Journals of Gerontology Series B-Psychological Sciences and Social Sciences最新文献

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Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts. 阿尔茨海默病、轴突损伤和星形胶质增生的孤独和生物标志物:两个纵向队列的协调分析。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbaf006
Antonio Terracciano, Keenan A Walker, Yang An, Murat Bilgel, Angelina R Sutin, Martina Luchetti, Selin Karakose, Yannick Stephan, Kaj Blennow, Henrik Zetterberg, Nicholas J Ashton, Thomas K Karikari, Przemysław R Kac, Abhay R Moghekar, Madhav Thambisetty, Luigi Ferrucci, Susan M Resnick
{"title":"Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts.","authors":"Antonio Terracciano, Keenan A Walker, Yang An, Murat Bilgel, Angelina R Sutin, Martina Luchetti, Selin Karakose, Yannick Stephan, Kaj Blennow, Henrik Zetterberg, Nicholas J Ashton, Thomas K Karikari, Przemysław R Kac, Abhay R Moghekar, Madhav Thambisetty, Luigi Ferrucci, Susan M Resnick","doi":"10.1093/geronb/gbaf006","DOIUrl":"10.1093/geronb/gbaf006","url":null,"abstract":"<p><strong>Objectives: </strong>Loneliness is associated with an elevated risk of dementia. There is mixed evidence from imaging studies on whether loneliness is associated with neuropathology in dementia-free adults. This study tests whether loneliness is associated with plasma neurobiomarkers of amyloid (Aβ42/Aβ40), phosphorylated tau 181 (pTau181), neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP) and imaging measures of amyloid and tau.</p><p><strong>Methods: </strong>Participants were cognitively unimpaired older adults from the Baltimore Longitudinal Study on Aging (BLSA; N = 1,028 individuals and up to 2,277 neurobiomarker measurements; Baseline mean age = 66, SD = 15 years) and the UK Biobank (N = 1,263 individuals and up to 2,526 neurobiomarker measurements; Baseline mean age = 60, SD = 7 years). Single-item measures of loneliness and the Quanterix Single Molecule Array assays were used in both samples. In a subset of BLSA participants, positron emission tomography (PET) was used to assess cerebral amyloid burden (n = 220) and tau in the entorhinal cortex (n = 102).</p><p><strong>Results: </strong>In both samples and meta-analyses, loneliness was unrelated to plasma measures of Aβ42/Aβ40, pTau181, NfL, and GFAP. Changes in loneliness were also unrelated to changes in the plasma neurobiomarkers, and no consistent evidence of moderation by age, sex, or APOE ε4 allele was found. Loneliness was also unrelated to PET-based measures of amyloid and tau.</p><p><strong>Discussion: </strong>This study found no associations between loneliness and measures of Alzheimer's disease pathology, axonal damage, or astrogliosis.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mindfulness Interventions in Older Adults for Mental Health and Well-Being: A Meta-Analysis. 正念干预对老年人心理健康和幸福的影响:一项荟萃分析。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-12 DOI: 10.1093/geronb/gbae205
Paul Verhaeghen, Shelley N Aikman, Grazia Mirabito
{"title":"Mindfulness Interventions in Older Adults for Mental Health and Well-Being: A Meta-Analysis.","authors":"Paul Verhaeghen, Shelley N Aikman, Grazia Mirabito","doi":"10.1093/geronb/gbae205","DOIUrl":"10.1093/geronb/gbae205","url":null,"abstract":"<p><strong>Objectives: </strong>Mindfulness interventions are consistently associated with beneficial effects in younger adults. In this meta-analysis, we seek to quantify the effectiveness of mindfulness interventions for the mental health and well-being of older adults.</p><p><strong>Methods: </strong>We include 46 studies that implemented a mindfulness intervention (MBSR = 20; MBCT = 9; ad hoc protocol = 17) with older adults (samples with an average age of 60 or older; healthy adults = 20; adults with underlying symptoms = 26), examining a wide range of outcome measures (e.g., stress, quality of life, sleep).</p><p><strong>Results: </strong>Mindfulness interventions in older adults yielded an estimated Hedges' g of 0.25. Moderator analyses revealed three significant effects. Type of intervention mattered, with the effect size for MBSR not significantly different from zero (Hedges' g = 0.12) while the effect sizes for MBCT (Hedges' g = 0.33) and \"other\" interventions (Hedges' g = 0.36) were. Outcome measure mattered, with significant beneficial effect sizes for mental functioning (Hedges' g = 0.59), depression (Hedges' g = 0.35), sleep (Hedges' g = 0.39), anxiety (Hedges' g = 0.32), \"other\" (Hedges' g = 0.24), stress (Hedges' g = 0.22) and mindfulness (Hedges' g = 0.23). Finally, whether the outcome was targeted (e.g., measures of depression in a population suffering from major depressive disorder) mattered: variables that measured targeted outcomes yielded stronger effects (Hedges' g = 0.30).</p><p><strong>Discussion: </strong>Mindfulness interventions with older adults are effective, but modestly so. The extant literature is limited by reliance on modified interventions that have not been evaluated for effectiveness.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinship Structures for Left Behind Older Adults in High Outmigration Contexts: Evidence from Puerto Rico.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-11 DOI: 10.1093/geronb/gbaf052
