Acta Oto-Laryngologica最新文献_第4页

Auditory and cognitive abilities in patients with chronic kidney disease: a comparative study across stages. 慢性肾脏疾病患者的听觉和认知能力：一项跨阶段的比较研究

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-22 DOI: 10.1080/00016489.2025.2489665

Tuana Saglanmak, Aysenur Kucuk Ceyhan

{"title":"Auditory and cognitive abilities in patients with chronic kidney disease: a comparative study across stages.","authors":"Tuana Saglanmak, Aysenur Kucuk Ceyhan","doi":"10.1080/00016489.2025.2489665","DOIUrl":"https://doi.org/10.1080/00016489.2025.2489665","url":null,"abstract":"Background: The impact of chronic kidney disease (CKD) on peripheral hearing is well documented, but little is known about the impact on auditory processing.Aim: This study aimed to evaluate auditory processing and cognitive abilities in CKD and to assess changes according to the disease phases.Materials and methods: Eighty-nine CKD patients, aged 25-65 (48 study and 41 control) with stages 2-4, participated. Random Gap Detection Test (RGDT), Frequency Pattern Test (FPT), Duration Pattern Test (DPT), the Digit Span Backward Task (DSBT) and the speech discrimination (SD) in noise and in quiet test were employed.Results: The comparison between the two groups indicated significant decreases in test scores for the RGDT, FPT, DPT, DSBT, and SD (in noise) within in the group with CKD (p < .001). The SD (in quiet) test exhibits no difference. There were no significant variations in any evaluated parameter between CKD stages.Conclusions and significance: The results indicate that CKD can impair auditory and cognitive processing, hence affecting SD, especially in challenging auditory environments. Nevertheless, no significant changes were observed across the phases of CKD, suggesting that impairments in these capacities may appear early in the course of the disease.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-5"},"PeriodicalIF":1.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Diagnostics and management of submandibular space schwannoma: a systematic review. 目前的诊断和治疗下颌间隙神经鞘瘤：一个系统的回顾。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-22 DOI: 10.1080/00016489.2025.2486611

Srivatsa Surya Vasudevan, Estephania Candelo, Anyull D Bohorquez Caballero, Katerina J Green, Tiba Yamin Kandrikar, Jeffrey R Janus

{"title":"Current Diagnostics and management of submandibular space schwannoma: a systematic review.","authors":"Srivatsa Surya Vasudevan, Estephania Candelo, Anyull D Bohorquez Caballero, Katerina J Green, Tiba Yamin Kandrikar, Jeffrey R Janus","doi":"10.1080/00016489.2025.2486611","DOIUrl":"https://doi.org/10.1080/00016489.2025.2486611","url":null,"abstract":"Background: Submandibular space schwannomas (SSS) are rare tumors originating from the neural sheath in the submandibular region with varied prognoses.Objective: The primary objective was to evaluate the current diagnostic and management outcomes of SSS.Material and methods: PubMed, Embase, Science Direct, and Web of Science were reviewed for articles from inception through January 2025. Fisher's test was used to calculate the difference in outcomes between extraglandular (EG) and intraglandular (IG) subtypes.Results: A total of 44 studies with 47 patients were included with a mean age (SD) of 42.8 (19.3) years. Hypoglossal nerve (43.3%) and lingual nerve (36.6%) were the primary nerve of origin for SSS, with significantly higher rates of hypoglossal nerve origin in EG-SSS than IG-SSS (p = .008). Sensitivity analysis of preoperative biopsy showed higher sensitivity rates with core biopsy compared to fine-needle aspiration cytology (FNAC) (85.7% vs. 38.7%) in SSS diagnosis. IG schwannomas are more likely to undergo submandibular gland excision (p = .002) than EG schwannoma.Conclusion: Core biopsy demonstrated superior sensitivity compared to FNAC, establishing it as the preferred diagnostic tool. The hypoglossal nerve was the most identified nerve of origin.Significance: This review offers a comprehensive insight into the preoperative and perioperative management of SSS subtypes for surgeon decisions.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation between periostin and eosinophillic cationic protein demonstrate its potential biomarker of mucosal remodeling in chronic rhinosinusitis with nasal polyps. 骨膜蛋白与嗜酸性阳离子蛋白之间的相关性表明其可能是慢性鼻窦炎伴鼻息肉患者粘膜重塑的生物标志物。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-21 DOI: 10.1080/00016489.2025.2486615

