{"title":"Locoregional recurrence patterns in surgically treated stage III and IV oral squamous cell carcinoma: a prospective observational study.","authors":"Ridham Shah, Anupam Lahiri, Suchita Chowdhury","doi":"10.1007/s10006-025-01458-9","DOIUrl":"10.1007/s10006-025-01458-9","url":null,"abstract":"<p><strong>Background: </strong>Advanced oral squamous cell carcinoma demonstrates high locoregional recurrence despite multimodal therapy. This study identified clinical and pathological predictors of recurrence in surgically treated stage III-IV OSCC.</p><p><strong>Methods: </strong>This prospective observational study analyzed 260 patients with stage III-IV OSCC treated at a tertiary cancer center (2019-2021). Clinicopathological parameters including tumor staging, lymph node ratio, differentiation, margins, depth of invasion, extracapsular extension, lymphovascular invasion, perineural invasion and treatment factors were evaluated. Multivariate Cox regression identified independent predictors. ROC curve analysis determined optimal cutoffs.</p><p><strong>Results: </strong>Locoregional recurrence occurred in 44/260 patients (16.92%). Univariate analysis revealed significant associations with LNR (p < 0.00001), ECE (p < 0.00001), LVI (p = 0.003), positive lymph nodes (p = 0.001), radiotherapy completion (p = 0.009), and surgery to radiation interval (p = 0.0002). Multivariate analysis identified three independent predictors: PNI (OR 18.42, 95% CI 5.43-62.46, p < 0.01), ECE (OR 8.17, 95% CI 1.51-44.33, p = 0.01), and positive node count (OR 1.64, 95% CI 1.21-2.22, p < 0.01). ROC analysis established ≥ 2 positive nodes as optimal cutoff (AUC = 0.844), stratifying patients into low-risk (< 2 nodes: 3.4% recurrence) and high-risk (≥ 2 nodes: 44.7% recurrence) groups. T-stage, margins, depth of invasion, and differentiation showed no significant association.</p><p><strong>Conclusions: </strong>PNI, ECE, and positive lymph node count independently predict locoregional recurrence in advanced OSCC. Our risk stratification model incorporating these factors enables personalized surveillance and adjuvant therapy intensification. Radiotherapy should commence within six weeks of surgery for optimal outcomes.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"160"},"PeriodicalIF":1.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145133359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of Fitzpatrick skin type on Scar maturation following transcutaneous infraorbital approach: a prospective comparative clinical study.","authors":"Bhavuk Vanza, Anuj Jain, Neha Khare, Yash Merchant","doi":"10.1007/s10006-025-01457-w","DOIUrl":"10.1007/s10006-025-01457-w","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the impact of Fitzpatrick skin type on postoperative scar esthetics following infraorbital fracture reconstruction using a transcutaneous subtarsal approach, with emphasis on long-term scar maturation and patient complexion.</p><p><strong>Methods: </strong>A prospective clinical study was conducted on 27 patients undergoing open reduction and internal fixation of infraorbital rim fractures via the subtarsal approach. Fitzpatrick skin typing was performed preoperatively and categorized into three groups: Group I (Types I-III), Group II (Types IV-V), and Group III (Type VI). Scars were evaluated at day 10, 1 month, and 12 months using a 10-point Visual Analogue Scale (VAS), independently rated by a blinded maxillofacial surgeon and dermatologist. Statistical analyses included the Wilcoxon signed-rank test, Kruskal-Wallis H test, and Cohen's kappa for inter-rater reliability.</p><p><strong>Results: </strong>Out of 27 patients, 23 completed the 12-month follow-up. All groups demonstrated improvement in VAS scores over time; however, Groups II and III showed significantly better esthetic outcomes at 12 months (mean VAS scores: 9.81 and 9.83, respectively) compared to Group I (8.60) (p < 0.05). Group I exhibited slower scar integration and greater long-term visibility. Inter-rater agreement was excellent (κ = 0.84). No cases of keloid or hypertrophic scar formation were observed.</p><p><strong>Conclusion: </strong>Fitzpatrick skin type significantly influences scar maturation following infraorbital surgery. Darker skin types (IV-VI) demonstrate superior esthetic outcomes. Integrating skin phototyping into preoperative assessment may guide personalized surgical planning and optimize scar-related patient satisfaction.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"156"},"PeriodicalIF":1.8,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paulo Ricardo Elias de Melo, Wliana Pontes de Lima, Israel Leal Cavalcante, Vitória Maria Sousa Cruz, Roberta Barroso Cavalcante, Eveline Turatti, Sebastião Silvério Sousa-Neto, Elismauro Francisco Mendonça, Sara Juliana de Abreu de Vasconcellos, Paulo Almeida Júnior, Cassiano Francisco Weege Nonaka, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Pollianna Muniz Alves, Bruno Augusto Benevenuto de Andrade, John Lennon Silva Cunha
