Nutrition and Cancer-An International Journal最新文献_第3页

Exploring the Relationship Between Supplement Usage and Quality of Life Among Cancer Patients in Jordan: A Cross-Sectional Study. 探索约旦癌症患者补充剂使用与生活质量之间的关系：一项横断面研究。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2025-10-09 DOI: 10.1080/01635581.2025.2569903

Mohammad Alali, Suha Omran, Wafa'a Ta'an

{"title":"Exploring the Relationship Between Supplement Usage and Quality of Life Among Cancer Patients in Jordan: A Cross-Sectional Study.","authors":"Mohammad Alali, Suha Omran, Wafa'a Ta'an","doi":"10.1080/01635581.2025.2569903","DOIUrl":"10.1080/01635581.2025.2569903","url":null,"abstract":"This study explores the use of nutrition supplements by Jordanian cancer patients regarding symptoms of quality of life. It explores the prevalence of the use of nutrition supplements by cancer patients and the related demographic and disease-specific factors. A cross-sectional study was conducted on cancer patients at three major hospitals in Jordan. A total of 220 participants completed structured questionnaires. The EORTC QLQ-C15 scale was used to collect data on supplement usage patterns and quality of life. Chi-square tests and regression analysis were performed to assess the association between supplement use and QoL outcomes. Supplement use was noted in 65.9% of participants; the most used supplements were vitamin D, calcium, and omega-3. Supplement use was significantly associated with age, gender, income, and education level but showed a positive association between supplement use and improved QoL (p = 0.028). The findings suggest that the use of supplements is associated with improved quality of life among cancer patients in Jordan. It is important to consider integrating patient education and professional guidance regarding safe supplement use into cancer care. Further, longitudinal studies are needed to generalize these findings and to explore the long-term effect of supplements on QoL.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"70-79"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adherence to Oral Nutritional Support and Its Effect on Nutritional Status in Pediatric Oncology Patients. 坚持口服营养支持及其对儿科肿瘤患者营养状况的影响。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2025-12-07 DOI: 10.1080/01635581.2025.2584473

Mehmet Kantar, Derya Hopancı Bıçaklı, Ayşe Özkan, İnci İlhan, Nurdan Taçyıldız, Rejin Kebudi, Nurşah Eker, Zuhal Siviş, Uğur Demirsoy, Bahar Beker, Şule Yeşil, Ali Varan, Bengü Demirağ, İbrahim Bayram, Derya Özyörük, Eda Ataseven, Sonay İncesoy, Sema Büyükkapu, Burcu Tufan, Deniz Kızmazoğlu, Sema Vural, Burçak Kurucu, Çağrı Coşkun, Alihan Sürsal, Emre Özkan, Fatih Özdener

{"title":"Adherence to Oral Nutritional Support and Its Effect on Nutritional Status in Pediatric Oncology Patients.","authors":"Mehmet Kantar, Derya Hopancı Bıçaklı, Ayşe Özkan, İnci İlhan, Nurdan Taçyıldız, Rejin Kebudi, Nurşah Eker, Zuhal Siviş, Uğur Demirsoy, Bahar Beker, Şule Yeşil, Ali Varan, Bengü Demirağ, İbrahim Bayram, Derya Özyörük, Eda Ataseven, Sonay İncesoy, Sema Büyükkapu, Burcu Tufan, Deniz Kızmazoğlu, Sema Vural, Burçak Kurucu, Çağrı Coşkun, Alihan Sürsal, Emre Özkan, Fatih Özdener","doi":"10.1080/01635581.2025.2584473","DOIUrl":"10.1080/01635581.2025.2584473","url":null,"abstract":"Children with cancer frequently suffer from malnutrition caused by their disease and treatments. This study examines the rates of malnutrition, compliance with nutritional therapy, and its impact on nutritional status in pediatric cancer patients. This multicenter cross-sectional study was conducted between 2021 and 2023 at 12 pediatric hematology and oncology clinics. This study included 385 patients (aged 0.3-18 years) with leukemia-lymphoma and solid tumors that are currently on or had newly started oral nutritional supplement (ONS) treatment. Anthropometric measurements, mid-upper-arm-circumference (MUAC), body mass index (BMI), weight-for-age (WFA), were collected, and malnutrition risk was evaluated by the nutrition screening tool for childhood cancer (SCAN). Baseline WFA-based malnutrition was 31.0%, increasing to 38.5%, while SCAN≥3 was 83.8% decreasing to 72.4% at the sixth month. Malnutrition risk was more common in sarcoma and central nervous system tumor patients. ONS adherence decreased across all cancer types during the follow-up period. Adherent patients demonstrated higher BMI scores during the study period and MUAC z-scores in the last 2 months compared to the non-adherent group (P < 0.04). Our study demonstrates that the use of validated nutrition screening tools, together with adherence strategies, can lead to increased weight-for-age and lower malnutrition risk screening scores.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"145-157"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145702886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mountain-Cultivated Ginseng in Combination with Acupuncture Inhibits Breast Cancer Growth via PD-1/PD-L1 Degradation Mediated by AMPK-Induced Autophagy. 山参联合针刺通过ampk诱导的自噬介导PD-1/PD-L1降解抑制乳腺癌生长

