Acta Oto-Laryngologica最新文献

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Improving olfactory function and sinonasal manifestations in patients with granulomatosis with polyangiitis (GPA) - a prospective intervention study. 改善肉芽肿合并多血管炎(GPA)患者的嗅觉功能和鼻窦表现——一项前瞻性干预研究。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-20 DOI: 10.1080/00016489.2025.2502564
Oliver Skjoedt Joergensen, Vitus Bugge Roennstad, Bo Baslund, Magne Bech, Ditte Gertz Mogensen, Kasper Aanaes
{"title":"Improving olfactory function and sinonasal manifestations in patients with granulomatosis with polyangiitis (GPA) - a prospective intervention study.","authors":"Oliver Skjoedt Joergensen, Vitus Bugge Roennstad, Bo Baslund, Magne Bech, Ditte Gertz Mogensen, Kasper Aanaes","doi":"10.1080/00016489.2025.2502564","DOIUrl":"10.1080/00016489.2025.2502564","url":null,"abstract":"<p><strong>Background: </strong>No guidelines exist and very few papers are written suggesting how to treat chronic rhinosinusitis (CRS) in granulomatosis with polyangiitis (GPA) patients.</p><p><strong>Aims and objectives: </strong>We conducted this prospective non-randomized intervention study to define the disease burden in GPA and to optimize the CRS treatment attempting to alleviate the symptoms with a special focus on whether the olfactory function could be improved.</p><p><strong>Materials and methods: </strong>We included 30 participants with GPA, who underwent olfactory training therapy combined with nasal corticosteroids twice a day for six months. At the first and second out-patient visits, the following data were collected: patients' CRS symptom were scored using a Visual Analog Scale (VAS), Sinonasal Outcome Test 22 (SNOT-22), Kennedy-Lund endoscopic score, and an olfactory threshold, discrimination, and identification (TDI) test.</p><p><strong>Results: </strong>The patients with few crusts and high compliance improved their olfactory function significantly. The total cohort improved their SNOT-22 score and the facial pain subdomain significantly. No significant improvements were made regarding the VAS score.</p><p><strong>Conclusions and significance: </strong>This study identified that GPA patients' CRS symptoms can be alleviated, using nasal corticosteroids and smell training therapy. Nevertheless, patients with GPA still have a high CRS-disease burden, mostly suffering from nasal crusting.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"640-647"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic hearing thresholds after glycerol ingestion may be modified by endolymphatic hydrops status in Ménière's disease. 摄入甘油后的动态听力阈值可能会因内淋巴积液状态而改变。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-16 DOI: 10.1080/00016489.2025.2489646
Hui Pan, Ping Lei, Qin Liu, Yingzhao Liu, Kaijun Xia, Xingqian Shen, Xiaoye Chen, Ziying Xu, Wenliang Fan, Yangming Leng, Bo Liu
{"title":"Dynamic hearing thresholds after glycerol ingestion may be modified by endolymphatic hydrops status in Ménière's disease.","authors":"Hui Pan, Ping Lei, Qin Liu, Yingzhao Liu, Kaijun Xia, Xingqian Shen, Xiaoye Chen, Ziying Xu, Wenliang Fan, Yangming Leng, Bo Liu","doi":"10.1080/00016489.2025.2489646","DOIUrl":"10.1080/00016489.2025.2489646","url":null,"abstract":"<p><strong>Background: </strong>Endolymphatic hydrops (ELH) can be identified by electrophysiological and radiological examinations.</p><p><strong>Objectives: </strong>We aimed to investigate the relationship between audiometric glycerol test and delayed magnetic resonance imaging (MRI) of the inner ear after intratympanic gadolinium in patients with unilateral Ménière's disease (MD).</p><p><strong>Material and methods: </strong>Forty-two patients with unilateral definite MD underwent audiometric glycerol test and delayed MRI following intratympanic gadolinium application.</p><p><strong>Results: </strong>The degree of cochlear ELH was moderately positively correlated with the mean hearing threshold below 2 kHz. For those ears with positive glycerol results, the best hearing threshold was measured at 3 h and the maximal improvement of hearing threshold was observed within the third hour. The overall positive rates of glycerol test did not differ between ELH (+) and ELH (-) subgroups based on the MRI findings. Significant temporal changes in the positive rate were only observed in the ELH (+) subgroup. The rebound rate did not change significantly over time in either subgroup.</p><p><strong>Conclusions and significance: </strong>In MD patients, glycerol-induced dynamic shift of hearing threshold may be modified by the hydropic status of the inner ear. For those without radiological ELH, glycerol test could be used as additional diagnostic tool to detect hydrops.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"563-570"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental study on the application of irreversible electroporation/nanoknife on tonsil tissues in a rabbit model. 不可逆电穿孔/纳米刀在兔扁桃体组织模型上应用的实验研究。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-23 DOI: 10.1080/00016489.2025.2491652
