Australian Endodontic Journal最新文献

Healing and Skeletal Development Outcomes of a Complex Case Involving Complicated Crown-Root Fracture and Luxation Injuries With a 4-Year Follow-Up. 1例复杂冠根骨折和脱位损伤的愈合和骨骼发育结果，随访4年。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2025-08-01 DOI: 10.1111/aej.12969

Haojie Yu, Fan Yang, Xiaoxia Li, Mengxin Tian, Yaoqiong Wang, Haihua Zhu, Fudong Zhu

{"title":"Healing and Skeletal Development Outcomes of a Complex Case Involving Complicated Crown-Root Fracture and Luxation Injuries With a 4-Year Follow-Up.","authors":"Haojie Yu, Fan Yang, Xiaoxia Li, Mengxin Tian, Yaoqiong Wang, Haihua Zhu, Fudong Zhu","doi":"10.1111/aej.12969","DOIUrl":"https://doi.org/10.1111/aej.12969","url":null,"abstract":"The management of complicated crown-root fractures of immature permanent teeth requires a multidisciplinary approach to address biological, functional, and aesthetic concerns. A 10-year-old boy suffered a complicated crown-root fracture of tooth 11, an uncomplicated crown fracture, subluxation and pulp necrosis of tooth 21 and subluxation of tooth 22 after falling from a bicycle. The treatment for tooth 11 involved maintaining pulp vitality with partial pulpotomy and re-attachment of the crown-root fragment after modified crown-lengthening surgery. Treatment for tooth 21 included a flexible splint, root canal therapy, placement of an apical barrier and resin composite restoration. During the 4-year follow-up, the root of tooth 11 fully developed, and the patient remained asymptomatic and achieved an aesthetically acceptable outcome. Conservative partial pulpotomy followed by adhesive reattachment of the tooth fragment with the modified crown lengthening technique can be a viable treatment for complicated crown-root fractures in immature permanent teeth.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Postoperative Pain After Single- or Multiple-Visit Endodontic Therapy and Its Molecular Aspects: A Randomised Controlled Study. 评估单次或多次牙髓治疗后的术后疼痛及其分子方面：一项随机对照研究。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2025-08-01 DOI: 10.1111/aej.12982

Larissa Nunes Rosa Bedene, Denise Piotto Leonardi, Joana Santana Couto, Bruno Marques-da-Silva, Marilisa Carneiro Leão Gabardo, João Arnando Brancher, Flávia Sens Fagundes Tomazinho

{"title":"Assessment of Postoperative Pain After Single- or Multiple-Visit Endodontic Therapy and Its Molecular Aspects: A Randomised Controlled Study.","authors":"Larissa Nunes Rosa Bedene, Denise Piotto Leonardi, Joana Santana Couto, Bruno Marques-da-Silva, Marilisa Carneiro Leão Gabardo, João Arnando Brancher, Flávia Sens Fagundes Tomazinho","doi":"10.1111/aej.12982","DOIUrl":"https://doi.org/10.1111/aej.12982","url":null,"abstract":"This study aimed to compare patients' perception of postoperative pain following single- and multiple-visit endodontic therapy, and to evaluate associations between anxiety and genetic polymorphisms in the DRD2, ANKK1 and COMT genes. In this clinical trial, 67 patients were included in the first phase (34 single visit, 33 multiple visits), and 25 participated in the second phase. Saliva was collected for genetic analysis, and the State-Trait Anxiety Inventory was applied preoperatively. Postoperative pain (presence and intensity) was recorded at 24, 48 and 72 h. The number of visits was not associated with postoperative pain (p = 0.806); pain intensity was highest at 24 h in both groups (p < 0.001). Moderate anxiety was significantly associated (p < 0.05) with pain in single- and multiple-visit. A genetic association was observed between the COMT rs174675 polymorphism and the outcome (p = 0.018), with greater pain reported by individuals with the CT genotype. (#RBR-47ngbg3).","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring Muscle Balance: A Self-Controlled Prospective Observational Study. 根管治疗在缓解根管疼痛引起的不对称和恢复肌肉平衡中的作用：一项自我控制的前瞻性观察研究。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2025-07-29 DOI: 10.1111/aej.12979

