Yichuan Mao, Xiuzhen Yao, Gui Xu, Feng Yang, Xiangqun Zhou, Xiaoqin Wu, Weiqun Ao, Jun Lin
{"title":"Imaging Findings of Primary Squamous Cell Carcinoma of the Liver: Case Presentation and Literature Review.","authors":"Yichuan Mao, Xiuzhen Yao, Gui Xu, Feng Yang, Xiangqun Zhou, Xiaoqin Wu, Weiqun Ao, Jun Lin","doi":"10.2174/0115734056344249250108062855","DOIUrl":"https://doi.org/10.2174/0115734056344249250108062855","url":null,"abstract":"<p><strong>Introduction: </strong>Primary Squamous Cell Carcinoma of the Liver (PSCCL) is an exceptionally rare clinical entity characterized by diagnostic challenges, aggressive behavior, and poor prognosis. Globally, few studies have investigated PSCCL.</p><p><strong>Case presentation: </strong>We report the case of a 76-year-old male patient with PSCCL, detailing his clinical presentation and imaging findings, to offer insights into the preoperative diagnosis of this disease. The patient presented with upper abdominal pain that had lasted for over two weeks without any specific triggers. Laboratory tests revealed abnormal liver function. Ultrasound examination showed a large, solid, hypoechoic mass in the right anterior lobe of the liver with heterogeneous internal echoes. Color Doppler imaging detected limited blood flow signals. Contrast-enhanced Computed Tomography (CT) of the whole abdomen revealed a low-density mass with indistinct margins in the right lobe of the liver, showing uneven and progressive peripheral enhancement. Comprehensive whole-body CT, gastroscopy, and liver biopsy were performed, excluding metastatic disease in other organs. Based on the pathological findings from a percutaneous ultrasound-guided liver biopsy, the patient was diagnosed with PSCCL.</p><p><strong>Conclusion: </strong>PSCCL is a rare malignancy that presents significant diagnostic difficulties, often evading easy identification through clinical and imaging examinations. This case report aims to contribute to improving the preoperative diagnosis of PSCCL.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Background Parenchymal Enhancement in Breast MRI Correlates with Molecular Subtypes of Breast Cancer.","authors":"Hongyu Liu, Xinyue Chen, Yanna Wang, Xiaoping Yang, Yuxingzi Chen","doi":"10.2174/0115734056347327250117073638","DOIUrl":"https://doi.org/10.2174/0115734056347327250117073638","url":null,"abstract":"<p><strong>Purpose: </strong>MRI could be considered as a non-destructive disease diagnosis procedure, this procedure does not allow directly molecular types of cancer. Herein, we aimed to evaluate the correlation of breast MRI background parenchymal enhancement (BPE) and fibroglandular tissue (FGT) with the molecular subtypes and immunohistochemical markers of breast cancer.</p><p><strong>Methods: </strong>This was a single-cross-sectional retrospective study.Fifty-six patients diagnosed with unilateral breast cancer who underwent breast MRI scans before needle biopsy or surgery were selected. The relationship between qualitative and quantitative BPE/FGT ratios and the expression of breast cancer molecular subtypes and immunohistochemical markers were evaluated in patients with breast cancer.</p><p><strong>Results: </strong>Quantitative BPE (BPE%) of luminal A and luminal B was significantly lower than that of triple-negative breast cancer. There was no significant difference in the qualitative BPE/FGT between the different breast cancer subtypes. The quantitative BPE (BPE%) of estrogen receptor (ER)- negative tumors was higher than that of the ER-positive tumors, and the expression of FGT%, BPE%, and other immunohistochemical markers (human epidermal growth factor receptor-2(HER-2), progesterone receptor (PR), and Ki-67) were not significantly different. The proportion of high BPE distribution in HER-2 positive tumors was higher than that in the HER-2 negative group; however, there was no significant difference in the expression of qualitative BPE/FGT and other immunohistochemical markers (ER, PR, and Ki-67).</p><p><strong>Conclusion: </strong>There were significant differences in the levels of BPE among the different molecular subtypes. Therefore, BPE may be a potential imaging biomarker for the diagnosis of the molecular subtypes of breast cancer.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yawen Zhang, Leilei Zhou, Jun Yao, Hai Xu, Yu-Chen Chen, Xiaomin Yong
