Revista Peruana de Medicina de Experimental y Salud Publica最新文献

{"title":"Acute viral respiratory infections in children before and during the COVID-19 pandemic in a Peruvian reference hospital.","authors":"Jhonatan R Mejia, Daniel Fernandez-Guzman, Medalit Luna-Vilchez, Alvaro Taype-Rondan","doi":"10.17843/rpmesp.2026.433.15564","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.15564","url":null,"abstract":"<p><p>Our objective was to evaluate the frequency and characteristics of acute respiratory infections (ARI) with confirmed viral etiology in children treated at a Peruvian referral hospital before and during the COVID-19 pandemic between 2019 and 2022. We conducted a descriptive study based on the detection records of adenovirus, influenza A and B (IA and IB), parainfluenza 1-3 (PIV), metapneumovirus (hMPV), and respiratory syncytial virus (RSV). Of 1740 episodes (1220 patients), 14.4% tested positive: 196 (78.0%) RSV, 23 (9.2%) IA, 14 (5.6%) PIV-3, and 13 (5.2%) hMPV. In children under five years of age, RSV predominated, while in children over five years of age, it was IA. The frequency of ARI was lower with increasing age, during the pandemic (2020-2021), and the spring and summer seasons. The higher frequency of respiratory viruses in 2022 highlights the need to maintain and strengthen surveillance and preparedness against these outbreaks.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"349-355"},"PeriodicalIF":1.1,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report of Aedes albopictus (diptera: culicidae) for Peru.","authors":"Carlos Gustavo Tong Rios, Johnny Darío Ramírez Fernández, Clara Rosa Del Águila Morante, Freddy Gutiérrez Rodríguez, José Luis Barboza Chichipe, Becker Amilton Reyna Aspajo, Gladys Giannina Vásquez Del Águila, Edwin Requena-Zuñiga","doi":"10.17843/rpmesp.2026.433.16375","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.16375","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"415-418"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial resistance and vaccine-preventable infections: concurrent health security challenges after the double earthquake in Venezuela.","authors":"María Araque","doi":"10.17843/rpmesp.2026.433.17138","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.17138","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"298-300"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organizing ourselves for a conscious use of artificial intelligence in scientific publications: human responsibility as guiding principle.","authors":"Lely Solari","doi":"10.17843/rpmesp.2026.433.17075","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.17075","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"296-297"},"PeriodicalIF":1.1,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma fractionation in Latin America: a path towards sovereignty and sustainability in the supply of plasma-derived medicines.","authors":"Andrea C Zucchi, Silvina Del V Druetta","doi":"10.17843/rpmesp.2026.433.15418","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.15418","url":null,"abstract":"<p><p>The supply of plasma-derived medicinal products (PDMPs) is a critical global challenge, especially in low and middle-income countries. In Latin America, thousands of liters of plasma are discarded annually. This work proposes alternative and concrete strategies to initiate plasma fractionation in Latin America. The Hemoderivatives Laboratory of the National University of Córdoba (LHUNC) has implemented a successful regional cooperation model with Uruguay, Chile, and Paraguay. This exchange system allows countries to deliver plasma and receive PDMPs without the need to transfer foreign currency, overcoming barriers such as the lack of national blood plans or low initial collection volumes. In conclusion, the LHUNC experience demonstrates that plasma utilization through proximity alliances is an ethical and financially viable alternative to achieve health sovereignty and reduce regional vulnerability to global market volatility.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"390-396"},"PeriodicalIF":1.1,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hampi Tariki Kit: thin-layer chromatography for semiquantitative screening of solid oral medicines in Peru.","authors":"Gladys M Mónico-Rosales, Fredy R Mostacero-Rodríguez, B Rosa Quispe-Paitán, E Javier Rodríguez-Calzado, Juan J Ortiz-Bernaola, Alejandro Nuñez-Galindo","doi":"10.17843/rpmesp.2026.433.15446","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.15446","url":null,"abstract":"<p><strong>Objectives: </strong>To develop and validate rapid thin-layer chromatography (TLC) methods integrated into the Hampi Tariki kit for the semiquantitative screening of active pharmaceutical ingredients (APIs) in oral solid medications marketed in Peru.</p><p><strong>Materials and methods: </strong>Eight TLC methods were developed and validated for tablets and capsules containing acyclovir, dicloxacillin, dimenhydrinate, ibuprofen, diclofenac sodium, paracetamol, norfloxacin, phenazopyridine hydrochloride, chlorphenamine maleate, and phenylephrine hydrochloride. Fifty-seven commercial samples available in the national market, from different manufacturing laboratories, including branded and generic products previously verified as compliant by official methods at the Centro Nacional de Control de Calidad (CNCC) of the Instituto Nacional de Salud (INS), were evaluated. Silica gel 60 F254 plates, reference standards, and analytical grade solvents were used. Validation was performed according to ICH Q2(R1) guideline, evaluating selectivity, linearity, precision, accuracy, visual detection limit, and robustness.