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In Vitro Antimicrobial Efficacy of Irrigants With Ni-Ti Instruments on Mixed Biofilm in Premolar Root Canals With Conservative Access Cavity. 镍钛器械冲洗剂对前磨牙根管保守通道混合生物膜的体外抗菌效果研究。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-05-03 DOI: 10.1111/aej.12947
Yun Huang, Rui Xu, Ying Lv, Jiadi Shen, Xin Wei
{"title":"In Vitro Antimicrobial Efficacy of Irrigants With Ni-Ti Instruments on Mixed Biofilm in Premolar Root Canals With Conservative Access Cavity.","authors":"Yun Huang, Rui Xu, Ying Lv, Jiadi Shen, Xin Wei","doi":"10.1111/aej.12947","DOIUrl":"https://doi.org/10.1111/aej.12947","url":null,"abstract":"<p><p>Conservative access cavity (ConsAC) has been increasingly advocated to preserve tooth structure, but its effect on disinfection efficacy against complex biofilms remains unclear. This study evaluated the effectiveness of different irrigants combined with Ni-Ti instruments on mixed biofilms of Enterococcus faecalis and Candida albicans in maxillary premolars with ConsAC or traditional access cavity (TradAC). A total of 208 extracted intact premolars were divided into ConsAC and TradAC groups. Root canals were infected with mixed biofilms and treated with 2.5% NaOCl, 2% CHX or 1% farnesol, followed by preparation using ProTaper Gold (PTG) or XP-endo Shaper (XPS). Efficacy was assessed using CFU counting, SEM, and CLSM. PTG was more effective than XPS under the same conditions. NaOCl showed superior antimicrobial activity compared with CHX and farnesol. TradAC achieved better microbial reduction than ConsAC. This study provides evidence-based insights into the disinfection performance of different irrigation-instrument combinations under varying access designs.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Farewell Editorial 告别编辑
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-04-14 DOI: 10.1111/aej.12935
Stephen C. Harlamb
{"title":"Farewell Editorial","authors":"Stephen C. Harlamb","doi":"10.1111/aej.12935","DOIUrl":"https://doi.org/10.1111/aej.12935","url":null,"abstract":"","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"1"},"PeriodicalIF":1.3,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Success Rate of Single Versus Two-Visit Regenerative Treatment Protocol in Non-Vital Mature Anterior Teeth (A Preliminary Randomised Clinical Trial). 非生命成熟前牙单次与二次再生治疗方案的成功率（初步随机临床试验）。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-04-11 DOI: 10.1111/aej.12943
Lamiaa Ragaei Lasheen, Shaimaa Ismail Gawdat, Reem Ahmed Lutfy
{"title":"Success Rate of Single Versus Two-Visit Regenerative Treatment Protocol in Non-Vital Mature Anterior Teeth (A Preliminary Randomised Clinical Trial).","authors":"Lamiaa Ragaei Lasheen, Shaimaa Ismail Gawdat, Reem Ahmed Lutfy","doi":"10.1111/aej.12943","DOIUrl":"https://doi.org/10.1111/aej.12943","url":null,"abstract":"<p><p>This study compared the success rate following single-visit versus two-visit regenerative endodontic procedures of non-vital mature anterior teeth with periapical lesion. Thirty-two patients were randomly assigned into two groups: group A: single visit and group B: two visit. All assigned teeth were chemo-mechanically prepared. For group A, platelet rich fibrin was placed into the root canal followed by the placement of Biodentine and final restoration. For group B, calcium hydroxide was placed for 3 weeks, followed by the same regenerative procedures in the second visit. Follow-up visits were at 3, 6, 9 and 12 months, and periapical lesion was assessed by CBCT at the beginning and 12 months after treatment. There was no statistical difference between the success rate of group A (28.6%) and group B (64.3%). Regenerative endodontic procedure can be a promising treatment for mature non-vital teeth with further investigations needed for the single-visit protocol. Trial Registration: Registered at www.clinicaltrials.com NCT03717337.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management Options and Outcomes for Root-Filled Teeth That Have a Periapical Radiolucency 根尖周放射率高的补根牙的治疗选择和结果。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-28 DOI: 10.1111/aej.12917
Jordan Samuel Blum
{"title":"Management Options and Outcomes for Root-Filled Teeth That Have a Periapical Radiolucency","authors":"Jordan Samuel Blum","doi":"10.1111/aej.12917","DOIUrl":"10.1111/aej.12917","url":null,"abstract":"<p>Post-treatment endodontic disease (PTED) may be defined by the presence of a periapical radiolucency in a previously root-filled tooth when the lesion can no longer be assumed to be healing. When a diagnosis of PTED is made, theoretically only three management options remain: no treatment (review and reassess), endodontic retreatment (nonsurgical or surgical), or extraction (including root resection). The purpose of this paper is to provide clinicians with a current and clinically relevant summary of the management options for PTED, with an emphasis on aetiology, case selection, and related outcomes to help clinicians filter and provide management options to the patient.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"10-16"},"PeriodicalIF":1.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/aej.12917","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Treatment Apical Periodontitis: Endodontic Infection Contributes to Circulating Microbial DNA. 根尖牙周炎治疗后：根管感染有助于循环微生物DNA。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-27 DOI: 10.1111/aej.12942
