Acta Oto-Laryngologica最新文献_第2页

Quantitative and qualitative evaluation of anti-pneumococcal specific antibodies in children with recurrent acute otitis media.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-27 DOI: 10.1080/00016489.2025.2468397

Masamitsu Kono, Eisuke Kuroda, Takuro Iyo, Nafisa Khamis Umar, Ayumi Hirayama, Saori Takeda, Daichi Murakami, Shigeto Hamaguchi, Muneki Hotomi

{"title":"Quantitative and qualitative evaluation of anti-pneumococcal specific antibodies in children with recurrent acute otitis media.","authors":"Masamitsu Kono, Eisuke Kuroda, Takuro Iyo, Nafisa Khamis Umar, Ayumi Hirayama, Saori Takeda, Daichi Murakami, Shigeto Hamaguchi, Muneki Hotomi","doi":"10.1080/00016489.2025.2468397","DOIUrl":"10.1080/00016489.2025.2468397","url":null,"abstract":"Background: Pneumococcal conjugated vaccine (PCV) has contributed to a dramatic reduction in invasive pneumococcal diseases. However, its impact upon nasopharyngeal carriage and upper respiratory tract infections is unclear.Aims/objectives: This study was aimed to evaluate the humoral immunity against Streptococcus pneumoniae in children with recurrent acute otitis media (rAOM) in the post PCV era.Materials and methods: We evaluated the humoral immunity against eight representative serotypes included in PCV13 (3, 6 A, 6B, 9 V, 14, 18 C, 19 F, and 23 F) among children with rAOM.Results: Serum total immunoglobulin levels were typically within the normal range, but there was a decrease in IgG2 in >20% of cases. Serotype-specific antibody titers were not significantly different for any serotype in the rAOM group compared with the healthy controls, except for serotype 3. Conversely, the ability of serotype-specific antibodies to induce opsonophagocytic killing was increased in the rAOM group for three serotypes (6 A, 6B, and 14). There was a positive correlation between the titer of antibodies and the opsonophagocytic killing activity in five serotypes (6 A, 6B, 9 V, 19 F, and 23 F).Conclusion and significance: Quantitative and qualitative evaluation of serotype-specific antibodies would be an important method for evaluating humoral immunity in children with rAOM.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"283-290"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The auxiliary effect of vitamin D in the treatment of chronic rhinosinusitis with nasal polyposis, a clinical trial.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-14 DOI: 10.1080/00016489.2025.2459344

Mehdi Bakhshaee, Seyed Saeed Hosseini, Abolfazl Zanghaei, Mona Najaf Najafi, Fatemeh Bavi, Imaneh Roshanzamir

{"title":"The auxiliary effect of vitamin D in the treatment of chronic rhinosinusitis with nasal polyposis, a clinical trial.","authors":"Mehdi Bakhshaee, Seyed Saeed Hosseini, Abolfazl Zanghaei, Mona Najaf Najafi, Fatemeh Bavi, Imaneh Roshanzamir","doi":"10.1080/00016489.2025.2459344","DOIUrl":"10.1080/00016489.2025.2459344","url":null,"abstract":"Background: Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) is a prevalent chronic inflammatory disorder of the nasal cavity and paranasal sinus with benign polypoid masses. Recent evidence highlights the immunomodulatory role of Vitamin D (Vit D) in mitigating inflammation associated with CRSwNP.Aims: The aim of this study is to examine the effect of Vit D on the improvement of CRSwNP.Material and methods: This randomized, double-blind clinical trial was conducted on 59 patients with CRSwNP. All patients with Vit D deficiency (25OH Vit D level < 20 ng/mL) or insufficiency (<30 ng/mL) underwent endoscopic sinus surgery (ESS). The rate of changes in the patients' symptoms were recorded before and 8 weeks after the surgery.Result: All patients showed a better postsurgical improvement in terms of Visual Analogue Scale(VAS), Lund-Kennedy (LK), and Questionnaire (SNOT-22) scores. The Vit D supplement group showed better postsurgical improvement in comparison to placebo in terms of VAS and LK scores (p = 0.02, p = 0.03 respectively).Conclusions and significance: The administration of Vit D after ESS is relatively effective in the improvement of CRSwNP symptoms. This finding highlights the possibility of developing an efficient, safe, and cost-effective therapy for patients with CRSwNP.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"313-318"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifaceted evaluation of the effects of smoking on Eustachian tube function.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-22 DOI: 10.1080/00016489.2025.2468911

