Oral and maxillofacial surgery最新文献

{"title":"Geranyl-geraniol addition affects potency of bisphosphonates-a comparison in vitro promising a therapeutic approach for bisphosphonate-associated osteonecrosis of the jaw and oral wound healing.","authors":"Marius Otto,&nbsp;Christine Lux,&nbsp;Tilo Schlittenbauer,&nbsp;Frank Halling,&nbsp;Thomas Ziebart","doi":"10.1007/s10006-021-00982-8","DOIUrl":"https://doi.org/10.1007/s10006-021-00982-8","url":null,"abstract":"<p><strong>Purpose: </strong>Analysis of the influence of geranyl-geraniol (GG) addition on four bisphosphonate derivatives regarding their influence on cell viability and migration ability of bone metabolism and endothelial cells in vitro.</p><p><strong>Methods: </strong>Clodronate, pamidronate, ibandronate, and zoledronate were observed with and without GG addition, for their effect on human osteoblasts (HOB), normal human dermal fibroblasts (NHDF), human endothelial progenitor cells (EPC), and endothelial cells of the human umbilical cord (HUVEC) using migration-, MTT-, and colony-forming cell assays.</p><p><strong>Results: </strong>Data pointed to a depressing effect of all bisphosphonates on the migration ability of NHDF, EPC, and HOB. MTT assay demonstrated a decreased cell viability of HUVEC of all bisphosphonates in a 50 μM concentration and of NHDF when treated with 50 μM of clodronate, ibandronate, or zoledronate. Tested drugs showed a depressing effect on colony-forming potential of EPC even in a 5 μM concentration. GG addition demonstrated an attenuate impact on bisphosphonate effect on all primary cell cultures, respectively.</p><p><strong>Conclusion: </strong>In vitro comparison showed that the addition of GG weakens the effect of all bisphosphonates examined. It supports investigations that suggest GG to be able to prevent bisphosphonate-associated osteonecrosis of the jaw (BP-ONJ) in vivo. Future clinical trials may discover the local therapeutic use of GG for the prevention of BP-ONJ.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"321-332"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00982-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39311246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The implant position accuracy between using only surgical drill guide and surgical drill guide with implant guide in fully digital workflow: a randomized clinical trial.","authors":"Chalermchai Ngamprasertkit,&nbsp;Weerapan Aunmeungthong,&nbsp;Pathawee Khongkhunthian","doi":"10.1007/s10006-021-00975-7","DOIUrl":"https://doi.org/10.1007/s10006-021-00975-7","url":null,"abstract":"<p><strong>Background: </strong>To evaluate and compare accuracy in position and inclination of a single-tooth implant placement using tooth-supported surgical drill guide (SDG) and surgical drill guide with implant insertion guide (SDIG) in fully digital workflow.</p><p><strong>Materials and methods: </strong>Thirty partially single edentulous patients were recruited. After randomization, participants were divided into 2 groups equally. The first group underwent implant placement through SDG only, while the second group was subjected to SDIG. All procedure proceeded under a fully digital workflow as the combination of digital scanning from an intraoral scanner, 3D radiographic images from cone-beam computed tomography (CBCT), implant planning software, and a 3D manufacturing machine. A post-operative CBCT was performed to compare the deviations (7 parameters) between planned and actual implant positions.</p><p><strong>Results: </strong>The mean global deviations at the shoulder and apex were 0.74 ± 0.36 and 1.29 ± 0.61 mm, respectively in the SDG group and 0.48 ± 0.22 mm and 0.71 ± 0.31 mm, respectively in the SDIG group. Likewise, the other parameters in the SDIG group showed fewer deviations than SDG for all measurements. Statistically significant differences were indicated by all parameters except for the horizontal deviation at the implant shoulder (p < .05).</p><p><strong>Conclusion: </strong>In single-tooth implant placement with a tooth-supported guide using a computer-assisted (static) system with the SDIG could reduce deviations of actual implant position when compared with using SDG only. Besides, guided implant surgery by fully digital workflow is a practical procedure and provides precise implant position regarding the prosthetic-driven concept.