Photoacoustics最新文献

Magneto-photoacoustic coupling: A pathway to optical-resolution electrical conductivity imaging 磁光声耦合：实现光学分辨率电导率成像的途径

IF 6.8 1区医学

Photoacoustics Pub Date : 2025-08-05 DOI: 10.1016/j.pacs.2025.100755

Songqing Xie , Zhuojun Xie , Shuai Na

引用次数: 0

Optoacoustic imaging in lower extremity revascularization: A novel technique to assess perioperative muscle perfusion 光声成像在下肢血运重建术中的应用：评估围手术期肌肉灌注的新技术

IF 6.8 1区医学

Photoacoustics Pub Date : 2025-07-31 DOI: 10.1016/j.pacs.2025.100756

Tim Wittig , Birte Winther , Charlene Reichl , Andrej Schmidt , Dierk Scheinert , Sabine Steiner

{"title":"Optoacoustic imaging in lower extremity revascularization: A novel technique to assess perioperative muscle perfusion","authors":"Tim Wittig , Birte Winther , Charlene Reichl , Andrej Schmidt , Dierk Scheinert , Sabine Steiner","doi":"10.1016/j.pacs.2025.100756","DOIUrl":"10.1016/j.pacs.2025.100756","url":null,"abstract":"<div><h3>Objectives</h3><div>This proof-of-concept study aimed to assess the feasibility of Multispectral Optoacoustic Tomography (MSOT) in evaluating changes in oxygenated hemoglobin (HbO2) levels in muscles of the lower limb before and after lower extremity revascularization (LER).</div></div><div><h3>Methods</h3><div>In 26 patients, HbO2 levels were assessed before and after LER, with follow-up assessing symptom control and patency for up to six months.</div></div><div><h3>Results</h3><div>A significant difference in HbO2 levels was observed between pre- and post-LER in the muscles of the lower limb. In 10 patients, HbO2 levels did not increase following LER, and at the 6-month follow-up, 2 of these patients required target lesion revascularization (TLR) due to restenosis of ≥ 50 % stenosis. In contrast, 16 patients demonstrated increased HbO2 levels post-LER, with no patients requiring TLR at 6-months.</div></div><div><h3>Conclusion</h3><div>This study demonstrates the potential of MSOT to detect changes in tissue perfusion following LER, highlighting its promise as a novel imaging modality for guiding treatment strategies.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100756"},"PeriodicalIF":6.8,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

All-optical in vivo photoacoustic tomography by adaptive multilayer acoustic backpropagation 自适应多层声反向传播的全光体内光声层析成像

IF 6.8 1区医学

Photoacoustics Pub Date : 2025-07-25 DOI: 10.1016/j.pacs.2025.100753

Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeongha Lee

{"title":"All-optical in vivo photoacoustic tomography by adaptive multilayer acoustic backpropagation","authors":"Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeongha Lee","doi":"10.1016/j.pacs.2025.100753","DOIUrl":"10.1016/j.pacs.2025.100753","url":null,"abstract":"<div><div>Photoacoustic tomography (PAT) combines high optical contrast with deep acoustic penetration, making it valuable for biomedical imaging. However, all-optical systems often face challenges in measuring the acoustic wave-induced displacements on rough and dynamic tissues surfaces. We present an all-optical PAT system enabling fast and high-resolution volumetric imaging <em>in vivo</em>. By integrating holographic microscopy with a soft cover layer and coherent averaging, the system detects ultrasound-induced surface displacements over a 10 × 10 mm² area with 0.5 nm sensitivity in 1 s. A novel backpropagation algorithm reconstructs a depth-selective pressure image from two consecutive displacement maps. The coherent summation of these depth-selective pressure images enables the reconstruction of a 3D acoustic pressure image. Using adaptive multilayer backpropagation, we achieve imaging depths of up to 5 mm, with lateral and axial resolutions of 158 µm and 92 µm, respectively, demonstrated through <em>in vivo</em> imaging of mouse vasculature and chicken embryo vessels.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100753"},"PeriodicalIF":6.8,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conductance-photoacoustic spectroscopy for fast and concurrent sensing of hydrogen and hydrocarbons 用于氢和碳氢化合物的快速和同步传感的电导光声光谱

