Photoacoustics最新文献

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Spectral analysis of amplitude and phase echoes in picosecond ultrasonics for strain pulse shape determination 用于应变脉冲形状测定的皮秒超声振幅和相位回波的频谱分析
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-29 DOI: 10.1016/j.pacs.2023.100566
Takehiro Tachizaki , Jeremy J. Baumberg , Osamu Matsuda , Motonobu Tomoda , Hirotsugu Ogi , Oliver B. Wright
{"title":"Spectral analysis of amplitude and phase echoes in picosecond ultrasonics for strain pulse shape determination","authors":"Takehiro Tachizaki ,&nbsp;Jeremy J. Baumberg ,&nbsp;Osamu Matsuda ,&nbsp;Motonobu Tomoda ,&nbsp;Hirotsugu Ogi ,&nbsp;Oliver B. Wright","doi":"10.1016/j.pacs.2023.100566","DOIUrl":"https://doi.org/10.1016/j.pacs.2023.100566","url":null,"abstract":"<div><p>We introduce a spectral analysis method in picosecond ultrasonics to derive strain pulse shapes in a opaque sample with known optical properties. The method makes use of both the amplitude and phase of optical transient relative reflectance changes obtained, for example, by interferometry. We demonstrate this method through numerical simulation and by analysis of experimental results for a chromium film.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"34 ","pages":"Article 100566"},"PeriodicalIF":7.9,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71773687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrafast magnetoacoustics in Galfenol nanostructures Galfenol纳米结构中的超快磁声
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-26 DOI: 10.1016/j.pacs.2023.100565
A.V. Scherbakov , T.L. Linnik , S.M. Kukhtaruk , D.R. Yakovlev , A. Nadzeyka , A.W. Rushforth , A.V. Akimov , M. Bayer
{"title":"Ultrafast magnetoacoustics in Galfenol nanostructures","authors":"A.V. Scherbakov ,&nbsp;T.L. Linnik ,&nbsp;S.M. Kukhtaruk ,&nbsp;D.R. Yakovlev ,&nbsp;A. Nadzeyka ,&nbsp;A.W. Rushforth ,&nbsp;A.V. Akimov ,&nbsp;M. Bayer","doi":"10.1016/j.pacs.2023.100565","DOIUrl":"10.1016/j.pacs.2023.100565","url":null,"abstract":"<div><p>Phonons and magnons are prospective information carriers to substitute the transfer of charge in nanoscale communication devices. Our ability to manipulate them at the nanoscale and with ultimate speed is examined by ultrafast acoustics and femtosecond optomagnetism, which use ultrashort laser pulses for generation and detection of the corresponding coherent excitations. Ultrafast magnetoacoustics merges these research directions and focuses on the interaction of optically generated coherent phonons and magnons. In this review, we present ultrafast magnetoacoustic experiments with nanostructures based on the alloy (Fe,Ga) known as Galfenol. We demonstrate how broad we can manipulate the magnetic response on an optical excitation by controlling the spectrum of generated coherent phonons and their interaction with magnons. Resonant phonon pumping of magnons, formation of magnon polarons, driving of a magnetization wave by a guided phonon wavepacket are demonstrated. The presented experimental results have great application potential in emerging areas of modern nanoelectronics.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"34 ","pages":"Article 100565"},"PeriodicalIF":7.9,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213597923001180/pdfft?md5=aa6c42d1293c89fdf684553f60174797&pid=1-s2.0-S2213597923001180-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136159887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning assisted classification of spectral photoacoustic imaging of carotid plaques 颈动脉斑块光谱光声成像的深度学习辅助分类
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100544
Camilo Cano , Nastaran Mohammadian Rad , Amir Gholampour , Marc van Sambeek , Josien Pluim , Richard Lopata , Min Wu
{"title":"Deep learning assisted classification of spectral photoacoustic imaging of carotid plaques","authors":"Camilo Cano ,&nbsp;Nastaran Mohammadian Rad ,&nbsp;Amir Gholampour ,&nbsp;Marc van Sambeek ,&nbsp;Josien Pluim ,&nbsp;Richard Lopata ,&nbsp;Min Wu","doi":"10.1016/j.pacs.2023.100544","DOIUrl":"10.1016/j.pacs.2023.100544","url":null,"abstract":"<div><p>Spectral photoacoustic imaging (sPAI) is an emerging modality that allows real-time, non-invasive, and radiation-free assessment of tissue, benefiting from their optical contrast. sPAI is ideal for morphology assessment in arterial plaques, where plaque composition provides relevant information on plaque progression and its vulnerability. However, since sPAI is affected by spectral coloring, general spectroscopy unmixing techniques cannot provide reliable identification of such complicated sample composition. In this study, we employ a convolutional neural network (CNN) for the classification of plaque composition using sPAI. For this study, nine carotid endarterectomy plaques were imaged and were then annotated and validated using multiple histological staining. Our results show that a CNN can effectively differentiate constituent regions within plaques without requiring fluence or spectra correction, with the potential to eventually support vulnerability assessment in plaques.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100544"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10475504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transfontanelle photoacoustic imaging of intraventricular brain hemorrhages in live sheep 活体绵羊脑室内脑出血的跨腔光声成像
