Acta Oto-Laryngologica最新文献

Chronic rhinosinusitis with nasal polyps: predictors of recurrence 5 years after surgery. 伴有鼻息肉的慢性鼻炎：术后 5 年复发的预测因素。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-11-15 DOI: 10.1080/00016489.2024.2424962

Pedro Marques Gomes, Diogo Cunha Cabral, Joana Barreto, André Alves Carção, Delfim Duarte, José Ferreira Penêda

{"title":"Chronic rhinosinusitis with nasal polyps: predictors of recurrence 5 years after surgery.","authors":"Pedro Marques Gomes, Diogo Cunha Cabral, Joana Barreto, André Alves Carção, Delfim Duarte, José Ferreira Penêda","doi":"10.1080/00016489.2024.2424962","DOIUrl":"https://doi.org/10.1080/00016489.2024.2424962","url":null,"abstract":"Backgrounds: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a medical condition characterized by persistent inflammation of the nasal mucosa and sinuses, accompanied by the presence of nasal polyps. When medical treatments prove ineffective, endoscopic sinus surgery (ESS) is recommended, yielding variable outcomes and recurrence rates ranging from 5% to 60%.Aims/objectives: The primary objectives of this study were to evaluate the outcomes of ESS and to identify independent predictors of recurrence and revision surgery.Material and methods: Retrospective cross-sectional study, focusing on patients diagnosed with CRSwNP who underwent ESS with a minimum follow-up period of 60 months. Various variables were collected. Multivariate and regression analyses were employed to assess the predictors associated with both recurrence and revision surgery.Results: The study analyzed 130 patients. The 5-year recurrence rate was 35.4%, and 17.7% of patients required revision surgery. These variables included asthma (p < 0.001), frontal sinus involvement (p < 0.001), Lund-Mackay score (p < 0.001), Endoscopic Nasal Polyps Score (p < 0.001), and eosinophilia in peripheral blood (p < 0.001). All the variables mentioned above were identified as predictors of recurrence and revision surgery.Conclusions and significance: Asthma, frontal sinus involvement, increased eosinophilia in peripheral blood, and a higher score on the LM system and NPS are poor prognostic factors in CRSwNP.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extent of abscess development in cervical abscesses and pathogenic bacteria related to swallowing function. 宫颈脓肿的脓肿发展程度以及与吞咽功能有关的致病菌。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-11-14 DOI: 10.1080/00016489.2024.2425764

Aya Katsura, Ryoukichi Ikeda, Masato Suzuki, Iori Kusaka, Shinsuke Kaneshiro, Toshihiko Abe, Shigeru Kuwashima, Katsunori Katagiri, Jun Suzuki, Kiyoto Shiga

{"title":"Extent of abscess development in cervical abscesses and pathogenic bacteria related to swallowing function.","authors":"Aya Katsura, Ryoukichi Ikeda, Masato Suzuki, Iori Kusaka, Shinsuke Kaneshiro, Toshihiko Abe, Shigeru Kuwashima, Katsunori Katagiri, Jun Suzuki, Kiyoto Shiga","doi":"10.1080/00016489.2024.2425764","DOIUrl":"10.1080/00016489.2024.2425764","url":null,"abstract":"Background: Deep neck infections (DNIs) in the cervical fascial planes can cause severe complications such as airway obstruction, mediastinitis, and sepsis.Aims/objectives: This study examines cervical abscess development, its relationship with postoperative swallowing function, and hospital stay duration.Material and methods: A retrospective case series of 55 DNI patients was divided by hospital stay (<30 days: Group A, ≥30 days: Group B) and swallowing recovery (<6 days: Group C, ≥6 days: Group D). Swallowing was assessed using FOIS; abscesses were categorized via CT and surgery.Results: Longer hospital stays (Group B) were associated with tracheostomy (p = .027) and thoracoscopic mediastinal drainage (p = .038), shorter time between symptom onset and surgery (p = .016), and abscesses in the anterior cervical (p = .007), retropharyngeal space (p = .026), and mediastinal spaces (p = .002). Dysphagia (Group D) was linked to longer hospital stays (p = .006), more abscesses in the anterior cervical (p = .049) and retropharyngeal spaces (p = .009), and higher cases of intubated feeding (p < .001). Streptococcus constellatus was more prevalent in Group D (p = .04), whereas Staphylococcus aureus was less common (p = .043).Conclusions and significance: Dysphagia is associated with abscesses in the anterior cervical and retropharyngeal spaces and higher Streptococcus constellatus prevalence, indicating delayed oral intake recovery. Thoracoscopic mediastinal drainage and shorter time to surgery were linked to prolonged hospital stays.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Narrow band imaging in oral cancer did not improve visualisation of the tumour borders: a prospective cohort study. 口腔癌窄带成像并不能改善肿瘤边界的可视化：一项前瞻性队列研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-11-12 DOI: 10.1080/00016489.2024.2418334

