Journals of Gerontology Series B-Psychological Sciences and Social Sciences最新文献

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'Kinlessness', social connectedness, and subjective well-being in Europe.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-21 DOI: 10.1093/geronb/gbaf055
Marco Tosi, Thijs Van den Broek
{"title":"'Kinlessness', social connectedness, and subjective well-being in Europe.","authors":"Marco Tosi, Thijs Van den Broek","doi":"10.1093/geronb/gbaf055","DOIUrl":"https://doi.org/10.1093/geronb/gbaf055","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines the association between family structure and subjective well-being by focusing on the moderating effects of social connectedness across genders and country contexts. We compare the well-being of older adults across four family types: those with both a partner and children, those with a partner but not children, those with children but no partner, and those without a partner and children ('kinless').</p><p><strong>Methods: </strong>We use data from six waves of the European Social Survey (2012-2024) and estimate ordered logistic regression models of happiness and life satisfaction among middle-aged and older Europeans aged 50-104 (62,687 men and 73,323 women). We include interactions in the analysis to test whether social connectedness mitigates the well-being differences between kinless adults and partnered parents.</p><p><strong>Results: </strong>The results show that middle-aged and older adults, especially men, without a partner exhibit lower levels of happiness and life satisfaction compared to their partnered counterparts, regardless of the absence of children. The subjective well-being gap between partnered and unpartnered men diminishes according to their level of social connectedness, a moderating effect primarily observed in Nordic and Western European countries.</p><p><strong>Discussion: </strong>Contrary to the notion that 'kinlessness' leads to ageing alone, middle-aged and older men in less family-centered countries are able to alleviate the detrimental impact of partnerlessness on subjective well-being through increased social connectedness. In contrast, in countries where family ties are more emphasized, particularly in Eastern Europe, un-partnered adults face greater well-being challenges that are harder to offset with social connectedness.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of attentional focus on gait stability and conscious movement processing during challenging walking conditions in older adults.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-21 DOI: 10.1093/geronb/gbaf059
Toby C T Mak, Shamay S M Ng, Debbie C L Chan, Thomson W L Wong
{"title":"The influence of attentional focus on gait stability and conscious movement processing during challenging walking conditions in older adults.","authors":"Toby C T Mak, Shamay S M Ng, Debbie C L Chan, Thomson W L Wong","doi":"10.1093/geronb/gbaf059","DOIUrl":"https://doi.org/10.1093/geronb/gbaf059","url":null,"abstract":"<p><strong>Objectives: </strong>It has been proposed that the effect of an external focus in gait might be more beneficial in more challenging tasks compared to a natural walking condition. This study sought to a) address any causal link between an external focus and improved gait stability during walking on an unstable surface and b) explore any possible psycho-cognitive mechanism underpinning these changes in older adults.</p><p><strong>Methods: </strong>Ninety-eight older adults (mean age: 70.6±4.6) were invited to walk along an 8-meter elevated, foam walkway at a self-selected pace under three blocks of attentional focus conditions (i.e., internal focus, external focus, and control) for a total of nine trials (three trials for each condition). Gait stability was represented by the variability of spatial and temporal gait parameters. Electroencephalography (EEG) T3-Fz coherence was used to indicate real-time conscious movement processing during walking.</p><p><strong>Results: </strong>Older adults displayed significantly lower variability of stride length and step width under an external focus condition compared to control. No gait changes were observed between an internal focus condition and control. There were no significant differences in EEG T3-Fz coherence among the three conditions.</p><p><strong>Discussion: </strong>We demonstrate evidence of a causal link between an external focus and improved gait stability in older adults under a challenging walking environment. However, we postulate that this improvement might be independent of real-time conscious movement processing. Our findings nonetheless suggest that external focus strategies might be an effective rehabilitative approach for falls prevention by reducing gait variability during adaptive locomotion in older adults.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socially Withdrawn or Socially Engaged? The Impacts of Caring for Grandchildren on Social Participation among Older Adults in China.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-14 DOI: 10.1093/geronb/gbaf054