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2026-02-03 DOI: 10.1080/01635581.2026.2621512

Xiaoru Xu, Shasha Fan, Mengqi Yang, Run Yuan, Dongyang Chen, Xin Chen, Ke Xiang, Nan Wang, Jianxun Zhu

{"title":"Mountain-Cultivated Ginseng in Combination with Acupuncture Inhibits Breast Cancer Growth via PD-1/PD-L1 Degradation Mediated by AMPK-Induced Autophagy.","authors":"Xiaoru Xu, Shasha Fan, Mengqi Yang, Run Yuan, Dongyang Chen, Xin Chen, Ke Xiang, Nan Wang, Jianxun Zhu","doi":"10.1080/01635581.2026.2621512","DOIUrl":"10.1080/01635581.2026.2621512","url":null,"abstract":"Immunotherapy has recently garnered more attention in the treatment of breast cancer. Ginseng has been extensively utilized in immunomodulation. Acupuncture is acknowledged as an effective adjunctive therapy for treating various cancers through the modulation of the immune system. Nonetheless, the extent to which the combination of ginseng and acupuncture exerts an enhanced anti-tumor effect in breast cancer treatment remains unclear. This study assessed the impact of mountain-cultivated ginseng in conjunction with acupuncture on the anti-tumor immune response in breast cancer in a 4T1 xenograft BALB/c mouse model. The findings indicated acupuncture, when paired with mountain-cultivated ginseng, could augment the suppression of tumor growth. Acupuncture in conjunction with ginseng therapy enhanced the immunological activity of CD8+ cytotoxic T cells by elevating the numbers of IFN-γ+/CD8+ T cells and TNF-α+/CD8+ T cells, along with the release of many pro-inflammatory cytokines (IL-2, IL-6, TNF-α, and IFN-γ). Furthermore, it was established that acupuncture in conjunction with ginseng therapy facilitated the degradation of PD-L1 and PD-1 via the Sirt1/AMPK-mediated autophagy pathway. This study revealed that the combination of acupuncture and ginseng treatment augmented the suppression of PD-1/PD-L1 immune checkpoint, hence amplifying the anti-tumor immune response and offering a potential method for breast cancer therapy.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"329-342"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on Impact of Sarcopenia and Osteopenia on Prognosis in Metastatic Biliary Tract Cancer: A Single Center Experience. 转移性胆道癌骨骼肌减少和骨质减少对预后的影响：单中心经验。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2026-03-26 DOI: 10.1080/01635581.2025.2598927

Jun Wang, Liqin Han, Zhimin He, Qiuyun Zhu

引用次数: 0

Letter to the Editor: Revisiting the Impact of Obesity on Cancer-Specific Survival in Rectal Cancer-Clinical and Translational Implications. 致编辑的信：重新审视肥胖对直肠癌癌症特异性生存的影响——临床和转化意义。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2025-11-17 DOI: 10.1080/01635581.2025.2584453

Pengyu Han, Jin Zhang, Xingyu Zhou, Donghu Liu, Jin Zheng

引用次数: 0

Letter to the Editor: Reevaluating Diet-microbiota Interactions in Colorectal Carcinogenesis. 致编辑的信：重新评估饮食-微生物群在结直肠癌发生中的相互作用。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2025-11-21 DOI: 10.1080/01635581.2025.2593434

Pınar Peker, Seher Selvi

引用次数: 0

Nutritional and Immune State of Gastric Cancer Patients Deteriorate During the Preoperative Period. 胃癌患者术前营养和免疫状况恶化

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2026-02-26 DOI: 10.1080/01635581.2026.2635081

