss (SSNHL) often necessitates salvage therapy when unresponsive to systemic corticosteroids.</p><p><strong>Aims/objectives: </strong>We introduce a novel endoscopic-assisted surgical approach for precise, single-session inner ear drug delivery via the round window membrane to treat refractory SSNHL.</p><p><strong>Material and methods: </strong>Patients underwent surgery for local administration of methylprednisolone through the round window membrane. And audiometry, CT scans and the severity of tinnitus and dizziness were evaluated during the follow-up period.</p><p><strong>Results: </strong>56 patients with severe-to-complete SSNHL were recruited, and the overall efficacy reached 55.4%. Mean Pure-Tone Average (PTA) threshold improved from 91.61 ± 11.37 dB to 76.79 ± 19.52 dB after 3 months (p < 0.0001). Among which, patients with profound and complete hearing loss exhibited substantial recovery, with average PTA reduction of 18.13 ± 18.51 dB (p = 0.0001) and 13.87 ± 10.20 (p < 0.0001), separatively. Timely intervention was also critical, the 13-day cutoff derived from ROC analysis represents a critical therapeutic window for salvage. Tinnitus and vertigo symptoms significantly improved after treatment (p < 0.0001). No treatment-related adverse events were observed.</p><p><strong>Conclusions and significance: </strong>This approach provides a new, promising paradigm for the salvage treatment of refractory severe-to-complete SSNHL.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149332048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erdem Ersan Akyürek, Büşra Kaplan, Erim Pamuk, Oğuz Kuşcu
{"title":"Primary cervical ganglioneuroblastoma: diagnostic challenges, management, and outcomes - a systematic review.","authors":"Erdem Ersan Akyürek, Büşra Kaplan, Erim Pamuk, Oğuz Kuşcu","doi":"10.1080/00016489.2026.2757485","DOIUrl":"https://doi.org/10.1080/00016489.2026.2757485","url":null,"abstract":"<p><strong>Background: </strong>Primary cervical ganglioneuroblastoma is rare, mimics paediatric neck lesions and abuts neurovascular structures.</p><p><strong>Aims/objectives: </strong>To synthesize individual-patient data on presentation, diagnosis, histology, treatment, morbidity and outcome.</p><p><strong>Material and methods: </strong>Following PRISMA 2020, PubMed, Scopus and Web of Science were searched on 10 May 2026; two reviewers independently selected reports and extracted data.</p><p><strong>Results: </strong>Eighteen reports described 24 patients; with an illustrative case, 25 were analysed (median age 4.5 years). Tumours involved the parapharyngeal (32%), retropharyngeal (24%) and carotid (16%) spaces. Subtype was intermixed in 10, nodular in three and unspecified in 12. Twenty-four underwent resection; seven received chemotherapy. Postoperative Horner syndrome was reported in 12 of 21 patients without documented preoperative Horner syndrome. At last assessment, 20 had no active disease, two had residual disease and one had died. In an exploratory analysis (<i>n</i> = 11), median diameter did not differ by Horner status (5.80 vs 5.45 cm; <i>p</i> = 0.982).</p><p><strong>Conclusions and significance: </strong>Cervical ganglioneuroblastoma should be considered in children with deep-neck masses. Core-needle biopsy may provide more adequate tissue than fine-needle aspiration when tissue diagnosis is required. Favourable outcomes of intermixed tumours apply only to cases with known subtype, and surgery should aim for maximal safe resection.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.3,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149340252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenxi Qiu, Qiujing Zhang, Rong Wang, Tianxing Zhang, Jialin Fan, Qiuchen Zheng, Yang Zhang, Shunli Li, Weidong Shen, Guojian Wang, Dongyi Han