Yanglin Zeng, Liu Wang, Mudan Wang, Liu Liu, Yao Song, Dongzhe Song, Dingming Huang
{"title":"Post-Treatment Apical Periodontitis: Endodontic Infection Contributes to Circulating Microbial DNA.","authors":"Yanglin Zeng, Liu Wang, Mudan Wang, Liu Liu, Yao Song, Dongzhe Song, Dingming Huang","doi":"10.1111/aej.12942","DOIUrl":"https://doi.org/10.1111/aej.12942","url":null,"abstract":"<p><p>This study investigated the impact of post-treatment apical periodontitis on microbial DNA in patients' blood circulation. Samples from the root apex, periapical lesion and peripheral blood of 11 patients, along with peripheral blood from nine healthy controls, were analysed using next-generation sequencing. The microbial DNA composition, diversity and linear discriminant analysis effect size were analysed. The SourceTracker was applied to trace microorganisms of peripheral blood. Proteobacteria dominated peripheral blood and periapical lesions, while Actinobacteria prevailed in the root apex. Patients exhibited higher microbial diversity in blood but reduced α-diversity in the root apex compared to other sites. Moreover, Bacteroides, as well as Aliihoeflea, Oceanicaulis, Comamonas, Shigella and Acinetobacter, showed increased relative abundance in the blood of patients. Additionally, the root apex contributed 26% and the periapical lesion contributed 76% to peripheral blood for the bacteria. These findings suggested unique microbial translocation in post-treatment apical periodontitis patients.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of 2-Hydroxyisocaproic Acid on Growth Factor Release From Dentin in Regenerative Endodontic Treatments. A Laboratory Study. 2-羟基异己酸对再生牙本质中生长因子释放的影响。实验室研究。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-26 DOI: 10.1111/aej.12941
Sıla Nur Usta, Emre Avcı, Eda Doğuş, Maria Teresa Arias-Moliz
{"title":"Influence of 2-Hydroxyisocaproic Acid on Growth Factor Release From Dentin in Regenerative Endodontic Treatments. A Laboratory Study.","authors":"Sıla Nur Usta, Emre Avcı, Eda Doğuş, Maria Teresa Arias-Moliz","doi":"10.1111/aej.12941","DOIUrl":"https://doi.org/10.1111/aej.12941","url":null,"abstract":"<p><p>This study aimed to assess the effect of 2-hydroxyisocaproic acid (HICA) on the TGF-β1, IGF-1, BMP-7, and VEGF-A release from root canal dentin, compared to calcium hydroxide (CH) and double antibiotic paste (DAP) in regenerative endodontic treatments (RET). Forty-eight single-canal teeth were prepared to mimic immature teeth and treated according to the RET protocol. Teeth were divided into three experimental (HICA, CH, and DAP) and one control (non-dressed) group. TGF-β1, BMP-7, IGF-1 and VEGF-A levels were measured using an ELISA kit on days 1 and 7. Significantly higher TGF-β1 release was found in the HICA and CH groups than in the other groups (p < 0.05). While the levels of growth factor release were notably higher on day 7 in the HICA group (p < 0.05), the values remained consistent across both time intervals within the control group. HICA proved to be effective as an intracanal medicament in enhancing the release of growth factors.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Material Composition and Surface Finish on the Bending Strength of Ultrasonic Irrigant Activation Tips. 材料成分和表面光洁度对超声灌溉激活头抗弯强度的影响。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-25 DOI: 10.1111/aej.12940
Emmanuel J N L Silva, Jorge N R Martins, Victor T L Vieira, Abayomi Omokeji Baruwa, Gustavo De-Deus, Marco A Versiani
{"title":"Impact of Material Composition and Surface Finish on the Bending Strength of Ultrasonic Irrigant Activation Tips.","authors":"Emmanuel J N L Silva, Jorge N R Martins, Victor T L Vieira, Abayomi Omokeji Baruwa, Gustavo De-Deus, Marco A Versiani","doi":"10.1111/aej.12940","DOIUrl":"https://doi.org/10.1111/aej.12940","url":null,"abstract":"<p><p>This study evaluated the design, surface finish, alloy composition, and bending strength of three ultrasonic tips-Ultra X Silver, Gold, and Blue-used for irrigant activation. Using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and bending strength tests, 30 ultrasonic tips were analysed. SEM revealed a flat, non-active tip design for all tips, with Ultra X Silver having the smoothest surface and Ultra X Gold the most irregular. EDS showed that Ultra X Silver was made of a titanium-aluminium alloy, while Ultra X Gold and Ultra X Blue were stainless steel. In bending strength tests, Ultra X Silver demonstrated the highest flexibility (315.3 gf), while Ultra X Gold had the lowest (474.5 gf). Statistical analysis showed significant differences (p < 0.05) in flexibility, surface characteristics, and composition. Ultra X Silver's smoother surface and titanium alloy enhance flexibility, ideal for curved canals, whereas Ultra X Gold offers durability but less flexibility.