Oral and maxillofacial surgery最新文献

{"title":"Intraoral epidermoid cyst with extensive elastofibromatous changes: an unusual finding.","authors":"Heitor Albergoni Silveira,&nbsp;Luciana Yamamoto Almeida,&nbsp;Matheus Henrique Lopes Dominguete,&nbsp;Kamila Prado Pereira Graciano,&nbsp;Andreia Bufalino,&nbsp;Jorge Esquiche León","doi":"10.1007/s10006-019-00785-y","DOIUrl":"https://doi.org/10.1007/s10006-019-00785-y","url":null,"abstract":"<p><strong>Introduction: </strong>Epidermoid cysts (ECs) are rare and occur in the head and neck regions with an incidence from 1.6 to 7% of all cysts. In the oral cavity, approximately 80 ECs have been reported, representing less than 0.01% of all cysts.</p><p><strong>Case report: </strong>We report a case of a 26-year-old man who developed a large EC in the midline floor of the mouth causing nodular swelling in the submental region and speech and swallowing difficulties. The lesion was surgically excised by intraoral approach and microscopically revealed an EC associated with extensive elastofibromatous changes in the cystic capsule.</p><p><strong>Conclusion: </strong>Oral EC with extensive elastofibromatous changes is a finding extremely rare. The meaning of this finding is unknown, but a traumatic origin or deposit disorder of elastic fibers is suggested. To the best of our knowledge, intraoral EC with elastofibromatous changes has not been reported to date.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"493-497"},"PeriodicalIF":1.8,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-019-00785-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40562491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway management techniques in head and neck cancer surgeries: a retrospective analysis.","authors":"Rajnish Nagarkar,&nbsp;Gauri Kokane,&nbsp;Ashvin Wagh,&nbsp;Nayana Kulkarni,&nbsp;Sirshendu Roy,&nbsp;Ravindra Tandale,&nbsp;Samadhan Pawar","doi":"10.1007/s10006-019-00782-1","DOIUrl":"https://doi.org/10.1007/s10006-019-00782-1","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to conduct a retrospective analysis of modalities of airway management and its impact on patients undergoing head and neck cancer surgeries.</p><p><strong>Materials and methods: </strong>A retrospective review of the medical record of 500 patients operated from January 2008 to December 2013 was conducted at our institute. Patients were reviewed for a mode of airway management, a total length of post-operative hospital stay (PLOS), and incidence of elderly patients in the total number of head and neck cancer surgeries posted for various diagnostic and definitive treatments.</p><p><strong>Results: </strong>Out of 500 patients, 462 patients (92.4%) underwent nasal intubation, of which 320 underwent fiberoptic (FO) intubation (64%), 7 underwent tracheotomies after completion of surgery (1.4%), and 3 underwent at the beginning of surgery (0.6%). The remaining 38 patients (7.6%) underwent oral intubation.</p><p><strong>Conclusion: </strong>Nasotracheal intubation using fiberoptic bronchoscopy is the most preferred technique for the management of a difficult airway. Efficient airway management during the perioperative period significantly reduces the post-operative length of hospital stay and morbidity.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"311-315"},"PeriodicalIF":1.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-019-00782-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40450928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental intervention against osteoradionecrosis of the jaws in irradiated patients with head and neck malignancy: a single-arm prospective study.","authors":"Yumi Muraki,&nbsp;Masaya Akashi,&nbsp;Yasuo Ejima,&nbsp;Takumi Hasegawa,&nbsp;Daisuke Miyawaki,&nbsp;Hirotaka Shinomiya,&nbsp;Mika Nishii,&nbsp;Naoki Otsuki,&nbsp;Ryohei Sasaki,&nbsp;Ken-Ichi Nibu,&nbsp;Takahide Komori","doi":"10.1007/s10006-019-00783-0","DOIUrl":"https://doi.org/10.1007/s10006-019-00783-0","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to investigate the effectiveness of dental intervention before and after radiation therapy (RT) for head and neck malignancy on prevention of osteoradionecrosis (ORN) of the jaws.</p><p><strong>Methods: </strong>This is a single-arm prospective study according to intervention protocol of prophylactic dental extraction before RT and routine follow-up after RT. The primary endpoint was the occurrence of jawbone exposure during the first 2 years after RT.</p><p><strong>Results: </strong>Sixty-seven patients were assessed. Before RT, 144 teeth among 39 patients (58%) were prophylactically extracted. The occurrence of transient jawbone exposure during the first 2 years after RT was 7%. Because those jawbone exposures healed with intervention after RT, no jawbone exposure was found at 2 years after RT.</p><p><strong>Conclusions: </strong>Dental intervention both before and after RT seemed to be important to prevent ORN development. Further studies in larger cohorts are necessary.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"297-305"},"PeriodicalIF":1.