Oral and maxillofacial surgery最新文献

{"title":"Proinflammatory cytokines levels in patients with temporomandibular joint disorder undergoing arthroscopy.","authors":"Boaz Frenkel,&nbsp;Fadi Abu Shqara,&nbsp;Adi Rachmiel","doi":"10.1007/s10006-021-01014-1","DOIUrl":"https://doi.org/10.1007/s10006-021-01014-1","url":null,"abstract":"<p><strong>Purpose: </strong>Biomarkers represent objective indicators of normal processes, pathology, or responses to therapeutic intervention. The purpose of this study is to evaluate the levels of proinflammatory cytokines in synovial fluid of the temporomandibular joint (TMJ) and to investigate whether there is a correlation between elevated levels and disease progression.</p><p><strong>Materials and methods: </strong>This is a prospective study that included patients who were diagnosed with internal derangement according to magnetic resonance imaging and were classified according to Wilkes's classifications. After failing to improve with conservative treatment, they were referred for TMJ arthroscopy. During arthroscopy, synovial fluid was collected for biomarker analyses that included the investigation of levels of proinflammatory cytokines: tumor necrosis factor (TNF-α), interleukin 6 (IL-6), and vascular endothelial growth factor (VEGF). The Mann-Whitney U test was used for differences between subgroups for TNF-α, IL-6, and VEGF.</p><p><strong>Results: </strong>During the study period, 22 patients presented with a TMJ disorder and met the criteria of the study. There was a statistically significant correlation between the levels of VEGF, TNF-a, and osteoarthritis (P < 0.05). There was also a statistically significant correlation between TNF-a levels and a higher degree of chondromalacia (P = 0.019).</p><p><strong>Conclusion: </strong>An increase in inflammatory cytokines coupled with chondromalacia propose a more aggressive degenerative disease.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"575-580"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39664048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of the mandibular plane and magnitude of the movement in sagittal split ramus osteotomy: an in vitro study.","authors":"Gleysson Matias de Assis,&nbsp;Victor Diniz Borborema Dos Santos,&nbsp;Salomão Israel Monteiro Lourenço Queiroz,&nbsp;Adriano Rocha Germano","doi":"10.1007/s10006-021-01024-z","DOIUrl":"https://doi.org/10.1007/s10006-021-01024-z","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate fixation resistance in mandibular sagittal split ramus osteotomy in standardized polyurethane hemimandibles with two types of advancement (6 and 12 mm), with or without mandibular plane rotation, using a 2.0-mm plate/screw system.</p><p><strong>Methods: </strong>Seven groups were evaluated using a vertical compressive load in the first molar region, and the applied force in Newtons was recorded in 1 mm, 5 mm, and 10 mm displacements, as well as the maximum force.</p><p><strong>Results: </strong>There was a statistical intergroup difference and it was observed that increasing the advancement decreased fixation resistance with a single plate, and inserting an additional plate significantly increased osteosynthesis resistance.</p><p><strong>Conclusion: </strong>In the 12 mm advancements, clockwise rotation proved to be more resistant when fixed with only one plate. By contrast, counterclockwise rotation was significantly more resistant in stabilizing the mandibular sagittal ramus osteotomy when two plates were used.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"625-631"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39798992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autologous platelet concentrates in extraction sockets for the prevention of osteoradionecrosis: a systematic review of controlled clinical trials.","authors":"Rafael Verardi Serrano,&nbsp;Thiago Pallin Gomes,&nbsp;Felipe Medeiros da Silva,&nbsp;Leandro Chambrone,&nbsp;Marcia Martins Marques,&nbsp;Luiz Felipe Palma","doi":"10.1007/s10006-021-01030-1","DOIUrl":"https://doi.org/10.1007/s10006-021-01030-1","url":null,"abstract":"<p><p>This systematic review aimed to assess whether the use of autologous platelet concentrates immediately after tooth extraction would prevent ORN in patients treated with radiotherapy (RT) for head and neck cancer (HNC). MEDLINE, Embase, Ovid, Scopus, Web of Science, CENTRAL Cochrane, and OpenGrey databases were searched (up to, and including, June 2021) by two independent reviewers to identify studies, followed by further manual search. As inclusion and exclusion criteria for the studies, only controlled clinical trials (randomized or not) were considered. The risk of bias of each included study was assessed using the Cochrane Risk of Bias Tool. Of the 129 potentially eligible studies, only 2 were included, both randomized controlled clinical trials; however, one used platelet-rich plasma and another leukocyte- and platelet-rich fibrin. Overall, both autologous platelet concentrates had no effect on the outcome assessed. The use of autologous platelet concentrates seems not to be beneficial for ORN prevention following tooth extractions in HNC patients treated with RT; however, according to the available evidence, a reliable statement cannot be made.