{"title":"Linked lives: Dyadic trajectories of cognitive function among middle-aged and older couples.","authors":"Dexia Kong, Xiaomin Li, Yaxin Lan, Emma Zang","doi":"10.1093/geronb/gbaf063","DOIUrl":"https://doi.org/10.1093/geronb/gbaf063","url":null,"abstract":"<p><strong>Objectives: </strong>Our study is among the first to analyze the developmental trajectories of cognitive function at the couple level.</p><p><strong>Methods: </strong>Using longitudinal dyadic data obtained from 2,130 heterosexual couples who participated in the China Health and Retirement Longitudinal Study between 2011 and 2020, we employed the dyadic latent growth curve model to analyze the developmental trajectories of wives' and husbands' cognitive function from 2011 to 2018. We examined the significant predictors of membership of the latent profiles, as well as the extent to which membership of the latent profiles predicted husbands' and wives' depressive symptoms at follow-up (i.e., in 2018 and 2020).</p><p><strong>Results: </strong>The two identified dyadic profiles reflected distinct developmental trajectories at the couple level: high stable couples with outperforming husbands (Profile 1, 81.6% of couples), and moderate stable wives-moderate rapid decline husbands (Profile 2, 18.4% of couples). Husbands' older age and higher number of functional limitations, and couples' residence in rural areas at baseline predicted a higher likelihood of membership in Profile 2. Husbands reporting more chronic conditions at baseline predicted a lower likelihood of the couple being classified in Profile 2. Couples in Profile 2 exhibited higher levels of depression symptoms than their counterparts in Profile 1 in 2018 and 2020.</p><p><strong>Discussion: </strong>Our results highlight the utility of a couple approach in analyzing the developmental trajectories of cognitive functioning in later life and advance our understanding of how couple-level changes exert influence on both spouses' mental health.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Collin W Mueller, Carlos D Tavares, Katrina M Walsemann
{"title":"Cohort Differences in Perceived Discrimination Trajectories among Aging Black Americans.","authors":"Collin W Mueller, Carlos D Tavares, Katrina M Walsemann","doi":"10.1093/geronb/gbaf077","DOIUrl":"https://doi.org/10.1093/geronb/gbaf077","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines how later-life perceptions of everyday discrimination vary as a function of cohort-level differences in exposure to three distinct racialized social systems across historical time (i.e., whether individuals experienced childhood and early adolescence during the Pre-Brown v Board Era, Protest Era, or Colorblind Era).</p><p><strong>Methods: </strong>We used the Health and Retirement Study to estimate age-specific trajectories in 5-item Everyday Discrimination Scale (EDS-5) scores and counts of discriminatory situations among aging Black Americans. We then examined the likelihood of trajectory group membership as a function of cohort-level differences using multinomial logistic regression.</p><p><strong>Results: </strong>Findings provide evidence of variation in EDS-5 score trajectories and in counts of discriminatory situation trajectories across birth cohorts. After adjustments, relative to members of the pre-Brown cohort, members of the Protest cohort are statistically significantly more likely to be members of the trajectory group characterized by high and rapidly declining levels of EDS-5 scores relative to a trajectory characterized by modest and declining EDS-5 scores. We found more evidence for variation in situational trajectory group membership across birth cohorts; however, this variation did not correspond with a clear pattern in terms of younger cohorts consistently experiencing either more or less discriminatory situations than their older counterparts.</p><p><strong>Discussion: </strong>This study underscores the importance of examining perceived discrimination using multiple measurement approaches and efforts to disentangle the role of exposure to historically-varying racialized social systems in contributing to perceptions of unfair treatment at older ages.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zachary G Baker, Andrew Alberth, M Aaron Guest, Allie Peckham, Joahana Segundo, Joseph Saenz
{"title":"Mapping the Trajectories of Social Relations for White, Black, and Hispanic/Latino Individuals Approaching Death with Dementia.","authors":"Zachary G Baker, Andrew Alberth, M Aaron Guest, Allie Peckham, Joahana Segundo, Joseph Saenz","doi":"10.1093/geronb/gbaf062","DOIUrl":"https://doi.org/10.1093/geronb/gbaf062","url":null,"abstract":"<p><strong>Objectives: </strong>Larger social networks are associated with a lower risk of dementia, but little is known about how social networks shift as someone with dementia approaches death. We investigate these shifts while giving special attention to race and ethnicity, which are related to different dementia patterns, social network sizes, and social network makeup.</p><p><strong>Methods: </strong>Participants: 2,301 deceased people with dementia from the Health and Retirement Study (2004-2018; waves=8). Multilevel models estimated associations between dementia, race/ethnicity, time, and close family and friend network size while controlling for several variables, including instrumental activities of daily living, age, proxy status, and disease count, using retrospective and proxy data.