Iriana Maharani, Loeki Enggar Fitri, Susanthy Djajalaksana, Edi Handoko, Yudha Adi Pradana

{"title":"The correlation between periostin and eosinophillic cationic protein demonstrate its potential biomarker of mucosal remodeling in chronic rhinosinusitis with nasal polyps.","authors":"Iriana Maharani, Loeki Enggar Fitri, Susanthy Djajalaksana, Edi Handoko, Yudha Adi Pradana","doi":"10.1080/00016489.2025.2486615","DOIUrl":"https://doi.org/10.1080/00016489.2025.2486615","url":null,"abstract":"Introduction: Chronic rhinosinusitis (CRS) is classified into CRS with nasal polyps (CRSwNP), a type 2 inflammation with elevated CLC and ECP levels, and CRS without nasal polyps (CRSsNP), a non-type 2 inflammation. Periostin plays a crucial role in mucosal remodeling, but its involvement in CRSwNP remains unclear.Aims/objectives: To investigate correlation between CRSwNP endotype and periostin levels.Materials and methods: This cross-sectional study measured endotype biomarkers (ECP, CLC, IFN-γ, IL-17A) and periostin levels in uncinate process and nasal polyps using ELISA to assess their correlation.Results: 99.6% of uncinate process and 36.67% of nasal polyp tissue samples displayed a mixed endotype pattern, while 2 samples were untype-able. Periostin levels were significantly higher in nasal polyp compared to uncinate process tissue (p = .0116) and control. Only ECP levels in the uncinate process showed a significant correlation with periostin (r = 0.326, p = .038).Conclusion and significance: Periostin is significantly elevated in nasal polyps, highlighting its role in CRSwNP. Its correlation with ECP in the uncinate process suggests involvement in inflammation, warranting further research into periostin as a therapeutic target. This study confirms periostin's role in CRSwNP, it potentially occurs with or without depending on the CRS endotype pathways.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathologic features of chronic rhinosinusitis with nasal polyps in patients from high-altitude Xizang region. 西藏高海拔地区慢性鼻窦炎伴鼻息肉的组织病理学特征。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-17 DOI: 10.1080/00016489.2025.2485435

Yingqi Gao, Qianqian Zhang, Fuying Cheng, Chen Zhang, Le Shi, Jiani Chen, Yizhang Wang, Guoyu Cai, Sang Ge, Haiyue Zhang, Fan Shi, Zeng Dan, Zhuoma Ciwang, Huan Wang, Li Hu, Dehui Wang, Xicai Sun

{"title":"Histopathologic features of chronic rhinosinusitis with nasal polyps in patients from high-altitude Xizang region.","authors":"Yingqi Gao, Qianqian Zhang, Fuying Cheng, Chen Zhang, Le Shi, Jiani Chen, Yizhang Wang, Guoyu Cai, Sang Ge, Haiyue Zhang, Fan Shi, Zeng Dan, Zhuoma Ciwang, Huan Wang, Li Hu, Dehui Wang, Xicai Sun","doi":"10.1080/00016489.2025.2485435","DOIUrl":"https://doi.org/10.1080/00016489.2025.2485435","url":null,"abstract":"Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease with varying patterns across regions.Objective: This study aims to investigate the clinical and histopathological features of CRSwNP in Xizang, a high-altitude region in China.Materials and methods: We retrospectively analyzed the histopathological features of CRSwNP patients from Shanghai and Xizang who underwent functional endoscopic sinus surgery (FESS) between 2017 and 2024. Polyp tissue samples were assessed, and statistical analyses compared features between the two regions in CRSwNP, eosinophilic CRSwNP (eCRSwNP), and noneosinophilic CRSwNP (neCRSwNP) patients.Results: Twenty-eight patients from Xizang and 35 from Shanghai were analyzed. All Shanghai patients were Han Chinese, and all Xizang patients were Tibetan. Compared to Shanghai, Tibetan patients had significantly lower rates of smoking and asthma. Overall inflammation levels in Xizang were lower, while eosinophil counts were lower in eCRSwNP patients. Neutrophil infiltration, mucosal ulceration, and squamous metaplasia were higher in Xizang patients, while neCRSwNP patients exhibited more neutrophil infiltration and less subepithelial edema.Conclusions: The study revealed that Tibetan patients with CRSwNP have lower eosinophilic inflammation but higher neutrophil infiltration and squamous metaplasia compared to Shanghai patients, indicating the impact of high-altitude environments on inflammatory patterns.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical outcomes and prognostic indicators in parotid gland carcinomas: a single-center experience. 腮腺癌的临床结果和预后指标：单中心经验。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-17 DOI: 10.1080/00016489.2025.2490294

