Australian Endodontic Journal最新文献_第4页

Comparison Between Human Amniotic Membrane and Biodentine as A Pulp Capping Agent—An In Vitro Tooth Culture Study 人羊膜与生物牙本质盖髓剂的比较——体外牙培养研究。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-04-04 DOI: 10.1111/aej.70068

Sarath Sarathy, Selvakarthikeyan Ulaganathan, Saumya-Rajesh Parashar, Paramesh Viswanathan, Mubeena Sahiba, Alan M. Punoose, Velmurugan Natanasabapathy, Nandini Suresh

{"title":"Comparison Between Human Amniotic Membrane and Biodentine as A Pulp Capping Agent—An In Vitro Tooth Culture Study","authors":"Sarath Sarathy, Selvakarthikeyan Ulaganathan, Saumya-Rajesh Parashar, Paramesh Viswanathan, Mubeena Sahiba, Alan M. Punoose, Velmurugan Natanasabapathy, Nandini Suresh","doi":"10.1111/aej.70068","DOIUrl":"10.1111/aej.70068","url":null,"abstract":"<div>\u0000 \u0000 <p>The objective of the study was to compare the role of Cryopreserved human amniotic membrane (cHAM) for early pulp biomineralisation in comparison to Biodentine using the tooth culture model. This study was conducted in two stages. The first stage aimed to establish the tooth culture model and assess the viability of pulp cells at 28 and 50 days. In the second stage, pulp capping was performed in the tooth culture model using cHAM and Biodentine. A total of 20 freshly extracted teeth (for orthodontic reasons) were used for pulp capping with either cHAM or Biodentine. The samples were evaluated for biomineralisation at 14 and 28 days using micro-computed tomography (micro-CT) and histological analysis. Morphometric data from micro-CT scans were analysed using the Chi-square test. The viability of pulp cells in the tooth culture model was 66.1% at 28 days and 38.4% at 50 days. Pulp capping with cHAM resulted in a thicker and larger volume of mineralisation at 28 days (720 μm, 0.7 mm<sup>3</sup>) compared to Biodentine (630 μm, 0.46 mm<sup>3</sup>). Histological analysis revealed that the dentine formed in the HAM group was homogeneous and continuous, while the Biodentine group showed discontinuous foci of mineralisation in the newly formed hard tissue. Within the study's limitations, it is observed that cHAM induces enhanced early pulpal mineralisation compared to Biodentine.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"449-460"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of an Instrument to Assess Endodontists' Knowledge, Attitudes, and Practices Regarding Cone-Beam Computed Tomography 一种评估牙髓医生关于锥形束计算机断层扫描的知识、态度和实践的仪器的开发和验证。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-03-29 DOI: 10.1111/aej.70075

Lisa Morais Fernandes Oliveira, Francielle Silvestre Verner, Pedro Henrique Berbert de Carvalho, Rafael Binato Junqueira

引用次数: 0

Characterisation of the Mesial Root and Middle Mesial Canal Morphology in Mandibular First Molars: An Ex Vivo Micro-CT Study 下颌第一磨牙近中根和中近中管形态特征的离体显微ct研究。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-01-09 DOI: 10.1111/aej.70056

Nuno Rodrigues dos Santos, Jorge N. R. Martins, Mário Rito Pereira, António Ginjeira

引用次数: 0

Efficacy of Calcium Silicate-Based, Simvastatin, Levofloxacin and Calcium Hydroxide Intracanal Medicaments Against Mature Enterococcus faecalis Biofilm. An In Vitro Study 硅酸钙基、辛伐他汀、左氧氟沙星和氢氧化钙肛管内药物对成熟粪肠球菌生物膜的作用。一项体外研究

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-03-04 DOI: 10.1111/aej.70070

