IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-10 DOI: 10.1080/13685538.2024.2436862

Phillip Marks, Roland Dahlem, Margit Fisch, Victor M Schuettfort, Malte W Vetterlein, Dejan K Filipas, Tim A Ludwig

{"title":"Artificial urinary sphincter implantation after transperineal open reconstruction of post-prostatectomy vesicourethral anastomotic stenosis.","authors":"Phillip Marks, Roland Dahlem, Margit Fisch, Victor M Schuettfort, Malte W Vetterlein, Dejan K Filipas, Tim A Ludwig","doi":"10.1080/13685538.2024.2436862","DOIUrl":"https://doi.org/10.1080/13685538.2024.2436862","url":null,"abstract":"Purpose: This study evaluates the effectiveness of artificial urinary sphincter (AUS) implantation following transperineal reanastomosis in men with vesicourethral anastomotic stenosis (VUAS) and stress urinary incontinence (SUI) after radical prostatectomy (RP), focusing on long-term explantation rates and urinary continence.Methods: Patients treated between 2009 and 2020 were retrospectively analyzed. Those undergoing AUS implantation post-transperineal reanastomosis for recurrent VUAS, excluding cases with prior pelvic irradiation and overactive bladder, were included. Primary outcomes were AUS explantation rates and patient-reported continence. Median follow-up was calculated using reverse Kaplan-Meier estimates, and explantation-free survival illustrated via Kaplan-Meier analyses.Results: At final follow-up, 19 patients were included at a median follow-up of 79 months. Explantation occurred in 16% (N = 3) of cases, with a median time to explantation of 107 months. No urethral erosion was observed. Explantation-free survival at 2, 5, and 10 years was 100%, 87%, and 73%, respectively. The median number of pads/day decreased significantly postoperatively, with 78% (N = 14) reporting subjective continence and 89% (N = 16) achieving social continence.Conclusion: AUS implantation following transperineal reanastomosis for VUAS post-RP offers favorable long-term outcomes, with low explantation rates and no erosion, making it a viable management strategy.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2436862"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Singular case report of familial hypocalciuric hypercalcemia: a rare diagnosis of hypercalcemia in the older people.

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-09 DOI: 10.1080/13685538.2024.2436877

Etienne Ojardias, Mélanie Leman, Ludovic Lafaie, Philippe Oriol, Paul Calmels, Thomas Celarier

{"title":"Singular case report of familial hypocalciuric hypercalcemia: a rare diagnosis of hypercalcemia in the older people.","authors":"Etienne Ojardias, Mélanie Leman, Ludovic Lafaie, Philippe Oriol, Paul Calmels, Thomas Celarier","doi":"10.1080/13685538.2024.2436877","DOIUrl":"https://doi.org/10.1080/13685538.2024.2436877","url":null,"abstract":"Objective: to report a case of familial hypocalciuric hypercalcemia (FHH) in an older patient and highlight the diagnostic challenges in geriatric populations.Case presentation: We report the diagnosis of FHH in an 88-year-old polypathological patient with hypercalcemia discovered during a check-up for cardiac decompensation. Despite a confusing clinical presentation with gout symptoms, including repeated episodes of knee arthritis, persistent hypercalcemia conducted further investigations. Biological tests excluded primary or hyperparathyroidism and malignancy-related hyperparathyroidism, confirming the diagnosis of FHH through the detection of an inhibitory mutation in the calcium-sensing receptor gene.Conclusion: This case suggests to clinicians the possibility of FHH in older patients with unexplained hypercalcemia. In geriatric patients, the diagnosis is complicated because of the poly-pathology: here hypercalcemia was associated with a confusing gout crisis, which was triggered by diuretic treatment for heart failure.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2436877"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of testicular histopathology with sperm retrieval success rates in men with idiopathic non-obstructive azoospermia. 特发性非梗阻性无精子症男性睾丸组织病理学与取精成功率的关系。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-14 DOI: 10.1080/13685538.2024.2436850