IF 6.8 1区医学

Photoacoustics Pub Date : 2025-07-23 DOI: 10.1016/j.pacs.2025.100752

Ruobin Zhuang , Jianfeng He , Haoyang Lin , Huijian Luo , Leqing Lin , Lihao Wang , Bin Liu , Wenguo Zhu , Yongchun Zhong , Jianhui Yu , Markus Sigrist , Huadan Zheng

{"title":"Conductance-photoacoustic spectroscopy for fast and concurrent sensing of hydrogen and hydrocarbons","authors":"Ruobin Zhuang , Jianfeng He , Haoyang Lin , Huijian Luo , Leqing Lin , Lihao Wang , Bin Liu , Wenguo Zhu , Yongchun Zhong , Jianhui Yu , Markus Sigrist , Huadan Zheng","doi":"10.1016/j.pacs.2025.100752","DOIUrl":"10.1016/j.pacs.2025.100752","url":null,"abstract":"<div><div>Accurate and rapid detection of hydrogen and hydrocarbons is critical for safety and efficiency in modern energy, industrial, and environmental systems. However, selective and simultaneous quantification of these species remains a significant technical challenge. Here, we introduce conductance–photoacoustic spectroscopy (ConPAS), an integrated sensing approach that combines conductance-based resonance modulation with quartz-enhanced photoacoustic spectroscopy in a single device. By bridging a quartz tuning fork (QTF) with a catalytic platinum microwire, ConPAS enables concurrent extraction of hydrogen and hydrocarbon concentrations from a unified electrical signal: hydrogen is quantified by frequency analysis, while hydrocarbon content is determined by amplitude analysis simultaneously. Experiments demonstrate minimum detection limits of 0.69 % for hydrogen, 40.26 ppm for propane, and 133.7 ppm for methane, with millisecond response time and excellent linearity (R² > 0.99). The modular architecture allows flexible adaptation to other analytes via material substitution, offering a scalable and versatile solution for simultaneous, multi-component gas sensing. This work establishes ConPAS as a powerful, calibration-compatible platform for integrated gas analysis in hydrogen-enriched environments, with broad implications for safety monitoring, process control, and advanced energy applications.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100752"},"PeriodicalIF":6.8,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-frequency (> 65 MHz) broadband transparent transducer with ultrathin gold electrode for dual-mode photoacoustic and laser-induced ultrasound microscopy 高频（bbb65 MHz）宽带透明换能器，超薄金电极，用于双模光声和激光诱导超声显微镜

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-07-20 DOI: 10.1016/j.pacs.2025.100751

Sunghun Park , Woongki Hong , Hyeongyu Park , Eunji Lee , Sangwoo Nam , Jinhwan Jung , Jung Ho Hyun , Jaesok Yu , Hongki Kang , Jin Ho Chang

{"title":"High-frequency (> 65 MHz) broadband transparent transducer with ultrathin gold electrode for dual-mode photoacoustic and laser-induced ultrasound microscopy","authors":"Sunghun Park , Woongki Hong , Hyeongyu Park , Eunji Lee , Sangwoo Nam , Jinhwan Jung , Jung Ho Hyun , Jaesok Yu , Hongki Kang , Jin Ho Chang","doi":"10.1016/j.pacs.2025.100751","DOIUrl":"10.1016/j.pacs.2025.100751","url":null,"abstract":"<div><div>For high-performance combined photoacoustic (PA) and Ultrasound (US) microscopy, precise coaxial alignment of the US and laser beams is essential. This can be realized using broadband transparent ultrasound transducers (TUTs). However, the current dual-mode imaging systems encounter significant challenges in simultaneous PA and US data acquisition due to sequential transmission of light and ultrasound and mechanical movement of dual-mode probes, leading to longer acquisition times and potential registration inaccuracies. To overcome these limitations, we propose a recently developed high-frequency broadband TUT with an ultrathin (< 10 nm) gold electrode, achieving a center frequency of 65.6 MHz and a –6 dB bandwidth of 71.6 %. The ultrathin gold electrode facilitates laser-induced ultrasound (LUS), enabling simultaneous acquisition of PA and US images. In vivo experiments demonstrate that LUS imaging can effectively replace conventional US imaging, offering highly efficient dual-mode PA/US imaging with minimized registration errors.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100751"},"PeriodicalIF":7.1,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reconstructing multiple initial pressure and speed of sound distributions simultaneously in photoacoustic tomography 光声层析成像中多重初始声压和声速分布的同时重建

