Acta Oto-Laryngologica最新文献_第2页

A modified hook-assisted transmuscular technique to optimise cochlear implant coupling in patients with thick scalp flaps. 改良的钩辅助经肌技术优化厚头皮皮瓣患者耳蜗植入耦合。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-12 DOI: 10.1080/00016489.2026.2684640

Yang Zhang, Pengfei Guan, Harry Hoang, Jingfang Wu, Yunfeng Wang

{"title":"A modified hook-assisted transmuscular technique to optimise cochlear implant coupling in patients with thick scalp flaps.","authors":"Yang Zhang, Pengfei Guan, Harry Hoang, Jingfang Wu, Yunfeng Wang","doi":"10.1080/00016489.2026.2684640","DOIUrl":"10.1080/00016489.2026.2684640","url":null,"abstract":"Background: Achieving adequate coupling between the internal and external components of a cochlear implant is essential for optimal device performance and depends in part on scalp thickness.Aims/objectives: Suboptimal cochlear implant coupling may occur in patients with increased scalp thickness, leading to impaired magnetic retention and signal transmission. This study describes a modified hook-assisted transmuscular technique designed to address this issue while preserving soft tissue integrity.Material and methods: This retrospective single-centre case series included adult patients undergoing cochlear implantation with scalp thickness >7 mm. The technique involves two parallel muscle incisions and the use of a custom-designed hook to elevate the temporalis muscle under direct visualisation, allowing controlled implant placement without the need for skin flap thinning.Results: The method was applied in 15 adult patients with a follow-up period of 1 to 6 months. Mean scalp thickness was reduced from 10.7 mm to 4.3 mm. No cases of flap necrosis or infection were observed. Operative time was comparable to conventional procedures, and no patients required revision surgery or high-strength magnets during follow-up.Conclusions and significance: This technique appears to be a feasible and practical option for improving cochlear implant coupling in patients with thick scalp flaps. Further studies are required to assess long-term outcomes.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1271-1274"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148222440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral diadochokinesis as a candidate bedside indicator for swallowing dysfunction assessed by videoendoscopic evaluation using the Hyodo score: retrospective cross-sectional study. 使用Hyodo评分通过内镜评估评估口服吞咽运动作为吞咽功能障碍的候选床边指标：回顾性横断面研究

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-25 DOI: 10.1080/00016489.2026.2688876

Katsuya Okuda, Ryo Ueda, Tetsuya Kinoshita, Ryosuke Ito, Mayumi Nakaie, Tatsuya Shiga, Mai Miyamoto, Kazuya Mizobata, Fumiya Kitamura, Kohei Kawabata, Chishin Yohda, Takuma Okada, Hideki Sakatani, Shunji Tamagawa, Muneki Hotomi, Masamitsu Kono

{"title":"Oral diadochokinesis as a candidate bedside indicator for swallowing dysfunction assessed by videoendoscopic evaluation using the Hyodo score: retrospective cross-sectional study.","authors":"Katsuya Okuda, Ryo Ueda, Tetsuya Kinoshita, Ryosuke Ito, Mayumi Nakaie, Tatsuya Shiga, Mai Miyamoto, Kazuya Mizobata, Fumiya Kitamura, Kohei Kawabata, Chishin Yohda, Takuma Okada, Hideki Sakatani, Shunji Tamagawa, Muneki Hotomi, Masamitsu Kono","doi":"10.1080/00016489.2026.2688876","DOIUrl":"10.1080/00016489.2026.2688876","url":null,"abstract":"Background: Early identification of swallowing dysfunction is important in aging populations because dysphagia is associated with malnutrition, aspiration pneumonia, and reduced quality of life. Oral diadochokinesis (ODK) is a simple, noninvasive test of oral motor function, however, its relationship with swallowing dysfunction remains unclear.Aims/objectives: To investigate associations between ODK and swallowing dysfunction assessed by videoendoscopic examination of swallowing (VE) using the Hyodo score.Methods: This retrospective study included 42 patients who underwent VE for suspected dysphagia. Swallowing function was assessed using the Hyodo score, and patients were classified into two groups (≤4 and ≥5). ODK was evaluated by measuring repetition rates of /pa/, /ta/, and /ka/. Group comparisons, correlation analyses, ROC curve analyses, and multivariable logistic regression analyses were performed.Results: ODK values were significantly lower in patients with Hyodo scores ≥5 (p < 0.0001). The Hyodo score showed significant negative correlations with ODK /pa/ (r= -0.6632), /ta/ (r= -0.5988), and /ka/ (r= -0.6274) (p < 0.0001). ROC analysis demonstrated good discrimination (AUCs: 0.8535, 0.8444, and 0.8352). Lower values of ODK were independently associated with swallowing dysfunction.Conclusions: Reduced ODK performance was associated with swallowing dysfunction assessed by VE.Significance: ODK may serve as a simple bedside indicator to identify patients requiring further instrumental evaluation.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1304-1313"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The efficacy of modified sternocleidomastoid muscle flap in preventing sialocele and salivary fistula following partial superficial parotidectomy. 改良胸锁乳突肌瓣预防腮腺部分浅表性切除术后涎腺囊肿和唾液瘘的疗效。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-02 DOI: 10.1080/00016489.2026.2678463

