Aging Male最新文献

{"title":"The impact of male genital self-image on depression, anxiety and sexual functions.","authors":"Adil Emrah Sonbahar","doi":"10.1080/13685538.2024.2363275","DOIUrl":"https://doi.org/10.1080/13685538.2024.2363275","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to examine the relationship between male genital self-perception and sexual functioning and depression anxieties.</p><p><strong>Method: </strong>The study included male patients who were referred to the andrology outpatient clinic between March 2022 and June 2022. Demographic data of the patients were recorded. Cigarette and alcohol consumption was also noted. The Male Genital Self Image Scale (MGSIS) questionnaire was used for the Genital Self Image(GSI) assessment, which consists of 7 questions. The International Index of Erectile Function (IIEF), composed of 15 questions, was used to evaluate sexual function. STAI-I, STAI-II, and BECK scales were used for depression and anxiety. The penis size of the patients was measured in a flask and stretched condition, and the midpenile circumference was recorded. Patients were compared with respect to GSI, depression, anxiety, and sexual functioning.</p><p><strong>Results: </strong>A total of 75 patients were included in the study. The mean age of the patients was 46.69 ± 11.32 (26<b>-</b>72), and the mean BMI was 27.82 ± 3.79 (22.46<b>-</b>40.40) kg/m². A slightly positive correlation was found between the patients' flask penis size and MGSIS-total scores (<i>r</i> = 0.260, <i>p</i> = .024) and IIEF-SF scores (<i>r</i> = 0.240, <i>p</i> = .038). There was a moderately positive correlation between the stretched penis size and IIEF-OS (<i>r</i> = 0.403, <i>p</i> < .001) and IIEF-SF (<i>r</i> = 0.354, <i>p</i> = .002). While the MGSIS-total score and the STAI-I and STAI-II scores had a moderate negative correlation, there was an advanced negative correlation between the MGSIS-total score and the BECK score.</p><p><strong>Conclusion: </strong>Disruption of men's genital self-perception is moderately related to their susceptibility to depression and anxiety. This situation affects the person's sexual performance and causes orgasm problems to increase.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2363275"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of risk factors for bladder neck contracture after transurethral endoscopic surgery for benign prostatic hyperplasia.","authors":"Yingbing Wu, Lei Huang, Can Liu, Shujun Bai, Yu Chen, Qiong Bao, Xing Luo, Jingzhen Zhu, Weihua Fu, Ji Zheng, Zhao Jiang, Bishao Sun","doi":"10.1080/13685538.2024.2429456","DOIUrl":"https://doi.org/10.1080/13685538.2024.2429456","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the risk factors of bladder neck contracture (BNC) after transurethral endoscopic surgery for benign prostatic hyperplasia (BPH), and to provide a reference basis for the clinic.</p><p><strong>Methods: </strong>Clinical data of patients who underwent transurethral endoscopic surgery in our hospital from December 2019 to May 2023 were retrospectively collected. The incidence and risk factors of BNC after transurethral endoscopic surgery were analyzed by multivariate logistic regression analysis.</p><p><strong>Results: </strong>A total of 420 cases were included in this study, of which 246 were treated with bipolar transurethral resection of the prostate (bTURP) and 174 with green light laser vaporization of the prostate (GL-PVP), and there was no statistically significant difference in the incidence of BNC when comparing these two types of operations. A total of 18 patients developed BNC after surgery, and the overall incidence of BNC was 4.29%. Multivariate logistic regression analysis showed that smaller preoperative prostate volume (<i>p</i> = 0.042), smoking history (<i>p</i> = 0.009), positive preoperative urine culture (<i>p</i> = 0.001), and prolonged postoperative catheterization days (<i>p</i> = 0.003) were independent risk factors of BNC.</p><p><strong>Conclusion: </strong>Smaller preoperative prostate volume, smoking history, positive preoperative urine culture, and prolonged postoperative indwelling catheterisation were independent risk factors for BNC.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2429456"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional influence between benign prostatic hyperplasia, prostate cancer, and prostatitis and mental disorders: two-sample and multivariate mendelian randomization analyses.","authors":"Xiangyu Chen, Congzhe Ren, Qihua Wang, Xiaoqiang Liu","doi":"10.1080/13685538.2024.2419853","DOIUrl":"https://doi.org/10.1080/13685538.2024.2419853","url":null,"abstract":"<p><strong>Background: </strong>We aimed to use Mendelian randomization (MR) to determine the causality between fifteen major mental disorders (MDs) and benign prostatic hyperplasia (BPH), prostate cancer (PCa), and prostatitis.</p><p><strong>Methods: </strong>The main MR analysis was performed using the inverse variance-weighted (IVW) method.