{"title":"Differentiation of Minute Pulmonary Meningothelial-Like Nodules and Adenocarcinoma In situ with CT Radiomics.","authors":"Yawen Zhang, Leilei Zhou, Jun Yao, Hai Xu, Yu-Chen Chen, Xiaomin Yong","doi":"10.2174/0115734056354822250217045544","DOIUrl":"https://doi.org/10.2174/0115734056354822250217045544","url":null,"abstract":"<p><strong>Background: </strong>An effective preoperative diagnosis between minute pulmonary meningothelial-like nodules (MPMNs) and adenocarcinoma in situ (AIS) can provide clinicians with appropriate treatment strategies.</p><p><strong>Objective: </strong>This study aimed to differentiate MPMNs from AIS via computed tomography (CT) radiomics approaches.</p><p><strong>Methods: </strong>Clinical and imaging data from fifty-one patients diagnosed with MPMNs and 55 patients diagnosed with AIS were collected from Jiangsu Province Hospital and Nanjing First Hospital from January 2016 to December 2022. All patients underwent chest CT scans before surgery. All CT images were segmented with ITK-SNAP software, and the radiomics features were further extracted with the Python PyRadiomics package. Least absolute shrinkage and selection operator (LASSO) regression analysis was used to select the optimal radiomics features for the construction of the model. The ROC curve was used to evaluate the diagnostic efficacy of the model.</p><p><strong>Results: </strong>After feature reduction and selection, 16 radiomics features were selected to construct the radiomics model. In the test set, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the k-nearest neighbor model were 87.5%, 88.9%, 96.9%, 77.8%, and 88.5%, respectively, and the AUC of the ROC curve was 0.969 (95% CI: 0.72-1.00).</p><p><strong>Conclusion: </strong>The CT radiomics model has exhibited high diagnostic value in the differential diagnosis between MPMNs and AIS.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Bronchogenic Cyst Detected by Ultrasound.","authors":"Lei Zhang, Dong-Hui Ji, Kuo-Peng Liang","doi":"10.2174/0115734056347512250219063009","DOIUrl":"https://doi.org/10.2174/0115734056347512250219063009","url":null,"abstract":"<p><strong>Background: </strong>Bronchogenic cysts are congenital cystic anomalies of the bronchus that originate from abnormal development of the bronchial tree during the embryonic period. Their common manifestation is a space-occupying lesion in the lungs or mediastinum. Common imaging modalities for detecting bronchogenic cysts include chest X-ray and chest computed tomography (CT) scans.</p><p><strong>Case presentation: </strong>A 24-year-old female presented with an abnormal space-occupying lesion in the mediastinum detected through imaging examinations. Echocardiography revealed a cystic mass located between the descending aorta and the right pulmonary artery. A CT scan identified a low-density mass with a distinct density relative to adjacent tissues, situated near the left main bronchus. The final diagnosis of a bronchogenic cyst was established following surgical intervention and pathological examination.</p><p><strong>Conclusion: </strong>Bronchogenic cysts are rare congenital anomalies. Common clinical symptoms include chest pain, cough, and dyspnea. On standard chest radiographs and CT scans, most cysts present as homogenous water-density shadows, with the mediastinum being the most frequently affected location. The diagnosis is confirmed through pathological examination. Surgical intervention remains the most effective treatment method, typically resulting in a favorable prognosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Significance and Predictive Value of Delphian Lymph Node in Papillary Thyroid Carcinoma.","authors":"Yaqi Cui, Yimeng Li, Xinlu Yin, Jiadong Wang","doi":"10.2174/0115734056360214250215155608","DOIUrl":"https://doi.org/10.2174/0115734056360214250215155608","url":null,"abstract":"<p><strong>Background: </strong>Delphian lymph node (DLN) metastasis is common in papillary thyroid cancer (PTC). However, few studies have specifically investigated the clinicopathologic characteristics of DLN metastasis in PTC. This study aimed to examine the incidence, risk factors, and predictive value of DLN in papillary thyroid carcinoma.</p><p><strong>Methods: </strong>In the present study, the clinicopathologic features and metastatic risks were statistically analyzed by reviewing 1837 patients with papillary thyroid carcinoma who underwent initial surgery in our department between January, 2022 and July, 2024.