Anish Bhandari, Mark Greenhill, Mayra Anthony, Sorabh Sharma, Raza Mushtaq
{"title":"MRI Imaging Appearance of Hyperostosis Frontalis Interna (HFI): A Case Report of Focal Benign Enhancement.","authors":"Anish Bhandari, Mark Greenhill, Mayra Anthony, Sorabh Sharma, Raza Mushtaq","doi":"10.2174/1573405620666230720103113","DOIUrl":"10.2174/1573405620666230720103113","url":null,"abstract":"<p><strong>Introduction: </strong>Hyperostosis frontalis interna (HFI) is a common and often incidental finding seen on imaging. There is a significant paucity of radiology literature, particularly regarding the MRI imaging appearance of HFI.</p><p><strong>Case presentation: </strong>We reported two cases of HFI on MRI, which showed focal enhancement. These were stable on long-term follow-up studies and thought to be most consistent with benign enhancement.</p><p><strong>Conclusion: </strong>Further studies are needed to elucidate the underlying pathogenesis; however, it is important to be aware that regions of HFI may demonstrate variable enhancement and are sometimes mistaken for osseous metastatic disease.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9866238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Performance analysis of Alexnet for Classification of Knee Osteoarthritis.","authors":"T Sivakumari, R Vani","doi":"10.2174/1573405620666230809105544","DOIUrl":"10.2174/1573405620666230809105544","url":null,"abstract":"<p><strong>Background: </strong>In recent years, automated grading of knee osteoarthritis (KOA) has focused on determining disease progression. Clinical examinations and radiographic image review are necessary for diagnosis. Timely and accurate diagnosis, along with medical care, can slow down KOA progression. X-rays and MRI are crucial diagnostic tools. KOA diagnosis traditionally relies on radiologists' and clinicians' experience. However, the rapid development of deep learning technology (AI) offers promising solutions for medical applications.</p><p><strong>Objective: </strong>The objective of this study was to review and summarize various methods proposed by researchers for the automated grading of KOA. Additionally, this study aimed to evaluate the performance of the AlexNet model in classifying the severity of KOA. The performance of the AlexNet model has been compared to that of other models, and the results have been assessed.</p><p><strong>Method: </strong>A comprehensive review of existing research on automated grading of KOA has been conducted. Various methods proposed by different researchers have been examined and summarized. The AlexNet model has been employed for classifying the severity of KOA, and its performance has been evaluated. A comparative analysis has been carried out to compare the performance of the AlexNet model with that of other models. The results obtained from the evaluation have been assessed to determine the effectiveness of the AlexNet model in the automated grading of KOA.</p><p><strong>Results: </strong>The results of the study indicate that the AlexNet model demonstrates promising performance in classifying the severity of KOA. Comparative analysis reveals that the AlexNet model outperforms other models in terms of accuracy and efficiency. The evaluation of the model's performance provides valuable insights into the effectiveness of deep learning techniques for automated grading of KOA.</p><p><strong>Conclusion: </strong>This study highlights the significance of automated grading in the diagnosis and management of knee osteoarthritis. The utilization of deep learning technology, particularly the AlexNet model, shows promise in accurately classifying the severity of KOA. The findings suggest that automated grading methods can serve as valuable tools for healthcare professionals in assessing the progression of KOA and providing appropriate medical care. Further research and development in this area can contribute to enhancing the efficiency and accuracy of automated grading systems for KOA.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9969259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Muscle CT Radiomics is Feasible in the Identification of Gout.","authors":"Ye Zeng, Chunlin Xiang, Gang Wu","doi":"10.2174/0115734056313937240816070503","DOIUrl":"10.2174/0115734056313937240816070503","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the feasibility of muscle CT radiomics in identifying gout.