Revista Peruana de Medicina de Experimental y Salud Publica最新文献_第10页

Paper mills as a reflection of the decline of scientific practices in our country. 造纸厂反映了我国科学实践的衰落。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 DOI: 10.17843/rpmesp.2023.404.13447

Lely Solari, César Cabezas

引用次数: 0

Pleural empyema by Parvimonas micra in an immunocompetent patient: a case report. 一名免疫功能正常的患者因小肠伞菌引起的胸腔积液：病例报告。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 Epub Date: 2023-06-23 DOI: 10.17843/rpmesp.2023.401.11956

Stalin Vilcarromero, Max Small, Alexis Lizarzaburu, Abel Rivadeneyra-Rodriguez

{"title":"Pleural empyema by Parvimonas micra in an immunocompetent patient: a case report.","authors":"Stalin Vilcarromero, Max Small, Alexis Lizarzaburu, Abel Rivadeneyra-Rodriguez","doi":"10.17843/rpmesp.2023.401.11956","DOIUrl":"10.17843/rpmesp.2023.401.11956","url":null,"abstract":"We present the case of a young immunocompetent patient, with a history of pulmonary tuberculosis, who attended the hospital with a subacute clinical picture of persistent fever, weight loss, dyspnea and abolition of vesicular murmur. Chest CT scan showed an extensive empyema in the left hemithorax. Samples were taken for detection of common germs. Then, a chest drainage tube was placed and antibiotic therapy started. The MALDI-TOF MS test identified Parvimonas micra, an anaerobic bacterium, commensal to the oral flora, associated with severe periodontitis, but rarely reported in cases of pleural empyema, especially in immunocompetent patients. Gingivitis and pericoronaritis of the third molar were diagnosed during oral evaluation. The patient progressed favorably. Parvimonas micra should be considered as a possible etiological agent in cases of subacute or chronic pleural empyema, in addition to mycobacteria. Tests such as MALDI-TOF MS or 16S rRNA sequencing, chest tube placement, empirical antibiotic coverage and an adequate oral evaluation should be considered in these cases.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 1","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic rhinitis associated with the degree of pulmonary involvement due to COVID-19 in patients from a peruvian general hospital. 秘鲁一家综合医院患者的过敏性鼻炎与 COVID-19 导致的肺部受累程度相关。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 Epub Date: 2023-06-23 DOI: 10.17843/rpmesp.2023.401.12491

Bianca García-Gallo, Giancarlo Gonzales-Caldas, Diego Urrunaga-Pastor, Percy Herrera-Añazco

{"title":"Allergic rhinitis associated with the degree of pulmonary involvement due to COVID-19 in patients from a peruvian general hospital.","authors":"Bianca García-Gallo, Giancarlo Gonzales-Caldas, Diego Urrunaga-Pastor, Percy Herrera-Añazco","doi":"10.17843/rpmesp.2023.401.12491","DOIUrl":"10.17843/rpmesp.2023.401.12491","url":null,"abstract":"Objectives.: To evaluate the association between allergic rhinitis and the degree of pulmonary involvement in patients with COVID-19 and to determine the frequencies of the main variables.Materials and methods.: An observational, cross-sectional and analytical study was carried out by reviewing the medical records of patients diagnosed with COVID-19 from the Cayetano Heredia National Hospital between 2020 and 2021. We obtained information regarding the history of allergic rhinitis; pulmonary involvement was assessed by non-contrast tomography results using the chest computed tomography (CT) score. Data regarding sociodemographic and clinical variables was also obtained. Both crude (PR) and adjusted (aPR) prevalence ratios with their respective 95% confidence intervals (CI) were estimated. We also used a generalized linear Poisson family model with log link function and robust variances.Results.: We evaluated 434 patients, who were mostly male, older than 60 years and had no relevant medical history. Of these, 56.2% had a history of allergic rhinitis and 43.1% had moderate to severe pulmonary involvement. The adjusted regression model showed that the history of allergic rhinitis reduced the severity of COVID-19 according to the pulmonary involvement assessed by the CT score (aPR: 0.70; 95%CI: 0.56-0.88; p=0.002).Conclusions.: The history of allergic rhinitis resulted in a 30.0% decrease in COVID-19 severity according to the CT score in hospitalized patients.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 1","pages":"51-58"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9748648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Climate change and health: atipasunchu allín kausayta? Can we have health and well-being? 气候变化与健康：atipasunchu allín kausayta？我们能拥有健康和幸福吗？

