IJU Case Reports最新文献_第6页

Carboplatin Monotherapy Induced Complete Response in Elderly Metastatic Seminoma and CKD: A Case Report 卡铂单药治疗老年转移性精原细胞瘤和CKD的完全缓解：1例报告。

IF 0.5

IJU Case Reports Pub Date : 2026-08-05 DOI: 10.1002/iju5.70241

Gento Omae, Kosuke Kitamura, Satoru Muto

{"title":"Carboplatin Monotherapy Induced Complete Response in Elderly Metastatic Seminoma and CKD: A Case Report","authors":"Gento Omae, Kosuke Kitamura, Satoru Muto","doi":"10.1002/iju5.70241","DOIUrl":"10.1002/iju5.70241","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Cisplatin-based chemotherapy is the standard treatment for metastatic seminoma but may be unsuitable for elderly patients with comorbidities. We report a case of metastatic seminoma with chronic kidney disease (CKD) in an elderly patient successfully treated with carboplatin monotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 70-year-old man presented with a left testicular tumor and para-aortic lymphadenopathy, causing left-sided hydronephrosis. Radical left high orchiectomy confirmed stage IIC pure seminoma pT1N3M0 with a favorable prognosis according to the International Germ Cell Cancer Collaborative Group classification. Because renal impairment and poor performance status precluded cisplatin-based chemotherapy, the patient received four cycles of carboplatin monotherapy (AUC 7). Grade 2–3 pancytopenia occurred but was manageable with pegfilgrastim and dose interval adjustment. Post-treatment PET-CT showed no residual uptake. Consolidation para-aortic radiotherapy was subsequently performed. The patient remains disease-free 1.5 years after treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Carboplatin monotherapy may be a feasible alternative for metastatic seminoma patients who are unsuitable for cisplatin-based chemotherapy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bladder Perforation Following Transurethral Resection of Bladder Tumor With Immediate Intravesical Instillation of Epirubicin 经尿道膀胱肿瘤切除术后膀胱穿孔立即膀胱内滴注表阿霉素

IF 0.5

IJU Case Reports Pub Date : 2026-07-28 DOI: 10.1002/iju5.70235

Junya Abe, Atsuro Sawada, Chie Onizuka, Takahiro Akioka, Naoko Nakai, Shimpei Kojima, Hiroki Sakamoto, Tomoya Horinouchi, Toshiyuki Kamoto

{"title":"Bladder Perforation Following Transurethral Resection of Bladder Tumor With Immediate Intravesical Instillation of Epirubicin","authors":"Junya Abe, Atsuro Sawada, Chie Onizuka, Takahiro Akioka, Naoko Nakai, Shimpei Kojima, Hiroki Sakamoto, Tomoya Horinouchi, Toshiyuki Kamoto","doi":"10.1002/iju5.70235","DOIUrl":"https://doi.org/10.1002/iju5.70235","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Immediate postoperative intravesical chemotherapy following transurethral resection of bladder tumor (TURBT) is the standard procedure aimed at reducing recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>An 84-year-old man was diagnosed with an incidental 13-mm intravesical tumor during screening for biochemical recurrence following radiation therapy for prostate cancer. Accordingly, he underwent TURBT, followed by immediate postoperative intravesical chemotherapy with epirubicin. On postoperative day 2, he developed abdominal pain. Computed tomography demonstrated bladder perforation accompanied by retroperitoneal free air. He was diagnosed with extraperitoneal bladder perforation and thus managed with urethral catheterization; however, conservative treatment failed. Consequently, surgical repair with debridement was performed. Pale whitish granulation tissue was observed within the perivesical fat, suggesting epirubicin extravasation. Subsequently, cystography performed 28 days after bladder repair showed no contrast extravasation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Surgical treatment should be considered as a potential treatment option for patients with suspected chemotherapy extravasation in whom conservative management is unsuccessful.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70235","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant Adrenal Oncocytoma: A Case Report and Literature Review 巨大肾上腺嗜瘤细胞瘤1例报告及文献复习。

