Australian Endodontic Journal最新文献

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Irrigation Dynamics of the TruNatomy Needle in a Minimally Prepared Root Canal: A Computational Fluid Dynamics Analysis. 椎弓根管针在最小预备根管内的灌流动力学:计算流体动力学分析。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-09-14 DOI: 10.1111/aej.70120
Selventhra Savitha, Vijay Kumar, Sidhartha Sharma, Amrita Chawla, Ajay Logani
{"title":"Irrigation Dynamics of the TruNatomy Needle in a Minimally Prepared Root Canal: A Computational Fluid Dynamics Analysis.","authors":"Selventhra Savitha, Vijay Kumar, Sidhartha Sharma, Amrita Chawla, Ajay Logani","doi":"10.1111/aej.70120","DOIUrl":"https://doi.org/10.1111/aej.70120","url":null,"abstract":"<p><p>This study investigated the irrigation dynamics of the TruNatomy irrigation needle in a minimally shaped root canal using Computational Fluid Dynamics (CFD). The root canal geometry of an extracted maxillary first molar was reconstructed via micro-Computed Tomography (CT) scan, and the needle dimensions were obtained through stereomicroscopic analysis for Computer-Aided Design (CAD) modelling. The needle was virtually placed 1 mm short of the working length, and a prevalidated CFD model simulated the irrigation process. Irrigant penetration was confined to the needle tip, with a maximum velocity of 4.6 m/s. Wall shear stress of 340 Pa exceeded the threshold for effective debridement, and an apical pressure of 8.4 kPa was recorded at the apical wall. The TruNatomy needle produced uniform, low-magnitude wall shear stress along the lateral vent-facing canal walls, with limited apical irrigant exchange.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148972010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative Management of a Partially Impacted Mandibular Second Molar at Risk of Inferior Alveolar Nerve Injury During Extraction: Case Report. 下颌第二磨牙部分阻生拔牙时下牙槽神经损伤风险的保守治疗:1例报告。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-31 DOI: 10.1111/aej.70119
Saaid Al Shehadat, Mohamed Nidal Al Khouly, Shishir Ram Shetty, Apathsakayan Renugalakshmi, Venkateshbabu Nagendrababu, Paul M H Dummer
{"title":"Conservative Management of a Partially Impacted Mandibular Second Molar at Risk of Inferior Alveolar Nerve Injury During Extraction: Case Report.","authors":"Saaid Al Shehadat, Mohamed Nidal Al Khouly, Shishir Ram Shetty, Apathsakayan Renugalakshmi, Venkateshbabu Nagendrababu, Paul M H Dummer","doi":"10.1111/aej.70119","DOIUrl":"https://doi.org/10.1111/aej.70119","url":null,"abstract":"<p><p>This case report describes the conservative management of an incompletely erupted, subgingivally positioned mandibular right second molar with extensive caries and periapical pathosis in close anatomical relationship to the IAN canal. Complete extraction was initially considered as a provisional treatment option; however, CBCT revealed partial encirclement of the IAN canal by the roots, leading to a conservative treatment plan comprising root canal treatment followed by coronectomy. The initial treatment involved the extraction of tooth 48, followed by root canal treatment and tooth restoration of tooth 47; the patient declined coronectomy. At the 1-year follow-up, the patient was asymptomatic and periapical radiographs and CBCT scans indicated substantial periapical healing and preservation of the IAN. This case illustrates the role of CBCT-guided conservative endodontic management of impacted teeth as a viable alternative to extraction in high-risk anatomical situations.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative Pain During Tagger Hybrid Thermomechanical Compaction Technique in Single-Visit Treatment of Necrotic Teeth: A Prospective Single-Arm Observational Study. Tagger复合热机械压实技术在坏死牙单次治疗中的术中疼痛:一项前瞻性单臂观察研究。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-26 DOI: 10.1111/aej.70118
Ricardo Machado, Stella Maria Glaci Reinke, Divya Reddy, Alexandre Kowalczuck, Everdan Carneiro, Sergio Aparecido Ignacio, Ulisses Xavier da Silva Neto
