Current Medical Imaging Reviews最新文献

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Imaging and Clinical Features of Primary Thoracic Lymphangioma 原发性胸段淋巴管瘤的影像学与临床特征。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056346925241226125948
Mingxia Zhang, Ling Li, Meng Huo, Lei Sun, Chunyan Zhang, Ying Sun, Rengui Wang
{"title":"Imaging and Clinical Features of Primary Thoracic Lymphangioma","authors":"Mingxia Zhang, Ling Li, Meng Huo, Lei Sun, Chunyan Zhang, Ying Sun, Rengui Wang","doi":"10.2174/0115734056346925241226125948","DOIUrl":"10.2174/0115734056346925241226125948","url":null,"abstract":"<p><strong>Background: </strong>Primary thoracic lymphangioma is a rare disease. Most of the previous studies are comprised of individual case reports, with a very limited number of patients included.</p><p><strong>Objective: </strong>This study aims to investigate the chest computed tomography (CT) imaging features and clinical manifestations of thoracic lymphangioma, thereby enhancing our understanding of the condition.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 62 patients diagnosed with thoracic lymphangioma, comprising 32 males and 30 females. The study focused on analyzing the chest CT imaging features and the clinical manifestations observed in these patients.</p><p><strong>Results: </strong>The incidence rates of thoracic lymphangioma did not differ significantly between males and females; however, it was more frequently observed in children and adolescents. The most common clinical symptoms included cough, fever, chylothorax, chylous pericardium, and lymphedema. The mediastinum (82.3%) emerged as the most frequent location for thoracic lymphangioma, followed by the chest wall (62.9%), bone (40.3%), and pleura (32.3%). Pulmonary lymphangioma, the least prevalent subtype (19.4%), exhibited a propensity to induce respiratory symptoms, frequently manifesting as a generalized lymphatic anomaly (GLA). Furthermore, elevated levels of D-dimer were detected in 34 patients (54.8%) with thoracic lymphangioma.</p><p><strong>Conclusions: </strong>Imaging examinations play a crucial role in assisting clinicians in making more accurate early diagnoses of thoracic lymphangioma. They are also helpful for assessing the extent of systemic infiltration and enhancing diagnostic precision. With radiological assessment, clinicians could more readily select appropriate therapeutic treatments and monitor the progression of follow-up care.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056346925"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnetic Resonance Imaging Study on Older Patients with Cognitive Impairment and Depression. 老年认知功能障碍伴抑郁的磁共振成像研究。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056281104241220113235
Shuang Zhang, Yuping Qin, Meng Ding, Jining Yang, Tao Zhang
{"title":"Magnetic Resonance Imaging Study on Older Patients with Cognitive Impairment and Depression.","authors":"Shuang Zhang, Yuping Qin, Meng Ding, Jining Yang, Tao Zhang","doi":"10.2174/0115734056281104241220113235","DOIUrl":"10.2174/0115734056281104241220113235","url":null,"abstract":"<p><strong>Background: </strong>Understanding brain changes in older patients with depression and their relationship with cognitive abilities may aid in the diagnosis of depression in this population. This study aimed to explore the association between brain lesions and cognitive performance in older patients with depression.</p><p><strong>Methods: </strong>We utilized magnetic resonance imaging data from a previous study, which included older adults with and without depression. Smoothed Regional Homogeneity (ReHo) and local brain Amplitude of Low-frequency Fluctuation (ALFF) values were assessed to examine brain activity.</p><p><strong>Results: </strong>The analysis revealed decreased ReHo in the left middle temporal gyrus, left middle frontal gyrus, and left precuneus, as well as increased local ALFF in the right middle occipital gyrus, left postcentral gyrus, and right precentral gyrus in older patients with depression. These alterations may contribute to behavioral and cognitive changes. However, no significant relationship was found between ReHo values and Montreal Cognitive Assessment (MoCA) scores. In contrast, increased local ALFF in the left postcentral gyrus and right precentral gyrus was negatively correlated with MoCA scores.