Nadia Saeed Hosny, Sara Gamal Elgamal

{"title":"Efficacy of Calcium Silicate-Based, Simvastatin, Levofloxacin and Calcium Hydroxide Intracanal Medicaments Against Mature Enterococcus faecalis Biofilm. An In Vitro Study","authors":"Nadia Saeed Hosny, Sara Gamal Elgamal","doi":"10.1111/aej.70070","DOIUrl":"10.1111/aej.70070","url":null,"abstract":"<div>\u0000 \u0000 <p>This in vitro study investigated the antibiofilm efficacy of calcium silicate-based, Simvastatin, Levofloxacin and calcium hydroxide intracanal medicaments against mature <i>Enterococcus faecalis</i> biofilm. Ninety dentine specimens were inoculated with <i>Enterococcus faecalis</i> biofilm for three weeks and divided into five groups (<i>n</i> = 18): (1) calcium silicate-based; (2) Simvastatin; (3) Levofloxacin; (4) calcium hydroxide (CH); (5) positive control, no medicament. After two weeks of intracanal medicament application, live/dead bacterial cells were assessed using confocal laser scanning microscopy. The results revealed a statistically significant difference in the percentage of dead bacteria of the four tested groups compared to the positive control group (H = 30.45, <i>p</i> < 0.001). The calcium silicate-based group recorded the highest median (IQR) percentage of dead bacteria at 56.33 (10.03), followed by Simvastatin 44.88 (7.30), CH 41.70 (12.53), Levofloxacin 35.99 (3.78), and the positive control group 3.61 (1.01). These findings suggest that these intracanal medicaments demonstrate promising antibiofilm activity, with further investigations needed.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"461-469"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological and Mechanical Comparison of Eggshell-Derived Hydroxyapatite, Calcium Hydroxide, and Mineral Trioxide Aggregate 蛋壳衍生的羟基磷灰石、氢氧化钙和矿物三氧化物骨料的生物学和力学比较。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-02-25 DOI: 10.1111/aej.70067

Makbule Buse Dundar Sari, Ayse Demiral, Mustafa Gungormus, Nurgul K. Bakirhan, Merve Aksoy

{"title":"Biological and Mechanical Comparison of Eggshell-Derived Hydroxyapatite, Calcium Hydroxide, and Mineral Trioxide Aggregate","authors":"Makbule Buse Dundar Sari, Ayse Demiral, Mustafa Gungormus, Nurgul K. Bakirhan, Merve Aksoy","doi":"10.1111/aej.70067","DOIUrl":"10.1111/aej.70067","url":null,"abstract":"<div>\u0000 \u0000 <p>This study compared the mechanical properties of eggshell-derived hydroxyapatite (ESDHA), mineral trioxide aggregate (MTA), and calcium hydroxide (CH), and evaluated their cytotoxicity using human dental pulp stem cells (HDPSCs). Cement samples were prepared and incubated at 37°C under humid conditions. Cytotoxicity was assessed using extracts collected at different setting periods, followed by real-time cell analysis. Compressive strength was measured at multiple time points. Structural and chemical characterisation was performed using X-ray diffractometry, Raman spectroscopy, scanning electron microscopy, and energy-dispersive spectroscopy. ESDHA and MTA showed no cytotoxic effects, whereas CH exhibited initial cytotoxicity with a doubling time of 42.32 ± 1.69 h on day 1. MTA demonstrated the highest compressive strength (85.6 ± 3.2 MPa at 28 days), followed by ESDHA (18.9 ± 1.4 MPa), while CH had the lowest strength (5.1 ± 0.4 MPa). ESDHA appears to be a promising, cost-effective alternative with favourable cytocompatibility but requires mechanical improvement.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"439-448"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of EDTA Formulations and Activation Methods on Stem Cell Response, Antimicrobial Activity and Dentine Integrity: An In Vitro Study EDTA配方和激活方法对干细胞反应、抗菌活性和牙本质完整性的影响：一项体外研究

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-04-08 DOI: 10.1111/aej.70076

Letycia Accioly Simões Coelho, Laura Ferreira Almeida, Ester Alves Ferreira Bordini, Fernanda Balestrero Cassiano, Mirela Cesar Barros, Talita Tartari, Flaviana Bombarda de Andrade, Diana Gabriela Soares dos Passos, Marco Antonio Hungaro Duarte

