Oral and maxillofacial surgery最新文献

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Risk factors for delayed-onset infection after lower third molar surgery: a retrospective case-control study. 下第三磨牙手术后迟发性感染的危险因素:一项回顾性病例对照研究。
Oral and maxillofacial surgery Pub Date : 2025-06-18 DOI: 10.1007/s10006-025-01420-9
Nongpanga Jitpreeda, Chonatee Chinkrua
{"title":"Risk factors for delayed-onset infection after lower third molar surgery: a retrospective case-control study.","authors":"Nongpanga Jitpreeda, Chonatee Chinkrua","doi":"10.1007/s10006-025-01420-9","DOIUrl":"https://doi.org/10.1007/s10006-025-01420-9","url":null,"abstract":"<p><strong>Purpose: </strong>Delayed-onset infection (DOI) is an uncommon postoperative complication of lower third molar surgery, typically occurring around one month after the procedure. This study aimed to identify risk factors for DOI to support improved prevention and management.</p><p><strong>Methods: </strong>A retrospective case-control study was conducted using records from patients who underwent lower third molar surgery between January 2015 and December 2022. Seventy-four cases of DOI were identified and matched to 296 controls in a 1:4 ratio. Univariable and conditional multivariable logistic regression analyses were employed to identify significant risk factors.</p><p><strong>Results: </strong>The incidence of DOI was 0.66%, with a mean onset of 36.5 days postoperatively. Univariable analysis revealed nine potential risk factors, mesioangular and horizontal impaction, including Pell & Gregory classification Class III, Position B and C, Nolla's stage ≤ 8, Ganss ratio ≤ 0.5, bone retention, and postgraduate/experienced operator. However, multivariable analysis identified three independent predictors: Pell & Gregory classification Class III (OR = 5.89, 95% CI: 1.52-22.79), Pell & Gregory classification Position B (OR = 4.19, 95% CI: 1.70-10.31), and postgraduate/experienced operator (OR = 4.54, 95% CI: 1.59-12.98).</p><p><strong>Conclusions: </strong>Postgraduate/experienced operator, Pell & Gregory class III, and position B were identified as significant risk factors for DOI in our institution. Although the incidence is low, the potential impact on patient quality of life highlights the importance of early recognition, risk stratification, and close postoperative follow-up in high-risk individuals.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"124"},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144328489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of local and systemic photobiomodulation in only single-implant insertion: a randomized clinical trial. 评估局部和全身光生物调节仅在单一植入物插入:一项随机临床试验。
Oral and maxillofacial surgery Pub Date : 2025-06-18 DOI: 10.1007/s10006-025-01424-5
Daniel Sartorelli Pucca, Sérgio Luiz Pinheiro
{"title":"Evaluation of local and systemic photobiomodulation in only single-implant insertion: a randomized clinical trial.","authors":"Daniel Sartorelli Pucca, Sérgio Luiz Pinheiro","doi":"10.1007/s10006-025-01424-5","DOIUrl":"10.1007/s10006-025-01424-5","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of local and systemic photobiomodulation (PBM-T) after dental surgery for single-tooth implant placement in healed sites.