Revista Peruana de Medicina de Experimental y Salud Publica最新文献

{"title":"Mechanical ventilation, hospitalization time, deaths and disability according to the variants of Guillain-Barré syndrome: systematic review and meta-analysis.","authors":"Silvana Ximena Castro Diaz, Luiza Pereira-Salto, Roger Vladimir Araujo Castillo","doi":"10.17843/rpmesp.2024.413.13509","DOIUrl":"10.17843/rpmesp.2024.413.13509","url":null,"abstract":"<p><strong>Background: </strong>Motivation for the study. It is unclear which variant of Guillain-Barré syndrome is mostly associated with adverse outcomes.</p><p><strong>Background: </strong>Main findings. Variants had longer time in MV (7.42 days longer), and hospitalization (3.11 days longer). By subgroups, we found that children with the axonal variant had a greater use of MV; whereas, the demyelinating variant was more frequent among adults in MV.</p><p><strong>Background: </strong>Implications. Our results could be used for the implementation of new public health policies, allowing health personnel to have a better knowledge of the prognosis of each variant and the necessary resources to face future outbreaks.</p><p><strong>Objectives.: </strong>To determine the requirement and time to mechanical ventilation and Intensive Care Unit (ICU), hospitalization and hospitalization time, death and disability of the axonal variants of Guillain-Barré Syndrome (GBS) in comparison with the acute demyelinating variant in patients of all the ages.</p><p><strong>Materials and methods.: </strong>The systematic review that included patients with GBS. The exposure variable was the axonal variants and the comparator was acute inflammatory demyelinating polyneuropathy (AIDP). The outcomes were the requirement and time on mechanical ventilation (MV), requirement and time in the ICU, hospitalization time, disability and death. The NewCasttle-Ottawa Scale (NOS) was used to assess risk of bias. A meta-analysis was conducted to calculate mean differences and relative risks (RR) with their 95% confidence intervals (CI) using inverse variances and random effects models.</p><p><strong>Results.: </strong>Of the 3116 articles found, 46 met the selection criteria. The time on MV was 7.42 days (95% CI: 0.36 to 1.48) and the hospitalization time was 3.11 (95% CI: 0.73 to 5.49) days for the axonal variants. The axonal variants had a RR of 0.47 (95% CI: 0.24 to 0.92) for the requirement of MV in adults, but it was 1.68 (95% CI: 1.25 to 2.25) in children. There was a high statistical heterogeneity.</p><p><strong>Conclusions.: </strong>Axonal variants showed, on average, longer MV and hospitalization time, overall and by subgroups. A high MV requirement was found for axonal variants in children; it was lower for adults.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"247-258"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexistence and food sources of adult mosquitoes (Diptera: Culicidae) in a rural health center in Piura, Peru 2024.","authors":"Archi Alejandro Ruiz Polo, Leslie Diana Luis Arismendiz, Lourdes Viviana Barrera Rivera, Arturo Alvarado Aldana, Kelina Isbelia Saavedra Cornejo, Jose Pablo Juárez Vilchez","doi":"10.17843/rpmesp.2024.413.13696","DOIUrl":"https://doi.org/10.17843/rpmesp.2024.413.13696","url":null,"abstract":"<p><strong>Background: </strong>Motivation for the study. Rural health facilities could be potential foci of transmission and scenarios of zoonosis during epidemic outbreaks of dengue and other arbovirosis due to the coexistence of mosquito species that feed on different vertebrates.</p><p><strong>Background: </strong>Main findings. Aedes aegypti feeds on Homo sapiens sapiens. Culex quinquefasciatus feeds on Homo sapiens sapiens and Canis familiaris. Both coexist in health care areas of the Querecotillo health center.</p><p><strong>Background: </strong>Implications. Molecular techniques should be integrated into vector control to understand feeding patterns in natural conditions and information on probable reservoirs.</p><p><strong>Background: </strong>This study aimed to determine the coexistence and food sources of adult mosquitoes (Diptera: Culicidae) in a rural health center in Piura, Peru by using a descriptive cross-sectional design. Entomological techniques were used to capture and identify mosquitoes, and molecular biotechnology techniques were used to identify food sources. A total of 793 specimens of the Culex and Aedes genera were found coexisting, 789 (99.5%) were Culex quinquefasciatus, 607 (76.9%) were males and 182 (23.1%) were females. Likewise, 4 (100%) corresponded to Aedes aegypti females. The food sources of Aedes aegypti were Homo sapiens sapiens, and Homo sapiens sapiens and Canis familiaris were the food sources of Culex quinquefasciatus. This study provides evidence that rural health centers could be acting as foci of arbovirosis, with the risk that people who come for different ailments could contract diseases transmitted by C. quinquefasciatus and A. aegypti.