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-07-11 DOI: 10.1016/j.pacs.2025.100748

Miika Suhonen , Felix Lucka , Aki Pulkkinen , Simon Arridge , Ben Cox , Tanja Tarvainen

{"title":"Reconstructing multiple initial pressure and speed of sound distributions simultaneously in photoacoustic tomography","authors":"Miika Suhonen , Felix Lucka , Aki Pulkkinen , Simon Arridge , Ben Cox , Tanja Tarvainen","doi":"10.1016/j.pacs.2025.100748","DOIUrl":"10.1016/j.pacs.2025.100748","url":null,"abstract":"<div><div>Image reconstruction in photoacoustic tomography relies on an accurate knowledge of the speed of sound in the target. However, the speed of sound distribution is not generally known, which may result in artefacts in the reconstructed distribution of initial pressure. Therefore, reconstructing the speed of sound simultaneously with the initial pressure would be valuable for accurate imaging in photoacoustic tomography. Furthermore, the speed of sound distribution could provide additional valuable information about the imaged target. In this work, simultaneous reconstruction of initial pressure and speed of sound in photoacoustic tomography is studied. This inverse problem is known to be highly ill-posed. To overcome this, we study an approach where the ill-posedness is alleviated by utilising multiple photoacoustic data sets that are generated by different initial pressure distributions within the same imaged target. Then, these initial pressure distributions are reconstructed simultaneously with the speed of sound distribution. A methodology for solving this minimisation problem is formulated using a gradient-based iterative approach equipped with bound constraints and a multigrid approach. The methodology was evaluated with numerical simulations. Different approaches for generating multiple initial pressure distributions and their effect on the solution of the image reconstruction problem were studied. The results show that initial pressure and speed of sound can be simultaneously reconstructed from photoacoustic data. Furthermore, utilising multiple initial pressure distributions improves the reconstructions such that the locations of initial pressure and speed of sound inhomogeneities can be better distinguished and image artifacts are reduced.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100748"},"PeriodicalIF":7.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PA OmniNet: A retraining-free, generalizable deep learning framework for robust photoacoustic image reconstruction PA OmniNet：一种用于鲁棒光声图像重建的无需再训练、可推广的深度学习框架

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-07-08 DOI: 10.1016/j.pacs.2025.100740

Olivier J.M. Stam , Kalloor Joseph Francis , Navchetan Awasthi

{"title":"PA OmniNet: A retraining-free, generalizable deep learning framework for robust photoacoustic image reconstruction","authors":"Olivier J.M. Stam , Kalloor Joseph Francis , Navchetan Awasthi","doi":"10.1016/j.pacs.2025.100740","DOIUrl":"10.1016/j.pacs.2025.100740","url":null,"abstract":"<div><div>For clinical translation of photoacoustic imaging cost-effective systems development is necessary. One approach is the use of fewer transducer elements and acquisition channels combined with sparse sampling. However, this approach introduces reconstruction artifacts that degrade image quality. While deep learning models such as U-net have shown promise in reconstructing images from limited data, they typically require retraining for each new system configuration, a process that demands more data and increased computational resources. In this work, we introduce PA OmniNet, a modified U-net model designed to generalize across different system configurations without the need for retraining. Instead of retraining, PA OmniNet adapts to a new system using only a small set of example images (between 4 and 32), known as a context set. This context set conditions the model to effectively remove artifacts from new input images in various sparse sampling photoacoustic imaging applications. We evaluated PA OmniNet against a standard U-net using multiple datasets, including in vivo data from mouse and human subjects, synthetic data, and images captured at different wavelengths. PA OmniNet consistently outperformed the traditional U-net in generalization tasks, achieving average improvements of 8.3% in the Structural Similarity Index, a 11.6% reduction in Root Mean Square Error, and a 1.55 dB increase in Peak Signal-to-Noise Ratio. In 66% of our test cases, the generalized PA OmniNet even outperformed U-net models trained specifically on the new dataset. Code is available at <span><span>https://github.com/olivierstam4/PA_OmniNet</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100740"},"PeriodicalIF":7.1,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wavelet-enhanced residual optimal transport for Mamba-based image restoration in photoacoustic tomography 小波增强残差最优传输在光声断层成像中基于mamba的图像恢复