Jason Wong, Mengke Zhao, Yuying Tong, Feinian Chen
{"title":"Socially Withdrawn or Socially Engaged? The Impacts of Caring for Grandchildren on Social Participation among Older Adults in China.","authors":"Jason Wong, Mengke Zhao, Yuying Tong, Feinian Chen","doi":"10.1093/geronb/gbaf054","DOIUrl":"https://doi.org/10.1093/geronb/gbaf054","url":null,"abstract":"<p><strong>Objectives: </strong>Grandparents caring for grandchildren (i.e., grandparenting) is a key aspect of intergenerational family dynamics. While extensive research has documented the health implications of grandparenting, relatively few studies have explored its association with social well-being. Grandparenting can either promote or constrain grandparents' social participation, depending on caregiving intensity and intergenerational living arrangements. These associations may also vary by gender due to gendered social norms and differences in opportunities for social networking. This study investigates the longitudinal association between grandparenting and social participation among grandparents and examines how this association differs by gender.</p><p><strong>Methods: </strong>Data are drawn from the 2011, 2013, and 2018 waves of the China Health and Retirement Longitudinal Study (N = 8,907, aged 45-80). We use fixed-effects Poisson regression models to examine the association between different types of grandparenting and the number of social participation activities of grandparents. Subgroup analyses are conducted by grandparents' gender.</p><p><strong>Results: </strong>In fixed-effects regression models adjusting for time-varying covariates, we find that nonintensive noncoresident grandparenting, intensive noncoresident grandparenting, and skipped-generation grandparenting are associated with increased social participation among grandparents compared to no grandparenting. However, no significant difference in social participation is observed between three-generation grandparenting and no grandparenting groups. Grandfathers show higher levels of social participation when engaging in nonintensive or intensive noncoresident grandparenting, whereas grandmothers experience increased social participation primarily with nonintensive noncoresident grandparenting.</p><p><strong>Discussion: </strong>Overall, grandparenting promotes rather than hinders social participation among grandparents. This study highlights the role of intergenerational family relationships in facilitating older adults' social engagement in later life.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the Stress Process Among Mexican American Adults aged 50 and older in the United States.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-13 DOI: 10.1093/geronb/gbaf051
Elizabeth Muñoz, Jean Choi, Harshini Thanga Raj Malini, Asma Maredia, Lourdes S Romañach Álvarez
{"title":"Understanding the Stress Process Among Mexican American Adults aged 50 and older in the United States.","authors":"Elizabeth Muñoz, Jean Choi, Harshini Thanga Raj Malini, Asma Maredia, Lourdes S Romañach Álvarez","doi":"10.1093/geronb/gbaf051","DOIUrl":"https://doi.org/10.1093/geronb/gbaf051","url":null,"abstract":"<p><strong>Objectives: </strong>Compared to non-Latino White adults, Mexican Americans in the U.S. are disproportionally exposed to more social, environmental, and economic stress that increase risk for poor physical and mental health outcomes. Despite this, Mexican Americans tend to benefit from a mortality and mental health advantage indicative of unique resilience and risk factors. We assessed stress exposure and appraisals in eight domains among Mexican Americans compared to non-Latino Whites, and evaluated if compared to high acculturation, low acculturation may be associated with lower stress exposure and appraisal in Mexican Americans.</p><p><strong>Methods: </strong>We used data from 2,004 participants (49.4% Mexican American; 50.6% non-Latino White; age range = 50 - 92). Stress exposure was the total of endorsed events and stress appraisal was the average reported severity. Poisson and linear regression models tested race/ethnic (and acculturation) differences in exposure and appraisal.</p><p><strong>Results: </strong>There were no differences in the total number of stress exposures between Mexican American and non-Latino White adults (IRR = 1.08 [95% CI: 0.99 - 1.18]), but the types of stress exposures differed. Compared to Mexican Americans, non-Latino Whites consistently endorsed higher stress appraisal (B = 0.23 [SE = .04], p <.0001). Mexican Americans with low acculturation reported lower stress appraisal compared to Mexican Americans with high acculturation (B = -0.45 [SE = 0.05], p <.0001).</p><p><strong>Discussion: </strong>Results indicate that the stress process among Mexican American adults may differ from traditional propositions and highlight the need for more research on the intricacies of the stress process for Mexican Americans in the U.S.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental health trajectories of men and women who start providing personal care: European findings from SHARE using propensity score matching.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-13 DOI: 10.1093/geronb/gbaf053