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"555-561"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39835032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: The hierarchy of different treatments for myogenous temporomandibular disorders: a systematic review and network meta‑analysis of randomized clinical trials.","authors":"Essam Ahmed Al-Moraissi,&nbsp;Paulo César Rodrigues Conti,&nbsp;Abdulmalik Alyahya,&nbsp;Khaled Alkebsi,&nbsp;Ahmed Elsharkawy,&nbsp;Nikolaos Christidis","doi":"10.1007/s10006-021-01019-w","DOIUrl":"https://doi.org/10.1007/s10006-021-01019-w","url":null,"abstract":"","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"679"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39697601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The hierarchy of different treatments for myogenous temporomandibular disorders: a systematic review and network meta-analysis of randomized clinical trials.","authors":"Essam Ahmed Al-Moraissi,&nbsp;Paulo César Rodrigues Conti,&nbsp;Abdulmalik Alyahya,&nbsp;Khaled Alkebsi,&nbsp;Ahmed Elsharkawy,&nbsp;Nikolaos Christidis","doi":"10.1007/s10006-021-01009-y","DOIUrl":"https://doi.org/10.1007/s10006-021-01009-y","url":null,"abstract":"<p><p>The best treatment modality for the management of painful temporomandibular disorders of muscular origin (M-TMD) with predictable outcomes based on solid evidence is still not well defined. Thus, the aim of this network meta-analysis (NMA) was to identify the best treatment for adult patients with M-TMD. An electronic search was undertaken from the inception of each database to August 2018, to identify randomized clinical trials (RCTs), which are comparing two or more of the following treatment modalities in patients with M-TMD: counseling therapy; occlusal appliances; manual therapy; laser therapy; dry needling; intramuscular injection of local anesthesia (LA) or botulinum toxin-A (BTX-A); muscle relaxants; hypnosis/relaxation therapy; oxidative ozone therapy; and placebo or no treatment. Primary outcome variables were the reduction of pain and mechanical sensitivity. The secondary outcome was the maximal mouth opening (MMO). The quality of evidence was rated according to Cochrane's tool for assessing risk of bias. Standardized mean difference was used to analyze via frequentist network meta-analysis (NMA), using STATA software. 52 RCTs were included in this NMA. At the most follow up moments, manual therapy, counseling therapy, occlusal splints therapy, and needling using BTX-A or LA as well as dry needling significantly decreased post-treatment pain intensity in M-TMDs, when compared to placebo.  At short term (≤5 months), the four highest-ranked treatments for post-treatment pain reduction were manual therapy (83.5%, low quality evidence), ozone therapy (75.7%, very low quality evidence),counseling  therapy (71.2%, moderate quality), and occlusal appliances  (71.7%,moderate quality evidence). When intermediate term (≥6 months)was considered, BTX-A (85.8%, very low quality evidence) , counseling therapy(80%, low quality evidence), occlusal appliances  (62.8%, low quality evidence) and hypnosis (50.6%, very low quality evidence) were the four highest-ranked treatments.  This NMA reveals that manual therapy can be considered the most effective treatment for M-TMD, followed by counseling treatment, intramuscular injection of LA, and occlusal appliances  . However, considering the limitations of the studies included, and the scarce of strong evidence, the present findings should be interpreted cautiously.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"519-533"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39539201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The contralateral based Cervico-pectoral rotation flap for large neck defects.","authors":"Naveena A N Kumar,&nbsp;Punit Singh Dikhit,&nbsp;Nawaz Usman,&nbsp;Keshava Rajan,&nbsp;Preethi S Shetty","doi":"10.1007/s10006-021-01022-1","DOIUrl":"https://doi.org/10.1007/s10006-021-01022-1","url":null,"abstract":"<p><strong>Purpose: </strong>We here describe our technique of contralateral based cervico-pectoral (CCP) flap for the reconstruction of large neck defect following resection of primary tumour or recurrence particularly due to the lymph node mass.