Acta Oto-Laryngologica最新文献_第4页

Correction. 修正。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-03-28 DOI: 10.1080/00016489.2025.2485730

引用次数: 0

Differential diagnosis between pleomorphic adenoma and carcinoma ex pleomorphic adenoma: focus on clinical and MR findings. 多形性腺瘤与癌外多形性腺瘤的鉴别诊断：着重于临床和MR表现。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-09 DOI: 10.1080/00016489.2025.2480687

Asuka Sato, Tomoyasu Tachibana, Yuichiro Kanie, Minami Kakiuchi, Akifumi Kariya, Chieko Furukawa, Yuto Naoi, Yasuharu Sato, Mizuo Ando

{"title":"Differential diagnosis between pleomorphic adenoma and carcinoma ex pleomorphic adenoma: focus on clinical and MR findings.","authors":"Asuka Sato, Tomoyasu Tachibana, Yuichiro Kanie, Minami Kakiuchi, Akifumi Kariya, Chieko Furukawa, Yuto Naoi, Yasuharu Sato, Mizuo Ando","doi":"10.1080/00016489.2025.2480687","DOIUrl":"10.1080/00016489.2025.2480687","url":null,"abstract":"Background: In parotid tumors, preoperative differential diagnosis between pleomorphic adenoma (PA) and carcinoma ex pleomorphic adenoma (CXPA) remains challenging.Objectives: The present study aimed to evaluate the clinical characteristics of CXPA and PA and to identify factors associated with the differential diagnosis of these conditions.Material and methods: We reviewed the medical records of 6 CXPA and 127 PA patients treated surgically at our institution between 2008 and 2024.Result: Univariate analysis revealed significant differences in spontaneous pain (p = .044), facial nerve palsy (p = .045), and subjective enlargement (p < .01) between the CXPA and PA patients. Magnetic resonance imaging (MRI) revealed that the proportions of masses with ill-defined margins, localization in the deep lobe, and low apparent diffusion coefficient (ADC) were significantly higher in patients with CXPA than in those with PA (p < .01, p = .048, and p < .01, respectively). Multivariate analysis identified that spontaneous pain and masses with ill-defined margins were associated with CXPA (p = .047 and p = .013, respectively).Conclusion: Spontaneous pain and masses with ill-defined margins could be suggestive of CXPA rather than PA. Low ADC levels indicate the possibility of CXPA.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"540-544"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes of the cough reflex sensitivity following the septoplasty. 鼻中隔成形术后咳嗽反射敏感性的变化。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-23 DOI: 10.1080/00016489.2025.2488483

Miroslava Lucanska, Vladimir Calkovsky, Marian Grendar, Martina Neuschlova, Marek Samec, Peter Kunc, Renata Pecova

{"title":"Changes of the cough reflex sensitivity following the septoplasty.","authors":"Miroslava Lucanska, Vladimir Calkovsky, Marian Grendar, Martina Neuschlova, Marek Samec, Peter Kunc, Renata Pecova","doi":"10.1080/00016489.2025.2488483","DOIUrl":"10.1080/00016489.2025.2488483","url":null,"abstract":"Background: Doctors need information about cough reflex sensitivity influenced by symptomatic nasal septum deviation-the most common structural abnormality of the nasal cavity.Objectives: We assessed the relationship between cough reflex sensitivity and increased nasal patency caused by the deviation of nasal septum.Materials and methods: Eighteen adult patients (8 women and 10 men, age range 20-59 years, mean age 40.1 years) were included in the study. Capsaicin aerosol in doubling concentrations (from .49 to 1000 μmol/L) was inhaled by a single-breath method. We measured cough reflex sensitivity (C2, C5 values) before the septoplasty and 3 months after the septoplasty.Results: Patients cough reflex sensitivity before and after the septoplasty for C2 value was [21.25 (10.23-44.14) μmol/L vs. 57.85 (27.67-120.95) μmol/L] and for C5 value was [75.75 (31.56-181.80) μmol/l vs. 190.93 (109.46-333.02) μmol/L]. We have noticed statistically significant decrease of the cough reflex sensitivity after the septoplasty for both values (C2 and C5) (p = .001, p = .021).Conclusion and significance: Decreased nasal patency in patients after the septoplasty is related with decreased cough reflex sensitivity. Reduced cough reflex sensitivity after septoplasty is clinically significant, further research is needed to clarify the pathogenesis.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"512-514"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathologic features of chronic rhinosinusitis with nasal polyps in patients from high-altitude Xizang region. 西藏高海拔地区慢性鼻窦炎伴鼻息肉的组织病理学特征。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-17 DOI: 10.1080/00016489.2025.2485435

