Quantitative Imaging in Medicine and Surgery最新文献

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Rapid patient-specific organ dose estimation in computed tomography scans via integration of radiomics features and neural networks. 通过整合放射组学特征和神经网络,在计算机断层扫描中快速估算患者特定器官的剂量。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-24-645
Wencheng Shao, Xin Lin, Ying Huang, Liangyong Qu, Weihai Zhuo, Haikuan Liu
{"title":"Rapid patient-specific organ dose estimation in computed tomography scans via integration of radiomics features and neural networks.","authors":"Wencheng Shao, Xin Lin, Ying Huang, Liangyong Qu, Weihai Zhuo, Haikuan Liu","doi":"10.21037/qims-24-645","DOIUrl":"10.21037/qims-24-645","url":null,"abstract":"<p><strong>Background: </strong>Computed tomography (CT) offers detailed cross-sectional images of internal anatomy for disease detection but carries a risk of solid cancer or blood malignancies due to exposure to X-ray radiation. This study aimed to develop a new method to quickly predict patient-specific organ doses from CT examinations by training neural networks (NNs) based on radiomics features.</p><p><strong>Methods: </strong>CT Digital Imaging and Communications in Medicine (DICOM) image data were exported to DeepViewer, a clinical autosegmentation software, to segment the regions of interest (ROIs) for patient organs. Radiomics feature extraction was performed based on the selected CT data and ROIs. Reference organ doses were computed using Monte Carlo (MC) simulations. Patient-specific organ doses were predicted by training a NN model based on radiomics features and reference doses. For the dose prediction performance, the relative root mean squared error (RRMSE), mean absolute percentage error (MAPE), and coefficient of determination (R<sup>2</sup>) were evaluated on the test sets. The robustness of the NN model was evaluated via the random rearrangement of patient samples in the training and test sets.</p><p><strong>Results: </strong>The maximal difference between the reference and predicted doses was less than 1 mGy for all investigated organs. The range of MAPE was 1.68% to 5.2% for head organs, 11.42% to 15.2% for chest organs, and 5.0% to 8.0% for abdominal organs; the maximal R<sup>2</sup> values were 0.93, 0.86, and 0.89 for the head, chest, and abdominal organs, respectively.</p><p><strong>Conclusions: </strong>The radiomics feature-based NN model can achieve accurate prediction of patient-specific organ doses at a high speed of less than 1 second using a single central processing unit, which supports its use as a user-friendly online clinical application.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7379-7391"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A method framework of semi-automatic knee bone segmentation and reconstruction from computed tomography (CT) images. 根据计算机断层扫描(CT)图像进行半自动膝关节骨骼分割和重建的方法框架。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-24-821
Ahsan Humayun, Mustafain Rehman, Bin Liu
{"title":"A method framework of semi-automatic knee bone segmentation and reconstruction from computed tomography (CT) images.","authors":"Ahsan Humayun, Mustafain Rehman, Bin Liu","doi":"10.21037/qims-24-821","DOIUrl":"10.21037/qims-24-821","url":null,"abstract":"<p><strong>Background: </strong>Accurate delineation of knee bone boundaries is crucial for computer-aided diagnosis (CAD) and effective treatment planning in knee diseases. Current methods often struggle with precise segmentation due to the knee joint's complexity, which includes intricate bone structures and overlapping soft tissues. These challenges are further complicated by variations in patient anatomy and image quality, highlighting the need for improved techniques. This paper presents a novel semi-automatic segmentation method for extracting knee bones from sequential computed tomography (CT) images.</p><p><strong>Methods: </strong>Our approach integrates the fuzzy C-means (FCM) algorithm with an adaptive region-based active contour model (ACM). Initially, the FCM algorithm assigns membership degrees to each voxel, distinguishing bone regions from surrounding soft tissues based on their likelihood of belonging to specific bone regions. Subsequently, the adaptive region-based ACM utilizes these membership degrees to guide the contour evolution and refine segmentation boundaries. To ensure clinical applicability, we further enhance our method using the marching cubes algorithm to reconstruct a three-dimensional (3D) model. We evaluated the method on six randomly selected knee joints.