{"title":"Intraoperative Pain During Tagger Hybrid Thermomechanical Compaction Technique in Single-Visit Treatment of Necrotic Teeth: A Prospective Single-Arm Observational Study.","authors":"Ricardo Machado, Stella Maria Glaci Reinke, Divya Reddy, Alexandre Kowalczuck, Everdan Carneiro, Sergio Aparecido Ignacio, Ulisses Xavier da Silva Neto","doi":"10.1111/aej.70118","DOIUrl":"https://doi.org/10.1111/aej.70118","url":null,"abstract":"<p><p>This prospective single-arm observational clinical study evaluated intraoperative pain during root canal obturation using the Tagger hybrid thermomechanical compaction technique (THTCT) in necrotic teeth treated in a single visit. A total of 151 necrotic teeth from 151 patients aged 12-90 years (mean ± SD: 39.7 ± 17.9 years) were included. All teeth underwent standardised chemomechanical preparation and were obturated using the THTCT with EndoFill sealer. Immediately after thermomechanical compaction, patients were asked to rate their intraoperative pain intensity using a normalised pain scale. Demographic and clinical variables, including biological sex, tooth type, periapical diagnosis, and sealer extrusion, were also analysed. Intraoperative pain intensity was generally low and was not significantly associated with biological sex (p = 0.251), tooth type (p = 0.211), periapical diagnosis (p = 0.733), or sealer extrusion (p = 0.934). The THTCT was associated with minimal intraoperative pain, supporting its clinical safety, patient comfort, and cost-effectiveness.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stacked Ensemble Deep Learning Models for Accurate Detection and Size Stratification of Periapical Lesions on Intraoral Radiographs. 用于口内x线片根尖周病变准确检测和大小分层的堆叠集成深度学习模型。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-24 DOI: 10.1111/aej.70113
Seyyedeh Elham Mousavi, Mostafa Jafari, Marziyeh Tahmasbi, Mahshid Razavi, Sanaz Sharifi Shooshtari
{"title":"Stacked Ensemble Deep Learning Models for Accurate Detection and Size Stratification of Periapical Lesions on Intraoral Radiographs.","authors":"Seyyedeh Elham Mousavi, Mostafa Jafari, Marziyeh Tahmasbi, Mahshid Razavi, Sanaz Sharifi Shooshtari","doi":"10.1111/aej.70113","DOIUrl":"https://doi.org/10.1111/aej.70113","url":null,"abstract":"<p><p>Periapical lesions are challenging to detect on intraoral radiographs because of anatomical superimposition and reader variability. This study developed stacked deep learning ensembles for automated detection and radiographic size stratification of periapical lesions. In total, 146 radiographs comprising normal cases and three lesion-size categories were cropped around the root apex and augmented using predefined transformations. Five convolutional neural network backbones were trained, and their probability outputs were combined using multinomial logistic regression (MLR) and gradient boosting (XGBoost) meta-learners. On the internal hold-out test set, both ensembles performed better than the individual backbones. MLR achieved an accuracy of 0.96 and a macro-averaged ROC-AUC of 1.00, while XGBoost achieved an accuracy of 0.95 with a similar AUC. Both ensembles also achieved a sensitivity of 0.94 for lesions < 2 mm. These findings support further investigation of stacking for radiographic decision support, but optimistic estimates from this small, single-centre internal study require prospective multicentre external validation.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148815013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discuss the Rationale for Minimally Invasive Endodontics and the Merits and Demerits of the Concept. 讨论微创牙髓学的基本原理及其优缺点。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-17 DOI: 10.1111/aej.70111
Iris Mohan Li
{"title":"Discuss the Rationale for Minimally Invasive Endodontics and the Merits and Demerits of the Concept.","authors":"Iris Mohan Li","doi":"10.1111/aej.70111","DOIUrl":"https://doi.org/10.1111/aej.70111","url":null,"abstract":"<p><p>Minimally invasive endodontics (MIE) places emphasis on the conservation of sound tooth structure and viable pulp tissue during endodontic procedures such as root canal treatment (RCTx) and vital pulp therapy (VPT). The use of minimal access cavity designs and conservative canal preparation dimensions have been investigated as a way to improve the structural prognosis of endodontically-treated teeth, while VPT has gained popularity in recent years as a conservative alternative to RCTx in vital teeth. In this paper, the positive and negative impacts of MIE techniques on fracture resistance and root canal disinfection respectively in the current literature will be explored, with an emphasis on critical analysis of study methodologies, transferability of results to clinical practice and case selection guidelines for MIE techniques. Similarly, the evidence for the use of VPT as a treatment modality in MIE will also be explored.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sodium Diclofenac-Loaded Drug Delivery Microspheres: Impact on Calcium Hydroxide Paste Properties and Biological Response. 负载双氯芬酸钠的药物递送微球:对氢氧化钙糊体性质和生物反应的影响。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-17 DOI: 10.1111/aej.70117