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 Epub Date: 2023-06-23 DOI: 10.17843/rpmesp.2023.401.12333

César Cabezas

引用次数: 0

Characteristics and factors associated with mortality in tracheostomized patients with COVID-19: a retrospective cohort study in a hospital in Tacna, Peru. COVID-19气管插管患者的特征以及与死亡率相关的因素：秘鲁塔克纳一家医院的回顾性队列研究。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 DOI: 10.17843/rpmesp.2023.404.12629

Rodrigo Jesús Flores Palacios, Miguel Hueda Zavaleta, Andrés Guillermo Gutiérrez Avila, Juan Carlos Gómez de la Torre, Vicente Aleixandre Benites Zapata

{"title":"Characteristics and factors associated with mortality in tracheostomized patients with COVID-19: a retrospective cohort study in a hospital in Tacna, Peru.","authors":"Rodrigo Jesús Flores Palacios, Miguel Hueda Zavaleta, Andrés Guillermo Gutiérrez Avila, Juan Carlos Gómez de la Torre, Vicente Aleixandre Benites Zapata","doi":"10.17843/rpmesp.2023.404.12629","DOIUrl":"10.17843/rpmesp.2023.404.12629","url":null,"abstract":"Objective: We aimed to describe the main demographic, clinical, laboratory and therapeutic characteristics and to identify whether they are associated with mortality in tracheostomized patients.Material and methods.: Retrospective cohort study in adult patients diagnosed with COVID-19, admitted to ICU (Intensive Care Unit) and requiring tracheostomy. Demographic, clinical, laboratory and treatment data were obtained from the medical records of patients admitted to Hospital III Daniel Alcides Carrión in Tacna. The Cox proportional hazards model was used for survival analysis and hazard ratios (HR) with their 95% confidence intervals (95%CI) were calculated.Results.: We evaluated 73 patients, 72.6% were men, the most common comorbidities were obesity (68.5%), type 2 diabetes mellitus (35.6%), and arterial hypertension (34.2%). Thirty-seven percent of the participants died during their stay at the ICU. The median time from intubation to tracheostomy and the duration of tracheostomy was 17 (RIC: 15-21) and 21 (RIC: 3-39) days, respectively. Multivariate analysis showed that the factors associated with mortality were procalcitonin > 0.50 ng/dL at the time of tracheostomy (HRa: 2.40 95%CI: 1.03-5.59) and a PaO2/FiO2 ratio less than or equal to 150 mmHg (HRa: 4.44 95%CI: 1.56-12.60).Conclusions.: The factors associated with mortality at the time of tracheostomy were procalcitonin > 0.50 ng/dL and a PaO2/FiO2 ratio less than or equal to 150 mmHg.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 4","pages":"441-450"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11138828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploratory review on the evidence of Andean crops with hypoglycemic effect and their bioactive components. 对安第斯作物具有降血糖作用的证据及其生物活性成分的探索性综述。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 DOI: 10.17843/rpmesp.2023.404.12672