</p><p><strong>Results: </strong>The study found that insomnia (odds ratio [OR], 1.6190; <i>p</i> = .0017) was significantly associated with an increased risk of BPH, and mood disorders (OR, 1.1590; <i>p</i> = .0221) was nominally associated with an increased risk of BPH. Conversely, BPH was suggestively associated with a low epilepsy risk (OR, 0.9988; <i>p</i> = .0043), and was nominally associated with an increased risk of insomnia (OR, 1.0061; <i>p</i> = .0291). Furthermore, attention deficit hyperactivity disorder (ADHD) was suggestively associated with a low PCa risk (OR = 0.9474; <i>p</i> = .0058). However, no causal relationship was observed between PCa and MDs. Finally, anorexia nervosa (OR, 1.1686; <i>p</i> = .0248) and depression (OR, 336.5383; <i>p</i> = .0308) were nominally positively correlated with prostatitis. Prostatitis was suggestively associated with increased risk of ADHD (OR, 1.0868; <i>p</i> = .0413).</p><p><strong>Conclusion: </strong>Our findings provide clinicians with a basis for developing programs to prevent or treat MDs and prostatic diseases.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2419853"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia and testosterone deficiency risk: insights from NHANES data analysis and a Mendelian randomization analysis.","authors":"Zhenming Zheng, Jiashan Pan, Ming Liu, Zhimin Chen, Lvwen Zhang, Jingjing Gao, Pan Gao, Xiansheng Zhang","doi":"10.1080/13685538.2024.2346312","DOIUrl":"https://doi.org/10.1080/13685538.2024.2346312","url":null,"abstract":"<p><strong>Background: </strong>Previous research has shown that testosterone deficiency (TD) increases the risk of anemia, but it is unclear whether anemia affects testosterone levels. This study investigated the influence of anemia on testosterone levels.</p><p><strong>Methods: </strong>Utilizing data from six NHANES cycles, including demographic, testosterone levels, and hemoglobin concentrations, we employed multivariable-adjusted logistic regression to investigate the relationship between anemia and testosterone levels. Moreover, a two-sample Mendelian randomization (MR) study employing genome-wide association study (GWAS) data examined the causal relationship. Kaplan-Meier survival estimation was used to compared the overall survival (OS) of anemic and nonanemic patients with low testosterone and normal testosterone levels.</p><p><strong>Results: </strong>The inclusion of 21,786 participants (2318 with anemia and19,468 without anemia) revealed that nonanemic patients exhibited higher testosterone levels than did anemic patients (<i>β</i> = 22.616, 95% CI: 3.873-41.359, <i>p</i> = 0.01807). MR analysis confirmed anemia as a cause of TD (OR = 1.045, 95% CI: 1.020-1.071, <i>p</i> < 0.001). Anemic males with low testosterone had reduced OS compared to those with normal levels (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Anemia emerged as a potential risk factor for TD, highlighting a bidirectional relationship between these conditions. Additional prospective investigations are essential for the validation and reinforcement of our findings.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2346312"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of body mass index, waist circumference, and 25-OH-D3 on the risk of pre-diabetes mellitus in the Chinese population.","authors":"Qianying Ou, Jingwen Yu, Leweihua Lin, Danhong Lin, Kaining Chen, Huibiao Quan","doi":"10.1080/13685538.2023.2297569","DOIUrl":"10.1080/13685538.2023.2297569","url":null,"abstract":"<p><p>This study aimed to investigate the associations between body mass index (BMI), waist circumference (WC), 25-hydroxy-vitamin D3 (25-OH-D3), and the risk of pre-diabetes mellitus (PDM), as well as their predictive values in identifying PDM. A total of 1688 participants were included in this cross-sectional investigation. Spearman's correlation analysis was used to assess the relationships between candidate indicators and PDM. The impact of indicators on PDM risk was determined by multivariate logistic regression. The receiver operating characteristic (ROC) analysis was performed to evaluate the prognostic value of indicators. Our study indicated a positive correlation between WC, BMI, and 25-OH-D3 and PDM. WC (OR = 1.05, 95% CI = 1.04-1.06, <i>p</i> < 0.001), BMI (OR = 1.11, 95% CI = 1.08-1.15, <i>p</i> < 0.001), and 25-OH-D3 (OR = 1.01, 95% CI = 1.00-1.02, <i>p</i> = 0.037) and an increased risk of PDM. Additionally, the ROC analysis demonstrated that WC (AUC = 0.651, Specificity = 55.00%, Sensitivity = 67.900%) had a higher diagnostic value for predicting PDM compared to the other variables (BMI, 25-OH-D3, TG, TC, LDL-C, HDL-C, and UA). A cut-off value of WC > 80.5 cm predicted PDM with both good sensitivity and specificity. Additionally, the cut-off value of waist circumference (WC) for men with prediabetes was 86.500, while for women with prediabetes, it was 76.500.