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"229-237"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00975-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39034322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proximity of mandibular third molar root(s) to surrounding cortical bone: cone beam computed tomography (CBCT) and panoramic findings.","authors":"Saowapap Wihokrut,&nbsp;Chakorn Vorakulpipat,&nbsp;Pattamawan Manosuthi,&nbsp;Aurasa Waikakul","doi":"10.1007/s10006-021-00979-3","DOIUrl":"https://doi.org/10.1007/s10006-021-00979-3","url":null,"abstract":"<p><strong>Purpose: </strong>We evaluated the relationship between mandibular third molar roots (M3Ms) and surrounding cortical bone using cone beam computed tomography (CBCT) and panoramic findings. We studied (a) the location of mandibular third molar roots in relation with cortical bone in terms of contact, penetration, and perforation on CBCT; (b) the relationship between characteristics of a root in panoramic findings and the CBCT image (entire and segmentally); and (c) the relationship of the root plane in panoramic findings vs. CBCT.</p><p><strong>Material and methods: </strong>One hundred five teeth with 224 roots of mandibular third molar from 73 patients were evaluated by using cone beam computed tomography and panoramic image.</p><p><strong>Result: </strong>The relationships were assessed using 105 images of impacted M3Ms: 104/105 (99%) showed cortical bone involvement (30.4% penetration and 68.6% perforation). The more apical the segment, the higher the proportion of perforation. Most (79.9%) of the M3M roots involved a lingual cortex with 46.9% penetration and 49.2% perforation. The panoramic signs of segmental root images-viz. clear and blurred-were not associated with cortical penetration or perforation. Panoramic signs of individual root images-in the same and different planes-could be used to predict root plane M3M roots. The same appearance in the panoramic image was significantly related to the same plane of the root in CBCT (p-value 0.048).</p><p><strong>Conclusion: </strong>These findings could contribute to enhanced radiological assessment and surgical planning.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"311-319"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00979-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39296714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term hard and soft tissue response following isolated genioplasty: a systematic review.","authors":"Jaymi Anna George,&nbsp;Annapurna Kannan,&nbsp;Vignesh Kailasam","doi":"10.1007/s10006-021-00991-7","DOIUrl":"https://doi.org/10.1007/s10006-021-00991-7","url":null,"abstract":"<p><strong>Purpose: </strong>Genioplasty facilitates alteration of the chin position and contour which contributes to aesthetics and function. The response of the hard and soft tissues following genioplasty has not been assessed after a year or more of the surgery being performed. Hence, the aim of this systematic review was to assess the response of the hard and soft tissues occurring at least 1 year after the procedure.</p><p><strong>Material and methods: </strong>A literature search was conducted in the following electronic databases: PubMed, Ovid, LILACS, and Cochrane Library. Potential articles were identified wherein only studies with genioplasty performed as an isolated procedure and with data at least 12 months after the procedure were included.</p><p><strong>Results: </strong>Five studies were included in this systematic review. Two of the articles included were considered to be of good quality while three were considered to be of moderate quality using a modified Downs and Black tool. The ROBINS-I tool showed a moderate risk of bias for most domains. The study characteristics revealed varying degrees of relapse for the hard and soft tissues.</p><p><strong>Conclusions: </strong>In the anteroposterior plane, the soft tissue relapsed more than the hard tissues 3 years post genioplasty. However, relapse in the vertical plane showed a wide variation for both the hard and soft tissues. In the anteroposterior plane, the hard tissue to soft tissue response 2 years or more following genioplasty ranged from 1:0.77 to 1:0.91 while in the vertical plane the hard tissue to soft tissue response ranged from 1:0.67 to 1:1.16.