Manuel Sanchez-Landers, Arnold Frank Rodriguez-Benites
{"title":"与既往登革热相关的格林-巴利综合征:病例报告。","authors":"Manuel Sanchez-Landers, Arnold Frank Rodriguez-Benites","doi":"10.17843/rpmesp.2025.421.13893","DOIUrl":null,"url":null,"abstract":"<p><p>Guillain-Barré syndrome is a potentially severe autoimmune inflammatory polyneuropathy, which is usually associated with previous infections. Dengue is the most common arbovirus infection worldwide, being endemic in tropical and subtropical areas such as Peru. Scientific literature shows some reports of dengue with neurological complications, but its pathophysiology is not well understood. We present the case of a woman from an area endemic for dengue with Guillain-Barré syndrome with a disability scale of 4/6 on the Hughes scale, confirmed by albumin-cytological dissociation, and previous infection with dengue virus confirmed with a positive serum ELISA IgM test. The patient's progress was favorable after receiving intravenous immunoglobulin. It is important to consider this viral infection as a probable risk factor for developing Guillain-Barré syndrome.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"42 1","pages":"88-91"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176019/pdf/","citationCount":"0","resultStr":"{\"title\":\"Guillain-Barre syndrome associated with previous dengue fever: case report.\",\"authors\":\"Manuel Sanchez-Landers, Arnold Frank Rodriguez-Benites\",\"doi\":\"10.17843/rpmesp.2025.421.13893\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Guillain-Barré syndrome is a potentially severe autoimmune inflammatory polyneuropathy, which is usually associated with previous infections. Dengue is the most common arbovirus infection worldwide, being endemic in tropical and subtropical areas such as Peru. Scientific literature shows some reports of dengue with neurological complications, but its pathophysiology is not well understood. We present the case of a woman from an area endemic for dengue with Guillain-Barré syndrome with a disability scale of 4/6 on the Hughes scale, confirmed by albumin-cytological dissociation, and previous infection with dengue virus confirmed with a positive serum ELISA IgM test. The patient's progress was favorable after receiving intravenous immunoglobulin. It is important to consider this viral infection as a probable risk factor for developing Guillain-Barré syndrome.</p>\",\"PeriodicalId\":53651,\"journal\":{\"name\":\"Revista Peruana de Medicina de Experimental y Salud Publica\",\"volume\":\"42 1\",\"pages\":\"88-91\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-06-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176019/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Peruana de Medicina de Experimental y Salud Publica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17843/rpmesp.2025.421.13893\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Peruana de Medicina de Experimental y Salud Publica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17843/rpmesp.2025.421.13893","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Guillain-Barre syndrome associated with previous dengue fever: case report.
Guillain-Barré syndrome is a potentially severe autoimmune inflammatory polyneuropathy, which is usually associated with previous infections. Dengue is the most common arbovirus infection worldwide, being endemic in tropical and subtropical areas such as Peru. Scientific literature shows some reports of dengue with neurological complications, but its pathophysiology is not well understood. We present the case of a woman from an area endemic for dengue with Guillain-Barré syndrome with a disability scale of 4/6 on the Hughes scale, confirmed by albumin-cytological dissociation, and previous infection with dengue virus confirmed with a positive serum ELISA IgM test. The patient's progress was favorable after receiving intravenous immunoglobulin. It is important to consider this viral infection as a probable risk factor for developing Guillain-Barré syndrome.
期刊介绍:
La Revista Peruana de Medicina Experimental y Salud Pública (RPMESP) es el órgano oficial de difusión científica del Instituto Nacional de Salud (INS) del Perú. Es una publicación arbitrada por pares, de periodicidad trimestral, de ámbito y difusión mundial, indizada en MEDLINE/Index Medicos, SCOPUS, EMBASE, SciELO Salud Pública y otras bases de datos internacionales. La RPMESP es distribuida en su versión impresa y electrónica, con acceso gratuito a texto completo. La RPMESP publica artículos referidos a temas del ámbito biomédico y de salud pública, resaltando aportes prácticos, que contribuyan a mejorar la situación de salud del país y de la región. Propicia el intercambio de la experiencia científica en salud entre instituciones y personas dedicadas a la investigación dentro y fuera del Perú a fin de promover el avance y la aplicación de la investigación en salud.