</p><p><strong>Results: </strong>We evaluated the method using quantitative metrics such as the Dice coefficient, sensitivity, specificity, and geometrical assessment. Our method achieved high Dice scores for the femur (98.95%), tibia (98.10%), and patella (97.14%), demonstrating superior accuracy. Remarkably low root mean square distance (RSD) values were obtained for the tibia and femur (0.5±0.14 mm) and patella (0.6±0.13 mm), indicating precise segmentation.</p><p><strong>Conclusions: </strong>The proposed method offers significant advancements in CAD systems for knee pathologies. Our approach demonstrates superior performance in achieving precise and accurate segmentation of knee bones, providing valuable insights for anatomical analysis, surgical planning, and patient-specific prostheses.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7151-7175"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognition mediates the relationship between white matter hyperintensity and motor function in patients with cerebral small vessel disease: a cross-sectional study. 认知介导脑小血管疾病患者白质高密度与运动功能之间的关系:一项横断面研究。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-19 DOI: 10.21037/qims-24-1058
Xueyang Zhao, Mengyun Zuo, Fufang Zhan, Ping Fan, Sanxin Liu, Marcus Taylor, Mario Ganau, Walter A Hall, Hengfang Ruan, Lihong Wan
{"title":"Cognition mediates the relationship between white matter hyperintensity and motor function in patients with cerebral small vessel disease: a cross-sectional study.","authors":"Xueyang Zhao, Mengyun Zuo, Fufang Zhan, Ping Fan, Sanxin Liu, Marcus Taylor, Mario Ganau, Walter A Hall, Hengfang Ruan, Lihong Wan","doi":"10.21037/qims-24-1058","DOIUrl":"10.21037/qims-24-1058","url":null,"abstract":"<p><strong>Background: </strong>White matter hyperintensity (WMH) is a common neuroimaging marker of cerebral small vessel disease (SVD) and a critical independent predictor of motor dysfunction, which increases the risk of disability, morbidity, and mortality. However, the mechanism underlying the relationship between WMH and motor function has not yet been fully clarified. It was hypothesized that cognitive impairment mediates the relationship between WMH and motor dysfunction in patients with SVD, which were considered predictor and outcome variables, respectively.</p><p><strong>Methods: </strong>A total of 221 patients with SVD were enrolled in this study, and their magnetic resonance imaging (MRI), neuropsychological, and motor function data were collected. The MRI data were visually assessed to determine the WMH burden using the Fazekas scale. Cognition was evaluated using the Montreal Cognitive Assessment (MoCA). Motor function was assessed using the Tinetti Gait and Balance Scale and the Short Physical Performance Battery (SPPB). Finally, a bootstrap analysis was performed to determine whether cognition mediated the relationship between WMH and motor function.</p><p><strong>Results: </strong>Of all the patients, 30.3% had mild WMH, 37.6% had moderate WMH, and 32.1% had severe WMH. Patients' cognition and motor function decreased as the WMH burden increased (P<0.01). The MoCA scores were associated with the Tinetti scale (r=0.545, P<0.01) and SPPB scores (r=0.365, P<0.01). Finally, multi-categorical mediation models confirmed our research hypothesis; the coefficients for the indirect effects had 95% confidence intervals (CIs) that excluded zero, indicating statistically significant mediation effects.</p><p><strong>Conclusions: </strong>WMH is associated with motor dysfunction, and this association is mediated by cognition in patients with SVD. This finding highlights the importance of early interventions targeting cognitive function to reduce the risk of motor dysfunction.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7306-7317"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of computer-aided quantitative measurement and physician visual assessment in the evaluation of intracranial atherosclerotic stenosis: a vessel wall magnetic resonance imaging study. 计算机辅助定量测量与医生目测评估在颅内动脉粥样硬化狭窄评估中的比较:血管壁磁共振成像研究。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-24-788
Ying Du, Lingling Sun, Yilin Wang, Fangbing Li, Tianxiang Hu, Yejun Wu
