Jörg Philipp Tchorz, Nathalie Konstantiniuk, Johann Julian Alfons Sistig, Wilhelm Frank, Maria Lessani, Constantin von See, Benedikt Schneider
{"title":"Ideal Horizontal X-Ray Beam Angulation for Maxillary Molars. A Retrospective Clinical Study Using Cone-Beam Computed Tomography.","authors":"Jörg Philipp Tchorz, Nathalie Konstantiniuk, Johann Julian Alfons Sistig, Wilhelm Frank, Maria Lessani, Constantin von See, Benedikt Schneider","doi":"10.1111/aej.12970","DOIUrl":"https://doi.org/10.1111/aej.12970","url":null,"abstract":"<p><p>The aim of this study was to analyse cone-beam computed tomography (CBCT) images to determine the ideal horizontal X-ray beam angulations for maxillary first and second molars. CBCT scans from 85 patients were retrospectively analysed to measure the angles at which buccal root canals (MB, DB) of maxillary first (n = 170) and second (n = 157) molars superimpose the palatal one (P) at coronal and apical levels. The mean angles and standard deviations for both tooth types combined at which MB1 and MB2 overlap with P, as well as the angle at which DB overlaps with P, were 114.01° (±9.30), 119.47° (±11.05) and 87.48° (±12.02), respectively. Angles at coronal levels were higher for both tooth types and all canals. If maxillary molar teeth show no signs of tilt, rotation or unusual anatomy, a distal tube shift of > 18°, based on the orthoradial direction (90°), should be chosen to achieve ideal visual canal separation.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resolvin E1 Promotes the Resolution of Dental Pulp Inflammation and Induces Autophagy.","authors":"Jie Chen, Mao Ye, Wenhao Qian, Yunbo Xing","doi":"10.1111/aej.12971","DOIUrl":"https://doi.org/10.1111/aej.12971","url":null,"abstract":"<p><p>Although the inflammation-resolving properties of Resolvin E1 have been characterised, its effect on autophagy during pulpitis resolution remains unclear. We established a rat pulpitis model to investigate the changes in autophagy during Resolvin E1-mediated pulpitis resolution. Histological staining and gene quantification were performed to assess pulp tissue injury and changes in inflammation- and autophagy-related gene expression. In vivo, Resolvin E1 promoted dental tissue repair and reduced the expression of tumour necrosis factor-α, interleukin-1β, and CD68 in dental pulp tissues. Resolvin E1 significantly activated LC3II and Atg12 and decreased Atg5 level. Beclin1 expression was upregulated on day 1 and downregulated on day 3. In vitro, Resolvin E1 enhanced human dental pulp cell proliferation; reduced inflammatory marker expression; and regulated LC3II, Beclin1, Atg5, and Atg12 expression. Resolvin E1 could reduce inflammatory damage and induce autophagy response to protect dental pulp tissue.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Methodological Appraisal and Evidence-Based Insights on Guided Tissue Regeneration in Endodontic Surgery: An Umbrella Review of Systematic Reviews and Meta-Analyses.","authors":"Rahul Sharma, Kanaga Durga, Harshita Wadhwa, Saurabh Kumar Gupta","doi":"10.1111/aej.12967","DOIUrl":"https://doi.org/10.1111/aej.12967","url":null,"abstract":"<p><p>This study evaluated the methodological quality and synthesised evidence from systematic reviews on guided tissue regeneration (GTR) in endodontic surgery. A comprehensive search across multiple databases was conducted to identify systematic reviews published up to 21 November 2024, with no language restrictions. Methodological quality was assessed using the AMSTAR-2 tool, and primary study overlap using corrected covered area (CCA) metrics. Fourteen systematic reviews, including eight meta-analyses, were included. The CCA was 12.77%, indicating high overlap, and AMSTAR-2 revealed considerable methodological variability. The use of GTR, especially the combination of bone grafts and resorbable membranes, showed improved healing outcomes in through-and-through lesions. Adjunctive use of platelet concentrates appeared to enhance postoperative recovery. However, heterogeneity in study designs and the absence of long-term follow-up limit the strength of conclusions. Overall, GTR techniques, particularly those combining grafts and membranes, show promise in endodontic surgery, but more rigorous, well-designed studies and systematic reviews are required to reinforce clinical recommendations. Trial Registration: International Prospective Register of Systematic Reviews (PROSPERO) CRD42024546481.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jéssica Lopes Trindade, Lucas Machado Maracci, Renata Dornelles Morgental, Gabriela Salatino Liedke, Carlos Alexandre Souza Bier