Morten Wahrendorf, Anne McMunn, Baowen Xue, Valerie Schaps, Christian Deindl, Giorgio Di Gessa, Rebecca E Lacey
{"title":"Mental health trajectories of men and women who start providing personal care: European findings from SHARE using propensity score matching.","authors":"Morten Wahrendorf, Anne McMunn, Baowen Xue, Valerie Schaps, Christian Deindl, Giorgio Di Gessa, Rebecca E Lacey","doi":"10.1093/geronb/gbaf053","DOIUrl":"https://doi.org/10.1093/geronb/gbaf053","url":null,"abstract":"<p><strong>Objectives: </strong>We examine the mental health trajectories of people who start providing personal care and compare their trajectories with matched controls who remain non-carers. We also investigate whether trajectories vary by gender, financial resources, and supportive long-term care policies.</p><p><strong>Methods: </strong>Using nine waves of the Survey of Health, Ageing and Retirement in Europe, collected in 28 European countries from 2004 to 2022, we analyse longitudinal data from 68,075 men and women aged 50 or older. We identify transitions into regular personal care within the household and use depressive symptoms from up to four waves before and after transitioning into care to measure mental health trajectories. Financial resources are measured by household wealth, while three macro indicators assess (1) support for caregivers, (2) support for care recipients, and (3) public care service availability. Propensity score matching, applied separately for men and women, identifies matched non-caregivers from the same country, and we use piecewise growth curve models to examine changes before, during, and after becoming a carer.</p><p><strong>Results: </strong>Both men and women have a clear increase in depressive symptoms when becoming a regular carer, and this increase even begins before the transition. The increase during the transition is slightly more pronounced for women and those with lower wealth, but we find no systematic differences by policy indicators.</p><p><strong>Discussion: </strong>Our study highlights the need for improved support for carers. While national policies may influence the likelihood of becoming a carer, their effectiveness in mitigating the mental health impact of caring remains unclear.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Key Predictors of Generativity in Adulthood: A Machine Learning Analysis. 成年期生育能力的关键预测因素:机器学习分析。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbae204
Mohsen Joshanloo
{"title":"Key Predictors of Generativity in Adulthood: A Machine Learning Analysis.","authors":"Mohsen Joshanloo","doi":"10.1093/geronb/gbae204","DOIUrl":"10.1093/geronb/gbae204","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to explore a broad range of predictors of generativity in older adults. The study included over 60 predictors across multiple domains, including personality, daily functioning, socioeconomic factors, health status, and mental well-being.</p><p><strong>Methods: </strong>A random forest machine learning algorithm was used. Data were drawn from the Midlife in the United States (MIDUS) survey.</p><p><strong>Results: </strong>Social potency, openness, social integration, personal growth, and achievement orientation were the strongest predictors of generativity. Notably, many demographic (e.g., income) and health-related variables (e.g., chronic health conditions) were found to be much less predictive.</p><p><strong>Discussion: </strong>This study provides new data-driven insights into the nature of generativity. The findings suggest that generativity is more closely associated with eudaimonic and plasticity-related variables (e.g., personal growth and social potency) rather than hedonic and homeostasis-oriented ones (e.g., life satisfaction and emotional stability). This indicates that generativity is an inherently dynamic construct, driven by a desire for exploration, social contribution, and personal growth.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resilience Factors Affecting Long-Term Trajectories of Depressive Symptoms in the Aftermath of the Great East Japan Earthquake and Tsunami Among Older Adults. 影响东日本大地震和海啸后老年人抑郁症状长期轨迹的复原力因素。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbae182