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"309-315"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of foodborne diseases in Ecuador.","authors":"Angelica Ochoa-Avilés, Samuel Escandón, Cristina Ochoa-Avilés, Odalys Heredia-Andino, Johana Ortiz-Ulloa","doi":"10.17843/rpmesp.2024.413.13456","DOIUrl":"https://doi.org/10.17843/rpmesp.2024.413.13456","url":null,"abstract":"<p><strong>Background: </strong>Motivation for the study. In Ecuador, foodborne disease (FBD) incidence rates adjusted for population size have not been estimated, which will serve to identify priority geographic areas.</p><p><strong>Background: </strong>Main findings. Between 2015-2020, 113,695 cases of FBD were identified, with \"other food poisoning\" and hepatitis A being most common. The highest incidence rates were found in the Amazon region. There is marked variability by geographic region in the incidence rates during the study period.</p><p><strong>Background: </strong>Public health implications. It is necessary to optimize the registry system, establish detection and treatment protocols, analyze the causes related to the higher incidence of FBD in the Amazon region, and design a health promotion program focused on preventing contamination and establishing diagnostic and treatment protocols.</p><p><strong>Background: </strong>In order to describe the incidence rates per 100 000 population of foodborne disease (FBD) cases during the period 2015-2020 in Ecuador, we carried out a secondary analysis of epidemiological surveillance records and population projections from the National Institute of Statistics and Census. A total of 113,695 cases were reported with an incidence of more than 100 cases per 100 000 population (2015-2019). In 2020, the records are considerably lower than those reported in previous years. Most cases were reported as \"other food poisoning\". The highest incidence rates of FBD were found in the Amazon region. In general, there is a marked annual variability in the incidence of FBD according to the geographic regions of Ecuador. In conclusion, FBD represent a public health problem in Ecuador. Comprehensive preventive strategies should be designed with special emphasis on the Amazon region.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"273-280"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with obsessive-compulsive symptoms in medical students during the COVID-19 pandemic in Peru: a cross-sectional study.","authors":"William Alexander Barzola-Farfán, Juan Carlos Ocampo-Zegarra","doi":"10.17843/rpmesp.2024.413.13592","DOIUrl":"https://doi.org/10.17843/rpmesp.2024.413.13592","url":null,"abstract":"<p><strong>Background: </strong>Motivation for the study. The COVID-19 pandemic contributed to the development of mental disorders among medical students, including obsessive-compulsive symptoms. However, evidence on this problem in this population is still limited.</p><p><strong>Background: </strong>Main findings. One in 10 medical students presented clinically significant obsessive-compulsive symptoms.</p><p><strong>Background: </strong>Implications. The health crisis has had a negative impact on the mental health of medical students. Therefore, it is crucial to implement future interventions to promote the preservation of their psychological well-being.</p><p><strong>Objectives.: </strong>To determine the prevalence of obsessive-compulsive symptoms among medical students in Peru during the COVID-19 pandemic and its associated factors.</p><p><strong>Materials and methods.: </strong>Cross-sectional study in 270 medical students from a Peruvian public university. Participants were recruited through non-probability sampling. Obsessive-compulsive symptoms were assessed with the Yale-Brown Obsessive Compulsive Disorder Scale (Y-BOCS). After the descriptive analysis, Poisson regression with robust variance was used to determine the factors associated with probable obsessive compulsive disorder (probable OCD). The crude (PRc) and adjusted (PRa) prevalence ratios were calculated, along with their respective 95% confidence intervals (95% CI).