{"title":"Frequency-Specific hearing changes in vestibular schwannoma and the greater sensitivity of ABR in small tumors.","authors":"Wenxi Qiu, Qiujing Zhang, Rong Wang, Tianxing Zhang, Jialin Fan, Qiuchen Zheng, Yang Zhang, Shunli Li, Weidong Shen, Guojian Wang, Dongyi Han","doi":"10.1080/00016489.2026.2752666","DOIUrl":"https://doi.org/10.1080/00016489.2026.2752666","url":null,"abstract":"<p><strong>Background: </strong>Vestibular schwannoma (VS) is a benign vestibular nerve tumor. The association between tumor size and auditory dysfunction, especially in small VSs, remains unclear.</p><p><strong>Objectives: </strong>To assess audiological changes with increasing tumor size in VS and identify tumor-size thresholds related to hearing impairment.</p><p><strong>Material and methods: </strong>We retrospectively analyzed 430 patients with sporadic VS treated between 2008 and 2025. Patients were classified by Koos grade. Clinical features, pure-tone audiometry, speech discrimination score, auditory brainstem response (ABR), and magnetic resonance imaging findings were reviewed. Multivariate regression and receiver operating characteristic analyses were performed.</p><p><strong>Results: </strong>Annual detection of small VS (Koos I-II) increased substantially. Hearing deteriorated with rising Koos grade, showing high-frequency impairment. Pure-tone and speech discrimination were comparable between Koos I and II, whereas ABR differed significantly; over 60% of Koos I patients with serviceable hearing had abnormal ABR. ROC identified thresholds of 17.4 mm for loss of serviceable hearing and 13.4 mm for ABR abnormality.</p><p><strong>Conclusions and significance: </strong>Audiological impairment worsens progressively as VS growth, with clear differences between small and medium-to-large tumors. ABR has superior sensitivity for early retrocochlear dysfunction in small VS and may serve as a preoperative predictor for hearing preservation to support clinical decision-making.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-13"},"PeriodicalIF":1.3,"publicationDate":"2026-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149316996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-reported experience with intratympanic corticosteroid injections in sudden hearing loss: a single-centre prospective study.","authors":"Simon Tsegaye, Elsa Erixon","doi":"10.1080/00016489.2026.2749996","DOIUrl":"https://doi.org/10.1080/00016489.2026.2749996","url":null,"abstract":"<p><strong>Background: </strong>Intratympanic corticosteroid (ITC) injections are recommended as salvage therapy for patients with incomplete recovery 2-6 weeks after the onset of sudden sensorineural hearing loss (SSHL).</p><p><strong>Aims/objectives: </strong>To evaluate patient experiences with ITC therapy and assess treatment side effects.</p><p><strong>Material and methods: </strong>Fifteen patients with SSHL eligible for ITC therapy were prospectively enrolled and received a total of 43 ITC injections. They completed questionnaires on treatment- and disease-related symptoms and side effects, rated using a visual analogue scale (VAS), before and after each injection and at 2-week and 3-month follow-up. Audiometric outcomes were assessed.</p><p><strong>Results: </strong>Treatment-related discomfort was low, with mean VAS scores <2 for pain at anaesthesia application and <3 for pain at injection. Twelve patients found the treatment worth the effort, and none regretted participating in the study. Two weeks after the last injection, none of the patients reported residual side effects; however, many patients reported residual hearing loss, sensitivity to sound, tinnitus, and dizziness also at the 3-month follow-up.</p><p><strong>Conclusions and significance: </strong>ITC treatment was well-tolerated by patients. The symptoms reported at 3 months after SSHL onset highlights the need for future SSHL studies to address tinnitus, sound sensitivity, and dizziness in addition to hearing recovery.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.3,"publicationDate":"2026-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149316998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazli Akkaya Kurt, Özlem Ertuğrul, Sadiye Murat Acar, Mahmut Tayyar Kalcıoğlu, Alper Köycü