Ergin Eroğlu, Erim Pamuk, Yaşar Enez Bilen, Oğuz Kuşcu

{"title":"Clinical outcomes and prognostic indicators in parotid gland carcinomas: a single-center experience.","authors":"Ergin Eroğlu, Erim Pamuk, Yaşar Enez Bilen, Oğuz Kuşcu","doi":"10.1080/00016489.2025.2490294","DOIUrl":"https://doi.org/10.1080/00016489.2025.2490294","url":null,"abstract":"Background: Parotid gland cancers (PGC) are a heterogeneous group with different histological types and grades. This difference has implications for patient management and adjuvant treatment decisions.Objective: This study aims to determine the poor prognostic factors affecting local control and survival in PGC.Materials and methods: A retrospective review of 42 patients treated for malignant parotid masses between January 2008 and December 2023. Risk factors analyzed included sex, age, histological grade, tumor size, stage, nodal involvement, perineural invasion (PNI), surgical margins, and additional treatments.Results: Of the 42 patients, 47.6% were male, and the median age was 44 years. The 5-year local relapse-free survival (LRFS) was 69.7%. Positive surgical margins significantly associated with lower LRFS rate (p = .007). The 5-year disease-specific survival (DSS) was 83.9%, with surgical margin and T stage being significant prognostic factors (0.044 and 0.031, respectively). Advanced T stage was associated with a higher rate of preoperative facial nerve dysfunction (p = .004).Conclusions and significance: This study underscores the critical role of comprehensive diagnostic and individualized surgical strategies in the treatment of parotid gland malignancies.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcutaneous laryngeal ultrasound for long-term voice function and vocal fold evaluation after thyroidectomy: a prospective study. 经皮喉超声对甲状腺切除术后长期语音功能和声带评价的前瞻性研究。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-16 DOI: 10.1080/00016489.2025.2484792

Dan Gao, Li Yang, Yuling Duan, Yongyi Li, Chen Chen

{"title":"Transcutaneous laryngeal ultrasound for long-term voice function and vocal fold evaluation after thyroidectomy: a prospective study.","authors":"Dan Gao, Li Yang, Yuling Duan, Yongyi Li, Chen Chen","doi":"10.1080/00016489.2025.2484792","DOIUrl":"https://doi.org/10.1080/00016489.2025.2484792","url":null,"abstract":"Background: Transcutaneous laryngeal ultrasound (TLUSG) has come up as a practical alternative to laryngoscopy for the diagnosis of vocal fold palsy (VFP), as it's non-invasive and capable for dynamic real-time evaluation.Aims/objectives: To assess the features of the vocal cord (VF) recovery process and the diagnostic significance of TLUSG for VFP during long-term follow-up on patients with voice disorders post-thyroidectomy.Material and methods: Fifty-seven patients with voice impairment following thyroidectomy were enrolled. The image features of VFs and the voice handicap index (VHI) scores were recorded at various intervals after surgery. Laryngoscopy was performed for comparison.Results: 75.4%(43/57) patients recovered voice function as assessed by VHI, 41 (71.9%) patients demonstrated recovery by TLUSG. Eighteen patients underwent laryngoscopy, and 14 were identified as VFP. The ultrasonic images of VFP presented with different manifestations at different periods after thyroidectomy. The diagnostic accuracy of TLUSG increased from 77.8% to 88.9% over time, whereas that of VHI exhibited a decrease. TLUSG and Laryngoscope were highly consistent (κ = 0.679), as were the evaluations of two physicians.Conclusions and significance: The TLUSG is an effective alternative to laryngoscopy in patients with vocal dysfunction following thyroidectomy.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic hearing thresholds after glycerol ingestion may be modified by endolymphatic hydrops status in Ménière's disease. 摄入甘油后的动态听力阈值可能会因内淋巴积液状态而改变。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-16 DOI: 10.1080/00016489.2025.2489646

Hui Pan, Ping Lei, Qin Liu, Yingzhao Liu, Kaijun Xia, Xingqian Shen, Xiaoye Chen, Ziying Xu, Wenliang Fan, Yangming Leng, Bo Liu