</p><p><strong>Conclusion: </strong>This study demonstrated a significant association between regional brain alterations in patients with depression and cognitive behavior. Thus, this work identified functional brain regions and cognitive performance in older adults with depression, highlighting specific brain regions that play a crucial role in cognitive abilities in this population.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056281104"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Robust Approach to Early Glaucoma Identification from Retinal Fundus Images using Dirichlet-based Weighted Average Ensemble and BayesianOptimization 利用基于 Dirichlet 的加权平均集合和贝叶斯优化从视网膜眼底图像识别早期青光眼的稳健方法。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056335762250128095107
Mohamed Mouhafid, Yatong Zhou, Chunyan Shan, Zhitao Xiao
{"title":"A Robust Approach to Early Glaucoma Identification from Retinal Fundus Images using Dirichlet-based Weighted Average Ensemble and Bayesian\u0000Optimization","authors":"Mohamed Mouhafid, Yatong Zhou, Chunyan Shan, Zhitao Xiao","doi":"10.2174/0115734056335762250128095107","DOIUrl":"10.2174/0115734056335762250128095107","url":null,"abstract":"<p><strong>Objective: </strong>Glaucoma is a leading cause of irreversible visual impairment and blindness worldwide, primarily linked to increased intraocular pressure (IOP). Early detection is essential to prevent further visual impairment, yet the manual diagnosis of retinal fundus images (RFIs) is both time-consuming and inefficient. Although automated methods for glaucoma detection (GD) exist, they often rely on individual models with manually optimized hyperparameters. This study aims to address these limitations by proposing an ensemble-based approach that integrates multiple deep learning (DL) models with automated hyperparameter optimization, with the goal of improving diagnostic accuracy and enhancing model generalization for practical clinical applications.</p><p><strong>Materials and methods: </strong>The RFIs used in this study were sourced from two publicly available datasets (ACRIMA and ORIGA), consisting of a total of 1,355 images for GD. Our method combines a custom Multi-branch convolutional neural network (CNN), pretrained MobileNet, and DenseNet201 to extract complementary features from RFIs. Moreover, to optimize model performance, we apply Bayesian Optimization (BO) for automated hyperparameter tuning, eliminating the need for manual adjustments. The predictions from these models are then combined using a Dirichlet-based Weighted Average Ensemble (Dirichlet-WAE), which adaptively adjusts the weight of each model based on its performance.</p><p><strong>Results: </strong>The proposed ensemble model demonstrated state-of-the-art performance, achieving an accuracy (ACC) of 95.09%, precision (PREC) of 95.51%, sensitivity (SEN) of 94.55%, an F1-score (F1) of 94.94%, and an area under the curve (AUC) of 0.9854. The innovative Dirichlet-based WAE substantially reduced the false positive rate, enhancing diagnostic reliability for GD. When compared to individual models, the ensemble method consistently outperformed across all evaluation metrics, underscoring its robustness and potential scalability for clinical applications.</p><p><strong>Conclusion: </strong>The integration of ensemble learning (EL) and advanced optimization techniques significantly improved the ACC of GD in RFIs. The enhanced WAE method proved to be a critical factor in achieving well-balanced and highly accurate diagnostic performance, underscoring the importance of EL in medical diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056335762"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Machine Learning Model Based on Multi-Phase Contrast-enhanced CT for the Preoperative Prediction of the Muscle-Invasive Status of Bladder Cancer. 基于多期增强CT的机器学习模型用于膀胱癌肌肉侵袭状态的术前预测。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056377754250304040058