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2297569"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139076023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there an association between daylight hours and serum testosterone levels in men?","authors":"Mark Livingston, Adrian Heald, Geoffrey Hackett, Harishnath Ramachandran, Sudarshan Ramachandran","doi":"10.1080/13685538.2024.2409189","DOIUrl":"https://doi.org/10.1080/13685538.2024.2409189","url":null,"abstract":"<p><strong>Background: </strong>Studies assessing variability of serum testosterone levels associated with seasonal environmental factors have been contradictory.</p><p><strong>Design: </strong>We assessed associations between the seasons and changes (δ) in seasonality indices and male serum total testosterone (δTT) variability.</p><p><strong>Patients and measurements: </strong>Data were collected in 144 men with paired serum TT samples (126 non-fasting/18 fasting) analysed at Walsall Manor Hospital, UK (52.3 degrees North). Seasonal factors (ambient temperature within 15 min of sampling, humidity, precipitation, duration of daylight on the day of sampling, monthly average ambient temperature, and precipitation) were obtained from local weather-station archives. Sign-rank test determined inter-sample differences between TT and seasonality indices. Linear regression analyses studied associations between δTT and δ seasonal indices in the total cohort and subgroups (stratified by medians of age, TT and men with paired non-fasting samples). Sign-rank determined whether serum TT differed between the seasons.</p><p><strong>Results: </strong>Median inter-sample interval was 63 days. No significant inter-sample differences were evident regarding serum TT levels and seasonality indices. No associations were noted between δTT and δ seasonality indices in the total cohort and subgroups stratified by age and TT. Interestingly, δ ambient temperature (<i>p</i> = 0.012) and daylight duration (<i>p</i> = 0.032) were inversely associated with δTT in the 126 men in the non-fasting group (dependent variable). Only a small degree of the variability in the δTT was accounted by the above-mentioned independent variables. The seasons did not appear to influence serum TT values.</p><p><strong>Conclusions: </strong>No relation was shown between seasonality and serum TT in the total cohort, thus possibly eliminating a confounding variable that could affect laboratory and clinical practice. It may be that seasonal variation in length of day is too modest at this latitude to demonstrate significant associations, hence our findings are latitude specific. We suggest that further data analysis to address this question in areas with greater seasonal variation would be appropriate.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2409189"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prostate-specific antigen, androgen, progesterone and oestrogen receptors in Benign prostatic hyperplasia: human tissues and animal model study.","authors":"Haohan Wang, Chengcheng Liu, Ziqiang Dong, Xiaobo Chen, Ping Zhang","doi":"10.1080/13685538.2024.2391380","DOIUrl":"https://doi.org/10.1080/13685538.2024.2391380","url":null,"abstract":"<p><strong>Background: </strong>Direct evidence for the relationship between a large prostate (≥80 ml) and androgen receptor/PSA signal remains lacking in benign prostatic hyperplasia (BPH). Our aim is to identify whether the cause of a large prostate is related to progesterone receptor (PGR) androgen receptor (AR), oestrogen receptor α, β (ERα,β) and prostate-specific antigen (PSA).</p><p><strong>Materials and methods: </strong>Surgical specimens of BPH in plasmakinetic resection of the prostate (PKRP) with three groups of different prostate-sizes with mean volumes of 25.97 ml, 63.80 ml, and 122.37 ml were collected for immunohistochemical analysis of the tissue microarray with PGR, AR, PSA and ERs. Rats were castrated and treated with testosterone replacement to explore androgen and PGR, AR and ERs expression levels in the prostate. Quantitative real-time reverse transcription polymerase chain reaction (Rt-PCR) for mRNA detection of above genes was conducted.</p><p><strong>Results: </strong>Immunoblotting, Rt-PCR and immunohistochemistry assays showed that PGR, PSA, AR, ERα expression levels were positively correlated with prostate size and that ERβ expression levels were negatively correlated with prostate volume. Animal experiments have shown that prostate volume is decreased in castrated rats with decreased PGR, AR, ERα and increased ERβ expression levels.</p><p><strong>Conclusion: </strong>PGR, AR, ERs signals can be regarded as important factors for large-sized prostates in BPH patients (≥100 ml).</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2391380"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular health of fathers with history of intracytoplasmic sperm injection.","authors":"Pengzhu Li, Magdalena Langer, Theresa Vilsmaier, Marie Kramer, Franziska Sciuk, Brenda Kolbinger, André Jakob, Nina Rogenhofer, Robert Dalla-Pozza, Christian Thaler, Nikolaus Alexander Haas, Felix Sebastian Oberhoffer","doi":"10.1080/13685538.2024.2360529","DOIUrl":"10.1080/13685538.2024.2360529","url":null,"abstract":"<p><strong>Objective: </strong>Studies suggest that men who undergo assisted reproductive technologies (ART) may have a higher risk of cardiovascular disease; however, limited data on this matter is available. This observational pilot study aimed to investigate the overall vascular health of fathers with history of intracytoplasmic sperm injection (ICSI) compared to fathers whose partners conceived spontaneously.