{"title":"Functional and gain-based vestibulo-ocular measures across serum 25(OH)D categories: a dissociation between fHIT performance and vHIT gain.","authors":"Nazli Akkaya Kurt, Özlem Ertuğrul, Sadiye Murat Acar, Mahmut Tayyar Kalcıoğlu, Alper Köycü","doi":"10.1080/00016489.2026.2755224","DOIUrl":"https://doi.org/10.1080/00016489.2026.2755224","url":null,"abstract":"<p><strong>Background: </strong>Conventional vestibular tests quantify canal and otolith function, whereas the functional head impulse test (fHIT) measures how effectively the vestibulo-ocular reflex stabilizes vision during high-acceleration head motion. Low 25-hydroxyvitamin D [25(OH)D] has been linked to otolith dysfunction, but its relation to functional performance is unknown.</p><p><strong>Objectives: </strong>To compare otolith, canal and functional measures across serum 25(OH)D categories in adults without overt vestibular disease.</p><p><strong>Materials and methods: </strong>Thirty-nine adults aged 18-65 years with normal hearing were stratified by serum 25(OH)D into three groups of 13 (<20, 20-29.9, ≥30 ng/mL). All underwent audiometry, videonystagmography, cVEMP, oVEMP, vHIT and fHIT. Kruskal-Wallis and Mann-Whitney U tests were used.</p><p><strong>Results: </strong>fHIT correct response rates differed for posterior (<i>p</i> = 0.001) and anterior canals (<i>p</i> = 0.019), being lowest at <20 ng/mL; lateral performance was preserved (<i>p</i> = 0.234). All vHIT gains remained within acceptable limits and only anterior canal gain differed (<i>p</i> = 0.001). VEMP latencies were comparable; cVEMP amplitude asymmetry differed (<i>p</i> = 0.023) but opposite to expectation and within normal range.</p><p><strong>Conclusions and significance: </strong>Low 25(OH)D was accompanied by reduced functional vestibulo-ocular performance in the vertical canal planes despite normal gains. fHIT may capture subclinical change that vHIT gain does not.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-5"},"PeriodicalIF":1.3,"publicationDate":"2026-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149316997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeong Hun Jang, Jungho Ha, You-Jeong Kim, Hun Yi Park, Yun-Hoon Choung
{"title":"Clinical and behavioral delineation of cochlear implant non-users: a 20-year retrospective descriptive analysis.","authors":"Jeong Hun Jang, Jungho Ha, You-Jeong Kim, Hun Yi Park, Yun-Hoon Choung","doi":"10.1080/00016489.2026.2755205","DOIUrl":"https://doi.org/10.1080/00016489.2026.2755205","url":null,"abstract":"<p><strong>Background: </strong>Although cochlear implants (CIs) effectively restore hearing, device abandonment ('non-use') remains a critical challenge limiting long-term auditory rehabilitation.</p><p><strong>Aims/objectives: </strong>This study aimed to evaluate the prevalence, clinical and radiological characteristics, and patient-reported reasons for CI non-use, comparing pre-lingually and post-lingually deafened individuals to inform long-term retention strategies.</p><p><strong>Material and methods: </strong>We retrospectively reviewed 545 CI recipients implanted between 2002 and 2023 (excluding 24 patients lost to follow-up or with incomplete data). Clinical features, temporal bone CT, internal auditory canal MRI, and speech-language therapy records of 36 non-users were analyzed.</p><p><strong>Results: </strong>Overall non-use rate was 6.6% (36/545), comprising 8.7% (25/287) in pre-lingual and 4.3% (11/258) in post-lingual recipients. Inner ear anomalies were identified in 11 pre-lingual non-users, including two with isolated cochlear nerve deficiency. Primary non-use reasons were sound maladaptation (48.0% pre-lingual vs. 36.4% post-lingual) and lack of subjective listening effect (48.0% vs. 18.2%). Post-lingual non-users presented distinct adult-specific psychosocial barriers (27.3%), including depression and cognitive decline.</p><p><strong>Conclusions and significance: </strong>CI non-use is driven by distinct physiological, psychological, and socioeconomic factors depending on deafness onset. Delineating these onset-specific profiles provides essential guidance for tailored preoperative counseling and age-appropriate post-implantation monitoring to minimize long-term device abandonment.