</p><p><strong>Results: </strong>The methods allowed for visual and densitometric differentiation of levels equivalent to 80%, 100%, and 120% of the declared content. Retention factor (Rf ) values were between 0.20 and 0.85, and multicomponent formulations presented chromatographic resolution ≥1.0. Correlation coefficients were greater than 0.99 for system and method linearity; repeatability showed coefficients of variation less than 3.0%, intermediate precision less than 5.0%, and bias against high-performance liquid chromatography (HPLC) remained within the ±3.00% range. Deliberate variations evaluated in robustness did not produce significant changes in Rf values.</p><p><strong>Conclusions: </strong>The developed methods demonstrated adequate analytical performance as rapid semiquantitative screening tests. Integrated into the Hampi Tariki kit, they constitute a proposal with potential to support the preliminary identification of suspicious samples and prioritize their confirmation by HPLC or other official methods.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"311-320"},"PeriodicalIF":1.1,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elimination and reemergence of measles in Mexico: historical and structural review of the 2025-2026 outbreak.","authors":"Laura Mojica-López, Oswaldo Huchim-Lara, Orlando Paredes-Ceballos","doi":"10.17843/rpmesp.2026.433.16250","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.16250","url":null,"abstract":"<p><p>A documentary analysis of historical, normative, epidemiological, and scientific sources of the structural conditions linked to measles in Mexico was performed to describe the disease's trajectory, examine vaccination coverage gaps, and understand the factors that favored its reemergence after regional elimination. Following the interruption of endemic transmission in 1995 and regional elimination in 2016, the disease reemerged in 2025-2026 in a context of accumulation of susceptible population, incomplete vaccination schedules, and territorial inequalities in access to health services. The outbreak concentrated in territories with suboptimal coverages and higher social vulnerability, which evidenced that the sustainability of elimination does not depend solely on vaccine availability, but also on the health system's capacity to maintain homogeneous coverages, sensitive epidemiological surveillance, and timely responses to case importation.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"384-389"},"PeriodicalIF":1.1,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lyell´s syndrome associated with the use of topical agents: case report.","authors":"Alan P Murillo-Salas, Estephania B Díaz-Panuera, Francheska M Núñez-Gonzales, Aira S Chávez-Panuera, Fabián L Cuba-Pacheco, María F Bernales-Valdivia","doi":"10.17843/rpmesp.2026.433.15468","DOIUrl":"https://doi.org/10.17843/rpmesp.2026.433.15468","url":null,"abstract":"<p><p>Lyell's syndrome (LS) is a severe drug-induced cutaneous adverse reaction, associated with high morbidity and mortality. We present the case of a 41-year-old male who, after the use of topical medications, developed fever, maculopapular lesions, ocular and mucosal involvement, with affectation of more than 30% of the body surface area. Cutaneous biopsy ruled out other pathologies. Management included systemic methylprednisolone, aluminum subacetate, topical mupirocin, ophthalmic prednisolone, and ophthalmic hypromellose, with a favorable outcome and without complications. This case highlights the importance of considering topical medications as possible triggers for LS, as well as the need for early diagnosis and timely management. Early identification and a multidisciplinary therapeutic approach are fundamental to improve clinical outcomes and reduce the morbidity and mortality associated with this entity.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 3","pages":"402-407"},"PeriodicalIF":1.1,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Need and utilization of rehabilitation services in children with cerebral palsy at a referral hospital in Peru: a descriptive study.","authors":"Roger De la Cerna-Luna, Alexander G Acevedo-Cahuana, Brenda Galindo-Yllu, Elvira G Zamora-Huaringa, Mabel Ramirez-Chipana, Pilar Merino-Orbegoso","doi":"10.17843/rpmesp.2026.432.15834","DOIUrl":"10.17843/rpmesp.2026.432.15834","url":null,"abstract":"<p><p>With the objective of describing the characteristics and comparing the need with the previous utilization of rehabilitation services in children with cerebral palsy at a referral hospital in Peru, a descriptive study was conducted through the review of medical records of 86 patients treated during 2024. It was found that 41.8% did not attend any educational institution and 44.2% did not have a disability certificate; among those who had one, the mean time to obtain it was 4.9 years. Less than half had a pelvic radiograph, despite hip dislocation being a frequent comorbidity. Although the majority required rehabilitation therapies, their coverage was limited, especially in occupational therapy and speech/swallowing therapy. Likewise, more than half of those who required botulinum toxin had not received it. These findings demonstrate significant discrepancies between the need and previous utilization of rehabilitation services in this population.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 2","pages":"244-250"},"PeriodicalIF":1.1,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148632847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local scientific relevance in the face of the tyranny of global metrics: the future of the diamond model and health evidence needs in the region.","authors":"Mauricio Palacios Gómez","doi":"10.17843/rpmesp.2026.432.16722","DOIUrl":"10.17843/rpmesp.2026.432.16722","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 2","pages":"158-159"},"PeriodicalIF":1.1,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148632880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}