Photoacoustics最新文献_第2页

Efficient implementations of a Born Series for computing photoacoustic field from a collection of erythrocytes 从红细胞集合中计算光声场的博恩数列的高效实现

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-10 DOI: 10.1016/j.pacs.2025.100724

Ujjal Mandal , Navroop Singh , Kartikay Singh , Vinit Nana Hagone , Jagpreet Singh , Anshu S. Anand , Ben T. Cox , Ratan K. Saha

引用次数: 0

Rapid synergistic thrombolysis of ischemic stroke guided by high-resolution and high-speed photoacoustic cerebrovascular imaging 高分辨率、高速光声脑血管成像引导下缺血性脑卒中快速协同溶栓

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-04 DOI: 10.1016/j.pacs.2025.100722

Mengtao Han , Zhiwei Xue , Mengchen Yu , Nanlin You , Yaguang Ren , Zhiqiang Xu , Zhifeng Wu , Yiming He , Zonghai Sheng , Chengbo Liu , Donghai Wang , Jingqin Chen

{"title":"Rapid synergistic thrombolysis of ischemic stroke guided by high-resolution and high-speed photoacoustic cerebrovascular imaging","authors":"Mengtao Han , Zhiwei Xue , Mengchen Yu , Nanlin You , Yaguang Ren , Zhiqiang Xu , Zhifeng Wu , Yiming He , Zonghai Sheng , Chengbo Liu , Donghai Wang , Jingqin Chen","doi":"10.1016/j.pacs.2025.100722","DOIUrl":"10.1016/j.pacs.2025.100722","url":null,"abstract":"<div><div>Thrombosis is the major cause of ischemic stroke and poses a serious health burden globally. Current thrombolytic strategies, such as systematic administration of recombinant human tissue plasminogen activator (rt-PA), are challenged by limited thrombolysis efficiency due to low targeting ability and a short plasma half-life. Here, we report a rapid synergistic strategy that integrates sonothrombolysis and rt-PA mediated pharmacological thrombolysis to achieve accurate and efficient treatment of ischemic stroke. The strategy (PLPA@PFP) uses a platelet-biomimetic membrane as a carrier to deliver both perfluoropentane (PFP) and rt-PA, prolonging half-life and effectively accumulating at the thrombus within 0.5 hours. Upon exposure to focused ultrasound, PFP-based cavitation effects significantly enhance thrombus breakdown and rt-PA penetration, enabling synergistic sono/pharmacological thrombolysis both <em>in vitro</em> and <em>in vivo</em>. High-resolution photoacoustic (PA) imaging provides direct assessment of vascular reperfusion following therapeutic intervention in a murine model of ischemic stroke, offering important guidance for clinical treatment.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"43 ","pages":"Article 100722"},"PeriodicalIF":7.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoacoustic microscopy for studying mechano-transduction response in resistance vessels 用于研究阻力血管机械转导反应的光声显微镜

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-04 DOI: 10.1016/j.pacs.2025.100713

Juliana Benavides-Lara , Dianicha Santana Nunez , Mohsin Zafar , Janette Garcia Campos , Shuangping Zhao , Yulia A. Komarova , Kamran Avanaki

{"title":"Photoacoustic microscopy for studying mechano-transduction response in resistance vessels","authors":"Juliana Benavides-Lara , Dianicha Santana Nunez , Mohsin Zafar , Janette Garcia Campos , Shuangping Zhao , Yulia A. Komarova , Kamran Avanaki","doi":"10.1016/j.pacs.2025.100713","DOIUrl":"10.1016/j.pacs.2025.100713","url":null,"abstract":"<div><div>Cardiovascular diseases are on the rise, presenting a significant global health challenge. The development of methods enabling the detection of alterations in vascular networks is critical for the early diagnosis and treatment of cardiovascular diseases, including peripheral arterial disease, stroke, and hypertension. Here, we use photoacoustic microscopy (PAM), a non-invasive imaging technique, to monitor morphological changes within the skin vessels of chronically hypertensive mice deficient in the mechanosensitive channel Piezo1 in endothelial cells (Piezo1 EC-KO). We show that, compared to control mice (Piezo1 flox/flox), Piezo1 EC-KO mice are characterized by poorer tissue perfusion due to a vasoconstriction of resistance arterioles. We also show the effect of administration of pharmacological agents on vessel vasodilation in the skin of Piezo1-deficient mice and control mice, identifying quantitative differences between the two groups. These results advance our understanding of vascular mechanodynamics and offer potential implications for developing targeted treatments for hypertensive disorders.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"43 ","pages":"Article 100713"},"PeriodicalIF":7.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143807406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Image restoration for ring-array photoacoustic tomography based on an attention mechanism driven conditional generative adversarial network 基于注意力机制驱动的条件生成对抗网络的环形阵光声层析成像技术的图像复原