{"title":"Cone Beam Computed Tomography Impact on Diagnosis, Treatment Planning and Confidence in Endodontic Decision-Making: A Systematic Review","authors":"Jéssica Lopes Trindade, Lucas Machado Maracci, Renata Dornelles Morgental, Gabriela Salatino Liedke, Carlos Alexandre Souza Bier","doi":"10.1111/aej.12964","DOIUrl":"10.1111/aej.12964","url":null,"abstract":"<div>\u0000 \u0000 <p>This systematic review evaluated how CBCT impacts diagnosis, treatment planning (TP) and confidence in endodontic cases compared to intraoral radiography (IR). PubMed/MEDLINE, Cochrane-CENTRAL, Embase, Scopus, LILACS, Web of Science and Google Scholar databases were searched. Information regarding changes in the diagnosis, TP and confidence after CBCT was evaluated. The methodological quality was assessed using QUADAS-2. Twenty-six studies were included, 10 classified as having a low risk of bias. Most studies focused on changes in TP (<i>n</i> = 10) or diagnosis in primary treatments (<i>n</i> = 7). Studies evaluating dental trauma showed the most significant improvement. CBCT impacted TP, increasing difficulty in choosing treatment for complex cases (external root resorption and complex root canal morphology) and often resulting in a more invasive treatment (i.e., tooth extraction). CBCT impacts diagnosis, TP and confidence in cases of complex endodontic treatments, often leading to more invasive treatments.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"536-553"},"PeriodicalIF":1.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriela Kato Bego, Graziela Bianchi Leoni, Elias Daniel Covas Rodrigues, Larissa Moreira Spinola de Castro Raucci, Walter Raucci Neto
{"title":"Conventional vs. Ready-To-Use Bioceramic Cements: In Vitro Bond Strength Performance in Blood-Contaminated Dentine","authors":"Gabriela Kato Bego, Graziela Bianchi Leoni, Elias Daniel Covas Rodrigues, Larissa Moreira Spinola de Castro Raucci, Walter Raucci Neto","doi":"10.1111/aej.12965","DOIUrl":"10.1111/aej.12965","url":null,"abstract":"<div>\u0000 \u0000 <p>This study evaluated the performance of MTA and ready-to-use cement (Bio C Repair) in dentine repair under different blood contamination conditions. 120 bovine root dentine-disks were divided into control and blood-contaminated groups and then subdivided on the basis of cement type and exposure time (immediate or 15-min delay). The control was stored in a humid environment at 37°C for 28 days, whereas the contaminated group was stored in blood. Push-out bond strength was assessed using a universal testing machine (1 mm/min). Three samples per subgroup underwent EDS-X and SEM analysis. MTA exhibited significantly lower bond strength than Bio C Repair (<i>p</i> < 0.001). Samples exposed to blood showed significantly lower bond strength than controls (<i>p</i> < 0.001). The 15-min delay reduced bond strength only in Bio C Repair samples (<i>p</i> = 0.045). It can be concluded that blood contamination reduced bond strength, with the ready-to-use material demonstrating superior performance compared to the conventional bioceramic cement.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"466-473"},"PeriodicalIF":1.