Australian Endodontic Journal最新文献_第2页

Impact of EDTA Formulations and Activation Methods on Stem Cell Response, Antimicrobial Activity and Dentine Integrity: An In Vitro Study. EDTA配方和激活方法对干细胞反应、抗菌活性和牙本质完整性的影响：一项体外研究

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-08 DOI: 10.1111/aej.70076

Letycia Accioly Simões Coelho, Laura Ferreira Almeida, Ester Alves Ferreira Bordini, Fernanda Balestrero Cassiano, Mirela Cesar Barros, Talita Tartari, Flaviana Bombarda de Andrade, Diana Gabriela Soares Dos Passos, Marco Antonio Hungaro Duarte

{"title":"Impact of EDTA Formulations and Activation Methods on Stem Cell Response, Antimicrobial Activity and Dentine Integrity: An In Vitro Study.","authors":"Letycia Accioly Simões Coelho, Laura Ferreira Almeida, Ester Alves Ferreira Bordini, Fernanda Balestrero Cassiano, Mirela Cesar Barros, Talita Tartari, Flaviana Bombarda de Andrade, Diana Gabriela Soares Dos Passos, Marco Antonio Hungaro Duarte","doi":"10.1111/aej.70076","DOIUrl":"https://doi.org/10.1111/aej.70076","url":null,"abstract":"This study evaluated the effects of 17% trisodium EDTA and 15% disodium EDTA (EDTAd), with or without activation, on SCAP response, antimicrobial activity and dentine chemical alterations. SCAP viability (Live/Dead) and metabolic activity (Alamar Blue) were assessed, along with antibiofilm and intratubular disinfection against Enterococcus faecalis and Streptococcus mutans, after irrigation with EDTA or EDTAd delivered by conventional irrigation (CI), ultrasonic activation (UA) or diode laser activation (LA). Dentine alterations were analysed by Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). EDTA preserved higher SCAP metabolic activity, particularly at early time points (p < 0.05), while cytotoxicity did not differ among groups. Antibiofilm and intratubular antimicrobial effects were similar across irrigants and activation methods (p > 0.05). EDTAd caused greater alterations in the amide III/phosphate ratio (p < 0.05), with increased smear-layer removal and surface irregularities. EDTA showed greater biological compatibility and fewer dentine alterations, whereas EDTAd induced more pronounced structural changes without antimicrobial differences.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and Future Perspectives in Additive Modifications of Calcium Silicate-Based Cements: A Scoping Review (2015-2024). 硅酸盐钙基水泥添加剂改性的趋势和未来展望：范围综述（2015-2024）。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-07 DOI: 10.1111/aej.70077

Kenta Tsuchiya, Salvatore Sauro, Jukka P Matinlinna, Monica Yamauti, Hidehiko Sano, Kyung-San Min, Atsushi Tomokiyo

{"title":"Trends and Future Perspectives in Additive Modifications of Calcium Silicate-Based Cements: A Scoping Review (2015-2024).","authors":"Kenta Tsuchiya, Salvatore Sauro, Jukka P Matinlinna, Monica Yamauti, Hidehiko Sano, Kyung-San Min, Atsushi Tomokiyo","doi":"10.1111/aej.70077","DOIUrl":"10.1111/aej.70077","url":null,"abstract":"This scoping review identified commonly modified commercial calcium silicate-based cements (CSCs), evaluate additive-property trends and highlight research gaps relevant to their clinical application. Laboratory studies published between 2015 and 2024 were searched in PubMed, ScienceDirect and Web of Science following PRISMA-ScR. Fifty-one studies met the inclusion criteria, with ProRoot being the most frequently studied CSC. Additive modifications primarily targeted setting time, biocompatibility, antibacterial property and osteogenic differentiation. A recent shift from bioactivity-focused to physicochemical optimization was observed. Heat map analysis demonstrated distinct additive category-property associations, with metals and fluorides mainly linked to antibacterial enhancement, phosphate-based and bioactive compounds to biocompatibility and osteogenic outcomes, and commonly used setting modifiers, including calcium chloride, associated with accelerated setting. These findings indicate that single-category additive strategies are insufficient and that several CSC properties remain underexplored, supporting the need for more integrative CSC design.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Well Are Dental Students Equipped to Handle Traumatic Dental Injuries in Children? 牙科专业的学生如何处理儿童创伤性牙齿损伤？