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2026-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149316995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between sleep-related breathing Disorder symptoms and parasomnias in children with adenoid hypertrophy scheduled for adenoidectomy.","authors":"Pınar Tekin, Zeynep İskender Emekli, Sevilay Hançer Tecimer","doi":"10.1080/00016489.2026.2700009","DOIUrl":"10.1080/00016489.2026.2700009","url":null,"abstract":"<p><strong>Background: </strong>Sleep-related breathing disorders (SRBD) in children are frequently associated with adenoid hypertrophy. A correlation has been identified between SRBD and numerous sleep-related disturbances, such as parasomnias. However, the relationship between SRBD symptoms and parasomnias in children undergoing adenoidectomy remains poorly understood.</p><p><strong>Aims: </strong>This study was designed to investigate the relationship between SRBD symptoms and parasomnias in children undergoing adenoidectomy.</p><p><strong>Materials and methods: </strong>In this study of 54 pediatric patients with adenoid hypertrophy, sleep symptoms and disturbances were measured <i>via</i> the Pediatric Sleep Questionnaire -Related Breathing Disorder (PSQ-SRBD) and Sleep Disturbance Scale for Children (SDSC) scales. Parasomnias (e.g. enuresis, sleepwalking) were documented through parental reports, followed by correlation analyses and group comparisons between symptomatic and asymptomatic children.</p><p><strong>Results: </strong>Analysis revealed a significant positive relationship between PSQ-SRBD and SDSC scores (<i>r</i> = 0.577, <i>p</i> < 0.001). Children with parasomnia symptoms demonstrated higher PSQ-SRBD and SDSC scores compared to those without parasomnias. Parasomnias were frequently reported among children with prominent SRBD symptoms.</p><p><strong>Conclusions and significance: </strong>Higher SRBD symptom burden is associated with increased prevalence of parasomnias. Overall, these findings underscore the need for comprehensive evaluation of sleep disturbances in pediatric patients undergoing adenoidectomy.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1405-1412"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148434715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2026-11-01Epub Date: 2026-07-30DOI: 10.1080/00016489.2026.2705488
Christina Youssef, Christian Salameh, Souheil Hallit, Charlie Hanna
{"title":"Postoperative complications in children with clinically diagnosed sleep-disordered breathing undergoing tonsillectomy.","authors":"Christina Youssef, Christian Salameh, Souheil Hallit, Charlie Hanna","doi":"10.1080/00016489.2026.2705488","DOIUrl":"10.1080/00016489.2026.2705488","url":null,"abstract":"<p><strong>Background: </strong>Children with clinically diagnosed sleep-disordered breathing (SDB)are at higher risk of respiratory complications following tonsillectomy. Decision to admit for surveillance post-operatively depends on variable patient-related factors. Further studies to find additional considerations can help refine the decision-making process, ultimately improving patient safety.</p><p><strong>Aims/objectives: </strong>To compare the rate of post-operative respiratory complications (PoRCs) between different surgical techniques and methods in children with clinically diagnosed SDB undergoing tonsillectomy.</p><p><strong>Material and methods: </strong>A retrospective study was conducted, including 139 children aged 6 months to 18 years who underwent tonsillectomy between January 2021 and June 2024 at three hospitals in Lebanon. Patients were compared according to postoperative respiratory complication status: 45 patients with PoRCs and 94 without PoRCs.</p><p><strong>Results: </strong>Undergoing the cautery method compared to coblation, undergoing total vs partial tonsillectomy, and higher ventilation rate had a significant association with higher odds of PoRCs.</p><p><strong>Conclusions and significance: </strong>In children with clinically diagnosed SDB undergoing tonsillectomy, the surgical technique, method, and airway management were significantly associated with the rate of PoRCs. Adequate choice of technique and method may be associated with reduced PoRCs in children with clinically diagnosed SDB undergoing tonsil surgery. These findings can assist clinicians in making informed decisions regarding post-operative care to reduce risks and improve clinical outcomes.