Xinggang Tao, Jiayan Chen, Zhuo Li, Yihui Sun, Chunyu Shan, Yingfeng Li, Qian Li, Quanqin Hao, Ying Li, Xizhi Yang, Keyong Li
{"title":"Experimental study on the application of irreversible electroporation/nanoknife on tonsil tissues in a rabbit model.","authors":"Xinggang Tao, Jiayan Chen, Zhuo Li, Yihui Sun, Chunyu Shan, Yingfeng Li, Qian Li, Quanqin Hao, Ying Li, Xizhi Yang, Keyong Li","doi":"10.1080/00016489.2025.2491652","DOIUrl":"10.1080/00016489.2025.2491652","url":null,"abstract":"<p><strong>Background: </strong>Irreversible electroporation (IRE)/nanoknife is a nonthermal technique for ablating solid tumors.</p><p><strong>Objectives: </strong>To investigate the application of IRE for ablating tonsil tissues in a rabbit model.</p><p><strong>Material and methods: </strong>Forty five rabbits were divided into three groups IRE, radiofrequency ablation (RFA) and control group. The IRE group received IRE in one or both tonsils, while the RFA group received IRE in one tonsil and RFA in the other. The control group had no operation. Rabbits were euthanized at days 1, 3, 7, 14, and 28 post-IRE ablation or RFA. White blood cell (WBC) counts, C-reactive protein (CRP), and creatine kinase (CK) levels were monitored and tonsil tissues were histologically examined.</p><p><strong>Results: </strong>IRE ablation induced cell apoptosis in tonsil tissues, which was most pronounced at 72 h post-treatment. At 14- and 28-days post-IRE ablation, lymphoid follicles regenerated in the tonsil tissues. The RFA group showed more severe injury and less tissue regeneration. Transient increases in WBC, CRP, and CK levels indicated inflammation and cardiac injury induced by IRE.</p><p><strong>Conclusions and significance: </strong>IRE is a potential modality for ablating tonsil tissues, which avoids thermal injury and preserving blood vessels. More robust studies with other animal models are required for definitive evidence.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"654-660"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traditional and adaptive speech audiometry in single-sided deaf (SSD) subjects rehabilitated by bone conductive implants (BCI), quality of life and long-term utilization. 单侧耳聋经骨传导植入(BCI)康复者的传统和自适应语音测听、生活质量和长期使用。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-17 DOI: 10.1080/00016489.2025.2504032
Edoardo Covelli, Chiara Filippi, Francesco Lazzerini, Elisabetta Tromboni, Silvia Tarentini, Sofia Pizzolante, Francesca Forli, Stefano Berrettini, Luca Bruschini
{"title":"Traditional and adaptive speech audiometry in single-sided deaf (SSD) subjects rehabilitated by bone conductive implants (BCI), quality of life and long-term utilization.","authors":"Edoardo Covelli, Chiara Filippi, Francesco Lazzerini, Elisabetta Tromboni, Silvia Tarentini, Sofia Pizzolante, Francesca Forli, Stefano Berrettini, Luca Bruschini","doi":"10.1080/00016489.2025.2504032","DOIUrl":"10.1080/00016489.2025.2504032","url":null,"abstract":"<p><strong>Background: </strong>Single-sided deafness (SSD) encompasses the presence of a profoundly deaf ear with a normal, contralateral one. Patients with SSD may have difficulty with speech intelligibility in noise and localizing sounds.</p><p><strong>Aims/objectives: </strong>This retrospective study aims to evaluate the long-term effectiveness of bone conduction implant (BCI) in a group of patients with SSD.</p><p><strong>Material and methods: </strong>Audiologic benefit was assessed through conventional speech audiometry and adaptive Matrix test. Impact on quality of life was evaluated with the Glasgow Benefit Inventory (GBI) questionnaire. BCI usage data were also obtained from each subject.</p><p><strong>Results: </strong>Thirty-two patients were included. No statistically significant improvements were found at standard audiometric tests using BCI, but at Matrix test the mean SRT is reached at S/N -1.16 dB without BCI and -2.07 with BCI with a statistically significant difference (<i>p</i> = 0.026). The mean GBI score was 25.12, ranging from -8.3 to 47.2. Ten subjects (31%) discontinued the BCI use overtime.</p><p><strong>Conclusions and significance: </strong>Benefit assessment of BCI in SSD recipients can be difficult. Adaptive audiometric test could be useful. Quality of life measures seem to suggest potential 'beyond-auditory' benefits. SSD recipients can be inconsistent users of BCI.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"633-639"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Auditory and cognitive abilities in patients with chronic kidney disease: a comparative study across stages. 慢性肾脏疾病患者的听觉和认知能力:一项跨阶段的比较研究
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-22 DOI: 10.1080/00016489.2025.2489665