Ayca Arslan, İbrahim Emre Kilic, Arzubetul Duran, Felat Toprak, Bayram Baris Buyuk, Tuncay Tunccan, Caner Kilic

{"title":"The efficacy of modified sternocleidomastoid muscle flap in preventing sialocele and salivary fistula following partial superficial parotidectomy.","authors":"Ayca Arslan, İbrahim Emre Kilic, Arzubetul Duran, Felat Toprak, Bayram Baris Buyuk, Tuncay Tunccan, Caner Kilic","doi":"10.1080/00016489.2026.2678463","DOIUrl":"10.1080/00016489.2026.2678463","url":null,"abstract":"Background: Sialocele and salivary fistula are well-established early postoperative complications following partial superficial parotidectomy (PSP).Aims: This study aims to evaluate the effectiveness of the modified sternocleidomastoid muscle (MSCM) flap performed prophylactically following PSP to prevent sialocele and salivary fistula formation.Methods: This retrospective cohort study included 230 patients who underwent PSP for benign parotid neoplasia at a tertiary referral center between 2012 and 2024. The primary independent variable was the surgical management (MSCM flap vs. no flap following PSP), while the primary outcome variable was the development of a sialocele or a subsequent salivary fistula. The chi-squared (χ2) test was utilized for group comparisons, while Fisher's exact test was employed when cell counts were less than 5.Results: The study cohort comprised 230 patients with a mean age of 51 ± 19, and 51.3% were male. Sialoceles occured in 2 (10%) patients in the MSCM flap group compared to 76 (36.2%) in the control group (p = 0.024). Notably, no salivary fistulas (0%) developed in the MSCM flap group, whereas 23 (10.9%) cases occurred in the control group (p = 0.05).Conclusion: The MSCM flap technique is an effective and reliable surgical method for preventing the development of both sialocele and salivary fistula following PSP.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1206-1212"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148147977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of microscopic and transcanal endoscopic ear surgery for Naim stage I-III external auditory canal cholesteatoma. 经鼻内镜与镜下耳部手术治疗Naim期I-III期外耳道胆脂瘤的比较。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-08-06 DOI: 10.1080/00016489.2026.2681683

Qiulin Yuan, Yu Du, Yuqing Zhou, Tuanfang Yin, Jihao Ren, Wei Liu

{"title":"Comparison of microscopic and transcanal endoscopic ear surgery for Naim stage I-III external auditory canal cholesteatoma.","authors":"Qiulin Yuan, Yu Du, Yuqing Zhou, Tuanfang Yin, Jihao Ren, Wei Liu","doi":"10.1080/00016489.2026.2681683","DOIUrl":"10.1080/00016489.2026.2681683","url":null,"abstract":"Background: Although both microscopic and endoscopic techniques are used in external auditory canal cholesteatoma surgery, their comparative efficacy remains unclear.Objective: To compare the outcomes of microscopic and transcanal endoscopic treatments for Naim stage I-III external auditory canal cholesteatoma.Methods: A retrospective analysis was conducted on patients diagnosed with Naim stage I-III external auditory canal cholesteatoma (EACC) between November 2015 and November 2025. Clinical characteristics were compared between the transcanal endoscopic ear surgery (TEES) group and microscopic ear surgery (MES) group.Result: TEES had shorter operative time (46.45 ± 25.61 vs. 65.24 ± 44.98 min) and time to complete epithelialization (28.3 ± 4.7 vs. 45.8 ± 3.2 days) than MES (both p < 0.05). No postoperative cholesteatoma recurrence or EAC stenosis/atresia occurred in TEES. Conversely, MES complications included isolated recurrence (n = 2, 4.4%), isolated EAC stenosis/atresia (n = 1, 2.2%), concurrent recurrence and stenosis (n = 3, 6.7%), and transient facial paralysis (n = 1, 2.2%).Conclusion: Surgical management of EACC should be tailored to the extent of the lesion. For Naim stage I-III cases, TEES represents a safe and effective minimally invasive modality.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1238-1244"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of mismatch response-based programming on hearing and speech performances in cochlear implanted children: a follow-up study. 基于错配反应的编程对人工耳蜗植入儿童听力和语言表现的影响：一项随访研究。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-25 DOI: 10.1080/00016489.2026.2688877

