IJU Case Reports最新文献_第7页

A Case of Small Cell Carcinoma of Bladder With Significant Tumor Reduction Following Combination Chemotherapy and Radiation Therapy 膀胱小细胞癌经放化疗后肿瘤明显缩小1例

IJU Case Reports Pub Date : 2025-04-14 DOI: 10.1002/iju5.70031

Rintaro Yoshitake, Syunsuke Taguchi, Yoshimasa Harada

{"title":"A Case of Small Cell Carcinoma of Bladder With Significant Tumor Reduction Following Combination Chemotherapy and Radiation Therapy","authors":"Rintaro Yoshitake, Syunsuke Taguchi, Yoshimasa Harada","doi":"10.1002/iju5.70031","DOIUrl":"https://doi.org/10.1002/iju5.70031","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Small cell carcinoma of the bladder (SCCB) is a rare and aggressive disease with no established standard treatment. We report a case of SCCB that initially progressed with chemotherapy but responded well to a combination of chemotherapy and radiotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 62-year-old man presented with painless gross hematuria. Transurethral resection of the bladder tumor (TURBT) confirmed SCCB. Gemcitabine-carboplatin (GEM-CBDCA) and pembrolizumab were ineffective, leading to rapid tumor progression. The patient developed bladder tamponade and obstructive renal failure. Emergency radiotherapy (30 Gy) controlled bleeding, and etoposide-carboplatin chemotherapy resulted in significant tumor shrinkage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlights the potential effectiveness of etoposide-carboplatin and radiotherapy in SCCB, especially in cases resistant to other treatments. Further studies are needed to establish optimal treatment strategies for SCCB.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"289-292"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robot-Assisted Simple Prostatectomy for Two Cases of Benign Prostatic Hyperplasia: The First Report in Japan 机器人辅助单纯前列腺切除术治疗2例良性前列腺增生：日本首例报道

IJU Case Reports Pub Date : 2025-04-14 DOI: 10.1002/iju5.70006

Hiroyuki Kitano, Hayato Yoshioka, Yuto Ono, Rei Ueno, Yoshinori Nakano, Tomoya Hatayama, Kazuma Yukihiro, Kyosuke Iwane, Yuki Kohada, Miki Naito, Kohei Kobatake, Yohei Sekino, Nobuyuki Hinata

{"title":"Robot-Assisted Simple Prostatectomy for Two Cases of Benign Prostatic Hyperplasia: The First Report in Japan","authors":"Hiroyuki Kitano, Hayato Yoshioka, Yuto Ono, Rei Ueno, Yoshinori Nakano, Tomoya Hatayama, Kazuma Yukihiro, Kyosuke Iwane, Yuki Kohada, Miki Naito, Kohei Kobatake, Yohei Sekino, Nobuyuki Hinata","doi":"10.1002/iju5.70006","DOIUrl":"https://doi.org/10.1002/iju5.70006","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Robot-assisted simple prostatectomy is associated with better perioperative outcomes than those of open simple prostatectomy. We report the outcomes of two cases treated with robot-assisted simple prostatectomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>The first patient was an 81-year-old man with a prostate volume of 139 mL. The second patient was a 77-year-old man with a prostate volume of 98 mL. Robot-assisted simple prostatectomy was performed using Da Vinci Xi. The operative times and enucleated weights for the first and second patients were 210 min and 82 g, and 191 min and 53 g, respectively. Postoperative uroflowmetry of the first and second patients revealed maximum flow rates and postvoid residual volumes of 32.5 mL/s and 15 mL at 6 months postoperatively, and 22.1 mL/s and 6 mL at 1 month postoperatively, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Robot-assisted simple prostatectomy is useful for large prostates.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"206-209"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcoid-Like Reaction (SLR) Associated With Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma 转移性肾细胞癌中与免疫检查点抑制剂相关的肉瘤样反应(SLR

IJU Case Reports Pub Date : 2025-04-14 DOI: 10.1002/iju5.70027

Kanta Fukushima, Sota Mizukoshi, Tomohiro Ino, Takuya Ishida, Yumika Ito, Akira Okimura, Munehide Nakatsugawa, Takeshi Hashimoto