Ryohei Nishiguchi, Shinichi Asaka, Takebumi Usui, Hajime Yokomizo, Shunichi Shiozawa, Andrew J Dannenberg

{"title":"Nutritional and Immune State of Gastric Cancer Patients Deteriorate During the Preoperative Period.","authors":"Ryohei Nishiguchi, Shinichi Asaka, Takebumi Usui, Hajime Yokomizo, Shunichi Shiozawa, Andrew J Dannenberg","doi":"10.1080/01635581.2026.2635081","DOIUrl":"10.1080/01635581.2026.2635081","url":null,"abstract":"Gastric cancer (GC) patients are vulnerable to malnutrition due to abdominal discomfort, nausea, vomiting, and anorexia. The Prognostic Nutritional Index (PNI), which combines serum albumin and total lymphocyte count (TLC), has prognostic value for numerous malignancies including GC. GC patients who are malnourished have a higher incidence of surgical complications and worse long-term prognosis. Although the link between PNI and prognosis is well established, whether the PNI decreases while GC patients await surgery is unknown. The primary objective of this study of 124 GC patients was to determine whether the nutritional and immune status decreased during the preoperative period. Here we demonstrate that the PNI decreased due to reductions in both serum albumin and TLC (P < 0.001); the effects were greater in advanced vs. early-stage GC. Corresponding decreases in BMI were found (P < 0.001). Significant reductions in PNI occurred over time regardless of tumor location. Tumor diameter was positively associated with the magnitude of PNI decline (P < 0.01). Reductions in preoperative PNI/day were associated with worsening of progression-free survival (PFS) and overall survival (OS). Collectively, these results provide a strong rationale for future nutritional support studies that aim to attenuate the preoperative decline in PNI and improve outcomes of GC patients.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"295-308"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147291854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional and Lifestyle Interventions for Prostate Cancer Patients Undergoing Radiotherapy: A Systematic Review. 前列腺癌放疗患者的营养和生活方式干预：系统综述。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2026-03-03 DOI: 10.1080/01635581.2026.2637661

Yushu Han, Yangyang Gong, Weiwei Zhang, Yiyin Liang, Zhen Jia, Liying Yang, Huojun Zhang

{"title":"Nutritional and Lifestyle Interventions for Prostate Cancer Patients Undergoing Radiotherapy: A Systematic Review.","authors":"Yushu Han, Yangyang Gong, Weiwei Zhang, Yiyin Liang, Zhen Jia, Liying Yang, Huojun Zhang","doi":"10.1080/01635581.2026.2637661","DOIUrl":"10.1080/01635581.2026.2637661","url":null,"abstract":"Background: Radiotherapy for prostate cancer often leads to gastrointestinal toxicity, weight gain, fatigue, and reduced quality of life. Nutrition and lifestyle interventions are increasingly used in cancer care, yet evidence specific to men receiving radiotherapy remains limited.Methods: We systematically searched PubMed, Embase, Web of Science, and the Cochrane Library to June 2025 for studies evaluating nutrition and lifestyle interventions in adults undergoing radiotherapy for prostate cancer. Study quality was assessed using the Cochrane Risk of Bias tool, Newcastle-Ottawa Scale, and ROBINS-I.Results: Nineteen studies were included. In radiotherapy-specific trials, individualized nutrition interventions showed potential to attenuate weight gain and manage gastrointestinal symptoms, while restrictive dietary modifications alleviated bowel complaints but were associated with declines in energy intake and nutritional status. Tomato-juice supplementation increased lycopene levels without consistent clinical benefit. In mixed-modality cohorts, dietary modifications were associated with meaningful weight loss and favorable changes in triglycerides, HDL, and HbA1c. Comprehensive lifestyle programs improved psychological distress, urinary symptoms, and quality of life.Conclusions: Nutrition and lifestyle interventions show promising signals for improving weight control, symptoms, metabolic profiles, and quality of life during radiotherapy. Given the heterogeneity of evidence, more robust, radiotherapy-specific randomized trials with standardized endpoints are needed to confirm efficacy.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"279-294"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147349548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin K2 Supplementation and Clinical Outcomes in Hepatocellular Carcinoma Patients: A Meta-Analysis with Trial Sequential Analysis. 维生素K2补充和肝细胞癌患者的临床结果：一项试验序列分析的荟萃分析。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2025-12-13 DOI: 10.1080/01635581.2025.2600102

Francisco Cezar Aquino de Moraes, Vitor Kendi Tsuchiya Sano, Caroline R M Pereira, Jamile Cristine Marques Barros, Rommel Mario Rodríguez Burbano

