Journal of Stomatology Oral and Maxillofacial Surgery最新文献

{"title":"Role of anesthetic techniques in trigeminocardiac reflex during oral surgery of the mandible under local anesthesia","authors":"Bedreddin Cavlı ,&nbsp;Aykut Şaylığ ,&nbsp;Şeyma Kale ,&nbsp;Necmiye Şengel ,&nbsp;Ziver Ergun Yücel","doi":"10.1016/j.jormas.2025.102704","DOIUrl":"10.1016/j.jormas.2025.102704","url":null,"abstract":"<div><h3>İntroduction</h3><div>The trigeminocardiac reflex is a clinically important autonomic response to trigeminal stimulation, particularly characterized by heart rate reduction; however, its behavior under local anesthesia is not well defined. This prospective clinical study investigated the impact of different local anesthesia techniques on the incidence and hemodynamic characteristics of the trigeminocardiac reflex (TCR) during mandibular nerve stimulation in awake patients.</div></div><div><h3>Materials and Methods</h3><div>Forty individuals undergoing surgical extraction of impacted mandibular teeth were enrolled. To minimize vasovagal influence, anxious patients were excluded. Group-1 received a Gow-Gates mandibular nerve block, whereas Group-2 received an inferior alveolar nerve block with supplementary buccal anesthesia. Heart rate (HR) and mean arterial blood pressure (MABP) were continuously monitored throughout local anesthesia administration and all surgical stages.</div></div><div><h3>Results</h3><div>TCR-compatible bradycardia occurred in 30% (12/40) of patients, most frequently during anesthetic injection and mucosal manipulation, including flap elevation, and suturing.A significantly higher incidence of the TCR was observed in Group 1.The maximum HR reduction recorded was 43.5%. The linear progression of stage-specific baseline MABP and HR values showed a significant decrease during curettage/irrigation and suturing.</div></div><div><h3>Conclusion</h3><div>These findings demonstrate that the TCR can occur during oral surgery performed under local anesthesia, typically at mild levels, and that the anesthesia technique influences its incidence. This study contributes to the current literature by evaluating the prophylactic potential of different local anesthesia techniques in oral surgery and by integrating anxiety assessment to enhance methodological robustness.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102704"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Squamous cell carcinoma in the lacrimal sac presenting as proptosis: a case report","authors":"Milan Martinez Sanchez ,&nbsp;Annelies Kerckhofs ,&nbsp;Elke Van de Casteele ,&nbsp;Lukas Vaes ,&nbsp;Wouter De Vos","doi":"10.1016/j.jormas.2026.102711","DOIUrl":"10.1016/j.jormas.2026.102711","url":null,"abstract":"<div><h3>Key Clinical Message</h3><div>Lacrimal sac squamous cell carcinoma is extremely rare, and treatment guidelines remain unclear. In select cases, wide en bloc resection combined with prosthetic rehabilitation may offer the best outcomes. This case report advocates a multidisciplinary, consensus-driven approach centered on patient outcomes, with the use of a 3D printed skull with the benefits of gaining insight and providing visualisation pre-operatively. In addition, we want to emphasise the importance of speed in diagnosis and treatment in this report, in order to ensure optimal care.</div></div><div><h3>Summary</h3><div>Lacrimal sac squamous cell carcinoma is a rare epithelial malignancy often misdiagnosed as chronic dacryocystitis, delaying treatment. This article reports a pT4bN2bM0 case in a 67-year-old man treated with wide en bloc resection, yielding clear margins (&gt;6 mm) and found after 4 months from initial symptoms. A 3D-printed skull model aided preoperative visualization. Histology revealed lymphovascular invasion and broad nests of atypical squamous cells with dyskeratosis and necrosis, confirming lacrimal origin. Adjuvant chemoradiotherapy followed. At 21 months follow-up, no signs of local, regional, or distant recurrence were observed.