</p><p><strong>Materials and methods: </strong>Fifty-one patients were included and randomly assigned to 2 groups: PBM-T (n = 26), with local and systemic PBM-T application immediately after implant site drilling and suturing; and control group (n = 25), with PBM-T simulation. The parameters used for local PBM-T were low-intensity laser diode (Therapy EC, DMC, São Carlos, SP, Brazil), 1 J of energy per point for 10 s, energy density of 10.20 J/cm², output spot of 0.09842 cm², infrared wavelength of 808 nm and power of 100 mW/cm². Systemic PBM-T was performed using the same low-intensity laser diode. Patients received a single 10-minute systemic transdermal irradiation over the radial artery immediately after suturing, with a total energy of 60 J, energy density of 306.12 J/cm², wavelength of 660 nm, and power of 100 mW. Postoperative pain via visual analog scale (VAS), analgesic use, healing, and quality of life using the Oral Health Impact Profile (OHIP-14) were assessed. Results were analyzed using the Kruskal-Wallis test (Student-Newman-Keuls) and chi-square test.</p><p><strong>Results: </strong>There was no significant difference in VAS pain scores between the control and PBM-T groups (p = 0.5217). The number of analgesics taken by participants in the control group was 2.37 times higher than that taken by the PBM-T group. A significant difference in healing grades was observed between the control and PBM-T groups at both the 3-day and 7-day assessments (p = 0.0029 and p = 0.0002, respectively), with the PBM-T group demonstrating marked improvement. There was no negative impact on quality of life at any point after implant placement in the PBM-T group, as all OHIP-14 scores remained lower than those obtained before surgery.</p><p><strong>Conclusions: </strong>The combined use of local and systemic PBM-T decreased the need for postoperative analgesics, enhanced postoperative healing, and improved quality of life for patients undergoing single-tooth implant placement in healed sites.</p><p><strong>Clinical relevance: </strong>The clinical application of systemic PBM-T enhances the effects of local PBM-T after dental surgery for implant placement.</p><p><strong>Trial registration number: </strong>Brazilian Registry of Clinical Trials (ReBEC), with the identifier RBR-7f42fs5, on Nov 30, 2023.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"125"},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144328488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pain control and adverse effects of parecoxib after wisdom teeth surgery: a quantitative systematic review. 智齿手术后帕瑞昔布的疼痛控制和不良反应:一项定量系统评价。
Oral and maxillofacial surgery Pub Date : 2025-06-17 DOI: 10.1007/s10006-025-01416-5
Othoniel Hugo Aragon-Martinez, Eduardo Gómez-Sánchez, Ronell Bologna-Molina, Nelly Molina-Frechero, Sandra López-Verdín, Nicolás Serafín-Higuera, Juan Manuel Guzmán-Flores, Maikel Hermida-Rojas, Mario Alberto Isiordia-Espinoza
{"title":"Pain control and adverse effects of parecoxib after wisdom teeth surgery: a quantitative systematic review.","authors":"Othoniel Hugo Aragon-Martinez, Eduardo Gómez-Sánchez, Ronell Bologna-Molina, Nelly Molina-Frechero, Sandra López-Verdín, Nicolás Serafín-Higuera, Juan Manuel Guzmán-Flores, Maikel Hermida-Rojas, Mario Alberto Isiordia-Espinoza","doi":"10.1007/s10006-025-01416-5","DOIUrl":"10.1007/s10006-025-01416-5","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"123"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Kinesio taping and/or transdermal diclofenac patch reduce postoperative pain and swelling after open reduction and internal fixation of mandibular angle fractures? 肌内效贴片和/或双氯芬酸透皮贴片能减轻下颌角骨折切开复位内固定术后疼痛和肿胀吗?