{"title":"Impact of EDTA Formulations and Activation Methods on Stem Cell Response, Antimicrobial Activity and Dentine Integrity: An In Vitro Study","authors":"Letycia Accioly Simões Coelho, Laura Ferreira Almeida, Ester Alves Ferreira Bordini, Fernanda Balestrero Cassiano, Mirela Cesar Barros, Talita Tartari, Flaviana Bombarda de Andrade, Diana Gabriela Soares dos Passos, Marco Antonio Hungaro Duarte","doi":"10.1111/aej.70076","DOIUrl":"10.1111/aej.70076","url":null,"abstract":"<div>\u0000 \u0000 <p>This study evaluated the effects of 17% trisodium EDTA and 15% disodium EDTA (EDTAd), with or without activation, on SCAP response, antimicrobial activity and dentine chemical alterations. SCAP viability (Live/Dead) and metabolic activity (Alamar Blue) were assessed, along with antibiofilm and intratubular disinfection against <i>Enterococcus faecalis</i> and <i>Streptococcus mutans</i>, after irrigation with EDTA or EDTAd delivered by conventional irrigation (CI), ultrasonic activation (UA) or diode laser activation (LA). Dentine alterations were analysed by Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). EDTA preserved higher SCAP metabolic activity, particularly at early time points (<i>p</i> < 0.05), while cytotoxicity did not differ among groups. Antibiofilm and intratubular antimicrobial effects were similar across irrigants and activation methods (<i>p</i> > 0.05). EDTAd caused greater alterations in the amide III/phosphate ratio (<i>p</i> < 0.05), with increased smear-layer removal and surface irregularities. EDTA showed greater biological compatibility and fewer dentine alterations, whereas EDTAd induced more pronounced structural changes without antimicrobial differences.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"507-517"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determinants of Vital Pulp Therapy Success in Cariously Exposed Mature Permanent Teeth: An Umbrella Review. 龋齿外露成熟恒牙牙髓治疗成功的决定因素综述。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-03 DOI: 10.1111/aej.70115

Rahul Sharma, Harshita Wadhwa, Kanaga Durga, Chanakya Soma

{"title":"Determinants of Vital Pulp Therapy Success in Cariously Exposed Mature Permanent Teeth: An Umbrella Review.","authors":"Rahul Sharma, Harshita Wadhwa, Kanaga Durga, Chanakya Soma","doi":"10.1111/aej.70115","DOIUrl":"https://doi.org/10.1111/aej.70115","url":null,"abstract":"<p><p>Vital pulp therapy (VPT) is a biologically conservative alternative to root canal treatment in mature permanent teeth; however, variability in success rates and uncertainty regarding prognostic and procedural factors necessitate higher-order evidence synthesis. This umbrella review aimed to synthesize systematic reviews evaluating determinants of VPT outcomes in cariously exposed mature permanent teeth, and to appraise methodological quality and primary study overlap. Electronic searches across major databases and grey literature were conducted. Methodological quality was assessed using AMSTAR-2, and overlap quantified using the corrected covered area (CCA). Fourteen reviews were included, with moderate overlap and predominantly low to critically low confidence. Material-related factors showed the most consistent association, with hydraulic calcium silicate-based materials reporting higher success. Other factors showed inconsistent or non-significant effects. Delayed restoration reduced success, and follow-up duration influenced outcomes. Material selection appears the most consistent determinant, although overall evidence certainty remains limited. Trial Registration: International Prospective Register of Systematic Reviews (PROSPERO) CRD420251275599.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Influencing the Outcome of Iatrogenic Perforation Repair in Permanent Teeth-A Narrative Review. 影响恒牙医源性牙穿孔修复效果的因素综述。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-01 Epub Date: 2026-03-08 DOI: 10.1111/aej.70069

Saravanan Poorni, Srividhya Srinivasan, Thomas Clauder, Manali Ramakrishnan Srinivasan, Paul M H Dummer, Venkateshbabu Nagendrababu