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-06 DOI: 10.1111/aej.70074

Sobia Zafar, Luan Lin Jovita Cheong, Vonn Ler, Anastasia Min Teh, Paul Abbott

引用次数: 0

Comparative In Vitro Evaluation of Antibacterial Activity of Ganoderma lucidum– and Psidium guajava–Loaded Drug Delivery Scaffolds Against Enterococcus faecalis Biofilms 灵芝和番石榴载药支架对粪肠球菌生物膜抑菌活性的体外比较研究

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-10-23 DOI: 10.1111/aej.70026

Sheetal Ghivari, Meena Naganath, Girish Kubasad, Manohar S. Kugaji, Ulka Idate

{"title":"Comparative In Vitro Evaluation of Antibacterial Activity of Ganoderma lucidum– and Psidium guajava–Loaded Drug Delivery Scaffolds Against Enterococcus faecalis Biofilms","authors":"Sheetal Ghivari, Meena Naganath, Girish Kubasad, Manohar S. Kugaji, Ulka Idate","doi":"10.1111/aej.70026","DOIUrl":"10.1111/aej.70026","url":null,"abstract":"<div>\u0000 \u0000 This in vitro study evaluated the antibacterial efficacy of novel herbal intracanal medicaments, specifically Ganoderma lucidum (GL) and Psidium guajava (PG) extracts, incorporated into Pluronic F127 drug delivery scaffolds, against Enterococcus faecalis biofilms. Biofilms were established on standardised dentine specimens and treated with herbal-loaded hydrogels, calcium hydroxide (CH), modified triple antibiotic paste (mTAP) or saline (control). Antibacterial activity was assessed via colony-forming unit (CFU) counts, quantitative real-time PCR (qPCR), and confocal laser scanning microscopy (CLSM). Results revealed significant antibacterial effects in all medicated groups compared to control, with mTAP exhibiting the highest efficacy, followed by CH and PG. PG's performance was comparable to CH and superior to GL. The study supports the potential of PG and GL herbal-loaded scaffolds as alternative intracanal medicaments pending further in vivo research.\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"9-16"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145356904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Intracanal Medicaments on Cell Cycle, Viability and Differentiation of Human Apical Papilla Mesenchymal Stem Cells (hAP-MSCs) 肛管内药物对人根尖乳头间充质干细胞（hAP-MSCs）细胞周期、活力和分化的影响

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-11-10 DOI: 10.1111/aej.70033

Morankar Rahul, Pankaj Keshari, Riyaz Ahmed Mir, Nitesh Tewari, Vijay Mathur, Jhunjhunwala Garima, Kalpana Bansal, Rahul Yadav

{"title":"Impact of Intracanal Medicaments on Cell Cycle, Viability and Differentiation of Human Apical Papilla Mesenchymal Stem Cells (hAP-MSCs)","authors":"Morankar Rahul, Pankaj Keshari, Riyaz Ahmed Mir, Nitesh Tewari, Vijay Mathur, Jhunjhunwala Garima, Kalpana Bansal, Rahul Yadav","doi":"10.1111/aej.70033","DOIUrl":"10.1111/aej.70033","url":null,"abstract":"<div>\u0000 \u0000 This in vitro experiment evaluated cell cycle, viability and osteogenic differentiation of human apical papilla-derived mesenchymal stem cells (hAP-MSCs) by intracanal medicaments used in regenerative endodontic treatment. Apical papilla tissues of immature extracted tooth roots were digested, trypsinized and resuspended as a single cell suspension stained with CD146, CD73 and CD90 antibodies. Results revealed that apical papilla tissue harbours hAP-MSCs, and they can be cultured and characterised. Low-concentration intracanal medicaments (0.025 mg/mL) were less cytotoxic compared to higher concentrations (0.1 mg/mL and above). Calcium hydroxide was better in terms of viability as well as osteogenic differentiation (at 0.025, 0.05 and 0.1 mg/mL concentration) than triple antibiotic paste (TAP), modified TAP, and DAP (double antibiotic paste) at 24, 48, and 72 h. Thus, calcium hydroxide was less cytotoxic compared to the different antibiotic paste combinations.\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"110-123"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145490419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellular and Mechanical Responses to Zinc Polycarboxylate Cement Modified With 5% or 10% Potassium Nitrate: An In Vitro Study 5%或10%硝酸钾改性聚羧酸锌水泥的细胞和力学反应：体外研究。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-09-25 DOI: 10.1111/aej.70022

Fatimah Dahlawi, Mohammed AlGharni, Marwa Madi, Neveen M. Ayad, Faisal Alonizan, Nada Aldossary, Omar Omar