Kübra Gürler, İmran Güner Akgül, Hazal Duyan Yüksel, Selen Nihal Sisli

{"title":"The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring Muscle Balance: A Self-Controlled Prospective Observational Study.","authors":"Kübra Gürler, İmran Güner Akgül, Hazal Duyan Yüksel, Selen Nihal Sisli","doi":"10.1111/aej.12979","DOIUrl":"https://doi.org/10.1111/aej.12979","url":null,"abstract":"This study aimed to investigate whether root canal treatment (RCT) restores muscle symmetry by measuring the thickness of masseter and anterior temporalis muscles using ultrasonography. A self-controlled prospective observational study was conducted with patients experiencing moderate-to-severe endodontic pain and masticatory laterality. Ultrasonographic measurements of masseter and anterior temporalis muscles were taken at rest and during contraction before RCT, 1 week after treatment and 3 months post-treatment. An asymmetry index was calculated to evaluate changes in muscle thickness over time. Significant increases in masseter muscle thickness were observed on the painful side, both at rest and during contraction, while the control side showed a significant increase only during contraction. No statistically significant changes were observed in anterior temporalis muscle thickness, although a similar trend was noted. The asymmetry indices decreased significantly over time, approaching zero by the third month. RCT effectively reduces muscle asymmetry caused by endodontic pain, restoring balanced masticatory function. Trial Registration: ClinicalTrials.gov identifier: NCT06853028.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of the iVac System Compared to Conventional Irrigation and Ultrasonic Activation in Reducing Microbial Biofilm, Lipopolysaccharides and Apical Extrusion. iVac系统在减少微生物生物膜、脂多糖和根尖挤压方面的效果与常规灌洗和超声活化的比较

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2025-07-28 DOI: 10.1111/aej.12973

Brenda P F A Gomes, Ana B S Lopes, Emelly Aveiro, Lidiane M Louzada, Ederaldo P Godoi-Junior, Pedro I G Fagundes, Esdras G Alves-Silva, Antônio A L Moura-Filho, Rodrigo Arruda-Vasconcelos, Juliana D Bronzato

{"title":"Effectiveness of the iVac System Compared to Conventional Irrigation and Ultrasonic Activation in Reducing Microbial Biofilm, Lipopolysaccharides and Apical Extrusion.","authors":"Brenda P F A Gomes, Ana B S Lopes, Emelly Aveiro, Lidiane M Louzada, Ederaldo P Godoi-Junior, Pedro I G Fagundes, Esdras G Alves-Silva, Antônio A L Moura-Filho, Rodrigo Arruda-Vasconcelos, Juliana D Bronzato","doi":"10.1111/aej.12973","DOIUrl":"https://doi.org/10.1111/aej.12973","url":null,"abstract":"This in vitro study evaluated the effectiveness of irrigation techniques (IT)-conventional irrigation (CI), ultrasonic activation (UA), and iVac system (IA)- using 2.5% NaOCl and saline in reducing Enterococcus faecalis, Escherichia coli and Candida albicans in root canals and intratubular dentine. It also assessed the reduction of lipopolysaccharides (LPS) and apical extrusion. Lower premolar roots were contaminated and divided based on IT and irrigants, with saline as control. Microbiological and LPS samples were collected before and after IT. The apical extrusion volume was determined. Results showed that when NaOCl was used, there was no statistical difference between the ITs regarding CFU reduction and between UA and IA regarding LPS reduction. When saline was used, IA was the most effective technique in reducing CFU and LPS. Regarding apical extrusion, IA caused the lowest irrigant extrusion. In conclusion, IA reduced the levels of LPS, microorganisms and apical extrusion.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Post-Endodontic Pain Reduction Using Intracanal Cryotherapy in Symptomatic Apical Periodontitis. 治疗症状性根尖牙周炎采用管内冷冻治疗减轻根管后疼痛的疗效评价。