Aki Yazawa, Xiaoyu Li, Koichiro Shiba, Sakurako S Okuzono, Hiroyuki Hikichi, Jun Aida, Katsunori Kondo, Ichiro Kawachi
{"title":"Resilience Factors Affecting Long-Term Trajectories of Depressive Symptoms in the Aftermath of the Great East Japan Earthquake and Tsunami Among Older Adults.","authors":"Aki Yazawa, Xiaoyu Li, Koichiro Shiba, Sakurako S Okuzono, Hiroyuki Hikichi, Jun Aida, Katsunori Kondo, Ichiro Kawachi","doi":"10.1093/geronb/gbae182","DOIUrl":"10.1093/geronb/gbae182","url":null,"abstract":"<p><strong>Objectives: </strong>We examined long-term trajectories of depressive symptoms among older adults following exposure to the 2011 Great East Japan Earthquake and Tsunami. We further characterized the pre- and post-disaster social relationship factors that predicted membership in each trajectory group.</p><p><strong>Methods: </strong>Data from 4 time points (including pre-disaster data) were used to analyze the depression trajectories of 2,033 survivors through a group-based trajectory model. Multinomial logistic analysis was used to investigate the social relationship factors (i.e., social interactions with neighbors, social support, social participation, and social cohesion) that predicted membership to each trajectory group.</p><p><strong>Results: </strong>Five distinct trajectories of depressive symptoms were identified; stably not depressed (12.4%), increased after the disaster (14.2%), decreased after the disaster (8.8%), persistent mild depressive symptoms (28.1%), and persistent severe depressive symptoms (36.5%). Compared to those who were stably not depressed, those who experienced an increase in symptoms were more likely to experience housing damage and not to participate in social activities. Compared to those who were stably mildly depressed, those who experienced a decrease in symptoms had higher pre-disaster social interactions with neighbors as well as higher post-disaster social support. Adults with persistent severe symptoms were physically, psychologically, and socially vulnerable preceding the disaster.</p><p><strong>Discussion: </strong>The study revealed the heterogeneity of older adults experiencing depressive symptoms in the wake of major disaster. Those who experienced increased symptoms after the disaster showed a chronic rather than temporary rise, while those with pre-disaster depressive symptoms showed sustained symptoms regardless of disaster-related trauma.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Employment Responses to a Partner's Disability Onset ("Care Shocks"): Do Working Conditions Matter? 雇主对伴侣残疾的反应(护理冲击):工作条件重要吗?
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbae208
Constance Beaufils, Ben Baumberg Geiger, Karen Glaser
{"title":"Employment Responses to a Partner's Disability Onset (\"Care Shocks\"): Do Working Conditions Matter?","authors":"Constance Beaufils, Ben Baumberg Geiger, Karen Glaser","doi":"10.1093/geronb/gbae208","DOIUrl":"10.1093/geronb/gbae208","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines employment responses to a partner's disability onset and how this is moderated by working conditions: job satisfaction and psychosocial job demands.</p><p><strong>Methods: </strong>We use longitudinal nationally representative data from the English Longitudinal Study of Aging. Following the health shock literature, we identify individuals whose partners report the onset of difficulties in activities of daily living (ADL) or instrumental activities of daily living (IADL) between 2 waves (n = 1,020) as experiencing a \"care shock.\" We combine coarsened exact matching and entropy balancing, and logistic modeling to estimate the impact of such a \"care shock\" on the probability of leaving paid work, working part-time, changing jobs, or looking for a new job. We also explore the moderating effect of gender and working conditions (i.e., job demands and job satisfaction) on the impact of a \"care shock\" on work transitions.</p><p><strong>Results: </strong>Our findings show that \"care shocks\" significantly increase individuals' likelihood of leaving paid work. This effect is moderated by job demands and job satisfaction. Individuals who report high job demands and job dissatisfaction before the care shock are significantly more likely to leave paid work. In contrast, those with low job demands or job satisfaction show no significant difference in their likelihood of leaving paid work.</p><p><strong>Discussion: </strong>Our study highlights the role of working conditions in moderating the impact of care shocks on paid work. It informs workplace policies, as our results suggest that adapting working conditions may facilitate participation in the labor market in late career stages.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts. 阿尔茨海默病、轴突损伤和星形胶质增生的孤独和生物标志物:两个纵向队列的协调分析。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbaf006