</p><p><strong>Materials and methods: </strong>A total of 30 gout patients and 20 non-gout cases with CT examinations of ankles were analyzed by using the methods of CT radiomics. CT radiomics features of the soleus muscle were extracted using the software of a 3D slicer, and then gout cases and non-gout cases were compared. The radiomics features that were significantly different between the two groups were then processed with machine learning methods. Receiver operating characteristic curve analysis was used to evaluate the diagnostic performance.</p><p><strong>Results: </strong>Five CT radiomics features were significantly different between gout cases and non-gout cases (P < 0.05). In the logic regression, the AUC, sensitivity, specificity, and accuracy were 0.738, 77% (46/60), 70% (28/40), and 74% (74/100), respectively. In the Random forest, Xgboost, and support vector machine analysis, the accuracy was 0.901, 0.833, and 0.875, respectively.</p><p><strong>Conclusion: </strong>From this study, it can be concluded that muscle CT radiomics is feasible in identifying gout.</p>.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Value of 3.0 T Magnetic Resonance Imaging in Active Crohn's Disease.","authors":"Li-Li Fu, Xiao-Zhao Zhuang, Chang-Qing Li, Chui-Wen Chen","doi":"10.2174/0115734056267653231129104404","DOIUrl":"https://doi.org/10.2174/0115734056267653231129104404","url":null,"abstract":"<p><strong>Background: </strong>Magnetic resonance enteroclysis (MRE) has been widely applied to diagnose Crohn's disease (CD). Magnetic resonance (MR) at 3.0 T improves signal-to-noise ratio (SNR), shortens image acquisition time, and shows more advantages.</p><p><strong>Objective: </strong>This study aimed to retrospectively analyze the diagnostic value of 3.0 T MR imaging for active CD.</p><p><strong>Methods: </strong>48 CD patients hospitalized in our hospital from January 2021 to December 2022 were selected as the study subjects. These 48 CD patients underwent both double-balloon enteroscopy and 3.0 T MRE. All patients' arterial phase signal, venous phase signal, bowel wall, and bowel lumen of MRE were observed to identify whether they suffered from active CD. Based on the results of enteroscopy, the number of true positives, true negatives, false negatives, and false positives diagnosed by MRE were screened; next, the diagnostic accuracy, sensitivity, and specificity of MRE in assessing active CD were calculated.</p><p><strong>Results: </strong>Of the 48 patients, 39 were diagnosed with small bowel CD by MRE, which was not significantly different from the results of enteroscopy (P>0.05). According to MRE diagnostic results, the arterial phase predominantly presented high signal intensity, and the venous phase mainly presented low signal intensity or isointensity. Small bowel CD lesions were primarily characterized by bowel wall thickening, rare pneumatosis enhancement of the bowel wall, bowel lumen pneumatosis or dilatation, and rare strictures. Besides, MRE presented an accuracy of 93.75%, sensitivity of 97.37%, and specificity of 80.00% in diagnosing CD.</p><p><strong>Conclusion: </strong>3.0 T MR imaging has diagnostic value for active CD and shows certain clinical application value.</P>.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi-Wen Zhang, Dan Wu, Zhen-Zhen Zhu, Jin-Chun Ou, Zhuo-Chao Kong, Wen-Fang Zhu, Qing-Ming Shi, Min Wang
{"title":"Analysis of the Imaging Features and Prognosis of Pulmonary Tuberculosis Complicated with Pulmonary Embolism","authors":"Yi-Wen Zhang, Dan Wu, Zhen-Zhen Zhu, Jin-Chun Ou, Zhuo-Chao Kong, Wen-Fang Zhu, Qing-Ming Shi, Min Wang","doi":"10.2174/1573405620666230331082549","DOIUrl":"10.2174/1573405620666230331082549","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to explore the imaging characteristics of patients with pulmonary tuberculosis complicated with pulmonary embolism and\u0000analyze the prognosis of the condition, thereby reducing the mortality and misdiagnosis rate of complications in this type of pulmonary\u0000tuberculosis.</p><p><strong>Methods: </strong>In this retrospective study, a total of 70 patients diagnosed with pulmonary embolism by computed tomography pulmonary angiography (CTPA)\u0000from January 2016 to May 2021 in Anhui Chest Hospital were included. Among them, 35 patients with pulmonary embolism combined with\u0000pulmonary tuberculosis were set as the study group, and the other 35 patients with pulmonary embolism only were set as the control group. The\u0000imaging findings of chest CT examination, the incidence of pulmonary hypertension, the level of N-terminal proto-B-type brain natriuretic peptide\u0000(NT-proBNP), and the prognosis of patients were compared between the two groups. The incidence of deep venous embolism was evaluated by\u0000ultrasonography of the lower extremity.