Acta Oto-Laryngologica最新文献_第3页

Plasminogen - safe for treatment of chronic tympanic membrane perforation: a phase 1 randomized, placebo-controlled study. Plasminogen - 用于治疗慢性鼓膜穿孔的安全性：1 期随机、安慰剂对照研究。

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-12 DOI: 10.1080/00016489.2024.2396488

Elnaz Sepehri,Bo Tideholm,Sten Hellström,Cecilia Engmér Berglin

{"title":"Plasminogen - safe for treatment of chronic tympanic membrane perforation: a phase 1 randomized, placebo-controlled study.","authors":"Elnaz Sepehri,Bo Tideholm,Sten Hellström,Cecilia Engmér Berglin","doi":"10.1080/00016489.2024.2396488","DOIUrl":"https://doi.org/10.1080/00016489.2024.2396488","url":null,"abstract":"BACKGROUNDThere is a need for a simpler and accessible intervention to heal tympanic membrane perforations than myringoplasty that is todaýs golden standard. Experimental studies have identified plasminogen as a promising agent for medical treatment of chronic tympanic membrane perforation.AIMS/OBJECTIVESThis was a phase 1, prospective, randomized, placebo-controlled study with the main objective to evaluate the safety of injecting plasminogen in the vicinity of the tympanic membrane in subjects with chronic tympanic membrane perforation.MATERIAL AND METHODSAdults diagnosed with a dry chronic tympanic membrane perforation were recruited for an injection schedule with Human plasminogen 10. Adverse events, audiometry, VAS fluctuations and size of perforation, were monitored throughout the length of the study.RESULTSIt was possible to perform the injections according to schedule in all subjects. None of the subjects experienced any severe adverse events. Most common adverse event was ear pain. No signs of ototoxicity were reported.CONCLUSIONS AND SIGNIFICANCEThis pilot study suggests that plasminogen injections close to the tympanic membrane as treatment for chronic tympanic membrane injections are safe and feasible, encouraging further dose-escalating studies.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"8 1","pages":"1-7"},"PeriodicalIF":1.4,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142227166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of adverse reactions on adherence to sublingual immunotherapy for Japanese cedar pollinosis and house dust mite allergy in Japan. 在日本，不良反应对坚持使用舌下免疫疗法治疗杉树花粉症和屋尘螨过敏症的影响。

IF 1.4 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-12 DOI: 10.1080/00016489.2024.2397054

Satoru Masuno

{"title":"The impact of adverse reactions on adherence to sublingual immunotherapy for Japanese cedar pollinosis and house dust mite allergy in Japan.","authors":"Satoru Masuno","doi":"10.1080/00016489.2024.2397054","DOIUrl":"https://doi.org/10.1080/00016489.2024.2397054","url":null,"abstract":"BACKGROUNDAllergen immunotherapy is the only treatment that can achieve remission for allergic diseases.AIMS/OBJECTIVESTo investigate the three-year adherence to sublingual immunotherapy for Japanese cedar pollinosis and house dust mite allergy at a clinic in Japan and identify factors that influence adherence and severe adverse reactions.MATERIAL AND METHODSIn total, 174 patients aged 12 years or older who started sublingual immunotherapy for Japanese cedar pollinosis (n = 72), house dust mite allergy (n = 55), or both (n = 47) between May 2017 and June 2018. Patient age, sex, type of pharmacotherapy used, adverse reactions, blood test results, and duration of continuous treatment were investigated.RESULTSThe three-year treatment continuation rate was 40.8%. Adverse reaction rates were 12.6% for cedar pollinosis and 40.2% for house dust mite allergy. Patients with dose reductions due to severe reactions had lower first-year continuation rates. In the MITICURE® group, patients with severe reactions had significantly higher serum total IgE levels. Severe reactions were more common in MITICURE® patients with seven or more positive antigen types.CONCLUSIONS AND SIGNIFICANCESevere adverse reactions reduced early adherence.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":"59 1","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of covered stent implantation combined with radical tumor resection in advanced head and neck squamous cell carcinoma involving the carotid artery: a comparative study with historical literature. 覆盖支架植入联合肿瘤根治性切除术在累及颈动脉的晚期头颈部鳞状细胞癌中的应用：与历史文献的比较研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-09-20 DOI: 10.1080/00016489.2024.2400299

Haidong Zhang, Kai Sun, Shanchun Gong, Lijuan Zhou, Siping Liang, Chao Wang, Kai Liu, Xianjun Lyn, Zhenkun Yu

