Current Medical Imaging Reviews最新文献

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Prediction of Cardiac Remodeling and/or Myocardial Fibrosis Based on Hemodynamic Parameters of Vena Cava in Athletes. 基于运动员腔静脉血流动力学参数预测心脏重构和/或心肌纤维化。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056316396241227064057
Bin-Yao Liu, Fan Zhang, Min-Song Tang, Xing-Yuan Kou, Qian Liu, Xin-Rong Fan, Rui Li, Jing Chen
{"title":"Prediction of Cardiac Remodeling and/or Myocardial Fibrosis Based on Hemodynamic Parameters of Vena Cava in Athletes.","authors":"Bin-Yao Liu, Fan Zhang, Min-Song Tang, Xing-Yuan Kou, Qian Liu, Xin-Rong Fan, Rui Li, Jing Chen","doi":"10.2174/0115734056316396241227064057","DOIUrl":"10.2174/0115734056316396241227064057","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the hemodynamic changes in the vena cava and predict the likelihood of Cardiac Remodeling (CR) and Myocardial Fibrosis (MF) in athletes utilizing four-dimensional (4D) parameters.</p><p><strong>Materials and methods: </strong>A total of 108 athletes and 29 healthy sedentary controls were prospectively recruited and underwent Cardiac Magnetic Resonance (CMR) scanning. The 4D flow parameters, including both general and advanced parameters of four planes for the Superior Vena Cava (SVC) and Inferior Vena Cava (IVC) (sheets 1-4), were measured and compared between the different groups. Four machine learning models were employed to predict the occurrence of CR and/or MF.</p><p><strong>Results: </strong>Most general 4D flow parameters related to VC were increased in athletes and positive athletes compared to controls (p < 0.05). Gradient Boosting Machine (GBM) was the most effective model in sheet 2 of SVC, with the area under the curve values of 0.891, accuracy of 85.2%, sensitivity of 84.6%, and specificity of 85.4%. The top five predictors in descending order were as follows: net positive volume, forward volume, waist circumference, body weight, and body surface area.</p><p><strong>Conclusion: </strong>Physical activity can induce a high flow state in the vena cava. CR and/or MF may elevate the peak velocity and maximum pressure gradient of the IVC. This study successfully constructed a GBM model with high efficacy for predicting CR and/or MF. This model may provide guidance on the frequency of follow-up and the development of appropriate exercise plans for athletes.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056316396"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV Infection Complicated with Cytomegalovirus Colitis: A Case Report of 18FFDG PET/CT Imaging. HIV感染合并巨细胞病毒性结肠炎1例:18FFDG PET/CT显像
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056361753241226065721
Shengwei Fang, Peipei Zhang
{"title":"HIV Infection Complicated with Cytomegalovirus Colitis: A Case Report of 18FFDG PET/CT Imaging.","authors":"Shengwei Fang, Peipei Zhang","doi":"10.2174/0115734056361753241226065721","DOIUrl":"10.2174/0115734056361753241226065721","url":null,"abstract":"<p><strong>Background: </strong>Cytomegalovirus (CMV) infection is common in the digestive and central nervous systems and can infect the entire digestive tract from the mouth to the rectum. In immunocompromised patients, CMV infection is prone to develop into CMV disease, especially in Acquired Immune Deficiency Syndrome (AIDS) patients. Severe cases may accelerate the progression of AIDS patients and form systemic CMV infection. Timely diagnosis and treatment are very important for the prognosis of patients.</p><p><strong>Case presentation: </strong>In this paper, we report a 36-year-old man with a Human Immunodeficiency Virus (HIV) infection complicated with CMV colitis. Three weeks ago, he developed abdominal pain with fresh blood in the stool, accompanied by anal pain. He was found to be HIV positive 8 years ago. An enhanced CT scan showed edema and irregular thickening of the rectal wall, obvious enhancement of the mucosa, and multiple enlarged lymph nodes around. 18F-FDG PET/CT imaging displayed diffuse rectum wall thickening and increased glucose metabolism, and the SUV max was 12.7. There were multiple enlarged lymph nodes around the rectum, glucose metabolism was increased, and the SUVmax was 4.6.</p><p><strong>Conclusion: </strong>18F-FDG-PET imaging technology has potential value in the diagnosis of CMV colitis, especially in immunocompromised patients. Detection of FDG concentrations in the colon wall can help diagnose CMV infection and understand the extent of the lesion, which is essential for the timely initiation of antiviral therapy.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056361753"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal Cord Image Denoising Using Dncnn Algorithm. 基于Dncnn算法的脊髓图像去噪。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056337613241209072322
R Jerlin, Priya Murugasen, N R Shanker