{"title":"Cellular and Mechanical Responses to Zinc Polycarboxylate Cement Modified With 5% or 10% Potassium Nitrate: An In Vitro Study","authors":"Fatimah Dahlawi, Mohammed AlGharni, Marwa Madi, Neveen M. Ayad, Faisal Alonizan, Nada Aldossary, Omar Omar","doi":"10.1111/aej.70022","DOIUrl":"10.1111/aej.70022","url":null,"abstract":"<div>\u0000 \u0000 This study investigated the biological response of human peripheral blood mononuclear cells (PBMCs) to zinc polycarboxylate (ZP) cement modified with 5% or 10% potassium nitrate (KNO3) and assessed its mechanical properties. Discs of unmodified ZP, ZP + 5% KNO3, ZP + 10% KNO3, or mineral trioxide aggregate (MTA) were indirectly exposed to PBMCs using a transwell system. Cells were incubated with or without lipopolysaccharide (LPS) stimulation. Cytotoxicity (LDH release), viability, IL-6 and TGF-β secretion were evaluated. Material pH, ion release, compressive strength and microhardness were also assessed. ZP + 5% KNO3 significantly reduced LDH and IL-6 levels and increased TGF-β release compared to ZP alone. Mechanical strength was maintained in ZP + 5% KNO3 but decreased at 10% KNO3. MTA showed lower strength but higher cell viability. ZP + 5% KNO3 demonstrated a balanced profile of immunomodulation, regenerative signalling and mechanical integrity, supporting its potential use in vital pulp therapy. Further in vivo investigations are recommended.\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"59-69"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Supplementary Irrigation Methods Against Bacterial Biofilm-Infected Root Canals Prepared With Minimally Invasive and Conventional Techniques 辅助灌洗方法对微创与常规根管制备的细菌生物膜感染的疗效观察。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-10-07 DOI: 10.1111/aej.70024

Giuliana Soimu, Abhishek Parolia, Anelise V. Masiero, Fang Qian, Thomas Moninger, Jeffrey A. Banas, Fabricio B. Teixeira

{"title":"Efficacy of Supplementary Irrigation Methods Against Bacterial Biofilm-Infected Root Canals Prepared With Minimally Invasive and Conventional Techniques","authors":"Giuliana Soimu, Abhishek Parolia, Anelise V. Masiero, Fang Qian, Thomas Moninger, Jeffrey A. Banas, Fabricio B. Teixeira","doi":"10.1111/aej.70024","DOIUrl":"10.1111/aej.70024","url":null,"abstract":"<div>\u0000 \u0000 This study evaluated the effectiveness of the GentleWave system (GWS), laser-activated irrigation (LAI), ultrasonic-activated irrigation (UAI) and sonic irrigation (SI) in removing a three-species biofilm from infected root canals prepared using minimally invasive techniques (MIT) and conventional instrumentation techniques (CIT). One hundred and ten single-canalled mandibular premolars were infected with the biofilm and assigned to five groups based on the supplementary irrigation method used. Biofilm removal was assessed using confocal laser scanning microscopy and scanning electron microscopy. In the CIT group, GWS resulted in a significantly higher proportion of dead cells compared to UAI and SI (p < 0.05), with no significant difference between GWS and LAI. In the MIT group, no significant differences were observed among the irrigation methods (p > 0.05). Although none of the approaches completely eliminated the biofilm, GWS and LAI were more effective than UAI and SI.\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"46-58"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast 牙髓螯合剂依地膦酸钠对牙周韧带成纤维细胞的细胞毒性研究。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-10-29 DOI: 10.1111/aej.70029

Bruno Vila Nova de Almeida, Patrícia de Almeida Rodrigues, Geovanni Pereira Mitre, Maria Sueli da Silva Kataoka, João de Jesus Viana Pinheiro, Talita Tartari, Oscar Faciola Pessoa

