Rezarta Taga Senirli, Deniz Gediz, Yeşim Yüksel, Muhammet Yildiz, Nuray Ensari, N Didem Sonbay Yilmaz, Özer Erdem GüR
{"title":"Incidence of postoperative delirium among patients who underwent head & neck surgery.","authors":"Rezarta Taga Senirli, Deniz Gediz, Yeşim Yüksel, Muhammet Yildiz, Nuray Ensari, N Didem Sonbay Yilmaz, Özer Erdem GüR","doi":"10.1007/s10006-025-01410-x","DOIUrl":"https://doi.org/10.1007/s10006-025-01410-x","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative delirium is a state of confusion and cognitive impairment that can be observed after extensive surgery. This serious complication can lead to longer hospital stays and higher costs. As the global population ages, postoperative delirium has also become a concern for patients undergoing head and neck surgery. In this study, we investigated whether the preoperative recognition of cognitive impairment could help with the prediction of postoperative delirium among patients undergoing head and neck surgery.</p><p><strong>Methods: </strong>We conducted a three-year prospective study in our clinic to analyze 46 patients who underwent surgeries lasting 6 h or longer. Mini-Mental State Examination scores, demographic data, medical history, surgical details and delirium assessments were examined to identify risk factors for postoperative delirium.</p><p><strong>Results: </strong>Our study revealed that 8.7% of the patients developed postoperative delirium. Longer surgery durations, lower serum sodium levels and lower Mini-Mental State Examination scores were risk factors for postoperative delirium.</p><p><strong>Conclusion: </strong>Recognizing cognitive impairment and other potential risk factors during the preoperative period appears to play a critical role in reducing the incidence of postoperative delirium and its associated complications.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"109"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pattern diversity and prevalence of bifid mandibular canal: a CBCT-based cross-sectional study : Evaluation of Bifid Mandibular Canal via CBCT.","authors":"Ali Altındağ, Hilal Yalın, İbrahim Burak Yüksel","doi":"10.1007/s10006-025-01409-4","DOIUrl":"https://doi.org/10.1007/s10006-025-01409-4","url":null,"abstract":"<p><strong>Background: </strong>Accurate determination of the position and configuration of the inferior alveolar canal is crucial for the planning of oral surgical procedures involving the mandible, such as orthognathic surgery, implant placement, impacted tooth extraction, and fracture treatment, to prevent potential complications. This study aims to evaluate the prevalence and types of bifid mandibular canal (BMC) within a subpopulation from Central Anatolia using cone-beam computed tomography (CBCT) images.</p><p><strong>Methods: </strong>The study examined a total of 300 CBCT images, including 118 male and 182 female patients, resulting in the analysis of 600 inferior alveolar canals on both the right and left sides. The anatomy of these canals was assessed according to Naitoh's (2009) classification of BMC into four types: forward canal, dental canal, retromolar canal, and buccolingual canal. Statistical analysis was conducted using SPSS v21.0 (IBM Corp, Armonk, NY, USA). The frequency of BMC was evaluated based on its occurrence on the right and left sides of the mandible, as well as its association with age and gender, using the Chi-square test.</p><p><strong>Results: </strong>Among the 300 patients whose CBCT images were examined, 68 (22.7%) were found to have BMC, with 31 males and 37 females. No significant differences in the frequency of BMC were observed concerning age and gender. The most frequently observed canal type was the dental canal (36.46%).</p><p><strong>Conclusion: </strong>To minimize the risk of complications, it is essential to understand the anatomy of the inferior alveolar canal and its possible anatomical variations before conducting dental procedures and mandibular surgeries. It is recommended to evaluate BMC using CBCT imaging before surgical interventions.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"110"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"- Comments on 'mapping trends in preemptive analgesia related to oral surgery with the use of ibuprofen: a comprehensive quantitative and qualitative analysis of bibliometric parameters' by Cetira et al.","authors":"Yuh-Shan Ho, Nikolaos Christidis","doi":"10.1007/s10006-025-01411-w","DOIUrl":"https://doi.org/10.1007/s10006-025-01411-w","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"108"},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Florian Dudde, Sven Duda, Lawik Revend, Oliver Schuck, Manfred Giese