{"title":"Spinal Cord Image Denoising Using Dncnn Algorithm.","authors":"R Jerlin, Priya Murugasen, N R Shanker","doi":"10.2174/0115734056337613241209072322","DOIUrl":"10.2174/0115734056337613241209072322","url":null,"abstract":"<p><strong>Background: </strong>Spinal image denoising plays a vital role in the accurate diagnosis of disc herniation (DH).</p><p><strong>Objective: </strong>Traditional denoising algorithms perform less due Limited Directional Selectivity problem and do not adequately capture directional information in pixels. Traditional algorithms' edge representation and texture details are insufficient for the earlier detection of DH. Limited Directional Selectivity leads to inaccurate diagnosis and classification of Disc Herniation (DH) stages. The DH stages are (i) Degeneration (ii) Prolapse (iii) Extrusion and (iv) Sequestration. Moreover, detection of DH size below 2mm using MR image is the major problem.</p><p><strong>Methods: </strong>To solve the above problem, spinal cord MR images fed to the proposed Parrot optimization tuned Denoising Convolutional Neural Network (Po- DnCNN) algorithm for perspective enhancement of nucleus pulposus region in the spinal cord, vertebrae. The perspective enhancement of Spinal cord image led to the accurate classification of stages and earlier detection of DH by using the proposed Hippopotamus optimization- Fast Hybrid Vision Transformer (Ho-FastViT) algorithm. For this study, spinal cord MR images are obtained from the Grand Challenge website - SPIDER dataset.</p><p><strong>Results: </strong>The proposed Po-DnCNN method and Ho-FastViT results are analysed quantitatively and qualitatively based on the edge, contrast, classification of the stage, and enhancement of the projected nucleus pulposus region in the spinal cord and vertebrae. The predicted DH results using the proposed method are compared with the manual Pfirrman Grade value of the spinal card method.</p><p><strong>Conclusion: </strong>Proposed method is better than traditional methods for earlier detection of DH. Po-DnCNN and Ho-FastViat methods give high accuracy of about 98% and 97% compared to traditional methods.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":"21 1","pages":"e15734056337613"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Typical Computed Tomography Findings of Primary Fallopian Tube Carcinoma. 原发性输卵管癌的典型ct表现。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056274106240119052437
Tongtong Tian, Rongrong Ding, Tongmin Xue, Jun Sun, Jun Ling
{"title":"The Typical Computed Tomography Findings of Primary Fallopian Tube Carcinoma.","authors":"Tongtong Tian, Rongrong Ding, Tongmin Xue, Jun Sun, Jun Ling","doi":"10.2174/0115734056274106240119052437","DOIUrl":"https://doi.org/10.2174/0115734056274106240119052437","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to investigate the imaging features of primary fallopian tube carcinoma (PFTC).</p><p><strong>Methods: </strong>Imaging findings of 12 PFTC patients were retrospectively studied. Multi-slice computed tomography (CT, MSCT) was performed to investigate tumor location, size, density, appearance (cystic/solid), enhancement pattern, and metastasis.</p><p><strong>Results: </strong>Twelve women aged 34-67 (mean=54.3) years were presented with pelvic pain (n=6), vaginal discharge (n=5), and incidental pelvic masses (n=3). The tumor diameters of PFTC varied from 3.3 to 6.8 cm (mean=4.7 cm). Ten cases were unilateral, and two were bilateral. The lesions were adnexal tubular-shaped cystic masses with mucosal papillary nodes in six cases, irregular cystic and solid masses in four cases, and sausage-shaped solid masses in two cases. The plain CT values ranged from 15 to 35 HU (mean, 28 HU). On enhanced CT, the enhancement of the solid composition was lower than that of the myometrium in all phases. CT values in arterial and venous phases were 55-62 and 60-63 HU, respectively, with average values of 58.6 and 61 HU. The metastasis sites included the ovary (n=2), omentum (n=3), retroperitoneal lymph nodes (n=5), pelvic lymph nodes (n=5), and inguinal lymph nodes (n=2). Seven cases exhibited pelvic fluid, and seven exhibited round ligament thickening on the lesioned side.</p><p><strong>Conclusion: </strong>In patients presenting with vaginal discharge or genital bleeding and sausage-shaped or tubal-shaped cystic, solid, or solid-cystic complexes in the adnexal portion associated with hydrosalpinx and peritumoral ascites, PFTC should be considered in the diagnosis, especially in tumors associated with round ligament thickening.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":"21 ","pages":"e15734056274106"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploration of Cervical Cancer Image Processing and Detection Based on URCNNs. 基于urcnn的宫颈癌图像处理与检测探索。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056333197241211162651
Cheng Cheng, Yi Yang, Youshan Qu