Xucheng He, Yuqing Chen, Shanshan Zhou, Guisheng Wang, Rongrong Hua, Caihong Li, Yang Wang, Xiaoxia Chen, Ju Ye
{"title":"A Machine Learning Model Based on Multi-Phase Contrast-enhanced CT for the Preoperative Prediction of the Muscle-Invasive Status of Bladder Cancer.","authors":"Xucheng He, Yuqing Chen, Shanshan Zhou, Guisheng Wang, Rongrong Hua, Caihong Li, Yang Wang, Xiaoxia Chen, Ju Ye","doi":"10.2174/0115734056377754250304040058","DOIUrl":"10.2174/0115734056377754250304040058","url":null,"abstract":"<p><strong>Background: </strong>Muscle infiltration of bladder cancer has become the most important index to evaluate its prognosis. Machine learning is expected to accurately identify its muscle infiltration status on images.</p><p><strong>Objective: </strong>This study aimed to establish and validate a machine learning prediction model based on multi-phase contrast-enhanced CT (MCECT) for preoperatively evaluating the muscle-invasive status of bladder cancer.</p><p><strong>Methods: </strong>A retrospective study was conducted on bladder cancer patients who underwent surgical resection and pathological confirmation by MCECT scans. They were randomly divided into training and testing groups at a ratio of 8:2; we used an independent external testing set for verification. The radiomics features of lesions were extracted from MCECT images and radiomics signatures were established by dual sample T-test and least absolute shrinkage selection operator (LASSO) regression. Afterward, four machine learning classifier models were established. The receiver operating characteristic (ROC) curve, calibration, and decision curve analysis were employed to evaluate the efficiency of the model and analyze diagnostic performance using accuracy, precision, sensitivity, specificity, and F1-score.</p><p><strong>Results: </strong>The best predictive model was found to have logic regression as the classifier. The AUC value was 0.89 (5-fold cross-validation range 0.83-0.96) in the training group, 0.80 in the test group, and 0.87 in the external testing group. In the testing and external testing group, the diagnostic accuracy, precision, sensitivity, specificity, and F1-score were 0.759, 0.826, 0.863, 0.729, 0.785, and 0.794, 0.755, 0.953, 0.720, and 0.809, respectively.</p><p><strong>Conclusion: </strong>The machine learning model showed good accuracy in predicting the muscle infiltration status of bladder cancer before surgery.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056377754"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphology and Distribution of Fat Globules in Osteomyelitis on Magnetic Resonance Imaging. 骨髓炎脂肪球的磁共振成像形态和分布。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056331041250116092101
Li-Yuan Xie, Lei Cao, Wen-Juan Wu, Ji-Cun Liu, Na Zhao, Yong-Li Zheng, Xiao-Na Zhu, Bu-Lang Gao, Gui-Fen Han
{"title":"Morphology and Distribution of Fat Globules in Osteomyelitis on Magnetic Resonance Imaging.","authors":"Li-Yuan Xie, Lei Cao, Wen-Juan Wu, Ji-Cun Liu, Na Zhao, Yong-Li Zheng, Xiao-Na Zhu, Bu-Lang Gao, Gui-Fen Han","doi":"10.2174/0115734056331041250116092101","DOIUrl":"10.2174/0115734056331041250116092101","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this study was to investigate the morphology and distribution characteristics of fat globules in osteomyelitis on magnetic resonance imaging (MRI).</p><p><strong>Materials and methods: </strong>Patients with pathologically-confirmed osteomyelitis and MRI scans were retrospectively enrolled, and fat globules on the MRI images were analyzed.</p><p><strong>Results: </strong>Among 103 patients with non-traumatic osteomyelitis, 75 were fat globule negative and 28 were positive. There was no statistically significant difference in age and gender between patients with and without fat globules (p>0.05). The inflammatory indicators (CRP, ESR, WBC, and NEUT) in the fat globule positive group were significantly higher (p<0.05) than those in the negative group. The lesions were mainly located in the long bones of the limbs in patients with positive fat globules. Twenty-eight patients (27.2% or 28/103) were detected to have fat globules on MRI images, including 20 males (71%) and 8 females (29%) aged 5-64 years (mean 16 years). The