{"title":"Effect of Troughing on the Identification of the Second Mesiobuccal Canals With and Without Calcifications in Maxillary First Molars","authors":"İlker Dinçer Ertürk, Ali Keleş, Cangül Keskin","doi":"10.1111/aej.12922","DOIUrl":"10.1111/aej.12922","url":null,"abstract":"<div>\u0000 \u0000 <p>This study tested the impact of troughing on the detection rates of MB2 canals with and without calcifications. Traditional access cavities were prepared and the detection of MB2 canals was recorded in 200 maxillary molars selected based on micro-CT scans. In specimens, the MB2 orifice was not detected; troughing was performed. The number of negotiated MB2 with and without troughing was compared with micro-CT using McNemar's test. After traditional access cavity preparation without troughing, the operator detected MB2 in 142 specimens (82%). Troughing of the remaining specimens led to the further identification of 16 MB2 canals, increasing detection rate to 91%. Troughing significantly improved the detection rate of non-calcified MB2s (<i>p</i> < 0.05) but did not significantly impact the detection of calcified MB2 canals (<i>p</i> > 0.05). While troughing is highly effective in enhancing MB2 canal detection in non-calcified canals, it may be limited in cases where calcification is present.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"150-154"},"PeriodicalIF":1.3,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Laura Schauenberg Machado, Patrícia Maria Poli Kopper, Maurício Denicol Anastacio, Marcus Vinícius Reis Só, Patrícia Weidlich, Roberta Kochenborger Scarparo
{"title":"Apical Surgery and Resurgery After Recurrent Failure in Traumatised Immature Teeth: Reflections on Management Based on Two Case Reports","authors":"Ana Laura Schauenberg Machado, Patrícia Maria Poli Kopper, Maurício Denicol Anastacio, Marcus Vinícius Reis Só, Patrícia Weidlich, Roberta Kochenborger Scarparo","doi":"10.1111/aej.12921","DOIUrl":"10.1111/aej.12921","url":null,"abstract":"<div>\u0000 \u0000 <p>This study reports two cases of traumatised non-vital immature teeth (IT). Both underwent surgical and nonsurgical treatments after healing failure. In the first case, both maxillary central incisors underwent revascularization as the first treatment option. Failure was detected in tooth #8 after 15 months, while tooth #9 showed periapical healing and further root development. Apical microsurgery was performed because of persistent cystic fluid during nonsurgical retreatment. In the second case, there was recurrent endodontic treatment failure in tooth #9 after nonsurgical mineral trioxide aggregate (MTA) apical plug placement and apical surgery (AS). Endodontic resurgery comprised debridement, apical and lateral root surface planning and removal of remaining MTA from the bone lesion. For both cases, histopathological examination revealed the presence of inflammatory cysts. Periapical healing was observed 1 year after treatment. Apical surgery, and even resurgery, should be considered as alternatives to tooth extraction in growing patients with IT and recurrent healing failure.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"173-180"},"PeriodicalIF":1.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felipe Immich, Tina Rödig, Philipp Kanzow, Evandro Piva, Giampiero Rossi-Fedele
{"title":"Effectiveness of Root Canal Irrigation and Dressing for the Treatment of Asymptomatic Apical Periodontitis: A Systematic Review Assessing Complementary Timeframes","authors":"Felipe Immich, Tina Rödig, Philipp Kanzow, Evandro Piva, Giampiero Rossi-Fedele","doi":"10.1111/aej.12918","DOIUrl":"10.1111/aej.12918","url":null,"abstract":"<p>Sodium hypochlorite (NaOCl), ethylenediaminetetraacetic acid (EDTA), and calcium hydroxide (Ca(OH)<sub>2</sub>) are used in root canal treatment. However, further research is needed to assess their effectiveness at time points not considered in previous guidelines. This review complements the systematic review by Rossi-Fedele and Rödig (2023) by considering time points excluded by the latter. A search was conducted in