Editorial Comment From Dr. Chelsea and Dr. Ranjana to Zinner Syndrome Presenting With Chronic Pelvic Pain and Ejaculatory Dysfunction

We read the report by Patil et al. with great interest; it effectively showcases the utility of conservative management in mildly symptomatic cases of Zinner syndrome, reinforcing the clinical principle of observation over intervention in the absence of disease progression [1]. Nevertheless, it offers a valuable context for reflecting on how surveillance strategies can evolve in such congenital anomalies. The decision to initiate empirical antibiotics and NSAIDs is clinically sound, yet future protocols might consider refining indications for antimicrobial use based on inflammatory markers or seminal plasma analysis, tools that can differentiate infectious from obstructive discomfort, especially in the absence of overt urinary tract infection [2, 3].

Another area worth discussing lies in the parameters guiding longitudinal follow-up. While 6-monthly semen analysis and imaging were proposed, outlining more specific clinical or biochemical triggers for potential escalation could enhance the generalizability of such a protocol. For example, establishing reference changes in semen motility or testicular volume may better anchor treatment thresholds.

The imaging findings were well articulated and provided excellent diagnostic clarity. However, recent studies suggest that seminal vesicle cysts with high proteinaceous content may benefit from biochemical analysis if aspiration is indicated in future cases [4]. Even when surgery is deferred, evolving imaging markers, such as cyst wall thickening or atypical signal patterns, might be integrated into future conservative frameworks to ensure safety.

This case demonstrates commendable clarity in the approach and contributes to an underrepresented segment of the urological literature. Its insights can further inform the development of structured, evidence-based algorithms for conservative management in young patients with fertility considerations.

The authors have nothing to report.

The authors have nothing to report.

The authors declare no conflicts of interest.