{"title":"Revision of the Turkish Khalfa Hyperacusis Questionnaire: a boosted tool for the tinnitus population.","authors":"Nazife Öztürk Özdeş, Gizem Kır, Suna Tokgöz-Yılmaz","doi":"10.1080/00016489.2025.2485438","DOIUrl":"10.1080/00016489.2025.2485438","url":null,"abstract":"<p><strong>Background: </strong>Due to low factor loadings and problems with construct validity of the current version of the Turkish Khalfa Hyperacusis Questionnaire, there is a need for a revision that can more accurately assess hyperacusis in individuals with tinnitus.</p><p><strong>Objective: </strong>The main aim of this study was to re-evaluate the Khalfa Hyperacusis Questionnaire for individuals with tinnitus and to analyze its reliability and validity.</p><p><strong>Materials and methods: </strong>The new version of Khalfa Hyperacusis Questionnaire (HQ-R), consisting of 12 items, was tested on 269 participants with tinnitus and the suitability of the two-factor structure was evaluated by Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA).</p><p><strong>Results: </strong>EFA revealed that the scale explained 60.247% of the total variability and the factor loadings were strong. It was determined that the CFA model provided an excellent fit. The CA value of the instrument was found to be 0.908 and a high level of reliability was obtained. The cut-off score was 14 and this value was used to accurately classify hyperacusis.</p><p><strong>Conclusion: </strong>The HQ-R provides a measurement tool that can more precisely and accurately assess hyperacusis in individuals with tinnitus. The improvements will be an important resource for clinicians and researchers working with tinnitus patients.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"499-505"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2025-06-01Epub Date: 2025-04-22DOI: 10.1080/00016489.2025.2486611
Srivatsa Surya Vasudevan, Estephania Candelo, Anyull D Bohorquez Caballero, Katerina J Green, Tiba Yamin Kandrikar, Jeffrey R Janus
{"title":"Current Diagnostics and management of submandibular space schwannoma: a systematic review.","authors":"Srivatsa Surya Vasudevan, Estephania Candelo, Anyull D Bohorquez Caballero, Katerina J Green, Tiba Yamin Kandrikar, Jeffrey R Janus","doi":"10.1080/00016489.2025.2486611","DOIUrl":"10.1080/00016489.2025.2486611","url":null,"abstract":"<p><strong>Background: </strong>Submandibular space schwannomas (SSS) are rare tumors originating from the neural sheath in the submandibular region with varied prognoses.</p><p><strong>Objective: </strong>The primary objective was to evaluate the current diagnostic and management outcomes of SSS.</p><p><strong>Material and methods: </strong>PubMed, Embase, Science Direct, and Web of Science were reviewed for articles from inception through January 2025. Fisher's test was used to calculate the difference in outcomes between extraglandular (EG) and intraglandular (IG) subtypes.</p><p><strong>Results: </strong>A total of 44 studies with 47 patients were included with a mean age (SD) of 42.8 (19.3) years. Hypoglossal nerve (43.3%) and lingual nerve (36.6%) were the primary nerve of origin for SSS, with significantly higher rates of hypoglossal nerve origin in EG-SSS than IG-SSS (<i>p</i> = .008). Sensitivity analysis of preoperative biopsy showed higher sensitivity rates with core biopsy compared to fine-needle aspiration cytology (FNAC) (85.7% vs. 38.7%) in SSS diagnosis. IG schwannomas are more likely to undergo submandibular gland excision (<i>p</i> = .002) than EG schwannoma.</p><p><strong>Conclusion: </strong>Core biopsy demonstrated superior sensitivity compared to FNAC, establishing it as the preferred diagnostic tool. The hypoglossal nerve was the most identified nerve of origin.</p><p><strong>Significance: </strong>This review offers a comprehensive insight into the preoperative and perioperative management of SSS subtypes for surgeon decisions.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"545-553"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Oto-LaryngologicaPub Date : 2025-06-01Epub Date: 2025-04-08DOI: 10.1080/00016489.2025.2476188
Emma M Teunissen, Tjerk W Aukema, Coosje J I Caspers, Kim H E Bakkum, Ivo J Kruyt, Froukje L J Cals, Emmanuel A M Mylanus, Myrthe K S Hol
{"title":"Single-stage bone-anchored hearing implant surgery in children: a prospective comparative study.","authors":"Emma M Teunissen, Tjerk W Aukema, Coosje J I Caspers, Kim H E Bakkum, Ivo J Kruyt, Froukje L J Cals, Emmanuel A M Mylanus, Myrthe K S Hol","doi":"10.1080/00016489.2025.2476188","DOIUrl":"10.1080/00016489.2025.2476188","url":null,"abstract":"","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"491-498"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara H Pinborg, Amanda-Louise F Carlander, Joachim Hansen, Christian Grønhøj, Kathrine K Jakobsen, Christian von Buchwald