{"title":"Application of covered stent implantation combined with radical tumor resection in advanced head and neck squamous cell carcinoma involving the carotid artery: a comparative study with historical literature.","authors":"Haidong Zhang, Kai Sun, Shanchun Gong, Lijuan Zhou, Siping Liang, Chao Wang, Kai Liu, Xianjun Lyn, Zhenkun Yu","doi":"10.1080/00016489.2024.2400299","DOIUrl":"10.1080/00016489.2024.2400299","url":null,"abstract":"Background: Studies have shown that carotid artery reconstruction results in the best overall survival (OS) in Advanced Head and Neck Squamous Cell Carcinoma involving the Carotid Artery (AHNSCC-CA).Aims: The purpose of this study was to evaluate the efficacy of covered stent implantation combined with radical tumor resection and to compare and analyze the historical literature on conventional carotid artery resection and reconstruction.Materials and methods: A total of 68 patients with AHNSCC-CA were included in this study. This study compared the survival, local recurrence, surgical complications, and neurologic complications between the two groups.Results: The OS rate at 12 months in the experimental group was 58.5% (median survival time: 15 months, 95% CI: 7.61-22.40). The OS rate at 12 months in the control group was 34.3% (median survival time: 8 months, 95% CI: 3.94-12.06, p = .371). In addition, the differences in the rates of local recurrence, surgical complications and neurological complications between the two groups were statistically insignificant (p = .677, p = .197 and p = .617).Conclusions and significance: Compared with conventional carotid artery resection and reconstruction, covered stent implantation combined with radical tumor resection yields similar survival outcomes, but with significantly lower surgical risk and difficulty, and faster postoperative recovery.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"524-530"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Baseline eosinophil proportion is a useful predictor of immune-related adverse events following immune checkpoint inhibitor treatment for recurrent metastatic head and neck cancer. 基线嗜酸性粒细胞比例是免疫检查点抑制剂治疗复发性转移性头颈癌后免疫相关不良事件的有效预测指标。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-09-20 DOI: 10.1080/00016489.2024.2390084

Takayoshi Hattori, Tsutomu Ueda, Yuki Sato, Nobuyuki Chikuie, Takayuki Taruya, Takao Hamamoto, Minoru Hattori, Takashi Ishino, Sachio Takeno

{"title":"Baseline eosinophil proportion is a useful predictor of immune-related adverse events following immune checkpoint inhibitor treatment for recurrent metastatic head and neck cancer.","authors":"Takayoshi Hattori, Tsutomu Ueda, Yuki Sato, Nobuyuki Chikuie, Takayuki Taruya, Takao Hamamoto, Minoru Hattori, Takashi Ishino, Sachio Takeno","doi":"10.1080/00016489.2024.2390084","DOIUrl":"10.1080/00016489.2024.2390084","url":null,"abstract":"Background: Immune checkpoint inhibitors (ICIs) occasionally cause immune-related adverse events (irAEs) in various organs. However, predictors of irAEs remain unidentified.Objectives: We evaluated the predictors of irAEs and compared the outcomes of ICIs with and without irAEs in patients with recurrent/metastatic head and neck cancers (R/M HNCs).Materials and methods: We retrospectively analyzed 157 patients with R/M HNCs who were administered an anti-PD-1 antibody between September 2014 and December 2022. We examined whether various pretreatment factors were associated with irAEs. The overall survival (OS) and progression-free survival (PFS) in patients with and without irAEs were analyzed.Results: Overall, 44 patients (28.0%) developed irAEs. The survival curve estimated for patients with and without irAEs showed a significant difference in PFS (p = 0.018), but not in OS (p = 0.208). Multivariate analysis revealed significant differences in relative eosinophil counts (p < 0.001), TP (p = 0.014), and NLR (p = 0.002), which may be independent predictors of irAEs.Conclusion: IrAEs may be associated with higher efficacy of ICIs and longer PFS. The relative eosinophil count may be predictors of irAEs and useful in routine medical practice. Using these biomarkers to predict irAEs will help predict ICI effects and manage irAEs.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"515-523"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 更正。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-10-10 DOI: 10.1080/00016489.2024.2411777

引用次数: 0

The characteristics of three-dimensional real inversion recovery MRI sequence in delayed Meniere's disease. 延迟性美尼尔氏病的三维真实反转恢复磁共振成像序列特征。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-09-20 DOI: 10.1080/00016489.2024.2402542