</p><p><strong>Results.: </strong>The prevalence of obsessive-compulsive symptoms was 13.3% in medical students. During bivariate analysis, students with probable OCD were younger (p=0.044) and had a lower level of knowledge about COVID-19 (p=0.045). The crude model showed a lower prevalence of probable OCD among those with an adequate level of knowledge compared to those with an inadequate level (PR: 0.52, 95% CI: 0.28 to 0.98). However, after adjusting for other variables, none of the described variables were statistically significant.</p><p><strong>Conclusions.: </strong>One in ten medical students presented clinically significant obsessive-compulsive symptoms. Implementing future interventions is crucial to preserve the mental well-being of this vulnerable population.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"259-265"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of COVID-19-associated multisystemic inflammatory syndrome in children treated in a Peruvian hospital, 2020-2022.","authors":"Noé Atamari-Anahui, Cynthia Huby-Muñoz, Claudia Peña-Coello, Deli Guillen-Buleje, Luis Gomez-Martinez, Héctor Nuñez-Paucar, Mariela Zamudio-Aquise, Raúl Bernal-Mancilla, Liz De Coll-Vela, Carlos Orellana-Siuce, Jorge Candela-Herrera","doi":"10.17843/rpmesp.2024.413.13736","DOIUrl":"10.17843/rpmesp.2024.413.13736","url":null,"abstract":"<p><strong>Background: </strong>Motivation for the study. There are few studies describing the variation of COVID-19-associated multisystem inflammatory syndrome (MIS-C) in Peru across pandemic waves.</p><p><strong>Background: </strong>Main findings. Cases of MIS-C decreased during the first three years of the pandemic, with higher frequency in the second wave with clinical features similar to Kawasaki disease.</p><p><strong>Background: </strong>Implications. MIS-C is a post-infectious complication of SARS-CoV-2. Its diagnostic suspicion is important weeks after peak infections, especially in children who have not yet received COVID-19 vaccines.</p><p><strong>Background: </strong>This study aimed to describe the characteristics of multisystemic inflammatory syndrome associated with COVID-19 (MIS-C) in the first three years of the pandemic in children in a pediatric hospital in Peru. We conducted an observational, descriptive study with data from 73 patients and described the clinical and laboratory characteristics, treatment and complications according to the wave of the pandemic and whether they had shock. The median age was 6 years, gastrointestinal and mucocutaneous manifestations were frequent in the three waves. Kawasaki disease-like phenotype was present in 34 (46.6%) patients and 21 (28.8%) patients developed shock. The most commonly used treatment was immunoglobulin (95.9%), followed by acetylsalicylic acid (94.5%) and corticosteroid (86.3%). Five (7%) patients had coronary aneurysm and 17 (23.3%) were admitted to the intensive care unit (ICU). Patients with shock had greater laboratorial alteration and need for mechanical ventilation. In conclusion, MIS-C has decreased in the first three years of the pandemic, possibly due to COVID-19 vaccination in children.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"301-308"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 and protection measures adopted in rural amazon communities during the first months of the pandemic.","authors":"Christian Abizaid, Yoshito Takasaki, Oliver T Coomes","doi":"10.17843/rpmesp.2024.413.13017","DOIUrl":"10.17843/rpmesp.2024.413.13017","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Motivation for the study. To document the evolution of COVID-19 in rural Amazonian populations, which are still little known.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Main findings. COVID-19 spread rapidly through rural communities, initially spreading to mestizo hamlets and later affecting indigenous communities. Rural mortality varied by region and ethnicity. Social distancing was difficult, and travel to receive government vouchers contributed to contagion.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Implications. Identifying the factors that contributed to contagion and the barriers to the adoption of protective measures in rural Amazonian populations will help to face future pandemics.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objectives.: &lt;/strong&gt;To analyze the evolution of COVID-19 in rural populations of Loreto and Ucayali in the early stage of the pandemic.