引用次数: 0

Artificial Intelligence in Endodontics-A Bibliometric Analysis. 牙髓学中的人工智能——文献计量学分析。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-01 Epub Date: 2026-04-21 DOI: 10.1111/aej.70080

Eric Chen, Justin Jun-Young Eun, Alan Chen, Sepanta Hosseinpour, Hossein Mohammad-Rahimi, Ove Andreas Peters, Philip Yuan-Ho Chien

{"title":"Artificial Intelligence in Endodontics-A Bibliometric Analysis.","authors":"Eric Chen, Justin Jun-Young Eun, Alan Chen, Sepanta Hosseinpour, Hossein Mohammad-Rahimi, Ove Andreas Peters, Philip Yuan-Ho Chien","doi":"10.1111/aej.70080","DOIUrl":"10.1111/aej.70080","url":null,"abstract":"<p><p>This study aims to map and evaluate research trends in artificial intelligence applied to endodontics using bibliometric methods. A comprehensive literature search was conducted in PubMed, EMBASE, and Scopus in April 2025 to identify studies addressing artificial intelligence in endodontic diagnosis, treatment, and education. Titles, abstracts, and full texts were screened according to predefined criteria. Bibliometric indicators including publication output, authorship networks, institutional and country contributions, citation patterns, and keyword co-occurrence were analysed using bibliometric software. 220 studies were included. Research output increased markedly over time, with major contributions from China, the United States, Turkey and India. Collaboration was largely geographically clustered, with limited international integration. Recent publications showed a strong focus on deep learning approaches for diagnostic imaging, particularly cone-beam computed tomography and image segmentation. Artificial intelligence research in endodontics is expanding rapidly, but broader collaboration and diversification beyond radiographic applications are needed to support clinical translation.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":"619-629"},"PeriodicalIF":1.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13436042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spin and Methodological Quality of Systematic Reviews and Meta-Analyses Comparing Single- and Multiple-Visit Endodontic Treatment: A Meta-Research Study. 比较单次和多次就诊根管治疗的系统评价和荟萃分析的旋转和方法质量：一项荟萃研究。

IF 1.7 4区医学

Australian Endodontic Journal Pub Date : 2026-08-01 Epub Date: 2026-05-22 DOI: 10.1111/aej.70087

Ana Luiza Cardoso Pires, Laylla Galdino-Santos, Bas Loomans, Tatiana Pereira-Cenci, Luiz Alexandre Chisini, Fernanda Geraldo Pappen

{"title":"Spin and Methodological Quality of Systematic Reviews and Meta-Analyses Comparing Single- and Multiple-Visit Endodontic Treatment: A Meta-Research Study.","authors":"Ana Luiza Cardoso Pires, Laylla Galdino-Santos, Bas Loomans, Tatiana Pereira-Cenci, Luiz Alexandre Chisini, Fernanda Geraldo Pappen","doi":"10.1111/aej.70087","DOIUrl":"10.1111/aej.70087","url":null,"abstract":"<p><p>This study evaluated the methodological quality and presence of spin in systematic reviews with meta-analyses comparing single-visit and multiple-visit endodontic treatment, and investigated factors associated. Systematic reviews of randomised clinical trials were included without restrictions on language or publication year. Narrative reviews, reviews without meta-analysis, non-randomised or non-clinical studies, and conference abstracts were excluded. A comprehensive search was conducted in PubMed, Scopus, Web of Science, the Cochrane Library and grey literature in January 2025. Spin was classified using the Yavchitz et al. framework, and methodological quality was assessed with AMSTAR 2. Data extraction and spin assessment were performed independently and in duplicate. Thirteen systematic reviews were included. Spin was identified in 12 studies of abstracts and 10 of full texts, mainly as a misleading interpretation. Most reviews were rated as low or critically low quality. Positive results and absence of risk-of-bias assessment were associated with increased spin in full texts.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":"654-665"},"PeriodicalIF":1.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13436167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0