{"title":"Comparison of computer-aided quantitative measurement and physician visual assessment in the evaluation of intracranial atherosclerotic stenosis: a vessel wall magnetic resonance imaging study.","authors":"Ying Du, Lingling Sun, Yilin Wang, Fangbing Li, Tianxiang Hu, Yejun Wu","doi":"10.21037/qims-24-788","DOIUrl":"10.21037/qims-24-788","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Intracranial atherosclerotic stenosis is a leading cause of ischemic stroke in China. Accurate assessment of intracranial atherosclerotic stenosis through imaging techniques is crucial for guiding therapeutic interventions and prognostic stratification. Vessel wall magnetic resonance imaging (VWMRI) has emerged as a reliable method for evaluating intracranial arterial vessels. With the advancement of technology, computer-aided quantitative measurement (CAQM) is increasingly used in imaging assessment. This study aimed to compare physician visual assessment (PVA) with CAQM in the VWMRI evaluation of intracranial atherosclerotic stenosis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective cross-sectional study consecutively enrolled patients diagnosed with intracranial atherosclerotic stenosis through imaging examinations at the Fourth Affiliated Hospital of China Medical University from December 2018 to December 2023. Clinical data were collected for analysis. Two radiologists independently and separately conducted CAQM and PVA on the VWMRI images of intracranial atherosclerotic stenosis patients. The imaging features evaluated encompassed stenosis severity, vessel wall remodeling, vessel wall thickening patterns, fibrous cap characteristics, lipid core ratio, and plaque enhancement degree. The study further assessed the discrepancies and concordance between the assessment results obtained from the two methods using paired sample t-tests, Wilcoxon signed-rank tests, and Cohen's kappa coefficient analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;This study enrolled a total of 589 patients. The PVA time was shorter than CAQM (12.02±3.63 &lt;i&gt;vs&lt;/i&gt;. 20.48±6.50 min). However, compared with digital subtraction angiography, the CAQM had a better area under the curve (0.88) than the PVA (0.80) in assessing luminal stenosis degree. The proportions of vessel wall remodeling (227/38.5%) and plaque surface irregularity (127/21.6%) evaluated by PVA were both lower than those by CAQM (438/74.4%, 171/29.0%). Meanwhile, no statistically significant differences were found in the patterns of wall thickening (P=0.12/0.39) and the proportion of plaque lipid core (P=0.65 and P=0.27), with good agreement between the two methods (K=0.67/0.85, K=0.97/0.94). While there were no statistical differences in the assessment of plaque enhancement degree in specific arteries (middle cerebral artery and basilar artery) (n=77/36, P=0.08/0.21), an overall statistical difference was observed (n=113, P=0.03). Additionally, there was poor agreement in assessing plaque enhancement degree, with Cohen's kappa values of 0.13 (-0.05 to 0.32) and 0.16 (-0.06 to 0.39).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study revealed disparities between PVA and CAQM in the evaluation of intracranial atherosclerotic stenosis of VWMRI. CAQM is recommended for assessing stenosis degree, vessel wall remodeling, and fibrous cap characteristics. However, PVA is suggested to assess wa","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7459-7471"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transesophageal echocardiography-based diagnosis of aortic dissection with intimal tear prolapsing components of the lamella into the left ventricle: a case description. 基于经食管超声心动图的主动脉夹层诊断,内膜撕裂使薄层成分脱垂至左心室:病例描述。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-24-807
Chao Xu, Nianyu Xue
{"title":"Transesophageal echocardiography-based diagnosis of aortic dissection with intimal tear prolapsing components of the lamella into the left ventricle: a case description.","authors":"Chao Xu, Nianyu Xue","doi":"10.21037/qims-24-807","DOIUrl":"10.21037/qims-24-807","url":null,"abstract":"","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7764-7767"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of three-dimensional (3D) magnetic resonance (MR) Multi-Echo iN Steady-state Acquisition sequences in preoperative evaluation of lumbar disc herniation: a prospective study. 三维(3D)磁共振(MR)多回波 iN 稳态采集序列在腰椎间盘突出症术前评估中的应用:一项前瞻性研究。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-13 DOI: 10.21037/qims-23-1834
