Aging Male最新文献

{"title":"Association between handgrip strength and metabolic syndrome in relation to gender and adiposity among middle aged and older Saudi populations.","authors":"Shaea A Alkahtani, Ghedeir M Alshammari, Aishah Alzuwaydi, Abdulaziz Alfuhaid, Abeer A Al-Masri, Rizwan Qaisar, Syed Shahid Habib","doi":"10.1080/13685538.2024.2325146","DOIUrl":"10.1080/13685538.2024.2325146","url":null,"abstract":"<p><strong>Aim: </strong>This cross-sectional study investigated the association between metabolic syndrome (MetS) and handgrip strength (HGS) with respect to sex and adiposity in Saudi men (<i>n</i> = 287) and women (<i>n</i> = 268).</p><p><strong>Material and methods: </strong>Anthropometry, body composition, HGS, and blood biochemistry were measured. The average age of the study population was 57.65 ± 9.3 years (men = 55.1 ± 9.3 years, women = 60.4 ± 9.3 years). We report that HGS/body mass index (BMI), HGS/weight, and HGS/fat (%) were significantly higher in controls than in patients with MetS in men but not in women. According to the ROC analysis, relative HGS (RHGS) was higher than HGS alone in the association with MetS, which was significant for men (<i>p</i> < 0.01). At lower quartiles of HGS, the probability of MetS was higher in women, and the same was found in men in the lower quartiles of HGS/%Fat. Multinomial regression revealed significant associations between age and adiposity and MetS in men and HGS in women. Additionally, the linear regression of age, HGS, and weight exhibited significant associations between HGS with WC in both sexes.</p><p><strong>Conclusion: </strong>A higher risk of MetS in the lower quartiles of HGS was found in women, and adiposity moderated the relationship between HGS and MetS in men.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2325146"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140102919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of the safety and efficacy of 1470-nm diode laser enucleation of the prostate and plasmakinetic resection of prostate in the treatment of large volume benign prostatic hyperplasia (>80 ml).","authors":"Xiao Xiao, Xiao Maolin, Xiong Tao, Deng Xiaohong, Wang Jinzhong, Tong Wei, Chen Gaoliang, Tang Mengxi","doi":"10.1080/13685538.2023.2257307","DOIUrl":"10.1080/13685538.2023.2257307","url":null,"abstract":"<p><strong>Objective: </strong>To compare the efficacy and safety of 1470-nm diode laser enucleation of the prostate (DiLEP) with that of plasmakinetic resection of the prostate (PKRP) in treating patients with large benign prostatic hyperplasia (BPH > 80ml).</p><p><strong>Methods: </strong>The clinical data from 211 cases of BPH (>80 ml) were collected for analysis. The patients were divided into two groups: the PKRP group (<i>n</i> = 118) and the DiLEP group (<i>n</i> = 93), based on the surgical method used.</p><p><strong>Result: </strong>The DiLEP group demonstrated significantly lower surgical time (<i>p</i> < 0.001), intraoperative bleeding (<i>p</i> < 0.001), bladder flushing time (<i>p</i> = 0.003), indwelling catheter time (<i>p</i> < 0.005), and length of hospital stay (<i>p</i> = 0.018) compared to the PKRP group. However, the quality of the prostatectomy was significantly higher in the DiLEP group (<i>p</i> = 0.005). The Qmax for the DiLEP group was significantly higher than that of the PKRP group (<i>p</i> < 0.05). Compared to the PKRP group, the incidence of urinary incontinence in the DiLEP group increased significantly 4 weeks post-surgery (<i>p</i> = 0.026), although the need for blood transfusion during surgery was significantly reduced (<i>p</i> = 0.037).</p><p><strong>Conclusion: </strong>Both DiLEP and PKRP are safe and effective methods for treating large-volume BPH. However, DiLEP offers advantages such as more thorough glandular resection, shorter surgical time, reduced bleeding, quicker recovery, and fewer complications.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2257307"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with concomitant prostate cancer in benign prostatic hyperplasia patients aged 60 years and above.","authors":"Mengdi Wu, Kun Zheng, Yanjie Cao, Qiaoxiang Yin, Yue Hu, Qitao Ren, Huijing Zhu, Xiaohua Lan, Weiwei Zhu","doi":"10.1080/13685538.2024.2388529","DOIUrl":"https://doi.org/10.1080/13685538.2024.2388529","url":null,"abstract":"<p><strong>Objective: </strong>Prostate hyperplasia and cancer are more prevalent in middle-aged and elderly men. Previous studies have linked both disorders to androgen receptors. Herein, efforts were made to identify factors associated with prostate cancer in patients ≥60 years, aiming to enhance their health management.</p><p><strong>Methods: </strong>An analytical framework was established utilizing the \"Prostate Cancer Early Warning Dataset\" from the National Clinical Medical Science Data Center. Variables selection was conducted through LASSO regression, followed by multifactorial logistic stepwise regression to construct a predictive model.