</p><p><strong>Results: </strong>Social networks shrank linearly as death approached. A decrease in close friends primarily drove shrinkage. However, when race/ethnicity was crossed with time, Hispanic/Latino persons with dementia showed the opposite pattern. As Hispanic/Latino persons with dementia approached death, the number of close extended family members increased dramatically: one additional person every 4 years.</p><p><strong>Discussion: </strong>Dementia risk, social networks, and patterns of social network shrinking are unequal across people of different races and ethnicities. Adding nuance to known patterns, network shrinkage may be a phenomenon of White persons with dementia. In contrast, patterns of stable or even increasing numbers of network members may better describe Black and Hispanic/Latino networks, respectively. These findings may reveal unique strengths of Black and Hispanic/Latino networks that could be leveraged to develop care and support for individuals with dementia and those they leave behind.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyun-Jun Kim, Karen Fredriksen-Goldsen, Christi Nelson
{"title":"A Longitudinal Analysis of Social Connectedness and Subjective Cognitive Impairment and Racial and Ethnic Differences Among LGBTQ Midlife and Older Adults.","authors":"Hyun-Jun Kim, Karen Fredriksen-Goldsen, Christi Nelson","doi":"10.1093/geronb/gbaf070","DOIUrl":"https://doi.org/10.1093/geronb/gbaf070","url":null,"abstract":"<p><strong>Objectives: </strong>Lesbian, gay, bisexual, transgender, and queer (LGBTQ) midlife and older adults are known to face elevated risks of subjective cognitive impairment (SCI). This study examines the relationships between multifaceted aspects of social connectedness and SCI among LGBTQ midlife and older adults, taking into consideration racial and ethnic differences.</p><p><strong>Methods: </strong>We used biennial longitudinal data from the Aging with Pride: National Health, Aging, and Sexuality/Gender Study of LGBTQ adults aged 50 and older, with repeated measures of SCI from 2014 to 2020. We employed hierarchical linear mixed models to estimate the overall level of and changes in SCI, their associations with social connectedness properties, and racial and ethnic heterogeneity in the associations.</p><p><strong>Results: </strong>The time-only model revealed a significant linear increase in SCI over time, but this time effect disappeared after controlling for background characteristics and social connectedness properties. Results of interaction effects of time and social connectedness revealed that a steeper increase in SCI is observed for those with low network diversity, diminished network size, and reduced LGBTQ community engagement. When compared to non-Hispanic Whites, Hispanics, Blacks, and individuals of other races showed a higher SCI. The interaction effects of time and social connectedness on SCI were pronounced among Hispanics.</p><p><strong>Discussion: </strong>Social isolation is a major concern among LGBTQ midlife and older adults. This study suggests that promoting social connectedness may help alleviate the increase in SCI. Addressing racial and ethnic differences is imperative in developing public health policies and interventions for this underserved and demographically diverse at-risk population.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mengyao Hu, Yi Lu Murphey, Tian Qin, Edmundo R Melipillán, Laura B Zahodne, Richard Gonzalez, Vicki A Freedman
{"title":"Enhancing Dementia Classification for Diverse Demographic Groups: Using Vision Transformer-Based Continuous Scoring of Clock Drawing Tests.","authors":"Mengyao Hu, Yi Lu Murphey, Tian Qin, Edmundo R Melipillán, Laura B Zahodne, Richard Gonzalez, Vicki A Freedman","doi":"10.1093/geronb/gbaf065","DOIUrl":"https://doi.org/10.1093/geronb/gbaf065","url":null,"abstract":"<p><strong>Objective: </strong>Alzheimer's disease and related dementias significantly impact older adults' quality of life. The clock-drawing test (CDT) is a widely used dementia screening tool due to its ease of administration and effectiveness. However, manual CDT-coding in large-scale studies can be time-intensive and prone to coding errors and is typically limited to ordinal responses. In this study, we developed a continuous CDT score using a deep learning neural network (DLNN) and evaluated its ability to classify participants as having dementia or not.</p><p><strong>Methods: </strong>Using a nationally representative sample of older adults from the National Health and Aging Trends Study (NHATS), we trained deep learning models on CDT images to generate both ordinal and continuous scores. Using a modified NHATS dementia classification algorithm as a benchmark, we computed the Area Under the Receiver Operating Characteristic Curve for each scoring approach. Thresholds were determined by balancing sensitivity and specificity, and demographic-specific thresholds were compared to a uniform threshold for classification accuracy.</p><p><strong>Results: </strong>Continuous CDT scores provided more granular thresholds than ordinal scores for dementia classification, which vary by demographic characteristics. Lower thresholds were identified for Black individuals, those with lower education, and those ages 90 or older. Compared to ordinal scores, continuous scores also allowed for a more balanced sensitivity and specificity.</p><p><strong>Discussion: </strong>This study demonstrates the potential of continuous CDT generated by DLNN to enhance dementia classification. By identifying demographic-specific thresholds, it offers a more inclusive and adaptive approach, which could lead to improved guidelines for using CDT in dementia screening.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allison A M Bielak, Jacqueline A Mogle, Martin J Sliwinski