{"title":"Retraction Note: Clinicopathologic and imaging features of odontogenic myxomas: a multi-institutional study.","authors":"Paulo Ricardo Elias de Melo, Wliana Pontes de Lima, Israel Leal Cavalcante, Vitória Maria Sousa Cruz, Roberta Barroso Cavalcante, Eveline Turatti, Sebastião Silvério Sousa-Neto, Elismauro Francisco Mendonça, Sara Juliana de Abreu de Vasconcellos, Paulo Almeida Júnior, Cassiano Francisco Weege Nonaka, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Pollianna Muniz Alves, Bruno Augusto Benevenuto de Andrade, John Lennon Silva Cunha","doi":"10.1007/s10006-025-01465-w","DOIUrl":"https://doi.org/10.1007/s10006-025-01465-w","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"159"},"PeriodicalIF":1.8,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Mushtaq, Amir A Majeed, Saher Sultan, Rehana Yasmeen, Faryal Sharifullah, Yasir Rehman Khattak, Nasar Shah, Iftikhar Ahmad
{"title":"Mandibular reconstruction with custom-made extended total temporomandibular joint prosthesis after resection of ameloblastoma:A systematic review.","authors":"Muhammad Mushtaq, Amir A Majeed, Saher Sultan, Rehana Yasmeen, Faryal Sharifullah, Yasir Rehman Khattak, Nasar Shah, Iftikhar Ahmad","doi":"10.1007/s10006-025-01455-y","DOIUrl":"10.1007/s10006-025-01455-y","url":null,"abstract":"<p><strong>Objectives: </strong>Ameloblastoma (AB) are aggressive odontogenic tumors, often treated with wide marginal resection and concurrent reconstruction. Extended total temporomandibular joint replacement (eTMJR) prosthesis is a viable treatment option for reconstruction of large defects caused by resection of AB tumors. The objective of this study was to systematically review the utilization and effectiveness of eTMJR prosthesis in treating patients with AB tumors.</p><p><strong>Methods: </strong>A detail search in Web of Science, Medline/PubMed, Google Scholar and Embase identified studies reporting AB patients who underwent implantation of eTMJR prosthesis. Studies reporting the use of eTMJR prosthesis in the management of AB tumors were eligible, with no restriction of the study type, language or year of publication and patient's demographics. Quality assessment of the selected case reports and case series was carried out with the 13 Domains (30 Items) of the CARE checklist, using a scoring scale of \"0\" (No/ non-adherence), \"1\" (Yes/ adherence) and \"2\" (unclear). The completeness of reporting (COR) score was determined as the ratio of \"yes\" responses to \"total\" (i.e., yes + no + unclear) responses.</p><p><strong>Results: </strong>A total of 27 studies were selected for analysis, including 15 case reports, 06 case series and 06 retrospective cohort studies. These studies presented 41 patients of AB who received eTMJR prosthesis. The patients' mean age was 37.8 ± 14.9 (range: 14-72, median: 36) years, whereas the mean follow-up period was 19.7 ± 20.3 (range: 1-84, median 12) months. The majority of studies did not document all clinically relevant data regarding patient clinical presentation, surgical procedures, long-term follow-up and post-operative complications. The mean ± SD (range, median) COR score for all case reports/ series was 61.7 ± 23.5 (4.0-100, 64.0) %.</p><p><strong>Conclusion: </strong>The use of eTMJR prosthesis in the management of AB tumors has demonstrated promising treatment outcome in case reports/ series. However, large cohort randomized controlled trials are essential to establish their therapeutic efficacy.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"157"},"PeriodicalIF":1.8,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osseodensification by Densah burs in combination with activated plasma albumin gel for transcrestal maxillary sinus lifting with simultaneous implant placement.","authors":"Esraa Salem Kamal, Ahmed Shaaban, Lydia Melek","doi":"10.1007/s10006-025-01459-8","DOIUrl":"10.1007/s10006-025-01459-8","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the clinical and radiographic outcomes of transcrestal maxillary sinus lifting using Densah burs in combination with activated plasma albumin gel (APAG) during simultaneous implant placement in cases with severely limited residual bone height (3-5 mm).