Oral and maxillofacial surgery Pub Date : 2025-06-17 DOI: 10.1007/s10006-025-01404-9
Sai Prasanna Patruni, Shivaji Raju, Divya Puvvada, Kishore Moturi, Anil Budumuru, Meghana Vadupu
{"title":"Does Kinesio taping and/or transdermal diclofenac patch reduce postoperative pain and swelling after open reduction and internal fixation of mandibular angle fractures?","authors":"Sai Prasanna Patruni, Shivaji Raju, Divya Puvvada, Kishore Moturi, Anil Budumuru, Meghana Vadupu","doi":"10.1007/s10006-025-01404-9","DOIUrl":"10.1007/s10006-025-01404-9","url":null,"abstract":"<p><strong>Purpose: </strong>Postoperative pain and facial swelling are frequent complications following open reduction and internal fixation (ORIF) of mandibular angle fractures, impacting recovery and early postoperative quality of life. This study assesses the effectiveness of Kinesio taping (KT) and transdermal diclofenac patches (TDP), both individually and in combination, in managing postoperative pain and swelling. By comparing these non-invasive interventions, we aim to determine their role in enhancing patient comfort and postoperative recovery.</p><p><strong>Methods: </strong>A triple-blind randomised controlled trial was conducted at a tertiary trauma centre in rural South India, enrolling 60 patients (18-55 years) with isolated unilateral mandibular angle fractures. Patients were randomly assigned to KT + TDP, KT alone, or TDP alone and Intramuscular Diclofenac (IM-control) groups. Primary outcomes measured were postoperative swelling (measured using a 5-linetechnique), pain (10-point Visual Analog Scale), and the amount of rescue analgesics consumed, analysed using ANOVA and post hoc tests (P < 0.05).</p><p><strong>Results: </strong>Swelling peaked on postoperative day 2, with the KT + TDP group showing significantly less swelling than other groups (P < 0.05). Pain scores were highest in the KT-only group (P = 0.00), while TDP and IM groups showed comparable pain reduction. Statistical analysis confirmed the significant differences among the groups (p < 0.05).</p><p><strong>Conclusion: </strong>The combination of a transdermal diclofenac patch and Kinesio tape offers the most effective relief, significantly reducing postoperative pain and swelling, indicating a synergistic effect. Integrating these non-invasive modalities into postoperative care protocols can enhance patient comfort and recovery following ORIF of mandibular angle fractures.</p><p><strong>Trial registration: </strong>This trial was registered in Clinical Trials Registry of India, on 29/07/2021 holding Registration number CTRI/2021/07/035272 and was registered prospectively.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"122"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative management of pediatric mandibular fractures with cap splints- A systematic review. 用帽形夹板保守治疗儿童下颌骨骨折的系统综述。
Oral and maxillofacial surgery Pub Date : 2025-06-14 DOI: 10.1007/s10006-025-01405-8
Namita Kumari, Jhunjhunwala Garima, Morankar Rahul, Nitesh Tewari, Vijay Prakash Mathur, Kalpana Bansal
{"title":"Conservative management of pediatric mandibular fractures with cap splints- A systematic review.","authors":"Namita Kumari, Jhunjhunwala Garima, Morankar Rahul, Nitesh Tewari, Vijay Prakash Mathur, Kalpana Bansal","doi":"10.1007/s10006-025-01405-8","DOIUrl":"10.1007/s10006-025-01405-8","url":null,"abstract":"<p><strong>Background: </strong>Mandible is the second most common bone involved among pediatric facial fractures, and the open reduction and internal fixation (ORIF) technique used for its management results in faster bone remodeling and quicker functional recovery. However, it can lead to damage to the periosteum and surrounding tooth buds, and may require a second surgery for removal. Therefore, conservative methods always remain mainstay for management among pediatric patients. This systematic review evaluates the use of cap splints in managing pediatric mandibular fractures and compares this approach with other closed reduction methods.