{"title":"Dynamic hearing thresholds after glycerol ingestion may be modified by endolymphatic hydrops status in Ménière's disease.","authors":"Hui Pan, Ping Lei, Qin Liu, Yingzhao Liu, Kaijun Xia, Xingqian Shen, Xiaoye Chen, Ziying Xu, Wenliang Fan, Yangming Leng, Bo Liu","doi":"10.1080/00016489.2025.2489646","DOIUrl":"https://doi.org/10.1080/00016489.2025.2489646","url":null,"abstract":"Background: Endolymphatic hydrops (ELH) can be identified by electrophysiological and radiological examinations.Objectives: We aimed to investigate the relationship between audiometric glycerol test and delayed magnetic resonance imaging (MRI) of the inner ear after intratympanic gadolinium in patients with unilateral Ménière's disease (MD).Material and methods: Forty-two patients with unilateral definite MD underwent audiometric glycerol test and delayed MRI following intratympanic gadolinium application.Results: The degree of cochlear ELH was moderately positively correlated with the mean hearing threshold below 2 kHz. For those ears with positive glycerol results, the best hearing threshold was measured at 3 h and the maximal improvement of hearing threshold was observed within the third hour. The overall positive rates of glycerol test did not differ between ELH (+) and ELH (-) subgroups based on the MRI findings. Significant temporal changes in the positive rate were only observed in the ELH (+) subgroup. The rebound rate did not change significantly over time in either subgroup.Conclusions and significance: In MD patients, glycerol-induced dynamic shift of hearing threshold may be modified by the hydropic status of the inner ear. For those without radiological ELH, glycerol test could be used as additional diagnostic tool to detect hydrops.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The expression and significance of nasal mucosal glandular hyperplasia and eosinophil infiltration in chronic rhinosinusitis. 慢性鼻窦炎鼻黏膜腺增生及嗜酸性粒细胞浸润的表达及意义。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-16 DOI: 10.1080/00016489.2025.2489644

Minman Wu, Bowen Qiu, Ying Xu, Yuaner Mao, Yizuo Qubi, Xiyu Zhao, Guanggui Qin, Xiaoxuan Du

{"title":"The expression and significance of nasal mucosal glandular hyperplasia and eosinophil infiltration in chronic rhinosinusitis.","authors":"Minman Wu, Bowen Qiu, Ying Xu, Yuaner Mao, Yizuo Qubi, Xiyu Zhao, Guanggui Qin, Xiaoxuan Du","doi":"10.1080/00016489.2025.2489644","DOIUrl":"https://doi.org/10.1080/00016489.2025.2489644","url":null,"abstract":"Background: The pathophysiological mechanisms underlying nasal mucosal glandular changes in chronic rhinosinusitis (CRS) remains poorly understood.Objectives: This study aimed to examine nasal mucosal glandular density and eosinophil (Eos) infiltration in CRS patients and their role in disease pathogenesis.Materials and methods: HE staining was used to assess glandular density and Eos infiltration in nasal mucosal lesion tissues from 86 CRS patients during FESS (16 CRS without nasal polyps (CRSsNP), 55 non-eosinophilic CRS with nasal polyps (nECRSwNP), and 15 eosinophilic CRSwNP (ECRSwNP)). Immunohistochemical analysis was conducted to evaluate eosinophil cationic protein (ECP), lysozyme, and immunoglobulin A (IgA) expression within these tissues. The Kruskal-Wallis test was used to reveal the statistical difference in therapeutic efficacy among the groups.Results: The CRSsNP group showed nasal mucosal glandular density of '+++/++' with minimal Eos infiltration, and 94% achieved control. The nECRSwNP group exhibited atypical glandular hyperplasia and Eos infiltration, with 22% achieving complete control, 51% partial control, and 27% no control. The ECRSwNP group had significant Eos infiltration '++/+++' and reduced glands, with 93% showing uncontrolled conditions.Conclusions and significance: The findings suggest that extensive Eos infiltration and ECP secretion contribute to glandular and epithelial damage, reducing lysozyme and IgA production. These changes may promote chronic inflammation and increase the likelihood of nasal polyp recurrence.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the role of vestibular function in motion sickness and visually induced motion sickness by multiple vestibular function tests. 通过多次前庭功能试验探讨前庭功能在晕动病和视动病中的作用。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-16 DOI: 10.1080/00016489.2025.2486609

Jing Zhao, Linyao Shi, Xiaoming Li, Chuanxia Cao, Qikun Zhang, Chuanjing Qiu, Jiamei Lu, Shuai Pan, Jing Xue, Zhanguo Jin, Shengguang Yan