Tuana Saglanmak, Aysenur Kucuk Ceyhan
{"title":"Auditory and cognitive abilities in patients with chronic kidney disease: a comparative study across stages.","authors":"Tuana Saglanmak, Aysenur Kucuk Ceyhan","doi":"10.1080/00016489.2025.2489665","DOIUrl":"10.1080/00016489.2025.2489665","url":null,"abstract":"<p><strong>Background: </strong>The impact of chronic kidney disease (CKD) on peripheral hearing is well documented, but little is known about the impact on auditory processing.</p><p><strong>Aim: </strong>This study aimed to evaluate auditory processing and cognitive abilities in CKD and to assess changes according to the disease phases.</p><p><strong>Materials and methods: </strong>Eighty-nine CKD patients, aged 25-65 (48 study and 41 control) with stages 2-4, participated. Random Gap Detection Test (RGDT), Frequency Pattern Test (FPT), Duration Pattern Test (DPT), the Digit Span Backward Task (DSBT) and the speech discrimination (SD) in noise and in quiet test were employed.</p><p><strong>Results: </strong>The comparison between the two groups indicated significant decreases in test scores for the RGDT, FPT, DPT, DSBT, and SD (in noise) within in the group with CKD (<i>p</i> < .001). The SD (in quiet) test exhibits no difference. There were no significant variations in any evaluated parameter between CKD stages.</p><p><strong>Conclusions and significance: </strong>The results indicate that CKD can impair auditory and cognitive processing, hence affecting SD, especially in challenging auditory environments. Nevertheless, no significant changes were observed across the phases of CKD, suggesting that impairments in these capacities may appear early in the course of the disease.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"613-617"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimation method of dynamic range parameters for cochlear implants based on neural response telemetry threshold. 基于神经响应遥测阈值的人工耳蜗动态范围参数估计方法。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-10 DOI: 10.1080/00016489.2025.2492359
Yao Liu, Yue Wang, Yu Chen, Wei Wang
{"title":"Estimation method of dynamic range parameters for cochlear implants based on neural response telemetry threshold.","authors":"Yao Liu, Yue Wang, Yu Chen, Wei Wang","doi":"10.1080/00016489.2025.2492359","DOIUrl":"10.1080/00016489.2025.2492359","url":null,"abstract":"<p><strong>Background: </strong>There is a lack of correlation studies between subjective behavioral test threshold and neural response telemetry (NRT) thresholds in cochlear implant (CI) patients. At present, there is no predictive model that can predict the parameters of CI adjustment objectively and reliably.</p><p><strong>Objectives: </strong>To explore the correlation between the subjective behavior test method threshold and the NRT thresholds in patients with CI with normal cochlear (NC) morphology and inner ear malformation (IEM). To explore the value of using deep learning technology to predict the parameters of machine adjustment and guide the postoperative machine adjustment.</p><p><strong>Methods: </strong>NRT and subjective behavior tests were conducted on 57 cases of CI patients with NC morphology and 20 cases of IEM using electrodes 1, 6, 11, 16, and 22, respectively. The correlation between the NRT thresholds and T and C values was analyzed. Using deep learning techniques, establish a prediction model based on convolutional neural networks to predict the parameters of machine adjustment of CI.</p><p><strong>Results: </strong>The average NRT thresholds values of the NC group and the IEM group were both greater than the T values, close to and slightly smaller than the C values. The average values of T values, C values, and NRT thresholds in the IEM group were slightly higher than those in the NC group. The NRT thresholds of the both groups is significantly correlated with the C values and T values. The constructed prediction model has high accuracy between the predicted values and the actual values of each electrode. Moreover, the linear regression equation between the predicted and actual values is highly similar.</p><p><strong>Conclusions: </strong>The NRT thresholds is significantly related to the subjective behavior test threshold. The correlation between NRT thresholds and T or C values can be used to assist in CI tuning. Especially for patients with IEM, different machine adjustment strategies should be adopted compared to NC patients. Moreover, the constructed neural network prediction model can also guide the postoperative adjustment of patients with cochlear implants.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"618-626"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does high PD-L1 expression reduce the risk of relapse after definitive surgery in patients with oral cavity cancer? 高PD-L1表达是否能降低口腔癌患者术后复发的风险?
