IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-03-04 DOI: 10.1080/13685538.2025.2472786

Zhongbao Zhou, Yongqiang Wang, Yumeng Chai, Tao Wang, Pu Yan, Yong Zhang, Xudong Yang

{"title":"The efficacy of platelet-rich plasma (PRP) alone or in combination with low intensity shock wave therapy (Li-SWT) in treating erectile dysfunction: a systematic review and meta-analysis of seven randomized controlled trials.","authors":"Zhongbao Zhou, Yongqiang Wang, Yumeng Chai, Tao Wang, Pu Yan, Yong Zhang, Xudong Yang","doi":"10.1080/13685538.2025.2472786","DOIUrl":"10.1080/13685538.2025.2472786","url":null,"abstract":"Background: The goal of this meta-analysis intended to identify the efficacy of platelet-rich plasma (PRP) alone or in combination with low intensity shock wave therapy (Li-SWT) as a therapy for erectile dysfunction (ED).Methods: This study integrated and analyzed the data using Cochrane method and GRADEpro GDT grading system. The registration number for this study was CRD42024618240.Result: Seven randomized controlled trials with 660 patients were analyzed. The results indicated that compared with the control group, IIEF score of patients in the PRP group improved significantly at 12-week (p = 0.03) and 24-week (p = 0.0004), while there was no significant difference at 4-week. The PRP group had no significant advantages over the control group in terms of MCID and SEP Q3. For peak systolic velocity, patients in the PRP group demonstrated greater improvement than those in the control group (p < 0.00001). Subgroup analysis revealed that adding PRP regimen can considerably improve IIEF scores of ED patients compared to using Li-SWT alone (p < 0.0001).Conclusion: PRP demonstrated a better efficacy in treating ED, especially during a follow-up period of 6 months. Compared with using Li-SWT alone, the addition of PRP can considerably improve the IIEF score of ED patients. These findings still required large-scale clinical trials for verification.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2472786"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial urinary sphincter implantation after transperineal open reconstruction of post-prostatectomy vesicourethral anastomotic stenosis. 前列腺切除术后膀胱尿道吻合口狭窄经会阴开放性重建术后人工尿道括约肌植入术。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-10 DOI: 10.1080/13685538.2024.2436862

Phillip Marks, Roland Dahlem, Margit Fisch, Victor M Schuettfort, Malte W Vetterlein, Dejan K Filipas, Tim A Ludwig

{"title":"Artificial urinary sphincter implantation after transperineal open reconstruction of post-prostatectomy vesicourethral anastomotic stenosis.","authors":"Phillip Marks, Roland Dahlem, Margit Fisch, Victor M Schuettfort, Malte W Vetterlein, Dejan K Filipas, Tim A Ludwig","doi":"10.1080/13685538.2024.2436862","DOIUrl":"https://doi.org/10.1080/13685538.2024.2436862","url":null,"abstract":"Purpose: This study evaluates the effectiveness of artificial urinary sphincter (AUS) implantation following transperineal reanastomosis in men with vesicourethral anastomotic stenosis (VUAS) and stress urinary incontinence (SUI) after radical prostatectomy (RP), focusing on long-term explantation rates and urinary continence.Methods: Patients treated between 2009 and 2020 were retrospectively analyzed. Those undergoing AUS implantation post-transperineal reanastomosis for recurrent VUAS, excluding cases with prior pelvic irradiation and overactive bladder, were included. Primary outcomes were AUS explantation rates and patient-reported continence. Median follow-up was calculated using reverse Kaplan-Meier estimates, and explantation-free survival illustrated via Kaplan-Meier analyses.Results: At final follow-up, 19 patients were included at a median follow-up of 79 months. Explantation occurred in 16% (N = 3) of cases, with a median time to explantation of 107 months. No urethral erosion was observed. Explantation-free survival at 2, 5, and 10 years was 100%, 87%, and 73%, respectively. The median number of pads/day decreased significantly postoperatively, with 78% (N = 14) reporting subjective continence and 89% (N = 16) achieving social continence.Conclusion: AUS implantation following transperineal reanastomosis for VUAS post-RP offers favorable long-term outcomes, with low explantation rates and no erosion, making it a viable management strategy.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2436862"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concerns over the association between sperm DNA fragmentation and male infertility. 对精子DNA断裂与男性不育之间关系的担忧。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-04-29 DOI: 10.1080/13685538.2025.2498945

Brijesh Sathian, Hanadi Al Hamad, Javed Iqbal

引用次数: 0

Association between visceral adiposity index and prostate cancer in men aged 40 years and older: a nationwide cross-sectional study. 40岁及以上男性内脏脂肪指数与前列腺癌之间的关系：一项全国性横断面研究。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-01-08 DOI: 10.1080/13685538.2024.2449341