</p><p><strong>Methods: </strong>Diet quality, physical activity, sedentary behavior as well as overall vascular function including the assessment of pulse wave analysis, intima-media thickness (cIMT), arterial stiffness of the common carotid artery (CCA) and blood lipids, were evaluated.</p><p><strong>Results: </strong>A total of 34 fathers with history of ICSI and 29 controls (48.49 [46.32 - 57.09] years <i>vs.</i> 47.19 [40.62 - 55.18] years, <i>p</i> = 0.061) were included. After adjusting for age, no significantly increased cardiovascular risk was detected regarding vascular function.</p><p><strong>Conclusions: </strong>The results suggest an unaltered cardiovascular risk profile in fathers with history of ICSI. In the future, prospective multicenter studies are required to validate these preliminary results.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2360529"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insulin-like peptide 3 (INSL3) as an indicator of leydig cell insufficiency (LCI) in Middle-aged and older men with hypogonadism: reference range and threshold.","authors":"Ravinder Anand-Ivell, Kee Heng, Leen Antonio, Gyorgy Bartfai, Felipe F Casanueva, Mario Maggi, Terence W O'Neill, Margus Punab, Giulia Rastrelli, Jolanta Slowikowska-Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick Cw Wu, Ilpo T Huhtaniemi, Richard Ivell","doi":"10.1080/13685538.2024.2346322","DOIUrl":"10.1080/13685538.2024.2346322","url":null,"abstract":"<p><p>Insulin-like peptide 3 (INSL3) is a circulating biomarker for Leydig cell functional capacity in men, also indicating Leydig Cell Insufficiency (LCI) and potential primary hypogonadism. Using results from large cohort studies we explore sources of biological and technical variance, and establish a reference range for adult men. It is constitutively secreted with little within-individual variation and reflects testicular capacity to produce testosterone. The main INSL3 assays available indicate good concordance with low technical variance; there is no effect of ethnicity. INSL3 declines with age from 35 years at about 15% per decade. Like low calculated free testosterone, and to a lesser extent low total testosterone, reduced INSL3 is significantly associated with increasing age-related morbidity, including lower overall sexual function, reflecting LCI. Consequently, low INSL3 (≤0.4 ng/ml; ca. <2 SD from the population mean) might serve as an additional biochemical marker in the assessment of functional hypogonadism (late-onset hypogonadism, LOH) where testosterone is in the borderline low range. Excluding individuals with low LCI (INSL3 ≤ 0.4 ng/ml) leads to an age-independent (> 35 years) reference range (serum) for INSL3 in the eugonadal population of 0.4 - 2.3 ng/ml, with low INSL3 prospectively identifying individuals at risk of increased future morbidity.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2346322"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 on the time to counseling and treatment of prostate cancer.","authors":"Dejan K Filipas, Randi M Pose, Phillip Marks, Pierre Tennstedt, Burkhard Beyer, Derya Tilki, Hendrik Isbarn, Tobias Maurer, Tim A Ludwig, Hans Heinzer, Thomas Steuber","doi":"10.1080/13685538.2024.2347465","DOIUrl":"https://doi.org/10.1080/13685538.2024.2347465","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates how the COVID-19 pandemic (CP) impacted the timeline between initial diagnosis (ID) of prostate carcinoma and subsequent therapy consultation (TC) or radical prostatectomy (RP) due to the implementation of a \"minimal contact concept,\" which postponed clinical examinations until the day of admission.</p><p><strong>Methods: </strong>We analyzed patient data from a tertiary care center from 2018 to September 2021. The focus was on comparing the time intervals from ID to TC and from ID to RP before and during the CP.</p><p><strong>Results: </strong>Of 12,255 patients, 6,073 (61.6%) were treated before and 3,791 (38.4%) during the CP. The median time from ID to TC reduced from 37 days (IQR: 21 - 58d) pre-CP to 32 days (IQR: 20 - 50d) during CP (<i>p</i> < 0.001). Similarly, the time from ID to RP decreased from 98 days (IQR: 70 - 141d) to 75 days (IQR: 55 - 108d; <i>p</i> < 0.001) during the CP. There was a significant decrease in low-risk tumor cases at ID (18.9% vs. 21.4%; <i>p</i> = 0.003) and post-RP (4% vs. 6.7%; <i>p</i> < 0.001) during the CP.</p><p><strong>Conclusion: </strong>Our findings suggest that the COVID-19 pandemic facilitated more timely treatment of prostate cancer, suggesting potential benefits for both low-risk and aggressive tumor management through expedited clinical procedures.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2347465"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}