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-019-00783-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40539936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the impact of computerised and written advice in changing the habit and behaviour of alcohol use in patients who have suffered alcohol-related facial injuries-a pilot study.","authors":"Kai Lee,&nbsp;Hao-Hsuan Tsai,&nbsp;Jiandong Sun,&nbsp;Arun Chandu","doi":"10.1007/s10006-019-00749-2","DOIUrl":"https://doi.org/10.1007/s10006-019-00749-2","url":null,"abstract":"<p><strong>Purpose: </strong>Alcohol screening and a brief intervention (SBI) can be effective in changing harmful drinking behaviour and reducing the chance of future alcohol-related traumas. However, there is no standardised method in its application. This study aims to deliver a novel method of SBI to patients with alcohol-related facial fractures and to assess changes in their alcohol intake and attitudes to drinking following this intervention.</p><p><strong>Methods: </strong>Twenty consecutive patients at two Victorian Hospitals were consented to undergo a novel SBI program. This study analysed the results of the initial survey and the follow-up survey completed at least 3 months later.</p><p><strong>Results: </strong>Of the 20 patients recruited for the initial survey, 18 returned for the follow-up (90% response rate). All patients were males, 50% were aged between 18 and 29 years, 61% involved in interpersonal violence, 56% sustained mandibular fractures and 89% underwent surgery. The alcohol risk score increased in the follow-up survey; however, the relationship is not statistically significant. A high proportion of the patients were still unaware of their risk. Patients showed greater awareness of their drinking and willingness to accept help and more readiness to accept written advice rather than computerised materials.</p><p><strong>Conclusion: </strong>This study found a high rate of acceptance among trauma patients to the intervention program. Although there was no significant change in the risk scores between the initial and follow-up surveys, certain subgroup was more amenable to the intervention given. There is generally an improvement in the attitudes towards and knowledge of harmful drinking.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"149-157"},"PeriodicalIF":1.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-019-00749-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40547165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity of the 3D VECTRA photogrammetric surface imaging system for cranio-maxillofacial anthropometric measurements.","authors":"Philipp Metzler,&nbsp;Yi Sun,&nbsp;Wolfgang Zemann,&nbsp;Alexander Bartella,&nbsp;Marc Lehner,&nbsp;Joachim Anton Obwegeser,&nbsp;Astrid L Kruse-Gujer,&nbsp;Heinz-Theo Lübbers","doi":"10.1007/s10006-013-0404-7","DOIUrl":"https://doi.org/10.1007/s10006-013-0404-7","url":null,"abstract":"<p><strong>Purpose: </strong>The use of three-dimensional (3D) photography for anthropometric measurements is of increasing interest, especially in the cranio-maxillofacial field. Before standard implementation, accurate determination of the precision and accuracy of each system is mandatory.</p><p><strong>Methods: </strong>A mannequin head was labelled with 52 landmarks, and 28 three-dimensional images were taken using a commercially available five-pod 3D photosystem (3D VECTRA; Canfield, Fairfield, NJ) in different head positions. Distances between the landmarks were measured manually using a conventional calliper and compared with the digitally calculated distances acquired from labelling by two independent observers. The experimental set-up accounted for clinical circumstances by varying the positioning (vertical, horizontal, sagittal) of the phantom.</p><p><strong>Results: </strong>In the entire calliper measurement data set (n = 410), a significant difference (p = 0.02) between the directly measured and corresponding virtually calculated distances was found. The mean aberration between both modalities covering all data was 7.96 mm. No differences (p = 0.94) between the two groups were found using a cut-off of 10 % (leaving n = 369 distances) due to considerable errors in direct measurements and the necessary manual data translation. The mean diversity of both measurement modalities after cut-off was 1.33 mm (maximum, 6.70 mm). Inter-observer analysis of all 1,326 distances showed no difference (p = 0.99; maximal difference, 0.58 mm) in the digital measurements.</p><p><strong>Conclusion: </strong>The precision and accuracy of this five-pod 3D photosystem suggests its suitability for clinical applications, particularly anthropometric studies. Three-hundred-and-sixty degree surface-contour mapping of the craniofacial region within milliseconds is particularly useful in paediatric patients. Proper patient positioning is essential for high-quality imaging.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"297-304"},"PeriodicalIF":1.8,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-013-0404-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40248720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillofacial trauma and seat belt: a 10-year retrospective study.","authors":"Marcelo Mendes,&nbsp;Márcia Borba,&nbsp;Renato Sawazaki,&nbsp;Luciana Asprino,&nbsp;Márcio de Moraes,&nbsp;Roger Willians Fernandes Moreira","doi":"10.1007/s10006-012-0323-z","DOIUrl":"https://doi.org/10.1007/s10006-012-0323-z","url":null,"abstract":"<p><strong>Introduction: </strong>Brazil is among the countries with the highest prevalence of people injured by traffic accidents, showing that in 2008, levels reached 18.3 victims for 100,000 habitants were victims of traffic accidents.