{"title":"Enhancing submandibular gland resection: A retrospective study on the efficacy of the ORBEYE 3D exoscope.","authors":"Masao Yagi, Mizuki Morita, Tomofumi Sakagami, Minaki Shimizu, Toshiki Utsunomiya, Kensuke Suzuki, Takuo Fujisawa, Hiroshi Iwai","doi":"10.1007/s10006-025-01446-z","DOIUrl":"10.1007/s10006-025-01446-z","url":null,"abstract":"<p><strong>Purpose: </strong>For submandibular gland resection, conventional surgery with the naked eye remains the standard. With its excellent automatic focus and high magnification, the ORBEYE 3D exoscope enables precise submandibular gland resection with less stress. Therefore, we aimed to examine the usefulness of the exoscope in submandibular gland resection.</p><p><strong>Methods: </strong>This retrospective study involved 12 patients who underwent submandibular gland resection with the ORBEYE exoscope at the Department of Head and Neck Surgery and Otorhinolaryngology at Kansai Medical University from April 2021 to March 2024. Surgical outcomes were retrospectively reviewed.</p><p><strong>Results: </strong>The mean age of the patients (six women and six men) was 58.5 (23-83) years. The final histopathology showed pleomorphic adenoma in eight patients, non-sebaceous-type lymphadenoma and carcinoma ex pleomorphic adenoma in one patient each, and sialolithiasis with chronic inflammation in two patients. We performed facial artery and vein sparing in all patients except one, in whom level I neck dissection, including submandibular gland excision, was performed. We identified the marginal mandibular branches of the facial, hypoglossal, and lingual nerves, as well as the submandibular duct in all patients. There were no postoperative complications in any of the patients. The mean operative time was 104 (80-129) min. The mean blood volume lost was 20 (5-43) mL.</p><p><strong>Conclusion: </strong>Using the ORBEYE exoscope in submandibular gland resection will contribute to preserving the mandibular marginal branch of the facial and lingual nerves and facial and artery veins, and visualizing the submandibular ducts, which are important structures surrounding the submandibular gland.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"149"},"PeriodicalIF":1.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kan Wang, Jiajia Zheng, Jinghua He, Yuan Fu, Xiaoming Lyu
{"title":"External root resorption of second molars caused by impacted third molars: CBCT characteristics.","authors":"Kan Wang, Jiajia Zheng, Jinghua He, Yuan Fu, Xiaoming Lyu","doi":"10.1007/s10006-025-01436-1","DOIUrl":"10.1007/s10006-025-01436-1","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to describe the cone-beam computed tomography (CBCT) characteristics of external root resorption (ERR) in second molars associated with impacted third molars.</p><p><strong>Methods: </strong>This study analyzed 69 s molars diagnosed with ERR caused by impacted third molars in 52 patients (age range: 22-59 years; mean age = 31.2 ± 7.1 years) to identify key factors influencing the severity and occurrence of ERR. CBCT was used to assess the relationship between impacted third molar characteristics (position, angulation, proximity) and the extent of root resorption in adjacent second molars.</p><p><strong>Results: </strong>ERR most commonly affected mandibular second molars (37 teeth: 60.0%, 47 teeth: 40.6%). Resorption extended to the pulp chamber in 47.9% of cases, while 40.6% was limited to superficial/middle dentin. 24.6% of the ERR sites were in communication with the oral cavity. 87% of impacted third molars were low-level, and 38% were completely bone-impacted. 26% had an angulation > 90° relative to the affected tooth. Complete bone impaction significantly correlated with ERR extending to the pulp chamber (65%, p < 0.05). ERR communicating with the oral cavity significantly increased pain on percussion. Younger patients were more likely to have ERR extending to the pulp chamber.</p><p><strong>Conclusions: </strong>Low-level and complete bone impactions of impacted third molars significantly contribute to the development of ERR in adjacent second molars. Communication between the ERR site and the oral cavity is associated with a high risk of infection.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"150"},"PeriodicalIF":1.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Delavaquerie-Lesnes, Esteban Brenet, Stéphane Derruau, Thomas Clement, Cédric Mauprivez