Aykut Yankuncu, İrem Bozkurt Karaçuha, Sema Zer Toros, Çiğdem Tepe Karaca

{"title":"Multifaceted evaluation of the effects of smoking on Eustachian tube function.","authors":"Aykut Yankuncu, İrem Bozkurt Karaçuha, Sema Zer Toros, Çiğdem Tepe Karaca","doi":"10.1080/00016489.2025.2468911","DOIUrl":"10.1080/00016489.2025.2468911","url":null,"abstract":"Background: The Eustachian tube is essential for middle ear health, ensuring pressure equalization, ventilation, and protection from pathogens. Smoking has been linked to altered Eustachian tube function, affecting mucociliary activity and middle ear ventilation.Aims/objectives: This study evaluates smoking's impact on Eustachian tube function using tympanometry, nasal mucociliary clearance testing, and the Eustachian Tube Dysfunction Questionnaire.Material and methods: Healthy adults aged 20-50 years with intact tympanic membranes, no upper respiratory infections, or nasal pathologies were included. Participants were divided into smokers (subgrouped by smoking history: 5-10, 10-20, and >20 pack-years) and non-smokers. Tympanometry, mucociliary clearance testing, and the questionnaire were administered.Results: Among 276 participants, significant differences in questionnaire scores, compliance, middle ear pressure, and mucociliary clearance times were observed between groups (p < 0.01, p = 0.02, p < 0.001, and p = 0.009, respectively). Ipsilateral acoustic reflexes differed significantly between groups (p < 0.005 and p = 0.049). Mucociliary clearance times were notably prolonged in the >20 pack-years group compared to the 5-10 pack-years group (p = 0.012).Conclusions and significance: Smoking adversely affects Eustachian tube function, as evidenced by tympanometric, mucociliary, and questionnaire assessments.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"303-307"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are polydioxanone plates combined with temporoparietal fascia the best technique for repair of nasal septal perforation?

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-11 DOI: 10.1080/00016489.2025.2461652

Patrícia Silva Sousa, João Viana Pinto, Gil Coutinho, Diogo Abreu Pereira, Carla Pinto Moura, Tiago Órfão

{"title":"Are polydioxanone plates combined with temporoparietal fascia the best technique for repair of nasal septal perforation?","authors":"Patrícia Silva Sousa, João Viana Pinto, Gil Coutinho, Diogo Abreu Pereira, Carla Pinto Moura, Tiago Órfão","doi":"10.1080/00016489.2025.2461652","DOIUrl":"10.1080/00016489.2025.2461652","url":null,"abstract":"Background: The repair of nasal septal perforations is challenging. Interposition of polydioxanone (PDS) plates combined with fascia graft have been described in the literature with high success rates.Aims: This study aims to present a case series on the closure of nasal septal perforation using this technique and to evaluate its outcomes.Material and methods: Retrospective evaluation of patients who underwent surgical repair of nasal septal perforations with interposition fascia graft and PDS plates from 2020 to 2023.Results: Nine patients were evaluated, 66.7% were male and the mean age was 40.7 years. The perforation size ranged from 0.9 to 4.5 cm (largest diameter). All procedures were performed by an open approach and all patients received interposition grafts of PDS plates - eight cases combined with a temporoparietal fascia graft and one combined with a rectus abdominis muscle fascia graft. Eight patients (88.9%) achieved complete closure of the perforation. No other complications were reported.Conclusions and significance: Interposition temporoparietal fascia graft combined with PDS plates could be a highly effective technique, demonstrating good functional and anatomic outcomes with low morbidity at the donor site. This composite can be applied to small and large perforations as surgical success does not appear to be affected by the defect size.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"324-328"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translation, validation, and psychometric evaluation of the Italian version of the facial clinimetric evaluation (FaCE) scale for patients with peripheral facial palsy.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-13 DOI: 10.1080/00016489.2024.2447039

Federica Nizzoli, Elisabetta Losi, Maria Vittoria Bergamini, Marco Bonali, Matteo Alicandri-Ciufelli, Daniele Marchioni, Gian Maria Galeazzi, Luca Pingani, Elena Reggiani