IF 0.5

IJU Case Reports Pub Date : 2026-07-27 DOI: 10.1002/iju5.70238

Kohei Yamakawa, Akihiro Ono, Ryo Amakawa, Hirotomo Koda, Ryohei Nishimoto, Yasushi Inoue, Teppei Morikawa, Masashi Kusakabe, Haruki Kume, Masaki Nakamura

{"title":"Giant Adrenal Oncocytoma: A Case Report and Literature Review","authors":"Kohei Yamakawa, Akihiro Ono, Ryo Amakawa, Hirotomo Koda, Ryohei Nishimoto, Yasushi Inoue, Teppei Morikawa, Masashi Kusakabe, Haruki Kume, Masaki Nakamura","doi":"10.1002/iju5.70238","DOIUrl":"10.1002/iju5.70238","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Adrenal oncocytomas are rare, nonfunctioning tumors composed of eosinophilic oncocytic cells whose nonspecific imaging often impedes preoperative diagnosis. We report a case of a large nonfunctioning adrenal oncocytoma with borderline malignant potential, incidentally discovered during cardiac symptom evaluation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 77-year-old man with an incidentally discovered retroperitoneal tumor was referred to Urology for further evaluation. Contrast-enhanced CT revealed a 93-mm lobulated mass with heterogeneous enhancement abutting the left kidney's upper pole. Given the tumor's size, open left nephrectomy and adrenalectomy were performed. Gross and histopathology revealed a yellowish, solid adrenal tumor composed predominantly of oncocytic cells with no invasion of the kidney. Immunohistochemistry revealed a low Ki-67 index (approximately 2%). The tumor was classified as having borderline malignant potential (Lin–Weiss–Bisceglia criteria).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We present a rare case of nonfunctioning adrenal oncocytoma with borderline malignant potential. Long-term follow-up is recommended due to the uncertain malignant potential.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13407015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Closure of Persistent Urinary Fistula After High-Grade Renal Trauma Using N-Butyl-2-Cyanoacrylate: A Case Report 使用n -丁基-2-氰基丙烯酸酯成功关闭高级别肾外伤后持续性尿瘘1例报告。

IF 0.5

IJU Case Reports Pub Date : 2026-07-27 DOI: 10.1002/iju5.70239

Yui Yamauchi, Masataka Kawamura, Yuji Koretsune, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Atsunari Kawashima, Yusuke Ono, Norio Nonomura

{"title":"Successful Closure of Persistent Urinary Fistula After High-Grade Renal Trauma Using N-Butyl-2-Cyanoacrylate: A Case Report","authors":"Yui Yamauchi, Masataka Kawamura, Yuji Koretsune, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Atsunari Kawashima, Yusuke Ono, Norio Nonomura","doi":"10.1002/iju5.70239","DOIUrl":"10.1002/iju5.70239","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Persistent urinary extravasation after high-grade renal trauma is uncommon but may require intervention. Minimally invasive, kidney-preserving options are particularly desirable in young patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>An 18-year-old man sustained blunt trauma in a motorcycle accident. Contrast-enhanced computed tomography revealed renal injury with urinary extravasation. Emergency transcatheter arterial embolization was performed for hemorrhage control. Despite subsequent ureteral stenting and percutaneous drainage, urinary leakage persisted. Fistulography demonstrated a small fistulous tract between the urinoma cavity and the lower calyx. Selective embolization using N-butyl-2-cyanoacrylate (NBCA) was performed, resulting in immediate resolution without complications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Selective NBCA embolization is a safe and minimally invasive treatment option for persistent urinary fistula after renal trauma.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13407014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Testis-Sparing Surgery for Metachronous Testicular Tumor Following Orchiectomy 睾丸切除术后异时性睾丸肿瘤的保睾丸手术。

IF 0.5

IJU Case Reports Pub Date : 2026-07-27 DOI: 10.1002/iju5.70232

Motoi Tobiume, Genya Nishikawa, Shigeyuki Aoki, Shingo Morinaga, Yasuhiro Yamada, Eriko Yamada, Yuya Buma, Hiromi Ogawa, Shigeki Nakane, Yoshiaki Yamada