{"title":"MR imaging evaluation of accidental third molar displacement into parapharyngeal space: a case report.","authors":"Sarah Delavaquerie-Lesnes, Esteban Brenet, Stéphane Derruau, Thomas Clement, Cédric Mauprivez","doi":"10.1007/s10006-025-01444-1","DOIUrl":"https://doi.org/10.1007/s10006-025-01444-1","url":null,"abstract":"<p><p>Accidental displacement of impacted and non-erupted upper third molars into the maxillary sinus, buccal space, infratemporal fossa, and lateral pharyngeal space is uncommon. Herein, we present an unusual case of parapharyngeal cellulitis secondary to iatrogenic displacement of the right third molar. Clinical history, physical examination, and imaging assessment are essential in the evaluation of teeth projected into adjacent anatomic spaces. Panoramic radiography, the first-line imaging modality used to help screen and visualize the abnormal position of the tooth, is not sufficient. Additional investigation is required to depict and localize the displaced tooth, assess potential complications, and guide removal. We suggest preoperative MRI to minimize perioperative risks, with a special focus on the most adjacent vulnerable structures, and intraoperative C-arm fluoroscopy imaging to contribute to safe minimally invasive surgery.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"148"},"PeriodicalIF":1.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144986733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eman Azmy, Rehab R A El-Zehary, Fatma M M Ibrahim, Mona Denewar
{"title":"The synergetic potential of gold nanoparticles and bone marrow stem cells in regeneration of tongue defects (An experimental study on Rats).","authors":"Eman Azmy, Rehab R A El-Zehary, Fatma M M Ibrahim, Mona Denewar","doi":"10.1007/s10006-025-01433-4","DOIUrl":"https://doi.org/10.1007/s10006-025-01433-4","url":null,"abstract":"<p><strong>Purpose: </strong>The tongue plays a vital role in physiological functions where tissue loss impairs the patient's life, so regenerative approaches are crucial. This study was performed to explore the synergetic possibility of gold nanoparticles (AuNPs) and bone marrow stem cells (BMSCs) in tongue defect regeneration.</p><p><strong>Methods: </strong>Rats were subjected to surgical defects on the tongue's dorsal surface and divided into four groups: Group I (control): received no treatment, Group II (AuNPs): received 0.1 ml AuNPs solution (50 nm diameter) 1 mm sub-epithelial, Group III (BMSCs): received 0.1 ml BMSCs (3.5 × 105 cells/cm2), and Group IV (BMSCs/AuNPs) received 0.1 ml BMSCs (3.5 × 105 cells/cm2) previously cultured with 6 µg/ml AuNPs. Circumferential injections were made around the defect. Samples were collected and prepared for histological and immunohistochemical staining four and seven days after treatment, and then histomorphometric and statistical analyses were performed.</p><p><strong>Results: </strong>The BMSCs/AuNPs group revealed better histological regeneration, including consistent epithelial stratification with a thick keratin layer, a regularly arranged basal cell layer, more vascularity, and well-arranged muscle bundles in connective tissue with fewer inflammatory cells than other groups. Regarding immunohistochemical. results, the BMSCs/AuNPs group demonstrated a significant increase in PCNA and S100 expression in both time intervals in comparison with other groups.</p><p><strong>Conclusions: </strong>Wound healing after AuNPs in conjugation with BMSCs emphasized their synergetic effect on BMSCs. Attained. results extend to applied nanotechnology and regenerative medicine, supporting the application of AuNPs in wound healing fields.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"147"},"PeriodicalIF":1.8,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144986785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interventions to minimize periodontal defect distal to second molar after mandibular third molar surgery: an overview of systematic reviews.","authors":"Ioulianos Apessos, Christodoulos Dovas, Spyridon Mantalenakis, Theodoros Lillis, Georgios Antonoglou","doi":"10.1007/s10006-025-01432-5","DOIUrl":"https://doi.org/10.1007/s10006-025-01432-5","url":null,"abstract":"<p><strong>Purpose: </strong>This overview summarized different interventions that were performed for minimizing periodontal defects distal to the mandibular second molar and improve hard and soft tissue healing after third molar surgery.</p><p><strong>Methods: </strong>Literature search was conducted in the following 9 databases: Medline (via Pubmed), ScienceDirect, Scopus, Virtual Health Library, Wiley Online Library, Web of Science, ProQuest Dissertations and Theses Global and Google Scholar. Systematic reviews with or without meta-analysis investigating the effect of different interventions on soft and hard tissue healing after third molar surgery were considered. Methodological quality of included reviews was assessed with AMSTAR-2 tool. The degree of overlapping of index publications in the eligible reviews was presented and calculated with the GROOVE tool.