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Finite Element Analysis of Stress Distribution in Various Sizes Internal Root Resorption Cavities Filled With Different Materials","authors":"Tunahan Aktas, Tugba Kosar","doi":"10.1111/aej.12962","DOIUrl":"10.1111/aej.12962","url":null,"abstract":"<div>\u0000 \u0000 <p>This study aimed to investigate the stress distribution on dentine, supporting tissues and restorative materials in simulated tooth models with various sized internal resorption cavities obturated with gutta-percha, MTA or Biodentine. A 3D finite element model was developed using Wheeler's dental atlas. The cortical and trabecular bone, lamina dura, and periodontal ligament were modelled. A healthy tooth served as the control, while the other models featured internal resorption cavities of various sizes in the middle third. In the treated models, the resorption cavities were restored with gutta-percha, MTA or Biodentine; the apical and coronal thirds were filled with gutta-percha. Seventeen models were subjected to a 100 N force at a 135° angle. Stress increased with resorption size but decreased after treatment. Gutta-percha models showed the highest stress on dentine and bone, while Biodentine had the lowest. However, Biodentine accumulated the most stress within the material. Larger resorption cavities increased stress, while Biodentine and MTA transmitted less stress to dentine than gutta-percha.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"446-457"},"PeriodicalIF":1.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tamyres Veleda Fonseca, Gabriel Lima Braz, Henrique Timm Vieira, Nadia de Souza Ferreira, Melissa Feres Damian
{"title":"Do CBCT and Clinical Experience Impact Decision-Making in Endodontic Diagnosis and Treatment Planning? A Before-After Study","authors":"Tamyres Veleda Fonseca, Gabriel Lima Braz, Henrique Timm Vieira, Nadia de Souza Ferreira, Melissa Feres Damian","doi":"10.1111/aej.12966","DOIUrl":"10.1111/aej.12966","url":null,"abstract":"<p>This before-after study evaluated the impact of cone beam computed tomography (CBCT) and clinical experience on diagnosis and treatment planning for endodontic cases, compared to periapical radiography (PR). 28 CBCT cases with corresponding PR images were assessed by five endodontic specialists and five final-year dental students in two stages, 30 days apart: first using PR images and then CBCT scans. McNemar and Wilcoxon signed-rank tests were applied, along with binary and ordinal logistic regressions, to assess changes in diagnosis and therapeutic decisions between imaging modality, evaluator experience, and perceived difficulty. Most evaluators changed their diagnostic and treatment decisions from PR to CBCT, particularly among students. Evaluator experience significantly influenced the difficulty of diagnosis and treatment planning, especially with CBCT. The interpretation of CBCT images increased decision-making difficulty for students while facilitating it for professionals. CBCT significantly influenced clinical decisions and perceived difficulty, with effects varying based on evaluator experience.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"474-482"},"PeriodicalIF":1.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/aej.12966","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of Incubation Duration on Bond Strength and Microhardness of Calcium Silicate-Based Materials","authors":"Emine Şimşek, Makbule Bilge Akbulut","doi":"10.1111/aej.12961","DOIUrl":"10.1111/aej.12961","url":null,"abstract":"<div>\u0000 \u0000 <p>The objective of this study was to investigate the effect of different incubation periods on the push-out bond strength and microhardness of calcium-silicate-based materials: MTA-Angelus, Biodentine and BIOfactor MTA. A total of 100 dentine discs were used for the push-out test. Three cavities were prepared on each dentine disc. Each cavity on the same disc was filled with MTA-Angelus, Biodentine or BIOfactor MTA. Half of the dentine samples were incubated at 37°C for 1 day, and the other half for 28 days (<i>n</i> = 50). Push-out testing was then performed. For the microhardness test, material discs were prepared by mixing the materials and placing them into Teflon moulds (<i>n</i> = 26). The samples were incubated at 37°C for either 1 day or 28 days (<i>n</i> = 13). Vickers microhardness testing was conducted. The data were statistically analysed. The results showed that Biodentine exhibited the highest bond strength and microhardness at both time points, while MTA-Angelus showed the lowest (<i>p</i> < 0.05). Overall, Biodentine demonstrated superior performance, while BIOfactor MTA showed promising but moderate results.