{"title":"The impact of COVID-19 on facial laceration trends: a comparative analysis of pre- and intra-pandemic data.","authors":"Florian Dudde, Sven Duda, Lawik Revend, Oliver Schuck, Manfred Giese","doi":"10.1007/s10006-025-01403-w","DOIUrl":"https://doi.org/10.1007/s10006-025-01403-w","url":null,"abstract":"<p><strong>Background: </strong>This study explores the impact of the COVID-19 pandemic on the patterns, mechanisms, and clinical management of facial lacerations. By comparing data from pre-pandemic and intra-pandemic periods, it aims to elucidate how COVID 19 influenced maxillofacial trauma care.</p><p><strong>Materials and methods: </strong>A retrospective analysis was conducted on 747 patients treated for facial lacerations at a maxillofacial trauma center. Data were collected for two periods: pre-COVID (February 2019-January 2020) and intra-COVID (February 2020-January 2021). Demographics, injury characteristics, mechanisms, and treatment modalities were analyzed.</p><p><strong>Results: </strong>During the intra-COVID period, the proportion of fall-related facial lacerations nearly doubled (18.6% vs. 39.2%, p < 0.001), while injuries associated with alcohol consumption (43.4% vs. 12.5%, p < 0.001) and interpersonal violence (22.5% vs. 8.3%, p < 0.001) declined markedly. The sex distribution shifted significantly, with female patients comprising a higher proportion of cases during the pandemic (33.3% vs. 45.8%, p < 0.001). Temporal patterns also changed, as morning injuries became substantially more frequent (11.6% vs. 40.0%, p < 0.001). Syncopal events linked to viral infections increased significantly (3.9% vs. 15.0%, p < 0.001). In terms of clinical management, the use of radiographic imaging (69.8% vs. 60.0%, p = 0.005) and tetanus booster administration (42.6% vs. 28.3%, p < 0.001) both declined during the pandemic period.</p><p><strong>Conclusion: </strong>The COVID-19 pandemic significantly altered the epidemiology and clinical management of facial lacerations, as evidenced by shifts in trauma mechanisms, patient demographics, and resource use. These findings highlight the need for adaptive trauma care strategies during public health crises.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"107"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144130033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E M Strabbing, O Engin, M A J Telleman, A P Nagtegaal, E B Wolvius
{"title":"Post-traumatic and iatrogenic silent sinus syndrome: a case series.","authors":"E M Strabbing, O Engin, M A J Telleman, A P Nagtegaal, E B Wolvius","doi":"10.1007/s10006-025-01391-x","DOIUrl":"10.1007/s10006-025-01391-x","url":null,"abstract":"<p><strong>Objectives: </strong>Silent sinus syndrome (SSS) is a rare condition characterized by progressive maxillary sinus collapse, causing enophthalmos and hypoglobus without sinusitis symptoms. Secondary SSS arises from trauma or surgery disrupting mucociliary clearance. This study aims to analyze CT scan features, evaluate the timeline of SSS development, and identify contributing factors.</p><p><strong>Materials and methods: </strong>Patients diagnosed with secondary (post-traumatic or iatrogenic) SSS between January 2015 and January 2024 at the Erasmus Medical Center were reviewed. Characteristics from pre-SSS (T1) and post-SSS (T2) stages, management, and clinical outcomes were recorded. Data on patient demographics, symptoms, orthoptic findings, and the time interval between trauma or surgery and SSS onset were also collected.</p><p><strong>Results: </strong>Nine patients (six males and three females) met the inclusion criteria. The time from trauma or surgery to SSS onset ranged from one to thirty-six months, with a median of three months in the posttraumatic group. All patients presented with unilateral enophthalmos or hypoglobus; eight reported diplopia. Surgical management, including retrograde uncinectomy and orbital reconstruction, restored orbital anatomy and resolved symptoms.</p><p><strong>Conclusion: </strong>Secondary SSS is a rare but significant condition requiring early recognition to prevent severe cosmetic and functional complications.</p><p><strong>Clinical relevance: </strong>Secondary SSS should be considered when patients present with unexplained orbital changes following trauma or surgery. Regular follow-up is recommended, especially in patients with orbital trauma or surgery involving the inferomedial strut. Further studies are necessary to clarify risk factors associated with secondary SSS.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"106"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathas Daniel Paggi Claus, Matheus Spinella Almeida, Hugo José Correia Lopes