{"title":"Vitamin K2 Supplementation and Clinical Outcomes in Hepatocellular Carcinoma Patients: A Meta-Analysis with Trial Sequential Analysis.","authors":"Francisco Cezar Aquino de Moraes, Vitor Kendi Tsuchiya Sano, Caroline R M Pereira, Jamile Cristine Marques Barros, Rommel Mario Rodríguez Burbano","doi":"10.1080/01635581.2025.2600102","DOIUrl":"10.1080/01635581.2025.2600102","url":null,"abstract":"Background and aims: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality globally. The potential benefits of vitamin K (VK) supplementation for patients with HCC remain unclear. This study aimed to evaluate the impact of VK supplementation on clinical outcomes in patients undergoing HCC treatment.Methods: A systematic search across Medline, Scopus, and Web of Science databases identified relevant studies. Pooled odds ratios (OR) with 95% confidence intervals (CI) assessed treatment group differences in binary outcomes. Heterogeneity was evaluated using I2 statistics. Analyses were performed using R (version 4.2.3).Results: Eleven studies encompassing 1,030 patients were included. VK supplementation significantly reduced disease recurrence (DR) compared to control at 1 year (OR 0.55, 95% CI 0.32-0.97; p = 0.039), 2 years (OR 0.52, 95% CI 0.35-0.77; p = 0.001), and 3 years (OR 0.41, 95% CI 0.25-0.67; p = 0.000). Additionally, VK supplementation significantly decreased mortality at 1 year (OR 0.20, 95% CI 0.07-0.60; p = 0.004), 2 years (OR 0.38, 95% CI 0.18-0.82; p = 0.014), and 3 years (OR 0.37, 95% CI 0.21-0.66; p = 0.001). Notably, no significant difference in adverse events was observed between VK and control groups (OR 3.56, 95% CI 0.06-198.66; p = 0.536).Conclusion: This study suggests substantial benefits associated with VK supplementation in HCC patients, particularly in reducing DR and mortality across one, two, and three years. Importantly, these improvements were achieved without a significant increase in adverse events, indicating good tolerability of VK supplementation in this population.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"208-220"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Relationship Between Sarcopenia, Nutritional Status, and Frailty in Older Patients with Cancer. 老年癌症患者肌肉减少症、营养状况和虚弱之间关系的评价。

IF 2.4 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2026-01-01 Epub Date: 2025-11-07 DOI: 10.1080/01635581.2025.2582236

Diğdem Doğan Akagündüz, Hilal Şahin, Baran Akagündüz

{"title":"Evaluation of the Relationship Between Sarcopenia, Nutritional Status, and Frailty in Older Patients with Cancer.","authors":"Diğdem Doğan Akagündüz, Hilal Şahin, Baran Akagündüz","doi":"10.1080/01635581.2025.2582236","DOIUrl":"10.1080/01635581.2025.2582236","url":null,"abstract":"Sarcopenia, malnutrition, and frailty frequently coexist in older adults with cancer, adversely affecting treatment tolerance, functional independence, and survival. While comprehensive geriatric assessment (CGA) is the gold standard for frailty evaluation, its resource-intensive nature limits routine use, and simple tools are needed. This cross-sectional study included 291 patients aged ≥70 years with histologically confirmed cancer, evaluated at a oncology outpatient clinic between January and November 2024. Sarcopenia was defined according to EWGSOP2 criteria: handgrip strength (HGS) and skeletal muscle index (SMI) by bioelectrical impedance analysis (BIA). Nutritional status was assessed with the Mini Nutritional Assessment-Short Form (MNA-SF), and frailty was defined as G8 ≤ 14. Additional measures included SARC-F, Mini-Mental State Examination (MMSE), and Geriatric Depression Scale. The median age was 74 years, and 53% were male. Possible sarcopenia was identified in 39.5%, confirmed sarcopenia in 33.7%, severe sarcopenia in 26.8%. Nutritional risk was observed in 66.7%, and frailty in 44.7%. Frailty correlated strongly with nutritional status and moderately with muscle strength and mass. In multivariable analysis, low HGS, low SMI, nutritional risk, and depression independently predicted frailty. ROC analysis showed, G8 with HGS and nutritional assessment improved predictive accuracy. These findings highlight that simple measures enhance frailty detection and may support personalized care.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"134-144"},"PeriodicalIF":2.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145472348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0