Fukang Zhang, Huayu You, Yanlan Deng, Guiquan Chen, Yihui Qiu, Zhiyong Ling, Huasong Cai, Nan Liu
{"title":"MDCT-Based Grading of Perirenal Changes Secondary to Acute Unilateral Upper Urinary Tract Obstruction.","authors":"Fukang Zhang, Huayu You, Yanlan Deng, Guiquan Chen, Yihui Qiu, Zhiyong Ling, Huasong Cai, Nan Liu","doi":"10.2174/0115734056329112250710123850","DOIUrl":"https://doi.org/10.2174/0115734056329112250710123850","url":null,"abstract":"<p><strong>Background: </strong>Unilateral upper ureteral obstruction is one of the most common causes of acute kidney function impairment. Grading perirenal changes secondary to acute unilateral upper urinary tract obstruction (AUUTO) with multidetector spiral computed tomography (MDCT) and exploring its association with kidney function are useful for diagnosing and assessing damage to the ipsilateral kidney. However, the correlation between renal function impairment and the severity of perinephric changes secondary to AUUTO has not been reported.</p><p><strong>Objective: </strong>This study aimed to investigate the association of perirenal changes secondary to AUUTO with hydronephrosis and serum creatinine levels, as well as white blood cell counts.</p><p><strong>Methods: </strong>This retrospective study included 376 patients with acute unilateral upper ureteral obstruction, all of whom were subjected to MDCT scans. They were classified into four grades (0-III) according to their perirenal changes on MDCT images. The severity of hydronephrosis was classified into four grades based on MDCT scans. The serum creatinine level and leukocyte counts were compared among the MDCT grade groups, and logistic regression analysis was conducted.</p><p><strong>Results: </strong>Among 376 patients, 77 (20.5%), 103 (27.4%), 140 (37.2%), and 56 (14.9%) cases were graded into MDCT 0, I, II, and III, respectively. The proportions of patients who had normal kidneys in MDCT 0, I, II, and III were 20 (26.0%), 10 (9.7%), 11(7.9%), and 3 (5.4%), respectively. The proportions of patients who had mild hydronephrosis in MDCT 0, I, II, and III were 55 (71.4%), 83 (80.6%), 118 (84.2%), and 46 (82.1%), respectively. The proportions of patients who had moderate and severe hydronephrosis in MDCT 0, I, II, and III were 2(2.6%), 10 (9.7%), 11 (7.9%), 7 (12.5%), respectively. Serum creatinine levels and white blood cell counts were significantly different among the MDCT grade groups (P < 0.001). Univariate and multivariate logistic regression analyses indicated that the serum creatinine level and white blood cell counts were positively associated with the MDCT grades (P < 0.001).</p><p><strong>Conclusion: </strong>Perinephric changes secondary to AUUTO on MDCT images were associated with the degree of obstruction. The severity of perinephric changes can reflect the functional impairment in the ipsilateral kidney. The MDCT grades may aid clinicians in assessing renal function impairment early in patients with AUUTO, which may help patients receive early intervention and avoid the potential risk of infection and deterioration of renal function.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CT Features of Advanced Pericochlear Otosclerosis: Case Report and a Reappraisal of Nomenclature.","authors":"Rowa A Mohamed, Mohamed S Muneer, Tarik F Massoud","doi":"10.2174/0115734056379053250712052649","DOIUrl":"https://doi.org/10.2174/0115734056379053250712052649","url":null,"abstract":"<p><strong>Background: </strong>This case study aimed to report the rare computed tomography (CT) features of advanced pericochlear otosclerosis, with an emphasis on a proposed new nomenclature to describe the imaging findings.</p><p><strong>Case presentation: </strong>A 70-year-old woman with recurrent rhinosinusitis presented to our center for clinical management. The CT scan revealed the incidental rare findings of advanced retrofenestral otosclerosis in the form of extensive symmetrical pericochlear tubular lucencies in bilateral otic capsules. We coined the new term \"C-hoop earring\" sign for this CT appearance. She was asymptomatic and declined further audiological or imaging evaluation.</p><p><strong>Conclusion: </strong>Herein, the CT features of advanced pericochlear otosclerosis are described and the imaging and clinical connotations of the presence of the Choop earring sign are reviewed. This new terminology provides a more intuitive description of the imaging findings in the temporal bones for clearer understanding and communication in clinical radiological practice and education.