{"title":"Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast","authors":"Bruno Vila Nova de Almeida, Patrícia de Almeida Rodrigues, Geovanni Pereira Mitre, Maria Sueli da Silva Kataoka, João de Jesus Viana Pinheiro, Talita Tartari, Oscar Faciola Pessoa","doi":"10.1111/aej.70029","DOIUrl":"10.1111/aej.70029","url":null,"abstract":"Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was characterised by immunofluorescence and real-time quantitative polymerase chain reaction. The half-maximal inhibitory concentration (IC50) was tested: 9% HEBP, 18% HEBP, 24% HEBP, 15% EDTA, 17% EDTA, 24% EDTA, and control. Exposure times were 1, 4, and 24 h. The Kruskal-Wallis test, followed by Dunn's post hoc, assessed multiple comparisons between the groups (α = 0.05). All experimental groups showed a lower IC50 effect after 24 h, except 9% HEBP. EDTA cytotoxicity depends on the contact time, regardless of the concentration. In conclusion, 9% HEBP is a biocompatible alternative to EDTA as an endodontic chelator, particularly for protocols requiring longer exposure times.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"84-91"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Solubility, pH, Antimicrobial Action and Cytotoxicity of Calcium Hydroxide Paste Associated With Ambroxol Hydrochloride 盐酸氨溴索与氢氧化钙膏体的溶解度、pH、抗菌作用及细胞毒性分析。

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-11-22 DOI: 10.1111/aej.70039

Thaís Ferreira Rodrigues Mota, Ana Flávia Balestrero Cassiano, Pedro César Gomes Titato, Pedro Henrique Souza Calefi, Murilo Priori Alcalde, Gisele Faria, Marco Antonio Hungaro Duarte

{"title":"Analysis of Solubility, pH, Antimicrobial Action and Cytotoxicity of Calcium Hydroxide Paste Associated With Ambroxol Hydrochloride","authors":"Thaís Ferreira Rodrigues Mota, Ana Flávia Balestrero Cassiano, Pedro César Gomes Titato, Pedro Henrique Souza Calefi, Murilo Priori Alcalde, Gisele Faria, Marco Antonio Hungaro Duarte","doi":"10.1111/aej.70039","DOIUrl":"10.1111/aej.70039","url":null,"abstract":"This study evaluated the association of ambroxol hydrochloride with calcium hydroxide paste as intracanal medication to enhance antimicrobial action on biofilm without affecting pH, solubility and cytotoxicity. Calcium hydroxide (CH) paste and formulations with different ambroxol concentrations were placed into artificial teeth conditioned in distilled water. pH and solubility were measured. Dentine discs infected with E. faecalis were covered with pastes, and biofilm viability was analysed using live/dead assay and confocal microscope. Cytotoxicity was analysed using MTT assay on fibroblast and osteoblast-like cells. Data were statistically compared (p < 0.05). Ambroxol showed an acidic pH after 7 days, compared to CH, but the 30% concentration became more alkaline after 30 days. While CH's pH decreased over time, ambroxol groups maintained stability. Solubility decreased for all groups over time. All groups showed significant antimicrobial differences from the control group. The association did not alter CH's cytotoxicity. Further research is needed for optimal ambroxol concentration.","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"148-155"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

YouTube and Root Canal Irrigation Activation: Are We Learning Quality Content? YouTube和根管灌溉激活：我们正在学习高质量的内容吗？

IF 1.5 4区医学

Australian Endodontic Journal Pub Date : 2026-04-05 Epub Date: 2025-11-25 DOI: 10.1111/aej.70041

Yagmur Kilic, Samet Tosun, Emrah Karataslioglu

{"title":"YouTube and Root Canal Irrigation Activation: Are We Learning Quality Content?","authors":"Yagmur Kilic, Samet Tosun, Emrah Karataslioglu","doi":"10.1111/aej.70041","DOIUrl":"10.1111/aej.70041","url":null,"abstract":"<div>\u0000 \u0000 This study aimed to evaluate the quality, reliability, and educational value of YouTube videos related to irrigation activation in endodontics. A total of 70 videos were analyzedusing the keyword ‘irrigation activation methods’. Videos were assessed using JAMA, DISCERN and GQS. Additional popularity metrics were recorded. Statistical analyses were performed using the Kruskal–Wallis and Spearman correlation tests (p < 0.05). The majority of videos demonstrated low content quality (68.6%, GQS ≤ 2) and weak accuracy (47%, JAMA ≤ 1). Longer videos were associated with higher quality scores, while popularity metrics did not show significant correlations with educational quality. A weak but statistically significant correlation was found between DISCERN and II (r = 0.261, p = 0.029). Positive correlations among JAMA, DISCERN, and GQS confirmed the consistency of these scales. Overall, the findings indicate that the quality of YouTube videos on irrigation activation varies considerably. While video length may enhance content quality by allowing for more comprehensive explanations, popularity indicators are not reliable measures of educational accuracy.\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 1","pages":"124-129"},"PeriodicalIF":1.5,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0