{"title":"Prognostic impact of p16 and HPV discordance in cancer of unknown primary: a systematic review and meta-analysis.","authors":"Clara H Pinborg, Amanda-Louise F Carlander, Joachim Hansen, Christian Grønhøj, Kathrine K Jakobsen, Christian von Buchwald","doi":"10.1080/00016489.2025.2509655","DOIUrl":"https://doi.org/10.1080/00016489.2025.2509655","url":null,"abstract":"<p><strong>Background: </strong>Discordance between human papillomavirus (HPV) and its surrogate marker, p16INK4a (p16), raises concerns about the reliability of p16 as a sole prognostic marker.</p><p><strong>Objectives: </strong>To investigate the impact of HPV, p16, and discordant HPV/p16 status on survival in squamous cell carcinoma of unknown primary in the head and neck (SCCUPHN).</p><p><strong>Materials and methods: </strong>PubMed and EMBASE were searched for relevant studies that used a strict definition of SCCUPHN and reported survival outcomes stratified by HPV/p16 status. A meta-analysis assessed the prevalence and overall survival (OS).</p><p><strong>Results: </strong>Twelve studies (<i>n</i> = 864) were included. The pooled prevalence rates were: 23% HPV+/p16+ SCCUPHN (95% CI: 14-33%); 50% HPV-/p16- (95% CI: 32-67%); 13% HPV-/p16+ (95% CI: 6-19%); and 6% HPV+/p16- (95% CI: 1-10%). OS hazard ratios were: 0.37 (95% CI: 0.17-0.78) for p16+ vs. p16-, 0.35 (95% CI: 0.19-0.64) for HPV+ vs. HPV-, and 0.24 (95% CI: 0.12-0.50) for HPV+/p16+ vs. HPV-/p16-. Only one study (<i>n</i> = 103) compared survival in the four HPV/p16 subgroups individually.</p><p><strong>Conclusions: </strong>HPV and p16 are individual positive prognostic markers in SCCUPHN. Although significant discordance exists, the current literature does not provide sufficient evidence to support risk stratifying SCCUPHN patients into four distinct HPV/p16 subgroups.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between mastoid pneumatization and antrochoanal polyps in pediatric patients.","authors":"Gamze Ozturk Yilmaz, Gokhan Yilmaz, Nevfel Kahvecioglu, Erdem Atalay Cetinkaya, Omer Tarik Selcuk, Ozer Erdem Gur, Hulya Eyigor","doi":"10.1080/00016489.2025.2510503","DOIUrl":"https://doi.org/10.1080/00016489.2025.2510503","url":null,"abstract":"<p><strong>Background: </strong>Mastoid pneumatization reflects middle ear aeration and may be disrupted in chronic inflammatory conditions such as Antrochoanal polyps (AP), potentially predisposing children to otologic complications.</p><p><strong>Objective: </strong>We aimed to investigate the developmental relationship between AP volume and total mastoid air cell volume (TMCV).</p><p><strong>Methods: </strong>The correlation between the volume of nasal polyps and TMCV was assessed in 21 pediatric patients with AP. TMCV on the side not affected by AP served as the control within each patient. Polyp volume and TMCV were quantified using computed tomography (CT)-based 3D reconstruction.</p><p><strong>Results: </strong>The mean TMCV on the side with AP was 7.68 ± 6.13 cm³, while the mean TMCV on the contralateral side was 8.44 ± 6.67 cm³. This difference was statistically significant (<i>p</i> = 0.042). However, no statistically significant correlation was observed between polyp volume and TMCV on the affected side (<i>p</i> = 0.758).</p><p><strong>Conclusion: </strong>Our results suggest that AP may have a negative effect on mastoid pneumatization. Further research with larger cohorts is warranted.</p><p><strong>Significance: </strong>These findings highlight the need for comprehensive radiologic evaluation in children with AP to monitor potential mastoid involvement.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-4"},"PeriodicalIF":1.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Na Zhang, Xiaobo Ma, Danni Wang, Yi Li, Yan Zheng, Yongxin Li, Shouqin Zhao