PubMed-MEDLINE, Scopus, EMBASE, Google Scholar, and repositories between March and May 2024. Four studies met the inclusion criteria, providing data from 212 teeth for irrigation and 108 for dressings. No significant differences in pain reduction within 7 days or radiographic reduction of apical lesion size were found between 2% chlorhexidine, 5.25% NaOCl, EDTA, and various NaOCl concentrations. Single and multiple visit protocols also showed no significant differences in postoperative pain. Two studies had a ‘low risk’ of bias and two ‘some concerns’. Evidence suggests that Ca(OH)<sub>2</sub> dressings may not offer additional benefits.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"209-217"},"PeriodicalIF":1.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/aej.12918","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiliang Yang, Lingyun Xia, Yongji Chen, Lei Jiang, Tianxia Zheng, Yuhong Bai
{"title":"Cytotoxicity and Bone Biocompatibility of the C-Root SP Experimental Root Canal Sealer","authors":"Xiliang Yang, Lingyun Xia, Yongji Chen, Lei Jiang, Tianxia Zheng, Yuhong Bai","doi":"10.1111/aej.12916","DOIUrl":"10.1111/aej.12916","url":null,"abstract":"<div>\u0000 \u0000 <p>This study evaluated the cytotoxicity and biocompatibility of a new strontium silicate-based root canal sealer (C-Root SP), in comparison with those of iRoot SP and AH plus. The sealer extract was diluted to the concentrations of 100%, 75%, 50%, and 25%. L929 cells were cultured for 24 h, and the absorbance value was determined. Two-way analysis of variance (two-way ANOVA) and sealers were implanted in the tibia of Sprague–Dawley (SD) rats, At 2, 6, and 12 weeks, rats were euthanised. The tissue reaction was evaluated by HE staining. The least significant difference (LSD) <i>t</i>-test and Kruskal–Wallis test were used. The cytotoxicity of C-Root SP and iRoot SP was found to be less than that of AH plus. At 12 weeks, new bone formation was induced around C-Root SP and iRoot SP sealer, but minimal evidence of bone formation was found in AH plus. C-Root SP has low cytotoxicity and superior biocompatibility.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"124-132"},"PeriodicalIF":1.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yudi Deng, Jinglan Zhang, Xinran Wang, Lei Yang, Qiang He, Dingming Huang D.D.S., Xuelian Tan Ph.D., D.D.S
{"title":"A bibliometric analysis of root canal irrigation: From laboratory to clinical practice","authors":"Yudi Deng, Jinglan Zhang, Xinran Wang, Lei Yang, Qiang He, Dingming Huang D.D.S., Xuelian Tan Ph.D., D.D.S","doi":"10.1111/aej.12909","DOIUrl":"10.1111/aej.12909","url":null,"abstract":"<p>The study aims to conduct a bibliometric analysis on root canal irrigation to elucidate the development of this domain and pose the future research trends. Of 6722 articles retrieved from Clarivate Analytics' Web of Science Core Collection and PubMed, 6650 publications were included for bibliometric analysis. Irrigation field had received emerging attention for the last half century, peaking at 399 in 2022. The United States was revealed as the most influential contributor, with Journal of Endodontics representing the most voluminous resource. Franklin R Tay was regarded as the most productive author, while Siqueira, Jose. F. was the most prominent. Both keywords cluster analysis and burst analysis revealed the main research branch fields were irrigation protocols. Within this branch, the discussion of irrigants (with a frequency of 1135) ranked first. This bibliometric study revealed the research hotspot of irrigants, while suggesting the future directions of irrigants' creations and micro-level mechanism elucidation.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"197-208"},"PeriodicalIF":1.3,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia García-Guerrero DDS, MSc, Ana Priscila Rodas Serrano DDS, Maria Carolina Leal Fernández DDS, Sara Quijano-Guauque DDS, MSc