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report on the Dramatic Response of <sup>177</sup>Lu-PSMA Therapy for Metastatic Prostate Cancer.","authors":"Aysenur Sinem Erdogan, Haluk Sayan, Bedri Seven, Berna Okudan","doi":"10.2174/0115734056362468250709045212","DOIUrl":"https://doi.org/10.2174/0115734056362468250709045212","url":null,"abstract":"<p><strong>Introduction: </strong>In nuclear medicine, Prostate-specific Membrane Antigen (PSMA) is a potential target for theranostics. Offering superior diagnostic accuracy to conventional imaging in prostate cancer (PCa), Gallium-68 labeled PSMA (<sup>68</sup>Ga-PSMA) positron emission tomography/computed tomography (PET/CT) is considered the new standard of care in PCa management. Tumor cells identified as PSMA-avid on PET/CT imaging can be targeted and eliminated with PSMA-labeled Lutetium-177 (<sup>177</sup>Lu-PSMA) therapy.</p><p><strong>Case presentation: </strong>A sixty-eight years old patient who had metastatic castration-resistant PCa was reported in this study. Prior to receiving <sup>177</sup>Lu-PSMA therapy, the patient's PSA level was 358 ng/ml, and experienced extensive bone discomfort. Following ten cycles of <sup>177</sup>Lu-PSMA therapy, exceptional results were observed.</p><p><strong>Conclusion: </strong><sup>177</sup>Lu-PSMA therapy is likely to result in significantly better outcomes if first- or second-line treatments preserve the patient's bone marrow reserve or if the therapy is administered at earlier stages of the disease.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaopeng Wang, Chaoyong Liu, Ruotong Mu, Yi Chen, Di Gong, Qiang Yang, Qiang Liu
{"title":"Translation of Fundus Image to Fundus Fluorescein Angiography Boosted by Structure Self-Supervised Representation Cycle Learning.","authors":"Xiaopeng Wang, Chaoyong Liu, Ruotong Mu, Yi Chen, Di Gong, Qiang Yang, Qiang Liu","doi":"10.2174/0115734056374967250704090646","DOIUrl":"https://doi.org/10.2174/0115734056374967250704090646","url":null,"abstract":"<p><strong>Introduction: </strong>Fundus fluorescein angiography captures detailed images of fundus vasculature, enabling precise disease assessment. Translating fundus images to fundus fluorescein angiography images can assist patients unable to use contrast agents due to physical constraints, facilitating disease analysis. Previous studies on this translation task were limited by the use of only 17 image pairs for training, potentially restricting model performance.</p><p><strong>Methods: </strong>Image pairs were collected from patients through a collaborating hospital to create a larger dataset. A fundus image to fundus fluorescein angiography translation model was developed using structure self-supervised representation cycle learning. This model focuses on vascular structures for self-supervised learning, incorporates an auxiliary branch, and utilizes cycle learning to enhance the main training pipeline.</p><p><strong>Results: </strong>Comparative evaluations on the test set demonstrate superior performance of the proposed model, with significantly improved Fréchet inception distance and kernel inception distance scores. Additionally, generalization experiments conducted on public datasets further confirm the model's advantages in various evaluation metrics.</p><p><strong>Discussion: </strong>The enhanced performance of the proposed model can be attributed to the larger dataset and the novel structure self-supervised cycle learning approach, which effectively captures vascular details critical for accurate translation. The model's robust generalization across public datasets suggests its potential applicability in diverse clinical settings. However, challenges such as computational complexity and the need for further validation in real-world scenarios warrant additional investigation to ensure scalability and clinical reliability.</p><p><strong>Conclusion: </strong>The proposed model effectively translates fundus images to fundus fluorescein angiography images, overcoming limitations of small datasets in previous studies. This approach demonstrates strong generalization capabilities, highlighting its potential to aid in large-scale disease analysis and patient care.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Deep Learning Methods for Pulmonary Disease Classification.","authors":"Ajay Pal Singh, Ankita Nigam, Gaurav Garg","doi":"10.2174/0115734056388107250710120917","DOIUrl":"https://doi.org/10.2174/0115734056388107250710120917","url":null,"abstract":"<p><strong>Introduction: </strong>Driven by environmental pollution and the rise in infectious diseases, the increasing prevalence of lung conditions demands advancements in diagnostic techniques.</p><p><strong>Materials and methods: </strong>This study explores the use of various features, such as spectrograms, chromograms, and Mel Frequency Cepstral Coefficients (MFCC), to extract crucial information from auscultation recordings. It addresses challenges through filter-based audio enhancement methods. The primary goal is to improve disease detection accuracy by leveraging convolutional neural networks (CNNs) for feature extraction and dense neural networks for classification.