</p><p><strong>Results: </strong>A total of 1,502 patients with BPH and 294 with combined PCa were hereby included. Multivariate regression delineated several independent predictors of PCa coexistence, including age (OR [95% CI]: 1.06 [1.04-1.09], <i>p</i> < 0.001), fPSA/tPSA ratio (OR [95% CI]: 0.01 [0.002-0.05], <i>p</i> < 0.001), serum inorganic phosphorus (OR [95% CI]: 5.85 [2.61-13.15], <i>p</i> < 0.001), globulin levels (OR [95% CI]: 1.06 [1.02-1.11], <i>p</i> = 0.005), serum potassium (OR [95% CI]: 0.58 [0.40-0.86], <i>p</i> = 0.006), low-density lipoprotein (LDL) cholesterol (OR [95% CI]: 1.28 [1.06-1.54], <i>p</i> = 0.009), among others.</p><p><strong>Conclusion: </strong>The analysis revealed connections between PCa occurrence in men aged over 60 and BPH, along with specific serum biomarkers such as inorganic phosphorus, globulin, LDL cholesterol, lower fPSA/tPSA ratios and serum potassium.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2388529"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid impairment and male fertility: a narrative review of literature.","authors":"Valentina Anelli, Elisa Gatta, Ilenia Pirola, Andrea Delbarba, Mario Rotondi, Carlo Cappelli","doi":"10.1080/13685538.2024.2310303","DOIUrl":"10.1080/13685538.2024.2310303","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of thyroid function on male fertility, focusing on hypo- and hyperthyroidism.</p><p><strong>Methods: </strong>A PubMed/MEDLINE, Web of Science, and Scopus research was performed. Original studies in English published online up to 31 May 2023 were selected and reviewed. The final reference list was defined based on the relevance of each paper to the scope of this review.</p><p><strong>Results: </strong>The available data in animals (31 studies) and human (26 studies) showed conflicting results. However, thyroid dysfunction altered erection and ejaculation both in animal models than in men.</p><p><strong>Conclusion: </strong>Both hypothyroidism and hyperthyroidism seem to cause ejaculation and erectile dysfunction. Hence, Guidelines recommend against the systematic screening for thyroid disorders in the men in sub-fertile couples, but only in men with ejaculation and erectile dysfunction and/or altered semen parameters.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2310303"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of male genital self-image on depression, anxiety and sexual functions.","authors":"Adil Emrah Sonbahar","doi":"10.1080/13685538.2024.2363275","DOIUrl":"https://doi.org/10.1080/13685538.2024.2363275","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to examine the relationship between male genital self-perception and sexual functioning and depression anxieties.</p><p><strong>Method: </strong>The study included male patients who were referred to the andrology outpatient clinic between March 2022 and June 2022. Demographic data of the patients were recorded. Cigarette and alcohol consumption was also noted. The Male Genital Self Image Scale (MGSIS) questionnaire was used for the Genital Self Image(GSI) assessment, which consists of 7 questions. The International Index of Erectile Function (IIEF), composed of 15 questions, was used to evaluate sexual function. STAI-I, STAI-II, and BECK scales were used for depression and anxiety. The penis size of the patients was measured in a flask and stretched condition, and the midpenile circumference was recorded. Patients were compared with respect to GSI, depression, anxiety, and sexual functioning.</p><p><strong>Results: </strong>A total of 75 patients were included in the study. The mean age of the patients was 46.69 ± 11.32 (26<b>-</b>72), and the mean BMI was 27.82 ± 3.79 (22.46<b>-</b>40.40) kg/m². A slightly positive correlation was found between the patients' flask penis size and MGSIS-total scores (<i>r</i> = 0.260, <i>p</i> = .024) and IIEF-SF scores (<i>r</i> = 0.240, <i>p</i> = .038). There was a moderately positive correlation between the stretched penis size and IIEF-OS (<i>r</i> = 0.403, <i>p</i> < .001) and IIEF-SF (<i>r</i> = 0.354, <i>p</i> = .002). While the MGSIS-total score and the STAI-I and STAI-II scores had a moderate negative correlation, there was an advanced negative correlation between the MGSIS-total score and the BECK score.</p><p><strong>Conclusion: </strong>Disruption of men's genital self-perception is moderately related to their susceptibility to depression and anxiety. This situation affects the person's sexual performance and causes orgasm problems to increase.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2363275"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of risk factors for bladder neck contracture after transurethral endoscopic surgery for benign prostatic hyperplasia.","authors":"Yingbing Wu, Lei Huang, Can Liu, Shujun Bai, Yu Chen, Qiong Bao, Xing Luo, Jingzhen Zhu, Weihua Fu, Ji Zheng, Zhao Jiang, Bishao Sun","doi":"10.1080/13685538.2024.2429456","DOIUrl":"https://doi.org/10.1080/13685538.2024.2429456","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the risk factors of bladder neck contracture (BNC) after transurethral endoscopic surgery for benign prostatic hyperplasia (BPH), and to provide a reference basis for the clinic.