Thang Nguyen Cao, Bac Nguyen Hoai, Viet Dinh Huu, Emmanuele A Jannini

{"title":"Association of testicular histopathology with sperm retrieval success rates in men with idiopathic non-obstructive azoospermia.","authors":"Thang Nguyen Cao, Bac Nguyen Hoai, Viet Dinh Huu, Emmanuele A Jannini","doi":"10.1080/13685538.2024.2436850","DOIUrl":"https://doi.org/10.1080/13685538.2024.2436850","url":null,"abstract":"Introduction: Infertility is a major public health issue, with male factors alone contributing to 20-30% of cases. Non-obstructive azoospermia (NOA) is the most severe form, and although techniques like microdissection testicular sperm extraction (mTESE) offer hope, it remains challenging due to its uncertain causes. This study investigates the correlation between testicular histopathology and clinical parameters to enhance sperm retrieval (SR) prediction.Materials and methods: We reviewed 57 azoospermic men from Hanoi Medical University Hospital, recruited between January 2021 and September 2023. Inclusion criteria were confirmed azoospermia and exclusion of known NOA causes. All underwent mTESE with testicular biopsies classified into four histopathological patterns.Results: The patients' mean age was 31.75 ± 5.19 years. SR was successful in 19.3% (11/57). Higher follicle-stimulating hormone (FSH) levels were noted in SR-positive men (p = 0.02). Sertoli cell-only syndrome (SCOS) was the most common pattern. While we found a significant difference in SR rate between testicular histopathology, multivariate analysis showed no strong association. However, FSH levels were predictive of histopathology patterns.Conclusions: Idiopathic NOA (iNOA) represents over 60% of azoospermia cases. mTESE remains the gold standard, and FSH levels may help predict testicular histopathology patterns and improving patients prognosis of SR outcomes.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2436850"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the association between consumption of different types of beverages and erectile dysfunction in US men: evidence from NHANES 2003-2004 data.

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-10 DOI: 10.1080/13685538.2024.2438821

Liwei Wu, Bing Li, Hang Zhou, Xiaoqiang Liu

{"title":"Exploring the association between consumption of different types of beverages and erectile dysfunction in US men: evidence from NHANES 2003-2004 data.","authors":"Liwei Wu, Bing Li, Hang Zhou, Xiaoqiang Liu","doi":"10.1080/13685538.2024.2438821","DOIUrl":"https://doi.org/10.1080/13685538.2024.2438821","url":null,"abstract":"Background: The aim of this study was to examine the relationship between the type/frequency of consuming beverages and ED among men in America.Methods: We used data on erectile function and the frequency of beverage consumption from the National Health and Nutrition Examination Survey (NHANES) 2003-2004. Associations between ED and beverage consumption were analyzed using univariate and multivariate logistic regression. We also stratified by age and adjusted for potential confounders using propensity score matching (PSM).Results: After fully adjusting for covariates, logistic regression showed that regular grape juice consumption (≥ 5 times/week) was related to a lower prevalence of ED (OR = 0.21, 95% CI: 0.08-0.54, p = 0.001). Subgroup analyses found that this correlation remained significant for those over 40 years of age (all p < 0.05). After PSM adjustment, the association between grape juice consumption and ED remained statistically significant (OR = 0.12, 95% CI: 0.03-0.44, p = 0.001). Various beverage types, encompassing tomato, orange, apple, pineapple, and lemonade juices, as well as soft drinks, exhibited a correlation with ED in the initial univariate regression analysis.Conclusions: In men, regular intake of grape juice (≥ 5 times/week) was associated with a lower prevalence of ED, which was particularly significant in men over 40 years of age.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2438821"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of PDE5 inhibitors in middle-aged and old patients with and without hypogonadism. PDE5 抑制剂对伴有或不伴有性腺功能减退症的中老年患者的疗效和安全性。

IF 2.6 4区医学

Aging Male Pub Date : 2024-12-01 Epub Date: 2023-12-26 DOI: 10.1080/13685538.2023.2288347