</p><p><strong>Methods: </strong>A total of six patients with missing posterior maxillary teeth and insufficient alveolar bone height were treated using the osseodensification technique with Densah burs and APAG. CBCT scans were obtained preoperatively and six months postoperatively to evaluate changes in bone height and peri-implant bone density. Bone density was estimated using CBCT gray values derived from OnDemand 3D software, recognizing that these values provide relative rather than absolute measurements and are subject to inherent limitations.</p><p><strong>Results: </strong>No post-operative complications were recorded, and the sinus membrane remained intact in all cases. After six months, a statistically significant bone height gain was observed (mean 5.28 ± 0.70 mm; p < 0.001), along with a significant increase in bone density (mean difference 255.15 ± 95.69 HU; p < 0.001). Implant stability showed no statistically significant difference between primary and secondary ISQ values (mean difference 1.17 ± 4.31; p = 0.54).</p><p><strong>Conclusion: </strong>The combined use of Densah burs and activated plasma albumin gel for transcrestal sinus lifting appears to be a safe and minimally invasive technique, promoting substantial bone height gain and improved peri-implant bone density. The bioactive plasma gel played a key role in effective sinus membrane elevation and vertical bone augmentation.</p><p><strong>Trial registration number: </strong>This trial was retrospectively registered on ClinicalTrials.gov (ID: NCT06360263) in July 2023.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"158"},"PeriodicalIF":1.8,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjay Chikkarasinakere Jogigowda, Shilpa Padar Shastry, Varusha Sharon Christopher, Karthikeya Patil, Ritu Basavarajappa, Vidya Gowdappa Doddawad, Deepa B V
{"title":"Intra-articular injections in temporomandibular arthralgia: a systematic review.","authors":"Sanjay Chikkarasinakere Jogigowda, Shilpa Padar Shastry, Varusha Sharon Christopher, Karthikeya Patil, Ritu Basavarajappa, Vidya Gowdappa Doddawad, Deepa B V","doi":"10.1007/s10006-025-01448-x","DOIUrl":"10.1007/s10006-025-01448-x","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review evaluates the effectiveness and safety of intra-articular injections for temporomandibular joint (TMJ) arthralgia in adults, comparing various injection types against alternative treatments or placebo.</p><p><strong>Methods: </strong>We conducted a comprehensive literature search across Scopus and Pubmed from January 2015 to December 2024, including randomized controlled trials, prospective comparative clinical trials, and observational studies with control groups. Eligibility criteria required adult patients with clinically diagnosed TMJ arthralgia, various intra-articular injections, and outcome measures including pain reduction and jaw function improvement. The Cochrane Risk of Bias Tool (RoB 2) assessed methodological quality across included studies.</p><p><strong>Results: </strong>The review included seven high-quality studies with sample sizes ranging from 20 to 114 participants across multiple countries. All injection types-corticosteroids, hyaluronic acid, and platelet-rich plasma-demonstrated significant pain reduction and functional improvement within treatment groups. Between-group differences were often not statistically significant in high-quality randomized controlled trials. Specific advantages were noted: sodium hyaluronate may be more effective for reducing joint noises, while corticosteroids showed better short-term pain relief.</p><p><strong>Conclusion: </strong>The evidence supports intra-articular injections as effective treatment options for TMJ arthralgia, though no single intervention consistently outperformed others across all outcomes. Treatment selection should be individualized based on patient presentation and preferences.</p><p><strong>Other: </strong>This review was prospectively registered in PROSPERO (CRD42025632073) and received no external funding.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"155"},"PeriodicalIF":1.8,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145083272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to \"comment on bone-formation-related markers in osteonecrosis of the jaws and their correlation with radiographic findings\".","authors":"Riéli Elis Schulz, Gustavo Davi Rabelo","doi":"10.1007/s10006-025-01460-1","DOIUrl":"https://doi.org/10.1007/s10006-025-01460-1","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"154"},"PeriodicalIF":1.8,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145077195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sahar Mafi, Farzad Rezaei, Arash Bahari Bandari, Navid Bonyadi, Sara Soltani