Amílcar Matos-Moreno, Diego Alburez-Gutierrez, Iván Williams, Ashton M Verdery, Mariana Fernández Soto, Alexis Santos-Lozada
{"title":"Kinship Structures for Left Behind Older Adults in High Outmigration Contexts: Evidence from Puerto Rico.","authors":"Amílcar Matos-Moreno, Diego Alburez-Gutierrez, Iván Williams, Ashton M Verdery, Mariana Fernández Soto, Alexis Santos-Lozada","doi":"10.1093/geronb/gbaf052","DOIUrl":"10.1093/geronb/gbaf052","url":null,"abstract":"<p><strong>Objectives: </strong>Migration accelerates population aging in high-outmigration contexts. Older adults who remain in high-outmigration contexts are at higher risk of reduced support networks and increased caregiving burden, but prior work has not quantified how migration influences older adults' kinship structures in such places. This study aims to estimate the kinship structures of older adults living in Puerto Rico and the presence of migrant kin.</p><p><strong>Methods: </strong>Data come from the United Nations World Population Prospects from 1950 to 2021. We created a two-sex, multistate, time-variant kinship model to estimate how many and what type of family relationships we can expect for older adults in Puerto Rico and the presence of transnational kin.</p><p><strong>Results: </strong>Our models suggest that a 65+ year-old living in Puerto Rico will have, on average, 5.6 close biological family members in 2021: 2.8 adult children and 2.7 siblings. These numbers represent a decline since 2000, when 65+ year-olds had 6.7 such kin. Under 2021 demographic conditions, adults 65 years of age are expected to have 69% of their total female close kin and 71% of daughters residing in the United States. The expected number of transnational living kin is greater for 2021 compared to 2000.</p><p><strong>Discussion: </strong>Models suggest that future generations of older adults in Puerto Rico will have an increased presence of transnational family members. Thus, public health strategies must adapt to address the needs of transnational families in future generations of older adults.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconceptualizing Neighborhood and Community Third Places: Older Adults' Views through Virtual Photovoice.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-07 DOI: 10.1093/geronb/gbaf049
Joyce Weil, Gitanjali Iyer
{"title":"Reconceptualizing Neighborhood and Community Third Places: Older Adults' Views through Virtual Photovoice.","authors":"Joyce Weil, Gitanjali Iyer","doi":"10.1093/geronb/gbaf049","DOIUrl":"https://doi.org/10.1093/geronb/gbaf049","url":null,"abstract":"<p><strong>Objectives: </strong>Neighborhoods and communities can offer third places, places outside of older adults' individual homes or workplaces, that are meaningful to them. While literature may describe these places, seeing them as photos from the viewpoint of older adults is often absent. The goal is to understand the role and function of neighborhood and community sites as third places in the older adults' lives, as portrayed through their own words and images.</p><p><strong>Methods: </strong>A phenomenographic approach was used with older adults to analyze photovoice-based and narrative data from a virtual photovoice study about the meaning of home for 14 older adults, from October 2022-May 2023, in Baltimore, Maryland. As part of this study, after IRB consent and photovoice protocol review, older adults took up to 10 photos on their smartphones. Each participant then interpreted and shared the meaning of home, neighborhood and community shown in the photos-thus constructing their personal meaning of third place.</p><p><strong>Results: </strong>Four main sets of places that older adults discuss and conceptualize as third places through conversations about their photos. The concept of third places was expressed both traditionally and in novel ways through discussions and images around: a) A community of walkable neighborhood stores and restaurants; b) Age-based community-based activity spaces; c) Larger neighborhood community: Spiritual community and faith-based spaces, and d) Parks and nature.