</p><p><strong>Methods: </strong>The study included the patients who underwent major head and neck surgical ablative procedures followed by CCP flap reconstruction between July 2020 and November 2020. Patients were kept on rigorous regular follow-up to evaluate for flap related complications like flap necrosis, flap dehiscence and oro-cutaneous fistula. Among the 5 patients included and presented in the series, 2 patients were salvage cases post adjuvant treatment.</p><p><strong>Results: </strong>Five patients who have undergone head and neck reconstruction using CCP flap were included. No major flap related complications occurred in post-operative period.</p><p><strong>Conclusion: </strong>The CCP flap is simple to perform and reproducible and can be added to the armamentarium for the reconstruction of large upper neck defect following resection of primary tumour or recurrence involving the cervical skin in resource limited setting and in contraindication for microvascular reconstruction. Proper planning, meticulous dissection and adequate release or rotation and tension free closure would provide best outcomes.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"581-586"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39730954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of low-speed drilling without irrigation on osseointegration: an experimental study in dogs.","authors":"Shigeo Fujiwara,&nbsp;Daniele Botticelli,&nbsp;Naoki Kaneko,&nbsp;Joaquin Urbizo Velez,&nbsp;Margherita Tumedei,&nbsp;Franco Bengazi","doi":"10.1007/s10006-021-01023-0","DOIUrl":"https://doi.org/10.1007/s10006-021-01023-0","url":null,"abstract":"<p><strong>Objective: </strong>To study the early phases of osseointegration at implants installed in sites prepared with either high rotational speed with irrigation or low rotational speed without irrigation.</p><p><strong>Material and methods: </strong>After 3 months from tooth extraction, two implants were installed in one side of the mandible of twelve dogs. The osteotomies were prepared either at 60 rpm without irrigation or at 750 rpm with refrigeration. Biopsies were obtained after 4 and 8 weeks of healing, six animals each period for histological analyses.</p><p><strong>Results: </strong>After 4 weeks of healing, new bone percentage in contact with the implant surface (BIC%) was 46.6 ± 7.3% and 43.1 ± 6.8% at the low- and high-speed sites, respectively (p = 0.345). After 8 weeks of healing, the fractions increased to 60.0 ± 11.1% and 60.2 ± 6.2%, respectively (p = 0.753).</p><p><strong>Conclusions: </strong>Implants installed in sites prepared using either low-rotational drilling without irrigation or high speed with irrigation presented similar amounts of osseointegration.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"595-601"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39773437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avoidance of milk and dairy products after oral surgery-is such a recommendation still valid? A cross-sectional study among German and international oral and maxillofacial surgeons and dental practitioners with review of the literature.","authors":"Schiwa Seyedi Moghaddam,&nbsp;Andreas Neff","doi":"10.1007/s10006-021-01017-y","DOIUrl":"https://doi.org/10.1007/s10006-021-01017-y","url":null,"abstract":"<p><strong>Purpose: </strong>For prevention of wound-healing complications, patients in German-speaking countries are traditionally advised to avoid consumption of milk and dairy products after oral surgery. In the absence of national and international guidelines, this study investigates scientific evidence and compares international practice, frequency scale, and rationale behind such recommendation.</p><p><strong>Methods: </strong>Comparison of a German cross-sectional mono-center-questionnaire pilot study and a survey among international oral and maxillofacial surgeons (OMFS), specialized oral surgeons and general dentists, evaluating international practice regarding post-operative dietary and nutrition recommendations. Our literature review further assessed scientific evidence for relevant effects of probiotics, prebiotics, and/or synbiotics.</p><p><strong>Results: </strong>Among German study participants, 56% (n = 64/114) advise patients to avoid milk and dairy products, with 42% of OMFS (n = 38) and 65% (n = 76) of the general dentists recommending abstention (p = .027). In striking contrast, such recommendation could not be identified in our international survey (n = 143) (t test, p < .001) nor in the literature. There were significant differences between German and international study participants regarding the rationale for dietary recommendations, with dental schools and literature most frequently indicated as sources (Fisher's exact test, p < .001).</p><p><strong>Conclusion: </strong>The hypothesis of a harmful effect of the consumption of milk and dairy products after dentoalveolar surgery could not be supported by evidence. The recommendation to avoid dairy products post-surgery was identified as a specific phenomenon practiced almost exclusively in German-speaking countries. Corresponding recommendations, most probably based on a now irrelevant risk of contracting tuberculosis from milk products, can at present no longer be substantiated.