{"title":"Translation, validation, and psychometric evaluation of the Italian version of the facial clinimetric evaluation (FaCE) scale for patients with peripheral facial palsy.","authors":"Federica Nizzoli, Elisabetta Losi, Maria Vittoria Bergamini, Marco Bonali, Matteo Alicandri-Ciufelli, Daniele Marchioni, Gian Maria Galeazzi, Luca Pingani, Elena Reggiani","doi":"10.1080/00016489.2024.2447039","DOIUrl":"10.1080/00016489.2024.2447039","url":null,"abstract":"Background: In the management of patients with peripheral facial palsy, it is essential to have tools that allow patients to tell what their facial disabilities are.Objective: This study aimed to translate and validate the FaCE scale into Italian (I-FaCE).Material and methods: The FaCE scale was translated into Italian using a three-stage process. The draft was reviewed for comprehensibility by SLTs and revised accordingly. The beta version of I-FaCE was administered to 200 patients. Internal consistency was measured using McDonald's omega, while test-retest reliability was assessed with a fifteen-day interval between administrations. Confirmatory factor analysis (CFA) was performed to evaluate construct validity. Concurrent validity was tested by correlating I-FaCE scores with the House-Brackmann Scale, Sunnybrook Scale, and FDI Scale.Results: The I-FaCE demonstrated excellent internal consistency (McDonald's omega = 0.87) and strong test-retest reliability. CFA indicated a good model fit, with indices such as CFI (0.94), TLI (0.91), RMSEA (0.07), and RMSR (0.06). Concurrent validity showed significant correlations between I-FaCE and other grading systems.Conclusion and significance: I-FaCE is a valid and reliable tool to assess the impact of facial dysfunction on quality of life. Its adoption will facilitate better patient care and enable meaningful comparisons with international data.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"355-361"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transoral 980 nm and 1470 nm dual-wavelength fiber laser combined with flexible endoscopes for porcine anterior commissure resection of vocal cord.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-03-01 DOI: 10.1080/00016489.2025.2467916

Xijun Lin, Ping Han, Peiliang Lin, Jingyi Wang, Xiangwei Kong, Xiaoming Huang, Faya Liang

{"title":"Transoral 980 nm and 1470 nm dual-wavelength fiber laser combined with flexible endoscopes for porcine anterior commissure resection of vocal cord.","authors":"Xijun Lin, Ping Han, Peiliang Lin, Jingyi Wang, Xiangwei Kong, Xiaoming Huang, Faya Liang","doi":"10.1080/00016489.2025.2467916","DOIUrl":"https://doi.org/10.1080/00016489.2025.2467916","url":null,"abstract":"Background: Early-stage glottic cancer with anterior commissure involvement presents challenges in exposure and treatment, affecting tumor recurrence and surgical outcomes.Objective: This study investigated the feasibility of transoral 980 nm and 1470 nm dual-wavelength fiber laser combined with flexible endoscopes for porcine anterior commissure resection.Material and methods: Five healthy adult pigs were used as experimental subjects. The procedure involved exposing the anterior commissure using a flxible laryngoscope and resecting it using the dual-wavelength laser. The assessment focused on the ease of exposure and resection.Results: In all five presented pigs, the vocal folds' anterior commissure was well exposed. Furthermore, the anterior commissure of the pigs could be smoothly resected, with the resection range reaching the thyroid cartilage plate, and there were no difficulties in resection due to obstruction by the laryngoscope. No intraoperative or postoperative complications occurred.Conclusions and significance: The study demonstrates the feasibility and safety of using a flxible laryngoscope combined with a dual-wavelength laser for porcine anterior commissure resection. This approach offers potential as a method for laser surgery in human laryngeal diseases, particularly glottic laryngeal cancer involving the anterior commissure.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"145 4","pages":"334-339"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute acoustic traumas caused by large-caliber weapons and explosions among conscripts in the Finnish Defence Forces - a population-based survey.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-21 DOI: 10.1080/00016489.2025.2467922

Markku Toivonen, Rauno Pääkkönen, Riina Niemensivu, Antti A Aarnisalo, Antti A Mäkitie