</p><p><strong>Discussion: </strong>These photo-interpreted third places offer additional ways to create a sense of familiarity, social connectedness, and wellbeing while experiencing one's social world in built and natural environments.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual orientation and internalized homophobia of middle aged and older gay and lesbian adults: The role of social relationships.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-07 DOI: 10.1093/geronb/gbaf048
Ella Cohn-Schwartz, Sigal Gooldin, Lian Meiry, Yaacov G Bachner
{"title":"Sexual orientation and internalized homophobia of middle aged and older gay and lesbian adults: The role of social relationships.","authors":"Ella Cohn-Schwartz, Sigal Gooldin, Lian Meiry, Yaacov G Bachner","doi":"10.1093/geronb/gbaf048","DOIUrl":"https://doi.org/10.1093/geronb/gbaf048","url":null,"abstract":"<p><strong>Objectives: </strong>Research is needed about the role of families in relation to issues faced by middle-aged and older gay and lesbian adults, such as internalized homophobia and families of choice. This study examines how families of choice and families of origin shape experiences of internalized homophobia in midlife and older gay and lesbian adults, a population uniquely affected by the cumulative effects of societal stigma over the life course.</p><p><strong>Methods: </strong>We sampled 409 adults aged 50+ (range: 50-85) who self-identify as lesbian women or gay men. They answered a questionnaire about families of choice, families of origin, and internalized homophobia. Mediation models examined the role of families in the association of gender and internalized homophobia.</p><p><strong>Results: </strong>Lesbian women reported lower internalized homophobia compared to gay men, and this was partially explained by their greater likelihood of citing spouses/partners and children as close others. Friends in one's family of choice were not associated with gender or internalized homophobia. Men were more likely to cite close siblings, and this was related to lower internalized homophobia, although siblings did not mediate the association of gender and internalized homophobia.</p><p><strong>Discussion: </strong>Higher internalized homophobia of gay men in later life might be partially explained by being less likely to have a spouse/partner and children, reflecting cumulative effects of lifelong discrimination and stigma. These findings could foster better interventions aimed at specific needs of aging men and women from sexual minorities, considering their life course experiences and social resources.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The differential impact of retirement on contact frequency with family, friends, neighbors, and co-workers.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-06 DOI: 10.1093/geronb/gbaf042
Jasper Bosma, Kène Henkens, Hanna van Solinge
{"title":"The differential impact of retirement on contact frequency with family, friends, neighbors, and co-workers.","authors":"Jasper Bosma, Kène Henkens, Hanna van Solinge","doi":"10.1093/geronb/gbaf042","DOIUrl":"https://doi.org/10.1093/geronb/gbaf042","url":null,"abstract":"<p><strong>Objectives: </strong>Most studies on retirement and social network dynamics focus on the closer social network, leaving the role of more peripheral contacts largely overlooked. This paper studies how retirement affects contact frequency with a wider range of social ties. We formulate and test differential hypotheses for each category of ties, and additionally examine gender and partner status differences.</p><p><strong>Methods: </strong>We analyze three waves of panel data of the NIDI Pension Panel Study (NPPS), collected in the Netherlands between 2015 and 2023 (n=5,238). We use two-way fixed-effects regression models to study within-person change in contact frequency with the different categories of social ties after retirement. To test the differential hypotheses, we conduct Wald tests comparing coefficients across models.</p><p><strong>Results: </strong>The results indicate that retirement stimulates contact primarily with neighbors and friends, to a lesser extent with siblings and (grand)children, and does not affect contact frequency with parents. Contact with ex-co-workers initially increases but then decreases over time. For women, the positive association between retirement and contact with ex-co-workers, friends and children is stronger. Not having a partner reduces the association between retirement and contact with friends and ex-co-workers.