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"438-445"},"PeriodicalIF":1.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paulo Oliveira Silva, Julia Godoi Lopes, Iago Ramirez, Helena Cristina de Assis, Vinícius Leite Rosa-e-Silva, Gustavo Alexandre de Castro-Vasconcelos, Antonio Miranda da Cruz-Filho, Renato Roperto, Manoel Damião de Sousa-Neto, Benedetta Ghezzi, Fabiane Carneiro Lopes-Olhê, Giovanni Mergoni, Jardel Francisco Mazzi-Chaves
{"title":"Enhanced Bond Strength and Adhesive Interface of Resin-Based Sealer to Root Dentine Using a Novel Single Multifunctional Endodontic Irrigant Solution","authors":"Paulo Oliveira Silva, Julia Godoi Lopes, Iago Ramirez, Helena Cristina de Assis, Vinícius Leite Rosa-e-Silva, Gustavo Alexandre de Castro-Vasconcelos, Antonio Miranda da Cruz-Filho, Renato Roperto, Manoel Damião de Sousa-Neto, Benedetta Ghezzi, Fabiane Carneiro Lopes-Olhê, Giovanni Mergoni, Jardel Francisco Mazzi-Chaves","doi":"10.1111/aej.12957","DOIUrl":"10.1111/aej.12957","url":null,"abstract":"<div>\u0000 \u0000 <p>This study aimed to evaluate the influence of a new multifunctional single endodontic irrigant on the push-out bond strength and adhesive interface between gutta-percha and an epoxy resin-based sealer and root dentine. Forty-eight human maxillary canines were randomly assigned to four irrigation protocols (<i>n</i> = 12): NaOCl 2.5% + EDTA 17% + saline (SHE), Triton solution + saline (T), Triton solution + EDTA 17% + saline (TE) and NaOCl 2.5% + Triton solution + saline (SHT). Root canals were prepared with the WaveOne Gold Large system and obturated using a single WaveOne Large cone with AH Plus sealer. The SHE group showed the highest bond strength (4.87 ± 0.84 MPa), significantly higher than those of the other groups (<i>p</i> < 0.001). Scanning Electron Microscopy (SEM) revealed better adaptation in SHE, whereas T, TE and SHT exhibited gaps. The new irrigant resulted in lower bond strength and poorer adaptation of the adhesive interface.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"423-430"},"PeriodicalIF":1.5,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Insight Into Laser Applications in Endodontic Dentistry: A Comprehensive Review","authors":"Khawlah Hameed Alharbi, Waad Talal AlMarwani, Razan Awadallah Alsulami, Faisal Turki Alghamdi","doi":"10.1111/aej.12959","DOIUrl":"10.1111/aej.12959","url":null,"abstract":"<div>\u0000 \u0000 <p>There is limited clinical information regarding the efficacy and safety of laser treatment in endodontics and dentistry. This comprehensive literature review discusses the clinical efficacy, advantages and limitations of laser use in these fields. Carbon dioxide (CO<sub>2</sub>), diode, erbium-doped yttrium aluminium garnet (Er: YAG), Er, Chromium (Cr): YAG, and neodymium (Nd): YAG lasers have been used in endodontic treatments. Laser technology has revolutionised endodontic treatment by enhancing disinfection, promoting healing, facilitating root canal treatment, improving canal shaping and decreasing pain associated with endodontic treatments. General dental care has improved by laser advancements in drilling, preparing cavities, reshaping the gingiva, teeth bleaching, addressing periodontal disease and diagnosis. Their high precision results in minimal disruption of adjacent tissues, which in turn minimises bleeding, decreases patient discomfort, and accelerates recovery times. Further clinical randomised studies are required to compare laser treatments with conventional methods, particularly in the context of cost-effectiveness.</p>\u0000 </div>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":"51 2","pages":"527-535"},"PeriodicalIF":1.5,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}