</p><p><strong>Results: </strong>Thirty-three reviews were included, collectively encompassing 191 distinct primary studies that evaluated flap design, extraction socket management, and postsurgical care. Quantitative data retrieved from the methodologically rigorous MAs revealed that the application of autologous platelet concentrates (APCs) is the best choice to improve soft tissue healing [MD = 1.01; 95% CI (0.77, 1.24), 7 days follow-up] and bone mineral density [SMD = 2.34; 95% CI (0.18,4.51), 4 months follow-up] and alleviate pain [SMD= -0.86; 95% CI (-1.26, -0.46), 3 days follow-up], trismus [SMD= -0.26; 95% CI (-0.48, -0.03), 7 days follow-up], alveolar osteitis [RR = 0.43; 95% CI (0.28, 0.65)] and swelling [MD= -1.66; 95% CI (-2.43, -0.90), 3 days follow-up]. Ridge preservation is the most effective intervention in improving pocket probing depth [MD= -1.42; 95% CI (-2.01, -0.83), 6-72 months follow-up], clinical attachment level [MD = 1.98; 95% CI (1.44, 2.52), 4.5-72months follow-up] and alveolar bone height [MD = 1.21; 95% CI (0.21, 2.21), 6-12 months follow-up] distal to mandibular second molar.</p><p><strong>Conclusion: </strong>Minimizing tissue trauma is key in surgical extractions. Our overview found that triangular flaps reduce PPD, while envelope flaps lower postoperative pain. APCs improved healing and reduced adverse events, and HyA mainly alleviated pain. All regenerative techniques enhanced periodontal outcomes, though high heterogeneity and variable study quality urge cautious interpretation.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"146"},"PeriodicalIF":1.8,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144986770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addressing key limitations in the occurrence and outcomes of retrobulbar haematoma in 2149 orbital fracture patients.","authors":"Muhammad Ahsan, Minahil Laraib Asif","doi":"10.1007/s10006-025-01443-2","DOIUrl":"10.1007/s10006-025-01443-2","url":null,"abstract":"<p><p>We commend Narjus-Sterba et al. for their significant contribution in reporting the prevalence and consequences of retrobulbar hematoma (RBH) in a large cohort of patients with orbital fractures. Their work draws attention to a vision-risking but under-emphasized complication and underscores the utility of CT scan and pupillary reflex as early indicators of visual prognosis. Nevertheless, several aspects warrant further discussion. Of particular note is the failure to stratify outcomes by exact time-to-treatment intervals, lack of long-term visual follow-up in a considerable number of patients, and heterogeneity in treatment modalities weaken the impact of outcome interpretation. Additionally, inadequate granularity of fracture characterization and absence of a uniform treatment protocol might confine the study's significance. We recommend that future studies incorporate subgroup analyses on a detailed basis according to intervention timing, CT-based fracture severity scores, and evidence-based treatment pathways to facilitate standardized management. Prospective, multicenter trials could also more effectively control for confounding variables like comorbidities and coagulopathies. Eliminating these limitations will improve the validity and clinical utility of future research in the management of RBH complicated by orbital trauma.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"145"},"PeriodicalIF":1.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144885020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moataz Bahaa, Abdelrahman Mohamed Fahmy Abdelhameed Azab, Hisham Mohamed Mahmoud Ali El Sheikh, Bassam A Abulnoor, Amr Amin Ghanem, Sherif Shafik El Bahnasy, Karim Mohamed AbdelMohsen
{"title":"Does ultrasound guidance during arthrocentesis in women with disc displacement without reduction reduce procedure time and improve outcomes? A randomized clinical trial.","authors":"Moataz Bahaa, Abdelrahman Mohamed Fahmy Abdelhameed Azab, Hisham Mohamed Mahmoud Ali El Sheikh, Bassam A Abulnoor, Amr Amin Ghanem, Sherif Shafik El Bahnasy, Karim Mohamed AbdelMohsen","doi":"10.1007/s10006-025-01442-3","DOIUrl":"10.1007/s10006-025-01442-3","url":null,"abstract":"<p><strong>Introduction: </strong>The goal of using ultrasound-guided (USG) arthrocentesis is to reduce number of needle insertion attempts, which is hypothesized to reduce procedure time, postoperative pain, and consequently, limitation in range of motion.</p><p><strong>Purpose: </strong>The objective of this study was to compare the therapeutic and operative efficiency of USG Single-Puncture Arthrocentesis (SPA) Type 2 and SPA Type 2 arthrocentesis without ultrasound guidance in the treatment of temporomandibular joint (TMJ) internal derangement (ID) \"disc displacement without reduction (DDWOR).\"</p><p><strong>Materials and methods: </strong>A double-blinded prospective randomized clinical trial (RCT) was conducted from December 2022 to December 2023 at Ain Shams University Hospital. It enrolled females with a mean age of 27.00 ± 3.70 years with DDWOR and failed conservative treatment, excluding those with malocclusion, parafunctional habits, systemic diseases, psychological disorders or requiring special needs. In the study, 40 female patients with DDWOR were randomly divided into a control group (SPA Type 2 arthrocentesis) and an intervention group (USG SPA Type 2 arthrocentesis). Patients were assessed for needle insertion attempts as the primary outcome. procedure time, pain measured using visual analogue scale (VAS), and maximum mouth opening (MMO) were also assessed. Follow-up was conducted at 4, 8, and 12 weeks. Patients with differences in age and gender, malocclusion, parafunctional habits, systemic diseases, or psychological disorders were excluded.