</p><p><strong>Discussion: </strong>Our findings suggest that retirees attempt to replace lost workplace interactions by engaging with their former colleagues outside of work and increasing contact with neighbors. Simultaneously, the results suggest substantial continuity in contact with all ties. We suggest that larger changes might take place outside of the ties studied here, with new contacts, and provide several suggestions for future research.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Education, Occupational Environment, and Cognitive Function in Later Life.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-01 DOI: 10.1093/geronb/gbaf043
Qiuchang Katy Cao, Dawn Carr, Miles G Taylor
{"title":"Education, Occupational Environment, and Cognitive Function in Later Life.","authors":"Qiuchang Katy Cao, Dawn Carr, Miles G Taylor","doi":"10.1093/geronb/gbaf043","DOIUrl":"https://doi.org/10.1093/geronb/gbaf043","url":null,"abstract":"<p><strong>Objectives: </strong>Education is among the most robust predictors of cognitive health outcomes in later life. However, few studies have comprehensively evaluated whether and how much of this effect is explained by occupational exposures. This study aims to determine if and how much pre-retirement occupational exposures (occurring before age 60) mediate the association between education and cognitive function at age 65+.</p><p><strong>Methods: </strong>We use data drawn from the Health and Retirement Study (HRS) and Occupation Information Network (O*NET) data. Informed by previous research and theory, we conducted Confirmatory Factor Analyses of occupation-level exposure measures using a longitudinal HRS-O*NET linked dataset we created, and we identified two latent factors: occupational hazards and occupational complexity. Among initially employed adults (age 51-60 at baseline), we used Structural Equation Modeling (SEM) to evaluate the association between education and cognitive function at age 65+, and the role of our two occupational factors in mediating this association.</p><p><strong>Results: </strong>The measurement and structural models both had good model fit (TLI, CFI >= .95, SRMR < .08). We found (a) that education remained a critical predictor of cognitive outcomes in later life even when accounting for occupational exposures, and (b) only hazardous exposures mediated the association between education and cognitive function in later life (a2b2=0.02, p = 0.01), explaining about 17% of the effect of education.</p><p><strong>Discussion: </strong>These findings suggest interventions designed to decrease exposure to hazardous occupational exposures could reduce some of the cognitive disadvantages in later life associated with lower levels of education.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Audiovisual integration facilitates age-related perceptual decision-making.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-03-01 DOI: 10.1093/geronb/gbaf037
Xiangfu Yang, Weiping Yang, Ruizhi Li, Jinfei Lin, Jiajia Yang, Yanna Ren
{"title":"Audiovisual integration facilitates age-related perceptual decision-making.","authors":"Xiangfu Yang, Weiping Yang, Ruizhi Li, Jinfei Lin, Jiajia Yang, Yanna Ren","doi":"10.1093/geronb/gbaf037","DOIUrl":"https://doi.org/10.1093/geronb/gbaf037","url":null,"abstract":"<p><strong>Objectives: </strong>Aging populations commonly experience a decline in sensory functions, which negatively affects perceptual decision-making. The decline in sensory functions has been shown to be partially compensated by audiovisual integration. Although audiovisual integration may have a positive effect on perception, it remains unclear whether the perceptual improvements observed in older adults during perceptual decision-making are better explained by the early or late integration hypothesis.</p><p><strong>Methods: </strong>An audiovisual categorization task was used to explore responses to unisensory and audiovisual stimuli in young and older adults. Behavioral drift diffusion model (DDM) and electroencephalography (EEG) were applied to characterize differences in cognitive and neural dynamics across groups.