</p><p><strong>Results: </strong>Among the 1837 patients included in the study, DLN was detected in 925 patients (50.3%), of which 409 patients (22.3%) had confirmed DLN metastasis. In univariate analysis, DLN metastasis was correlated with age (≥55 years), bilateral cancer, multifocality, tumor location (isthmus cancer), central lymph node metastasis (CLNM), and lateral lymph node metastasis (LLNM). However, it was not correlated with gender distribution, tumor size, thyroiditis, thyroid-stimulating hormone (TSH) level, and BRAF mutation. Multivariate analysis showed that CLNM (p=0.03), LLNM (p=0.025), bilateral cancer, and tumor location (p=0.012) were independent risk factors for DLN metastasis. DLN involvement was mildly predictive of CLNM (sensitivity=29.76%, specificity=87.06%, positive predictive values=74.08%, negative predictive values=49. 93%, positive likelihood ratio=2.30, negative likelihood ratio=0.81) and moderately predictive of LLNM (sensitivity=49.36%, specificity=85.01%, positive predictive values=46.94%, negative predictive values=86.20%, positive likelihood ratio=3.29, negative likelihood ratio=0.60).</p><p><strong>Conclusion: </strong>Bilateral cancer, CLNM, LLNM, and isthmus cancer were independent risk factors for DLN metastasis. DLN metastasis could be used as a predictor for central and lateral lymph node metastasis. Positive DLN should be a warning signal to carefully evaluate central and lateral lymph nodes during thyroidectomy.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuanli Zhang, Hong Huang, Chongzhi Yin, Guizhi Zhang, Yang Wang, Rui Gao, Jinlin Song
{"title":"Clinical Evaluation of ODIS-1 Orthodontic Operation and Image Quality of Digital Imaging System.","authors":"Yuanli Zhang, Hong Huang, Chongzhi Yin, Guizhi Zhang, Yang Wang, Rui Gao, Jinlin Song","doi":"10.2174/0115734056345020250223150845","DOIUrl":"https://doi.org/10.2174/0115734056345020250223150845","url":null,"abstract":"<p><strong>Background: </strong>With the rapid development of computer technology, the application of digital technology to the display and processing of medical images has become a common concern. In recent years, oral digital imaging technology has received more and more attention.</p><p><strong>Objective: </strong>This paper mainly aims at the ODIS-1 oral digital imaging system to analyze and study the image quality and image aims at the ODIS-1 oral digital imaging system to analyze and study the image quality and processing technology, of which X-ray imaging is indispensable.</p><p><strong>Methods: </strong>In this paper, the ODIS-1 digital scanning technology is used to detect different types of dental tissues, and its application in diagnosing oral diseases is evaluated. This paper takes 320 inpatients as the research object and uses Kodak dental film to compare the image quality of different positions.</p><p><strong>Results: </strong>It is found that there is no significant difference in image quality between the maxillary anterior teeth and mandibular anterior teeth and the maxillary posterior teeth and mandibular posterior teeth (P>0.05); the image quality of maxillary anterior teeth, mandibular anterior teeth, and maxillary posterior teeth and mandibular teeth are significantly different (P<0.05); among the various positions of the ODIS-1 oral digital imaging system, the image quality of the anterior teeth area is the best, while the image quality of the maxillary posterior teeth area is the worst.</p><p><strong>Conclusion: </strong>However, the system has a variety of image post-processing functions, which can adjust the brightness and contrast of the image arbitrarily, select the area of interest in the image according to the detection requirements, and perform local amplification, edge enhancement, and other technologies to make the image achieve the best effect. In the case of poor image quality, the clarity of the image can be further improved through image post-processing and analysis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integration of Three-dimensional Visualization Reconstruction Technology with Problem-Based Learning in the Clinical Training of Resident Physicians Specialized in Pheochromocytoma.","authors":"Dong Wang","doi":"10.2174/0115734056327236250101052226","DOIUrl":"https://doi.org/10.2174/0115734056327236250101052226","url":null,"abstract":"<p><strong>Objective: </strong>We examined the effectiveness of integrating three-dimensional (3D) visualization reconstruction technology with Problem-Based Learning (PBL) in the clinical teaching of resident physicians focusing on pheochromocytoma.