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods.: &lt;/strong&gt;A community-level longitudinal observational study was conducted and based on two rounds of telephone surveys with local authorities of more than 400 indigenous and non-indigenous rural communities in Loreto and Ucayali, in July and August 2020. We collected information on cases and deaths by COVID-19 in their communities, protective measures adopted and if state assistance was received in the early stage of the pandemic. Descriptive statistics allowed us to evaluate the evolution of the pandemic after the initial outbreak and compare the trends of the two regions, as well as between indigenous and non-indigenous populations.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results.: &lt;/strong&gt;In July 2020, COVID-19 had reached 91.5% of the communities, although deaths from COVID-19 were reported in 13.0% of the communities, with rural mortality being higher in Ucayali (0.111%) than in Loreto (0.047%) and in non-indigenous communities. By August, prevalence decreased from 44.0% to 32.0% of communities, but became more frequent in indigenous communities, and those in Ucayali. Traveling to the city to receive state bonuses and difficulties maintaining social distancing contributed to the spread.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions.: &lt;/strong&gt;Our findings show the evolution of COVID-19 in rural communities and point to important areas of attention in future public policies, for the adoption of protective measures and reconsidering strategies for the distribution of assistance in the face of future pandemics.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Motivation for the study. To document the evolution of COVID-19 in rural Amazonian populations, which are still little known.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Main findings. COVID-19 spread rapidly through rural communities, initially spreading to mestizo hamlets and later affecting indigenous communities. Rural mortality varied by region and ethnicity. Social distancing was difficult, and travel to receive government vouchers contributed to contagion.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Implications. Identifying the factors that contributed to contagion an","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"239-246"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific research and publications in health: aimed at the value of knowledge and solution-based approaches solucionática.","authors":"César Cabezas","doi":"10.17843/rpmesp.2024.413.14277","DOIUrl":"10.17843/rpmesp.2024.413.14277","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"236-238"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening, prevention and early diagnosis of preeclampsia: need for an updated protocol in Peru.","authors":"Rommy H Novoa, Carlos Pérez-Aliaga, Jose E Castañeda-Apolinario, Alexandra I Ramírez-Moreno, Luis Meza-Santibañez","doi":"10.17843/rpmesp.2024.413.13793","DOIUrl":"10.17843/rpmesp.2024.413.13793","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"321-323"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How much has the prevalence of anemia in Peruvian women changed with the WHO 2024 criteria? analysis of ENDES 2023.","authors":"Akram Hernández-Vásquez, Jamee Guerra Valencia, Rodrigo Vargas-Fernández","doi":"10.17843/rpmesp.2024.413.13993","DOIUrl":"10.17843/rpmesp.2024.413.13993","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"324-326"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meningitis and neurosensory hypoacousia due to Rickettsia sp. in Peru: case report.","authors":"Mario J Agramonte, Stalin Vilcarromero, Zoila Núñez-Melgar","doi":"10.17843/rpmesp.2024.413.13393","DOIUrl":"https://doi.org/10.17843/rpmesp.2024.413.13393","url":null,"abstract":"<p><strong>Background: </strong>We present the case of a young female health worker, resident in a high Andean region of Peru, with recent exposure to farm animals and arthropods, who developed acute febrile undifferentiated syndrome, severe thrombocytopenia and pulmonary and abdominal extravasation. Subsequently, the patient developed meningitis and early onset bilateral neurosensorial hypoacusis and showed reactive serology to acute infection by Rickettsia sp. Epidemiological and clinical considerations in the differential diagnosis for early management are discussed.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"41 3","pages":"316-320"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142516749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}