</p><p><strong>Methods: </strong>Clinical data of patients who underwent transurethral endoscopic surgery in our hospital from December 2019 to May 2023 were retrospectively collected. The incidence and risk factors of BNC after transurethral endoscopic surgery were analyzed by multivariate logistic regression analysis.</p><p><strong>Results: </strong>A total of 420 cases were included in this study, of which 246 were treated with bipolar transurethral resection of the prostate (bTURP) and 174 with green light laser vaporization of the prostate (GL-PVP), and there was no statistically significant difference in the incidence of BNC when comparing these two types of operations. A total of 18 patients developed BNC after surgery, and the overall incidence of BNC was 4.29%. Multivariate logistic regression analysis showed that smaller preoperative prostate volume (<i>p</i> = 0.042), smoking history (<i>p</i> = 0.009), positive preoperative urine culture (<i>p</i> = 0.001), and prolonged postoperative catheterization days (<i>p</i> = 0.003) were independent risk factors of BNC.</p><p><strong>Conclusion: </strong>Smaller preoperative prostate volume, smoking history, positive preoperative urine culture, and prolonged postoperative indwelling catheterisation were independent risk factors for BNC.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2429456"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional influence between benign prostatic hyperplasia, prostate cancer, and prostatitis and mental disorders: two-sample and multivariate mendelian randomization analyses.","authors":"Xiangyu Chen, Congzhe Ren, Qihua Wang, Xiaoqiang Liu","doi":"10.1080/13685538.2024.2419853","DOIUrl":"https://doi.org/10.1080/13685538.2024.2419853","url":null,"abstract":"<p><strong>Background: </strong>We aimed to use Mendelian randomization (MR) to determine the causality between fifteen major mental disorders (MDs) and benign prostatic hyperplasia (BPH), prostate cancer (PCa), and prostatitis.</p><p><strong>Methods: </strong>The main MR analysis was performed using the inverse variance-weighted (IVW) method.</p><p><strong>Results: </strong>The study found that insomnia (odds ratio [OR], 1.6190; <i>p</i> = .0017) was significantly associated with an increased risk of BPH, and mood disorders (OR, 1.1590; <i>p</i> = .0221) was nominally associated with an increased risk of BPH. Conversely, BPH was suggestively associated with a low epilepsy risk (OR, 0.9988; <i>p</i> = .0043), and was nominally associated with an increased risk of insomnia (OR, 1.0061; <i>p</i> = .0291). Furthermore, attention deficit hyperactivity disorder (ADHD) was suggestively associated with a low PCa risk (OR = 0.9474; <i>p</i> = .0058). However, no causal relationship was observed between PCa and MDs. Finally, anorexia nervosa (OR, 1.1686; <i>p</i> = .0248) and depression (OR, 336.5383; <i>p</i> = .0308) were nominally positively correlated with prostatitis. Prostatitis was suggestively associated with increased risk of ADHD (OR, 1.0868; <i>p</i> = .0413).</p><p><strong>Conclusion: </strong>Our findings provide clinicians with a basis for developing programs to prevent or treat MDs and prostatic diseases.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2419853"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia and testosterone deficiency risk: insights from NHANES data analysis and a Mendelian randomization analysis.","authors":"Zhenming Zheng, Jiashan Pan, Ming Liu, Zhimin Chen, Lvwen Zhang, Jingjing Gao, Pan Gao, Xiansheng Zhang","doi":"10.1080/13685538.2024.2346312","DOIUrl":"https://doi.org/10.1080/13685538.2024.2346312","url":null,"abstract":"<p><strong>Background: </strong>Previous research has shown that testosterone deficiency (TD) increases the risk of anemia, but it is unclear whether anemia affects testosterone levels. This study investigated the influence of anemia on testosterone levels.</p><p><strong>Methods: </strong>Utilizing data from six NHANES cycles, including demographic, testosterone levels, and hemoglobin concentrations, we employed multivariable-adjusted logistic regression to investigate the relationship between anemia and testosterone levels. Moreover, a two-sample Mendelian randomization (MR) study employing genome-wide association study (GWAS) data examined the causal relationship. Kaplan-Meier survival estimation was used to compared the overall survival (OS) of anemic and nonanemic patients with low testosterone and normal testosterone levels.</p><p><strong>Results: </strong>The inclusion of 21,786 participants (2318 with anemia and19,468 without anemia) revealed that nonanemic patients exhibited higher testosterone levels than did anemic patients (<i>β</i> = 22.616, 95% CI: 3.873-41.359, <i>p</i> = 0.01807). MR analysis confirmed anemia as a cause of TD (OR = 1.045, 95% CI: 1.020-1.071, <i>p</i> < 0.001). Anemic males with low testosterone had reduced OS compared to those with normal levels (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Anemia emerged as a potential risk factor for TD, highlighting a bidirectional relationship between these conditions. Additional prospective investigations are essential for the validation and reinforcement of our findings.