</p><p><strong>Methods: </strong>A priori protocol was prepared, and registered in the International Prospective Register of Systematic Reviews (CRD42024531959). A comprehensive literature search was performed electronically in PubMed, EMBASE, Web of Science, and Scopus till December 31, 2024, whereas a grey literature search was carried out on Google Scholar and open grey. Two reviewers independently assessed the methodological quality of the included studies by using the appropriate Joanna Briggs Institute's (JBI) critical appraisal checklist for case reports, case series, and retrospective cohort studies. For a prospective cohort study, the risk of bias in non-randomized studies of intervention was used for quality assessment.</p><p><strong>Result: </strong>The database search revealed 2308 records, and 48 records were obtained from grey literature and citation search. A total of 47 studies (28 case reports, 13 case series, three retrospective studies, and three prospective non-randomized interventions) were finally included in the review. The different modalities used were cap splint with luting cement, circum-mandibular wiring, interdental wiring, and arch bar fixation. Among the included studies, one case report and three case series had a high risk of bias. Similarly, all retrospective studies had a high risk of bias.</p><p><strong>Conclusion: </strong>Cap splint can be recommended as a treatment option for non-displaced pediatric mandibular fractures that do not involve the condyle. Luting cement can be used as an alternative to circum-mandibular wiring.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"121"},"PeriodicalIF":0.0,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the operator's generational cohort influence the accuracy of orthodontic miniscrews insertion in the palatine vault in dynamic computer-guided surgery? A randomized prospective study. 在动态计算机引导手术中,操作者的世代是否会影响正畸微钉插入腭穹窿的准确性?一项随机前瞻性研究。
Oral and maxillofacial surgery Pub Date : 2025-06-10 DOI: 10.1007/s10006-025-01414-7
Davide Brilli, Matteo Giansanti, Michele Cassetta
{"title":"Does the operator's generational cohort influence the accuracy of orthodontic miniscrews insertion in the palatine vault in dynamic computer-guided surgery? A randomized prospective study.","authors":"Davide Brilli, Matteo Giansanti, Michele Cassetta","doi":"10.1007/s10006-025-01414-7","DOIUrl":"10.1007/s10006-025-01414-7","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate intergenerational differences in miniscrew placement accuracy in the palatine vault using dynamic computer-assisted surgery (d-CAS), and to assess the correlation between the number of surgeries, and both accuracy variables and procedure duration.</p><p><strong>Materials and methods: </strong>72 subjects were enrolled and for each two miniscrews were inserted in the paramedian region via d-CAS (144 overall). Subjects were randomly allocated into three groups according to the operator's generation: Group A (Generation X), Group B (Generation Y), and Group C (Generation Z). CBCT scans were superimposed to evaluate five variables: Entry-3D, Entry-2D, Apex-3D, Apex-Vertical, and angular deviation. Procedure duration was calculated. Statistical analyses included descriptive statistics, Shapiro-Wilk, ANOVA, Kruskal-Wallis, Tukey and Dunn's tests and Pearson Correlation. P-value was set at ≤ 0.05.</p><p><strong>Results: </strong>ANOVA test demonstrated significant differences between the three groups in Entry-3D (P < 0.001), Entry-2D (P < 0.001), and Apex-3D (P = < 0.001) parameters, while Kruskal-Wallis test found a significant difference in angular deviation (P = 0.003). Post-hoc comparison revealed significant differences between groups A and C, and groups B and C. Pearson correlation indicated a negative correlation between intervention time and number of surgeries.</p><p><strong>Conclusions: </strong>Miniscrew insertion using d-CAS is operator-dependent, and the generational cohort of the operator is a factor that influences certain accuracy parameters. There is a correlation between the progression of surgeries and a reduction in the time employed. Understanding the impact of generational differences can encourage the use of digital technologies for novices in clinical practice.</p><p><strong>Clinical trial number: </strong>NCT06661551 (clinicaltrials.gov; 10/25/2024).</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"120"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can acupuncture be a viable method for pain control after lower third molar removal? A systematic review with meta-analysis. 针灸是否可以作为下第三磨牙拔除后疼痛控制的可行方法?荟萃分析的系统综述。