{"title":"In vitro bioactive dentin protein release by diode laser conditioning","authors":"Claudia García-Guerrero DDS, MSc, Ana Priscila Rodas Serrano DDS, Maria Carolina Leal Fernández DDS, Sara Quijano-Guauque DDS, MSc","doi":"10.1111/aej.12911","DOIUrl":"10.1111/aej.12911","url":null,"abstract":"<p>This in-vitro study aimed to explore the potential of Diode Laser by quantifying the release of transforming growth factor-beta 1 (TGF-β1), platelet-derived growth factor (PDGF)-BB, and vascular endothelial growth factor (VEGF) from root dentin after ethylenediaminetetraacetic acid (EDTA) and diode laser. In 30 hemi-roots distributed into five groups: G1: Tris-buffered solution (TBS); G2: 17%EDTA; G3: 17% EDTA +650 nm Diode Laser; G4:17% EDTA +810 nm Diode Laser; and G5: 810 nm Diode Laser. The concentration of the three factors was quantified using a cytokine bead array. Statistical tests were performed to estimate intergroup differences (<i>p</i> ≤ 0.05). TGF-β1 and VEGF were solubilised in all test protocols. The ability of low-level power diode lasers to release proteins from the matrix is limited. Its effect on the release of VEGF and PDGF-BB does not make a difference. A synergy between EDTA and Diode Laser led to a greater proportion of TGF-β1 release.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"115-123"},"PeriodicalIF":1.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gokul Gunasekaran, Manavalan Madhana Madhubala MDS, G. S. Nayanthara, Sekar Mahalaxmi
{"title":"Photodynamic antibacterial evaluation of polydopamine nanoparticle optimised Curcumin Longa against endodontic biofilm—An in-vitro study","authors":"Gokul Gunasekaran, Manavalan Madhana Madhubala MDS, G. S. Nayanthara, Sekar Mahalaxmi","doi":"10.1111/aej.12910","DOIUrl":"10.1111/aej.12910","url":null,"abstract":"<p>This study aims to evaluate the effect of antimicrobial photodynamic therapy(aPDT) with polydopamine nanoparticle functionalised with <i>Curcuma longa</i>(nPD-Cur) against root canal biofilm. nPD-Cur was prepared and characterised using Scanning Electron Microscopy(SEM), dynamic light scattering(DLS), Fourier-transform infrared spectroscopy(FTIR) and Ultraviolet visual(UV/Vis) spectrophotometry. Root sections (10 mm length) were obtained from 53 single-rooted human premolars and chemo-mechanically prepared followed by inoculation with <i>E. faecalis</i>. All the specimens were randomly divided into five groups(<i>n</i> = 10) and irrigated (Group 1—Saline; Group 2—2.5% Sodium hypochlorite(NaOCl); Group 3—Cur; Group 4—nPD; and Group 5—nPD-Cur) followed by diode irradiation and analysed for reduction in colony-forming units(CFU)/mL, bacterial viability using Confocal Laser Scanning Microscopy(CLSM) and SEM for biofilm disruption. Results were analysed using one-way ANOVA followed by post hoc Tukey's test for pairwise comparison (<i>p</i> < 0.05). nPD-Cur revealed the characteristic absorption patterns. The antimicrobial potency was highest for NaOCl followed by nPD > Cur-nPD > Cur.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"90-102"},"PeriodicalIF":1.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kivanc Dulger Asst. Prof., Tugba Kosar Asst. Prof.
{"title":"Comparison of three dentine replacement materials in terms of different characteristics","authors":"Kivanc Dulger Asst. Prof., Tugba Kosar Asst. Prof.","doi":"10.1111/aej.12908","DOIUrl":"10.1111/aej.12908","url":null,"abstract":"<p>This in vitro study evaluated three dentine replacement materials: Biodentine, Ketac Molar and TheraBaseCa. Specimens of each material (<i>n</i> = 19) were prepared for investigations of hardness, calcium release, pH and water sorption–solubility. SEM and EDX analysis were also used for these investigations. One-way ANOVA and robust ANOVA tests were used for normally and non-normally distributed data for statistical analysis, respectively. TheraBaseCa showed the lowest hardness (<i>p</i> < 0.001), while Biodentine had the highest pH and calcium release (<i>p</i> < 0.001). Significant differences in water sorption–solubility were observed as Biodentine>Ketac Molar>TheraBaseCa (<i>p</i> < 0.001). SEM and EDX revealed that Biodentine had a crystalline structure with O, Ca, C, Si and Bi; Ketac Molar had a particulate matrix with O, C, F, Ca, Si and Al; and TheraBaseCa had a matrix with C, O, Si, Yb, Al and Ca. In conclusion, Biodentine was more alkaline and released more calcium, while TheraBaseCa had the lowest water sorption—solubility over 28 days.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"81-89"},"PeriodicalIF":1.3,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dina Ahmed Morsy BDS, MSc, PhD, Olfat Gameel Shaker BDS, MSc, PhD, Sherif Adel ElKhodary BDS, MSc, PhD