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-07-07 DOI: 10.1016/j.pacs.2025.100749

Simon C.K. Chan , Bingxin Huang , Hannah H. Kim , Victor T.C. Tsang , Terence T.W. Wong

{"title":"Wavelet-enhanced residual optimal transport for Mamba-based image restoration in photoacoustic tomography","authors":"Simon C.K. Chan , Bingxin Huang , Hannah H. Kim , Victor T.C. Tsang , Terence T.W. Wong","doi":"10.1016/j.pacs.2025.100749","DOIUrl":"10.1016/j.pacs.2025.100749","url":null,"abstract":"<div><div>Photoacoustic tomography (PAT) combines the high contrast of optical imaging with deep tissue penetration via ultrasound detection. However, hardware limitations often cause sparse sampling during image acquisition, resulting in disruptive streak artifacts that many current deep-learning methods fail to remove effectively. In this paper, we introduce Residual Condition Optimal Transport Mamba (RCMamba)—a novel framework that enhances residual optimal transport by integrating wavelet-based analysis with a hybrid multi-scale state space model backbone, specifically designed for sparse PAT image restoration. Our approach makes two primary contributions. First, we propose a wavelet residual-enhanced transport plan that leverages multi-resolution analysis and a novel wavelet coherence penalty to accurately capture the complex, scale-dependent sparsity patterns characteristic of sparse acquisitions. Second, we develop a hybrid multi-scale mamba architecture that uniquely combines window-based and global state space scanning to preserve both fine anatomical details and long-range structural information. Extensive experiments on vessel phantoms and <em>in vivo</em> mouse models across various sampling densities (16, 32, and 64 projections) demonstrate that RCMamba consistently outperforms state-of-the-art techniques in terms of artifact suppression and structural fidelity. RCMamba holds great promise in advancing the clinical potential of sparse-sampling PAT systems for diagnostic imaging and interventional procedures.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100749"},"PeriodicalIF":7.1,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artifacts in photoacoustic imaging: Origins and mitigations 光声成像中的伪影：起源和缓解

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-07-05 DOI: 10.1016/j.pacs.2025.100745

Max T. Rietberg , Janek Gröhl , Thomas R. Else , Sarah E. Bohndiek , Srirang Manohar , Benjamin T. Cox

引用次数: 0

Multi-scenario photoacoustic endoscopy for in vivo functional imaging 用于体内功能成像的多场景光声内窥镜

IF 7.1 1区医学

Photoacoustics Pub Date : 2025-07-05 DOI: 10.1016/j.pacs.2025.100750

Xiao Liang , Yuanlong Zhao , Linyang Li , Hongdian Sun , Wei Qin , Tingting Li , Heng Guo , Weizhi Qi , Lei Xi

{"title":"Multi-scenario photoacoustic endoscopy for in vivo functional imaging","authors":"Xiao Liang , Yuanlong Zhao , Linyang Li , Hongdian Sun , Wei Qin , Tingting Li , Heng Guo , Weizhi Qi , Lei Xi","doi":"10.1016/j.pacs.2025.100750","DOIUrl":"10.1016/j.pacs.2025.100750","url":null,"abstract":"<div><div>Optical endoscopy has been extensively used in clinical screening and diagnosis of internal diseased organs. Photoacoustic endoscopy, one of the rapidest evolving optical endoscopies, combines rich optical contrasts with high spatial acoustic resolving capability at a considerable penetration depth. However, implementing high-speed, large field-of-view photoacoustic endoscopy in arbitrarily shaped biological tracts and cavities remains a challenge. Here, we develop a miniaturized, multi-view photoacoustic endoscope (Multi-PAE) that integrates a micro-optical scanner and a folded optical path within a capsule-sized probe. The probe features multiple interchangeable imaging interfaces in different orientations to image diverse tracts and cavities. We propose a compound double spiral resonant scanning (CDSRS) mechanism to enable the optical scanner to perform stable and uniform resonant scanning over a large field-of-view. We demonstrate the multi-scenario functional imaging applicability of Multi-PAE in rat rectums, rabbit cervices, and entire human oral cavities.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"45 ","pages":"Article 100750"},"PeriodicalIF":7.1,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0