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-04-23 DOI: 10.1080/00016489.2025.2489645
Parvin Babayev, Rashad Ismayilov, Oguz Kuscu, Arif Akyildiz, Olcay Kurtulan, Erim Pamuk, Yesim Gaye Guler Tezel, Ibrahim Halil Gullu
{"title":"Does high PD-L1 expression reduce the risk of relapse after definitive surgery in patients with oral cavity cancer?","authors":"Parvin Babayev, Rashad Ismayilov, Oguz Kuscu, Arif Akyildiz, Olcay Kurtulan, Erim Pamuk, Yesim Gaye Guler Tezel, Ibrahim Halil Gullu","doi":"10.1080/00016489.2025.2489645","DOIUrl":"10.1080/00016489.2025.2489645","url":null,"abstract":"<p><strong>Background: </strong>Uncovering the molecular mechanisms of cancer pathogenesis is crucial for improving survival outcomes.</p><p><strong>Aims: </strong>This study investigates the impact of programmed death ligand 1 (PD-L1) expression on the risk of progression in patients with oral squamous cell carcinoma (OSCC).</p><p><strong>Materials and methods: </strong>The retrospective study included adult patients diagnosed with OSCC between January 2012 and December 2023. PD-L1 expression in tissue removed by definitive surgery was evaluated using immunohistochemistry, and tumor proportion score (TPS) and combined positive score (CPS) were calculated. Survival analyses were performed to assess its prognostic implications.</p><p><strong>Results: </strong>Among the 96 patients, TPS and CPS were 20% or above in 52 (54.2%) and 65 (67.7%) cases, respectively. TPS ≥20% was associated with mucosal lip location, earlier disease stage, and decreased risk of progression. The multivariate Cox regression model revealed that stage III/IV disease (HR: 2.176, 95%CI: 1.085-4.376, <i>p</i> = .029) and TPS ≥20% (HR: 0.241, 95%CI: 0.066-0.879, <i>p</i> = .031) were independent risk factors for progression-free survival.</p><p><strong>Conclusions: </strong>The study revealed that increased tumoral PD-L1 expression may reduce the risk of progression in patients with OSCC.</p><p><strong>Significance: </strong>These findings underscore the potential prognostic significance of PD-L1 expression in OSCC following surgical resection.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"648-653"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seasonality and climatic associations with deep neck space abscesses in Korea: a canonical correlation analysis. 季节性和气候与韩国深颈间隙脓肿的关联:典型相关分析。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-14 DOI: 10.1080/00016489.2025.2501602
Su Il Kim, Hun Hee Lee, Su Jin Kim, Young-Gyu Eun, Young Chan Lee
{"title":"Seasonality and climatic associations with deep neck space abscesses in Korea: a canonical correlation analysis.","authors":"Su Il Kim, Hun Hee Lee, Su Jin Kim, Young-Gyu Eun, Young Chan Lee","doi":"10.1080/00016489.2025.2501602","DOIUrl":"10.1080/00016489.2025.2501602","url":null,"abstract":"<p><strong>Background: </strong>Deep neck space abscesses are a significant medical issue, but their seasonality and climatic associations remain unclear.</p><p><strong>Objectives: </strong>This study aimed to examine the seasonality of deep neck space abscesses and identify associated climatic factors using a nationwide, population-based dataset.</p><p><strong>Material and methods: </strong>We utilized Korean National Health Insurance data (2010-2019) to identify patients with peritonsillar, retropharyngeal, and parapharyngeal abscesses (J36, J39.0, J39.1). Seasonality was assessed by calculating the ratio of the highest to lowest monthly incidence. Multivariate canonical correlation analysis (CCA) evaluated associations with climatic factors, including temperature, humidity, precipitation, sunlight, ground temperature, particulate matter (<10 µm), ultraviolet A dose, and daily temperature range.</p><p><strong>Results: </strong>The incidence of deep neck space abscesses peaked in winter and was lowest in summer, with seasonality ratios of 2.03 (peritonsillar) and 2.15 (retropharyngeal and parapharyngeal). CCA demonstrated a strong correlation between climatic factors and abscess incidence. The two canonical roots had high canonical coefficients R of 0.7996 and 0.5542, respectively (<i>p</i> < 0.0001 and <0.0001).</p><p><strong>Conclusion and significance: </strong>This large population-based study highlights the seasonality and climatic relevance of deep neck space abscesses. Further research is needed to explore demographic factors affecting incidence.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"661-668"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of environmental lighting on oculomotor tests results: a cross-sectional study. 环境照明对动眼力测试结果的影响:一项横断面研究。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-04 DOI: 10.1080/00016489.2025.2498401