</p><p><strong>Results: </strong>In the study group, the median age of patients was 71 years, and the ratio of males to females was 2.5 to 1. In the control group, the median age\u0000was 66 years old, and the male-to-female ratio was 2.2 to 1. There were 16 cases (16/35, 45.71%) in the study group and 10 cases (10/35, 28.57%)\u0000in the control group with an increased level of NT-proBNP. Pulmonary hypertension occurred in 10 patients (10/35, 28.57%) in the study group\u0000and 7 patients (7/35, 20.00%) in the control group. Patients who lost follow-up included 5 in the study group (5/35, 14.29%) and 3 in the control\u0000group (3/35, 8.57%). There were 17 cases (17/35, 48.57%) in the study group and 3 cases (3/35, 8.57%) in the control group with pulmonary artery\u0000widening, and the difference was significant (P < 0.001). There were 13 deaths in the study group (13/35, 37.14%) and 1 death in the control group\u0000(1/35, 2.86%), and the difference was significant (P <0.001).</p><p><strong>Conclusion: </strong>Special signs of pulmonary artery widening, pulmonary hypertension of varying degrees, and increased levels of NT-proBNP of varying degrees\u0000can be found in patients with pulmonary tuberculosis complicated with pulmonary embolism, and the three signs are positively correlated. The\u0000mortality of patients with pulmonary tuberculosis complicated with pulmonary embolism is significantly higher than that of patients with\u0000pulmonary embolism alone. Pulmonary tuberculosis and pulmonary embolism both occur in the ipsilateral lung, causing clinical symptoms to\u0000cover each other, thereby making diagnosis difficult.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9220632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ionel-Daniel Nati, Andrei Mihai Malutan, Razvan Ciortea, Carmen Bucuri, Maria Patricia Rada, Cristina Mihaela Ormindean, Dan Mihu
{"title":"Endometriosis Reccurence – is Ultrasound the Solution?","authors":"Ionel-Daniel Nati, Andrei Mihai Malutan, Razvan Ciortea, Carmen Bucuri, Maria Patricia Rada, Cristina Mihaela Ormindean, Dan Mihu","doi":"10.2174/1573405620666230405093304","DOIUrl":"10.2174/1573405620666230405093304","url":null,"abstract":"<p><strong>Background: </strong>Transvaginal and transabdominal ultrasonography has become a widely used investigative method in the diagnostic workup of endometriosis, as\u0000well as for the postoperative follow-up. The variety of lesions, the distorted anatomy caused by adhesions and the fibrosis process represent the\u0000main challenges of the ultrasound evaluation. Regarding the recurrence of endometriosis, the diagnostic criteria are being imprecise, being adjusted\u0000according to the development of ultrasound techniques.</p><p><strong>Objective and methods: </strong>To this study, extensive research has been performed interrogating PubMed, Embase and Web of Science databases to identify published research\u0000including patients with endometriosis who underwent surgery. Included patients had postoperative ultrasound investigations to detect evidence of\u0000endometriosis recurrence. The selected timeframe was 5 years. We conducted a literature review on ultrasound markers of endometriosis\u0000recurrence.</p><p><strong>Results: </strong>In this analysis, 2023 patients from 9 studies were included. The recurrence rate detected was 17.26%. The postoperative treatment was different in\u0000the selected studies and they include the administration of progesterone, oral combined contraceptives, GnRh antagonists, aromatase inhibitors and\u0000intrauterine devices with prolonged release of progesterone.</p><p><strong>Discussion: </strong>The recurrence rate is different in the selected studies as a result of the recurrence definition used by each author and the minimum dimension of\u0000the lesions, in case of the cystic pattern. Innovative techniques of differential diagnosis by ultrasound are proposed, one of them being the textural\u0000analysis performed by computer-aided diagnosis – CAD. In order to standardize the recommendations regarding imaging techniques, we propose\u0000an algorithm for following up with patients in the postoperative period.