João Vitor Oliveira de Amorim, Murilo Priori Alcalde, Leonardo Cabau, Rodrigo Ricci Vivan, Paulo Henrique Weckwerth, Marco Antonio Hungaro Duarte, Guilherme Ferreira da Silva
{"title":"Sodium Diclofenac-Loaded Drug Delivery Microspheres: Impact on Calcium Hydroxide Paste Properties and Biological Response.","authors":"João Vitor Oliveira de Amorim, Murilo Priori Alcalde, Leonardo Cabau, Rodrigo Ricci Vivan, Paulo Henrique Weckwerth, Marco Antonio Hungaro Duarte, Guilherme Ferreira da Silva","doi":"10.1111/aej.70117","DOIUrl":"https://doi.org/10.1111/aej.70117","url":null,"abstract":"<p><p>This study evaluated whether the incorporation of sodium diclofenac-loaded microspheres into a calcium hydroxide paste enhances antibiofilm activity while maintaining physicochemical properties and biocompatibility. Calcium hydroxide paste, calcium hydroxide combined with sodium diclofenac, and calcium hydroxide containing sodium diclofenac-loaded microspheres were evaluated against Enterococcus faecalis biofilms. Antibiofilm activity was assessed by biofilm biovolume and bacterial viability, whereas physicochemical properties were determined by pH and calcium ion release. Biocompatibility was investigated using a rat subcutaneous implantation model. The microsphere-containing formulation showed the lowest biofilm biovolume (17.47 μm<sup>3</sup>) and bacterial viability (5.64%), significantly outperforming calcium hydroxide alone (34.66 μm<sup>3</sup> and 50.08%, respectively; p < 0.001). All materials maintained an alkaline pH, sustained calcium ion release, and showed similar biocompatibility. Sodium diclofenac-loaded microspheres enhanced the antibiofilm activity of calcium hydroxide paste without adversely affecting physicochemical properties or biocompatibility.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Calcium Hydroxide Paste and Access Cavities on Fracture Strength of Mature and Simulated Immature Human Teeth: Ex Vivo. 氢氧化钙膏体和通道腔对成熟和模拟未成熟牙齿断裂强度的影响:离体。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-12 DOI: 10.1111/aej.70116
Naseem M Hashim, Paul V Abbott
{"title":"Effects of Calcium Hydroxide Paste and Access Cavities on Fracture Strength of Mature and Simulated Immature Human Teeth: Ex Vivo.","authors":"Naseem M Hashim, Paul V Abbott","doi":"10.1111/aej.70116","DOIUrl":"10.1111/aej.70116","url":null,"abstract":"<p><p>The aim was to examine whether a Ca(OH)<sub>2</sub> paste affects fracture strength of teeth. Sixty extracted maxillary central incisors were prepared to simulate immature teeth. Another 40 were used as mature teeth. The ten groups (n = 10) were: (1) immature control; (2) immature + access; (3) immature + access + 1 m Ca(OH)<sub>2</sub>; (4) immature + access + 12 m Ca(OH)<sub>2</sub>; (5) immature + no access + 1 m Ca(OH)<sub>2</sub>; (6) immature + no access + 12 m Ca(OH)<sub>2</sub>; (7) mature + access + 1 m Ca(OH)<sub>2</sub>; (8) mature + access + 12 m Ca(OH)<sub>2</sub>; (9) mature control; (10) mature + access. After preparation and Ca(OH)<sub>2</sub> use, the teeth were tested in an impact machine to determine the impact energy required to fracture them. Mature teeth had higher fracture strengths than simulated immature teeth. Access cavities reduced fracture strength of simulated immature teeth but not mature teeth. Ca(OH)<sub>2</sub> alone did not affect fracture strength over 1 or 12 months. Combined effects of access cavity and 1 m Ca(OH)<sub>2</sub> affected fracture strength of simulated immature teeth.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical Investigation for the Effect of TheraCal LC on the Temperature Distribution Inside the Pulp 热处理LC对纸浆内部温度分布影响的数值研究。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-02-11 DOI: 10.1111/aej.70064
Bahra H. Agha, Farqad Rasheed Saeed