Min Shen, Yan Miao, Yang Zhang, Liyan Wang, Wei Liang

{"title":"The effects of mismatch response-based programming on hearing and speech performances in cochlear implanted children: a follow-up study.","authors":"Min Shen, Yan Miao, Yang Zhang, Liyan Wang, Wei Liang","doi":"10.1080/00016489.2026.2688877","DOIUrl":"10.1080/00016489.2026.2688877","url":null,"abstract":"Background: It remains unclear whether the auditory mismatch response (MMR) can assist cochlear implants (CI) programming in children with CIs.Objective: To explore the effects of MMR-based programming on hearing and speech abilities in cochlear implanted (CI) children.Material and methods: Twenty-two children were initially recruited, and 20 (14 boys, 6 girls) completed the study. The children received MMR-guided CI programming. Conventional subjective assessments were performed before programming (Pre), within one week after programming (W1), and three months after programming (M3).Results: First, the scores of the MMR test, CAP, SIR, MUSS, consonants recognition, vowels recognition, and lexical tones recognition at W1 and M3 were significantly higher than those at Pre (p < 0.05). Second, MMR scores are not only positively correlated with certain hearing and speech performances at the same time point, but also with those at subsequent time points (p < 0.05).Conclusions and significance: The MMR detection rate, as well as hearing and speech performances, consistently improved following MMR-based CI programming in CI children. Moreover, the effects remained stable over the 3-month follow-up period. MMR-based programming may serve as a new method of precision CI fitting.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1314-1325"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cervical abscess foci drainage in patients with oropharyngeal tularemia: clinical experience and treatment outcomes. 口咽菌血症患者宫颈脓肿病灶引流：临床经验及治疗效果。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-17 DOI: 10.1080/00016489.2026.2681695

Ahmet Aksoy, Yavuz Tacyıldız

{"title":"Cervical abscess foci drainage in patients with oropharyngeal tularemia: clinical experience and treatment outcomes.","authors":"Ahmet Aksoy, Yavuz Tacyıldız","doi":"10.1080/00016489.2026.2681695","DOIUrl":"10.1080/00016489.2026.2681695","url":null,"abstract":"Background: Oropharyngeal tularemia often presents with suppurative cervical lymphadenopathy, in which necrotic tissue can hinder antimicrobial penetration. Despite established medical protocols, standardized criteria for surgical timing and associated factors of disease severity remain unclear.Objectives: We aimed to describe the clinical features of tularemia-related cervical abscesses, assess treatment responses, and identify factors predicting hospitalization.Materials and methods: We performed a retrospective study of 89 patients (microagglutination titer ≥1:160) between November 2023 and October 2024. Data included demographics, imaging, and outcomes, with ROC analysis used to identify prognostic indicators.Results: The mean age was 41.9 ± 18.0 years; 61.8% of patients were female. Oropharyngeal tularemia predominated, with cervical swelling present in 84.3% of cases. Hospitalization was required for 50.6% of patients (median stay: 8 days). Due to suboptimal antibiotic response, 48.3% underwent surgical intervention. Male sex and a WBC count >7.9 × 109/L were independently associated with hospitalization. Inpatients showed higher leukocyte indices and a greater need for surgery. Among patients who underwent debridement or tissue sampling, necrotizing granulomatous inflammation may indicate more severe disease retrospectively.Conclusions and significance: Cervical suppuration is a major cause of morbidity in oropharyngeal tularemia. Although medical therapy remains the primary treatment, timely surgical intervention is crucial in refractory cases to improve outcomes in endemic regions.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1185-1196"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148269839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes and quantitative comparison of mucosal repair using skin grafting versus polyglycolic acid sheet application for cT1-2 oral cancer defect. 植皮黏膜修复与聚乙醇酸片修复口腔癌cT1-2缺损的远期疗效及定量比较