Xuelin Pan, Yuting Wen, Kangkang Huang, Jing Li, Wanjiang Li, Weijie Yan, Deying Wen, Miaoqi Zhang, Shangxian Wang, Xinyi Zhang, Zhenlin Li, Xin Rong
{"title":"Application of three-dimensional (3D) magnetic resonance (MR) Multi-Echo iN Steady-state Acquisition sequences in preoperative evaluation of lumbar disc herniation: a prospective study.","authors":"Xuelin Pan, Yuting Wen, Kangkang Huang, Jing Li, Wanjiang Li, Weijie Yan, Deying Wen, Miaoqi Zhang, Shangxian Wang, Xinyi Zhang, Zhenlin Li, Xin Rong","doi":"10.21037/qims-23-1834","DOIUrl":"10.21037/qims-23-1834","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Conventional spinal magnetic resonance imaging (MRI) cannot provide accurate diagnosis and surgical planning; thin-layer scanning can enhance the diagnostic efficacy. This study aimed to investigate the value of 3-dimensional (3D) magnetic resonance (MR) in preoperative evaluation of lumbar disc herniation, with a focus on the application of Multi-Echo iN Steady-state Acquisition (MENSA) sequence.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 51 patients who underwent lumbar disc herniation surgery in West China Hospital of Sichuan University from June 2021 to December 2021 were prospectively enrolled. A cross-sectional study was conducted on those patients. The Cube group was scanned using 3D-FSE-Cube sequence, the Cube stir group was scanned using 3D-FSE-Cube Short Tau Inversion Recovery (STIR) sequence, and the MENSA group was scanned using MENSA sequence. Signal and noise values of nerve, herniated disc, ligamentum flavum (LF), and soft tissue were measured on the 3 groups. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Objective scores were calculated by analysis of variance (ANOVA). Image quality was scored by a 5-point method. Friedman test was used to compare subjective scores, and Kappa test was used to evaluate the consistency of 2 readers' scores.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The nerve root SNRs in the MENSA and Cube stir groups were higher than that in the Cube group (P&lt;0.01), but there was no substantial statistical difference between the 2 groups. The herniated disc and LF SNRs of the MENSA group were greater than those of the Cube stir and Cube groups (P&lt;0.01). Soft tissue SNR was greater in the MENSA group compared with the Cube stir group (P&lt;0.01), which was greater than the SNR in the Cube group (P&lt;0.01). The nerve root CNR of the Cube group (102.88±73.19) was greater than that of the MENSA group (55.98±25.26, P&lt;0.01), which was higher than the CNR in the Cube Stir group (29.42±16.22, P&lt;0.01). The herniated disc CNR was higher in the MENSA and Cube groups than that in the Cube Stir group. The CNR of LF was greater in the MENSA group (37.71±16.87) compared to the Cube group (29.76±25.73, P=0.03), which was greater than that in the Cube stir group (10.50±7.75, P&lt;0.01). Among the subjective ratings of 2 reviewers, MENSA sequence scored highest in the qualitative measures of image quality. In the consistency test, the Kappa values of 2 readers for 3 groups of images were all greater than 0.73, indicating good consistency. The differences of subjective scores among all groups were statistically significant (P&lt;0.05). Overall, it was indicated that the consistency test results of the 2 readers were statistically significant and consistent. The MENSA group had the highest accuracy in diagnosing nerve compression. In addition, MENSA sequence ranked highest among the 3 sequences with 94.1% diagnostic accuracy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The preoperative 3D MRI MENSA ","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7540-7550"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic value of a magnetic resonance imaging (MRI)-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis. 基于磁共振成像(MRI)的脊椎骨质量评分对骨矿物质密度评估的诊断价值:最新系统综述和荟萃分析。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-24-532
Dandan Yang, Chuan Liu, Qiaojun Hu