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102711"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145949492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Impact of the need for dental extractions on oral health-related quality of life in patients with cirrhosis: A cross-sectional study”","authors":"Janaina B. Medina ,&nbsp;Wallena Albuquerque-da-Cunha ,&nbsp;Andrés Blanco-Carrión ,&nbsp;Maria Paula Siqueira de Melo Peres ,&nbsp;Karem L. Ortega ,&nbsp;Juliana Bertoldi Franco","doi":"10.1016/j.jormas.2025.102681","DOIUrl":"10.1016/j.jormas.2025.102681","url":null,"abstract":"<div><h3>Introduction</h3><div>Liver cirrhosis significantly compromises patients’ physical and psychological health, leading to a marked reduction in quality of life (QoL). In addition to systemic complications oral health problems are prevalent and may exacerbate malnutrition, risk of infection, and overall clinical deterioration<strong>.</strong> Oral health–related quality of life (OHRQoL) is increasingly recognized as a relevant outcome in cirrhosis, yet it remains unclear whether acute dental needs, such as tooth extractions, further deteriorate patients’ perceived burden. Poor oral health can be particularly critical in patients awaiting liver transplantation, who often require urgent dental interventions due to infection foci, frequently resulting in multiple tooth extractions. Assessing the impact of oral health on quality of life in this population is essential to support comprehensive pre-transplant care.</div></div><div><h3>Material &amp; Methods</h3><div>A cross-sectional study was conducted with 267 participants, divided into three groups: SG1 (cirrhosis with need for tooth extractions), SG2 (cirrhosis without need for tooth extractions), and CG (controls without cirrhosis). OHRQoL was assessed using the Oral Health Impact Profile (OHIP-14) questionnaire. The 14 items were analyzed according to seven predefined dimensions and a three-factor model. Exploratory factor analysis was performed, and the internal consistency of each factor was assessed using Cronbach’s alpha. Group comparisons were conducted using the Kruskal-Wallis test, followed by Mann-Whitney and Dwass-Steel-Critchlow-Fligner post hoc tests.</div></div><div><h3>Results</h3><div>Factor analysis confirmed the theoretical three-factor model (KMO = 0.888), with satisfactory internal consistency (Cronbach’s α &gt; 0.70 for all factors). Cirrhotic patients showed significantly worse OHRQoL than controls across all OHIP-14 factors (<em>p</em> &lt; 0.001), particularly in the psychological and physical dimensions. No significant differences were found between SG1 and SG2 in overall OHIP-14 scores, although SG1 presented worse scores in specific dimensions such as physical pain and social disability. The need for tooth extractions did not significantly affect overall OHRQoL, which remained moderate in both cirrhotic groups.</div></div><div><h3>Discussion</h3><div>Patients with liver cirrhosis awaiting liver transplantation experience a moderate negative impact of oral health on quality of life, predominantly in psychological and physical dimensions. Although the need for tooth extractions was associated with specific dimension scores, it did not significantly influence overall OHRQoL, suggesting that systemic disease burden plays a major role in patient perception.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102681"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145751971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of immunotherapy in the management of oral squamous cell carcinoma – A systematic review","authors":"Anusree J,&nbsp;Easwaran Ramaswami,&nbsp;Sonali Kadam,&nbsp;Vijayalaxmi Nimma,&nbsp;Siddhi Rane","doi":"10.1016/j.jormas.2026.102722","DOIUrl":"10.1016/j.jormas.2026.102722","url":null,"abstract":"<div><h3>Background</h3><div>Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with high recurrence rates and limited survival benefits from conventional treatments. Immunotherapy has emerged as a promising therapeutic approach, but its role in OSCC remains to be clearly defined.