Current Medical Imaging Reviews最新文献

{"title":"Morphology and Distribution of Fat Globules in Osteomyelitis on Magnetic Resonance Imaging.","authors":"Li-Yuan Xie, Lei Cao, Wen-Juan Wu, Ji-Cun Liu, Na Zhao, Yong-Li Zheng, Xiao-Na Zhu, Bu-Lang Gao, Gui-Fen Han","doi":"10.2174/0115734056331041250116092101","DOIUrl":"10.2174/0115734056331041250116092101","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this study was to investigate the morphology and distribution characteristics of fat globules in osteomyelitis on magnetic resonance imaging (MRI).</p><p><strong>Materials and methods: </strong>Patients with pathologically-confirmed osteomyelitis and MRI scans were retrospectively enrolled, and fat globules on the MRI images were analyzed.</p><p><strong>Results: </strong>Among 103 patients with non-traumatic osteomyelitis, 75 were fat globule negative and 28 were positive. There was no statistically significant difference in age and gender between patients with and without fat globules (p>0.05). The inflammatory indicators (CRP, ESR, WBC, and NEUT) in the fat globule positive group were significantly higher (p<0.05) than those in the negative group. The lesions were mainly located in the long bones of the limbs in patients with positive fat globules. Twenty-eight patients (27.2% or 28/103) were detected to have fat globules on MRI images, including 20 males (71%) and 8 females (29%) aged 5-64 years (mean 16 years). The time from onset to MRI examination was 8 days to 4 months. The location of fat globules was in the tibia in 10 patients (35.7%), femur in 8 (28.6%), humerus in 4 (14.3%), radius in 2 (7.1%), ulna in 1 (3.6%), calcaneus in 1 (3.6%), sacrum in 1 (3.6%), and fibula in 1 patient (3.6%). On MRI imaging, 28 cases (100%) showed widely distributed patches or tortuous and sinuous abnormal signals in the bone marrow. In 25 cases (89.2%), a grid-like abnormal signal was found in the subcutaneous soft tissue. In 21 patients (75%), pus was found in the adjacent extraosseous soft tissues. Among 28 patients with fat globules, 17 patients (60.7%) had fat globules only in the adjacent extraosseous soft tissue, 6 patients (21.4%) had only intraosseous fat globules [including 5 cases with halo signs around the fat globules and 1 case (3.6%) with fat globules located at the edge of the pus cavity inside the bone without a halo sign], and 5 patients (17.8%) had both intraosseous and extraosseous fat globules. Of 6 patients (21.4% or 6/28) with liquid levels, the liquid level appeared outside the bone.</p><p><strong>Conclusion: </strong>The appearance of fat globules on MRI in patients with osteomyelitis indicates severe infection. Fat globules of osteomyelitis may present with diverse shapes inside and outside the bone marrow as one of the MRI signs of osteomyelitis, with a probability of approximately 27.2%. They have high specificity in diagnosing osteomyelitis and can be used for diagnosis and differential diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056331041"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of Cervical Cancer Image Processing and Detection Based on URCNNs.","authors":"Cheng Cheng, Yi Yang, Youshan Qu","doi":"10.2174/0115734056333197241211162651","DOIUrl":"10.2174/0115734056333197241211162651","url":null,"abstract":"<p><strong>Background: </strong>Cervical cancer is a prevalent malignancy among women, often asymptomatic in early stages, complicating detection.</p><p><strong>Objective: </strong>This study aims to investigate innovative techniques for early cervical cancer detection using a novel U-RCNNS model.</p><p><strong>Methods: </strong>Cervical epithelial cell images stained with hematoxylin and eosin (HE) were analyzed using the U-RCNNS model, which integrates U-Net for segmentation and R-CNN for object detection, incorporating dilated convolution techniques.</p><p><strong>Results: </strong>The U-RCNNS model significantly improved the accuracy of detecting and segmenting cervical cancer cells, with the enhanced Mask R-CNN showing notable advancements over the baseline model.</p><p><strong>Conclusion: </strong>The U-RCNNS model presents a promising solution for early cervical cancer detection, offering improved accuracy compared to traditional methods and highlighting its potential for clinical application in early diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056333197"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Features and Ultrasonographic Manifestations of Retroperitoneal Nerve Sheath Tumors.","authors":"Xiaoqing Wang, Xiaoying Zhang, Rui Zhao, Yan Liu, Chaoyang Wen, Haining Zheng","doi":"10.2174/0115734056348636241213120140","DOIUrl":"10.2174/0115734056348636241213120140","url":null,"abstract":"<p><strong>Objectives: </strong>Retroperitoneal nerve sheath tumors are uncommon, representing a small fraction of all primary retroperitoneal neoplasms. Accurate differentiation between benign and malignant forms is essential for optimal clinical management. This study assessed the clinical profiles and sonographic traits of retroperitoneal nerve sheath tumors with the goal of enhancing diagnostic precision and developing therapeutic strategies.