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100549
Juliana Benavides-Lara, Rayyan Manwar, Laura S. McGuire, Md. Tarikul Islam, Anthony Shoo, Fady T. Charbel, Martha G. Menchaca, Amanda P. Siegel, De-Ann M. Pillers, Juri G. Gelovani, Kamran Avanaki
{"title":"Transfontanelle photoacoustic imaging of intraventricular brain hemorrhages in live sheep","authors":"Juliana Benavides-Lara,&nbsp;Rayyan Manwar,&nbsp;Laura S. McGuire,&nbsp;Md. Tarikul Islam,&nbsp;Anthony Shoo,&nbsp;Fady T. Charbel,&nbsp;Martha G. Menchaca,&nbsp;Amanda P. Siegel,&nbsp;De-Ann M. Pillers,&nbsp;Juri G. Gelovani,&nbsp;Kamran Avanaki","doi":"10.1016/j.pacs.2023.100549","DOIUrl":"10.1016/j.pacs.2023.100549","url":null,"abstract":"<div><p>Intraventricular (IVH) and periventricular (PVH) hemorrhages in preterm neonates are common because the periventricular blood vessels are still developing up to 36 weeks and are fragile. Currently, transfontanelle ultrasound (US) imaging is utilized for screening for IVH and PVH, largely through the anterior fontanelle. However for mild hemorrhages, inconclusive diagnoses are common, leading to failure to detect IVH/PVH or, when other clinical symptoms are present, use of second stage neuroimaging modalities requiring transport of vulnerable patients. Yet even mild IVH/PVH increases the risk of moderate-severe neurodevelopmental impairment. Here, we demonstrate the capability of transfontanelle photoacoustic imaging (TFPAI) to detect IVH and PVH in-vivo in a large animal model. TFPAI was able to detect IVH/PVH as small as 0.3 mL in volume in the brain (<em>p</em> &lt; 0.05). By contrast, US was able to detect hemorrhages as small as 0.5 mL. These preliminary results suggest TFPAI could be translated into a portable bedside imaging probe for improved diagnosis of clinically relevant brain hemorrhages in neonates.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100549"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/56/main.PMC10474607.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10507108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging 超声传感器在经颅光声传感和成像中的应用评价
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100556
Thomas Kirchner , Claus Villringer , Jan Laufer
{"title":"Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging","authors":"Thomas Kirchner ,&nbsp;Claus Villringer ,&nbsp;Jan Laufer","doi":"10.1016/j.pacs.2023.100556","DOIUrl":"https://doi.org/10.1016/j.pacs.2023.100556","url":null,"abstract":"<div><p>Photoacoustic imaging through skull bone causes strong attenuation and distortion of the acoustic wavefront, which diminishes image contrast and resolution. As a result, transcranial photoacoustic measurements in humans have been challenging to demonstrate. In this study, we investigated the acoustic transmission through the human skull to design an ultrasound sensor suitable for transcranial PA imaging and sensing. We measured the frequency dependent losses of human cranial bones <em>ex vivo</em>, compared the performance of a range of piezoelectric and optical ultrasound sensors, and imaged skull phantoms using a PA tomograph based on a planar Fabry–Perot sensor. All transcranial photoacoustic measurements show the typical effects of frequency and thickness dependent attenuation and aberration associated with acoustic propagation through bone. The performance of plano-concave optical resonator ultrasound sensors was found to be highly suitable for transcranial photoacoustic measurements.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100556"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Broadband transparent ultrasound transducer with polymethyl methacrylate as matching layer for in vivo photoacoustic microscopy 用于体内光声显微镜的聚甲基丙烯酸甲酯匹配层宽带透明超声换能器
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100548
Jiaming Zhang , Xing Long , Guangjie Zhang , Zhongtian Ma , Wenzhao Li , Yibing Wang , Fan Yang , Riqiang Lin , Changhui Li , Kwok-Ho Lam