</div></div><div><h3>Objectives</h3><div>To systematically review and synthesize available evidence on the use of immunotherapy in OSCC, focusing on treatment regimens, clinical outcomes, and adverse effects.</div></div><div><h3>Methods</h3><div>A systematic search of PubMed, MEDLINE, Web of Science, Cochrane Library, and Google Scholar was conducted for studies published between January 2000 and December 2024. Eligible studies were case reports or case series involving OSCC patients treated with immunotherapy. Data extraction and quality assessment were performed using Joanna Briggs Institute (JBI) critical appraisal tools.</div></div><div><h3>Results</h3><div>Seventeen studies comprising 20 individual OSCC cases were included. The most common tumor sites were the tongue (30%) and gingiva (30%), with 60% presenting at stage IV. Immunotherapy was used more often as adjuvant therapy (55%) than monotherapy (45%). Pembrolizumab (<em>n</em> = 7) and nivolumab (<em>n</em> = 5) were the most frequently administered agents. complete responses occurred in 50%, partial responses in 20% of cases and progressive disease in 15%. Adverse effects, reported in 75% of cases, ranged from mild dermatologic reactions to severe immune-mediated events.</div></div><div><h3>Conclusions</h3><div>Immunotherapy shows promising clinical activity in OSCC, particularly in combination with conventional treatments, but its optimal use requires further high-quality research.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102722"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillary bone and dento-alveolar changes in cleft lip and palate patients: Total maxillary distraction osteogenesis versus anterior maxillary segmental distraction osteogenesis","authors":"Thinzar Zaw ,&nbsp;Shaohua Song ,&nbsp;Aung Phyo Thu ,&nbsp;Hsu Yin Min ,&nbsp;Minsi Li ,&nbsp;Zhong Wu ,&nbsp;Xuanping Huang","doi":"10.1016/j.jormas.2025.102663","DOIUrl":"10.1016/j.jormas.2025.102663","url":null,"abstract":"<div><div>This study aimed to evaluate maxillary bone and dento-alveolar changes in cleft lip and palate patients after total maxillary distraction osteogenesis (TMDO) and anterior maxillary segmental distraction osteogenesis (AMSDO).</div><div>The retrospective study included 18 cleft lip and palate patients who underwent either with TMDO or AMSDO. CBCT scans of individuals were obtained and measured at predistraction (T1), post distraction (T2). Linear and angular measurements of maxillary bone and dento-alveolar bone were performed using three-dimensional reconstruction images. For intragroup comparisons, a paired <em>t</em>-test or Wilcoxon signed-rank test was used. For intergroup comparisons, an independent <em>t</em>-test or Mann-Whitney U test was used, with the Bonferroni correction applied.</div><div>In sagittal plane, sella-nasion-point A angles (SNA) and overjet increased significantly after distraction osteogenesis in both groups, but greater value was found in TMDO group. Palatal length (ANS-PNS) was significantly increased more in AMSDO group compared to TMDO group. In the vertical plane, Nasion-ptm-point A angles (N-ptm-A) and overbite increased significantly in TMDO, but not in AMSDO. In the axial plane, there was a greater increase of posterior arch width and a decrease in anterior arch width in AMSDO but difference was not statistically significant.</div><div>TMDO is optimal for comprehensive profile correction, while AMSDO is ideal for increasing arch length. The distractor's angulation directly controls the magnitude of arch lengthening and vertical elongation.