Olof Nilsson, Mathias von Beckerath, Johan Knutsson, Fredrik J Landström

{"title":"Narrow band imaging in oral cancer did not improve visualisation of the tumour borders: a prospective cohort study.","authors":"Olof Nilsson, Mathias von Beckerath, Johan Knutsson, Fredrik J Landström","doi":"10.1080/00016489.2024.2418334","DOIUrl":"https://doi.org/10.1080/00016489.2024.2418334","url":null,"abstract":"Background: In oral cancers, tumour borders are typically defined by white light (WL). Narrow-band imaging (NBI) is an optical endoscopic technique commonly used for the larynx and for cancers of unknown primary. However, evidence for using NBI in oral cancers is insufficient.Aims/objectives: We investigated whether NBI is a better predictor of the true mucosal tumour borders than WL in oral cancers. Additionally, we examined the agreement between NBI-based Takano intrapapillary capillary loop classifications and pathology reports.Materials and methods: In this prospective study, the tumour borders were assessed by both NBI and WL at the time of surgical resection and then compared. Pathology reports of the examined areas were used as gold standard.Results: Forty-nine participants were included. After exclusion of 15 patients due to missing data, 34 were included in analyses. In 26.5% of the assessments, the tumour borders defined by NBI were outside the borders defined by WL. However, 55.5% of these were false-positives.Conclusions and significance: The delineation of mucosal tumour borders in oral cancers by NBI was not better than that by WL in this study. Several methodological challenges may have influenced the findings of this study, similar to the limitations reported in previous studies.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-5"},"PeriodicalIF":1.2,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved intracochlear biopolymeric drug delivery system: an in vivo study. 改进的蜗内生物聚合物给药系统：体内研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-11-10 DOI: 10.1080/00016489.2024.2412719

Stefania Goncalves, Torin Thielhelm, Devon Pawley, Esperanza Bas, Emre Dikici, Sapna K Deo, Christine T Dinh, Sylvia Daunert, Fred Telischi

{"title":"Improved intracochlear biopolymeric drug delivery system: an in vivo study.","authors":"Stefania Goncalves, Torin Thielhelm, Devon Pawley, Esperanza Bas, Emre Dikici, Sapna K Deo, Christine T Dinh, Sylvia Daunert, Fred Telischi","doi":"10.1080/00016489.2024.2412719","DOIUrl":"https://doi.org/10.1080/00016489.2024.2412719","url":null,"abstract":"Background: The delivery of drugs into the inner ear is a challenging field of study due to the complex cochlear anatomy and physiology. The creation of an intracochlear device that allows for short- and long-term intracochlear delivery of the drugs with a minimal invasive technology is needed to prevent or treat conditions that can potentially prevent the development of permanent hearing loss.Aim: This study intends to test the efficacy of DXM-infused PLGA microneedles created in our laboratory in an in vivo animal model of acute ototoxic injury.Material and methods: Twenty-four male Norway Brown rats were randomized into four groups, three of which groups received an intratympanic injection of ethacrynic acid and kanamycin. Two of these groups underwent the placement of an intracochlear microneedle blended or not with dexamethasone, and two groups underwent implantation of a plain microneedle, one of without prior exposure to the ototoxic agent to confirm in vivo biocompatibility. Animals were then followed with a weekly auditory brainstem response testing until day 28 after surgical intervention.Result and conclusion: Our intracochlear device demonstrated biocompatibility and produced no hearing changes after its implantation in the control group. Inserted DXM-blended microneedles prevented hearing deterioration in those animals exposed to an ototoxic environment.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case-control study of otoconia proteins otolin-1 and otoconin-90 in patients with Meniere's disease. 梅尼埃病患者耳声蛋白 otolin-1 和 otoconin-90 的病例对照研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-11-09 DOI: 10.1080/00016489.2024.2423661