{"title":"Anterior oblique osteotomy for mandibular advancements: highlighting a minimally invasive solution.","authors":"Jonathas Daniel Paggi Claus, Matheus Spinella Almeida, Hugo José Correia Lopes","doi":"10.1007/s10006-025-01397-5","DOIUrl":"10.1007/s10006-025-01397-5","url":null,"abstract":"<p><strong>Objective: </strong>Bilateral sagittal split osteotomy (BSSO) is widely used for mandibular advancements but is often associated with complications such as nerve disturbances, limited angle projection, and mandibular notching. This study describes a modification, the anterior oblique osteotomy (AOO), within the minimally invasive orthognathic surgery (MIOS) concept, addressing these challenges.</p><p><strong>Methods: </strong>A single-center retrospective study was conducted involving 30 patients who underwent bimaxillary surgery using AOO. Pre- and postoperative computed tomography scans were analyzed to measure the increase in posterior mandibular height.</p><p><strong>Results: </strong>The mean mandibular advancement was 7.8 mm, with no unfavorable splits or nerve injuries. All patients achieved full recovery of the inferior alveolar nerve by two weeks postoperatively. Significant improvements in posterior mandibular height were observed, increasing from 58.3 mm preoperatively to 67.2 mm postoperatively (p < 0.001). No cases of non-union, malunion, malocclusion, or relapse were reported during follow-up.</p><p><strong>Conclusions: </strong>The AOO technique, when applied within the MIOS framework, presents a viable alternative to traditional BSSO, it offers reduced morbidity and enhanced aesthetic results. Further studies, including control groups, are recommended to confirm the long-term stability of the vertical increase and clinical outcomes.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"105"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Ahmed Hafez El-Sayed, Wafaa Saleh, Samah ElMeadawy, Mohamed A Al-Shahat
{"title":"Impact of timing of soft tissue augmentation on the width of keratinized mucosa around the dental implant.","authors":"Mohamed Ahmed Hafez El-Sayed, Wafaa Saleh, Samah ElMeadawy, Mohamed A Al-Shahat","doi":"10.1007/s10006-025-01401-y","DOIUrl":"10.1007/s10006-025-01401-y","url":null,"abstract":"<p><strong>Purpose: </strong>This study measures the impact of timing of free gingival graft (FGG) in improving aesthetics, function, and long-term stability of dental implants by measuring keratinized mucosa width (KMW), soft tissue thickness (STT), and graft shrinkage after implant treatment.</p><p><strong>Methods: </strong>The current randomized clinical trial included 20 patients with inadequate KMW and requiring placement of dental implant. The participants were randomly distributed into two groups. Group 1 received FGG 2 months before placing the dental implant while group 2 received the FGG at the second stage of implant surgery. The following parameters were evaluated and statistically analyzed at baseline, day 7, as well as 1, 3, 6, and 9 months postoperatively, KMW, STT and shrinkage percentage of the FGG.</p><p><strong>Results: </strong>Twenty patients with ages ranging from 30 to 55 years with reduced KMW were included in the current study. Both groups showed a significant increase in KMW and STT on day7, 1, 3, 6, and 9 months postoperatively while the intergroup comparison showed no significant differences in KWM, STT, and shrinkage percentage between both groups at the same point of time.</p><p><strong>Conclusion: </strong>The two study groups' outcomes demonstrated that the FGG can be placed either before or after dental implants to improve the soft tissue augmentation surrounding the implants. However, the implantologist should take patient preferences and long-term stability into consideration.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"104"},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12092525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Feras AlMofreh AlQahtani, Sam Kuriadom, Michalis Mastrogeorgiou, Abubaker Abualgasim, Hanan Mr Shokier, Shadia A ElSayed
{"title":"Are tongue flaps effective in the closure of palatal fistulas? A systematic review and meta-analysis.","authors":"Feras AlMofreh AlQahtani, Sam Kuriadom, Michalis Mastrogeorgiou, Abubaker Abualgasim, Hanan Mr Shokier, Shadia A ElSayed","doi":"10.1007/s10006-025-01392-w","DOIUrl":"10.1007/s10006-025-01392-w","url":null,"abstract":"<p><strong>Purpose: </strong>Is to Sytematically review the available evidence on the effectiveness of tongue flaps in the Closure of Palatal Fisutlas.</p><p><strong>Methods: </strong>The study protocol was developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols, and it was registered with the International Prospective Register of Systematic Reviews under registration number CRD42023397034.</p><p><strong>Results: </strong>Our search strategy yielded 587 articles. Of these, 150 were duplicate studies, and 437 were screened. Of these studies, 392 studies were excluded based on their titles and abstracts. 45 records were assessed for eligibility in which 29 were excluded as they did not meet the inclusion criteria. Finally, 16 studies met the criteria for inclusion, and they were critically reviewed.</p><p><strong>Conclusion: </strong>This study highlights that tongue flaps, particularly dorsal tongue flaps (DTF) and posterior tongue flaps (PTF), are effective options for palatal fistula closure, demonstrating high success rates and a favorable complication profile. Nonetheless, additional research is necessary to explore the potential of these techniques for closing oroantral fistulas (OAF). Further investigations should employ randomized controlled trials with larger patient cohorts and extended follow-up periods to comprehensively evaluate the efficacy, complication rates, and long-term outcomes of DTF and PTF in OAF treatment.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"103"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark Ooms, Philipp Winnand, Marius Heitzer, Nils Vohl, Marie Sophie Katz, Johannes Bickenbach, Frank Hölzle, Ali Modabber