Chunlin Wang, Hui Zhang, Fu Wang, Jun Guo, Jianlin Yuan, Guangdong Hou, Ming Gao, Zheng Li, Yan Zhang

{"title":"Efficacy and safety of PDE5 inhibitors in middle-aged and old patients with and without hypogonadism.","authors":"Chunlin Wang, Hui Zhang, Fu Wang, Jun Guo, Jianlin Yuan, Guangdong Hou, Ming Gao, Zheng Li, Yan Zhang","doi":"10.1080/13685538.2023.2288347","DOIUrl":"10.1080/13685538.2023.2288347","url":null,"abstract":"Purpose: Although several reviews have evaluated the use of PDE5 inhibitors (PDE5i) for treating erectile dysfunction (ED), their specific use in middle-aged and old patients has not been fully evaluated. Given that elderly patients with ED often have a complex combination of systemic and sexual health risk factors, the safety and efficacy of PDE5i in such a context are hereby reviewed.Materials and methods: A thorough examination of existing literature has been conducted on PubMed.Results: PDE5i has good safety and efficacy, but the situation is more complex for patients with hypogonadism than those with normal testosterone levels, with reduced responsiveness to PDE5i. In this case, combination therapy with testosterone is recommended, safe and effective.Conclusions: Eliminating or reducing reversible risk factors and controlling or slowing the development of irreversible factors is an important foundation for using PDE5i to treat ED in all patients, especially middle-aged and elderly ones.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2288347"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139038163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erectile dysfunction in patient with obstructive sleep apnea: effects of continuous positive airway pressure. 阻塞性睡眠呼吸暂停患者的勃起功能障碍：持续气道正压的影响。

IF 2.6 4区医学

Aging Male Pub Date : 2024-12-01 Epub Date: 2024-02-22 DOI: 10.1080/13685538.2024.2317165

Hyeyun Kim, Keun Tae Kim, Won Chul Shin, Kwang Ik Yang, Ji Yong Ha, Yong Won Cho

{"title":"Erectile dysfunction in patient with obstructive sleep apnea: effects of continuous positive airway pressure.","authors":"Hyeyun Kim, Keun Tae Kim, Won Chul Shin, Kwang Ik Yang, Ji Yong Ha, Yong Won Cho","doi":"10.1080/13685538.2024.2317165","DOIUrl":"10.1080/13685538.2024.2317165","url":null,"abstract":"Background: Obstructive sleep apnea (OSA) is linked to various health complications, including erectile dysfunction (ED), which is more prevalent in individuals with OSA. This study explored ED in Korean OSA patients and assessed the impact of continuous positive airway pressure (CPAP) therapy on ED.Methods: A total of 87 male patients with OSA from four different sleep centers underwent physical measurements and completed sleep and mental health (MH) questionnaires, including the Korean version of the International index of erectile function (IIEF), before and three months after initiating CPAP therapy.Results: After three months of CPAP therapy, the patients demonstrated a significant improvement in ED as measured on the IIEF. However, the study found no significant correlation between the duration of CPAP use and the improvement in IIEF score. It did identify the SF36 quality of life assessment as a significant factor influencing ED improvement after CPAP.Conclusions: ED is a prevalent issue that escalates with age and is associated with OSA. CPAP therapy has shown potential in alleviating ED symptoms, particularly in those with underlying psychological conditions, although further research is required to confirm these findings and understand the underlying mechanisms.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2317165"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of masturbation Premature ejaculation diagnostic tool in diagnosing premature ejaculation in men without vaginal intercourse over the past six months: an observational study. 手淫早泄诊断工具在诊断过去六个月未进行阴道性交的男性早泄方面的有效性：一项观察性研究。

IF 2.7 4区医学

Aging Male Pub Date : 2024-12-01 Epub Date: 2024-10-12 DOI: 10.1080/13685538.2024.2411286