Muhammed Pınar, Ayşenur Aykul Yağcıoğlu, Işılay Öz
{"title":"Effect of environmental lighting on oculomotor tests results: a cross-sectional study.","authors":"Muhammed Pınar, Ayşenur Aykul Yağcıoğlu, Işılay Öz","doi":"10.1080/00016489.2025.2498401","DOIUrl":"10.1080/00016489.2025.2498401","url":null,"abstract":"<p><strong>Background: </strong>Oculomotor tests (saccade, smooth pursuit and optokinetic test) are routinely used in clinical evaluations of the central vestibular system. There is no clear information about the lighting (light or dark) of the environment in which oculomotor tests are performed.</p><p><strong>Objectives: </strong>To determine optimum environment lighting by comparing oculomotor test results in bright and dark environments in healthy adults.</p><p><strong>Materials and methods: </strong>The study included 31 healthy adults aged between 18 and 30 without hearing or balance complaints. The participants were administered the Oculomotor tests in light and dark environments. Velocity, accuracy, and latency were compared in the saccade test, gain and asymmetry in the smooth pursuit test, and gain values in the optokinetic test.</p><p><strong>Results: </strong>The study found no statistically significant differences between light and dark environments in saccade, smooth pursuit, and optokinetic test (<i>p</i>> 0.05). However, the latency value determined, especially in the saccade test, was prolonged in the dark environment.</p><p><strong>Conclusions and significance: </strong>The minimal differences between the two environments obtained as a result of the study may lead to false negative results in patients with suspected central vestibular system pathology, making differential diagnosis difficult.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"627-632"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of endoscopic full-thickness cartilage-perichondrium complex tympanoplasty in the treatment of adhesive otitis media: a retrospective study. 内镜下全层软骨-软骨膜复合鼓室成形术治疗粘连性中耳炎的疗效回顾性研究。
IF 1.2 4区 医学
Acta Oto-Laryngologica Pub Date : 2025-07-01 Epub Date: 2025-05-08 DOI: 10.1080/00016489.2025.2501604
Miao Xie, Siyu Li, Rui Yang, Yuchen Zhou, Xia Gao, Maoli Duan, Ling Lu
{"title":"Efficacy of endoscopic full-thickness cartilage-perichondrium complex tympanoplasty in the treatment of adhesive otitis media: a retrospective study.","authors":"Miao Xie, Siyu Li, Rui Yang, Yuchen Zhou, Xia Gao, Maoli Duan, Ling Lu","doi":"10.1080/00016489.2025.2501604","DOIUrl":"10.1080/00016489.2025.2501604","url":null,"abstract":"<p><strong>Background: </strong>Adhesive otitis media (AdOM) is a common residual disease and surgical treatment for AdOM remains controversial.</p><p><strong>Objectives: </strong>The aims of present study are to investigate the feasibility and short-term effectiveness of endoscopic full-thickness cartilage-perichondrium complex tympanoplasty in the AdOM.</p><p><strong>Methods: </strong>This was a retrospective study on AdOM patients. Thirty-four patients were enrolled and followed for 1 year. Pure tone audiometry at pre and post-surgery were performed. The Chinese version of the chronic otitis media outcome test 15 (COMOT-15) was applied to assess symptoms of the patients.</p><p><strong>Results: </strong>All operated ears of the patients had dry ears at 1-year follow-up. The mean PTA decreased from 50.21 ± 11.08 to 37.06 ± 11.41 dB HL postoperatively (<i>p</i> < 0.0001), and the mean air-bone gap decreased from 24.85 ± 10.56 to 16.97 ± 7.68 dB HL postoperatively (<i>p</i> < 0.0001). Further, the average total score of COMOT-15 decreased from 30.56 ± 14.90 to 12.79 ± 12.53 postoperatively (<i>p</i> < 0.0001). The average symptomatic score of COMOT-15 decreased from 18.29 ± 9.23 to 7.38 ± 6.81 (<i>p</i> < 0.0001), and the average psychological score of COMOT-15 decreased from 12.24 ± 6.90 to 5.41 ± 6.19 respectively (<i>p</i> < 0.0001).</p><p><strong>Conclusions: </strong>Endoscopic full-thickness cartilage-perichondrium complex tympanoplasty is effective in treating AdOM. A prospective study is needed in the future.</p>","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"594-600"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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