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"563-573"},"PeriodicalIF":1.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9643201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39558162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of three-dimensional soft tissue profile prediction in orthognathic surgery.","authors":"Amanda Lury Yamashita,&nbsp;Liogi Iwaki Filho,&nbsp;Flávio Wellington da Silva Ferraz,&nbsp;Adilson Luiz Ramos,&nbsp;Isolde Terezinha Dos Santos Previdelli,&nbsp;Omar Cléo Neves Pereira,&nbsp;Elen de Souza Tolentino,&nbsp;Mariliani Chicarelli,&nbsp;Lilian Cristina Vessoni Iwaki","doi":"10.1007/s10006-021-00988-2","DOIUrl":"https://doi.org/10.1007/s10006-021-00988-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the accuracy of three-dimensional (3D) soft tissue prediction in bimaxillary orthognathic surgery.</p><p><strong>Methods: </strong>Cone-beam computed tomographs of 88 patients with class II (n = 46) and class III (n = 42) malocclusions, who underwent bimaxillary orthognathic surgery, were included in this retrospective study. 3D soft tissue prediction and postoperative outcome were compared by using ten landmarks of facial soft tissues. Patients' sex and age were also assessed. Results were analyzed using a mixed model methodology (p < 0.05).</p><p><strong>Results: </strong>The success criterion adopted was a mean discrepancy of < 2 mm. Most mandibular landmarks indicated a tendency for underprediction with a downward direction in class II patients, with some values > 2 mm. In class III, there was overprediction with a downward direction for the mandibular landmarks, with values < 2 mm. More accurate results were found in female and older patients.</p><p><strong>Conclusions: </strong>3D surgical planning showed clinically acceptable results for predicting soft tissues in patients undergoing bimaxillary orthognathic surgery, with more accurate results for class III patients. Although some differences were found when age and sex were interacted, a consistent association between these variables could not be stated. These results support the clinician, as accuracy can provide a strong guide to the surgeon when planning surgical orthodontic treatment.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"271-279"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00988-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39216134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geranyl-geraniol addition affects potency of bisphosphonates-a comparison in vitro promising a therapeutic approach for bisphosphonate-associated osteonecrosis of the jaw and oral wound healing.","authors":"Marius Otto,&nbsp;Christine Lux,&nbsp;Tilo Schlittenbauer,&nbsp;Frank Halling,&nbsp;Thomas Ziebart","doi":"10.1007/s10006-021-00982-8","DOIUrl":"https://doi.org/10.1007/s10006-021-00982-8","url":null,"abstract":"<p><strong>Purpose: </strong>Analysis of the influence of geranyl-geraniol (GG) addition on four bisphosphonate derivatives regarding their influence on cell viability and migration ability of bone metabolism and endothelial cells in vitro.</p><p><strong>Methods: </strong>Clodronate, pamidronate, ibandronate, and zoledronate were observed with and without GG addition, for their effect on human osteoblasts (HOB), normal human dermal fibroblasts (NHDF), human endothelial progenitor cells (EPC), and endothelial cells of the human umbilical cord (HUVEC) using migration-, MTT-, and colony-forming cell assays.</p><p><strong>Results: </strong>Data pointed to a depressing effect of all bisphosphonates on the migration ability of NHDF, EPC, and HOB. MTT assay demonstrated a decreased cell viability of HUVEC of all bisphosphonates in a 50 μM concentration and of NHDF when treated with 50 μM of clodronate, ibandronate, or zoledronate. Tested drugs showed a depressing effect on colony-forming potential of EPC even in a 5 μM concentration. GG addition demonstrated an attenuate impact on bisphosphonate effect on all primary cell cultures, respectively.</p><p><strong>Conclusion: </strong>In vitro comparison showed that the addition of GG weakens the effect of all bisphosphonates examined. It supports investigations that suggest GG to be able to prevent bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ) in vivo. Future clinical trials may discover the local therapeutic use of GG for the prevention of BP-ONJ.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"321-332"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00982-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39311246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}