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-26 DOI: 10.1080/00016489.2026.2682521

Younghac Kim, Eun-Hye Kim, Han-Sin Jeong

{"title":"Long-term outcomes and quantitative comparison of mucosal repair using skin grafting versus polyglycolic acid sheet application for cT1-2 oral cancer defect.","authors":"Younghac Kim, Eun-Hye Kim, Han-Sin Jeong","doi":"10.1080/00016489.2026.2682521","DOIUrl":"10.1080/00016489.2026.2682521","url":null,"abstract":"Background: Skin grafting and polyglycolic acid (PGA) sheet application are two established mucosal repair techniques for early-stage oral cancer defects, yet quantitative long-term comparative data are lacking.Aims and objectives: To compare long-term wound contracture and postoperative complications of two methods for cT1-2 oral cancer mucosal defects.Material and methods: In this retrospective cohort study, 53 patients who underwent mucosal repair with skin graft (n = 25) or PGA sheet (n = 28) were followed for long-term wound shrinkage (median, 40.0 months), graft failure/necrosis, postoperative bleeding, and tongue tethering.Results: Wound area decreased to 25.0% (interquartile range [IQR], 15.5-36.3) of the initial defect in the skin graft group versus 12.6% (IQR, 9.2-17.9) in the PGA sheet group (p = 0.0019). Multivariable analysis identified PGA sheet application (p = 0.0015) and adjuvant radiation (p = 0.0056) as independent predictors of greater wound shrinkage. Postoperative bleeding (21.4% vs. 8.0%) and tongue tethering (32.1% vs. 8.0%, p = 0.043) were more frequent in the PGA sheet group.Conclusions and significance: Skin grafting offers superior long-term dimensional stability and fewer functional complications for cT1-2 oral cancer defects. PGA sheets may be preferred when operative time or donor-site morbidity is a priority, providing practical guidance for reconstructive planning.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1245-1252"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of asymmetric hearing loss in Korean adults. 韩国成年人不对称听力损失的患病率。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-12 DOI: 10.1080/00016489.2026.2685217

Jaeman Park, Dongjun Woo, Jiyeon Park, Gi Jung Im, Jae-Jun Song, Sung-Won Chae

{"title":"Prevalence of asymmetric hearing loss in Korean adults.","authors":"Jaeman Park, Dongjun Woo, Jiyeon Park, Gi Jung Im, Jae-Jun Song, Sung-Won Chae","doi":"10.1080/00016489.2026.2685217","DOIUrl":"10.1080/00016489.2026.2685217","url":null,"abstract":"Background: Representative data on asymmetric hearing loss (AHL) in Korea remain limited.Aims/objectives: To estimate AHL prevalence among Korean adults aged ≥40 years and characterize age-standardized prevalence, frequency-specific asymmetry, laterality, and interaural difference (IAD) distribution.Material and methods: Data from the 2022-2023 Korea National Health and Nutrition Examination Survey were analyzed. Adults aged ≥40 years with complete bilateral pure-tone audiometry and type A or type C tympanograms were included. AHL was defined as an absolute IAD ≥15 dB HL in the four-frequency pure-tone average. Weighted analyses accounted for the complex sampling design.Results: Among 6,574 participants, 447 had AHL. Weighted prevalence was 6.5% (95% confidence interval [CI], 5.9-7.2%), and directly age-standardized prevalence was 6.0% (approximate 95% CI, 5.3-6.6%). Prevalence increased from 3.2% at 40-49 years to 11.9% at ≥80 years. Older age and male sex were independently associated with AHL; occupational noise exposure was not. Frequency-specific asymmetry was most common at 4 kHz. Among AHL cases, left-sided AHL predominated, and IADs were concentrated near the lower end of the diagnostic range.Conclusions and significance: AHL increased with age and showed high-frequency and left-sided predominance. These findings provide population-based reference data and support cautious interpretation of criterion-defined AHL.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1275-1282"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148222411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy evaluation of intracervical lymph node immunotherapy (ICLIT) in children with allergic rhinitis and allergic rhinitis complicated with asthma. 颈内淋巴结免疫疗法（ICLIT）治疗儿童变应性鼻炎及变应性鼻炎合并哮喘的疗效评价

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-11 DOI: 10.1080/00016489.2026.2679182