{"title":"Impact of age on hearing outcomes following stapes surgery for otosclerosis: a retrospective study.","authors":"Na Zhang, Xiaobo Ma, Danni Wang, Yi Li, Yan Zheng, Yongxin Li, Shouqin Zhao","doi":"10.1080/00016489.2025.2504040","DOIUrl":"https://doi.org/10.1080/00016489.2025.2504040","url":null,"abstract":"<p><strong>Background: </strong>Otosclerosis causes progressive hearing loss, with stapes surgery being the most effective treatment. However, the influence of age on postoperative outcomes remains debated.</p><p><strong>Objective: </strong>To evaluate the impact of age on hearing outcomes following stapes surgery.</p><p><strong>Methods: </strong>This retrospective study included patients who underwent primary stapes surgery (2010-2024), excluding those with revision surgeries or confirmed cochlear otosclerosis. Pre- and postoperative pure-tone audiometry assessed air conduction (AC), bone conduction (BC), and air-bone gap (ABG) across age groups.</p><p><strong>Results: </strong>This study included 177 patients (188 ears) aged 18-68 years. Significant improvements in AC thresholds and ABG closure were observed across all age groups (<i>p</i> < 0.05). BC thresholds improved significantly in patients <50 years. Linear regression revealed a modest negative correlation between age and AC improvement (<i>R</i><sup>2</sup> = 0.18, <i>p</i> = 0.006). Despite smaller gains in older patients, both age groups demonstrated substantial improvements AC thresholds and ABG, with minimal changes in BC thresholds. No significant differences were found between younger and older groups in changes in BC, AC, or ABG closure (all <i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Stapes surgery significantly improves hearing outcomes across all ages, especially in AC thresholds and ABG closure. Age should not be a contraindication if audiological criteria are met.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-5"},"PeriodicalIF":1.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of vestibular rehabilitation in patients with residual dizziness after treatment for benign paroxysmal positional vertigo.","authors":"Tomoyuki Shiozaki, Masaharu Sakagami, Tadao Okayasu, Takao Imai, Tadashi Kitahara","doi":"10.1080/00016489.2025.2506671","DOIUrl":"https://doi.org/10.1080/00016489.2025.2506671","url":null,"abstract":"<p><strong>Background: </strong>Benign paroxysmal positional vertigo (BPPV) is a prevalent cause of vertigo. Although canalith repositioning procedures are effective, some patients continue to experience residual dizziness (RD) and balance disturbances that adversely affect daily activities.</p><p><strong>Aims/objectives: </strong>This study aimed to assess the impact of vestibular rehabilitation on patients with RD following BPPV treatment.</p><p><strong>Material and methods: </strong>Thirty participants were allocated into two groups: a rehabilitation group (Group 1) that received weekly physiotherapy and performed home exercises for six months and an aerobic exercise instruction group (Group 2) that attended bi-monthly sessions. Outcome measures included the modified Dizziness Handicap Inventory (mDHI), posturography, Functional Gait Assessment (FGA), and Self-rating Depression Scale (SDS).</p><p><strong>Results: </strong>Both groups demonstrated significant improvements in mDHI and FGA scores pre- and post-intervention. However, only Group 1 exhibited a significant improvement in centre of pressure movement with eyes closed (COP EC) after the intervention. When comparing the two groups, post-intervention mDHI and COP EC scores showed significantly greater improvement in Group 1.</p><p><strong>Conclusions and significance: </strong>These findings suggest that vestibular rehabilitation may enhance dizziness resolution and postural control in patients with RD.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louise Devantier, Henriette Edemann Callesen, Dan Dupont Hougaard, Bjarki Ditlev Djurhuus, Frank Liviu-Adelin Guldfred, Jesper Hvass Schmidt
{"title":"A systematic review and meta-analysis of intratympanic gentamicin for patients with Ménières disease.","authors":"Louise Devantier, Henriette Edemann Callesen, Dan Dupont Hougaard, Bjarki Ditlev Djurhuus, Frank Liviu-Adelin Guldfred, Jesper Hvass Schmidt","doi":"10.1080/00016489.2025.2504033","DOIUrl":"https://doi.org/10.1080/00016489.2025.2504033","url":null,"abstract":"<p><strong>Background: </strong>Ménière's disease is a chronic inner ear disorder characterized by recurrent vertigo, tinnitus, aural fullness, and fluctuating sensorineural hearing loss. For patients with debilitating symptoms unresponsive to conservative treatment, intratympanic gentamicin is a therapeutic option. However, its efficacy and safety remain uncertain.</p><p><strong>Aims/objectives: </strong>This systematic review aims to evaluate the effectiveness and safety of intratympanic gentamicin in Ménière's disease, focusing exclusively on randomized controlled trials (RCTs).</p><p><strong>Material and methods: </strong>A comprehensive literature search was conducted to identify RCTs comparing intratympanic gentamicin with placebo or no treatment. Primary outcomes included vertigo frequency and severity, quality of life, and incidence of serious adverse events. Data were analyzed using the GRADE approach to assess risk of bias and certainty of evidence.