{"title":"Effect of diode laser (980 nm) on IL-8 expression in failed endodontic cases: Randomised control trial","authors":"Dina Ahmed Morsy BDS, MSc, PhD, Olfat Gameel Shaker BDS, MSc, PhD, Sherif Adel ElKhodary BDS, MSc, PhD","doi":"10.1111/aej.12914","DOIUrl":"10.1111/aej.12914","url":null,"abstract":"<p>This clinical study assessed the effectiveness of diode laser–980 nm as adjuvant in retreatment of failed endodontic cases with chronic periapical lesions on basis of IL-8 expression and postoperative pain when compared to placebo. For 28 patients, the pre-instrumentation periapical samples (S1) were gathered, following retreatment. After chemo-mechanical preparation, post-instrumentation samples (S2) were collected. Patients were allocated to diode laser (DL) or placebo (PL) groups. After which post-irradiation samples (S3) were gathered. Patients recorded their pain on NRS scale at 6, 12, 24 and 7 days. After 1 week, samples (S4) were collected. An ELISA kit was used to measure an amount of IL-8. DL group showed significantly lower IL-8 levels at S4 (<i>p</i> < 0.001) and postoperative pain at 6 h (<i>p =</i> 0.003) compared to PL. Intracanal diode laser irradiation is a beneficial adjunct to endodontics, in retreatment cases regarding reducing postoperative pain and lowering the level of IL-8 expression.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"17-25"},"PeriodicalIF":1.3,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luciana Maria Arcanjo Frota DDS, MSc, PhD, Bernardo Almeida Aguiar DDS, MSc, PhD, Suyane Maria Luna-Cruz DDS, MSc, PhD, Ana Grasiela Limoeiro DDS, MSc, PhD, Murilo Priori Alcalde DDS, MSc, PhD, Rodrigo Ricci Vivan DDS, MSc, PhD, Marco Antonio Hungaro Duarte DDS, MSc, PhD, Bruno Carvalho de Vasconcelos DDS, MSc, PhD
{"title":"In vitro evaluation of the influence of ultrasonic activation on physicochemical properties of three endodontic repair materials","authors":"Luciana Maria Arcanjo Frota DDS, MSc, PhD, Bernardo Almeida Aguiar DDS, MSc, PhD, Suyane Maria Luna-Cruz DDS, MSc, PhD, Ana Grasiela Limoeiro DDS, MSc, PhD, Murilo Priori Alcalde DDS, MSc, PhD, Rodrigo Ricci Vivan DDS, MSc, PhD, Marco Antonio Hungaro Duarte DDS, MSc, PhD, Bruno Carvalho de Vasconcelos DDS, MSc, PhD","doi":"10.1111/aej.12912","DOIUrl":"10.1111/aej.12912","url":null,"abstract":"<p>The influence of ultrasonic activation (UA) on the physicochemical properties of setting time (<i>n</i> = 5), volumetric stability (<i>n</i> = 10), alkalizing activity/calcium ions release (pH/Ca<sup>2+</sup>) (<i>n</i> = 10) and calcium/phosphate-rich substance formation in simulated body fluid (Hank's balanced salt solution; HBSS) of three cements was evaluated: white MTA-Angelus (MTA), MTA Repair HP (MTAHP) and Biodentine (BIO). It was observed that UA influenced the setting times (min) distinctly, delaying the initial setting time of MTA (40.8/64.6) and accelerating that of BIO (35.6/22.4). The final setting time of MTAHP (154.4/114.6) and BIO (64.4/42.4) were also accelerated (<i>p</i> < 0.05). Volumetric reduction was observed in all groups, with MTA/UA being the most volumetrically stable (0.98%); UA did not influence volumetric stability (<i>p</i> > 0.05). All groups exhibited an alkaline pH, with a disadvantage for MTAHP and MTAHP/UA at 24 h, 72 h and 168 h (<i>p</i> < 0.05). All groups showed Ca<sup>2+</sup> release. The tested cements exhibited a favourable Ca/P ratio on their surface after 28 days.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"103-114"},"PeriodicalIF":1.3,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}