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"195-203"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00991-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39306129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spongiotic hyperplasia of the oral mucosa: case series and immunohistochemical analysis.","authors":"Heitor Albergoni Silveira,&nbsp;Victor Hugo Toral-Rizo,&nbsp;Edith Lara-Carrillo,&nbsp;Matheus Henrique Lopes Dominguete,&nbsp;Evânio Vilela Silva,&nbsp;Alfredo Ribeiro-Silva,&nbsp;Andreia Bufalino,&nbsp;Luciana Yamamoto Almeida,&nbsp;Jorge Esquiche León","doi":"10.1007/s10006-021-00996-2","DOIUrl":"https://doi.org/10.1007/s10006-021-00996-2","url":null,"abstract":"<p><p>The localized juvenile spongiotic gingival hyperplasia (LJSGH) mainly affects the maxillary vestibular attached gingiva of juvenile patients, without sex predilection. Similar lesions involving extragingival sites have not been reported to date. Here, we report 2 cases of extragingival soft tissue lesions with similar clinicopathological features to those reported in LJSGH and 12 cases of intraoral reactive soft tissue lesions microscopically showing LJSGH-like focal areas. The 2 cases were adult patients, affecting the maxillary alveolar ridge (55-year-old female) and hard palate (78-year-old male), which were diagnosed as \"spongiotic hyperplasia of the oral mucosa.\" The 12 intraoral reactive soft tissue lesions (6 men and 6 women; mean age, 49.5 years) were diagnosed as inflammatory fibrous hyperplasia (n = 6), peripheral ossifying fibroma (n = 3), and pyogenic granuloma (n = 3), each of them presenting LJSGH-like focal areas. By immunohistochemistry, the spongiotic hyperplasia areas showed positivity for CK19, CK14, CK34βE12, and CAM5.2 (weak/focal), while CK4 was negative. Considering the anatomical locations (extragingival) of these 2 cases, the term \"spongiotic hyperplasia of the oral mucosa\" is suggested. Moreover, LJSGH-like focal areas can be detected when microscopically assessing common intraoral reactive soft tissue lesions.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"333-337"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00996-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39318253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A volumetric study of mandibular condyles in orthognathic patients by semiautomatic segmentation.","authors":"Max-Philipp Lentzen,&nbsp;Maximilian Riekert,&nbsp;Johannes Buller,&nbsp;Andrea Grandoch,&nbsp;Matthias Zirk,&nbsp;Joachim E Zoeller,&nbsp;Matthias Kreppel","doi":"10.1007/s10006-021-00976-6","DOIUrl":"https://doi.org/10.1007/s10006-021-00976-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study was conducted to elucidate volumetric data of mandibular condyles of orthognathic patients by analyzing cone beam computed tomography images based upon semiautomatic segmentation.</p><p><strong>Methods: </strong>Cone beam computed tomography images of 87 patients with malocclusions were analyzed in this retrospective study. Patients were between 17 and 53 years old and diagnosed with Angle class I, II, or III malocclusion. By using the validated open-source software \"ITK-SNAP,\" the volumetric measurements of 174 mandibular condyles were performed. Volumetric analysis was performed according to intra-subject side differences by paired Student t test. In accordance to inter-subject side, gender, age and type of malocclusion differences bivariate analysis and ANOVA were applied.</p><p><strong>Results: </strong>The mean volume for the right condyle was 1.378 ± 0.447 cm³, with a maximum of 2.379 cm³ and a minimum of 0.121 cm³. The mean volume for the left side was 1.435 ± 0.474 cm³, with a maximum of 3.264 cm³ and a minimum of 0.109 cm³. Bivariate analysis indicated a highly significant inter-subject difference between the volume of the left and right mandibular condyles (p < 0.01). Females had a significantly smaller condyle volume than males (p < 0.05 left condyle; p < 0.01 right condyle).</p><p><strong>Conclusion: </strong>The fact that shape and volume of mandibular condyles show a high susceptibility to pathological alterations and particularly malocclusions makes a precise knowledge about volumetric changes indispensable. Our results show that significant inter-subject differences in condyle volume could be found with respect to the side and gender. Larger volumes could be assessed for the left condyle and for male patients.