time from onset to MRI examination was 8 days to 4 months. The location of fat globules was in the tibia in 10 patients (35.7%), femur in 8 (28.6%), humerus in 4 (14.3%), radius in 2 (7.1%), ulna in 1 (3.6%), calcaneus in 1 (3.6%), sacrum in 1 (3.6%), and fibula in 1 patient (3.6%). On MRI imaging, 28 cases (100%) showed widely distributed patches or tortuous and sinuous abnormal signals in the bone marrow. In 25 cases (89.2%), a grid-like abnormal signal was found in the subcutaneous soft tissue. In 21 patients (75%), pus was found in the adjacent extraosseous soft tissues. Among 28 patients with fat globules, 17 patients (60.7%) had fat globules only in the adjacent extraosseous soft tissue, 6 patients (21.4%) had only intraosseous fat globules [including 5 cases with halo signs around the fat globules and 1 case (3.6%) with fat globules located at the edge of the pus cavity inside the bone without a halo sign], and 5 patients (17.8%) had both intraosseous and extraosseous fat globules. Of 6 patients (21.4% or 6/28) with liquid levels, the liquid level appeared outside the bone.</p><p><strong>Conclusion: </strong>The appearance of fat globules on MRI in patients with osteomyelitis indicates severe infection. Fat globules of osteomyelitis may present with diverse shapes inside and outside the bone marrow as one of the MRI signs of osteomyelitis, with a probability of approximately 27.2%. They have high specificity in diagnosing osteomyelitis and can be used for diagnosis and differential diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056331041"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence for Detecting Pulmonary Embolisms via CT: A Workflow-oriented Implementation. 通过CT检测肺栓塞的人工智能:一个面向工作流程的实现。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056367860250630072749
Selim Abed, Klaus Hergan, Jan Dörrenberg, Lucas Brandstetter, Marcus Lauschmann
{"title":"Artificial Intelligence for Detecting Pulmonary Embolisms <i>via</i> CT: A Workflow-oriented Implementation.","authors":"Selim Abed, Klaus Hergan, Jan Dörrenberg, Lucas Brandstetter, Marcus Lauschmann","doi":"10.2174/0115734056367860250630072749","DOIUrl":"10.2174/0115734056367860250630072749","url":null,"abstract":"<p><strong>Introduction: </strong>Detecting Pulmonary Embolism (PE) is critical for effective patient care, and Artificial Intelligence (AI) has shown promise in supporting radiologists in this task. Integrating AI into radiology workflows requires not only evaluation of its diagnostic accuracy but also assessment of its acceptance among clinical staff.</p><p><strong>Objective: </strong>This study aims to evaluate the performance of an AI algorithm in detecting pulmonary embolisms (PEs) on contrast-enhanced computed tomography pulmonary angiograms (CTPAs) and to assess the level of acceptance of the algorithm among radiology department staff.</p><p><strong>Methods: </strong>This retrospective study analyzed anonymized computed tomography pulmonary angiography (CTPA) data from a university clinic. Surveys were conducted at three and nine months after the implementation of a commercially available AI algorithm designed to flag CTPA scans with suspected PE. A thoracic radiologist and a cardiac radiologist served as the reference standard for evaluating the performance of the algorithm. The AI analyzed 59 CTPA cases during the initial evaluation and 46 cases in the follow-up assessment.</p><p><strong>Results: </strong>In the first evaluation, the AI algorithm demonstrated a sensitivity of 84.6% and a specificity of 94.3%. By the second evaluation, its performance had improved, achieving a sensitivity of 90.9% and a specificity of 96.7%. Radiologists' acceptance of the AI tool increased over time. Nevertheless, despite this growing acceptance, many radiologists expressed a preference for hiring an additional physician over adopting the AI solution if the costs were comparable.