{"title":"Broadband transparent ultrasound transducer with polymethyl methacrylate as matching layer for in vivo photoacoustic microscopy","authors":"Jiaming Zhang ,&nbsp;Xing Long ,&nbsp;Guangjie Zhang ,&nbsp;Zhongtian Ma ,&nbsp;Wenzhao Li ,&nbsp;Yibing Wang ,&nbsp;Fan Yang ,&nbsp;Riqiang Lin ,&nbsp;Changhui Li ,&nbsp;Kwok-Ho Lam","doi":"10.1016/j.pacs.2023.100548","DOIUrl":"10.1016/j.pacs.2023.100548","url":null,"abstract":"<div><p>Photoacoustic imaging (PAI) uniquely combines optics and ultrasound, presenting a promising role in biomedical imaging as a non-invasive and label-free imaging technology. As the traditional opaque ultrasound (US) transducers could hinder the transportation of the excitation light and limit the performance of PAI system, piezoelectric transparent ultrasonic transducers (TUTs) with indium tin oxide (ITO) electrodes have been developed to allow light transmission through the transducer and illuminate the sample directly. Nevertheless, without having transparent matching materials with appropriate properties, the bandwidth of those TUTs was generally narrow. In this work, we propose to employ polymethyl methacrylate (PMMA) as the matching layer material to improve the bandwidth of lithium niobate (LN)-based TUTs. The effects of PMMA matching layer on the performance of TUTs have been systematically studied. With the optimized PMMA matching layer, the very wide bandwidth of &gt; 50 % could be achieved for the TUTs even with different transducer frequencies, leading to the great enhancement of axial resolution when compared to the similar reported work. In addition, the imaging performance of the developed TUT prototype has been evaluated in a PAI system and demonstrated by both phantom and <em>in vivo</em> small animal imaging.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100548"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47446360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Light-induced thermoelastic sensor for ppb-level H2S detection in a SF6 gas matrices exploiting a mini-multi-pass cell and quartz tuning fork photodetector 利用微型多通电池和石英音叉光电探测器在SF6气体基质中检测ppb水平H2S的光致热弹性传感器
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100553
Bo Sun , Pietro Patimisco , Angelo Sampaolo , Andrea Zifarelli , Vincenzo Spagnolo , Hongpeng Wu , Lei Dong
{"title":"Light-induced thermoelastic sensor for ppb-level H2S detection in a SF6 gas matrices exploiting a mini-multi-pass cell and quartz tuning fork photodetector","authors":"Bo Sun ,&nbsp;Pietro Patimisco ,&nbsp;Angelo Sampaolo ,&nbsp;Andrea Zifarelli ,&nbsp;Vincenzo Spagnolo ,&nbsp;Hongpeng Wu ,&nbsp;Lei Dong","doi":"10.1016/j.pacs.2023.100553","DOIUrl":"10.1016/j.pacs.2023.100553","url":null,"abstract":"<div><p>We present an optical sensor based on light-induced thermoelastic spectroscopy for the detection of hydrogen sulfide (H<sub>2</sub>S) in sulfur hexafluoride (SF<sub>6</sub>). The sensor incorporates a compact multi-pass cell measuring 6 cm × 4 cm × 4 cm and utilizes a quartz tuning fork (QTF) photodetector. A 1.58 µm near-infrared distributed feedback (DFB) laser with an optical power of 30 mW serves as the excitation source. The sensor achieved a minimum detection limit (MDL) of ∼300 ppb at an integration time of 300 ms, corresponding to a normalized noise equivalent absorption coefficient (NNEA) of 3.96 × 10<sup>−9</sup> W·cm<sup>−1</sup>·Hz<sup>−1/2</sup>. By extending the integration time to 100 s, the MDL can be reduced to ∼25 ppb. The sensor exhibits a response time of ∼1 min for a gas flow rate of 70 sccm.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100553"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46472686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitigating skin tone bias in linear array in vivo photoacoustic imaging with short-lag spatial coherence beamforming 利用短滞后空间相干波束形成减轻线性阵列体内光声成像中的肤色偏差
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100555
Guilherme S.P. Fernandes , João H. Uliana , Luciano Bachmann , Antonio A.O. Carneiro , Muyinatu A. Lediju Bell , Theo Z. Pavan