Weiwei Han, Qinfeng Wu, Yunqin Wu, Xiaoxiong Lu, Lulu Li, Kewang Zhou, Weinv Fan

{"title":"Case-control study of otoconia proteins otolin-1 and otoconin-90 in patients with Meniere's disease.","authors":"Weiwei Han, Qinfeng Wu, Yunqin Wu, Xiaoxiong Lu, Lulu Li, Kewang Zhou, Weinv Fan","doi":"10.1080/00016489.2024.2423661","DOIUrl":"https://doi.org/10.1080/00016489.2024.2423661","url":null,"abstract":"Backgrounds: Otolin-1 and otoconin-90, the main otoconia matrix protein, can pass through the labyrinth-blood barrier and are detectable in the peripheral blood. Previous studies have shown that serum levels of these proteins well reflect otolith status, but none of concerning Meniere's disease (MD).Objectives: This study aimed to evaluate the serum levels of otolin-1 and otoconin-90 in patients with MD.Material and methods: Patients with MD confirmed during an acute episode, and age- and sex-matched controls were recruited. Their demographic and clinical data were recorded. The serum levels of otolin-1 and otoconin-90 were measured and compared.Results: A total of 33 patients with MD and 176 healthy controls were recruited. In patients with MD, the median otolin-1 level was 284.96 pg/mL (interquartile range [IQR] 208.65-331.49 pg/mL) and the median otoconin-90 level was 60.50 ng/mL (IQR 40.61-85.62 ng/mL), which were significantly higher than those in the control group (p < 0.0001 and p = 0.005, respectively). Among patients with MD, serum otoconin-90 levels were correlated with the MD clinical grade (ρ = 0.487, p = 0.04), whereas serum otoconin-1 levels were not (ρ = 0.327, p = 0.063).Conclusions: Serum levels of otolin-1 and otoconin-90 may serve as biomarkers of otolith lesions in patients with MD.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-4"},"PeriodicalIF":1.2,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between preoperative factors and the pattern of longitudinal improvement in speech perception following cochlear implantation. 术前因素与人工耳蜗植入后语音感知纵向改善模式的关系。

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2023-05-01 DOI: 10.1080/00016489.2023.2200850

Jun Shinagawa, Hidekane Yoshimura, Shin-Ya Nishio, Yutaka Takumi, Shin-Ichi Usami

{"title":"The relationship between preoperative factors and the pattern of longitudinal improvement in speech perception following cochlear implantation.","authors":"Jun Shinagawa, Hidekane Yoshimura, Shin-Ya Nishio, Yutaka Takumi, Shin-Ichi Usami","doi":"10.1080/00016489.2023.2200850","DOIUrl":"https://doi.org/10.1080/00016489.2023.2200850","url":null,"abstract":"Background: Many studies have discussed the factors influencing hearing outcomes after cochlear implantation, but few have addressed improvements in speech perception for these patients over time.Objective: To investigate the relationship between preoperative factors and the pattern of longitudinal improvement in speech perception following cochlear implantation (CI).Materials and methods: This study enrolled 83 patients (96 ears) who underwent CI at Shinshu University Hospital. The patients were assessed up to 12 months after CI by a monosyllable test, and showed either delayed improvement (DI), early improvement (EI), or stable improvement (SI) when compared with their preoperative score. Eight preoperative variables were also examined for their effects on speech perception over time.Results: The DI, EI, SI groups comprised 35.4%, 43.8%, and 20.8% of all patients, respectively. Patients in the DI group were older at surgery than those in the EI and SI groups, and their onset age were also older than that in the SI group. No other preoperative variables showed significant differences across the three groups.Conclusions and significance: Our findings revealed that age at implantation and age at onset of hearing loss significantly affected the improvement pattern of speech perception. Age may be useful in predicting recovery of speech perception after CI.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"143 5","pages":"402-407"},"PeriodicalIF":1.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9530868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The French way of voice rehabilitation post total laryngectomy: current clinical practices and tendencies. 全喉切除术后法国式语音康复:临床实践及趋势。