Xu Liu, Linying Guo, Suming Shi, Wuqing Wang

{"title":"The characteristics of three-dimensional real inversion recovery MRI sequence in delayed Meniere's disease.","authors":"Xu Liu, Linying Guo, Suming Shi, Wuqing Wang","doi":"10.1080/00016489.2024.2402542","DOIUrl":"10.1080/00016489.2024.2402542","url":null,"abstract":"Background: Delayed Meniere's disease (DMD) is characterized by episodic vertigo occurring after a significant delay following longstanding sensorineural hearing loss. However, its pathogenesis and characteristics remain unclear.Objectives: To explore the characteristics of endolymphatic hydrops (EH) in DMD and investigate its pathology using MRI.Materials and methods: 17 patients diagnosed with DMD were included in this study. A 3D-real-IR MRI sequence was utilized to visualize and grade EH. The signal intensity of the basal cochlear turn was compared to that of the cerebellar white matter to calculate the CC ratio. A paired t-test was employed to assess the differences in the CC ratio between the affected and unaffected sides in patients with unilateral DMD.Results: EH was present in 100% of cases on the affected side. Unilateral EH was seen in 82.4%, and bilateral EH in 23.5%. Vestibular EH without cochlear involvement occurred in 29.4%, and cochlear EH without vestibular involvement in 5.9%. The CC ratio was significantly higher on the affected side (p < 0.01).Conclusions and significance: A significant grade of vestibular EH was observed in DMD, with bilateral EH being relatively common. The increased contrast on the affected side may reflect the underlying pathology in DMD patients.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"491-494"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Based on the clinical features of cytologically intrinsic chronic rhinosinusitis with nasal polyps. 根据细胞学内在性慢性鼻窦炎伴鼻息肉的临床特征。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-09-21 DOI: 10.1080/00016489.2024.2396487

Ruru Tian, Jianhua Jiang, Xiangyan Wu, Jie Ling Zhao, Xin Ru Zhou, Jinv Ding

{"title":"Based on the clinical features of cytologically intrinsic chronic rhinosinusitis with nasal polyps.","authors":"Ruru Tian, Jianhua Jiang, Xiangyan Wu, Jie Ling Zhao, Xin Ru Zhou, Jinv Ding","doi":"10.1080/00016489.2024.2396487","DOIUrl":"10.1080/00016489.2024.2396487","url":null,"abstract":"Background: The clinical phenotypes of CRS, such as the presence or absence of polyps, cannot well reflect the pathophysiological mechanisms and characteristics of patients. Only by distinguishing the different internal types of CRS can we individualize patients more accurately.Objective: To investigate the clinical characteristics of chronic rhinosinusitis with different cell types (CRSwNP), and to provide a reference for the diagnosis and treatment of CRSwNP.Materials and methods: The cytological endotypes of CRSwNP were divided into five groups by cluster analysis.Results: There was a significant difference in the proportion of CRSwNP with different endotypes. There were significant differences in peripheral blood eosinophils, cerebrovascular disease, and unilateral and bilateral nasal polyps among CRSWNP patients with different cytological types.Conclusions: Mixed CRSwNP and eosinophilic CRSwNP are the most common, while neutrophilic CRSWNP is the least common. Eosinophilic CRSwNP is more common in bilateral nasal polyps, with a high recurrence rate and a high probability of olfactory dysfunction. Neutrophilic CRSwNP is more common in elderly patients with cardiovascular and cerebrovascular diseases. Compared with total serum IgE, the percentage of eosinophils in peripheral blood is more helpful for the diagnosis of eosinophilic CRSwNP.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"509-514"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shifting paradigms in endoscopic sinus surgery: a comprehensive analysis from Japan's national database. 内窥镜鼻窦手术模式的转变：来自日本国家数据库的综合分析。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-08-12 DOI: 10.1080/00016489.2024.2389179

Seiichiro Makihara, Kensuke Uraguchi, Shohei Fujimoto, Aiko Shimizu, Shin Kariya, Mitsuhiro Okano, Takashi Yorifuji, Mizuo Ando

{"title":"Shifting paradigms in endoscopic sinus surgery: a comprehensive analysis from Japan's national database.","authors":"Seiichiro Makihara, Kensuke Uraguchi, Shohei Fujimoto, Aiko Shimizu, Shin Kariya, Mitsuhiro Okano, Takashi Yorifuji, Mizuo Ando","doi":"10.1080/00016489.2024.2389179","DOIUrl":"10.1080/00016489.2024.2389179","url":null,"abstract":"Background: In 2013, Japan established a standardized classification system for categorizing endoscopic sinus surgery (ESS) into types I-V, yet no evaluation has been conducted thereof.Objective: We assessed the ESS trends and status in Japan, focusing on outpatient and inpatient surgeries.Material and methods: This descriptive retrospective cohort study used Japan's National Database of Health Insurance Claims and Specific Health Checkups between 2014 and 2021. The distribution of ESS types I-V and outpatient and inpatient surgeries was analysed, along with age groups and regional differences, focusing on ESS type III.Results: Overall, 427,813 ESS procedures were performed, with types III and IV being most common. Outpatient ESS type III increased substantially compared to inpatient surgeries. Younger individuals favoured outpatient ESS type III over inpatient surgeries, with substantial regional variations across prefectures.Conclusions and significance: The adoption of a standardized ESS classification in Japan has facilitated a detailed understanding of surgical trends. The shift toward outpatient surgeries, especially for type III ESS, aligns with global trends toward minimally invasive procedures and reflects changing patient preferences and healthcare delivery practices. Consequently, continuous monitoring and research are crucial for adapting surgical practices to the evolving healthcare needs and patient expectations.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"503-508"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141915833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Otolith function in Usher type II syndrome. 乌谢尔 II 型综合征的耳石功能。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-08-16 DOI: 10.1080/00016489.2024.2390661