Oral and maxillofacial surgery Pub Date : 2025-06-06 DOI: 10.1007/s10006-025-01415-6
Kayo Costa Alves, Pedro Henrique da Hora Sales, Paulo Goberlânio de Barros Silva, Kristiana Cerqueira Mousinho
{"title":"Can acupuncture be a viable method for pain control after lower third molar removal? A systematic review with meta-analysis.","authors":"Kayo Costa Alves, Pedro Henrique da Hora Sales, Paulo Goberlânio de Barros Silva, Kristiana Cerqueira Mousinho","doi":"10.1007/s10006-025-01415-6","DOIUrl":"10.1007/s10006-025-01415-6","url":null,"abstract":"<p><strong>Introduction: </strong>Surgery to remove lower third molars is usually associated with events such as pain, swelling and trismus, thus increasing postoperative morbidity. The control of these signs and symptoms is essential for a quick recovery of the patient.</p><p><strong>Purpose: </strong>The objective of this study was to determine whether acupuncture is effective in controlling pain in lower third molar surgeries.</p><p><strong>Methods: </strong>A systematic review was carried out by two independent researchers and the selection of studies took place according to the inclusion and exclusion criteria previously established. The main outcome measure was the analysis of pain in the postoperative period. Data analysis included risk of bias assessment (RoB 2 Cochrane) and meta-analysis with heterogeneity based on random effects I² and 95% confidence.</p><p><strong>Results: </strong>In the initial results, 717 articles were found, and 6 studies were selected for analysis in this review. The results of the meta-analysis showed that there was a significant reduction in pain scores after 2 h (p < 0.001), 18 h (p = 0.008), 24 h (p < 0.001), 48 h (< 0.001) and 72 h (p < 0.001) in favor of the acupuncture group.</p><p><strong>Conclusions: </strong>According to the results of this study, acupuncture has shown an effective result in reducing pain, however due to the heterogeneity of studies and the low level of evidence, it is not possible to determine whether acupuncture is a viable method for pain control after lower third molar surgery. New standardized and controlled studies are needed to confirm the efficacy of this therapy.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"119"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free chimeric LD + SA flap for tongue and suprahyoid muscles reconstruction after total glossectomy. 游离嵌合LD + SA瓣在舌骨全切术后舌骨上肌重建中的应用。
Oral and maxillofacial surgery Pub Date : 2025-06-05 DOI: 10.1007/s10006-025-01418-3
Alexander V Mordovskiy, Andrey P Polyakov, Andrey D Kaprin, Mikhail V Ratushnyy, Irina V Novikova
{"title":"Free chimeric LD + SA flap for tongue and suprahyoid muscles reconstruction after total glossectomy.","authors":"Alexander V Mordovskiy, Andrey P Polyakov, Andrey D Kaprin, Mikhail V Ratushnyy, Irina V Novikova","doi":"10.1007/s10006-025-01418-3","DOIUrl":"https://doi.org/10.1007/s10006-025-01418-3","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to report the functional outcomes of patients who underwent total or near total glossectomy for oral SCC reconstructed with a chimeric latissimus dorsi and serratus anterior (LD + SA) flap.</p><p><strong>Methods: </strong>Thirty-two patients with tongue cancer, with a mean age of 48.8 years, were included in the study. All patients underwent total or near total glossectomy and subsequent reconstruction with chimeric LD + SA flap. Swallowing and speech functions were measured and prospectively recorded pre- and 3,6 and 12 months postoperatively. Patient-reported outcomes were measured using the Speech Handicap Index (SHI), M.D. Anderson Dysphagia Inventory (MDADI), and EORTC-QLQ-H&N 35 score at 12 months. Additionally, volume reduction in the flaps was measured.