Anna Carolina Neves Leutz, Victor Augusto Benedicto Dos Santos, Ana Cristina Padilha Janini, Amanda Nowicki de Salles, Brenda Paula Figueiredo de Almeida Gomes, Adriana de Jesus Soares, Talita Tartari, Marina Angélica Marciano
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引用次数: 0
摘要
本研究旨在评估新推出的硅酸钙基密封剂BioRoot Flow的体外细胞相容性和生物活性，并与其他硅酸钙基密封剂（AH Plus Bioceramic sealer和BioRoot RCS）和环氧树脂基AH Plus Jet进行比较。NIH/3 T3成纤维细胞用于评估细胞活力、粘附和迁移。采用SEM、EDS、XRD对材料进行了表征。在72 h时，BioRoot RCS的细胞活力最高，而BioRoot Flow的贴壁细胞较少，迁移量减少。EDS显示了BioRoot Flow中的锆含量，XRD证实了所有硅酸钙基密封剂中都存在方解石。细胞行为的变化可能与化学成分和表面性质的差异有关，这突出了进一步研究的必要性。
In Vitro Assessment of the Effects of Endodontic Sealers on Cell Viability, Adhesion, and Migration.
This study aimed to evaluate the in vitro cytocompatibility and bioactivity of the newly launched calcium silicate-based sealer BioRoot Flow, compared with other calcium silicate-based sealers (AH Plus Bioceramic Sealer and BioRoot RCS) and the epoxy resin-based AH Plus Jet. NIH/3 T3 fibroblasts were used to assess cell viability, adhesion, and migration. Material characterisation was performed using SEM, EDS, and XRD. BioRoot RCS exhibited the highest cell viability, while BioRoot Flow showed fewer adherent cells and reduced migration at 72 h. EDS revealed zirconium content in BioRoot Flow, and XRD confirmed calcite presence in all calcium silicate-based sealers. Variations in cell behaviour may be related to differences in chemical composition and surface properties, highlighting the need for further investigation.
期刊介绍：
The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues.
The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses.
The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.
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