</p><p><strong>Discussion: </strong>Our study demonstrated high sensitivity and specificity of the AI algorithm, with improved performance over time and a reduced rate of unanalyzed scans. These improvements likely reflect both algorithmic refinement and better data integration. Departmental feedback indicated growing user confidence and trust in the tool. However, many radiologists continued to prefer the addition of a resident over reliance on the algorithm. Overall, the AI showed promise as a supportive \"second-look\" tool in emergency radiology settings.</p><p><strong>Conclusion: </strong>The AI algorithm demonstrated diagnostic performance comparable to that reported in similar studies for detecting PE on CTPA, with both sensitivity and specificity showing improvement over time. Radiologists' acceptance of the algorithm increased throughout the study period, underscoring its potential as a complementary tool to physician expertise in clinical practice.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056367860"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Evaluation of Submandibular Fossa Depth in Relation to Mandibular Canal and Bone Thickness: CBCT-based Study. 基于cbct的下颌下窝深度与下颌管及骨厚关系的回顾性评价。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056386043250730170653
Hasret Tanrıverdi Şahan, Mehmet Emin Doğan, Esin Akol Görgün
{"title":"Retrospective Evaluation of Submandibular Fossa Depth in Relation to Mandibular Canal and Bone Thickness: CBCT-based Study.","authors":"Hasret Tanrıverdi Şahan, Mehmet Emin Doğan, Esin Akol Görgün","doi":"10.2174/0115734056386043250730170653","DOIUrl":"10.2174/0115734056386043250730170653","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to determine the depth of the SF, bone thicknesses in the buccal and lingual areas of the mandibular canal (MC), vertical positions of the SF and MC relative to each other, and the tooth level at which the deepest point of the SF was observed in the cross-sectional section.</p><p><strong>Methods: </strong>440 cone beam computed tomography (CBCT) images were retrospectively evaluated. The depth of the SF was determined. The buccal bone thickness (BBT) and lingual bone thickness (LBT) of the MC were measured, and the tooth alignment of the deepest point of the SF and the vertical position of the SF and MC relative to each other were determined.</p><p><strong>Results: </strong>In both jaws, SF depth Type I ratios were lower in males than in females, and SF depth Type III ratios were higher than in females. When the relationship between the vertical position of the MC and the region where the SF was deepest was examined, it was observed that the MC was in an inferior position in most patients.</p><p><strong>Discussion: </strong>In order to reduce the complication rate in the SF region, the relevant region should be analyzed in detail with CBCT before surgical procedures. The main limitation of our study is that the number of men and women was not equal.</p><p><strong>Conclusion: </strong>SF depth and BBT values in the right and left jaws were higher in males than in females. LBT was higher in females in the right jaw. As the depth of the SF increased, BBT and LBT values decreased.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056386043"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and Imaging Characteristics of Non-Gestational Ovarian Choriocarcinoma: A Case Report. 非妊娠期卵巢绒毛膜癌的临床与影像学特征1例。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056386021250520043409
Xiaofeng Fu, Wei Chen, Jiang Zhu
{"title":"Clinical and Imaging Characteristics of Non-Gestational Ovarian Choriocarcinoma: A Case Report.","authors":"Xiaofeng Fu, Wei Chen, Jiang Zhu","doi":"10.2174/0115734056386021250520043409","DOIUrl":"10.2174/0115734056386021250520043409","url":null,"abstract":"<p><strong>Background: </strong>Non-gestational Ovarian Choriocarcinoma (NGOC) is an extremely rare and highly malignant ovarian germ cell tumor with nonspecific clinical manifestations, making early diagnosis challenging. At present, detailed reports on the clinical and imaging characteristics of NGOC are scarce. This case report discusses a rare instance of NGOC in a prepubertal adolescent, complemented by a literature review to enhance clinicians' understanding of its presentation, diagnosis, and treatment.