Zeyu Zhu, Zhihui Mao, Chunlin Wang, Xiaohong Chen, Zhuojie Liu, Yan Zhang

{"title":"Effectiveness of masturbation Premature ejaculation diagnostic tool in diagnosing premature ejaculation in men without vaginal intercourse over the past six months: an observational study.","authors":"Zeyu Zhu, Zhihui Mao, Chunlin Wang, Xiaohong Chen, Zhuojie Liu, Yan Zhang","doi":"10.1080/13685538.2024.2411286","DOIUrl":"https://doi.org/10.1080/13685538.2024.2411286","url":null,"abstract":"Background: Premature ejaculation (PE) is a common concern for men and their partners, but current diagnostic tools mainly focus on men who have vaginal intercourse. The Masturbation Premature Ejaculation Diagnostic Tool (MPEDT) was created to address this gap, but its effectiveness for men who only engage in self-masturbation has not been studied. This research aimed to determine the frequency of self-reported PE patients who do not have vaginal intercourse and to evaluate the diagnostic accuracy of MPEDT for this group.Method: The study involved 446 male patients aged 18 to 40, and 40 non-self-reported-PE and non-vaginal-intercourse healthy males. Participants completed the MPEDT questionnaire and reported their recent six-months sex frequency.Result: Among the patients seeking treatment for PE, 21.75% had not engaged in vaginal intercourse in the past six months. Of the PE patients who completed the MPEDT questionnaire (86 patients), 90.7% were diagnosed with masturbatory-PE (MPE). The sensitivity for self-reported MPE and specificity for self-reported non-MPE were 93.02% and 72.5%, respectively.Discussion: For patients who have not had vaginal intercourse in the past six months but engage in masturbation and seek treatment for PE, the PEDT may not effectively assess their ejaculatory function. The MPEDT, however, can effectively evaluate their ejaculatory function. This study also emphasizes the need for diagnostic tools tailored to this population.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2411286"},"PeriodicalIF":2.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The efficacy of platelet rich plasma in the treatment of erectile dysfunction: a systematic review and meta-analysis of randomized controlled trials. 富血小板血浆治疗勃起功能障碍的疗效：随机对照试验的系统回顾和荟萃分析。

IF 2.6 4区医学

Aging Male Pub Date : 2024-12-01 Epub Date: 2024-06-04 DOI: 10.1080/13685538.2024.2358944

Qiancheng Mao, Yingying Yang, Yang Liu, Hongquan Liu, Gonglin Tang, Xiaofeng Wang, Yuanshan Cui, Jitao Wu

{"title":"The efficacy of platelet rich plasma in the treatment of erectile dysfunction: a systematic review and meta-analysis of randomized controlled trials.","authors":"Qiancheng Mao, Yingying Yang, Yang Liu, Hongquan Liu, Gonglin Tang, Xiaofeng Wang, Yuanshan Cui, Jitao Wu","doi":"10.1080/13685538.2024.2358944","DOIUrl":"10.1080/13685538.2024.2358944","url":null,"abstract":"Background: Erectile dysfunction (ED) is a common issue among males, and the use of platelet-rich plasma (PRP) therapy for treating ED has gained increasing attention, but there is still no conclusive evidence regarding its efficacy.Aim: To evaluate the efficacy of PRP therapy for ED.Methods: We systematically searched PubMed, Embase, Cochrane Library, and Web of Science databases up to November 2023 to identify randomized controlled trials (RCTs) on PRP therapy for ED. We used Review Manager version 5.4 for data analysis and management.Result: After applying inclusion and exclusion criteria for screening, a total of 4 studies involving 413 patients were finally included in our meta-analysis. According to our analysis, the PRP group showed significant advantages over the placebo group in terms of MCID at the first month (p = 0.03) and sixth months (p = 0.008), while there was no significant difference between the two groups at the third month (p = 0.19). Additionally, in terms of IIEF, PRP showed significantly better efficacy than placebo at the first, third, and sixth months (p < 0.00001).Conclusions: PRP shows more effectiveness in treating ED compared to placebo, offering hope as a potential alternative treatment for ED.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2358944"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel perspectives of testosterone therapy in men with functional hypogonadism: traversing the gaps of knowledge. 功能性性腺功能减退症男性睾酮治疗的新视角：跨越知识鸿沟。