{"title":"Sarcoid-Like Reaction (SLR) Associated With Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma","authors":"Kanta Fukushima, Sota Mizukoshi, Tomohiro Ino, Takuya Ishida, Yumika Ito, Akira Okimura, Munehide Nakatsugawa, Takeshi Hashimoto","doi":"10.1002/iju5.70027","DOIUrl":"https://doi.org/10.1002/iju5.70027","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Immune checkpoint inhibitors (ICIs) are useful in the treatment of metastatic renal cell carcinoma. ICIs have been associated with a variety of immune-related adverse events (irAEs), one of which is a sarcoid-like reaction (SLR). SLR is often difficult to distinguish from cancer progression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>The patient is a 71-year-old woman. She underwent laparoscopic nephrectomy after 4 courses of ipilimumab + nivolumab therapy for clear cell renal cell carcinoma with femoral bone metastasis. In the pathological examination, in addition to tumor-infiltrating lymphocytes, numerous non-caseating epithelioid cell granulomas were found in the tumor. The occurrence of non-caseating epithelioid cell granuloma in a patient who did not meet the diagnostic criteria for systemic sarcoidosis was considered SLR due to ICI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We report the first case of a patient who underwent surgery for metastatic renal cell carcinoma after treatment with ICI and who was pathologically diagnosed with SLR in the kidney.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"285-288"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ureteroscopic Lithotripsy for A Surgical Clip-Induced Renal Stone Following Laparoscopic Partial Nephrectomy 输尿管镜碎石术治疗腹腔镜部分肾切除术后夹持性肾结石

IJU Case Reports Pub Date : 2025-04-10 DOI: 10.1002/iju5.70024

Takashi Yoshioka, Hakaru Masumoto, Tomohiro Hongo, Yuji Yata, Sumire Santo, Takuya Hagiwara, Junya Hara, Tomoya Yamasaki, Hideo Otsuki, Kei Fujio

{"title":"Ureteroscopic Lithotripsy for A Surgical Clip-Induced Renal Stone Following Laparoscopic Partial Nephrectomy","authors":"Takashi Yoshioka, Hakaru Masumoto, Tomohiro Hongo, Yuji Yata, Sumire Santo, Takuya Hagiwara, Junya Hara, Tomoya Yamasaki, Hideo Otsuki, Kei Fujio","doi":"10.1002/iju5.70024","DOIUrl":"https://doi.org/10.1002/iju5.70024","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Surgical clips used in laparoscopic and robot-assisted surgeries can occasionally migrate into the upper urinary tract, serving as nidi for stone formation. We report a case of a surgical clip-induced renal stone successfully treated with ureteroscopic lithotripsy (URSL) following laparoscopic partial nephrectomy (LPN).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 37-year-old male with a 17-mm renal stone in the right middle calyx underwent URSL. His surgical history included right LPN performed four years prior, with operative records documenting pyelocaliceal system entry and Hem-o-lok clip placement. During the operation, a Hem-o-lok clip was identified within the stone. All fragments along with the surgical clip were completely retrieved using a basket forceps after laser lithotripsy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlights important clinical considerations: the appropriate use of surgical clips during LPN, selection of optimal endourological treatment approaches for stone removal, and the importance of careful follow-up for early detection and intervention of clips and clip-induced stones.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"276-280"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zinner Syndrome Presenting With Chronic Pelvic Pain and Ejaculatory Dysfunction Zinner综合征表现为慢性盆腔疼痛和射精功能障碍

IJU Case Reports Pub Date : 2025-04-10 DOI: 10.1002/iju5.70029

Tejasvi Patil, Amogh Verma, Rajat Sachdeva, Shubham Kumar, Shilpa Gaidhane, Sanjit Sah, Prakasini Satapathy, Rachana Mehta, Benjamin Wafula Simiyu, Vinay Suresh

{"title":"Zinner Syndrome Presenting With Chronic Pelvic Pain and Ejaculatory Dysfunction","authors":"Tejasvi Patil, Amogh Verma, Rajat Sachdeva, Shubham Kumar, Shilpa Gaidhane, Sanjit Sah, Prakasini Satapathy, Rachana Mehta, Benjamin Wafula Simiyu, Vinay Suresh","doi":"10.1002/iju5.70029","DOIUrl":"https://doi.org/10.1002/iju5.70029","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Zinner Syndrome is a rare congenital anomaly involving unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. We report a symptomatic case managed conservatively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 19-year-old male presented with 6 months of intermittent pelvic pain, dysuria, and ejaculatory discomfort. Examination was unremarkable. Ultrasonography showed right renal agenesis and a pelvic cyst. MRI confirmed a 2.8 cm cystic dilatation of the right seminal vesicle with vas deferens dilatation and absent right kidney. No ectopic renal tissue was seen. Semen analysis revealed oligospermia. Given mild symptoms and fertility concerns, he was treated conservatively with NSAIDs and antibiotics, resulting in symptom improvement within 4 weeks. Surveillance was planned.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Zinner Syndrome should be considered in young males with unexplained pelvic or ejaculatory symptoms. MRI is essential for accurate diagnosis. Conservative treatment is suitable for mild cases, reserving surgery for progressive symptoms or fertility issues.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"322-325"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Waldenström Macroglobulinemia Diagnosed by Ultrasonography-Guided Biopsy of the Right Perinephric Tumor Waldenström右肾周肿瘤超声引导活检诊断巨球蛋白血症