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102663"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude and predictors of psychological burden of care among informal caregivers of Noma survivors","authors":"A.I. Yakubu ,&nbsp;M. Bala ,&nbsp;R.O. Braimah ,&nbsp;A. Bello ,&nbsp;A. Abubakar ,&nbsp;A.T. Bakare ,&nbsp;H.T. Ismail ,&nbsp;I. Abdulfattah ,&nbsp;I.O. Bruno ,&nbsp;B.A. Sulaiman ,&nbsp;J. Sarki ,&nbsp;I.A. Hadi ,&nbsp;Z. Umar ,&nbsp;A.S. Inuwa ,&nbsp;A.Y. Abbas ,&nbsp;M.I. Gidado ,&nbsp;A.A. Bioku ,&nbsp;A. Abdullahi ,&nbsp;U. Abdullahi ,&nbsp;A.O. Taiwo","doi":"10.1016/j.jormas.2025.102699","DOIUrl":"10.1016/j.jormas.2025.102699","url":null,"abstract":"<div><h3>Background</h3><div>Cancrum Oris is a devastating gangrenous lesion of the orofacial regions that primarily affects the undernourished children, with consequent disfigurement of the face. Noma places a considerable social, psychological, emotional, and financial burden on their informal caregivers. However, this burden on caregivers remains largely understudied. This research aimed to assess the level and predictors of caregiver psychological burden among informal caregivers of Noma patients in Northwestern Nigeria.</div></div><div><h3>Materials and methods</h3><div>This was a cross-sectional study conducted among 92 informal caregivers of Noma survivors attending Noma Children’s Hospital in Sokoto, who were recruited via a universal sampling method over two years<strong>.</strong> Caregiver burden was assessed using the Zarit Burden Interview (ZBI)<strong>.</strong> Data were analyzed using SPSS version 25, with Chi-square tests employed to determine associations and logistic regression used to identify predictors. Statistical significance was set at <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>The mean age of the caregivers was 38.0 years (SD ± 10.1)<strong>;</strong> most were female (84.8%)<strong>,</strong> married (87.0%)<strong>,</strong> and parents of the survivor. The caregivers experienced a mild-to-moderate burden in 47.8% of cases, a moderate-to-severe burden in 47.8%, and a severe burden in 4.4%. Being female (<em>p</em> = 0.0170) and being a parent (<em>p</em> = 0.011) were associated with higher caregiver burden; female sex remained the only independent predictor of high caregiver burden <strong>(</strong><em>p</em> = 0.019)<strong>.</strong></div></div><div><h3>Conclusion</h3><div>Informal caregivers of Noma survivors experience considerable psychological burden, particularly female caregivers and parents of patients. Targeted psychosocial support is necessary to alleviate caregiver strain and enhance care outcomes.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102699"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-analysis comparing the outcomes of immediate versus delayed implant placement under periodontitis conditions","authors":"Jiaqin Wang ,&nbsp;Dingfa Gu ,&nbsp;Fei Sun","doi":"10.1016/j.jormas.2025.102697","DOIUrl":"10.1016/j.jormas.2025.102697","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to compare the outcomes of immediate versus delayed implant placement in patients with periodontitis through a meta-analysis, evaluating differences in restorative outcomes, implant success rate and aesthetics.</div></div><div><h3>Methods</h3><div>A systematic search was conducted across multiple databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure) for relevant randomised controlled trials (RCTs). The inclusion criteria identified patients with severe periodontitis with residual alveolar bone height ≥4 mm post-extraction. Nine RCTs were included, analysing the postoperative probing depth (PD), modified sulcus bleeding index (mSBI), modified plaque index (mPLI), aesthetic outcomes and implant success rate.</div></div><div><h3>Results</h3><div>Postoperative PD: Immediate implantation had significantly higher PD scores than delayed implantation (mean difference [MD] = 0.32, 95% confidence interval [CI] = 0.21–0.43, <em>p</em> &lt; 0.0001). Postoperative mSBI: Immediate implantation showed superior mSBI scores (MD = 0.29, 95% CI = 0.12–0.46, <em>p</em> = 0.001). Postoperative mPLI: Immediate implantation outperformed delayed implantation (MD = 0.61, 95% CI = 0.53–0.69, <em>p</em> &lt; 0.0001). Aesthetic outcomes: Immediate implantation resulted in better aesthetic scores at 3, 6 and 12 months (3 months: MD = 1.80, <em>p</em> &lt; 0.0001; 6 months: MD = 2.42, <em>p</em> = 0.03; 12 months: MD = 1.65, <em>p</em> = 0.04). Implant Success Rate: A significant difference was found in implant success rates between the groups (risk ratio = 1.74, 95% CI = 1.30–2.34, <em>p</em> = 0.0002).