{"title":"Acute acoustic traumas caused by large-caliber weapons and explosions among conscripts in the Finnish Defence Forces - a population-based survey.","authors":"Markku Toivonen, Rauno Pääkkönen, Riina Niemensivu, Antti A Aarnisalo, Antti A Mäkitie","doi":"10.1080/00016489.2025.2467922","DOIUrl":"10.1080/00016489.2025.2467922","url":null,"abstract":"Background: Conscripts have a risk for an acute acoustic trauma (AAT) due to exposure to large-caliber weapons or explosions despite the much tighter safety precautions than those for rifle-caliber weapons.Aims: We aimed to investigate the population-based frequency of AATs after exposure to such noise sources during conscript training in the Finnish Defence Forces (FDF), and to evaluate their possible causes.Materials and methods: We collected all registered AAT incidents from the FDF over the available periods 1997-2003 and 2008-2010.Results: The likelihood of having an AAT from heavy weapon or explosion noise was 0.07%, and the most common noise sources were cannons, bazookas and mortars.Conclusions and significance: There is a constant need to survey, educate and train personnel regarding risks of noise at military exercises to prevent AATs. This study adds to the existing knowledge on the risk of hearing loss resulting from AAT in military settings.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"299-302"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-01-24 DOI: 10.1080/00016489.2025.2458894

引用次数: 0

Adaptive changes in human inferior turbinates between humid and dry climates.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-08 DOI: 10.1080/00016489.2025.2460605

Volkan Güngör, Yonca Çoluk, Tümay Bekçi, Orhan Tunç, R Orkun Önder, Devrim Bektaş

{"title":"Adaptive changes in human inferior turbinates between humid and dry climates.","authors":"Volkan Güngör, Yonca Çoluk, Tümay Bekçi, Orhan Tunç, R Orkun Önder, Devrim Bektaş","doi":"10.1080/00016489.2025.2460605","DOIUrl":"10.1080/00016489.2025.2460605","url":null,"abstract":"Background: Currently, there is limited knowledge regarding the effects of climate on the lower turbinate morphology.Objectives: This study evaluated the existence of humidity-related climatically adaptive changes in inferior turbinate.Methods: Previously taken computed tomography images of the paranasal region were evaluated belonging to a total of 100 patients from two different climates (50 patients each from humid climate and from dry climate). The width, length and height of the lower turbinate, the breadth, length and height of the internal nasal passage, height of the inferior airway, breadth of common and inferior meatus were compared.Results: The group from dry climate has narrower internal nasal passage breadth (p = .010) with wider inferior meatus width (p = .031). No dimensional difference in the lower turbinates was observed between the two climatic groups. These two findings indicate a more lateralized turbinates in the humid group as opposed to more centralized turbinates in the dry group.Conclusions: Humidity has an effect as a climatic factor on turbinate positioning in the nasal fossa and contribute to an overall pattern of ecogeographic variation of nose. It may be useful to review surgical interventions to the inferior turbinate in the light of this information.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"319-323"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of saliva pepsin concentration on subjective severity of seasonal allergic rhinitis.

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-01 Epub Date: 2025-02-11 DOI: 10.1080/00016489.2025.2460610

Haijing Sui, Zhu Luo, Xuehan Zhang, Junbo Zhang, Zhen Zhen, Ting Ding

{"title":"The influence of saliva pepsin concentration on subjective severity of seasonal allergic rhinitis.","authors":"Haijing Sui, Zhu Luo, Xuehan Zhang, Junbo Zhang, Zhen Zhen, Ting Ding","doi":"10.1080/00016489.2025.2460610","DOIUrl":"10.1080/00016489.2025.2460610","url":null,"abstract":"Backgrounds: Some studies believe that there is a correlation between larygopharyngeal reflux disease (LPRD) and allergic rhinitis (AR). Salivary pepsin concentration (SPC) test is a gradually accepted objective examination method for LPRD in recent years.Objectives: To investigate the impact of coexisting LPRD on subjective severity of seasonal AR and the potential role of pepsin.Material and methods: Adult patients with seasonal AR were prospectively enrolled. Subjective severity of AR was assessed using the Total Nasal Symptom Score (TNSS) and visual analog scale (VAS). Potential LPRD was assessed using the Reflux Symptom Index (RSI) and SPC measurements.Results: No significant correlation was found between the RSI value and the TNSS and VAS values (both p > .05). In contrast, the SPC value was found to be significantly associated with both of TNSS and VAS values (p < .05). Among the symptoms included in the TNSS, the SPC value was significantly and positively associated with nasal congestion and runny nose (both p < .05), but not with sneezing and nasal itching (both p > .05).Conclusions and significance: Coexisting LPRD may aggravates seasonal AR symptoms. SPC could be used to examine whether AR patients have combined LPRD and to determine the necessity of anti-reflux treatment.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"329-333"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0