</p><p><strong>Methods: </strong>A retrospective analysis of patients diagnosed with benign retroperitoneal nerve sheath tumors who completed surgical treatment and underwent ultrasound imaging was carried out. Tumors were classified based on sonographic features and blood flow characteristics as per Adler's grading system. Statistical analysis was performed using SPSS 25.0. ROC curve analysis was carried out to determine the optimal diagnostic cutoff values.</p><p><strong>Results: </strong>A total of 49 patients were included in the study. There were no significant variances in age, gender, or tumor localization among the groups. However, pronounced disparities were observed in tumor number, size, shape, definition of borders, internal echo pattern, structural composition, presence of calcification, and blood flow signals between the classic and malignant groups. Notably, malignant tumors tended to manifest as larger masses with indistinct margins and irregular shapes. The maximum tumor diameter emerged as a discriminating factor for malignancy, with a diagnostic cutoff of 9.9 cm, yielding an AUC of 0.754 from the ROC curve analysis.</p><p><strong>Conclusion: </strong>This study outlines the distinctive clinical and sonographic features of retroperitoneal nerve sheath tumors, with a particular focus on malignant subtypes. Ultrasonography emerges as a valuable diagnostic tool, contributing to the differentiation of tumor categories and potentially to the development of targeted treatment strategies. The identification of specific sonographic markers may facilitate the early detection and detailed characterization of these tumors, which could contribute to improved patient outcomes.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056348636"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging and Clinical Features of Primary Thoracic Lymphangioma","authors":"Mingxia Zhang, Ling Li, Meng Huo, Lei Sun, Chunyan Zhang, Ying Sun, Rengui Wang","doi":"10.2174/0115734056346925241226125948","DOIUrl":"10.2174/0115734056346925241226125948","url":null,"abstract":"<p><strong>Background: </strong>Primary thoracic lymphangioma is a rare disease. Most of the previous studies are comprised of individual case reports, with a very limited number of patients included.</p><p><strong>Objective: </strong>This study aims to investigate the chest computed tomography (CT) imaging features and clinical manifestations of thoracic lymphangioma, thereby enhancing our understanding of the condition.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 62 patients diagnosed with thoracic lymphangioma, comprising 32 males and 30 females. The study focused on analyzing the chest CT imaging features and the clinical manifestations observed in these patients.</p><p><strong>Results: </strong>The incidence rates of thoracic lymphangioma did not differ significantly between males and females; however, it was more frequently observed in children and adolescents. The most common clinical symptoms included cough, fever, chylothorax, chylous pericardium, and lymphedema. The mediastinum (82.3%) emerged as the most frequent location for thoracic lymphangioma, followed by the chest wall (62.9%), bone (40.3%), and pleura (32.3%). Pulmonary lymphangioma, the least prevalent subtype (19.4%), exhibited a propensity to induce respiratory symptoms, frequently manifesting as a generalized lymphatic anomaly (GLA). Furthermore, elevated levels of D-dimer were detected in 34 patients (54.8%) with thoracic lymphangioma.</p><p><strong>Conclusions: </strong>Imaging examinations play a crucial role in assisting clinicians in making more accurate early diagnoses of thoracic lymphangioma. They are also helpful for assessing the extent of systemic infiltration and enhancing diagnostic precision. With radiological assessment, clinicians could more readily select appropriate therapeutic treatments and monitor the progression of follow-up care.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056346925"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perforated Meckel's Diverticulum in an Adult that Resembles Acute Appendicitis: A Case Report and Review of the Literature.","authors":"Noha Bakhsh, Mai Banjar","doi":"10.2174/0115734056320557241211115403","DOIUrl":"10.2174/0115734056320557241211115403","url":null,"abstract":"<p><strong>Background: </strong>Perforation is one of the rarest effects of Meckel's diverticulum and may clinically resemble acute appendicitis.