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"205-212"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00976-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39081904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Temporomandibular joint hematoma nerve block'-a new technique in management of mandibular condylar fractures.","authors":"Prajwalit Kende,&nbsp;Maroti Wadewale,&nbsp;Jayant Landge,&nbsp;Harsh Desai,&nbsp;Shambhavi Nadkarni,&nbsp;Mrimingsi Kri","doi":"10.1007/s10006-021-00987-3","DOIUrl":"https://doi.org/10.1007/s10006-021-00987-3","url":null,"abstract":"<p><strong>Purpose: </strong>Management of mandibular condylar fracture has invited a great deal of controversy in maxillofacial trauma care. In the orthopaedic literature, surgeons have exhaustively described the use of a 'hematoma block' technique during closed reduction (CR) of the ankle or other long bone fractures. Post-traumatic ankylosis of the temporomandibular joint (TMJ) is due to development and progression of the intra-articular hematoma. We improvised their technique for use during CR of mandibular condylar fractures. The desirable effects which can be achieved with our proposed 'novel TMJ hematoma nerve block' technique are evacuating the accumulated hematoma, blocking auriculotemporal and masseteric nerves which in turn causes relaxation of the lateral pterygoid muscle, all in all, favouring accurate anatomical reduction of the fracture.</p><p><strong>Method: </strong>Thirteen patients with isolated unilateral condylar fractures were subjected to our new technique. The parameters assessed were the amount of hematoma evacuated, pain in TMJ region during reduction and postoperative anatomic reduction on cone beam computed tomography (CBCT).</p><p><strong>Results: </strong>All the patients showed a significant reduction in pain and lowered post-reduction angulation between the proximal condylar and distal ramal segments.</p><p><strong>Conclusion: </strong>Our technique is minimally invasive, safe, simple to perform, yielding excellent anatomic reduction of the fracture fragments.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"247-251"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00987-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39168219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel prefabricated patient-specific titanium cranioplasty: reconsideration from a traditional approach.","authors":"Chinmaya Dash,&nbsp;Saubhik Dasukil,&nbsp;Kiran Kumar Boyina,&nbsp;Ritesh Panda,&nbsp;Suma Rabab Ahmad","doi":"10.1007/s10006-021-00977-5","DOIUrl":"https://doi.org/10.1007/s10006-021-00977-5","url":null,"abstract":"<p><strong>Objective: </strong>Patient-specific implants (PSI) for cranioplasty are expensive, and cost remains the limiting factor in low- to middle-income countries. The authors describe a novel, reproducible and cost-effective method of designing prefabricated titanium PSI cranioplasty.</p><p><strong>Methods: </strong>Ten patients from June 2018 to December 2020 were included in this retrospective study. A three-dimensional stereolithography model was made on a custom-built 3D printer with variable layer heights to produce efficient and accurate details. A certain amount of defect in the temporal region was left uncovered to avoid complications related to temporalis muscle dissection. The stereolithography model with a cranial defect was reconstructed with modelling wax. The wax model was scanned with a blue light visible scanner. The digital data was transferred to the milling machine (Jayon Surgical®, Kerala, India), where a 1-mm-thick sheet of titanium was milled according to the specifications. RFCC scoring system was used for assessing cosmetic outcome.</p><p><strong>Results: </strong>The mean duration of the surgery was 56.50 min, SD = 14.916 min (range 45-75 min). In 9/10 patients, the RFCC score was 4 points. No other complications were found at a minimum follow-up of 18 months in all patients. The cost per patient was approximately 30,000 INR or 400 US dollars. The average time required for us to get the PSI ready for surgery was about 15 days.</p><p><strong>Conclusion: </strong>The authors demonstrate a novel, cost-effective and reproducible method of PSI using titanium for cranioplasty.