IF 1.3 4区医学

Australian Endodontic Journal Pub Date : 2025-07-25 DOI: 10.1111/aej.12983

Anam Fayyaz Bashir, Ussamah Waheed Jatala, Muhammad Amber Fareed, Sheryar Sheryar, Saadia Ahmad Chattha, Saima Razaq Khan, Shahzad Ahmad, Shazia Iqbal, Muhammad Sohail Zafar, Shahzad Ali

引用次数: 0

Stress in Immature Incisor Treated With Regenerative Endodontics or Restored With Bulk-Fill Resin Composite: A 2D Finite Element Analysis. 再生牙髓治疗或填充树脂复合材料修复未成熟门牙的应力：二维有限元分析。

IF 1.3 4区医学

Australian Endodontic Journal Pub Date : 2025-07-21 DOI: 10.1111/aej.12981

Gabriela Leite de Souza, Gabriel Felipe de Bragança, Andomar Bruno Fernandes Vilela, Airin Karelys Avendaño Rondón, Bill Kahler, Carlos José Soares, Camilla Christian Gomes Moura

{"title":"Stress in Immature Incisor Treated With Regenerative Endodontics or Restored With Bulk-Fill Resin Composite: A 2D Finite Element Analysis.","authors":"Gabriela Leite de Souza, Gabriel Felipe de Bragança, Andomar Bruno Fernandes Vilela, Airin Karelys Avendaño Rondón, Bill Kahler, Carlos José Soares, Camilla Christian Gomes Moura","doi":"10.1111/aej.12981","DOIUrl":"https://doi.org/10.1111/aej.12981","url":null,"abstract":"This study investigated the stress distribution on teeth undergoing regenerative endodontic treatment (RET) using two-dimensional finite element analysis (2D FEA). Five 2D-FEA models of immature incisors were developed, involving immediately after RET, models after RET varying root length and thickness: 10% increase in root length and root thickness; 10% increase in root length and 20% increase in root dentin thickness; 10% increase in root length and 40% increase in root dentin thickness; and a model after MTA apexification reinforced with resin composite. A biting load of 100 N was applied, and modified von Mises stress was analysed. Increasing root dentin thickness after RET provides limited benefit in the stress distribution, mainly by reducing the stress-to-area ratio in dentin. MTA apexification followed by resin composite restoration decreased intraradicular stress at the cervical region compared to RET. The combination of root dentin formation followed by filling with bulk-fill resin composite reduced root dentin stress.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are Extracellular Vesicles Used in Tissue Engineering Effective for Regenerative Endodontic Treatments? Scoping Review. 组织工程中使用细胞外囊泡对再生牙髓治疗有效吗？确定审核范围。

IF 1.3 4区医学

Australian Endodontic Journal Pub Date : 2025-07-18 DOI: 10.1111/aej.12980

Carolina Dos Santos Santinoni, Jéssica Pestana, Lívia Apolito Rissi, Milena de Queiroz Guedes, Graziela Garrido Mori Panucci

{"title":"Are Extracellular Vesicles Used in Tissue Engineering Effective for Regenerative Endodontic Treatments? Scoping Review.","authors":"Carolina Dos Santos Santinoni, Jéssica Pestana, Lívia Apolito Rissi, Milena de Queiroz Guedes, Graziela Garrido Mori Panucci","doi":"10.1111/aej.12980","DOIUrl":"https://doi.org/10.1111/aej.12980","url":null,"abstract":"The purpose was to analyse the efficacy of extracellular vesicles (EVs) used in tissue engineering for regenerative endodontic treatments. The study followed the Guidance's recommendations for conducting systematic scoping reviews. A systematic electronic search was conducted to answer: \"Are extracellular vesicles used in tissue engineering effective for regenerative endodontic treatments?\". A total of 393 scientific articles were selected, and after applying the inclusion criteria and excluding duplicate articles, 14 articles were included in this research. The most used EVs were exosomes, which were mostly extracted from stem cells and used in association with biomaterials or cells. All included studies demonstrated the effectiveness of extracellular vesicles in promoting pulp regeneration. The mechanisms involved in tissue formation include odontogenic and angiogenic differentiation, as well as control of the inflammatory process after the use of EVs. It is concluded that therapy with EVs is promising for endodontic clinics.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Inflammatory Response in Periodontal Tissues After Walking Bleach: A Clinical Biomarker-Based Study. 行走漂白剂后牙周组织持续炎症反应：一项基于临床生物标志物的研究。