</p><p><strong>Case report: </strong>A 34-year-old woman with pain in the right iliac fossa, nausea, and vomiting for three days was brought to the emergency department. An abdominal examination indicated rebound tenderness in the area of the right iliac fossa. Abdominal ultrasound showed a heterogeneous lesion in the left iliac fossa measuring 5 cm × 3.5 cm × 4 cm with no internal vascularity. Abdominal Computed Tomography (CT) demonstrated a hypodense lesion located left of the midline of the abdomen, which was inseparable from the small bowel at the antimesenteric border. Laparoscopic exploration was performed, and an intraoperative diagnosis of perforated Meckel's diverticulum with phlegmon formation was made. The patient had an uneventful recovery.</p><p><strong>Conclusion: </strong>Radiologists should be aware of the possibility of complicated Merkel's diverticulum when encountering cases of acute abdominal pain. If there is a lower abdominal inflammatory process and a normal appendix is identified, there should be a high degree of suspicion when examining the CT scan.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value of Using Quantitative MRI based on Synthetic Acquisition and Apparent Diffusion Coefficient to Monitor Multiple Sclerosis Lesion Activity.","authors":"Abdullah H Abujamea, Fahad B Albadr, Arwa M Asiri","doi":"10.2174/0115734056343086250103020830","DOIUrl":"10.2174/0115734056343086250103020830","url":null,"abstract":"<p><strong>Background: </strong>Multiple sclerosis (MS) is one of the most common disabling central nervous system diseases affecting young adults. Magnetic resonance imaging (MRI) is an essential tool for diagnosing and following up multiple sclerosis. Over the years, many MRI techniques have been developed to improve the sensitivity of MS disease detection. In recent years synthetic MRI (sMRI) and quantitative MRI (qMRI) have gained traction in neuroimaging applications, providing more detailed information than traditional acquisition methods. These techniques enable the detection of microstructural changes in the brain with high sensitivity and robustness to inter-scanner and inter-observer variability. This study aims to evaluate the feasibility of using these techniques to avoid administering intravenous gadolinium-based contrast agents (GBCAs) for assessing MS disease activity and monitoring.</p><p><strong>Materials and methods: </strong>Forty-two known MS patients, aged 20 to 45, were scanned as part of their routine follow-up. MAGnetic resonance image Compilation (MAGiC) sequence, an implementation of synthetic MRI, was added to our institute's routine MS protocol to automatically generate quantitative maps of T1, T2, and PD. T1, T2, PD, and apparent diffusion coefficient (ADC) data were collected from regions of interest (ROIs) representing normalappearing white matter (NAWM), enhancing, and non-enhancing MS lesions. The extracted information was compared, and statistically analyzed, and the sensitivity and specificity were calculated.</p><p><strong>Results: </strong>The mean R1 (the reciprocal of T1) value of the non-enhancing MS lesions was 0.694 s-1 (T1=1440 ms), for enhancing lesions 1.015 s-1 (T1=985ms), and for NAWM 1.514 s-1 (T1=660ms). For R2 (the reciprocal of T2) values, the mean value was 6.816 s-1 (T2=146ms) for nonenhancing lesions, 8.944 s-1 (T2=112 ms) for enhancing lesions, and 1.916 s-1 (T2=522 ms) for NAWM. PD values averaged 93.069% for nonenhancing lesions, 82.260% for enhancing lesions, and 67.191% for NAWM. For ADC, the mean value for non-enhancing lesions was 1216.60×10-6 mm2/s, for enhancing lesions 1016.66×10-6 mm2/s, and for NAWM 770.51×10-6 mm2/s.</p><p><strong>Discussion: </strong>Our results indicate that enhancing and non-enhancing MS lesions significantly decrease R1 and R2 values. Non-enhancing lesions have significantly lower R1 and R2 values compared to enhancing lesions.</p><p><strong>Conclusion: </strong>Conversely, PD values are significantly higher in non-enhancing lesions than in enhancing lesions. For ADC, while NAWM has lower values, there was minimal difference between the mean ADC values of enhancing and non-enhancing lesions.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056343086"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sonographic Features of Juvenile Fibroadenoma in Children-a Retrospective Study.","authors":"Jian Shi, Luzeng Chen, Jingming Ye, Shuang Zhang, Hong Zhang, Yuhong Shao, Xiuming Sun","doi":"10.2174/0115734056339987250116102211","DOIUrl":"10.2174/0115734056339987250116102211","url":null,"abstract":"<p><strong>Aims: </strong>Studies specifically examining the sonographic features of juvenile fibroadenoma in the pediatric population have not been documented. We aimed to analyze sonograms of juvenile fibroadenoma in children.