{"title":"Testis-Sparing Surgery for Metachronous Testicular Tumor Following Orchiectomy","authors":"Motoi Tobiume, Genya Nishikawa, Shigeyuki Aoki, Shingo Morinaga, Yasuhiro Yamada, Eriko Yamada, Yuya Buma, Hiromi Ogawa, Shigeki Nakane, Yoshiaki Yamada","doi":"10.1002/iju5.70232","DOIUrl":"10.1002/iju5.70232","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>For metachronous bilateral testicular tumors occurring in young adulthood, the post-treatment quality of life must be considered when making treatment decisions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 46-year-old man presented to our hospital with a chief complaint of two bean-sized hard masses palpable in the right testis. At the age of 35, he had undergone inguinal orchiectomy for a tumor in the left testis, and the histopathological diagnosis was seminoma, with the stage pT1, N0, M0, S0. Adjuvant chemotherapy with carboplatin was not administered postoperatively. To preserve fertility, testis-sparing surgery was performed. The warm ischemic time during surgery was 32 min. Histopathological examination indicated seminoma, and biopsy did not reveal germ cell neoplasia in situ. His sexual function was preserved at 22 months after surgery; however, semen analysis revealed azoospermia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Testis-sparing surgery should be considered for metachronous bilateral testicular tumors, particularly for patients with tumor onset in young adulthood as it was thought to have the potential to maintain a favorable prognosis and fertility.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13407017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conversion to Pathological Complete Response by Enfortumab Vedotin in Metastatic Sarcomatoid Urothelial Carcinoma With Nectin-4 Expression: A Case Report 在伴有Nectin-4表达的转移性肉瘤样尿路上皮癌中，Enfortumab Vedotin转化为病理完全缓解：1例报告。

IF 0.5

IJU Case Reports Pub Date : 2026-07-27 DOI: 10.1002/iju5.70219

Sonin Chon, Shoichi Nagamoto, Takahisa Yamashita, Kenta Fujii, Kazuki Yokota, Kojiro Tachibana, Sachi Kitayama, Yohei Okada, Satoru Kawakami, Akihiro Yano

{"title":"Conversion to Pathological Complete Response by Enfortumab Vedotin in Metastatic Sarcomatoid Urothelial Carcinoma With Nectin-4 Expression: A Case Report","authors":"Sonin Chon, Shoichi Nagamoto, Takahisa Yamashita, Kenta Fujii, Kazuki Yokota, Kojiro Tachibana, Sachi Kitayama, Yohei Okada, Satoru Kawakami, Akihiro Yano","doi":"10.1002/iju5.70219","DOIUrl":"10.1002/iju5.70219","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Sarcomatoid urothelial carcinoma (UC) is an extremely rare and aggressive subtype with a poor prognosis. Reports on the efficacy of enfortumab vedotin (EV) in this subtype remain limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 74-year-old man presented with gross hematuria and was diagnosed with metastatic sarcomatoid UC of the urinary bladder with Nectin-4 expression. First-line chemotherapy with gemcitabine plus carboplatin therapy was initiated; however, lymph node metastases progressed. After second-line pembrolizumab therapy, new pulmonary and para-aortic lymph node metastases developed. Third-line EV therapy achieved a partial response in the bladder cancer and complete response in metastatic lesions. The patient subsequently underwent robot-assisted radical cystectomy with ileal conduit diversion, and pathological examination revealed no residual carcinoma (ypT0N0). He has remained disease-free for 30 months without additional therapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>EV may induce substantial and clinically meaningful responses in selected patients with metastatic sarcomatoid UC expressing Nectin-4, even after failure of platinum-based chemotherapy and immune checkpoint inhibition.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13406811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multimodal Treatment for Female Primary Urethral Carcinoma: A Three-Case Series Utilizing Robot-Assisted Radical Cystectomy and Extended Resection. 多模式治疗女性原发性尿道癌：三例机器人辅助根治性膀胱切除术和扩大切除术。

IF 0.5

IJU Case Reports Pub Date : 2026-07-26 eCollection Date: 2026-07-01 DOI: 10.1002/iju5.70229