{"title":"Diagnostic value of a magnetic resonance imaging (MRI)-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis.","authors":"Dandan Yang, Chuan Liu, Qiaojun Hu","doi":"10.21037/qims-24-532","DOIUrl":"10.21037/qims-24-532","url":null,"abstract":"<p><strong>Background: </strong>Many studies have explored the application of the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score as a tool for opportunistic osteoporosis screening before spine surgery. We aimed to conduct a systematic review and meta-analysis of studies to determine the diagnostic value of the VBQ score for bone mineral density (BMD) assessment.</p><p><strong>Methods: </strong>The PubMed, EBSCO, Ovid, Web of Science, Cochrane Library, Wanfang, China National Knowledge Infrastructure, Chinese Science and Technology Periodical databases were searched to retrieve original studies on VBQ and BMD published from inception to 31 December 2023 with no restrictions on language and the reference standard of BMD. The quality of the included articles was assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2). Summary accuracy metrics were obtained by bivariate random-effects meta-analysis. The area under the curve (AUC) of the summary receiver operating characteristic (SROC) analysis was used to evaluate the performance of the VBQ score. Meta-regression and subgroup analyses were performed to examine the source of heterogeneity.</p><p><strong>Results: </strong>In total, 23 studies, comprising 2981 patients, from 2022 to 2023, of high- or medium-to-high scientific quality were included in the meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratio (DOR) of the VBQ score in the assessment of BMD were 0.77 [95% confidence interval (CI), 0.73-0.81; P<0.001], 0.65 (95% CI, 0.59-0.71; P<0.001), and 6.49 (95% CI, 4.82-8.73; P<0.001), respectively, with an area under the SROC curve of 0.78 (95% CI, 0.74-0.82; P<0.001). The presence of heterogeneity was found to have a significant association with factors such as the reference standard, sex, mean age, region of publication, VBQ method, and magnet field strength.</p><p><strong>Conclusions: </strong>The MRI-based VBQ score has some diagnostic value in detecting osteoporosis. The VBQ score could be used as a tool for opportunistic osteoporosis screening before spine surgery.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7561-7575"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of quantitative T1 mapping to serve as a novel prognostic predictor of clear cell renal cell carcinoma after nephrectomy. 定量 T1 图谱作为肾切除术后透明细胞肾细胞癌的新型预后预测指标的潜力。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-23-1829
Lianting Zhong, Ruiting Wang, Qiying Tang, Shunfa Huang, Chenchen Dai, Yuqin Ding, Jianjun Zhou
{"title":"Potential of quantitative T1 mapping to serve as a novel prognostic predictor of clear cell renal cell carcinoma after nephrectomy.","authors":"Lianting Zhong, Ruiting Wang, Qiying Tang, Shunfa Huang, Chenchen Dai, Yuqin Ding, Jianjun Zhou","doi":"10.21037/qims-23-1829","DOIUrl":"10.21037/qims-23-1829","url":null,"abstract":"<p><strong>Background: </strong>Accurate preoperative risk stratification methods are important for clear cell renal cell carcinoma (ccRCC) patients to enable personalized treatment. However, there are still no accurate and quantitative prognostic factors. This study aimed to investigate the effectiveness of T1 mapping in predicting the progression-free survival (PFS) of ccRCC after nephrectomy.</p><p><strong>Methods: </strong>A retrospective cohort study was performed in a China tertiary care hospital. This study reviewed the clinical and magnetic resonance imaging (MRI) data of consecutive inpatients with pathologically confirmed ccRCCs between September 2014 and September 2021. PFS was evaluated by following patients until the first adverse event. Radiological features including T1 relaxation time of tumors were assessed by 2 radiologists. Cox regression and visual nomogram, Kaplan-Meier survival, and log-rank test were utilized for survival analysis.</p><p><strong>Results: </strong>A total of 195 patients with pathologically confirmed ccRCCs (mean age ± standard deviation, 56.0±12.0 years; 133 men) with eligible data were included in the study. The median follow-up was 27.6 months (range, 1-88 months), and 22 (11.3%) patients experienced metastasis or recurrence. Univariate and multivariate survival analysis showed the higher post-contrasted T1 relaxation time [P=0.001; hazard ratio (HR), 2.077; 95% confidence interval (CI): 1.350-3.196] and the incomplete tumor capsule (P<0.001; HR, 7.849; CI: 2.614-23.570) were independently associated with a shorter PFS of patients. Patients with ≥222.73 ms post-contrasted T1 relaxation time ccRCCs had worse PFS than the lower post-contrasted T1 relaxation time group.