{"title":"Within- and Between-Person Differences in Activity Factor Structure: Results From an Ecological Momentary Assessment Study.","authors":"Allison A M Bielak, Jacqueline A Mogle, Martin J Sliwinski","doi":"10.1093/geronb/gbaf017","DOIUrl":"10.1093/geronb/gbaf017","url":null,"abstract":"<p><strong>Objectives: </strong>Studies using ecological momentary assessment (EMA) of activity participation rely on items tapping domains informed by factor analyses based on single time points. Analyses from a single time point focus on differences between participants and provide little insight into how activities cluster together within a person across moments or days. The present study compared the factor structure in activity participation between- and within-persons using an expanded set of momentary activity items in middle and older adulthood.</p><p><strong>Methods: </strong>Using tablets, 81 adults aged 41 to 94 years reported activities completed in the past 3-4 hr 5 times per day for 14 days.</p><p><strong>Results: </strong>The most common activities during the day involved social interactions, reading, and computer work. Watching TV or videos was the most common evening activity. Multilevel factor analysis simultaneously computed both intra-individual factors (within-person) and inter-individual factors (between-person). Four within-person and 4 between-person factors provided the best model fit, with 3 common factors: cognitive (read, computer); social (events, mentoring, providing care); and passive (TV, games). There were notable differences in the fourth factor.</p><p><strong>Discussion: </strong>Although three common activity factors were found between individuals and within persons from day to day, the divergence between the fourth intra- and inter-individual factors provides insight into how activity engagement operates at different timescales and likely reflects daily demands versus long-term goals. EMA provides a window into engagement throughout and across days, but researchers who commonly use retrospective reports of between-person activity engagement may find distinctly different results from factor analyses.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Stepfamily Structure on Older Parents' Frequency of Contact With and Care Receipt From Adult Biological and Stepchildren in the Netherlands.","authors":"Suzan van der Pas, Theo G van Tilburg","doi":"10.1093/geronb/gbaf015","DOIUrl":"10.1093/geronb/gbaf015","url":null,"abstract":"<p><strong>Objectives: </strong>Older people are increasingly entering their later years in stepfamilies. Because adult children play a central role in older parents' support networks, there is concern that the generally weaker intergenerational ties found in stepfamilies may imply an impending deficit in the care available to stepparents. It is currently unclear whether there are differences across stepfamily types including stepfamilies with only biological children. The aim of the study is to examine whether there are differences in contact frequency with and care receipt from adult biological and stepchildren in biological and different types of stepfamilies.</p><p><strong>Methods: </strong>Data are from the Longitudinal Aging Study Amsterdam (1992-2022; 10 observations); respondents' ages varied between 54 and 101. An average of 3.7 observations are available from 2,761 parents in biological families and 647 parents in stepfamilies.</p><p><strong>Results: </strong>Parents in biological families and in stepfamilies with joint children had more contact than in other stepfamily types. There was less contact in stepfamilies with biological and stepchildren formed in midlife and in families with only stepchildren. There were small differences in care receipt; the lowest likelihood was in composite families.</p><p><strong>Discussion: </strong>Our study challenges the idea that the relationships of the adult child to older parents in all stepfamilies are weaker than in biological families and points to the importance of considering that only some stepfamilies are vulnerable in terms of contact frequency. We query whether stepfamilies are resilient, for example, to greater pressures from a sharp increase in care needs for one or both parents.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11986201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilie T Reas, Humberto Parada, Jaclyn Bergstrom, Linda K McEvoy
{"title":"Modifiable Risk Factors for Cognitive Decline in Community-Dwelling Older Adults Differ by Sex and APOE4.","authors":"Emilie T Reas, Humberto Parada, Jaclyn Bergstrom, Linda K McEvoy","doi":"10.1093/geronb/gbaf005","DOIUrl":"10.1093/geronb/gbaf005","url":null,"abstract":"<p><strong>Objectives: </strong>The extent to which lifestyle shapes trajectories of normal cognitive aging, and the factors with highest potential for mitigating cognitive decline, remain poorly characterized.</p><p><strong>Methods: </strong>Participants of the Rancho Bernardo Study underwent demographic, health, and behavioral characterization at baseline, along with up to 7 cognitive assessments over a 27-year follow-up period. Factor analysis of 24 baseline risk variables identified 9 composite factors. Mixed effects models on data from 1,489 participants (aged 45-95 years at baseline) assessed prediction of cognitive change by baseline factor scores. Models were repeated stratified by sex and APOE4 status.