</div></div><div><h3>Conclusion</h3><div>Immediate implantation shows significant short-term benefits in patients with periodontitis, particularly in restorative outcomes and aesthetics. Although there is no significant difference in implant success rates, delayed implantation may aid in periodontal tissue recovery. The choice between the two strategies should be tailored to the patient's condition and clinical needs.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102697"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cold atmospheric plasma (CAP) shows strain-dependence against Candida albicans growth on titanium","authors":"Ntombizodwa P. Zwane ,&nbsp;Isak J. van der Walt ,&nbsp;Steve A.S. Olorunju ,&nbsp;Euphemia Sekati ,&nbsp;Adam Shnier ,&nbsp;Deran Reddy","doi":"10.1016/j.jormas.2025.102698","DOIUrl":"10.1016/j.jormas.2025.102698","url":null,"abstract":"<div><h3>Objective</h3><div><strong>:</strong> This study assessed the effect of cold atmospheric plasma (CAP) using argon and oxygen on Candida albicans biofilm growth on titanium.</div></div><div><h3>Methods</h3><div><strong>:</strong> Titanium disks were treated with CAP at 10 and 20 min exposure using argon or oxygen plasma. Typical growth from an unspecified clinical Isolate Test Group (TG) (<em>n</em> = 8 for colony forming culture method, <em>n</em> = 8 for biofilm forming method) and resistant (ATCC 10,231) strain Positive Control (PC) (<em>n</em> = 8 for colony forming culture method, <em>n</em> = 8 for biofilm forming method) were tested. Negative Control (NC) was used, which involved plasma-untreated titanium plates (<em>n</em> = 2 for colony-forming culture method, <em>n</em> = 2 for biofilm-forming method). Colony-forming units (CFU) were counted, inactivation rates calculated, and biofilm quantified using optical density at 495 nm (OD495). ANOVA and two-sample tests were applied.</div></div><div><h3>Results</h3><div><strong>:</strong> Oxygen plasma achieved 100% inactivation of TG, while argon plasma showed partial reduction. For resistant PC, oxygen plasma showed no effect, whereas argon achieved up to 99.5% inactivation. ANOVA revealed that group (TG vs PC) was the only significant factor (<em>p</em> = 0.011). Biofilm formation differed significantly between TG and PC (<em>p</em> = 0.014).</div></div><div><h3>Conclusion</h3><div><strong>:</strong> CAP shows strain-specific antifungal activity against C. albicans. Oxygen plasma effectively inhibited TG but not resistant strains, while argon plasma partially reduced both. CAP may have potential as an adjunctive antifungal strategy.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102698"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual surgical planning and 3D custom-made implants in the management of orbital floor fractures: A case control study","authors":"Stefania Troise ,&nbsp;Federica Calabria ,&nbsp;Raffaele Spinelli ,&nbsp;Silvia De Masi ,&nbsp;Sara Tramontano ,&nbsp;Vincenzo Abbate ,&nbsp;Paola Bonavolontà ,&nbsp;Giovanni Salzano ,&nbsp;Gianluca Renato De Fazio ,&nbsp;Antonio Romano ,&nbsp;Luigi Angelo Vaira ,&nbsp;Giuseppe Consorti ,&nbsp;Carlos Navarro Cuellar ,&nbsp;Giovanni Dell'Aversana Orabona","doi":"10.1016/j.jormas.2026.102718","DOIUrl":"10.1016/j.jormas.2026.102718","url":null,"abstract":"<div><h3>Background</h3><div>Orbital floor fractures are among the most frequent facial injuries, and precise reconstruction is essential to prevent both functional and aesthetic complications. Virtual Surgical Planning (VSP) combined with pre-shaped titanium mesh has transformed orbital reconstruction. This study aimed to evaluate whether VSP-assisted surgery with pre-modeled mesh provides greater accuracy and reduced operative times compared with conventional intraoperative mesh shaping.