</p><p><strong>Subjects and methods: </strong>Patients aged ≤ 18 years who underwent breast ultrasound examinations at our department and had pathologically proven juvenile fibroadenoma from September 2002 to January 2022 were included in this study. Demographic data, clinical findings, and sonograms were retrospectively analyzed. Patients were further divided into the puberty and post-puberty subgroups, and their results were compared.</p><p><strong>Results: </strong>A total of 24 girls aged 10-18 years with 27 masses diagnosed as juvenile fibroadenomas were identified. The diameter of the masses averaged 5.8 ± 3.3 cm, with a range of 1.5-13.6 cm. Twenty-one (87.5%) patients had a single mass and 3 had double lesions. Over 80% of the lesions were oval-shaped and encapsulated with circumscribed margins and parallel orientation. All masses showed internal hypoechogenicity, either uniform or heterogeneous. For masses that had a diameter > 5 cm, screening with high-frequency transducers revealed no posterior acoustic features or posterior shadowing. However, these features changed to posterior acoustic enhancement when the masses were re-evaluated using low-frequency transducers. Ultrasonic color Doppler showed blood flow in 24 (88.9%) masses. There were no significant differences in the incidence and sonographic features between the two subgroups.</p><p><strong>Conclusion: </strong>Most juvenile fibroadenomas in children are oval, circumscribed, encapsulated masses with detectable blood flow. All juvenile fibroadenomas presented in this study exhibit internal hypoechogenicity with no posterior acoustic shadowing detected in any cases. Our findings suggest that screening with low-frequency transducers should be performed for a mass that has a diameter > 5 cm.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056339987"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Prostate MR Image and Predictive Value for Benign Prostate Disease among Different DWI Sequences.","authors":"Hanli Dan, Lu Yang, Yuchuan Tan, Yipeng Zhang, Yong Tan, Jing Zhang, Min Li, Meng Lin, Jiuquan Zhang","doi":"10.2174/0115734056329976241209112720","DOIUrl":"10.2174/0115734056329976241209112720","url":null,"abstract":"<p><strong>Background: </strong>Early diagnosis of prostate cancer can improve the survival rate of patients on the premise of high-quality images. The prerequisite for early diagnosis is high-quality images. ZOOMit is a method for high-resolution, zoomed FOV imaging, allowing diffusion-weighted images with high contrast and resolution in short acquisition times. RESOLVE DWI is an advanced MRI technique developed to obtain high-resolution diffusionweighted images with reduced susceptibility-related artifacts.</p><p><strong>Objective: </strong>This study aimed to compare the image quality of conventional single-shot Echo-planar Imaging (ss-EPI), Diffusion-weighted Imaging (DWI), zoomed FOV imaging (ZOOMit) DWI, and readout segmentation of long variable echo-trains (RESOLVE) DWI sequences for prostate imaging, and optimize the strategy to obtain high-quality Magnetic Resonance Imaging (MRI) in order to discriminate malignant and benign prostate diseases.</p><p><strong>Methods: </strong>Fifty-one patients were enrolled, including 31 with prostate cancer, 11 with prostate benign disease, and 9 with bladder cancer. Patients underwent MRI scans using T2-weighted (T2W), ss-EPI DWI, ZOOMit DWI, and RESOLVE DWI (b = 0, 50, 1400 s/mm2) sequences using a 3.0T MRI scanner. Subjective scores of image quality were evaluated by two independent radiologists. Differences in the subjective scores and objective parameters among the three sequences were compared. The agreement and consistency between the findings of the two raters were evaluated with Kappa or Intra-class Correlation Coefficient (ICC). Receiver Operating Characteristic (ROC) curves were used to distinguish malignant and benign prostate disease.</p><p><strong>Results: </strong>The agreement of subjective scores of 51 patients was high or moderate between the two radiologists (kappa: 0.529-0.880). ZOOMit displayed the highest clarity and the lowest distortion and artifacts compared to ss-EPI and RESOLVE. The two radiologic technicians obtained moderate or high consistency of objective measurement (ICC: 0.527-0.924). In the ROC analysis, ADCmean and Prostate Imaging Reporting and Data System (PI-RADS) scores for three sequences were comparable in differentiating prostate cancer from benign prostate disease (all p>0.05), in which ZOOMit indicated the highest Area Under the Curve (AUC) (0.930 and 0.790, respectively).