Diego Díaz-Núñez, Boris Rivera-Torres

{"title":"Exploratory review on the evidence of Andean crops with hypoglycemic effect and their bioactive components.","authors":"Diego Díaz-Núñez, Boris Rivera-Torres","doi":"10.17843/rpmesp.2023.404.12672","DOIUrl":"10.17843/rpmesp.2023.404.12672","url":null,"abstract":"Diabetes is a chronic disease that affects several people around the world. Some domesticated crops in South America have been reported to be a promising source of bioactive compounds with possible hypoglycemic effects. In this review we aimed to explore and synthesize the existing evidence in the scientific literature on the hypoglycemic effect of Andean crops and their bioactive components. We included different types of primary studies from three databases (Scopus, Pubmed and Web of Science) during June 2023, without restrictions, by means of controlled and uncontrolled language, according to the PICO strategy. We found 30 studies conducted between 2005 and 2022 that reported a hypoglycemic effect, through enzymatic inhibition in in vitro studies and significant glucose reduction in preclinical studies and clinical trials. This effect was attributed to different bioactive components that were identified with independent mechanisms related to glucose reduction and enzymatic inhibition. The most commonly used cultures were Smallanthus sonchifolius (9/30), Lupinus mutabilis (5/30) and Solanum tuberosum (4/30). The hypoglycemic effect was assigned to bioactive components such as polyphenols, flavonoids, phenolic acid subclasses, fructans, alkaloids, hydrolysates, anthocyanins and dietary fiber. Despite encouraging results from different types of studies, further research on their mechanisms of action, their efficacy compared to conventional treatments and their long-term safety is required for these to be considered safe and effective treatments.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 4","pages":"474-484"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11138825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening for chagas disease in the Peruvian amazon. 在秘鲁亚马逊地区筛查南美锥虫病。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 DOI: 10.17843/rpmesp.2023.404.13009

Silvia Otero-Rodríguez, Juan Carlos Celis-Salinas, Cesar Ramal-Asayag, Martín Casapía-Morales, José-Manuel Ramos-Rincón

引用次数: 0

Use of liposomal amphotericin B in disseminated cutaneous leishmaniasis caused by Leishmania braziliensis in a pediatric patient with Down syndrome. 使用脂质体两性霉素 B 治疗一名患有唐氏综合征的儿童患者由巴西利什曼病引起的播散性皮肤利什曼病。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 Epub Date: 2023-06-23 DOI: 10.17843/rpmesp.2023.401.11481

Aidé Sandoval-Juárez, Nyshon Rojas-Palomino, Lenka Kolevic Roca, Graciela Pilares-Barco, Jorge Cuadros-Castro, Roger Araujo-Castillo

{"title":"Use of liposomal amphotericin B in disseminated cutaneous leishmaniasis caused by Leishmania braziliensis in a pediatric patient with Down syndrome.","authors":"Aidé Sandoval-Juárez, Nyshon Rojas-Palomino, Lenka Kolevic Roca, Graciela Pilares-Barco, Jorge Cuadros-Castro, Roger Araujo-Castillo","doi":"10.17843/rpmesp.2023.401.11481","DOIUrl":"10.17843/rpmesp.2023.401.11481","url":null,"abstract":"We present a case of disseminated cutaneous leishmaniasis with extensive manifestation in a pediatric patient with Down syndrome. The case was confirmed by parasitological and immunological tests. The species was identified as Leishmania (Viannia) braziliensis by polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP). The immune deficit that occurs as part of Down syndrome may have been the reason for the aggressive and prolonged clinical manifestations as well as the poor response to stibogluconate and deoxycholate amphotericin. The patient was treated with liposomal amphotericin B and at the end of therapy, showed clinical improvement of the lesions. This report highlights the challenges of the diagnosis and treatment of cutaneous leishmaniasis in immunosuppressed pediatric patients, especially under difficult social, economic and geographic conditions. Leishmaniasis should be considered as a differential diagnosis when treating atypical chronic dermatologic ulcers; the use of liposomal amphotericin in immunocompromised patients should also be considered in these cases.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 1","pages":"94-98"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric oxygen therapy as an adjunctive treatment for COVID-19-associated mucormycosis: a report of two cases. 高压氧疗法作为 COVID-19 相关黏液瘤病的辅助治疗方法：两例病例报告。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 Epub Date: 2023-06-23 DOI: 10.17843/rpmesp.2023.401.11980

Víctor Valencia-Caballero, José Cachay-Diaz, José Huamán-Muñante, Lourdes Romaní-Montoro, Norka Vásquez-Zevallos, César Carozzi-Calvo, Cesar Chian-García, Hugo Hernández-Chávez, Cristhian Agustín-Paredes, Esteban Vergara-de la Rosa