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1458-1467"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148617868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CT imaging parameters of the oval window region can predict the extent of stapes footplate exposure in patients with otosclerosis.","authors":"Xia Zhu, Wenwen Zhou, Yongjing Lai, Xuesong Wang, Lei Liu, Lihong Xie, Songhua Tan, Anzhou Tang","doi":"10.1080/00016489.2026.2691961","DOIUrl":"10.1080/00016489.2026.2691961","url":null,"abstract":"<p><strong>Background: </strong>Stapedotomy, including classic stapedotomy (CS) and reversed stapedotomy (RS), is the primary surgery for otosclerosis. RS is preferred when the stapes suprastructure is preserved and footplate exposure is adequate.</p><p><strong>Objectives: </strong>To explore the correlation between stapes footplate exposure and CT imaging parameters of the oval window region, and assess their value in preoperative surgical planning.</p><p><strong>Materials and methods: </strong>A retrospective study of 166 otosclerosis surgeries (105 RS, 61 CS) performed by a single senior surgeon (2018-2025) was conducted. Reconstructed preoperative temporal bone HRCT scans with multiplanar reconstructions were used to measure the relative positions of the stapes and its surrounding structures, followed by analysis of their predictive value for surgical selection.</p><p><strong>Results: </strong>Between the two groups, postoperative hearing outcomes were comparable, while the CS group had a higher incidence of floating footplate. Stapes footplate width (SFW) and distance between the facial nerve and the long axis of the stapes (FNSL) emerged as independent predictors, with respective cutoffs of 1.13 mm and 0.73 mm.</p><p><strong>Conclusion and significance: </strong>RS yields fewer surgical complications. Preoperative HRCT measurements of SFW and FNSL can predict the degree of stapes footplate exposure and facilitate preoperative surgical planning.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1350-1358"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148350314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2026-11-01Epub Date: 2026-07-14DOI: 10.1080/00016489.2026.2700011
Yunlong Bai, Liyan Chen, Hong Zhao, Denghua Yang, Jie Li, Boxuan Wang
{"title":"Characteristics and efficacy of canalith-repositioning maneuvers for benign paroxysmal positional vertigo in very elderly patients.","authors":"Yunlong Bai, Liyan Chen, Hong Zhao, Denghua Yang, Jie Li, Boxuan Wang","doi":"10.1080/00016489.2026.2700011","DOIUrl":"10.1080/00016489.2026.2700011","url":null,"abstract":"<p><strong>Background: </strong>Benign paroxysmal positional vertigo (BPPV) is highly prevalent in very elderly patients (aged ≥80 years), who present complex comorbidities, atypical manifestations, poor mobility, and high fall risk, leading to diagnostic and therapeutic challenges. Evidence on this population is scarce.</p><p><strong>Aims/objectives: </strong>To clarify clinical features, treatment efficacy, recurrence patterns, and risk factors in very elderly BPPV patients.</p><p><strong>Material and methods: </strong>Retrospective analysis of 128 very elderly patients with BPPV.</p><p><strong>Results: </strong>Treatment was tolerated by 93.75% (120/128); cure and improvement rates were 93.3% (112/120) and 97.5% (117/120), respectively. The crude recurrence rate was 23.2% (26/112); 76.9% of recurrences were ipsilateral, with 69.2% involving the same canal. Kaplan-Meier estimates, accounting for censored observations, yielded cumulative recurrence rates of 6.3% (95% CI: 1.7%-10.6%) at 1 month, 14.3% (95% CI: 7.6%-20.5%) at 3 months, 18.2% (95% CI: 10.7%-25.1%) at 6 months, and 24.4% (95% CI: 15.3%-32.7%) at 12 months. Multivariable Cox regression identified prior BPPV (HR = 2.416, <i>p</i> = 0.039) and sleep disturbance (HR = 2.448, <i>p</i> = 0.028) as independent predictors.</p><p><strong>Conclusions and significance: </strong>Very elderly patients (aged ≥80 years) with BPPV show high treatment tolerance and favorable outcomes. Prior BPPV and sleep disturbance are independent predictors of recurrence. Individualized repositioning strategies are recommended.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1413-1421"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148443711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}