{"title":"Blood pressure and microvascular free flap perfusion in head and neck reconstruction- a retrospective analysis.","authors":"Mark Ooms, Philipp Winnand, Marius Heitzer, Nils Vohl, Marie Sophie Katz, Johannes Bickenbach, Frank Hölzle, Ali Modabber","doi":"10.1007/s10006-025-01378-8","DOIUrl":"10.1007/s10006-025-01378-8","url":null,"abstract":"<p><strong>Purpose: </strong>The influence of blood pressure on microvascular free flap perfusion is not fully understood and remains an ongoing topic of debate, as flap perfusion is both a prerequisite for flap viability and a parameter frequently used for postoperative flap monitoring. The aim of this study was to investigate the influence of blood pressure on microvascular free flap perfusion.</p><p><strong>Methods: </strong>Perfusion measurement data obtained with the Oxygen-2-see (O2C) analysis system intraoperatively and postoperatively in 244 patients who underwent microvascular reconstruction of the head and neck region with a fasciocutaneous free flap (FFF) or perforator free flap (PFF) between 2011 and 2020 were analyzed retrospectively. Blood pressure values (i.e., systolic (SBP), diastolic (DBP), and mean arterial blood pressure (MBP)) and perfusion parameters (i.e., flap blood flow, hemoglobin concentration, and hemoglobin oxygen saturation) were evaluated to reveal potential associations.</p><p><strong>Results: </strong>Postoperative flap blood flow was associated with SBP, DBP, and MBP in PFFs (r = 0.245, p = 0.006; r = 0.239, p = 0.008; r = 0.295, p < 0.001, respectively). These associations also persisted in multivariable analysis (p = 0.036; p = 0.024; p = 0.004, respectively). Postoperative hemoglobin oxygen saturation was associated with SBP and MBP in PFFs (r = 0.253, p = 0.005; r = 0.189, p = 0.036, respectively). The association with SBP also persisted in multivariable analysis (p = 0.005).</p><p><strong>Conclusion: </strong>Microvascular free flap perfusion in PFFs, specifically postoperative flap blood flow and hemoglobin oxygen saturation, is influenced by blood pressure. This suggests that blood pressure might be an adjustable variable for the control of flap perfusion and should be considered as a confounding variable for flap monitoring based on flap perfusion in PFFs.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"85"},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144130030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Articaine use does not routinely eliminate the need for palatal injections for primary maxillary molar extractions: a randomized cross-over clinical trial.","authors":"Zahra Bahrololoomi, Nahid Maghsoudi","doi":"10.1007/s10006-021-01021-2","DOIUrl":"https://doi.org/10.1007/s10006-021-01021-2","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to compare single buccal infiltration of 4% articaine versus routine buccal and palatal injections of 2% lidocaine during bilateral extraction of maxillary primary molars.</p><p><strong>Methods: </strong>Thirty healthy children aged 6-9 years old requiring bilateral extraction of maxillary primary molars were enrolled into the trial. Randomization was performed in two steps. Routine buccal and palatal infiltrations were administered using 2% lidocaine in the control side. Four percent articaine was used for single buccal infiltration in the intervention side. WBFP scale (Wong-Baker FACES Pain scale) was employed for subjective assessment of pain. For objective evaluation of pain, FLACC scale (Face, Legs, Activity, Cry, Consolability) and physiological parameters of blood pressure and pulse rate were recorded.</p><p><strong>Results: </strong>Analyses did not show any significant differences in blood pressure, pulse rate, and FLACC scale between groups (P value > 0.05). However, statistically lower WBFP scores were observed in articaine group as compared to lidocaine group (P value < 0.05); the difference was less than one unit which is not clinically considerable.</p><p><strong>Conclusion: </strong>Single buccal infiltration of 4% articaine can be administered as an alternative for conventional infiltration of 2% lidocaine to avoid fear or uncooperative behavior of the child patient. However, the assessment of palatal tissue anesthesia is quite necessary before the procedure is initiated. In case of failure in achieving palatal anesthesia, a palatal injection should be given.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"603-611"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39683533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}