Yuya Oishi, Hiromitsu Watanabe, Shinya Watanabe, Kyohei Watanabe, Yuto Matsushita, Keita Tamura, Daisuke Motoyama, Teruo Inamoto

{"title":"Multimodal Treatment for Female Primary Urethral Carcinoma: A Three-Case Series Utilizing Robot-Assisted Radical Cystectomy and Extended Resection.","authors":"Yuya Oishi, Hiromitsu Watanabe, Shinya Watanabe, Kyohei Watanabe, Yuto Matsushita, Keita Tamura, Daisuke Motoyama, Teruo Inamoto","doi":"10.1002/iju5.70229","DOIUrl":"10.1002/iju5.70229","url":null,"abstract":"<p><strong>Introduction: </strong>Primary urethral carcinoma (PUC) is a rare malignancy, particularly in females, with no established standard treatment. We herein examined the clinical outcomes of three female patients who underwent multimodal therapy with robot-assisted radical cystectomy (RARC) and extended surgical resection.</p><p><strong>Case presentation: </strong>Three female patients (45, 65, and 71 years) were diagnosed with PUC (adenocarcinoma, cT3N0M0; clear cell carcinoma, cT3N2M0; and squamous cell carcinoma, cT4N0M0). Two patients received cisplatin-based neoadjuvant chemotherapy. All patients underwent RARC with en bloc urethrectomy and extended resection of the anterior vaginal wall or pelvic fascia. One achieved a pathological complete response, one developed local recurrence due to a positive surgical margin, and two remained recurrence-free.</p><p><strong>Conclusion: </strong>Individualized multimodal strategies combining perioperative chemotherapy and extended surgical resection are crucial for managing locally advanced PUC in females.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":"e70229"},"PeriodicalIF":0.5,"publicationDate":"2026-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopic Transplant Nephrectomy Using a Combination of Intracapsular and Extracapsular Approaches for Graft Intolerance Syndrome in Failed Renal Allografts. 腹腔镜移植肾切除术采用囊内和囊外联合入路治疗同种异体肾移植失败的移植物不耐受综合征。

IF 0.5

IJU Case Reports Pub Date : 2026-07-26 eCollection Date: 2026-07-01 DOI: 10.1002/iju5.70237

Yuto Naroda, Atsuhiko Ochi, Ryutaro Fukagai, Maiko Shimogawa, Masatoshi Matsunami, Jun Yashima, Tomo Suzuki, Yu Oyama, Hirokazu Abe, Masayoshi Okumi

{"title":"Laparoscopic Transplant Nephrectomy Using a Combination of Intracapsular and Extracapsular Approaches for Graft Intolerance Syndrome in Failed Renal Allografts.","authors":"Yuto Naroda, Atsuhiko Ochi, Ryutaro Fukagai, Maiko Shimogawa, Masatoshi Matsunami, Jun Yashima, Tomo Suzuki, Yu Oyama, Hirokazu Abe, Masayoshi Okumi","doi":"10.1002/iju5.70237","DOIUrl":"10.1002/iju5.70237","url":null,"abstract":"<p><strong>Introduction: </strong>Transplant nephrectomy for graft intolerance syndrome is technically challenging because severe perirenal adhesions increase bleeding risk. Despite the increasing adoption of minimally invasive techniques, optimal laparoscopic strategies remain limited.</p><p><strong>Case presentation: </strong>A 49-year-old man developed pembrolizumab-induced graft intolerance syndrome (GIS) following surgery for native renal cell carcinoma. To enable safe continuation of immunotherapy, laparoscopic transplant nephrectomy was performed. Despite severe adhesions, a combined intracapsular and extracapsular approach enabled safe graft removal. Multiple feeding vessels were divided using a vessel-sealing device and soft coagulation, while avoiding extensive hilar dissection. Postoperative computed tomography confirmed complete resection of the allograph, with no radiologically evident residual tissue or postoperative complications.</p><p><strong>Conclusion: </strong>This hybrid laparoscopic approach is a safe, minimally invasive option for managing GIS with severe adhesions.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":"e70237"},"PeriodicalIF":0.5,"publicationDate":"2026-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13402014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ureteral Metastasis From Endometrial Carcinoma Mimicking Upper Tract Urothelial Carcinoma. 模拟上尿路上皮癌的子宫内膜癌输尿管转移。