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-04 DOI: 10.1016/j.pacs.2025.100714

Wende Dong , Yanli Zhang , Luqi Hu , Songde Liu , Chao Tian

引用次数: 0

Dual-modality ultrasound/photoacoustic tomography for mapping tissue oxygen saturation distribution in intestinal strangulation 用于绘制肠绞窄患者组织氧饱和度分布图的双模式超声波/照相声断层成像技术

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-01 DOI: 10.1016/j.pacs.2025.100721

Jie Zhou , Mengchuan Ou , Bo Yuan , Binzi Yan , Xichuan Wang , Shuaiqi Qiao , Yijie Huang , Lian Feng , Lin Huang , Yan Luo

{"title":"Dual-modality ultrasound/photoacoustic tomography for mapping tissue oxygen saturation distribution in intestinal strangulation","authors":"Jie Zhou , Mengchuan Ou , Bo Yuan , Binzi Yan , Xichuan Wang , Shuaiqi Qiao , Yijie Huang , Lian Feng , Lin Huang , Yan Luo","doi":"10.1016/j.pacs.2025.100721","DOIUrl":"10.1016/j.pacs.2025.100721","url":null,"abstract":"<div><div>The strangulation of intestinal obstruction (IO) presents challenges in the assessment of disease progression and surgical decision-making. Intraoperatively, an accurate evaluation of the status of the IO is critical for determining the extent of surgical resection. Dual-modality ultrasound/photoacoustic tomography (US/PAT) imaging has the potential to provide spatially resolved tissue oxygen saturation (SO₂), serving as a valuable marker for IO diagnosis. In this study, US/PAT was utilized for imaging rat models of IO, with the data used for reconstruction, statistical analysis, and distribution evaluation. Results showed that SO₂ decreased with increasing strangulation severity. Notably, the kurtosis and skewness of the SO₂ distribution outperformed SO₂ itself in diagnosis, as they more effectively capture the heterogeneity of SO₂ distribution. Kurtosis reflects distribution concentration, while skewness measures asymmetry, both achieving areas under the receiver operating characteristic curve (AUROC) of 0.969. In conclusion, US/PAT offers a rapid and convenient method for assessing strangulation in IO.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"43 ","pages":"Article 100721"},"PeriodicalIF":7.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143786285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High resolution photoacoustic vascular image reconstruction through the fast residual dense generative adversarial network 基于快速残差密集生成对抗网络的高分辨率光声血管图像重建

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-01 DOI: 10.1016/j.pacs.2025.100720

Yameng Zhang , Hua Tian , Min Wan , Shihao Tang , Ziyun Ding , Wei Huang , Yamin Yang , Weitao Li