</p><p><strong>Conclusion: </strong>Compared to the other two sequences, ZOOMit can be deemed preferable to improve prostate MRI diffusion imaging as it has exhibited the highest AUC in identifying prostate cancer.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance and Predictive Value of Delphian Lymph Node in Papillary Thyroid Carcinoma.","authors":"Yaqi Cui, Yimeng Li, Xinlu Yin, Jiadong Wang","doi":"10.2174/0115734056360214250215155608","DOIUrl":"10.2174/0115734056360214250215155608","url":null,"abstract":"<p><strong>Background: </strong>Delphian lymph node (DLN) metastasis is common in papillary thyroid cancer (PTC). However, few studies have specifically investigated the clinicopathologic characteristics of DLN metastasis in PTC. This study aimed to examine the incidence, risk factors, and predictive value of DLN in papillary thyroid carcinoma.</p><p><strong>Methods: </strong>In the present study, the clinicopathologic features and metastatic risks were statistically analyzed by reviewing 1837 patients with papillary thyroid carcinoma who underwent initial surgery in our department between January, 2022 and July, 2024.</p><p><strong>Results: </strong>Among the 1837 patients included in the study, DLN was detected in 925 patients (50.3%), of which 409 patients (22.3%) had confirmed DLN metastasis. In univariate analysis, DLN metastasis was correlated with age (≥55 years), bilateral cancer, multifocality, tumor location (isthmus cancer), central lymph node metastasis (CLNM), and lateral lymph node metastasis (LLNM). However, it was not correlated with gender distribution, tumor size, thyroiditis, thyroid-stimulating hormone (TSH) level, and BRAF mutation. Multivariate analysis showed that CLNM (p=0.03), LLNM (p=0.025), bilateral cancer, and tumor location (p=0.012) were independent risk factors for DLN metastasis. DLN involvement was mildly predictive of CLNM (sensitivity=29.76%, specificity=87.06%, positive predictive values=74.08%, negative predictive values=49. 93%, positive likelihood ratio=2.30, negative likelihood ratio=0.81) and moderately predictive of LLNM (sensitivity=49.36%, specificity=85.01%, positive predictive values=46.94%, negative predictive values=86.20%, positive likelihood ratio=3.29, negative likelihood ratio=0.60).</p><p><strong>Conclusion: </strong>Bilateral cancer, CLNM, LLNM, and isthmus cancer were independent risk factors for DLN metastasis. DLN metastasis could be used as a predictor for central and lateral lymph node metastasis. Positive DLN should be a warning signal to carefully evaluate central and lateral lymph nodes during thyroidectomy.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":"e15734056360214"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Diagnostic Accuracy in Acute Pulmonary Embolism: Insights from Spectral Dual-energy CT.","authors":"Mei-Ling Shen, Han-Wen Zhang, Li-Hong Liu, Wei-Ming Liu, Hua Zhong, Biao Huang, Yu-Li Wang, Fan Lin","doi":"10.2174/0115734056323974241202175740","DOIUrl":"10.2174/0115734056323974241202175740","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to evaluate the clinical efficacy of spectral dual-energy detector computed tomography (SDCT) and its associated parameters in diagnosing acute pulmonary embolism (APE).</p><p><strong>Methods: </strong>Retrospective analysis of imaging data from 86 APE-diagnosed patients using SDCT was conducted. Virtual monoenergetic images (VMIs) at 40, 70, and 100 KeV, Iodine concentration (IC) maps, Electron Cloud Density Map (ECDM), Effective atomic number (Z-eff) maps, and Hounsfield unit attenuation plots (VMI slope) were reconstructed from pulmonary artery phase CT images. The subtraction (SUB) and ratios of VMIs were calculated, and two experienced radiologists evaluated the patients. The Mann-Whitney U test assessed the parameter ability to differentiate between normal and obstructed lung fields and detect emboli in the pulmonary artery. Receiver Operating Characteristic Curves (ROC) were generated for performance evaluation.</p><p><strong>Results: </strong>Significant differences (p<0.001) in 40KeV, Ratio, SUB, and Z-eff were found between normal and embolized lung fields. Logistic regression demonstrated good detection performance for Z-eff (AUC=0.986), SUB (AUC=0.975), and IC (AUC=0.974). Parameters such as 40KeV (AUC=0.990), 70KeV (AUC=0.980), 100KeV (AUC=0.962), SUB (AUC=0.990), Z-eff (AUC=0.999), and IC (AUC=1.000) exhibited good detection capabilities for identifying emboli in the pulmonary artery.</p><p><strong>Conclusion: </strong>SDCT facilitates the identification of diseased lung fields and localization of emboli in the pulmonary artery, thereby improving diagnostic efficiency in APE.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}