Kai Wang, Siyu Tian, Yang Qin, Chuhao Li, Feng Li, Chengzhi Li, Jianbo Shi

{"title":"Efficacy evaluation of intracervical lymph node immunotherapy (ICLIT) in children with allergic rhinitis and allergic rhinitis complicated with asthma.","authors":"Kai Wang, Siyu Tian, Yang Qin, Chuhao Li, Feng Li, Chengzhi Li, Jianbo Shi","doi":"10.1080/00016489.2026.2679182","DOIUrl":"10.1080/00016489.2026.2679182","url":null,"abstract":"Background: Intracervical lymph node immunotherapy (ICLIT) has demonstrated favorable short-term efficacy and safety in children with allergic rhinitis (AR). However, its efficacy in children with AR complicated by asthma (AR+AA) remain studied.Aims/objectives: To evaluate the validity of ICLIT in children with AR+AA.Material and methods: Thirty children were enrolled, with 15 in AR group and 15 in AR+AA group. All patients received ICLIT. Total nasal symptom score (TNSS), total ocular symptom score (TOSS), and rhinoconjunctivitis quality of life questionnaire (RQLQ) were assessed at baseline and 3, 6 and 12 months post-treatment. The AR+AA group additionally completed the asthma control questionnaire (ACQ-6) and pediatric asthma quality of life questionnaire (PAQLQ). IgE were measured too.Results: After 12 months of treatment, both groups showed significant improvements from baseline in TNSS, TOSS, and RQLQ (all p < 0.05). However, the magnitude of improvement did not differ significantly between groups (all p > 0.05). In the AR+AA group, ACQ-6 scores decreased from 1.81 ± 1.32 at baseline to 0.51 ± 1.21 (p < 0.001). Serum total IgE and dust mite-specific IgE levels significantly decreased from baseline in both groups (p < 0.05).Conclusions and significance: ICLIT effectively improves symptoms and quality of life in children with both isolated AR and AR+AA.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1221-1231"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148222404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The minimal clinically important difference for the Sniffin' Sticks Identification Test-16 in patients with chronic rhinosinusitis with nasal polyps treated with biologics. 在使用生物制剂治疗的慢性鼻窦炎鼻息肉患者中，嗅探棒识别测试-16的最小临床重要差异。

IF 1.3 4区医学

Acta Oto-Laryngologica Pub Date : 2026-10-01 Epub Date: 2026-06-21 DOI: 10.1080/00016489.2026.2683697

Christian K Pedersen, Simon Høj, Marie Høxbro, Anne-Sophie Homøe, Susanne I Scott, Kasper Aanæs, Tonny S Petersen, Christian von Buchwald, Vibeke Backer

{"title":"The minimal clinically important difference for the Sniffin' Sticks Identification Test-16 in patients with chronic rhinosinusitis with nasal polyps treated with biologics.","authors":"Christian K Pedersen, Simon Høj, Marie Høxbro, Anne-Sophie Homøe, Susanne I Scott, Kasper Aanæs, Tonny S Petersen, Christian von Buchwald, Vibeke Backer","doi":"10.1080/00016489.2026.2683697","DOIUrl":"10.1080/00016489.2026.2683697","url":null,"abstract":"Background: The Minimal Clinically Important Difference (MCID) reflects the smallest change in a test score perceived as relevant by the patient. MCIDs vary according to disease and clinical context. The Sniffin' Sticks Identification Test 16 (SSIT-16) is a commonly used smell assessment tool, but its MCID in severe chronic rhinosinusitis with nasal polyps (CRSwNP) is unknown.Objective: To determine the MCID of SSIT-16 in severe CRSwNP treated with biologics.Materials and methods: We analysed change scores from baseline to week 24 in 313 patients. The MCID was estimated using anchor-based and distribution-based methods. Anchors included a visual analogue scale (VAS) for smell, the rhinologic domain of SNOT-22, and the smell/taste item of SNOT-22. Distribution-based analyses included half a standard deviation of baseline SSIT-16 scores, the standard error of measurement (SEM), and the individual-level smallest detectable change.Results: The smell VAS performed best and was therefore chosen as the primary anchor. The optimal ΔSSIT-16 cut-off, balancing sensitivity (78%) and specificity (84%), was 3.5 points. This estimate was supported by distribution-based, sensitivity, and subgroup analyses.Conclusion and significance: An improvement of approximately 3.5 SSIT-16 points appears to reflect clinically meaningful change in biologically treated patients with severe CRSwNP and may serve as a pragmatic threshold for interpreting olfactory outcomes.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1263-1270"},"PeriodicalIF":1.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148292954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0