{"title":"Investigating the role of vestibular function in motion sickness and visually induced motion sickness by multiple vestibular function tests.","authors":"Jing Zhao, Linyao Shi, Xiaoming Li, Chuanxia Cao, Qikun Zhang, Chuanjing Qiu, Jiamei Lu, Shuai Pan, Jing Xue, Zhanguo Jin, Shengguang Yan","doi":"10.1080/00016489.2025.2486609","DOIUrl":"https://doi.org/10.1080/00016489.2025.2486609","url":null,"abstract":"Background: Motion sickness (MS) and visually induced motion sickness (VIMS) are vestibular system-related conditions affecting balance.Objectives: To investigate the role of vestibular function and susceptibility in MS/VIMS in healthy college students and to evaluate the effectiveness of various vestibular function tests in detecting these disorders.Materials and methods: Five hundred young adults, grouped by motion sickness susceptibility questionnaire-short (MSSQ-S) and visually induced motion sickness susceptibility questionnaire-short (VIMSSQ-S) questionnaires, were further analyzed via continuous linear regression to validate the grouping strategy. The participants completed a caloric test (CT), video head impulse test (vHIT), dynamic visual acuity (DVA), subjective visual vertical/horizontal (SVV/SVH), and sensory organisation tests (SOT). Analysis of the relationship between the results of the five tests and the MS/VIMS.Results: CT revealed significant differences in right cold slow-phase velocity (RC SPV) and left cold slow-phase velocity (LC SPV) among groups (p < 0.001), with strong correlations between these values and MS/VIMS susceptibility (p < 0.05). Among 52 subjects with abnormal CT results, significant differences were found in vHIT, DVA, and SOT (p < 0.001), while SVV/SVH showed a significant difference only in MSSQ-S scores (p = 0.034).Conclusions and significance: This study comprehensively assessed vestibular function in MS and VIMS susceptible individuals, confirming increased sensitivity and highlighting the need for targeted evaluation strategies.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-10"},"PeriodicalIF":1.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of factors affecting the efficacy of bilateral posterior semicircular canal occlusion in the treatment of refractory benign paroxysmal positional vertigo. 影响双侧后半规管闭塞治疗难治性良性阵发性位置性眩晕疗效的因素分析。

IF 1.2 4区医学

Acta Oto-Laryngologica Pub Date : 2025-04-16 DOI: 10.1080/00016489.2025.2490296

Hui Yong, Lingling Di, Zhikai Wang, Jing Kang, Pei Yang, Xiaoping Gao

{"title":"Analysis of factors affecting the efficacy of bilateral posterior semicircular canal occlusion in the treatment of refractory benign paroxysmal positional vertigo.","authors":"Hui Yong, Lingling Di, Zhikai Wang, Jing Kang, Pei Yang, Xiaoping Gao","doi":"10.1080/00016489.2025.2490296","DOIUrl":"https://doi.org/10.1080/00016489.2025.2490296","url":null,"abstract":"Background: Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder. Refractory cases persist despite ≥3 repositioning maneuvers over 6 months.Objective: To identify factors influencing bilateral posterior semicircular canal occlusion (BPCO) efficacy in refractory BPPV.Methods: A retrospective study included 120 refractory BPPV patients undergoing BPCO. Patients were divided into Group A (successful outcomes, n = 84) and Group B (suboptimal outcomes, n = 36) based on postoperative DHI reduction (≥50% vs. <50%).Results: Group B had a higher mean age (69.85 ± 4.15 vs. 62.28 ± 3.64 years, p =.012), longer disease duration (≥1 year: 30.56% vs. 10.73%, p < .01), and more bilateral BPPV (16.67% vs. 5.96%, p < .01). At 6 months, Group B showed poorer outcomes: higher dizziness handicap inventory (DHI) scores (53.24 ± 5.39 vs. 30.11 ± 2.88), lower SF-36 scores (58.10 ± 5.32 vs. 81.45 ± 6.29), higher recurrence rates (38.89% vs. 7.14%), and more frequent attacks (13.75 ± 3.66 vs. 4.36 ± 1.25/month) (p < .05). Multivariate analysis confirmed age, disease duration, and bilateral BPPV as independent risk factors (p < .01).Conclusions: Older age (≥65 years), prolonged disease duration (≥1 year), and bilateral BPPV predict poor BPCO outcomes in refractory BPPV. These factors are critical for preoperative decision-making.","PeriodicalId":6880,"journal":{"name":"Acta Oto-Laryngologica","volume":" ","pages":"1-6"},"PeriodicalIF":1.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0