</p><p><strong>Results: </strong>The intervention group had fewer needle insertion attempts (1.6 vs. 2.9) and shorter procedure time (11.75 vs. 16 min, p < 0.001). Pain scores (p = 0.846) and maximum mouth opening (p = 0.341) showed no statistically significant differences after 12 weeks. Data were summarized as mean, SD, median, and IQR, with normality assessed by examining the distribution and using the Shapiro-Wilk test. Non-parametric variables were compared using the Mann-Whitney U test. Linear mixed models were assessed via residual plots, Q-Q plots, Shapiro-Wilk, Breusch-Pagan, and VIF tests. Fixed effects were analyzed with ANOVA or Wald Chi-Square tests, followed by Tukey's post-hoc comparisons. Analyses were conducted using R 4.5.0.</p><p><strong>Conclusions: </strong>USG SPA Type 2 arthrocentesis demonstrated improved procedural efficiency, evidenced by fewer needle insertion attempts and shorter procedure duration. However, it did not result in statistically significant differences in therapeutic outcomes, including pain reduction or maximum mouth opening (MMO). Further research is warranted to determine whether ultrasound guidance provides additional clinical benefits beyond technical facilitation.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"144"},"PeriodicalIF":1.8,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Othoniel Hugo Aragon-Martinez, Eduardo Gómez-Sánchez, Ronell Bologna-Molina, Nelly Molina-Frechero, Sandra López-Verdín, Nicolás Serafín-Higuera, Juan Manuel Guzmán-Flores, Maikel Hermida-Rojas, Mario Alberto Isiordia-Espinoza
{"title":"Author's Reply to the Comment on \"Pain control and adverse effects of parecoxib after wisdom teeth surgery: a quantitative systematic review\".","authors":"Othoniel Hugo Aragon-Martinez, Eduardo Gómez-Sánchez, Ronell Bologna-Molina, Nelly Molina-Frechero, Sandra López-Verdín, Nicolás Serafín-Higuera, Juan Manuel Guzmán-Flores, Maikel Hermida-Rojas, Mario Alberto Isiordia-Espinoza","doi":"10.1007/s10006-025-01441-4","DOIUrl":"10.1007/s10006-025-01441-4","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"143"},"PeriodicalIF":1.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leela Lakshmi Sai Srinivas Parasa, Bhaskar Kambhampati, Ranjana Sah
{"title":"Comment on \"Pain control and adverse effects of parecoxib after wisdom teeth surgery: a quantitative systematic review\".","authors":"Leela Lakshmi Sai Srinivas Parasa, Bhaskar Kambhampati, Ranjana Sah","doi":"10.1007/s10006-025-01434-3","DOIUrl":"10.1007/s10006-025-01434-3","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"142"},"PeriodicalIF":1.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bone-formation-related markers in osteonecrosis of the jaws and their correlation with radiographic findings.","authors":"Riéli Elis Schulz, Sandro Wopereis, Juliana Lucena Schussel, Laurindo Moacir Sassi, Aira Maria Bonfim Santos, Liliane Janete Grando, Rogério Oliveira Gondak, Gustavo Davi Rabelo","doi":"10.1007/s10006-025-01439-y","DOIUrl":"https://doi.org/10.1007/s10006-025-01439-y","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate serum levels of the bone-formation-related markers sclerostin and alkaline phosphatase (ALP) in patients with medication-related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis (ORN), and to identify a correlation with radiographic findings.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with osteonecrosis patients [MRONJ (n = 11); ORN (n = 21)] compared with individuals without osteometabolic diseases (control group, CG n = 27). Serum levels of sclerostin (pg/ml) and ALP (U/L) were evaluated. Gray-level pixel intensity (mean-Mgv and standard deviation-SDgv), fractal dimension (FD), and lacunarity (Lac) in the necrotic site (N), at the perinecrotic bone (PB), and in the non-lesional-bone site (CB) were assessed.</p><p><strong>Results: </strong>Higher sclerostin levels were observed in ORN (90, p = 0.04) and MRONJ (133, p < 0.01) vs. CG (45). ALP differed (p < 0.01) between MRONJ (60.2) and CG (79.3). All radiographic parameters revealed significant differences among the 3 sites (p < 0.05). A multivariate analysis showed an association of sclerostin with Mgv at N (p = 0.002) and Lac (p < 0.004) at CB, and an association of ALP with Mgv at N (p < 0.01), SDgv at PB (p < 0.01), and with sclerostin (p < 0.01).</p><p><strong>Conclusions: </strong>Serum sclerostin levels were higher in patients with osteonecrosis. ALP levels were lower in MRONJ patients than in CG. Both proteins were associated with each other and with radiographic findings.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":"29 1","pages":"140"},"PeriodicalIF":1.8,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144819066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}