Yingqi Gao, Qianqian Zhang, Fuying Cheng, Chen Zhang, Le Shi, Jiani Chen, Yizhang Wang, Guoyu Cai, Sang Ge, Haiyue Zhang, Fan Shi, Zeng Dan, Zhuoma Ciwang, Huan Wang, Li Hu, Dehui Wang, Xicai Sun

{"title":"Histopathologic features of chronic rhinosinusitis with nasal polyps in patients from high-altitude Xizang region.","authors":"Yingqi Gao, Qianqian Zhang, Fuying Cheng, Chen Zhang, Le Shi, Jiani Chen, Yizhang Wang, Guoyu Cai, Sang Ge, Haiyue Zhang, Fan Shi, Zeng Dan, Zhuoma Ciwang, Huan Wang, Li Hu, Dehui Wang, Xicai Sun","doi":"10.1080/00016489.2025.2485435","DOIUrl":"10.1080/00016489.2025.2485435","url":null,"abstract":"Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease with varying patterns across regions.Objective: This study aims to investigate the clinical and histopathological features of CRSwNP in Xizang, a high-altitude region in China.Materials and methods: We retrospectively analyzed the histopathological features of CRSwNP patients from Shanghai and Xizang who underwent functional endoscopic sinus surgery (FESS) between 2017 and 2024. Polyp tissue samples were assessed, and statistical analyses compared features between the two regions in CRSwNP, eosinophilic CRSwNP (eCRSwNP), and noneosinophilic CRSwNP (neCRSwNP) patients.Results: Twenty-eight patients from Xizang and 35 from Shanghai were analyzed. All Shanghai patients were Han Chinese, and all Xizang patients were Tibetan. Compared to Shanghai, Tibetan patients had significantly lower rates of smoking and asthma. Overall inflammation levels in Xizang were lower, while eosinophil counts were lower in eCRSwNP patients. Neutrophil infiltration, mucosal ulceration, and squamous metaplasia were higher in Xizang patients, while neCRSwNP patients exhibited more neutrophil infiltration and less subepithelial edema.Conclusions: The study revealed that Tibetan patients with CRSwNP have lower eosinophilic inflammation but higher neutrophil infiltration and squamous metaplasia compared to Shanghai patients, indicating the impact of high-altitude environments on inflammatory patterns.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"506-511"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Auditory neurophysiological characteristics in unilateral deafness: influence of deafness side. 单侧耳聋听觉神经生理特征：耳聋侧的影响。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-09 DOI: 10.1080/00016489.2025.2487641

Seval Ceylan, Şule Çekiç

{"title":"Auditory neurophysiological characteristics in unilateral deafness: influence of deafness side.","authors":"Seval Ceylan, Şule Çekiç","doi":"10.1080/00016489.2025.2487641","DOIUrl":"10.1080/00016489.2025.2487641","url":null,"abstract":"Background: The characteristics of auditory processing and reorganization after unilateral deafness remain unclear.Aims/objectives: This study aimed to examine subcortical and cortical auditory neurophysiological features in young adults with unilateral deafness according to the side of deafness.Methods: Patient group: A total of 27 men (25.93- ± 3.64-year old) with unilateral deafness [15 right-sided and 12 left-sided deafness (L-SD)] were included. Twenty-one adult males (29.90 ± 3.05 years) with normal bilateral hearing were included in the Normal Control group. Neurodiagnostic Auditory Brainstem Responses (ABR) and Cortical Auditory Evoked Potentials (CAEP) tests were performed on all participants. ABR and CAEP results were compared between groups.Results: In the right-sided deafness (R-SD) group, ABR wave V amplitudes (left ear) were higher than the control group, and the III-V interpeak latencies were found to be shorter (p = .007, p = .032, respectively). In the L-SD group: CAEP wave P1N1 and N1P2 amplitudes were higher than in the R-SD group (p = .037, p = .015, respectively).Conclusions and significance: Auditory neurophysiological biomarkers in adults with unilateral deafness differ according to the side of the deafness. The results of this study may provide preliminary information for the development of appropriate rehabilitation methods according to the deafness side after single-sided deafness.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"483-490"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

C1QL1 regulates auditory nerve fibers growth via ELMO1-DOCK180-RAC1 integrin. C1QL1通过ELMO1-DOCK180-RAC1整合素调控听神经纤维生长。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-07 DOI: 10.1080/00016489.2025.2486613