</p><p><strong>Results: </strong>While deep learning models like CNNs and Recurrent Neural Network (RNN) outperform traditional machine learning models such as Sequence Vector Machine, K-Nearest Neighbours (KNN) and random forest with accuracies ranging from 70% to 85%. The combination of CNN, RNN, and long short-term memory achieved an accuracy of 88%. By integrating MFCC, Chroma Short-Term Fourier Transform (STFT), and spectrogram features with a CNN-based classifier, the proposed multi-feature deep learning model achieved the highest accuracy of 92%, surpassing all other methods.</p><p><strong>Discussion: </strong>The study effectively addresses key issues, including the overrepresentation of Chronic Obstructive Pulmonary Disease (COPD) samples over Lower Respiratory Tract Infections (LRTI) and Upper Respiratory Tract Infections (URTI) which hampers generalization across test audio samples.</p><p><strong>Conclusion: </strong>The proposed methodology caters common challenges like background noise in recordings, and the limited and imbalanced nature of datasets. These findings pave the way for enhanced clinical applications, showcasing the transformative potential of multi-feature deep learning methods in the classification of pulmonary diseases.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeonhee Lee, Sowon Jang, Minseon Kim, Junghoon Kim
{"title":"Diagnostic Efficacy of PET/CT-Aided <i>versus</i> Conventional CT-guided Lung Biopsy: A Systematic Review and Meta-Analysis.","authors":"Yeonhee Lee, Sowon Jang, Minseon Kim, Junghoon Kim","doi":"10.2174/0115734056394487250702094607","DOIUrl":"https://doi.org/10.2174/0115734056394487250702094607","url":null,"abstract":"<p><strong>Introduction: </strong>Unlike its well-established role in lung cancer staging, positron emission tomography /computed tomography (PET/CT)'s role in guiding lung biopsies remains unclear and underutilized, despite its potential to distinguish metabolically active regions from areas of necrosis or fibrosis within lesions.</p><p><strong>Objective: </strong>This study aims to assess the diagnostic efficacy of PET/CT-aided <i>versus</i> conventional CT-guided lung biopsy by comparing the incidences of non-diagnostic results, false results, and complications.</p><p><strong>Methods: </strong>Studies comparing PET/CT-aided and conventional CT-guided lung biopsy were identified through an intensive search of PubMed, Embase, and the Cochrane Library. Data on nondiagnostic results, false results, and complications were extracted. Risk ratios (RRs) with 95% confidence intervals (CIs) were calculated using a random-effects model.</p><p><strong>Results: </strong>Seven studies involving 1,661 procedures were included. PET/CT-aided lung biopsy significantly reduced nondiagnostic results compared to conventional CT-guided biopsy (2.8% vs. 9.1%; pooled RR: 0.38, 95% CI: 0.20-0.70, P = 0.002). False results were also significantly fewer in the PET/CT-aided group (6.5% vs. 17.0%; pooled RR: 0.48, 95% CI: 0.35-0.65, P < 0.001). There was no statistically significant difference in overall complication rates (28.1% vs. 32.5%; pooled RR: 0.92, 95% CI: 0.77-1.10, P = 0.352), while PET/CT-aided biopsy showed a slight tendency toward fewer major complications (0.9% vs. 1.7%; pooled RR: 0.67, 95% CI: 0.30-1.44, P = 0.303).</p><p><strong>Conclusion: </strong>PET/CT-aided CT-guided lung biopsy offers advantages over conventional CT-guided lung biopsy by significantly reducing nondiagnostic and false results, without significant differences in the risk of complications.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Noninvasive Evaluation of the Rat Adenomyosis Model Constructed by Autologous Endometrial Implantation Using Magnetic Resonance Imaging.","authors":"Qi Zhang, Qianwen Zhu, Linghui Xu, Yujia Shen, Junhai Zhang","doi":"10.2174/0115734056375955250703115947","DOIUrl":"https://doi.org/10.2174/0115734056375955250703115947","url":null,"abstract":"<p><strong>Introduction: </strong>Dynamic changes in adenomyotic lesions in animal models have been difficult to observe and evaluate in vivo on a regular basis. Therefore, this study aims to investigate the feasibility of establishing a rat model of adenomyosis through autologous endometrial implantation and to assess the value of magnetic resonance imaging (MRI) for noninvasive evaluation of the model.