{"title":"Exploration of Cervical Cancer Image Processing and Detection Based on URCNNs.","authors":"Cheng Cheng, Yi Yang, Youshan Qu","doi":"10.2174/0115734056333197241211162651","DOIUrl":"10.2174/0115734056333197241211162651","url":null,"abstract":"<p><strong>Background: </strong>Cervical cancer is a prevalent malignancy among women, often asymptomatic in early stages, complicating detection.</p><p><strong>Objective: </strong>This study aims to investigate innovative techniques for early cervical cancer detection using a novel U-RCNNS model.</p><p><strong>Methods: </strong>Cervical epithelial cell images stained with hematoxylin and eosin (HE) were analyzed using the U-RCNNS model, which integrates U-Net for segmentation and R-CNN for object detection, incorporating dilated convolution techniques.</p><p><strong>Results: </strong>The U-RCNNS model significantly improved the accuracy of detecting and segmenting cervical cancer cells, with the enhanced Mask R-CNN showing notable advancements over the baseline model.</p><p><strong>Conclusion: </strong>The U-RCNNS model presents a promising solution for early cervical cancer detection, offering improved accuracy compared to traditional methods and highlighting its potential for clinical application in early diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056333197"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Features and Ultrasonographic Manifestations of Retroperitoneal Nerve Sheath Tumors. 腹膜后神经鞘瘤的临床特征和超声表现
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056348636241213120140
Xiaoqing Wang, Xiaoying Zhang, Rui Zhao, Yan Liu, Chaoyang Wen, Haining Zheng
{"title":"Clinical Features and Ultrasonographic Manifestations of Retroperitoneal Nerve Sheath Tumors.","authors":"Xiaoqing Wang, Xiaoying Zhang, Rui Zhao, Yan Liu, Chaoyang Wen, Haining Zheng","doi":"10.2174/0115734056348636241213120140","DOIUrl":"10.2174/0115734056348636241213120140","url":null,"abstract":"<p><strong>Objectives: </strong>Retroperitoneal nerve sheath tumors are uncommon, representing a small fraction of all primary retroperitoneal neoplasms. Accurate differentiation between benign and malignant forms is essential for optimal clinical management. This study assessed the clinical profiles and sonographic traits of retroperitoneal nerve sheath tumors with the goal of enhancing diagnostic precision and developing therapeutic strategies.</p><p><strong>Methods: </strong>A retrospective analysis of patients diagnosed with benign retroperitoneal nerve sheath tumors who completed surgical treatment and underwent ultrasound imaging was carried out. Tumors were classified based on sonographic features and blood flow characteristics as per Adler's grading system. Statistical analysis was performed using SPSS 25.0. ROC curve analysis was carried out to determine the optimal diagnostic cutoff values.</p><p><strong>Results: </strong>A total of 49 patients were included in the study. There were no significant variances in age, gender, or tumor localization among the groups. However, pronounced disparities were observed in tumor number, size, shape, definition of borders, internal echo pattern, structural composition, presence of calcification, and blood flow signals between the classic and malignant groups. Notably, malignant tumors tended to manifest as larger masses with indistinct margins and irregular shapes. The maximum tumor diameter emerged as a discriminating factor for malignancy, with a diagnostic cutoff of 9.9 cm, yielding an AUC of 0.754 from the ROC curve analysis.</p><p><strong>Conclusion: </strong>This study outlines the distinctive clinical and sonographic features of retroperitoneal nerve sheath tumors, with a particular focus on malignant subtypes. Ultrasonography emerges as a valuable diagnostic tool, contributing to the differentiation of tumor categories and potentially to the development of targeted treatment strategies. The identification of specific sonographic markers may facilitate the early detection and detailed characterization of these tumors, which could contribute to improved patient outcomes.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056348636"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging and Clinical Features of Primary Thoracic Lymphangioma 原发性胸段淋巴管瘤的影像学与临床特征。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056346925241226125948
Mingxia Zhang, Ling Li, Meng Huo, Lei Sun, Chunyan Zhang, Ying Sun, Rengui Wang