Wentao Yao, Jiacheng Wu, Hongzhi Wang, Zongming Jia, Yinyi Zhou, Chendi Yang, Feng Xu, Ying Kong, Yuhua Huang

{"title":"Association between visceral adiposity index and prostate cancer in men aged 40 years and older: a nationwide cross-sectional study.","authors":"Wentao Yao, Jiacheng Wu, Hongzhi Wang, Zongming Jia, Yinyi Zhou, Chendi Yang, Feng Xu, Ying Kong, Yuhua Huang","doi":"10.1080/13685538.2024.2449341","DOIUrl":"https://doi.org/10.1080/13685538.2024.2449341","url":null,"abstract":"Objectives: This study aimed to elucidate the correlation of Visceral Adiposity Index (VAI) with prostate cancer (PCa) among men aged 40 years and older in the United States.Methods: Analysis included multivariate linear and logistic regression, smoothing curve fitting, and threshold effect evaluation using 2003-2010 National Health and Nutrition Examination Survey (NHANES) data. The stability of this relationship across demographic groups was assessed via subgroup analyses and interaction tests.Results: Among 2,768 participants, those with elevated VAI displayed lower total prostate-specific antigen (tPSA) levels and reduced PCa risk. Each VAI unit elevation corresponded to a 0.075 ng/mL tPSA reduction [-0.075 (-0.145, -0.005)] and 18.8% PCa risk reduction [0.812 (0.687, 0.960)]. Top-quartile VAI individuals exhibited 0.282 ng/mL reduced tPSA [-0.282 (-0.557, -0.007)] and 49.7% reduced PCa risk [0.503 (0.282, 0.896)] relative to bottom-quartile counterparts. This inverse relationship was more pronounced in men ≥70 years. Moreover, VAI-tPSA in other races demonstrated a U-shaped pattern, with a 2.09 inflection point. At the same time, a Mexican American subgroup exhibited an inverted U-shape for VAI and PCa risk, with a 1.42 inflection point.Conclusion: In men aged ≥70, VAI indicates an inverse PCa relationship. However, PSA-based PCa screening may be influenced in visceral-obese individuals aged <70.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2449341"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central obesity and its association with benign prostatic hyperplasia: insights from a cross-sectional study of NHANES 2001-2008. 中心性肥胖及其与良性前列腺增生的关系：来自2001-2008年NHANES横断面研究的见解

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-05-05 DOI: 10.1080/13685538.2025.2498943

Haoran Wang, Runhua Tang, Huimin Hou, Ming Liu, Yue Wang, Jianye Wang, Jianyong Liu, Jianlong Wang

{"title":"Central obesity and its association with benign prostatic hyperplasia: insights from a cross-sectional study of NHANES 2001-2008.","authors":"Haoran Wang, Runhua Tang, Huimin Hou, Ming Liu, Yue Wang, Jianye Wang, Jianyong Liu, Jianlong Wang","doi":"10.1080/13685538.2025.2498943","DOIUrl":"https://doi.org/10.1080/13685538.2025.2498943","url":null,"abstract":"Background: Benign prostatic hyperplasia (BPH) is a common condition that affects elderly men, but its relationship with central obesity in the American population has not been adequately elucidated.Methods: In this study, we included a total of 4,625 participants from the National Health and Nutrition Examination Survey (NHANES) database spanning from 2001 to 2008. We calculated indices related to central obesity for each participant and then employed univariate logistic regression, multivariate logistic regression, restricted cubic splines (RCS), and Akaike's Information Criterion (AIC) analysis.Results: we found that the indices of Weight, Waist Circumference (WC), waist-to-Height Ratio (WHtR), and Body Roundness Index (BRI) were significantly elevated in the BPH group. In terms of dietary intake, we found that the intake of total fat, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, and cholesterol was significantly higher in the BPH group, with polyunsaturated fatty acids and cholesterol meeting the criteria for both univariate and multivariate regression analyses.Conclusion: Weight, WC, WHtR, and BRI can effectively improve the prediction of BPH, which may be associated with the high intake of polyunsaturated fatty acids and cholesterol. Appropriately adjusting the types and total amount of fat intake may prevent the occurrence of prostatic hyperplasia.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2498943"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors influencing fall risk in geriatric patients with type 2 diabetes: a comprehensive analysis. 影响老年2型糖尿病患者跌倒风险的危险因素：一项综合分析

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-03-01 DOI: 10.1080/13685538.2025.2469614

Muharrem Bayrak, Kamber Kaşali, Merve Güner, Kenan Cadirci, Adil Furkan Kılıç, Dogan Nasır Binici