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2023-05-01 DOI: 10.1080/00016489.2023.2206873

Dhari Al Burshaid, Morgane Corda, Serge Aho-Glele, Caroline Guigou, Mohamed Al Shehabi, Mireille Folia

{"title":"The French way of voice rehabilitation post total laryngectomy: current clinical practices and tendencies.","authors":"Dhari Al Burshaid, Morgane Corda, Serge Aho-Glele, Caroline Guigou, Mohamed Al Shehabi, Mireille Folia","doi":"10.1080/00016489.2023.2206873","DOIUrl":"https://doi.org/10.1080/00016489.2023.2206873","url":null,"abstract":"Background: Vocal rehabilitation post total laryngectomy (TL) lacks clinical guidelines, especially with the presence of multiple modalities.Objectives: To describe the tendencies of vocal rehabilitation post TL in France and compare it with other countries. We try to identify the most practiced modalities and recognize statistically significant influencing factors.Materials and methods: An electronic anonymous survey was answered by 75 ENT surgeons from France. The survey outlined the common practiced vocal rehabilitation modalities and had two versions depending on if the participant practices the tracheoesophageal speech (TES) or not.Results: 96% use TES in their practice. Single modality TES and double modality TES with esophageal speech (ES) are the two most practiced modalities. 99% agreed that there is no age limit for the TES. Single modality ES was offered 92% more when more than 10 TL were performed per year (p < .05). No influencing factors found for single modality TES or double modality TES with ES (p > .05).Conclusion: In line with tendencies from other countries, the TES is the most practiced modality of vocal rehabilitation coupled or not with the ES. TES has no age limit as per our participants. The least practiced modality is the singe modality ALS.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"143 5","pages":"440-445"},"PeriodicalIF":1.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9530583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ferroptosis inhibition shields house ear institute-organ of corti 1 cells from free fatty acids-induced inflammatory injuries. 铁下垂抑制保护耳研究所器官的corti 1细胞免受游离脂肪酸诱导的炎症损伤。

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2023-05-01 DOI: 10.1080/00016489.2023.2202688

Xuemin Chen, Yiding Yu, Ning Yu, Weiwei Guo, Qingqing Jiang, Shiming Yang

{"title":"Ferroptosis inhibition shields house ear institute-organ of corti 1 cells from free fatty acids-induced inflammatory injuries.","authors":"Xuemin Chen, Yiding Yu, Ning Yu, Weiwei Guo, Qingqing Jiang, Shiming Yang","doi":"10.1080/00016489.2023.2202688","DOIUrl":"https://doi.org/10.1080/00016489.2023.2202688","url":null,"abstract":"Background: Free fatty acids (FFAs) could induce inflammatory responses via various pathways. Ferroptosis is characterized by the accumulation of lipid peroxidation products and fatal reactive oxygen species derived from iron accumulation, which may be an upstream event in the inflammatory injuries.Objectives: To investigate the involvement of ferroptosis during the FFAs-induced pathological hair cell inflammatory injuries and its underlying mechanisms.Material and methods: We utilized House Ear Institute-Organ of Corti 1 (HEI-OC1) cell line as an in vitro model. The palmitate acid (PA) was utilized as a substitute for FFA, with cotreatment with ferroptosis inducer RSL3 and ferroptosis inhibitor Fer-1. Cell viability, lactase dehydrogenase (LDH) release, the expressions of ferroptosis-related factors such as glutathione peroxidase-4 (GPX4), solute carrier family 7 member 11 (SLC7A11), as well as toll-like receptor 4 (TLR4), ferric ion and reactive oxygen species (ROS), and partial inflammatory cytokines were measured.Results: PA treatment might induce ferroptosis in HEI-OC1 cells, manifested as decreased cell viability, upregulated LDH release, iron overload, and ROS accumulation. Several inflammatory cytokines including IL-1β, IL-6, IL-1β, IL-6, TNF-α, MCP-1, IL-13, IL-12 p40, CCL5, G-CSF, and GM-CSF were upregulated compared to the Ctr group, while GPX4 and SLC7A11 were downregulated. The expression of TLR4 in the inflammatory pathway was also upregulated. Besides, these changes were further exacerbated by RSL3 cotreatment and abolished by Fer-1 cotreatment.Conclusions and significance: Ferroptosis inhibition could alleviate the PA-induced inflammatory injuries via inactivation of TLR4 signaling pathway in HEI-OC1 cell line.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"143 5","pages":"359-369"},"PeriodicalIF":1.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9530064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of hearing loss in COVID-19 patients: a systematic review and meta-analysis. COVID-19患者听力损失患病率:系统综述和荟萃分析