Ana Margarida Amorim, Diliana Rebelo, Ana Beatriz Ramada, Ana Cristina Lopes, João Lemos, João Carlos Ribeiro

{"title":"Otolith function in Usher type II syndrome.","authors":"Ana Margarida Amorim, Diliana Rebelo, Ana Beatriz Ramada, Ana Cristina Lopes, João Lemos, João Carlos Ribeiro","doi":"10.1080/00016489.2024.2390661","DOIUrl":"10.1080/00016489.2024.2390661","url":null,"abstract":"Background: Usher's syndrome type II (USH2) is a rare genetic disorder encompassing hearing loss, vision impairment, and apparent intact vestibular function. Recent research suggests a potential involvement of the otolith vestibular receptors in USH2.Aims/objectives: Evaluate otolith dynamic function in USH2.Material and methods: Twenty-two USH2 (median age 53.9 ± 2.99) and age-matched controls underwent a complete battery vestibular testing including air conducted cervical and ocular vestibular evoked myogenic potentials (c-VEMPs and o-VEMPs). Vestibular function tests were correlated with Activities Balance Scale (ABC) and Dizziness Handicap Inventory (DHI) scores.Results: Fourteen USH2 reported previous vertigo (vs none control). Among 88 ears, c-VEMPs were absent in 15 USH2 cases and 4 controls (p = 0.034), while o-VEMPs were absent in 22 USH2 cases and 12 controls (p = 0.129). There were significant differences between USH2 vs controls in right ear o-VEMP N1 latencies (median 11.60/10.40, p < 0.010), N1-P1 amplitudes (median 5.15/10.10, p < 0.003) and in o-VEMP N1-P1 asymmetry ratio (median 24.78/40.50, p < 0.014). USH2 showed a strong correlation between o-VEMP amplitude and DHI score (p = 0.003, ρ = 0.769). No association was found between vertigo and VEMPs subgroups.Conclusions and significance: Our findings suggest the presence of otolith dysfunction in USH2, which is independent from subjectively reported dizziness. Incorporating vestibular testing into USH2 evaluation and monitoring could enhance characterization of this multisensory disease.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"485-490"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141992240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between thyroid disease and hearing loss: a meta-analysis. 甲状腺疾病与听力损失之间的关系：一项荟萃分析。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2024-09-01 Epub Date: 2024-10-02 DOI: 10.1080/00016489.2024.2404614

Li Gu, Wei Guo, Xinli Wang, Chuan Yue

{"title":"The association between thyroid disease and hearing loss: a meta-analysis.","authors":"Li Gu, Wei Guo, Xinli Wang, Chuan Yue","doi":"10.1080/00016489.2024.2404614","DOIUrl":"10.1080/00016489.2024.2404614","url":null,"abstract":"Background: It has been shown that there is a link between thyroid-related diseases and hearing loss.Objectives: The purpose of this study is to investigate the relationship between thyroid-related diseases and hearing loss by conducting a meta-analysis.Material and methods: A thorough search was carried out in the following electronic databases: PubMed, Cochrane Library, Embase, Web of Science, Google Scholar, Semantic Scholar, and ResearchRabbit. The chi-square test and the I2 index examined the research's heterogeneity. A funnel plot and the Eger test were used to examine publication-biased effects.Results: A total of 48,507 individuals (6482 hypothyroid patients, 4162 hearing loss patients, and 37863 controls) were included in this meta-analysis of 18 research. Individuals with hypothyroidism had a 1.69-fold increased risk of hearing loss compared to those without the condition (OR: 1.69; 95% CI: 1.11-2.57, p < 0.001). among hypothyroidism, the prevalence of hearing loss was 24% (EC: 0.24; 95% CI: 0.11-0.39, p = 0.00), while among hearing-impaired individuals, the prevalence of hypothyroidism was 7% (EC: 0.21; 95% CI: 0.07-0.40).Conclusion: This study demonstrated how thyroid dysfunction can raise the chance of hearing loss. To completely comprehend the underlying mechanisms and create efficient treatments for this illness, more study is required.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"495-502"},"PeriodicalIF":1.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142363839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0