Youshen Xiao , Yuting Shen , Sheng Liao , Bowei Yao , Xiran Cai , Yuyao Zhang , Fei Gao
{"title":"Limited-view photoacoustic imaging reconstruction via high-quality self-supervised neural representation","authors":"Youshen Xiao , Yuting Shen , Sheng Liao , Bowei Yao , Xiran Cai , Yuyao Zhang , Fei Gao","doi":"10.1016/j.pacs.2025.100685","DOIUrl":null,"url":null,"abstract":"<div><div>In practical applications within the human body, it is often challenging to fully encompass the target tissue or organ, necessitating the use of limited-view arrays, which can lead to the loss of crucial information. Addressing the reconstruction of photoacoustic sensor signals in limited-view detection spaces has become a focal point of current research. In this study, we introduce a self-supervised network termed HIgh-quality Self-supervised neural representation (HIS), which tackles the inverse problem of photoacoustic imaging to reconstruct high-quality photoacoustic images from sensor data acquired under limited viewpoints. We regard the desired reconstructed photoacoustic image as an implicit continuous function in 2D image space, viewing the pixels of the image as sparse discrete samples. The HIS’s objective is to learn the continuous function from limited observations by utilizing a fully connected neural network combined with Fourier feature position encoding. By simply minimizing the error between the network’s predicted sensor data and the actual sensor data, HIS is trained to represent the observed continuous model. The results indicate that the proposed HIS model offers superior image reconstruction quality compared to three commonly used methods for photoacoustic image reconstruction.</div></div>","PeriodicalId":56025,"journal":{"name":"Photoacoustics","volume":"42 ","pages":"Article 100685"},"PeriodicalIF":7.1000,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photoacoustics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213597925000047","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
In practical applications within the human body, it is often challenging to fully encompass the target tissue or organ, necessitating the use of limited-view arrays, which can lead to the loss of crucial information. Addressing the reconstruction of photoacoustic sensor signals in limited-view detection spaces has become a focal point of current research. In this study, we introduce a self-supervised network termed HIgh-quality Self-supervised neural representation (HIS), which tackles the inverse problem of photoacoustic imaging to reconstruct high-quality photoacoustic images from sensor data acquired under limited viewpoints. We regard the desired reconstructed photoacoustic image as an implicit continuous function in 2D image space, viewing the pixels of the image as sparse discrete samples. The HIS’s objective is to learn the continuous function from limited observations by utilizing a fully connected neural network combined with Fourier feature position encoding. By simply minimizing the error between the network’s predicted sensor data and the actual sensor data, HIS is trained to represent the observed continuous model. The results indicate that the proposed HIS model offers superior image reconstruction quality compared to three commonly used methods for photoacoustic image reconstruction.
PhotoacousticsPhysics and Astronomy-Atomic and Molecular Physics, and Optics
CiteScore
11.40
自引率
16.50%
发文量
96
审稿时长
53 days
期刊介绍:
The open access Photoacoustics journal (PACS) aims to publish original research and review contributions in the field of photoacoustics-optoacoustics-thermoacoustics. This field utilizes acoustical and ultrasonic phenomena excited by electromagnetic radiation for the detection, visualization, and characterization of various materials and biological tissues, including living organisms.
Recent advancements in laser technologies, ultrasound detection approaches, inverse theory, and fast reconstruction algorithms have greatly supported the rapid progress in this field. The unique contrast provided by molecular absorption in photoacoustic-optoacoustic-thermoacoustic methods has allowed for addressing unmet biological and medical needs such as pre-clinical research, clinical imaging of vasculature, tissue and disease physiology, drug efficacy, surgery guidance, and therapy monitoring.
Applications of this field encompass a wide range of medical imaging and sensing applications, including cancer, vascular diseases, brain neurophysiology, ophthalmology, and diabetes. Moreover, photoacoustics-optoacoustics-thermoacoustics is a multidisciplinary field, with contributions from chemistry and nanotechnology, where novel materials such as biodegradable nanoparticles, organic dyes, targeted agents, theranostic probes, and genetically expressed markers are being actively developed.
These advanced materials have significantly improved the signal-to-noise ratio and tissue contrast in photoacoustic methods.