</p><p><strong>Methods: </strong>Forty rats were randomly divided into two groups (20 rats in the control group, 20 rats in the model group). A rat adenomyosis model was constructed through autologous endometrial implantation. Three months after the modeling surgery, the rats underwent MRI examination, including T2-weighted axial imaging and T1-weighted axial imaging. The thickness of the uterine myometrium and junctional zone was measured. Following the MRI, the rat uterus was sliced for hematoxylin-eosin (HE) staining.</p><p><strong>Results: </strong>In the model group, lesions of adenomyosis were successfully established in all surviving rats. The myometrium of the rat uterus showed uneven thickening accompanied by scattered spotty T2 hypersignal. The junctional zone appeared as a low-signal band between the endometrium with high signal and the myometrium. The average thicknesses of both the myometrium and the junctional zone were significantly greater in the model group compared to the control group, with the differences reaching statistical significance. Ectopic endometrium can lead to hyperplasia of the peripheral muscle cells in the myometrium, which is manifested on T2-weighted images as localized thickening and hypo-intensity of the myometrium interspersed with punctiform hyperintensity. Histologically, regions of low signal intensity refer to hyperplasia of smooth muscle, while bright foci on T2-weighted images correspond to ectopic endometrial tissue and cystic dilation of glands. This study proved the noninvasive evaluation of a rat adenomyosis model and described the junctional zone in rats using MRI techniques. Histological examination using HE staining confirmed a higher nuclear-to-cytoplasmic ratio and a more compact cell arrangement in the junctional zone region of rats compared to the outer myometrium, which could explain its hypointensity.</p><p><strong>Conclusion: </strong>MRI is a valuable method for evaluating the rat adenomyosis model non-invasively. Furthermore, the successful visualization of the junctional zone in the rat uterus using MRI may have potential applications in further evaluating the progression of adenomyosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-Invasive Assessment of Rheumatoid Arthritis Cardiac Involvement: A Systematic Review of Echocardiography.","authors":"Huang Xingxing, Chen Tianyi, Yu Xiaolong","doi":"10.2174/0115734056375528250701165335","DOIUrl":"https://doi.org/10.2174/0115734056375528250701165335","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is a systemic autoimmune disorder primarily characterized by joint degradation, with consequential cardiovascular ramifications significantly impacting patient mortality rates.</p><p><strong>Methods: </strong>We systematically searched for full-text English-language journal articles from 1973 to 2025 in the PubMed and Web of Science databases. Utilizing keywords such as \"Rheumatoid Arthritis,\" \"Autoimmune Diseases,\" \"Pathophysiology,\" \"Heart,\" \"Cardiac,\" and \"Echocardiography\" to narrow the search results. Articles related to the evaluation of heart diseases in rheumatoid arthritis by echocardiography were included, while those with insufficient data or low data quality were excluded. Study quality was assessed using the CASP Quantitative Checklist (2018 version), and data were synthesized through thematic content analysis.</p><p><strong>Results: </strong>We included 52 studies in this review after the primary analysis. The results show that traditional echocardiography can identify organic changes in the heart and ventricular function impairment of patients with rheumatoid arthritis. New ultrasound techniques, such as speckle tracking and pressure-strain loops, can detect ventricular function impairment earlier than traditional echocardiography.</p><p><strong>Discussion: </strong>Echocardiography provides complementary diagnostic information for rheumatoid arthritis cardiac involvement through structural and functional assessment, yet limitations remain. Future work should establish multimodal ultrasound frameworks and develop AI-driven analytical platforms to enhance early detection and precision management.</p><p><strong>Conclusion: </strong>The continuous progress of ultrasound technology has significantly improved the accuracy of assessing cardiac damage in patients with rheumatoid arthritis, and it has become an essential examination method for screening heart diseases in such patients, providing strong support for early diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yukinori Okada, Norikazu Ohno, Yoshisuke Kitahara, Hirofumi Niioka, Koji Tanaka, Hiromitsu Ueda, Katsunori Tsujii, Masayuki Sato