{"title":"High resolution photoacoustic vascular image reconstruction through the fast residual dense generative adversarial network","authors":"Yameng Zhang , Hua Tian , Min Wan , Shihao Tang , Ziyun Ding , Wei Huang , Yamin Yang , Weitao Li","doi":"10.1016/j.pacs.2025.100720","DOIUrl":"10.1016/j.pacs.2025.100720","url":null,"abstract":"<div><div>Photoacoustic imaging is a powerful technique that provides high-resolution, deep tissue imaging. However, the time-intensive nature of photoacoustic microscopy (PAM) poses a significant challenge, especially when high-resolution images are required for real-time applications. In this study, we proposed an optimized Fast Residual Dense Generative Adversarial Network (FRDGAN) for high-quality PAM reconstruction. Through dataset validation on mouse ear vasculature, FRDGAN demonstrated superior performance in image quality, background noise suppression, and computational efficiency across multiple down-sampling scales (×4, ×8) compared to classical methods. Furthermore, in the in vivo experiments of mouse cerebral vasculature, FRDGAN achieves the improvement of 2.24 dB and 0.0255 in peak signal-to-noise ratio and structural similarity metrics in contrast to SRGAN, respectively. Our FRDGAN method provides a promising solution for fast, high-quality PAM microvascular imaging in biomedical research.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"43 ","pages":"Article 100720"},"PeriodicalIF":7.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “Robust and compact light-induced thermoelastic sensor for atmospheric methane detection based on a vacuum-sealed subminiature tuning fork” [Photoacoustics 42 (2025) 100691] “基于真空密封的微型音叉的大气甲烷检测用坚固紧凑的光致热弹性传感器”的勘误表[光声学42 (2025)100691]

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-04-01 DOI: 10.1016/j.pacs.2025.100704

Zhijin Shang , Hongpeng Wu , Gang Wang , Ruyue Cui , Biao Li , Ting Gong , Guqing Guo , Xuanbing Qiu , Chuanliang Li , Lei Dong

引用次数: 0

Photodissociation-driven photoacoustic spectroscopy with UV-LEDs for ozone detection 光解驱动光声光谱与uv - led臭氧检测

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-03-29 DOI: 10.1016/j.pacs.2025.100718

Lukas Escher , Thomas Rück , Simon Jobst , Jonas Pangerl , Rudolf Bierl , Frank-Michael Matysik

引用次数: 0

Harnessing evanescent photoacoustic waves for multi-domain imaging 利用倏逝光声波进行多域成像

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-03-29 DOI: 10.1016/j.pacs.2025.100719

Rong Zhou , Liying Zhang , Beibei Li , Jingtao Xiao , Yiheng Xing , Chang Chen , Yuecheng Shen , Hao Shen , Deng Pan , Hongxing Xu

{"title":"Harnessing evanescent photoacoustic waves for multi-domain imaging","authors":"Rong Zhou , Liying Zhang , Beibei Li , Jingtao Xiao , Yiheng Xing , Chang Chen , Yuecheng Shen , Hao Shen , Deng Pan , Hongxing Xu","doi":"10.1016/j.pacs.2025.100719","DOIUrl":"10.1016/j.pacs.2025.100719","url":null,"abstract":"<div><div>Photoacoustic microscopy (PAM) offers a non-invasive imaging method that overcomes the limitations of light scattering in biological tissues by visualizing optical contrast through the detection of photo-generated acoustic signals. While optical microscopy has significantly advanced through the exploration of optical evanescent waves, the potential of evanescent photoacoustic (PA) waves in PAM remains largely unexplored. In this work, we demonstrate the generation and detection of evanescent PA waves in PAM by positioning the sample near an interface, which directs these waves into the far-field beyond the supercritical angle (SA). These SA-PA signals exhibit distinct characteristics, including dependence of intensity on the source depths and symmetry in far-field angular patterns. Leveraging these features, we develop a proof-of-concept for supercritical angle photoacoustic microscopy (SA-PAM), which utilizes evanescent PA waves to enable new PAM functionalities, such as surface topography reconstruction and edge detection. This approach highlights the role of acoustic near-field exploration in advancing PA technology.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"43 ","pages":"Article 100719"},"PeriodicalIF":7.1,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143786122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in optical fiber-based gas sensors utilizing light-induced acoustic/elastic techniques 利用光致声/弹性技术的光纤气体传感器的最新进展

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-03-28 DOI: 10.1016/j.pacs.2025.100715

Yuhui Liu , Yue Qi , Yangjian Cai , Xiaoyi Bao , Song Gao

引用次数: 0