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"223-228"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00977-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39117235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential role of active decompression with distraction sugosteogenesis for the management of odontogenic cystic lesions: a retrospective review of 10 cases.","authors":"Sergio Trujillo-Saldarriaga,&nbsp;Mayra Alejandra Cuéllar,&nbsp;Carlos Alfaro-Portillo,&nbsp;Pedro Moreno-Rodríguez,&nbsp;Andrés Gómez-Delgado,&nbsp;Jaime Castro-Núñez","doi":"10.1007/s10006-021-00970-y","DOIUrl":"https://doi.org/10.1007/s10006-021-00970-y","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this paper is to describe active decompression and distraction sugosteogenesis as an alternative for the management of odontogenic cystic lesions. The technique, demographics, success rate, and complications will be presented.</p><p><strong>Patients and methods: </strong>A retrospective case series study design was implemented. This included patients found in our database from 2015 to 2018 with a diagnosis of any odontogenic cyst, in whom active decompression with distraction sugosteogenesis was implemented. The patient's medical history, demographics, radiographic characteristics of the cyst, technique/device employed, complications, and rate of success were recorded.</p><p><strong>Results: </strong>The sample consisted of 10 patients, with a mean age of 19.6 years (range 14-34). Sixty percent of all cases occurred in male patients and 40% in females. Forty percent of cases were consistent with odontogenic keratocysts with all cysts presenting in the mandible. No maxillary cases were documented. Seventy percent of such lesions were unilocular and 30% multilocular. Cortical fenestration/perforation was documented in 30% of cases and 1 pathologic fracture was seen. Active decompression was performed for an average of 37 days (range 30-50 days). With this system, radiographic resolution occurred in 1-3 months in 50% of cases, 6-12 months in 30% of cases, and 12 months in 20% of cases. Mean follow-up was 24.3 months. No recurrence was documented. Complications included fistula development (2 cases), flap dehiscence (1 case), and the size of the intraoral unit.</p><p><strong>Conclusions: </strong>This investigation reviewed the authors' 5-year experience employing active decompression with distraction sugosteogenesis for the management of odontogenic cystic lesions and showed that this is a reliable alternative for the management of odontogenic cysts.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"239-245"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00970-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39117326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does active decompression of odontogenic keratocyst change the histologic diagnosis?","authors":"Jaime Castro-Núñez,&nbsp;Andrés Gustavo Wiscovitch,&nbsp;Juan Pablo Porte,&nbsp;José Wiscovitch,&nbsp;Bonifacio Rivera,&nbsp;Lidia M Guerrero","doi":"10.1007/s10006-021-00994-4","DOIUrl":"https://doi.org/10.1007/s10006-021-00994-4","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this study was to compare the histopathologic findings of pre- and post-active decompression of odontogenic keratocyst and to establish if such findings were consistent.</p><p><strong>Materials and methods: </strong>A retrospective case series from a group of patients diagnosed with odontogenic keratocyst who underwent active decompression and distraction sugosteogenesis followed by final enucleation was designed and implemented. The dependent variable was changed in histologic diagnosis, as evaluated by an oral and maxillofacial pathologist. Other variables included age, gender, anatomic location of the lesion, and time elapsed from initial biopsy to final enucleation.</p><p><strong>Results: </strong>Six patients diagnosed with odontogenic keratocyst who underwent active decompression followed by enucleation and curettage were studied. The mean age was 45.6 years (range, 16 to 74) 83.33% were males, 16.66 females. Lesions were located in the mandible in 83.33% of cases and in the maxilla in 16.66% of cases. Post-active decompression histologic examination at the time of definitive enucleation was consistent with the initial diagnosis in 83.33% of cases.</p><p><strong>Conclusions: </strong>The histopathological diagnosis at the time of definitive treatment by enucleation and curettage is consistent with the pre-active decompression diagnosis.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"291-298"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-021-00994-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39255985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}