IJU Case Reports Pub Date : 2025-04-09 DOI: 10.1002/iju5.70022

Shingo Morinaga, Shigeyuki Aoki, Motoi Tobiume, Genya Nishikawa, Fusako Higuchi, Yuusuke Ikenohata, Manabu Honda, Hiroe Kubo, Tomoko Sawada, Yoshiaki Yamada

{"title":"Waldenström Macroglobulinemia Diagnosed by Ultrasonography-Guided Biopsy of the Right Perinephric Tumor","authors":"Shingo Morinaga, Shigeyuki Aoki, Motoi Tobiume, Genya Nishikawa, Fusako Higuchi, Yuusuke Ikenohata, Manabu Honda, Hiroe Kubo, Tomoko Sawada, Yoshiaki Yamada","doi":"10.1002/iju5.70022","DOIUrl":"https://doi.org/10.1002/iju5.70022","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Waldenström macroglobulinemia is a low-grade B-cell lymphoma characterized by lymphoplasmacytic lymphoma infiltration of the bone marrow and immunoglobulin M (IgM) protein.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>An 80s-year-old male presented to our hospital with chief complaints of weight loss and general fatigue. Computed tomography (CT) showed homogeneous tumor around the kidney with elevated soluble Interleukin-2 receptor, serum IgM, and β2-microglobulin levels. Histopathological analysis by ultrasonography-guided biopsy revealed dense lymphocytic proliferation, plasmacytoid differentiation, and Dutcher bodies, positive for CD20, CD138, and IgM, but negative for CD3 and CD5, consistent with lymphoplasmacytic lymphoma. Bone marrow biopsy revealed infiltration of the lymphoplasmacytic lymphoma. The patient received four courses of bortezomib, cyclophosphamide, and dexamethasone along with dexamethasone, rituximab, and cyclophosphamide therapy. Twelve months after treatment, CT revealed only slightly enlarged abdominal para-aortic lymph nodes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Malignant lymphoma in perinephric lesions is a relatively rare condition; however, a definitive diagnosis can be obtained by ultrasound-guided biopsy, allowing early initiation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"271-275"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Giant Neobladder Stone of 5 Kg 5公斤巨型新膀胱结石一例

IJU Case Reports Pub Date : 2025-04-09 DOI: 10.1002/iju5.70026

Kaede Hiruma, Masayuki Tasaki, Tsutomu Anraku, Masahiro Ikeda, Kazuhide Saito, Yoshifumi Shimada, Yoshihiko Tomita

{"title":"A Case of Giant Neobladder Stone of 5 Kg","authors":"Kaede Hiruma, Masayuki Tasaki, Tsutomu Anraku, Masahiro Ikeda, Kazuhide Saito, Yoshifumi Shimada, Yoshihiko Tomita","doi":"10.1002/iju5.70026","DOIUrl":"https://doi.org/10.1002/iju5.70026","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Radical cystectomy is the standard treatment for muscle-invasive bladder cancer. A neobladder is created as part of urinary diversion; however, the formation of bladder stones is often a late complication-related concern.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 56-year-old man underwent radical cystectomy and neobladder construction for bladder cancer 25 years ago. A huge neobladder stone was diagnosed when the patient developed a strangulated ileus. Open surgery was performed to remove the bladder stone. The stone's size was 21.6 × 15.5 × 18.5 cm and its weight was 5 kg.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>To the authors' knowledge, this is the largest case of bladder calculus reported to date.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"281-284"},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salvage Surgery Following Remarkable Tumor Shrinkage With Enfortumab Vedotin in Advanced Urothelial Carcinoma 在晚期尿路上皮癌中应用维多汀治疗肿瘤显著缩小后的挽救性手术