{"title":"Hyperbaric oxygen therapy as an adjunctive treatment for COVID-19-associated mucormycosis: a report of two cases.","authors":"Víctor Valencia-Caballero, José Cachay-Diaz, José Huamán-Muñante, Lourdes Romaní-Montoro, Norka Vásquez-Zevallos, César Carozzi-Calvo, Cesar Chian-García, Hugo Hernández-Chávez, Cristhian Agustín-Paredes, Esteban Vergara-de la Rosa","doi":"10.17843/rpmesp.2023.401.11980","DOIUrl":"10.17843/rpmesp.2023.401.11980","url":null,"abstract":"Objective.: We present the first two cases reported in Peru of the use of adjuvant hyperbaric oxygen therapy (HBOT) in patients with COVID-19-associated mucormycosis (CAM). The first case is a 41-year-old woman, with pain in the left side of the face and palatine region with purulent rhinorrhea for a month. Only an oroantral fistula was found during physical examination. The second case is a 35-year-old male, with decreased left visual acuity and palatal pain with a fistula, draining purulent secretion for four months. Both patients have history of diabetes, had moderate COVID-19 four months prior to admission, and received corticosteroid therapy for this diagnosis. Tomographic evaluation of both patients showed involvement of the maxillary sinus and surrounding bone tissue; both received diagnostic and therapeutic nasal endoscopy for debridement. Histological analysis showed that the samples were compatible with mucormycosis. The patients underwent debridement and were treated with amphotericin B deoxycholate; however, they presented torpid evolution. Then, HBOT was added and the patients showed an evident improvement after four weeks of treatment with subsequent controls without the presence of mucormycosis. We highlight the favorable evolution of these patients while receiving HBOT as treatment for a disease with high morbimortality, which emerged during the pandemic.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 1","pages":"105-110"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9748149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between the degree of severity of COVID-19 infection during pregnancy and preterm premature rupture of membranes in a level III hospital in Peru. 秘鲁一家三级医院中孕期 COVID-19 感染严重程度与胎膜早破之间的关系。

Revista Peruana de Medicina de Experimental y Salud Publica Pub Date : 2023-01-01 DOI: 10.17843/rpmesp.2023.404.12957

Aitana Palma, Adrian Niño-Huertas, Guido Bendezu-Quispe, Percy Herrera-Añazco

{"title":"Association between the degree of severity of COVID-19 infection during pregnancy and preterm premature rupture of membranes in a level III hospital in Peru.","authors":"Aitana Palma, Adrian Niño-Huertas, Guido Bendezu-Quispe, Percy Herrera-Añazco","doi":"10.17843/rpmesp.2023.404.12957","DOIUrl":"10.17843/rpmesp.2023.404.12957","url":null,"abstract":"Objectives.: To determine the association between the degree of severity of COVID-19 infection during pregnancy and preterm premature rupture of membranes (PPROM) in a level III hospital in Peru.Materials and methods.: Cross-sectional, analytical and observational study in women older than 18 years diagnosed with COVID-19 infection during pregnancy, between the years 2020 and 2022. Clinical and obstetric variables were collected. The chi-square and Fisher's exact tests were used for the descriptive analysis. For the multivariate analysis, we calculated the prevalence ratio by using Poisson regression in crude and adjusted models. All statistical tests were performed considering a value of p<0.05 as significant and with a confidence level of 95%.Results.: We analyzed data from 163 pregnant women with COVID-19, of which 9.2% had PPROM; all were symptomatic cases. Mild COVID-19 cases were 1.10 times more likely to have PPROM (RPa=1.10; 95%CI: 1.02-1.18) and moderate/severe cases were 1.64 times more likely (RPa=1.64; 95%CI: 1.43-1.87), compared to asymptomatic cases.Conclusions.: We identified that a higher degree of severity of COVID-19 infection during pregnancy was associated with a higher probability of having PPROM.","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"40 4","pages":"432-440"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11138821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0