</p><p><strong>Results: </strong>Factors of hyperlipidemia and obesity; marriage and depression; occupation and education; and physical activity and subjective health best predicted rates of decline across multiple cognitive domains. Distinct risk profiles were identified for women and men, and for APOE4 carriers and non-carriers. Models of composite risk estimated that potential savings could amount to 7-9.5 years of preserved cognitive health span for low- versus high-risk profiles. Magnitudes of aggregate risk effects were greater among women across cognitive domains, and for APOE4 carriers for memory and verbal fluency.</p><p><strong>Discussion: </strong>Multifactorial life-course approaches to manage cardiometabolic health and promote physical, cognitive, and social engagement may help to mitigate cognitive decline with age, with composite risk associated with up to a decade of preserved cognitive health span. Differences by sex and APOE4 in risk profiles and their potential for risk reduction, highlight the importance of developing personalized recommendations for multidomain approaches to cognitive health maintenance throughout the life-course.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uyen T M Vu, Sarah Tomaszewski Farias, Ladson Hinton, Van T Park, Quyen Q Tiet, Rachel A Whitmer, Sierra Heuer, Boi-San Nguyen, Oanh L Meyer
{"title":"War Trauma and Strength: A Qualitative Study of Participants in the Vietnamese Insights into Cognitive Aging Program.","authors":"Uyen T M Vu, Sarah Tomaszewski Farias, Ladson Hinton, Van T Park, Quyen Q Tiet, Rachel A Whitmer, Sierra Heuer, Boi-San Nguyen, Oanh L Meyer","doi":"10.1093/geronb/gbaf019","DOIUrl":"10.1093/geronb/gbaf019","url":null,"abstract":"<p><strong>Objectives: </strong>Vietnamese Americans are the fourth largest Asian subgroup in the United States, but little qualitative work has been done on their war and migration experiences. In this study, we delineated the war-related traumas and strength in participants of the Vietnamese Insights into Cognitive Aging Program (VIP).</p><p><strong>Methods: </strong>VIP is a longitudinal study of 548 Vietnamese Americans aged 65+ years living in Northern California. During Visit 1, a semi-structured interview was conducted on participants' life and experiences in Vietnam and immigration to the United States. Using data at one of the recruitment sites, interviews of participants having the highest total self-reported traumas were transcribed in Vietnamese (n = 43) for coding and analysis following a thematic approach.</p><p><strong>Results: </strong>Participants were 73.2 years old on average (SD = 5.48). Most were male (67.4%) and had attempted to escape Vietnam by boat at least once (67%). Two major themes were found: (1) experiences of adversity and suffering, which included subthemes on tough life experiences during the war, imprisonment and hard life after the war, escaping by boat and living in the refugee camps, witnessing or hearing about others' traumas during the war and escape, and experiences of loss, and (2) personal fortitude and gratitude, which included subthemes on fortitude and endurance, personal skills to cope and navigate, and perceived \"luck and blessings.\"</p><p><strong>Discussion: </strong>Results from this study revealed various traumas and aspects of strength. These findings can contribute to future VIP research on cognitive aging and inform research and practice on health disparities.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults.","authors":"Joseph Saenz, Nekehia T Quashie, Xing Zhang","doi":"10.1093/geronb/gbaf010","DOIUrl":"10.1093/geronb/gbaf010","url":null,"abstract":"<p><strong>Objectives: </strong>A growing body of research has identified associations between family size and cognition in older adults. These studies largely focus on older adults' own fertility history instead of sibship size, defined as one's number of siblings. Sibship size may affect cognitive development during early childhood, creating differences that may persist into late life. Using a gendered life course framework, this study evaluates how family size across the life course (both sibship size and number of children) relates to cognitive aging among older Mexican adults.</p><p><strong>Methods: </strong>Data come from the 2012, 2015, 2018, and 2021 waves of the Mexican Health and Aging Study (n = 14,872 adults age 50+). We use latent growth curve models to evaluate how family size (sibship size and fertility history) relates with levels of latent general cognitive ability and 9-year cognitive decline and variation across gender.</p><p><strong>Results: </strong>Small sibship size related to higher levels of cognitive ability among men, but not women. This benefit was somewhat reduced when educational attainment was accounted for. Regarding fertility history, we observed an inverse U-shaped relationship with the level of cognitive ability, regardless of gender, that remained significant even after accounting for sibship size and other confounders. Neither family size measure predicted the rate of cognitive decline.</p><p><strong>Discussion: </strong>This research broadens our understanding of family size and cognition associations in the context of Mexico's changing demographics that challenge the reliance on family support in late life and highlights potential gender differences.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}