</p><p><strong>Conclusion: </strong>The transabdominal or endovaginal ultrasound performed regularly represents a key factor to determine the recurrence of endometriosis in the\u0000postoperative period and the imaging reassessment is recommended to be performed at a 6-month interval.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9274458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Establishing Protocol-based Dose Metrics for Common Abdomen and Pelvis Computed Tomography Protocols","authors":"Entesar Zawam Dalah, Jamila Salam Alsuwaidi, Reem Salim AlKtebi, Muna Abdellatif Ali AlMulla, Priyank Gupta","doi":"10.2174/1573405620666230522151357","DOIUrl":"10.2174/1573405620666230522151357","url":null,"abstract":"<p><strong>Background and aim: </strong>The majority of the existing diagnostic reference levels (DRLs) that have been established for computed tomography (CT) are based on various anatomical locations, such as the head, chest, abdomen, etc. However, DRLs are initiated to improve radiation protection by conducting a comparison of similar examinations with similar objectives. The aim of this study was to explore the feasibility of establishing dose baselines based on common CT protocols for patients who underwent enhanced CT abdomen and pelvis exams.</p><p><strong>Methods: </strong>Dose length product total (tDLPs), volumetric CT dose index (CTDIvol), size-specific dose estimate (SSDE), effective dose (E), and scan acquisition parameters for a total of 216 adult patients, who underwent an enhanced CT abdomen and pelvis exams over a one-year period, were obtained and retrospectively analyzed. Spearman coefficient and one-way ANOVA tests were used to check significant differences between dose metrics and the different CT protocols.</p><p><strong>Results: </strong>The data exhibited 9 different CT protocols to acquire an enhanced CT abdomen and pelvis exam at our institute. Out of these, 4 were found more common, i.e., CT protocols were acquired for a minimum of 10 cases. Triphasic liver demonstrated the highest mean and median tDLPs across all 4 CT protocols. Triphasic liver protocol registered the highest E followed by gastric sleeve protocol with a mean of 28.7 and 24.7 mSv, respectively. Significant differences (p < 0.0001) were found between the tDLPs of anatomical location and the CT protocol.</p><p><strong>Conclusion: </strong>Evidently, wide variability exists across CT dose indices and patient dose metrics relying on anatomical-based dose baseline, i.e., DRLs. Patient dose optimizations require establishing dose baselines based on CT protocols rather than the anatomical location.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9505774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Woo Young Kang, Suk-Joo Hong, Ok Hee Woo, Chang Ho Kang, Kyung-Sik Ahn, Baek Hyun Kim, Euddeum Shim
{"title":"T2 Black Synovitis in Musculoskeletal MRI: Disease Spectrum and Imaging Characteristics of Joint Diseases","authors":"Woo Young Kang, Suk-Joo Hong, Ok Hee Woo, Chang Ho Kang, Kyung-Sik Ahn, Baek Hyun Kim, Euddeum Shim","doi":"10.2174/1573405620666230601114534","DOIUrl":"10.2174/1573405620666230601114534","url":null,"abstract":"<p><p>The synovium may be affected by a wide spectrum of disorders, including inflammatory, infectious, degenerative, traumatic, hemorrhagic, and\u0000tumorous conditions. Magnetic resonance imaging (MRI) is a valuable imaging modality to characterize synovial disorders. Most abnormal lesions\u0000appear as areas of nonspecific high signal intensity on T2-weighted images (T2-WI) due to high water content or increased perfusion. However, T2\u0000hypointensity can be attributed to blood components of varying ages, calcification, inorganic crystals, fibrosis, caseous necrosis and/or amyloid\u0000deposition. Hypointense lesions on T2-WI are infrequent and additional clinical and imaging characteristics can help to limit the list of differential\u0000diagnoses, which may include tenosynovial giant cell tumor, synovial chondromatosis, rheumatoid arthritis, tuberculous arthritis, chronic\u0000tophaceous gout, amyloid arthropathy, synovial hemangioma, lipoma arborescens and hemosiderotic synovitis. Recently, susceptibility weighted\u0000imaging has been developed and may contribute to more accurate diagnosis for deoxygenated blood and