</div></div><div><h3>Methods</h3><div>A case–control study was performed on 52 patients treated at the “Federico II” University Hospital of Naples for large pure orbital floor fractures. Twenty-four patients (Group A) underwent VSP-assisted reconstruction using a preformed titanium mesh, while twenty-eight patients (Group B) received conventional intraoperative mesh modeling. Operative time, postoperative diplopia, infraorbital sensory disturbance, mesh malposition, screw loosening, and infection were compared in the two groups. Clinical and radiological follow-up was conducted at 12 months.</div></div><div><h3>Results</h3><div>Median operative time was significantly shorter in Group A compared with Group B (55 min [IQR 50–65] vs. 110 min [IQR 98–125]; <em>p</em> &lt; 0.001). Persistent diplopia occurred in 4 % of patients in Group A and 28.6 % in Group B (<em>p</em> = 0.028). Implant malposition was observed exclusively in Group B (25 % vs. 0 %; <em>p</em> = 0.011). Other postoperative complications, including infraorbital nerve alterations, eyelid malposition, wound dehiscence, screw loss, and infection, were more frequent in Group B but did not reach statistical significance. No cases of postoperative ocular motility limitation or iatrogenic fracture were observed in either group.</div></div><div><h3>Conclusions</h3><div>VSP with pre-modeled titanium mesh significantly reduces operative time and postoperative complications, enhancing reconstructive precision and outcomes in orbital floor fracture management. This virtual protocol is useful for reducing the costs and waiting times of custom-made implants, manufactured by external companies.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102718"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nasal irrigation reduces radiation-induced rhinosinusitis in nasopharyngeal carcinoma treated with volumetric modulated arc therapy","authors":"Jiarong Li ,&nbsp;Yanchen Ji ,&nbsp;Zhining Yang ,&nbsp;Baihan Lin ,&nbsp;Ying Zhang ,&nbsp;Renxian Xie","doi":"10.1016/j.jormas.2025.102677","DOIUrl":"10.1016/j.jormas.2025.102677","url":null,"abstract":"<div><h3>Background</h3><div>Nasopharyngeal carcinoma (NPC), prevalent in Southeast Asia and Southern China, is commonly treated with radiotherapy (RT). Volumetric modulated arc therapy (VMAT) improves tumor control but radiation-induced rhinosinusitis (RIRS) remains a major complication. Nasal irrigation shows potential in mitigating mucosal damage, yet evidence in VMAT-treated NPC patients is limited. This study evaluates Nasal irrigation’s efficacy in reducing RIRS incidence in this population.</div></div><div><h3>Methods</h3><div>A retrospective cohort of 195 NPC patients treated with VMAT (2018–2021) was analyzed. Patients were divided into Nasal irrigation (<em>n</em> = 84) and non-Nasal irrigation (<em>n</em> = 111) groups. Baseline characteristics and dosimetric parameters (V20–V70, Dmean, Dmax) of the maxillary sinus were compared. Kaplan-Meier analysis and Cox regression models assessed Nasal irrigation’s impact on RIRS risk, with subgroup analyses stratified by sex, TNM stage, and treatment regimen.</div></div><div><h3>Results</h3><div>Kaplan-Meier analysis showed that the probability of developing RIRS was significantly higher in the group that did not undergo nasal irrigation compared with the NI group (<em>p</em> &lt; 0.001). Multivariate analysis confirmed NI reduced RIRS risk (adjusted HR=0.26, <em>p</em> &lt; 0.001), while allergic rhinitis increased risk (adjusted HR=6.56, <em>p</em> = 0.009). For maxillary sinusitis, NI remained protective (HR=0.29, <em>p</em> &lt; 0.001), and higher V70 dose (≥70 Gy) correlated with elevated risk (HR=1.10, <em>p</em> = 0.007). Subgroup analyses demonstrated consistent benefits across sex, T/N stage, and treatment groups (all interaction <em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>NI reduces radiation-induced rhinosinusitis risk in VMAT-treated NPC patients, independent of baseline characteristics. Allergic rhinitis and high V70 doses independently worsen outcomes. These findings support NI as a simple, effective adjunct to improve post-radiotherapy quality of life.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102677"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145702580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}