{"title":"Unveiling the silent emotions: exploring the impact of alexithymia on patient satisfaction after maxillofacial cosmetic surgery.","authors":"Sahar Mafi, Farzad Rezaei, Arash Bahari Bandari, Navid Bonyadi, Sara Soltani","doi":"10.1007/s10006-025-01451-2","DOIUrl":"10.1007/s10006-025-01451-2","url":null,"abstract":"<p><strong>Purpose: </strong>Cosmetic surgery rates have shown a marked increase globally over the past few decades. Patient satisfaction is closely link to individuals' ability to communicate expectations about surgical outcomes. However, people with alexithymia (a condition marked by difficulty in recognizing and expressing emotions) often struggle to articulate their desires or specific concerns about their appearance. This study aimed to evaluate the impact of alexithymia on patient satisfaction following cosmetic surgery, addressing a gap in the existing literature.</p><p><strong>Methods: </strong>This is a cross-sectional observational study incorporated multivariate analysis. The sample was selected by using convenience sampling, based on predefined inclusion and exclusion criteria. Statistical analyses included p-values, independent t-tests, Pearson's correlation coefficients, and multivariate linear regression.</p><p><strong>Results: </strong>Among 304 participants, 29.9% exhibited high levels of alexithymia, 17.4% moderate, and 52.6% low. Regression analysis indicated that higher alexithymia scores were significantly associated with lower patient satisfaction (β = -0.20, 95% CI: -0.33 to -0.07, p = 0.001). While statistically significant, the effect size was small. Other variables such as age, marital status, and history of mental disorders were not significant predictors of satisfaction. The number of cosmetic surgeries showed a borderline positive association with satisfaction (β = 3.42, 95% CI: -0.02 to 6.86, p = 0.05), suggesting a possible relationship that warrants further investigation.</p><p><strong>Conclusion: </strong>Alexithymia may modestly influence satisfaction with cosmetic surgery, highlighting the importance of emotional awareness in patient-provider communication. Our findings provide compelling evidence that individuals with alexithymia are more likely to report lower levels of satisfaction with their cosmetic procedure outcome.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"152"},"PeriodicalIF":1.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kirav Patel, Bryce Thornton, Boyu Ma, Yedeh Ying, Jaime Castro-Nunez
{"title":"Mechanism patterns and age variations in pediatric cranio-maxillofacial trauma: a 5-year analysis of the national trauma data bank.","authors":"Kirav Patel, Bryce Thornton, Boyu Ma, Yedeh Ying, Jaime Castro-Nunez","doi":"10.1007/s10006-025-01450-3","DOIUrl":"10.1007/s10006-025-01450-3","url":null,"abstract":"<p><strong>Purpose: </strong>Pediatric craniomaxillofacial trauma presents unique diagnostic and management challenges due to the anatomical and developmental characteristics of children.</p><p><strong>Methods: </strong>This retrospective study analyzed 795,431 pediatric trauma cases (ages 0-18 years) from the National Trauma Data Bank (2017-2022) to characterize injury patterns and risk factors.</p><p><strong>Results: </strong>Among 119,324 cases (15.0%) involving craniomaxillofacial fractures, incidence increased significantly with age, from 0.93% in infants to 5.59% in adolescents. Motor vehicle collisions were the leading mechanism, doubling fracture risk (odds ratio 2.39, 95% confidence interval 2.19-2.59), while proper restraint use reduced risk by 43% (odds ratio 0.572, 95% confidence interval 0.52-0.62). Falls were the predominant mechanism in younger children, whereas motor vehicle collisions, assault, and firearm-related injuries increased with age. Fracture patterns shifted developmentally: cranial vault fractures dominated in younger children, while cranial base, midface, mandibular, and dental fractures became prevalent in older populations.</p><p><strong>Conclusion: </strong>These findings emphasize the need for age-specific prevention strategies, including improved restraint compliance and targeted injury mitigation programs, to reduce the burden of pediatric facial trauma.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"153"},"PeriodicalIF":1.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12441080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Bone-formation-related markers in osteonecrosis of the jaws and their correlation with radiographic findings\".","authors":"Efsun Somay, Erkan Topkan, Ugur Selek","doi":"10.1007/s10006-025-01456-x","DOIUrl":"https://doi.org/10.1007/s10006-025-01456-x","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"151"},"PeriodicalIF":1.8,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145067561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}