IF 2.6 4区医学

Aging Male Pub Date : 2024-12-01 Epub Date: 2023-12-27 DOI: 10.1080/13685538.2023.2296460

Kristina Groti Antonič, Michael Zitzmann

{"title":"Novel perspectives of testosterone therapy in men with functional hypogonadism: traversing the gaps of knowledge.","authors":"Kristina Groti Antonič, Michael Zitzmann","doi":"10.1080/13685538.2023.2296460","DOIUrl":"10.1080/13685538.2023.2296460","url":null,"abstract":"Introduction: In the past decade, there has been a significant augmentation in the corpus of evidence pertaining to functional hypogonadism. Despite this, prevailing clinical guidelines continue to advise against the universal screening for hypogonadism in middle-aged and elderly males.Findings: Numerous randomized controlled trials have scrutinized the effects of testosterone therapy in males afflicted with type 2 diabetes and/or obesity. However, these guidelines uniformly assert that lifestyle modifications and weight reduction should be the primary intervention strategies in overweight and obese males, relegating testosterone therapy to a secondary, selective option. It is extensively documented that testosterone therapy can yield substantial improvements in various metabolic parameters as well as ameliorate symptoms of erectile dysfunction. Moreover, recent studies have demonstrated the potential of testosterone therapy in reversing type 2 diabetes in males with low-normal testosterone levels who are at elevated risk for this condition, in comparison to the outcomes achievable through lifestyle modifications alone.Conclusion: This focused review article aims to present a comprehensive update on the latest data concerning the innovative aspects of testosterone therapy in males with functional hypogonadism, particularly in the context of type 2 diabetes and/or obesity. Additionally, it will delve into the cardiovascular safety of such interventions within this high-risk demographic, with a special emphasis on insights gleaned from the TRAVERSE trial.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2296460"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139040970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolving horizons in renal angiomyolipoma: two decades of management strategies and clinical perspectives in a single institutional study. 肾血管肌脂肪瘤的发展前景：一项单一机构研究中二十年的管理策略和临床观点。

IF 2.6 4区医学

Aging Male Pub Date : 2024-12-01 Epub Date: 2024-05-06 DOI: 10.1080/13685538.2024.2346308

Ahmet Keles, Ayberk Iplikci, Ozgur Arikan, Meftun Culpan, Kursad Nuri Baydili, Ferhat Keser, Asif Yildirim

{"title":"Evolving horizons in renal angiomyolipoma: two decades of management strategies and clinical perspectives in a single institutional study.","authors":"Ahmet Keles, Ayberk Iplikci, Ozgur Arikan, Meftun Culpan, Kursad Nuri Baydili, Ferhat Keser, Asif Yildirim","doi":"10.1080/13685538.2024.2346308","DOIUrl":"https://doi.org/10.1080/13685538.2024.2346308","url":null,"abstract":"Objective: To assess various management options for renal angiomyolipoma (AML) to guide clinical practice.Methods: A single center retrospectively reviewed an AML series from 2002 to 2022. The image reports and chart reviews of patients who received two abdominal scans at least 6 months between the first and last scans were assessed.Results: A total of 203 patients with 209 tumors were identified and followed up for a median of 42.6 months. Active surveillance (AS) was the most frequently selected option (70.9% of cases). Interventions were required for 59 AMLs, of which 20 were treated with embolization, 29 with partial nephrectomy, 9 with radical nephrectomy, and 1 with radiofrequency (RF) ablation. The median size of the lesions at intervention was 5 cm. The average growth rate of the lesions was 0.12 cm/year, and there was a significant difference in the average growth rate of lesions ≤4 cm and those >4 cm (0.11 vs. 0.24 cm/year; p = 0.0046).Conclusion: This series on AMLs confirms that lesions >4 cm do not require early intervention based on size alone. Appropriately selected cases of renal AML can be managed by AS.KEYWORDS: Angiomyolipoma; active surveillance; embolization; nephrectomy; nephron-sparing surgery.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"27 1","pages":"2346308"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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