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2346312"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of body mass index, waist circumference, and 25-OH-D3 on the risk of pre-diabetes mellitus in the Chinese population.","authors":"Qianying Ou, Jingwen Yu, Leweihua Lin, Danhong Lin, Kaining Chen, Huibiao Quan","doi":"10.1080/13685538.2023.2297569","DOIUrl":"10.1080/13685538.2023.2297569","url":null,"abstract":"<p><p>This study aimed to investigate the associations between body mass index (BMI), waist circumference (WC), 25-hydroxy-vitamin D3 (25-OH-D3), and the risk of pre-diabetes mellitus (PDM), as well as their predictive values in identifying PDM. A total of 1688 participants were included in this cross-sectional investigation. Spearman's correlation analysis was used to assess the relationships between candidate indicators and PDM. The impact of indicators on PDM risk was determined by multivariate logistic regression. The receiver operating characteristic (ROC) analysis was performed to evaluate the prognostic value of indicators. Our study indicated a positive correlation between WC, BMI, and 25-OH-D3 and PDM. WC (OR = 1.05, 95% CI = 1.04-1.06, <i>p</i> < 0.001), BMI (OR = 1.11, 95% CI = 1.08-1.15, <i>p</i> < 0.001), and 25-OH-D3 (OR = 1.01, 95% CI = 1.00-1.02, <i>p</i> = 0.037) and an increased risk of PDM. Additionally, the ROC analysis demonstrated that WC (AUC = 0.651, Specificity = 55.00%, Sensitivity = 67.900%) had a higher diagnostic value for predicting PDM compared to the other variables (BMI, 25-OH-D3, TG, TC, LDL-C, HDL-C, and UA). A cut-off value of WC > 80.5 cm predicted PDM with both good sensitivity and specificity. Additionally, the cut-off value of waist circumference (WC) for men with prediabetes was 86.500, while for women with prediabetes, it was 76.500.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2297569"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139076023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there an association between daylight hours and serum testosterone levels in men?","authors":"Mark Livingston, Adrian Heald, Geoffrey Hackett, Harishnath Ramachandran, Sudarshan Ramachandran","doi":"10.1080/13685538.2024.2409189","DOIUrl":"https://doi.org/10.1080/13685538.2024.2409189","url":null,"abstract":"<p><strong>Background: </strong>Studies assessing variability of serum testosterone levels associated with seasonal environmental factors have been contradictory.</p><p><strong>Design: </strong>We assessed associations between the seasons and changes (δ) in seasonality indices and male serum total testosterone (δTT) variability.</p><p><strong>Patients and measurements: </strong>Data were collected in 144 men with paired serum TT samples (126 non-fasting/18 fasting) analysed at Walsall Manor Hospital, UK (52.3 degrees North). Seasonal factors (ambient temperature within 15 min of sampling, humidity, precipitation, duration of daylight on the day of sampling, monthly average ambient temperature, and precipitation) were obtained from local weather-station archives. Sign-rank test determined inter-sample differences between TT and seasonality indices. Linear regression analyses studied associations between δTT and δ seasonal indices in the total cohort and subgroups (stratified by medians of age, TT and men with paired non-fasting samples). Sign-rank determined whether serum TT differed between the seasons.</p><p><strong>Results: </strong>Median inter-sample interval was 63 days. No significant inter-sample differences were evident regarding serum TT levels and seasonality indices. No associations were noted between δTT and δ seasonality indices in the total cohort and subgroups stratified by age and TT. Interestingly, δ ambient temperature (<i>p</i> = 0.012) and daylight duration (<i>p</i> = 0.032) were inversely associated with δTT in the 126 men in the non-fasting group (dependent variable). Only a small degree of the variability in the δTT was accounted by the above-mentioned independent variables. The seasons did not appear to influence serum TT values.</p><p><strong>Conclusions: </strong>No relation was shown between seasonality and serum TT in the total cohort, thus possibly eliminating a confounding variable that could affect laboratory and clinical practice. It may be that seasonal variation in length of day is too modest at this latitude to demonstrate significant associations, hence our findings are latitude specific. We suggest that further data analysis to address this question in areas with greater seasonal variation would be appropriate.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2409189"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}