Antonio Terracciano, Keenan A Walker, Yang An, Murat Bilgel, Angelina R Sutin, Martina Luchetti, Selin Karakose, Yannick Stephan, Kaj Blennow, Henrik Zetterberg, Nicholas J Ashton, Thomas K Karikari, Przemysław R Kac, Abhay R Moghekar, Madhav Thambisetty, Luigi Ferrucci, Susan M Resnick
{"title":"Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts.","authors":"Antonio Terracciano, Keenan A Walker, Yang An, Murat Bilgel, Angelina R Sutin, Martina Luchetti, Selin Karakose, Yannick Stephan, Kaj Blennow, Henrik Zetterberg, Nicholas J Ashton, Thomas K Karikari, Przemysław R Kac, Abhay R Moghekar, Madhav Thambisetty, Luigi Ferrucci, Susan M Resnick","doi":"10.1093/geronb/gbaf006","DOIUrl":"10.1093/geronb/gbaf006","url":null,"abstract":"<p><strong>Objectives: </strong>Loneliness is associated with an elevated risk of dementia. There is mixed evidence from imaging studies on whether loneliness is associated with neuropathology in dementia-free adults. This study tests whether loneliness is associated with plasma neurobiomarkers of amyloid (Aβ42/Aβ40), phosphorylated tau 181 (pTau181), neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP) and imaging measures of amyloid and tau.</p><p><strong>Methods: </strong>Participants were cognitively unimpaired older adults from the Baltimore Longitudinal Study on Aging (BLSA; N = 1,028 individuals and up to 2,277 neurobiomarker measurements; Baseline mean age = 66, SD = 15 years) and the UK Biobank (N = 1,263 individuals and up to 2,526 neurobiomarker measurements; Baseline mean age = 60, SD = 7 years). Single-item measures of loneliness and the Quanterix Single Molecule Array assays were used in both samples. In a subset of BLSA participants, positron emission tomography (PET) was used to assess cerebral amyloid burden (n = 220) and tau in the entorhinal cortex (n = 102).</p><p><strong>Results: </strong>In both samples and meta-analyses, loneliness was unrelated to plasma measures of Aβ42/Aβ40, pTau181, NfL, and GFAP. Changes in loneliness were also unrelated to changes in the plasma neurobiomarkers, and no consistent evidence of moderation by age, sex, or APOE ε4 allele was found. Loneliness was also unrelated to PET-based measures of amyloid and tau.</p><p><strong>Discussion: </strong>This study found no associations between loneliness and measures of Alzheimer's disease pathology, axonal damage, or astrogliosis.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mindfulness Interventions in Older Adults for Mental Health and Well-Being: A Meta-Analysis. 正念干预对老年人心理健康和幸福的影响:一项荟萃分析。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbae205
Paul Verhaeghen, Shelley N Aikman, Grazia Mirabito
{"title":"Mindfulness Interventions in Older Adults for Mental Health and Well-Being: A Meta-Analysis.","authors":"Paul Verhaeghen, Shelley N Aikman, Grazia Mirabito","doi":"10.1093/geronb/gbae205","DOIUrl":"10.1093/geronb/gbae205","url":null,"abstract":"<p><strong>Objectives: </strong>Mindfulness interventions are consistently associated with beneficial effects in younger adults. In this meta-analysis, we seek to quantify the effectiveness of mindfulness interventions for the mental health and well-being of older adults.</p><p><strong>Methods: </strong>We include 46 studies that implemented a mindfulness intervention (MBSR = 20; MBCT = 9; ad hoc protocol = 17) with older adults (samples with an average age of 60 or older; healthy adults = 20; adults with underlying symptoms = 26), examining a wide range of outcome measures (e.g., stress, quality of life, sleep).</p><p><strong>Results: </strong>Mindfulness interventions in older adults yielded an estimated Hedges' g of 0.25. Moderator analyses revealed three significant effects. Type of intervention mattered, with the effect size for MBSR not significantly different from zero (Hedges' g = 0.12) while the effect sizes for MBCT (Hedges' g = 0.33) and \"other\" interventions (Hedges' g = 0.36) were. Outcome measure mattered, with significant beneficial effect sizes for mental functioning (Hedges' g = 0.59), depression (Hedges' g = 0.35), sleep (Hedges' g = 0.39), anxiety (Hedges' g = 0.32), \"other\" (Hedges' g = 0.24), stress (Hedges' g = 0.22) and mindfulness (Hedges' g = 0.23). Finally, whether the outcome was targeted (e.g., measures of depression in a population suffering from major depressive disorder) mattered: variables that measured targeted outcomes yielded stronger effects (Hedges' g = 0.30).</p><p><strong>Discussion: </strong>Mindfulness interventions with older adults are effective, but modestly so. The extant literature is limited by reliance on modified interventions that have not been evaluated for effectiveness.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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