IF 1.3 4区医学

Australian Endodontic Journal Pub Date : 2025-07-16 DOI: 10.1111/aej.12975

Cristian Bersezio Miranda, Carla Mayer, Paulina Ledezma, Rolando Vernal, Oriana Rivera, Eduardo Fernández Godoy

{"title":"Persistent Inflammatory Response in Periodontal Tissues After Walking Bleach: A Clinical Biomarker-Based Study.","authors":"Cristian Bersezio Miranda, Carla Mayer, Paulina Ledezma, Rolando Vernal, Oriana Rivera, Eduardo Fernández Godoy","doi":"10.1111/aej.12975","DOIUrl":"https://doi.org/10.1111/aej.12975","url":null,"abstract":"This study evaluated the long-term inflammatory response in periodontal tissues following intra-coronal bleaching of non-vital anterior teeth using two peroxide-based agents. Fifty participants were randomised to receive either 35% hydrogen peroxide or 37% carbamide peroxide via the walking bleach technique. Gingival crevicular fluid was collected at five time points over 12 months, and inflammatory biomarkers were analysed. Both bleaching protocols resulted in significant and sustained increases in interleukin-1 beta and receptor activator of nuclear factor kappa-B ligand concentrations, without significant differences between agents. Tooth whitening was effective and stable over time. The strong correlation between both biomarkers suggests a persistent low-grade inflammatory state induced by bleaching. These findings highlight the biological impact of intra-coronal bleaching on periodontal tissues, even in the absence of clinical symptoms, and underscore the need for individualised risk assessment when planning aesthetic treatment in endodontically treated teeth. Trial Registration: ClinicalTrials.gov identifier: NCT02718183.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Clinical Outcomes of Two Hydraulic Calcium Silicate Cements for Pulpotomy in Cariously Exposed Permanent Teeth-A Systematic Review. 两种水合硅酸钙骨水泥用于牙髓切开术的临床效果比较——系统评价。

IF 1.3 4区医学

Australian Endodontic Journal Pub Date : 2025-07-16 DOI: 10.1111/aej.12968

William Holme, Flavio Pisani, Khaled Altamimi, Shalini Kanagasingam

{"title":"Comparison of Clinical Outcomes of Two Hydraulic Calcium Silicate Cements for Pulpotomy in Cariously Exposed Permanent Teeth-A Systematic Review.","authors":"William Holme, Flavio Pisani, Khaled Altamimi, Shalini Kanagasingam","doi":"10.1111/aej.12968","DOIUrl":"https://doi.org/10.1111/aej.12968","url":null,"abstract":"This systematic review analysed clinical studies to determine if Biodentine offers improved outcomes for pulpotomy in cariously exposed permanent teeth compared to MTA, supporting its potential recommendation. A systematic search of MEDLINE, Oral and Dental Sciences Source, and EMBASE was conducted. Inclusion and exclusion criteria identified clinical studies comparing MTA and Biodentine for pulpotomy. The outcome measured was 'overall success,' based on clinical and radiographic evaluations. Two independent reviewers performed data extraction and quality assessment using the Risk of Bias 2 tool. Four randomised controlled trials with 265 teeth and follow-up up to 6 years met the inclusion criteria. One study had a high risk of bias, whereas only one study was deemed to have a low risk of bias. No statistically significant differences were found between Biodentine and MTA. Based on our findings, Biodentine is a viable alternative to MTA, showing similar outcomes. Further long-term clinical studies are needed to determine optimal biomaterials to improve clinical outcomes.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Cavity Design on Bacterial Reduction in Root Canals and Postoperative Pain Level: A Randomised Controlled Trial. 空腔设计对根管细菌减少和术后疼痛水平的影响：一项随机对照试验。

IF 1.3 4区医学

Australian Endodontic Journal Pub Date : 2025-07-10 DOI: 10.1111/aej.12976

M M Özen, E Karataş

引用次数: 0