{"title":"Imaging and Clinical Features of Primary Thoracic Lymphangioma","authors":"Mingxia Zhang, Ling Li, Meng Huo, Lei Sun, Chunyan Zhang, Ying Sun, Rengui Wang","doi":"10.2174/0115734056346925241226125948","DOIUrl":"10.2174/0115734056346925241226125948","url":null,"abstract":"<p><strong>Background: </strong>Primary thoracic lymphangioma is a rare disease. Most of the previous studies are comprised of individual case reports, with a very limited number of patients included.</p><p><strong>Objective: </strong>This study aims to investigate the chest computed tomography (CT) imaging features and clinical manifestations of thoracic lymphangioma, thereby enhancing our understanding of the condition.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 62 patients diagnosed with thoracic lymphangioma, comprising 32 males and 30 females. The study focused on analyzing the chest CT imaging features and the clinical manifestations observed in these patients.</p><p><strong>Results: </strong>The incidence rates of thoracic lymphangioma did not differ significantly between males and females; however, it was more frequently observed in children and adolescents. The most common clinical symptoms included cough, fever, chylothorax, chylous pericardium, and lymphedema. The mediastinum (82.3%) emerged as the most frequent location for thoracic lymphangioma, followed by the chest wall (62.9%), bone (40.3%), and pleura (32.3%). Pulmonary lymphangioma, the least prevalent subtype (19.4%), exhibited a propensity to induce respiratory symptoms, frequently manifesting as a generalized lymphatic anomaly (GLA). Furthermore, elevated levels of D-dimer were detected in 34 patients (54.8%) with thoracic lymphangioma.</p><p><strong>Conclusions: </strong>Imaging examinations play a crucial role in assisting clinicians in making more accurate early diagnoses of thoracic lymphangioma. They are also helpful for assessing the extent of systemic infiltration and enhancing diagnostic precision. With radiological assessment, clinicians could more readily select appropriate therapeutic treatments and monitor the progression of follow-up care.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056346925"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic Resonance Imaging Study on Older Patients with Cognitive Impairment and Depression. 老年认知功能障碍伴抑郁的磁共振成像研究。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056281104241220113235
Shuang Zhang, Yuping Qin, Meng Ding, Jining Yang, Tao Zhang
{"title":"Magnetic Resonance Imaging Study on Older Patients with Cognitive Impairment and Depression.","authors":"Shuang Zhang, Yuping Qin, Meng Ding, Jining Yang, Tao Zhang","doi":"10.2174/0115734056281104241220113235","DOIUrl":"10.2174/0115734056281104241220113235","url":null,"abstract":"<p><strong>Background: </strong>Understanding brain changes in older patients with depression and their relationship with cognitive abilities may aid in the diagnosis of depression in this population. This study aimed to explore the association between brain lesions and cognitive performance in older patients with depression.</p><p><strong>Methods: </strong>We utilized magnetic resonance imaging data from a previous study, which included older adults with and without depression. Smoothed Regional Homogeneity (ReHo) and local brain Amplitude of Low-frequency Fluctuation (ALFF) values were assessed to examine brain activity.</p><p><strong>Results: </strong>The analysis revealed decreased ReHo in the left middle temporal gyrus, left middle frontal gyrus, and left precuneus, as well as increased local ALFF in the right middle occipital gyrus, left postcentral gyrus, and right precentral gyrus in older patients with depression. These alterations may contribute to behavioral and cognitive changes. However, no significant relationship was found between ReHo values and Montreal Cognitive Assessment (MoCA) scores. In contrast, increased local ALFF in the left postcentral gyrus and right precentral gyrus was negatively correlated with MoCA scores.</p><p><strong>Conclusion: </strong>This study demonstrated a significant association between regional brain alterations in patients with depression and cognitive behavior. Thus, this work identified functional brain regions and cognitive performance in older adults with depression, highlighting specific brain regions that play a crucial role in cognitive abilities in this population.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056281104"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Robust Approach to Early Glaucoma Identification from Retinal Fundus Images using Dirichlet-based Weighted Average Ensemble and BayesianOptimization 利用基于 Dirichlet 的加权平均集合和贝叶斯优化从视网膜眼底图像识别早期青光眼的稳健方法。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056335762250128095107
Mohamed Mouhafid, Yatong Zhou, Chunyan Shan, Zhitao Xiao
{"title":"A Robust Approach to Early Glaucoma Identification from Retinal Fundus Images using Dirichlet-based Weighted Average Ensemble and Bayesian\u0000Optimization","authors":"Mohamed Mouhafid, Yatong Zhou, Chunyan Shan, Zhitao Xiao","doi":"10.2174/0115734056335762250128095107","DOIUrl":"10.2174/0115734056335762250128095107","url":null,"abstract":"<p><strong>Objective: </strong>Glaucoma is a leading cause of irreversible visual impairment and blindness worldwide, primarily linked to increased intraocular pressure (IOP). Early detection is essential to prevent further visual impairment, yet the manual diagnosis of retinal fundus images (RFIs) is both time-consuming and inefficient. Although automated methods for glaucoma detection (GD) exist, they often rely on individual models with manually optimized hyperparameters. This study aims to address these limitations by proposing an ensemble-based approach that integrates multiple deep learning (DL) models with automated hyperparameter optimization, with the goal of improving diagnostic accuracy and enhancing model generalization for practical clinical applications.