{"title":"Mitigating skin tone bias in linear array in vivo photoacoustic imaging with short-lag spatial coherence beamforming","authors":"Guilherme S.P. Fernandes ,&nbsp;João H. Uliana ,&nbsp;Luciano Bachmann ,&nbsp;Antonio A.O. Carneiro ,&nbsp;Muyinatu A. Lediju Bell ,&nbsp;Theo Z. Pavan","doi":"10.1016/j.pacs.2023.100555","DOIUrl":"https://doi.org/10.1016/j.pacs.2023.100555","url":null,"abstract":"<div><p>Photoacoustic (PA) imaging has the potential to deliver non-invasive diagnostic information. However, skin tone differences bias PA target visualization, as the elevated optical absorption of melanated skin decreases optical fluence within the imaging plane and increases the presence of acoustic clutter. This paper demonstrates that short-lag spatial coherence (SLSC) beamforming mitigates this bias. PA data from the forearm of 18 volunteers were acquired with 750-, 810-, and 870-nm wavelengths. Skin tones ranging from light to dark were objectively quantified using the individual typology angle (ITA<span><math><mo>°</mo></math></span>). The signal-to-noise ratio (SNR) of the radial artery (RA) and surrounding clutter were measured. Clutter was minimal (e.g., −16 dB relative to the RA) with lighter skin tones and increased to −8 dB with darker tones, which compromised RA visualization in conventional PA images. SLSC beamforming achieved a median SNR improvement of 3.8 dB, resulting in better RA visualization for all skin tones.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100555"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assembly of fluorophore J-aggregates with nanospacer onto mesoporous nanoparticles for enhanced photoacoustic imaging 荧光团j聚集体与纳米间隔组装在介孔纳米颗粒上增强光声成像
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100552
Wujun Xu, Jarkko Leskinen, Teemu Sahlström, Emilia Happonen, Tanja Tarvainen, Vesa-Pekka Lehto
{"title":"Assembly of fluorophore J-aggregates with nanospacer onto mesoporous nanoparticles for enhanced photoacoustic imaging","authors":"Wujun Xu,&nbsp;Jarkko Leskinen,&nbsp;Teemu Sahlström,&nbsp;Emilia Happonen,&nbsp;Tanja Tarvainen,&nbsp;Vesa-Pekka Lehto","doi":"10.1016/j.pacs.2023.100552","DOIUrl":"10.1016/j.pacs.2023.100552","url":null,"abstract":"<div><p>Many fluorophores, such as indocyanine green (ICG), have poor photostability and low photothermal efficiency hindering their wide application in photoacoustic (PA) tomography. In the present study, a supramolecular assembly approach was used to develop the hybrid nanoparticles (Hy NPs) of ICG and porous silicon (PSi) as a novel contrast agent for PA tomography. ICG was assembled on the PSi NPs to form J-aggregates within 30 min. The Hy NPs presented a red-shifted absorption, improved photothermal stability, and enhanced PA performance. Furthermore, 1-dodecene (DOC) was assembled into the NPs as a ‘nanospacer’, which enhanced non-radiative decay for increased thermal release. Compared to the Hy NPs, adding DOC into the Hy NPs (DOC-Hy) increased the PA signal by 83%. Finally, the DOC-Hy was detectable in PA tomography at 1.5 cm depth in tissue phantom even though its concentration was as low as 6.25 µg/mL, indicating the potential for deep tissue PA imaging.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100552"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47747896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A frequency-domain model-based reconstruction method for transcranial photoacoustic imaging: A 2D numerical investigation 一种基于频域模型的经颅光声成像重建方法:二维数值研究
IF 7.9 1区 医学
Photoacoustics Pub Date : 2023-10-01 DOI: 10.1016/j.pacs.2023.100561
Hyungjoo Park , Junjie Yao , Yun Jing
{"title":"A frequency-domain model-based reconstruction method for transcranial photoacoustic imaging: A 2D numerical investigation","authors":"Hyungjoo Park ,&nbsp;Junjie Yao ,&nbsp;Yun Jing","doi":"10.1016/j.pacs.2023.100561","DOIUrl":"https://doi.org/10.1016/j.pacs.2023.100561","url":null,"abstract":"<div><p>Phase aberration caused by the skull is a major barrier to achieving high quality photoacoustic images of human and non-human primates’ brains. To address this issue, time-reversal methods have been used but they are computationally demanding and slow due to relying on solving the full-wave equation. The proposed approach is based on model-based image reconstruction in the frequency-domain to achieve near real-time image reconstruction. The relationship between an imaging region and transducer array elements can be mathematically described as a model matrix and the image reconstruction can be performed by pseudo-inverse of the model matrix. The model matrix is numerically calculated due to the lack of analytical solutions for transcranial ultrasound. However, this calculation only needs to be performed once for a given experimental setup and the same acoustic medium, and is an offline process not affecting the actual image reconstruction time. This non-iterative mode-based method demonstrates a substantial improvement in image reconstruction time, being approximately 18 times faster than the time-reversal method, all while maintaining comparable image quality.</p></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"33 ","pages":"Article 100561"},"PeriodicalIF":7.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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