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2023-05-01 DOI: 10.1080/00016489.2023.2204909

Mi Tang, Jie Wang, Qinxiu Zhang

{"title":"Prevalence of hearing loss in COVID-19 patients: a systematic review and meta-analysis.","authors":"Mi Tang, Jie Wang, Qinxiu Zhang","doi":"10.1080/00016489.2023.2204909","DOIUrl":"https://doi.org/10.1080/00016489.2023.2204909","url":null,"abstract":"Background and objective: 'Hearing loss' has been reported as a clinical atypical symptom in some COVID-19 patients. We searched and collated the existing literature for a systematic review and meta-analysis to assess the prevalence of hearing loss during the COVID-19 epidemic.Methods: An exhaustive search of the PubMed, Embase, Web of Science, China National Knowledge Infrastructure and other sources from the inception of the database until 31st December 2022. The Search terms were set to: 'COVID-19', 'SARS-CoV-2', '2019-nCoV', 'hearing impairment', 'hearing loss', 'auditory dysfunction'. The literature data meeting the inclusion criteria were extracted and analyzed. Prevalence was pooled from individual studies using a randomized effects meta-analysis.Results: A total of 22 studies were included in the final analysis, involving 14281 patients with COVID-19 infection, of which 482 patients had varying degrees of hearing loss. Our final meta-analysis demonstrated that the prevalence of hearing loss in COVID-19-positive patients was 8.2% (95%CI 5.0-12.1). Subgroup analysis of age showed that the prevalence of middle-aged and older patients aged 50-60 and over 60 years was 20.6% and 14.8%, respectively, which was significantly higher than that of patients aged 30-40 (4.9%) and 40-50 years (6.0%).Conclusion: Hearing loss is one of the clinical symptoms of COVID-19 infection, compared with other diseases, it is less likely to attract the attention of clinical experts or researchers. Raising awareness of this disease can not only enable early diagnosis and treatment of hearing loss, and improve the quality of life of patients, but also enhance our vigilance against virus transmission, which has important clinical and practical significance.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"143 5","pages":"416-422"},"PeriodicalIF":1.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9522897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Static cervico-ocular reflex in healthy humans. 健康人的静态颈眼反射。

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2023-05-01 DOI: 10.1080/00016489.2023.2201275

Tomoki Ooka, Keiji Honda, Takeshi Tsutsumi

{"title":"Static cervico-ocular reflex in healthy humans.","authors":"Tomoki Ooka, Keiji Honda, Takeshi Tsutsumi","doi":"10.1080/00016489.2023.2201275","DOIUrl":"https://doi.org/10.1080/00016489.2023.2201275","url":null,"abstract":"Background: Dynamic cervico- (COR) and vestibulo-ocular reflex (VOR) contribute to stabilise visual images in the retina. The gain in dynamic COR is small in healthy individuals but increases in patients with vestibular dysfunction. Conversely, static COR has not been directly observed in healthy individuals.Objectives: To elucidate the presence of static COR and quantify it in normal individuals in the roll plane.Methods: Eleven healthy participants were included in the study. Eye torsions were measured using video oculography to evaluate the static COR induced by lateral neck flexion during a head-upright-with-body-tilt position at 15°, 30°, and 45°. The ocular counterroll (OCR) was compared during whole-body and head tilts to assess the influence of static COR on OCR.Results: Static COR was significantly observed as eye torsion in the direction opposite to the body tilt. The head tilt OCR was significantly smaller than the whole-body tilt OCR to the right side but not to the left side.Conclusion: Static COR exists in healthy individuals and tends to show higher amplitude as neck flexion stimulation increases.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"143 5","pages":"387-391"},"PeriodicalIF":1.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9530867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0