{"title":"Risk factors influencing fall risk in geriatric patients with type 2 diabetes: a comprehensive analysis.","authors":"Muharrem Bayrak, Kamber Kaşali, Merve Güner, Kenan Cadirci, Adil Furkan Kılıç, Dogan Nasır Binici","doi":"10.1080/13685538.2025.2469614","DOIUrl":"10.1080/13685538.2025.2469614","url":null,"abstract":"Background and objectives: Type 2 diabetes mellitus (T2DM) is a common chronic disease in the elderly. Comorbidities, especially neuropathy and retinopathy, significantly increase fall risk in this group. This study aimed to identify fall risk factors in older adults with T2DM.Materials and methods: From January to June 2024, 242 T2DM patients aged 65 and older were followed at the internal medicine outpatient clinic. Fall risk was assessed using the Performance Oriented Mobility Assessment (POMA), Hendrich II Fall Risk Model (HIIFRM), Barthel Activities of Daily Living Index, and Clinical Frailty Scale (CFS).Results: Among the patients (median age = 70 years), 41.3% had experienced at least one fall in the previous year. Factors, such as age and diabetes duration were associated with falls. Notably, hypoglycemia (aPR: 1.90, p = 0.017), polypharmacy (aPR: 2.39, p = 0.004), osteoarthritis (aPR: 2.48, p = 0.017), (aPR: 1.70, p = 0.025), and malnutrition (aPR: 1.90, p = 0.007) were independently associated with fall risk.Conclusions: Fall risk in elderly outpatients with T2DM was linked to various factors, including hospitalization, malnutrition, osteoarthritis, polypharmacy, neuropathy, and hypoglycemia. To mitigate this risk, patient-specific care plans are recommended.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2469614"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of outcomes from a geriatrician-led evidence-based falls prevention clinic: a retrospective study from Qatar. 老年医生主导的循证跌倒预防诊所的结果分析：来自卡塔尔的回顾性研究。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-03-20 DOI: 10.1080/13685538.2025.2481103

Hanadi Al Hamad, Brijesh Sathian

{"title":"Analysis of outcomes from a geriatrician-led evidence-based falls prevention clinic: a retrospective study from Qatar.","authors":"Hanadi Al Hamad, Brijesh Sathian","doi":"10.1080/13685538.2025.2481103","DOIUrl":"10.1080/13685538.2025.2481103","url":null,"abstract":"Background: Falls are an important health concern among older persons. This study attempted to evaluate the characteristics and risk factors of falls in older persons attending a geriatric falls clinic in Qatar, with a particular emphasis on the impact of the COVID-19 epidemic.Methods: A retrospective analysis was performed on 265 patients aged ≥ 65 years who visited the Falls Clinic between January 1, 2019, and November 28, 2021.Results: The study population showed a significant prevalence of chronic diseases, with hypertension (94.3%) and diabetes (87.5%) being the most common diseases. A substantial percentage of people reported functional difficulties, such as falls during the recent year and injuries. Interestingly, people recruited during the pandemic used assistive devices at a far higher proportion (46.9% vs. 5.5% previously). This group also reported higher rates of dizziness (54.9% vs. 26.7%, respectively) and pain (50.2% vs. 20.0%, respectively). Participants recruited during the epidemic had significantly elevated systolic blood pressure.Conclusion: This study showed an increased incidence of comorbidities and functional impairments in older adults who visited a fall prevention clinic in Qatar. These findings suggest that the pandemic may exacerbate population vulnerability.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2481103"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preservation of sexual function with blue laser vaporization in the treatment of benign prostatic hyperplasia: a prospective study. 蓝色激光汽化治疗良性前列腺增生保留性功能的前瞻性研究。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2025-03-04 DOI: 10.1080/13685538.2025.2473609

Zun-Jie Hu, Fei Liu, Bing-Hui Li, Yan Hu, Qiao Huang, Cong Zhu, Xian-Tao Zeng, Yong-Wei Zhao