</p><p><strong>Materials and methods: </strong>The RFIs used in this study were sourced from two publicly available datasets (ACRIMA and ORIGA), consisting of a total of 1,355 images for GD. Our method combines a custom Multi-branch convolutional neural network (CNN), pretrained MobileNet, and DenseNet201 to extract complementary features from RFIs. Moreover, to optimize model performance, we apply Bayesian Optimization (BO) for automated hyperparameter tuning, eliminating the need for manual adjustments. The predictions from these models are then combined using a Dirichlet-based Weighted Average Ensemble (Dirichlet-WAE), which adaptively adjusts the weight of each model based on its performance.</p><p><strong>Results: </strong>The proposed ensemble model demonstrated state-of-the-art performance, achieving an accuracy (ACC) of 95.09%, precision (PREC) of 95.51%, sensitivity (SEN) of 94.55%, an F1-score (F1) of 94.94%, and an area under the curve (AUC) of 0.9854. The innovative Dirichlet-based WAE substantially reduced the false positive rate, enhancing diagnostic reliability for GD. When compared to individual models, the ensemble method consistently outperformed across all evaluation metrics, underscoring its robustness and potential scalability for clinical applications.</p><p><strong>Conclusion: </strong>The integration of ensemble learning (EL) and advanced optimization techniques significantly improved the ACC of GD in RFIs. The enhanced WAE method proved to be a critical factor in achieving well-balanced and highly accurate diagnostic performance, underscoring the importance of EL in medical diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056335762"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Machine Learning Model Based on Multi-Phase Contrast-enhanced CT for the Preoperative Prediction of the Muscle-Invasive Status of Bladder Cancer. 基于多期增强CT的机器学习模型用于膀胱癌肌肉侵袭状态的术前预测。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056377754250304040058
Xucheng He, Yuqing Chen, Shanshan Zhou, Guisheng Wang, Rongrong Hua, Caihong Li, Yang Wang, Xiaoxia Chen, Ju Ye
{"title":"A Machine Learning Model Based on Multi-Phase Contrast-enhanced CT for the Preoperative Prediction of the Muscle-Invasive Status of Bladder Cancer.","authors":"Xucheng He, Yuqing Chen, Shanshan Zhou, Guisheng Wang, Rongrong Hua, Caihong Li, Yang Wang, Xiaoxia Chen, Ju Ye","doi":"10.2174/0115734056377754250304040058","DOIUrl":"10.2174/0115734056377754250304040058","url":null,"abstract":"<p><strong>Background: </strong>Muscle infiltration of bladder cancer has become the most important index to evaluate its prognosis. Machine learning is expected to accurately identify its muscle infiltration status on images.</p><p><strong>Objective: </strong>This study aimed to establish and validate a machine learning prediction model based on multi-phase contrast-enhanced CT (MCECT) for preoperatively evaluating the muscle-invasive status of bladder cancer.</p><p><strong>Methods: </strong>A retrospective study was conducted on bladder cancer patients who underwent surgical resection and pathological confirmation by MCECT scans. They were randomly divided into training and testing groups at a ratio of 8:2; we used an independent external testing set for verification. The radiomics features of lesions were extracted from MCECT images and radiomics signatures were established by dual sample T-test and least absolute shrinkage selection operator (LASSO) regression. Afterward, four machine learning classifier models were established. The receiver operating characteristic (ROC) curve, calibration, and decision curve analysis were employed to evaluate the efficiency of the model and analyze diagnostic performance using accuracy, precision, sensitivity, specificity, and F1-score.</p><p><strong>Results: </strong>The best predictive model was found to have logic regression as the classifier. The AUC value was 0.89 (5-fold cross-validation range 0.83-0.96) in the training group, 0.80 in the test group, and 0.87 in the external testing group. In the testing and external testing group, the diagnostic accuracy, precision, sensitivity, specificity, and F1-score were 0.759, 0.826, 0.863, 0.729, 0.785, and 0.794, 0.755, 0.953, 0.720, and 0.809, respectively.</p><p><strong>Conclusion: </strong>The machine learning model showed good accuracy in predicting the muscle infiltration status of bladder cancer before surgery.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056377754"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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