Minglin Chen, Yue Qi, Shusheng Gong

{"title":"C1QL1 regulates auditory nerve fibers growth via ELMO1-DOCK180-RAC1 integrin.","authors":"Minglin Chen, Yue Qi, Shusheng Gong","doi":"10.1080/00016489.2025.2486613","DOIUrl":"10.1080/00016489.2025.2486613","url":null,"abstract":"Background: Complement C1q Like 1 (C1QL1), a secreted protein, is known to play an important role in synaptic maturation, regulation, and maintenance in central nervous system. C1QL1 is expressed in adult cochlea inner and outer hair cells. However, the mechanism of C1QL1 in cochlea remains unclear.Objective: This study aims to reveal the mechanism of C1ql1 gene in cochlea, including its target and pathway.Material and methods: The protein-protein interaction analysis of C1QL1 was conducted with STRING database. The interaction between C1QL1 and BAI3 in cochlea was further confirmed by colocalization and co-immunoprecipitation. via upregulating and downregulating the expression of C1ql1, the factors in the pathway can be detected.Results: C1QL1 protein interacts with BAI3 protein in cochlea. C1ql1 overexpression had no effect on auditory phenotype. C1ql1 regulates auditory nerve fibers growth via BAI3 and ELMO1-DOCK180-RAC1 integrin. Meanwhile, C1ql1 overexpression inhibited the expression of TIAM1-PARD3 integrin.Conclusions and significance: C1QL1 interacts with BAI3 in cochlea and C1ql1 regulates auditory nerve fibers growth via ELMO1-DOCK180-RAC1 integrin. C1ql1 overexpression can inhibit the expression of TIAM1-PARD3 integrin.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"476-482"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical outcomes and prognostic indicators in parotid gland carcinomas: a single-center experience. 腮腺癌的临床结果和预后指标：单中心经验。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-17 DOI: 10.1080/00016489.2025.2490294

Ergin Eroğlu, Erim Pamuk, Yaşar Enez Bilen, Oğuz Kuşcu

{"title":"Clinical outcomes and prognostic indicators in parotid gland carcinomas: a single-center experience.","authors":"Ergin Eroğlu, Erim Pamuk, Yaşar Enez Bilen, Oğuz Kuşcu","doi":"10.1080/00016489.2025.2490294","DOIUrl":"10.1080/00016489.2025.2490294","url":null,"abstract":"Background: Parotid gland cancers (PGC) are a heterogeneous group with different histological types and grades. This difference has implications for patient management and adjuvant treatment decisions.Objective: This study aims to determine the poor prognostic factors affecting local control and survival in PGC.Materials and methods: A retrospective review of 42 patients treated for malignant parotid masses between January 2008 and December 2023. Risk factors analyzed included sex, age, histological grade, tumor size, stage, nodal involvement, perineural invasion (PNI), surgical margins, and additional treatments.Results: Of the 42 patients, 47.6% were male, and the median age was 44 years. The 5-year local relapse-free survival (LRFS) was 69.7%. Positive surgical margins significantly associated with lower LRFS rate (p = .007). The 5-year disease-specific survival (DSS) was 83.9%, with surgical margin and T stage being significant prognostic factors (0.044 and 0.031, respectively). Advanced T stage was associated with a higher rate of preoperative facial nerve dysfunction (p = .004).Conclusions and significance: This study underscores the critical role of comprehensive diagnostic and individualized surgical strategies in the treatment of parotid gland malignancies.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"554-560"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The expression and significance of nasal mucosal glandular hyperplasia and eosinophil infiltration in chronic rhinosinusitis. 慢性鼻窦炎鼻黏膜腺增生及嗜酸性粒细胞浸润的表达及意义。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-16 DOI: 10.1080/00016489.2025.2489644

Minman Wu, Bowen Qiu, Ying Xu, Yuaner Mao, Yizuo Qubi, Xiyu Zhao, Guanggui Qin, Xiaoxuan Du

{"title":"The expression and significance of nasal mucosal glandular hyperplasia and eosinophil infiltration in chronic rhinosinusitis.","authors":"Minman Wu, Bowen Qiu, Ying Xu, Yuaner Mao, Yizuo Qubi, Xiyu Zhao, Guanggui Qin, Xiaoxuan Du","doi":"10.1080/00016489.2025.2489644","DOIUrl":"10.1080/00016489.2025.2489644","url":null,"abstract":"Background: The pathophysiological mechanisms underlying nasal mucosal glandular changes in chronic rhinosinusitis (CRS) remains poorly understood.Objectives: This study aimed to examine nasal mucosal glandular density and eosinophil (Eos) infiltration in CRS patients and their role in disease pathogenesis.Materials and methods: HE staining was used to assess glandular density and Eos infiltration in nasal mucosal lesion tissues from 86 CRS patients during FESS (16 CRS without nasal polyps (CRSsNP), 55 non-eosinophilic CRS with nasal polyps (nECRSwNP), and 15 eosinophilic CRSwNP (ECRSwNP)). Immunohistochemical analysis was conducted to evaluate eosinophil cationic protein (ECP), lysozyme, and immunoglobulin A (IgA) expression within these tissues. The Kruskal-Wallis test was used to reveal the statistical difference in therapeutic efficacy among the groups.Results: The CRSsNP group showed nasal mucosal glandular density of '+++/++' with minimal Eos infiltration, and 94% achieved control. The nECRSwNP group exhibited atypical glandular hyperplasia and Eos infiltration, with 22% achieving complete control, 51% partial control, and 27% no control. The ECRSwNP group had significant Eos infiltration '++/+++' and reduced glands, with 93% showing uncontrolled conditions.Conclusions and significance: The findings suggest that extensive Eos infiltration and ECP secretion contribute to glandular and epithelial damage, reducing lysozyme and IgA production. These changes may promote chronic inflammation and increase the likelihood of nasal polyp recurrence.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"522-527"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation between periostin and eosinophillic cationic protein demonstrate its potential biomarker of mucosal remodeling in chronic rhinosinusitis with nasal polyps. 骨膜蛋白与嗜酸性阳离子蛋白之间的相关性表明其可能是慢性鼻窦炎伴鼻息肉患者粘膜重塑的生物标志物。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-21 DOI: 10.1080/00016489.2025.2486615