</p><p><strong>Results: </strong>Three RCTs were included, demonstrating a significant reduction in vertigo frequency and severity in patients treated with intratympanic gentamicin compared to placebo. However, the evidence quality was rated very low due to small sample sizes and methodological limitations.</p><p><strong>Conclusions and significance: </strong>Findings suggest that intratympanic gentamicin may reduce vertigo in Ménière's disease. However, due to the limited certainty of the evidence, further research with larger sample sizes and standardized outcome measures is necessary to clarify its benefits and risks.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oliver Skjoedt Joergensen, Vitus Bugge Roennstad, Bo Baslund, Magne Bech, Ditte Gertz Mogensen, Kasper Aanaes
{"title":"Improving olfactory function and sinonasal manifestations in patients with granulomatosis with polyangiitis (GPA) - a prospective intervention study.","authors":"Oliver Skjoedt Joergensen, Vitus Bugge Roennstad, Bo Baslund, Magne Bech, Ditte Gertz Mogensen, Kasper Aanaes","doi":"10.1080/00016489.2025.2502564","DOIUrl":"https://doi.org/10.1080/00016489.2025.2502564","url":null,"abstract":"<p><strong>Background: </strong>No guidelines exist and very few papers are written suggesting how to treat chronic rhinosinusitis (CRS) in granulomatosis with polyangiitis (GPA) patients.</p><p><strong>Aims and objectives: </strong>We conducted this prospective non-randomized intervention study to define the disease burden in GPA and to optimize the CRS treatment attempting to alleviate the symptoms with a special focus on whether the olfactory function could be improved.</p><p><strong>Materials and methods: </strong>We included 30 participants with GPA, who underwent olfactory training therapy combined with nasal corticosteroids twice a day for six months. At the first and second out-patient visits, the following data were collected: patients' CRS symptom were scored using a Visual Analog Scale (VAS), Sinonasal Outcome Test 22 (SNOT-22), Kennedy-Lund endoscopic score, and an olfactory threshold, discrimination, and identification (TDI) test.</p><p><strong>Results: </strong>The patients with few crusts and high compliance improved their olfactory function significantly. The total cohort improved their SNOT-22 score and the facial pain subdomain significantly. No significant improvements were made regarding the VAS score.</p><p><strong>Conclusions and significance: </strong>This study identified that GPA patients' CRS symptoms can be alleviated, using nasal corticosteroids and smell training therapy. Nevertheless, patients with GPA still have a high CRS-disease burden, mostly suffering from nasal crusting.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenna Felder, Karin A Koinig, Ilona Anderson, Angelika Illg, Mareike Billinger-Finke
{"title":"Validation and psychometric properties of the quality of life in people with hearing loss questionnaire (HL-QoL) in English.","authors":"Jenna Felder, Karin A Koinig, Ilona Anderson, Angelika Illg, Mareike Billinger-Finke","doi":"10.1080/00016489.2025.2504636","DOIUrl":"https://doi.org/10.1080/00016489.2025.2504636","url":null,"abstract":"<p><strong>Background: </strong>The Quality of Life in People with Hearing Loss Questionnaire (HL-QoL) measures quality of life (QoL) in individuals with hearing loss. The German version of the HL-QoL was validated in cochlear implant (CI) users.</p><p><strong>Objectives: </strong>Validation of the English version of the HL-QoL.</p><p><strong>Material and methods: </strong>The HL-QoL was forward-backward translated. 97 participants were included in the HL-QoL validation. Item and scale analyses assessed the quality of individual items and of the questionnaire in its entirety.</p><p><strong>Results: </strong>Questionnaire validation results confirmed item difficulty and item discrimination, good test reliability and construct and discriminant validity. The mean total HL-QoL score was 103 points, which indicates a 'high' quality of life. 94% of participants reported at least a 'moderate' quality of life benefit. Participants tended to have a higher QoL when their hearing loss was fully addressed, i.e. biltaral CI users with bilateral hearing loss. QoL did not correlate with age, duration of CI use, sex, or gender.</p><p><strong>Conclusion: </strong>The English version of the HL-QoL is a valid tool to assess how hearing loss and its treatment can impact an individual's quality of life. The mean total HL-QoL score suggests an overall high QoL benefit in this sample of CI users.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}