</p><p><strong>Results: </strong>The mean follow-up period was 21 months (range, 2-67 months). The flaps were successfully placed in 30 cases. The total success rate was 93.8% (30/32). In 25 cases (83,3%), a positive functional outcome was recorded, defined as the achievement of an adequate swallowing and speech ability. The swallowing evaluation study revealed that 83% (25/30) of patients experienced bolus transit. Speech function was assessed 3, 6, and 12 months prospectively by speech therapist, with patient-reported SHI outcomes at 12 months. Speech intelligibility was good in 16,7% of cases (5/30, mean SHI 29.18, SD 16.36) acceptable in 56,7% (17/30, mean SHI 51.14, SD 19.8) and poor intelligibility in 26,7% (8/30, mean SHI 65.62 SD 9.8) at 12 months. Mean MDADI score was 84.5 (SD 12.15), indicating good swallowing function. Decannulation was possible in 25 of the 30 patients (83,3%).</p><p><strong>Conclusion: </strong>The chimeric LD + SA free flap represents a feasible option for tongue reconstruction after salvage glossectomy, with promising functional outcomes and low donor-side morbidity. This approach significantly improved the patients' oral functions and quality of life.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"118"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the effect of nano-hydroxyapatite/silica gel bone graft and/or hemodialysate paste on the regeneration and nano-mechanical properties of calvarial bone in gammairradiated albino rats. 纳米羟基磷灰石/硅胶骨移植物和/或血液透析液膏剂对γ辐射白化大鼠颅骨再生和纳米力学性能的影响。
Oral and maxillofacial surgery Pub Date : 2025-06-04 DOI: 10.1007/s10006-025-01413-8
Noha S Zein, Sara El Moshy, Mohammed Khashaba, Eman M F El-Maghraby, Engy R Rashed, Dalia M Abdel-Hamid
{"title":"Evaluation of the effect of nano-hydroxyapatite/silica gel bone graft and/or hemodialysate paste on the regeneration and nano-mechanical properties of calvarial bone in gammairradiated albino rats.","authors":"Noha S Zein, Sara El Moshy, Mohammed Khashaba, Eman M F El-Maghraby, Engy R Rashed, Dalia M Abdel-Hamid","doi":"10.1007/s10006-025-01413-8","DOIUrl":"10.1007/s10006-025-01413-8","url":null,"abstract":"<p><strong>Purpose: </strong>Evaluating the effect of synthetic nano-hydroxyapatite/silica gel bone substitute and/or hemodialysate on gamma irradiated bone regeneration and bone nano-mechanical properties in rat model.</p><p><strong>Methods: </strong>Seventy adult male Wistar albino rats (total of 70 defects, 1 defect/rat) were randomly divided into five groups (14 rats/group); 4 irradiated groups; control (Ir-C) without any treatment, NanoBone<sup>®</sup>-treated (Ir-N), Solcoseryl<sup>®</sup>-treated (Ir-S), NanoBone<sup>®</sup> + Solcoseryl<sup>®</sup>-treated (Ir-NS) groups, and one non-irradiated NanoBone<sup>®</sup> + Solcoseryl<sup>®</sup>-treated (Nr-NS) group. Each rat's calvarium was subjected to a single dose of gamma radiation (12 Gy) followed by a single critical-sized defect creation. Defects were then filled with the assigned treatments except the Ir-C group. Rats were euthanized after 4 weeks. Hematoxylin and Eosin, Masson's Trichrome staining and nano-indentation were performed for histologic and nano-mechanical properties assessment of specimens.</p><p><strong>Results: </strong>Scattered thin new bone trabeculae with randomly arranged fine collagen fibrils and extravasated blood were evident in Ir-C group, while thicker new bone trabeculae, well-organized collagen fibers and new blood vessels were observed in all treated groups. Ir-C group showed the lowest significant bone area percent, nano-hardness and indentation modulus values, while Nr-NS group possessed the highest significant percent and values. Ir-C group showed the highest significant indentation modulus to nano-hardness ratio followed by Ir-S group, while the lowest ratios were obtained by the rest of the groups with no significance.</p><p><strong>Conclusions: </strong>The combination of synthetic nano-hydroxyapatite/silica gel bone substitute and hemodialysate enhanced the quality and quantity of regenerated gamma-irradiated rats' bones.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"116"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12134040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144218573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of recovery in maxillofacial surgical patients undergoing intravenous conscious sedation using PSI monitoring. 应用PSI监测评估颌面部外科手术患者静脉清醒镇静的恢复情况。
Oral and maxillofacial surgery Pub Date : 2025-06-04 DOI: 10.1007/s10006-025-01408-5
Ramita Sood, Balubhai Ram, Mustafa Kurani, Anupama Chauhan, Nisarg Trivedi
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