Iriana Maharani, Loeki Enggar Fitri, Susanthy Djajalaksana, Edi Handoko, Yudha Adi Pradana

{"title":"The correlation between periostin and eosinophillic cationic protein demonstrate its potential biomarker of mucosal remodeling in chronic rhinosinusitis with nasal polyps.","authors":"Iriana Maharani, Loeki Enggar Fitri, Susanthy Djajalaksana, Edi Handoko, Yudha Adi Pradana","doi":"10.1080/00016489.2025.2486615","DOIUrl":"10.1080/00016489.2025.2486615","url":null,"abstract":"Introduction: Chronic rhinosinusitis (CRS) is classified into CRS with nasal polyps (CRSwNP), a type 2 inflammation with elevated CLC and ECP levels, and CRS without nasal polyps (CRSsNP), a non-type 2 inflammation. Periostin plays a crucial role in mucosal remodeling, but its involvement in CRSwNP remains unclear.Aims/objectives: To investigate correlation between CRSwNP endotype and periostin levels.Materials and methods: This cross-sectional study measured endotype biomarkers (ECP, CLC, IFN-γ, IL-17A) and periostin levels in uncinate process and nasal polyps using ELISA to assess their correlation.Results: 99.6% of uncinate process and 36.67% of nasal polyp tissue samples displayed a mixed endotype pattern, while 2 samples were untype-able. Periostin levels were significantly higher in nasal polyp compared to uncinate process tissue (p = .0116) and control. Only ECP levels in the uncinate process showed a significant correlation with periostin (r = 0.326, p = .038).Conclusion and significance: Periostin is significantly elevated in nasal polyps, highlighting its role in CRSwNP. Its correlation with ECP in the uncinate process suggests involvement in inflammation, warranting further research into periostin as a therapeutic target. This study confirms periostin's role in CRSwNP, it potentially occurs with or without depending on the CRS endotype pathways.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"515-521"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revision of the Turkish Khalfa Hyperacusis Questionnaire: a boosted tool for the tinnitus population. 土耳其Khalfa耳鸣调查问卷的修订：耳鸣人群的增强工具。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-06-01 Epub Date: 2025-04-08 DOI: 10.1080/00016489.2025.2485438

Nazife Öztürk Özdeş, Gizem Kır, Suna Tokgöz-Yılmaz

{"title":"Revision of the Turkish Khalfa Hyperacusis Questionnaire: a boosted tool for the tinnitus population.","authors":"Nazife Öztürk Özdeş, Gizem Kır, Suna Tokgöz-Yılmaz","doi":"10.1080/00016489.2025.2485438","DOIUrl":"10.1080/00016489.2025.2485438","url":null,"abstract":"Background: Due to low factor loadings and problems with construct validity of the current version of the Turkish Khalfa Hyperacusis Questionnaire, there is a need for a revision that can more accurately assess hyperacusis in individuals with tinnitus.Objective: The main aim of this study was to re-evaluate the Khalfa Hyperacusis Questionnaire for individuals with tinnitus and to analyze its reliability and validity.Materials and methods: The new version of Khalfa Hyperacusis Questionnaire (HQ-R), consisting of 12 items, was tested on 269 participants with tinnitus and the suitability of the two-factor structure was evaluated by Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA).Results: EFA revealed that the scale explained 60.247% of the total variability and the factor loadings were strong. It was determined that the CFA model provided an excellent fit. The CA value of the instrument was found to be 0.908 and a high level of reliability was obtained. The cut-off score was 14 and this value was used to accurately classify hyperacusis.Conclusion: The HQ-R provides a measurement tool that can more precisely and accurately assess hyperacusis in individuals with tinnitus. The improvements will be an important resource for clinicians and researchers working with tinnitus patients.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"499-505"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0