{"title":"Dual-Action Experimental Solvent Achieves Effective Removal of Aged Gutta-Percha and Bioceramic Sealer From Root Canals: A Micro-CT Evaluation.","authors":"Raid Abdullah Almnea","doi":"10.1111/aej.12977","DOIUrl":null,"url":null,"abstract":"<p><p>This study evaluated the effectiveness of an experimental dual-action solvent in removing aged bioceramic sealers (EndoSequence BC and AH Plus Bioceramic) from root canals, compared with established solvents. Forty-eight extracted mandibular premolars were obturated and aged for ten months before retreatment using saline (control), Endosolv R, GuttaClear, or an experimental solvent comprising a deep eutectic solvent and enzyme-loaded nanoparticles. Residual filling material was quantified via micro-computed tomography. The type of solvent significantly influenced removal efficiency, particularly at the apical level (p < 0.001). The experimental solvent achieved the highest median material removal in all root thirds, with values exceeding 92% apically and 100% in the middle third. Statistically significant differences were observed among solvents in the apical and middle regions. The experimental solvent demonstrated superior efficacy over conventional agents, highlighting its potential as a more effective option for retreatment procedures involving bioceramic sealers.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Endodontic Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/aej.12977","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
This study evaluated the effectiveness of an experimental dual-action solvent in removing aged bioceramic sealers (EndoSequence BC and AH Plus Bioceramic) from root canals, compared with established solvents. Forty-eight extracted mandibular premolars were obturated and aged for ten months before retreatment using saline (control), Endosolv R, GuttaClear, or an experimental solvent comprising a deep eutectic solvent and enzyme-loaded nanoparticles. Residual filling material was quantified via micro-computed tomography. The type of solvent significantly influenced removal efficiency, particularly at the apical level (p < 0.001). The experimental solvent achieved the highest median material removal in all root thirds, with values exceeding 92% apically and 100% in the middle third. Statistically significant differences were observed among solvents in the apical and middle regions. The experimental solvent demonstrated superior efficacy over conventional agents, highlighting its potential as a more effective option for retreatment procedures involving bioceramic sealers.
本研究评估了一种实验性双作用溶剂在根管中去除老化生物陶瓷密封剂(EndoSequence BC和AH Plus bioceramic)的有效性,并与现有溶剂进行了比较。48颗拔出的下颌前磨牙被封闭并陈化10个月,然后用生理盐水(对照)、Endosolv R、GuttaClear或含有深共晶溶剂和载酶纳米颗粒的实验溶剂进行再治疗。通过显微计算机断层扫描对残余填充材料进行量化。溶剂类型显著影响去除效率,特别是在根尖水平(p
期刊介绍:
The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues.
The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses.
The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.