</p><p><strong>Methods: </strong>Fifty resident physicians specializing in urology at Peking Union Medical College Hospital were randomly divided into two groups over the period spanning January 2022 to January 2024: an experimental group and a control group. The experimental group underwent instruction utilizing a pedagogical approach that integrated 3D visualization reconstruction technology with PBL, while the control group used a traditional teaching model. A comparative analysis of examination performance and teaching satisfaction between both groups of resident physicians was conducted to assess the efficacy of the integrated 3D visualization and PBL teaching methods in clinical instruction.</p><p><strong>Results: </strong>The experimental group demonstrated superior performance in both theoretical assessment and clinical skills evaluation, along with heightened levels of teaching satisfaction compared to the control group, with statistically significant differences (p < 0.05). Additionally, the experimental group exhibited markedly higher scores in both theoretical examinations and practical assessments compared to their counterparts in the control group (p < 0.05). The results of theoretical examinations for the experimental group and the control group were 92.15±3.22 and 81.09±4.46, respectively (< 0.0001). The results of practical examinations for the experimental group and the control group were 90.17±3.48 and 70.75±5.11, respectively (< 0.0001).</p><p><strong>Conclusion: </strong>In the clinical teaching of training resident physicians specializing in urology for the management of pheochromocytoma, the integration of 3D visualization reconstruction technology with the PBL method significantly enhanced the teaching efficacy, improving both the quality of instruction and the level of satisfaction among participants.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qianqian Mao, Heng Wang, Jun Yao, Huiyou Chen, Yu-Chen Chen, Xindao Yin, Zhengqian Wang
{"title":"Left Basal Ganglia Stroke-induced more Alterations of Functional Connectivity: Evidence from an fMRI Study.","authors":"Qianqian Mao, Heng Wang, Jun Yao, Huiyou Chen, Yu-Chen Chen, Xindao Yin, Zhengqian Wang","doi":"10.2174/0115734056344477250222060225","DOIUrl":"https://doi.org/10.2174/0115734056344477250222060225","url":null,"abstract":"<p><strong>Background: </strong>The basal ganglia area is a frequent site of stroke, which commonly causes intricate functional impairments. This study aims to uncover disparities in static and dynamic functional connectivity (FC) of the brain in patients afflicted with left-sided basal ganglia stroke (L-BGS) and right-sided basal ganglia region stroke (R-BGS), furthermore scrutinising the mechanism behind the lateralisation of the stroke.</p><p><strong>Methods: </strong>A total of 23 patients with L-BGS and 20 patients with R-BGS were recruited, alongside 20 healthy control subjects. Resting-state functional magnetic resonance imaging and sliding window techniques were employed to conduct static and dynamic FC analyses on both patient groups and controls, which can enable a more refined evaluation of the variations in neural signals.</p><p><strong>Results: </strong>The inter-network connectivity analysis showed significant changes only in the L-BGS patient group (p < 0.05). The R-BGS group showed increased connectivity in the auditory and posterior visual networks, while the L-BGS group showed reduced connectivity. In dynamic connectivity analyses, the L-BGS group exhibited greater positive network connectivity reorganization.</p><p><strong>Conclusion: </strong>Within one month of stroke onset, the L-BGS group showed a more pronounced impairment of inter-network connectivity, alongside enhanced FC compensatory changes of a positive nature. Differential changes in the two patient groups may provide useful information for individualized rehabilitation strategies.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd Anjum, Sana Shahab, Shabir Ahmad, Taegkeun Whangbo