IF 0.5

IJU Case Reports Pub Date : 2026-07-22 eCollection Date: 2026-07-01 DOI: 10.1002/iju5.70236

Masataka Kubo, Kazuhiro Takahashi, Hiroaki Arakawa, Shun Sato, Ria Kim, Hirokuni Takano, Takahiro Kimura, Jun Miki

{"title":"Ureteral Metastasis From Endometrial Carcinoma Mimicking Upper Tract Urothelial Carcinoma.","authors":"Masataka Kubo, Kazuhiro Takahashi, Hiroaki Arakawa, Shun Sato, Ria Kim, Hirokuni Takano, Takahiro Kimura, Jun Miki","doi":"10.1002/iju5.70236","DOIUrl":"10.1002/iju5.70236","url":null,"abstract":"<p><strong>Introduction: </strong>Ureteral metastasis from endometrial carcinoma is extremely rare. We report a case identified at the time of the initial diagnosis of endometrial carcinoma.</p><p><strong>Case presentation: </strong>A 64-year-old woman presented with suspected endometrial carcinoma. Contrast-enhanced computed tomography revealed hydronephrosis and a left ureteral mass suggestive of upper tract urothelial carcinoma (UTUC). Urine cytology showed malignant cells, but ureteroscopy was inconclusive. Because UTUC can affect management and prognosis, simultaneous surgery, including nephroureterectomy, was performed. Histopathological examination revealed ureteral adenocarcinoma morphologically similar to endometrial carcinoma. Immunohistochemical staining demonstrated PAX8 positivity, supporting the diagnosis of metastatic endometrial carcinoma. The final diagnosis was stage IVB endometrial carcinoma.</p><p><strong>Conclusion: </strong>Ureteral metastasis from endometrial carcinoma is extremely uncommon and may closely mimic UTUC on imaging, making preoperative diagnosis difficult.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":"e70236"},"PeriodicalIF":0.5,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete Response to Concurrent Triplet Therapy in Low-Volume Metastatic Hormone-Sensitive Prostate Cancer: A Case Report. 小体积转移性激素敏感前列腺癌并发三联疗法的完全缓解：1例报告。

IF 0.5

IJU Case Reports Pub Date : 2026-07-17 eCollection Date: 2026-07-01 DOI: 10.1002/iju5.70231

Takashi Fujita, Koki Kobayashi, Gaku Hayashi, Shunsuke Kamijo, Fumihiro Ito

{"title":"Complete Response to Concurrent Triplet Therapy in Low-Volume Metastatic Hormone-Sensitive Prostate Cancer: A Case Report.","authors":"Takashi Fujita, Koki Kobayashi, Gaku Hayashi, Shunsuke Kamijo, Fumihiro Ito","doi":"10.1002/iju5.70231","DOIUrl":"10.1002/iju5.70231","url":null,"abstract":"<p><strong>Introduction: </strong>Triplet therapy with androgen deprivation therapy (ADT), an androgen receptor pathway inhibitor, and docetaxel improves survival in metastatic hormone-sensitive prostate cancer (mHSPC), but its role in low-volume disease remains unclear.</p><p><strong>Case presentation: </strong>A 68-year-old man presented with dysuria and a PSA increase to 34.49 ng/mL. Imaging revealed a prostate tumor extending into the bladder, right obturator lymph node metastasis, and a bone lesion. Biopsy showed Gleason score 5 + 5 prostate adenocarcinoma (cT4N1M1b low-volume mHSPC). Concurrent triplet therapy with ADT, darolutamide, and docetaxel was initiated. PSA decreased to 0.1 ng/mL within 2 months, and imaging at 4.5 months demonstrated a radiological complete response. At the latest follow-up (7 months), the PSA remained below 0.03 ng/mL without progression to CRPC.</p><p><strong>Conclusion: </strong>Concurrent triplet therapy may achieve complete response in selected patients with aggressive low-volume mHSPC.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 4","pages":"e70231"},"PeriodicalIF":0.5,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13378404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148581224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0