</p><p><strong>Results: </strong>The DDM showed that older adults exhibited higher drift rates and shorter non-decision times for audiovisual stimuli than for visual or auditory stimuli alone. The EEG results showed that during the early sensory encoding stage (150 to 300 ms), older adults exhibited greater audiovisual integration in beta-band than younger adults. In the late decision formation stage (500 to 700 ms), older adults exhibited greater audiovisual integration in beta-band and greater audiovisual integration in the anterior frontal electrodes than younger adults.</p><p><strong>Discussion: </strong>These findings highlight the crucial role of audiovisual integration in both the early and late stages of perceptual decision-making in older adults. The results suggest that enhanced audiovisual integration in older adults compared with younger adults may serve as a specific mechanism to mitigate the negative effects of aging on perceptual decision-making.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards AI-Driven Precision Measurement of Cognition, Behavior, and Psychological Function in Aging and AD/ADRD. 实现人工智能驱动的老龄化和注意力缺陷/注意力缺陷残疾认知、行为和心理功能精确测量。
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-02-28 DOI: 10.1093/geronb/gbaf045
Luke E Stoeckel, Dinesh John, Matthew Sutterer
{"title":"Towards AI-Driven Precision Measurement of Cognition, Behavior, and Psychological Function in Aging and AD/ADRD.","authors":"Luke E Stoeckel, Dinesh John, Matthew Sutterer","doi":"10.1093/geronb/gbaf045","DOIUrl":"https://doi.org/10.1093/geronb/gbaf045","url":null,"abstract":"<p><p>The National Institute on Aging (NIA) is at the forefront of leveraging advances in artificial intelligence (AI) to better understanding of aging and the diagnosis and treatment of Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD). Recent NIA-supported projects have highlighted the transformative potential of AI, digital health, and computational approaches in improving the modeling, detection, and monitoring of changes in healthy aging and AD/ADRD. This perspective is forward looking, emphasizing key areas and efforts in AI-driven precision measurement in cognition, behavior, and psychological function.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association between Disability Status of the Caregivers and Their Perceived Mental Strain: Hong Kong Population-Based Study of Caregivers of Older Adults with Disabilities.
IF 4.8 2区 医学
Journals of Gerontology Series B-Psychological Sciences and Social Sciences Pub Date : 2025-02-27 DOI: 10.1093/geronb/gbaf044
Shan Mao, Tarani Chandola, Vivian Weiqun Lou, Dara Kiu Yi Leung
{"title":"The Association between Disability Status of the Caregivers and Their Perceived Mental Strain: Hong Kong Population-Based Study of Caregivers of Older Adults with Disabilities.","authors":"Shan Mao, Tarani Chandola, Vivian Weiqun Lou, Dara Kiu Yi Leung","doi":"10.1093/geronb/gbaf044","DOIUrl":"https://doi.org/10.1093/geronb/gbaf044","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the association between caregivers' disability status and their mental strain when caring for family members with disabilities. Moreover, we examined the moderating roles of caregiving time and the presence of additional caregivers in this association.</p><p><strong>Methods: </strong>Data were selected from a territory-wide survey of people with disabilities in Hong Kong, which included 85,700 family caregivers of people with disabilities. Logistic regression was adopted to test the study hypotheses. Weights were applied for all analyses to ensure the sample was representative of the population.</p><p><strong>Results: </strong>Caregivers' disability status was associated with higher levels of mental strain among family caregivers of people with disabilities (OR = 2.58, p < .001). More caregiving hours per week predicted higher risks of caregiving mental strain (20.0-39.9 hours: OR = 3.38, p = .005; 40.0-59.9 hours: OR = 5.01, p = .001; 60.0 hours or more: OR = 9.08, p < .001). The presence of additional caregivers did not reduce the mental strain of primary caregivers. Additionally, no significant moderating effects were observed. However, the results suggest that caregivers with disabilities were more sensitive to the adverse effect of more caregiving time on mental strain.</p><p><strong>Discussion: </strong>This study highlights the significant impact of caregivers' disability status on mental strain, underscoring the need for targeted social services and policies to reduce caregiving burdens and protect caregivers' health, especially for those with disabilities.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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