{"title":"A Novel Fragmentation-based Approach for Accurate Segmentation of Small-Sized Brain Tumors in MRI Images.","authors":"Mohd Anjum, Sana Shahab, Shabir Ahmad, Taegkeun Whangbo","doi":"10.2174/0115734056305784240821045425","DOIUrl":"https://doi.org/10.2174/0115734056305784240821045425","url":null,"abstract":"<p><strong>Aims: </strong>In the dynamic landscape of healthcare, integrating Artificial Intelligence paradigms has become essential for sophisticated brain image analysis, especially in tumor detection. This research addresses the need for heightened learning precision in handling sensitive medical images by introducing the Fragmented Segment Detection Technique.</p><p><strong>Background: </strong>The ever-evolving healthcare landscape demands advanced methods for brain image analysis, particularly in detecting tumors. This study responds to this need by introducing the Feature Segmentation and Detection Technique (FSDT), a novel approach designed to identify brain tumors precisely using MRI images. The focus is on enhancing detection accuracy, even for diminutive tumors. The primary objective of this study is to introduce and evaluate the efficacy of FSDT in identifying and sizing brain tumors through advanced medical image analysis. The proposed technique utilizes cross-section segmentation and pixel distribution analysis to improve detection accuracy, particularly in size-based tumor detection scenarios.</p><p><strong>Methods: </strong>The proposed technique commences by fragmenting the input through cross-section segmentation, enabling meticulous separation of pixel distribution in various sections. A Convolutional Neural Network then independently operates sequentially on the minimum and maximum representations. The segmented cross-section feature, exhibiting maximum accuracy, is employed in the neural network training process. Finetuning of the neural network optimizes feature distribution and pixel arrangements, specifically in consecutive size-based tumor detection scenarios.</p><p><strong>Results: </strong>The FSDT employs cross-sectional segmentation and pixel distribution analysis to enhance detection accuracy by leveraging a diverse dataset encompassing central nervous system CNS tumors. Comparative evaluations against existing methods, including ERV-Net, MRCNN, and ENet- B0, reveal FSDT's superiority in accuracy, training rate, analysis ratio, precision, recall, F1-score, and computational efficiency. The proposed technique demonstrates a remarkable 10.45% increase in accuracy, 14.12% in training rate, and a 10.78% reduction in analysis time.</p><p><strong>Conclusion: </strong>The proposed FSDT emerges as a promising solution for advancing the accurate identification and sizing of brain tumors through cutting-edge medical image analysis. The demonstrated improvements in accuracy, training rate, and analysis time showcase its potential for effective realworld healthcare applications.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Demographic Characteristics of Pneumoconiosis Cases: A Single Centre Experience.","authors":"Bilge Akgündüz, Sermin Tok","doi":"10.2174/0115734056375744250225063355","DOIUrl":"https://doi.org/10.2174/0115734056375744250225063355","url":null,"abstract":"<p><strong>Background: </strong>Pneumoconiosis is a preventable occupational lung disease that is caused by the inhalation of inorganic occupational dust. The disease can progress and result in functional impairment. Profusion scores are crucial for the assessment of disease severity.</p><p><strong>Objective: </strong>This study aimed to determine the prevalence of pneumoconiosis cases with a profusion score of 0/1 and explore the correlation between pneumoconiosis and smoking behavior in the industrial sector.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was carried out in this work. Pneumoconiosis was diagnosed with occupational exposure histories and thoracic computed tomography (CT) findings. The study included patients admitted to the occupational diseases outpatient clinic at Eskişehir City Hospital for occupational or pulmonary conditions from January 2021 to July 2023. The collected data included age, sex, smoking status, packyears, industry of employment, specific departments, occupations, exposure to occupational and non-occupational environmental factors, duration of exposure, laboratory results, pulmonary function test outcomes, thoracic CT findings, and International Classification of Radiographs of Pneumoconiosis score.</p><p><strong>Results: </strong>Among the 361 patients, 99.4% were male and 62.3% were current smokers. We observed a profusion score of 0/1 in 15% (n = 54) of the cases. Patients with a 0/1 profusion score had better lung function than those with higher scores, with the FEV1/FVC ratio declining as the profusion score increased. Non-smokers with progressive massive fibrosis had significantly lower FEV1/FVC ratios compared to other non-smokers.</p><p><strong>Conclusion: </strong>In order to avert the progression of early-stage cases, it is significant that we reevaluate occupational health policies and measures, regardless of compensation.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}