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Laboratory Investigation of the Effectiveness of Different Acids in Removing Mineral Trioxide Aggregate From Simulated Root Canals. 不同酸对模拟根管中三氧化二矿骨料去除效果的实验室研究。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-24 DOI: 10.1111/aej.12937
Stephanie Chan, Paul V Abbott
{"title":"A Laboratory Investigation of the Effectiveness of Different Acids in Removing Mineral Trioxide Aggregate From Simulated Root Canals.","authors":"Stephanie Chan, Paul V Abbott","doi":"10.1111/aej.12937","DOIUrl":"https://doi.org/10.1111/aej.12937","url":null,"abstract":"<p><p>The aim was to compare the effectiveness of acids in removing MTA from root canals. Fifty acrylic blocks were filled with MTA and divided into groups - 10% hydrochloric acid; 10% citric acid; 2% acetic acid; 2% carbonic acid and 20% tartaric acid. MTA was removed with the acids, plus ultrasonic tips and rotary files. Outcomes were measured as pre- and post-operative weight differences, luminance differences and working time to regain length or form ledges. Weight differences varied significantly - citric acid was highest; hydrochloric acid was lowest and others were not statistically different from each other. Luminance did not differ significantly between groups but varied significantly with distance from the apex - hydrochloric acid and carbonic acid were lowest at 1 mm from the apex. Working times differed significantly - hydrochloric acid took longer than other acids except citric acid. Overall, the most effective acid was citric acid. The least effective was hydrochloric acid.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guided Endodontic Access Enhances the Management of Calcified Root Canals Regardless of Operator's Experience: A Scoping Review. 引导根管通道增强钙化根管的管理，而不考虑操作人员的经验：范围回顾。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-24 DOI: 10.1111/aej.12939
Lara B Deus, Maria Luiza L Santana, Patricia C Siqueira, Giampiero Rossi-Fedele, Orlando A Guedes, Julio A Silva, Daniel A Decurcio
{"title":"Guided Endodontic Access Enhances the Management of Calcified Root Canals Regardless of Operator's Experience: A Scoping Review.","authors":"Lara B Deus, Maria Luiza L Santana, Patricia C Siqueira, Giampiero Rossi-Fedele, Orlando A Guedes, Julio A Silva, Daniel A Decurcio","doi":"10.1111/aej.12939","DOIUrl":"https://doi.org/10.1111/aej.12939","url":null,"abstract":"<p><p>Performing conventional endodontic access in teeth with root canal obliteration presents significant challenges due to difficulties in locating and accessing the canals, often leading to unnecessary loss of dental structure and increased risk of perforations. Consequently, specialist referral is frequently recommended. Guided endodontics emerges as a promising alternative that facilitates access to calcified canals. This scoping review assesses the influence of the operator's experience on the accuracy and efficiency of guided endodontic access. A search across eight electronic databases until August 4, 2024, identified 999 records, from which 31 articles were analysed. These studies evaluated the association between operator experience and guided access outcomes. Despite variability in guide models and evaluated parameters, operators of different experience levels demonstrated similar performance. Thus, guided endodontics is a precise and efficient technique, beneficial even for less experienced operators. The primary limitations stem from the scarcity and methodological limitations of existing studies.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Premedication With Ketorolac on Anaesthetic Success of Mental-Incisive Nerve Blocks With Symptomatic Irreversible Pulpitis: Comment 预用药酮罗拉酸对对症不可逆性牙髓炎精神-切口神经阻滞麻醉成功的疗效评价。
IF 1.3 4区 医学
Australian Endodontic Journal Pub Date : 2025-03-19 DOI: 10.1111/aej.12931
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Efficacy of Premedication With Ketorolac on Anaesthetic Success of Mental-Incisive Nerve Blocks With Symptomatic Irreversible Pulpitis: Comment","authors":"Hinpetch Daungsupawong,&nbsp;Viroj Wiwanitkit","doi":"10.1111/aej.12931","DOIUrl":"10.1111/aej.12931","url":null,"abstract":"","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 1","pages":"235-236"},"PeriodicalIF":1.3,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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