calcium. We review the MRI features of\u0000hypointense synovial lesions on MRI and emphasize the characteristic findings that suggest a correct diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Survey of Denoising, Segmentation and Classification of Pancreatic Cancer Imaging","authors":"Harjinder Kaur, Sumindar Kaur Saini, Niharika Thakur, Mamta Juneja","doi":"10.2174/1573405620666230515090523","DOIUrl":"10.2174/1573405620666230515090523","url":null,"abstract":"<p><strong>Background: </strong>Pancreatic cancer is one of the most serious problems that has taken many lives worldwide. The diagnostic procedure using the traditional approaches was manual by visually analyzing the large volumes of the dataset, making it time-consuming and prone to subjective errors. Hence the need for the computer-aided diagnosis system (CADs) emerged that comprises the machine and deep learning approaches for denoising, segmentation and classification of pancreatic cancer.</p><p><strong>Introduction: </strong>There are different modalities used for the diagnosis of pancreatic cancer, such as Positron Emission Tomography/Computed Tomography (PET/CT), Magnetic Resonance Imaging (MRI), Multiparametric-MRI (Mp-MRI), Radiomics and Radio-genomics. Although these modalities gave remarkable results in diagnosis on the basis of different criteria. CT is the most commonly used modality that produces detailed and fine contrast images of internal organs of the body. However, it may also contain a certain amount of gaussian and rician noise that is necessary to be preprocessed before segmentation of the required region of interest (ROI) from the images and classification of cancer.</p><p><strong>Method: </strong>This paper analyzes different methodologies used for the complete diagnosis of pancreatic cancer, including the denoising, segmentation and classification, along with the challenges and future scope for the diagnosis of pancreatic cancer.</p><p><strong>Result: </strong>Various filters are used for denoising and image smoothening and filters as gaussian scale mixture process, non-local means, median filter, adaptive filter and average filter have been used more for better results.</p><p><strong>Conclusion: </strong>In terms of segmentation, atlas based region-growing method proved to give better results as compared to the state of the art whereas, for the classification, deep learning approaches outperformed other methodologies to classify the images as cancerous and non- cancerous. These methodologies have proved that CAD systems have become a better solution to the ongoing research proposals for the detection of pancreatic cancer worldwide.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9823908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cemal Çavdarlı, Hülya Güvenç, Sebile Çomçalı, Çiğdem Coşkun, Mehmet Numan Alp
{"title":"Conspicuous Peripheral Retinal Hemorrhages with a Relatively Preserved Posterior Pole in Immune Thrombocytopenic Purpura.","authors":"Cemal Çavdarlı, Hülya Güvenç, Sebile Çomçalı, Çiğdem Coşkun, Mehmet Numan Alp","doi":"10.2174/0115734056270927231123105203","DOIUrl":"10.2174/0115734056270927231123105203","url":null,"abstract":"<p><strong>Background: </strong>Immune thrombocytopenic purpura (ITP) is a rare auto-antibody mediated disease of isolated thrombocytopenia (<100,000/μL) with normal haemoglobin levels and leukocyte counts. Only a small number of ITP cases have been reported with accompanying ophthalmological findings. Herein, we report an ITP case with demonstrative retinal haemorrhages.</p><p><strong>Case presentation: </strong>A fifty-five-year-old woman with a known history of type 2 diabetes mellitus was referred to our clinic with blurred vision. After detailed anamnesis and clinical assessment, she was diagnosed as primary ITP in haematology department, and systemic steroid (1.5mg/kg) therapy was initiated. During her follow-up, a concomitant peripheral facial paralysis (PFP) emerged. In the course of follow-up, her platelet counts increased gradually, the retinal haemorrhages regressed partially, and the PFP recovered completely.</p><p><strong>Conclusion: </strong>ITP is a rare haematologic disease that sometimes manifests with additional systemic involvements, and this disease should be remembered in the differential diagnosis of unusual retinal haemorrhages, which might be the only presenting feature.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}