{"title":"Preservation of sexual function with blue laser vaporization in the treatment of benign prostatic hyperplasia: a prospective study.","authors":"Zun-Jie Hu, Fei Liu, Bing-Hui Li, Yan Hu, Qiao Huang, Cong Zhu, Xian-Tao Zeng, Yong-Wei Zhao","doi":"10.1080/13685538.2025.2473609","DOIUrl":"10.1080/13685538.2025.2473609","url":null,"abstract":"Objective: Sexual function preservation is a paramount concern for patients undergoing benign prostatic hyperplasia (BPH) surgery, increasingly recognized by physicians. Blue laser vaporization, a novel approach for BPH treatment, has yet to be thoroughly investigated for its effects on sexual function. This prospective study assesses the impact of blue laser vaporization on sexual function in BPH patients, focusing on patient perceptions.Methods: This study prospectively enrolled BPH patients undergoing blue laser vaporization at our hospital since January 2023. We evaluated the treatment's effectiveness and its impact on preserving sexual function using standardized questionnaires. These included the International Index of Erectile Function (IIEF-5), the Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EjD), and both the International Consultation on Incontinence Modular Questionnaire for Male Lower Urinary Tract Symptoms (ICIQ-MLUTS) and its sexual function component (ICIQ-MLUTSsex).Results: We included 67 BPH patients with a median age of 65 years in this study, monitoring them for over three months. The results indicate that blue laser vaporization significantly improved International Prostate Symptom Score, Quality of Life, and ICIQ-MLUTS scores in BPH patients (p < 0.001), along with a reduction in post-void residual volume (p < 0.001). Importantly, there were no significant changes in the IIEF-5 score, MSHQ-EjD score, and ICIQ-MLUTSsex score, indicating preservation of sexual function post-surgery.Conclusion: Blue laser vaporization effectively alleviates lower urinary tract symptoms in BPH patients while preserving erectile and ejaculatory functions.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2473609"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of testicular histopathology with sperm retrieval success rates in men with idiopathic non-obstructive azoospermia. 特发性非梗阻性无精子症男性睾丸组织病理学与取精成功率的关系。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-14 DOI: 10.1080/13685538.2024.2436850

Thang Nguyen Cao, Bac Nguyen Hoai, Viet Dinh Huu, Emmanuele A Jannini

{"title":"Association of testicular histopathology with sperm retrieval success rates in men with idiopathic non-obstructive azoospermia.","authors":"Thang Nguyen Cao, Bac Nguyen Hoai, Viet Dinh Huu, Emmanuele A Jannini","doi":"10.1080/13685538.2024.2436850","DOIUrl":"https://doi.org/10.1080/13685538.2024.2436850","url":null,"abstract":"Introduction: Infertility is a major public health issue, with male factors alone contributing to 20-30% of cases. Non-obstructive azoospermia (NOA) is the most severe form, and although techniques like microdissection testicular sperm extraction (mTESE) offer hope, it remains challenging due to its uncertain causes. This study investigates the correlation between testicular histopathology and clinical parameters to enhance sperm retrieval (SR) prediction.Materials and methods: We reviewed 57 azoospermic men from Hanoi Medical University Hospital, recruited between January 2021 and September 2023. Inclusion criteria were confirmed azoospermia and exclusion of known NOA causes. All underwent mTESE with testicular biopsies classified into four histopathological patterns.Results: The patients' mean age was 31.75 ± 5.19 years. SR was successful in 19.3% (11/57). Higher follicle-stimulating hormone (FSH) levels were noted in SR-positive men (p = 0.02). Sertoli cell-only syndrome (SCOS) was the most common pattern. While we found a significant difference in SR rate between testicular histopathology, multivariate analysis showed no strong association. However, FSH levels were predictive of histopathology patterns.Conclusions: Idiopathic NOA (iNOA) represents over 60% of azoospermia cases. mTESE remains the gold standard, and FSH levels may help predict testicular histopathology patterns and improving patients prognosis of SR outcomes.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2436850"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Singular case report of familial hypocalciuric hypercalcemia: a rare diagnosis of hypercalcemia in the older people. 家族性低钙血症高钙血症的单一病例报告：老年人高钙血症的罕见诊断。

IF 2.7 4区医学

Aging Male Pub Date : 2025-12-01 Epub Date: 2024-12-09 DOI: 10.1080/13685538.2024.2436877

Etienne Ojardias, Mélanie Leman, Ludovic Lafaie, Philippe Oriol, Paul Calmels, Thomas Celarier

{"title":"Singular case report of familial hypocalciuric hypercalcemia: a rare diagnosis of hypercalcemia in the older people.","authors":"Etienne Ojardias, Mélanie Leman, Ludovic Lafaie, Philippe Oriol, Paul Calmels, Thomas Celarier","doi":"10.1080/13685538.2024.2436877","DOIUrl":"https://doi.org/10.1080/13685538.2024.2436877","url":null,"abstract":"Objective: to report a case of familial hypocalciuric hypercalcemia (FHH) in an older patient and highlight the diagnostic challenges in geriatric populations.Case presentation: We report the diagnosis of FHH in an 88-year-old polypathological patient with hypercalcemia discovered during a check-up for cardiac decompensation. Despite a confusing clinical presentation with gout symptoms, including repeated episodes of knee arthritis, persistent hypercalcemia conducted further investigations. Biological tests excluded primary or hyperparathyroidism and malignancy-related hyperparathyroidism, confirming the diagnosis of FHH through the detection of an inhibitory mutation in the calcium-sensing receptor gene.Conclusion: This case suggests to clinicians the possibility of FHH in older patients with unexplained hypercalcemia. In geriatric patients, the diagnosis is complicated because of the poly-pathology: here hypercalcemia was associated with a confusing gout crisis, which was triggered by diuretic treatment for heart failure.","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":"28 1","pages":"2436877"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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