</p><p><strong>Conclusions: </strong>The T1 mapping quantitative parameters may be a new potential biomarker for predicting PFS in patients with ccRCCs.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7600-7611"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics, treatment, and outcomes of spontaneous renal artery dissection: a 10-year retrospective single-center experience. 自发性肾动脉夹层的特征、治疗和结果:10 年单一中心的回顾性经验。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI: 10.21037/qims-24-994
Xinzhi Yang, Pengyu Li, Bihui Zhang, Ziguang Yan, Guochen Niu, Min Yang
{"title":"Characteristics, treatment, and outcomes of spontaneous renal artery dissection: a 10-year retrospective single-center experience.","authors":"Xinzhi Yang, Pengyu Li, Bihui Zhang, Ziguang Yan, Guochen Niu, Min Yang","doi":"10.21037/qims-24-994","DOIUrl":"10.21037/qims-24-994","url":null,"abstract":"<p><strong>Background: </strong>Spontaneous renal artery dissection (SRAD) is a rare cause of renal failure and renovascular hypertension, with the diagnosis often being delayed and treatment varying across different centers. The objective of this retrospective cohort study was to scrutinize the characteristics, treatment modalities, and outcomes of patients with SRAD at our center over the past ten years. Furthermore, the study sought to identify the most suitable treatment options for different categories of patients with SRAD.</p><p><strong>Methods: </strong>Data from 21 consecutive patients who presented with symptoms of SRAD from December 2013 to December 2023 were collected. Lesion characteristics, treatment options, blood pressure (BP) control, serum creatinine and estimated glomerular filtration rate (eGFR) were analyzed. A paired <i>t</i>-test was used for comparisons of BP, serum creatinine, and eGFR. An independent samples <i>t</i>-test was used to analyze baseline BP and BP change in different treatment groups.</p><p><strong>Results: </strong>The mean age, weight, and height of patients with SRAD was 49.2±13.0 (range, 18-69) years, 69.0±9.7 (range, 50-80) kg, and 1.7±0.1 (range 1.6-1.8) m, respectively. New-onset hypertension was found in 8 (38.1%) patients. Renal artery dissecting aneurysm and renal artery stenosis were found in 1 (4.8%) and 4 (19.0%) patients, respectively. Supportive medical treatment alone, endovascular intervention, and nephrectomy were required in 15, 4 and 2 cases, respectively. Stable renal function and satisfactory hypertension control were obtained in all treatment groups, with a median follow-up of 18.1 (range, 12-32) months.</p><p><strong>Conclusions: </strong>Medical management is a reasonable choice in most patients with SRAD. Interventional management is an efficacious strategy for the management of renovascular hypertension and the preservation of renal function.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7433-7441"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination of cardiac magnetic resonance with troponin to facilitate the earliest reversible stage of diagnosis and intervention of cancer therapy-related cardiac dysfunction: a description of three cases. 心脏磁共振与肌钙蛋白相结合,促进癌症治疗相关心功能障碍的最早可逆阶段诊断和干预:三个病例的描述。
IF 2.9 2区 医学
Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-13 DOI: 10.21037/qims-24-910
Yong Zhang, An-Qi Lyu, Fang Zhang, Ling-Di Zhao, Hong-Kai Zhang, Zi-Bing Wang, Tie-Peng Li, Wen-Jing Wang, Fang-Hui Li, Hong-Qin You, Quan-Li Gao, Jin-Rong Qu
{"title":"Combination of cardiac magnetic resonance with troponin to facilitate the earliest reversible stage of diagnosis and intervention of cancer therapy-related cardiac dysfunction: a description of three cases.","authors":"Yong Zhang, An-Qi Lyu, Fang Zhang, Ling-Di Zhao, Hong-Kai Zhang, Zi-Bing Wang, Tie-Peng Li, Wen-Jing Wang, Fang-Hui Li, Hong-Qin You, Quan-Li Gao, Jin-Rong Qu","doi":"10.21037/qims-24-910","DOIUrl":"10.21037/qims-24-910","url":null,"abstract":"","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":"14 10","pages":"7717-7722"},"PeriodicalIF":2.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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