{"title":"Numerical Investigation for the Effect of TheraCal LC on the Temperature Distribution Inside the Pulp","authors":"Bahra H. Agha,&nbsp;Farqad Rasheed Saeed","doi":"10.1111/aej.70064","DOIUrl":"10.1111/aej.70064","url":null,"abstract":"<div>\u0000 \u0000 <p>This study evaluated the thermal effect of TheraCal LC on pulpal temperature during light curing in Class I and II cavities. A mandibular first molar model was developed using COMSOL Multiphysics, with enamel, dentine, pulp and restorative material. Simulations were performed under physiological conditions at 37°C for cavities with 0.5 and 1 mm remaining dentine thickness, and temperature changes were analysed at 2 and 5 mm curing distances. The model was validated against two experimental studies. Results showed that without TheraCal LC, temperature rises were minimal and below the damage threshold. However, TheraCal LC significantly increased intrapulpal temperature, particularly at 0.5 mm dentine thickness, with rises exceeding 12°C. Shorter curing distances (2 mm) also increased temperatures, and in all cases with TheraCal LC, ΔT surpassed the critical 5.5°C threshold. These findings indicate that TheraCal LC poses a thermal risk to pulpal tissue, especially in deep cavities with minimal dentine thickness.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"420-430"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Severity of Apical Periodontitis and Next-Generation Systemic Inflammatory Biomarkers 根尖牙周炎的严重程度与下一代系统性炎症生物标志物的关系。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-04-09 DOI: 10.1111/aej.70078
Gözde Akbal Dincer, Rezan Sungur Güzel
{"title":"The Relationship Between Severity of Apical Periodontitis and Next-Generation Systemic Inflammatory Biomarkers","authors":"Gözde Akbal Dincer,&nbsp;Rezan Sungur Güzel","doi":"10.1111/aej.70078","DOIUrl":"10.1111/aej.70078","url":null,"abstract":"<p>Apical periodontitis (AP) is an endodontic infection that may persist asymptomatically and be reflected in systemic inflammatory status. This study aimed to evaluate the association between radiographic severity of AP and next-generation systemic inflammatory biomarkers in systemically healthy adults. Archived clinical, radiographic and haematological data of 206 adult patients treated under general anaesthesia between 2021 and 2024 were retrospectively analysed. Patients were grouped according to Periapical Index (PAI) scores. Systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet inflammatory value (PIV) were calculated from routine blood counts. Severe AP (PAI scores 4–5) was associated with significantly higher SII, NLR, and PIV values (<i>p</i> &lt; 0.05). The number of teeth with PAI score 5 correlated positively with SII, NLR and PIV, whereas PLR showed no significant association. Greater severity of AP was associated with elevated systemic inflammatory indices. PIV may provide adjunctive information on systemic inflammatory response in patients with severe AP.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"518-525"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/aej.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, Characterisation and Antibacterial Activity of Reduced Graphene Oxide-Cuprous Oxide Nanocomposite Against Dual Species Biofilms Using Clsm 还原氧化石墨烯-氧化亚铜纳米复合材料的合成、表征及对双种生物膜的抑菌活性研究。
IF 1.7 4区 医学
Australian Endodontic Journal Pub Date : 2026-08-04 Epub Date: 2026-04-08 DOI: 10.1111/aej.70073
Aashna Dinesh, M. S. Prathap, Pradeep Kumar, Jeslee Ann Jose, Samreena Kalander, Satwik Varadraj
{"title":"Synthesis, Characterisation and Antibacterial Activity of Reduced Graphene Oxide-Cuprous Oxide Nanocomposite Against Dual Species Biofilms Using Clsm","authors":"Aashna Dinesh,&nbsp;M. S. Prathap,&nbsp;Pradeep Kumar,&nbsp;Jeslee Ann Jose,&nbsp;Samreena Kalander,&nbsp;Satwik Varadraj","doi":"10.1111/aej.70073","DOIUrl":"10.1111/aej.70073","url":null,"abstract":"<div>\u0000 \u0000 <p>Root canal irrigants are essential for biofilm elimination, with sodium hypochlorite (NaOCl) as the current gold standard, though limited by cytotoxicity and poor dentine penetration. This study assessed the antibacterial efficacy of a reduced graphene oxide–cuprous oxide (rGO–Cu<sub>2</sub>O) nanocomposite against <i>Enterococcus faecalis</i> and <i>Streptococcus mutans</i> biofilms. Thirty decoronated premolars were prepared with Protaper Next X5, and biofilms were cultured for 21 days. The rGO–Cu<sub>2</sub>O nanocomposite, synthesised using an 808 nm laser-assisted method and characterised by FE-SEM, XRD and XPS, was compared with 2.5% NaOCl and saline. Antibacterial activity was evaluated through CFU counts and confocal laser scanning microscopy. rGO–Cu<sub>2</sub>O showed significantly greater bacterial reduction than saline, with superior efficacy to NaOCl against <i>E. faecalis</i> and comparable effects against <i>S. mutans</i>. CLSM confirmed disruption of mature biofilms, indicating its promise as a novel endodontic irrigant.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"52 2","pages":"480-487"},"PeriodicalIF":1.7,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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