{"title":"Voxel-Based Specific Regional Analysis System for Alzheimer's Disease and Arterial Spin Labeling in Brain Magnetic Resonance Imaging: A Comparative Study.","authors":"Yukinori Okada, Norikazu Ohno, Yoshisuke Kitahara, Hirofumi Niioka, Koji Tanaka, Hiromitsu Ueda, Katsunori Tsujii, Masayuki Sato","doi":"10.2174/0115734056337828250526070304","DOIUrl":"https://doi.org/10.2174/0115734056337828250526070304","url":null,"abstract":"<p><p><p> Introduction: Magnetic resonance imaging can differentiate Alzheimer-type dementia from dementia with Lewy bodies using voxel-based specific regional analysis systems for Alzheimer's disease and arterial spin labeling, which reveal reduced blood flow from the posterior cingulate gyrus to the precuneus in Alzheimer-type dementia. However, the relationship between voxel-based specific regional analysis system scores and arterial spin labeling remains unclear. To investigate the relationship between brain atrophy scores and arterial spin labeling values in the posterior cingulate precuneus. </p> <p> Methods: Participants with suspected dementia who underwent brain magnetic resonance imaging using a voxel-based regional analysis system were included. They were classified as follows: Group 1 (suspected Alzheimer-type dementia) had atrophy ≥2 in the volume of interest; Group 2 (suspected dementia with Lewy body) had atrophy <2 in the volume of interest and ≥0.2 in the gray and white matter of the dorsal brainstem; and Group 3 included those not meeting these criteria. Correlation values among atrophy within the volume of interest, percentage of atrophic areas, atrophy ratio, percentage of total brain atrophy, age, and maximum arterial spin labeling value at the posterior cingulate precuneus were evaluated. </p> <p> Results: Groups 1, 2, and 3 comprised 179, 143, and 197 patients, respectively. Arterial spin labeling values at the posterior cingulate precuneus were 77.0±24.4-77.3±25.2, 78.3±81.3-80.2±23.6, and 80.2±22.3-80.4±22.8 mL/min/100 g, respectively. Group 1 had a correlation coefficient between total brain atrophy and arterial spin labeling of -0.189 to-0.214 (P<0.01). Group 2 had a correlation coefficient between total brain atrophy and arterial spin labeling of -0.215 to -0.223 (P<0.01). Group 3 showed no significant correlations. No statistically significant difference was observed in ASL 1 and 2 values between the Alzheimer-type dementia and other groups (ASL 1: 74.5 mL/min/100 g vs. 78.8 mL/min/100 g, P=0.08; ASL 2: 74.8 mL/min/100 g vs. 79.2 mL/min/100 g, P=0.101). No statistically significant difference was observed in ASL 1 and 2 values between the Alzheimer-type dementia and DLB groups (ASL 1: 74.5 mL/min/100 g vs. 69.3. mL/min/100 g, P=0.093; ASL 2: 74.8 mL/min/100 g vs. 78.9 mL/min/100 g, P=0.258). </p> <p> Discussion: Reduced blood flow in the posterior cingulate gyrus and precuneus shows only a weak correlation with brain atrophy in both Alzheimer-type dementia and dementia with Lewy bodies. Therefore, it is not a reliable marker for differentiating Alzheimer-type dementia from dementia with Lewy bodies and other groups. </p> <p> Conclusion: It is necessary to avoid using cerebral blood flow assessment alone when diagnosing dementia. </p>.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gwanghyun Kim, Lyo Min Kwon, Young Soo Do, Kyung Sup Song, Wonju Hong
{"title":"Transcatheter Arterial Embolization of a Ruptured Bronchial Artery Aneurysm Presenting as Hematemesis: A Case Report.","authors":"Gwanghyun Kim, Lyo Min Kwon, Young Soo Do, Kyung Sup Song, Wonju Hong","doi":"10.2174/0115734056372341250628185446","DOIUrl":"https://doi.org/10.2174/0115734056372341250628185446","url":null,"abstract":"<p><strong>Background: </strong>Hematemesis is a rare manifestation of a bronchial artery aneurysm (BAA), as bleeding from a ruptured BAA typically occurs into the bronchial tree, leading to hemoptysis rather than gastrointestinal bleeding.</p><p><strong>Case presentations: </strong>A 71-year-old male presented to the emergency department with syncope and hematemesis. Computed tomography angiography (CTA) revealed a ruptured bronchial artery aneurysm in the posterior mediastinum, with contrast extravasation into the lower esophagus. The patient underwent transcatheter arterial embolization (TAE) using coils, an N-butyl cyanoacrylate and an ethiodized oil mixture. However, due to persistent bleeding signs and recanalization observed on follow-up CTA, a second TAE was performed the following day using the same technique. Hemostasis was achieved, and the patient recovered well, being discharged on the 16th day without complications.</p><p><strong>Conclusion: </strong>Ruptured BAA presenting as hematemesis is extremely rare, making it difficult to diagnose. Prompt diagnosis with CTA and timely intervention, such as TAE, can be important in achieving favorable outcomes and preventing life-threatening complications.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}