IJU Case Reports Pub Date : 2025-04-08 DOI: 10.1002/iju5.70019

Keita Minami, Rei Narimatsu, Hajime Sasaki, Tatsu Tanabe, Hiroshi Tanaka

{"title":"Salvage Surgery Following Remarkable Tumor Shrinkage With Enfortumab Vedotin in Advanced Urothelial Carcinoma","authors":"Keita Minami, Rei Narimatsu, Hajime Sasaki, Tatsu Tanabe, Hiroshi Tanaka","doi":"10.1002/iju5.70019","DOIUrl":"https://doi.org/10.1002/iju5.70019","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>We report a case in which enfortumab vedotin (EV) therapy was administered as a third-line treatment for locally advanced bladder cancer (<span>bc</span>), enabling successful radical resection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>This report describes the case of a 69-year-old male patient with locally advanced <span>bc</span> and pelvic lymph node (LN) metastases. After the failure of first-line chemotherapy and second-line immunotherapy, the patient received EV as third-line treatment. EV therapy resulted in significant tumor reduction, enabling successful radical cystectomy and lymph node dissection (LND). The patient remained recurrence-free for 22 months post-surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>EV therapy suggests that it is a promising avenue for further exploration, potentially redefining the therapeutic landscape of historically challenging cases.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"257-260"},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Secondary Extramammary Paget's Disease Surrounding a Cutaneous Ureterostoma After Recurrence of Bladder Urothelial Carcinoma 膀胱尿路上皮癌复发后继发性乳腺外佩吉特病伴皮肤输尿管瘘1例

IJU Case Reports Pub Date : 2025-03-27 DOI: 10.1002/iju5.70021

Masahiro Mizoguchi, Ichiro Chihara, Keisuke Sano, Tomokazu Kimura, Shuya Kandori, Hiromitsu Negoro, Bryan J. Mathis, Hitomi Kawai, Daisuke Matsubara, Hiroyuki Nishiyama

{"title":"A Case of Secondary Extramammary Paget's Disease Surrounding a Cutaneous Ureterostoma After Recurrence of Bladder Urothelial Carcinoma","authors":"Masahiro Mizoguchi, Ichiro Chihara, Keisuke Sano, Tomokazu Kimura, Shuya Kandori, Hiromitsu Negoro, Bryan J. Mathis, Hitomi Kawai, Daisuke Matsubara, Hiroyuki Nishiyama","doi":"10.1002/iju5.70021","DOIUrl":"https://doi.org/10.1002/iju5.70021","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Secondary extramammary Paget's disease features intraepidermal carcinoma caused by tumor invasion and migration into adjacent skin.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 68-year-old man underwent radical cystectomy and bilateral cutaneous ureterostomy for bladder cancer and right ureteral cancer. Postoperative follow-up computed tomography and urine cytology at 3 years suggested right ureteral cancer recurrence. Contemporaneous erythema and bulging of the skin around the right ureterocutaneous fistula were observed, necessitating retroperitoneoscopic nephroureterectomy and peristomal skin resection. Pathology revealed urothelial carcinoma with T2 disease at the lower ureter, plus spreading cytokeratin 7+ and cytokeratin 20+ pagetoid cells clustered within the epidermis indicative of secondary Paget's disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In cases of recurrent upper urothelial carcinoma after urinary diversion, patients may develop secondary extramammary Paget's disease of the skin.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"266-270"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Achieving Urinary Continence Using Gracilis Muscle Flap for Recanalization and Fistula After Bladder Neck Closure 膀胱颈闭合后应用股薄肌瓣再通瘘实现尿失禁一例

IJU Case Reports Pub Date : 2025-03-26 DOI: 10.1002/iju5.70012

Naoki Wada, Haruka Takagi, Taichiro Ishimaru, Daiki Kikuchi, Miyu Ohtani, Hidehiro Kakizaki, Takeshi Yamao, Toshihiko Hayashi

{"title":"A Case of Achieving Urinary Continence Using Gracilis Muscle Flap for Recanalization and Fistula After Bladder Neck Closure","authors":"Naoki Wada, Haruka Takagi, Taichiro Ishimaru, Daiki Kikuchi, Miyu Ohtani, Hidehiro Kakizaki, Takeshi Yamao, Toshihiko Hayashi","doi":"10.1002/iju5.70012","DOIUrl":"https://doi.org/10.1002/iju5.70012","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>We present the case of a patient who achieved urinary continence after undergoing a gracilis muscle flap (GMF) for recanalization and fistula after bladder neck closure (BNC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A male patient with neurogenic lower urinary tract dysfunction complained of difficulty inserting the catheter because of numerous false cavities in the prostatic urethra. We performed BNC to create a continent catheterizable stoma. However, the bladder neck was recanalized in the early postoperative period. Next, we dissected and closed the urethra transperineally. Due to the tiny fistula, the patient's urinary incontinence persisted. Finally, we dissected and closed the urethra again transperineally, and the closed area was covered with a GMF. Since then, the urethra has been completely closed, and urinary continence has been achieved.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The possibility of recanalization after BNC must be kept in mind. Interposition and covering of the GMF are useful techniques for urethral and perineal fistulas.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 3","pages":"227-230"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0