</p><p><strong>Case presentation: </strong>A 10-year-old female with no history of menstruation or sexual activity presented with persistent lower abdominal pain and vaginal bleeding. Preoperative imaging revealed a large pelvic mass with heterogeneous echogenicity and vascularity. Serum Human Chorionic Gonadotropin (hCG) levels were markedly elevated (>297,000 IU/L).\u0000\u0000Preoperative Imaging: Ultrasonography and CT demonstrated a large, heterogeneous, hypervascular adnexal mass with features of necrosis and cystic changes, suggesting malignancy.\u0000\u0000Surgical and Pathological Findings: The mass, originating from the right adnexa, was removed via laparotomy. Histopathology confirmed NGOC, supported by immunohistochemistry, showing strong positivity for markers like CD146, CK18, HCG, and HPL, along with a high Ki-67 index (>90%).</p><p><strong>Conclusion: </strong>In young females with no sexual life, significantly elevated HCG levels and imaging findings of a large heterogeneous adnexal mass should raise suspicion for NGOC. Early recognition and multimodal diagnostic approaches, including imaging, biochemical, and pathological assessments, are essential for timely intervention, reducing metastatic risk and improving prognosis. This report contributes to the understanding of NGOC and emphasizes the importance of accurate diagnosis for better patient outcomes.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056386021"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advantages of Multidetector-Row Computed Tomography for Detecting Transverse Mesocolic Internal Hernia 多排探测器计算机断层扫描检测横切性肠系膜内疝的优势。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056359062250414074213
Le Duc Nam, Thai Khac Trong, Nguyen Van Thach, Le Duy Dung, Lam Sao Mai, Tong Thi Thu Hang
{"title":"Advantages of Multidetector-Row Computed Tomography for Detecting Transverse Mesocolic Internal Hernia","authors":"Le Duc Nam, Thai Khac Trong, Nguyen Van Thach, Le Duy Dung, Lam Sao Mai, Tong Thi Thu Hang","doi":"10.2174/0115734056359062250414074213","DOIUrl":"10.2174/0115734056359062250414074213","url":null,"abstract":"<p><strong>Introduction: </strong>A transverse mesocolic internal hernia is a phenomenon in which a small intestinal loop protrudes through the natural orifice in the transverse colon mesentery. This type of internal hernia in adults, although rare, is one of the causes of closed-loop intestinal obstruction, which requires prompt diagnosis and treatment.</p><p><strong>Case presentation: </strong>We report two cases of transverse mesocolic internal hernia that were examined and subsequently treated at Hospital 108, Hanoi, Vietnam. Both patients (53 and 66 years old) had atypical clinical symptoms, mainly dull epigastric pain. Upon admission, they were initially examined clinically, followed by blood testing and chest and abdominal X-ray radiography. Diagnostic imaging was mainly based on subsequent Multidetector-Row Computed Tomography (MDCT). Laparoscopic/surgical release of the hernia and closure of the natural orifice in the transverse colon mesentery were performed. The clinical symptoms and laboratory and radiographic findings did not suggest a causal diagnosis. However, MDCT provided several images suggestive of an internal hernia, including a closed intestinal loop passing through the transverse colon mesentery and located posteriorly in the left abdominal cavity near the Treitz angle, displacement of the mesenteric vascular bundle, and colon displacement. These displacements were the causes of intestinal inflammation/obstruction. Additionally, laparoscopic/surgical results confirmed the MDCT diagnosis.</p><p><strong>Conclusion: </strong>Thin-slice thickness, high spatial resolution, multiplanar reconstruction MDCT was effective for diagnosing transverse mesocolic internal hernia. In our two cases, MDCT helped determine the cause and assess the state of intestinal ischemia.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056359062"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated Brain Tumor segmentation using hybrid YOLO and SAM. 混合YOLO和SAM的自动脑肿瘤分割。
IF 1.1 4区 医学
Current Medical Imaging Reviews Pub Date : 2025-01-01 DOI: 10.2174/0115734056392711250718201911
M Jeyaraj Paul, M Senthil Kumar
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