</p><p><strong>Materials and methods: </strong>This retrospective study involved data collected from treated patients' charts at seven different hospitals located in three different cities all in the state of São Paulo, Brazil. Information was obtained through a standardized form, which was designed to investigate the epidemiologic features of maxillofacial traumas, restricted to victims of car accidents.</p><p><strong>Results: </strong>Three hundred ninety-six patients were victims of car crashes with mean age 29.75 years. The age group 18-30 years showed an association with facial trauma in 96 patients, 41.56 % of whom reported using seat belt. Le Fort I, II and III (70 %) and mandible (63.11 %) were more associated with body traumas and seat belt use. The most common soft tissue lesion was laceration with 189 cases (42.3 %). The treatment way was assessed, 93 (23 %) were treated surgically and 303 (77 %) underwent conservative treatment.</p><p><strong>Discussion: </strong>Classically, it is known front seat belt use was positively correlated with back seat belt use, healthy diet, dental and general health, regular walking, adequate sleep and no smoking. Accidents involving cars occurred more frequently in age group 18-30 years, suffering more general traumas and representing the nonusers group that wore fewer seat belts, caused, perhaps, by bigger access of the youth to cars, driving in high speed and to an inefficient fiscalization of the traffic laws.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"21-5"},"PeriodicalIF":1.8,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-012-0323-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40550663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare case of superolateral dislocation of the condyle.","authors":"Sathish Radhakrishna,&nbsp;Bindu Ramesh","doi":"10.1007/s10006-012-0322-0","DOIUrl":"https://doi.org/10.1007/s10006-012-0322-0","url":null,"abstract":"<p><strong>Background: </strong>Dislocation of the mandibular condyle occurs most commonly in the anterior direction. When there is an intracranial displacement of the condyle, it is often associated with CSF leak. Superolateral dislocation of the condyle from the glenoid fossa is a rare condition which commonly occurs following traumatic insult to the mandible. When there is a superlolateral displacement, the condyle is often lodged in the temporal fossa.</p><p><strong>Case report: </strong>We report an unusual case of a 50-year-old male with a superolateral dislocation of the left mandibular condyle into the zygomatic arch along with a fracture of the right mandible following road traffic accident. Manual reduction of the condyle was first attempted under general anaesthesia which was futile, following which the displaced condyle was reduced by a combination of open traction and manual reduction using Keen's approach in left maxillary vestibule. After reduction of the condyle, intermaxillary fixation (IMF) was done and X plate was used to fix the mandible fracture on the right body. Postoperatively, patient was placed on IMF for a period of 2 weeks.</p><p><strong>Discussion: </strong>Superolateral dislocations of the condyle can be unilateral or bilateral. These types of dislocations generally occur following traumatic injury to the mandible when the mouth is open. Early diagnosis and reduction of the condyle is required to achieve satisfactory occlusion which should be followed by physiotherapy to prevent ankylosis.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"59-61"},"PeriodicalIF":1.8,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-012-0322-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40177921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple primary enoral soft tissue manifestations of a Hodgkin lymphoma--case report and literature review.","authors":"P W Kämmerer,&nbsp;E Schiegnitz,&nbsp;T Hansen,&nbsp;G F Draenert,&nbsp;H D Kuffner,&nbsp;M O Klein","doi":"10.1007/s10006-012-0321-1","DOIUrl":"https://doi.org/10.1007/s10006-012-0321-1","url":null,"abstract":"<p><strong>Background: </strong>Hodgkin lymphoma (HL) are lymphoproliferative neoplasms, histologically comprising of mononuclear and multinucleated Hodgkin and Reed Sternberg cells (HRS). About 4 % of all lymphatic malignancies of the head and neck are HL. The typical disease presents itself as a nodal lesion. Extranodal, enoral soft tissue involvement by HL is very rare.</p><p><strong>Case report: </strong>A 73-year-old man with a suspect, ulcerating lesion in the left retromolar region of the mandible was assigned to our hospital. Prior anti-inflammatory therapy has been without success. Subsequently, three biopsies were taken which could only show inflammation. Finally, two biopsies from the left retromolar region and the left inner cheek showed HRS cells with positive expressions of CD15 and CD30 corresponding to a Hodgkin lymphoma. No lymphatic node or bone involvement could be detected. The patient was designated to receive radio-chemotherapy, but died 3 weeks after diagnosis of multiple organ failure. In a literature review, together with this report, nine cases were found concerning primary HL of the oral mucosa. Accordingly, this is the first case of primary multiple extranodal HL in the oral mucosa in absence of lymphatic node involvement.</p><p><strong>Discussion: </strong>Neither clinical features nor radiological appearances of HL presenting as primary enoral lesions are pathognomonic. Especially when only small biopsy specimens are available, histological diagnosis remains challenging, may lead to a delay in therapy and may result in a significant worse prognosis.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"53-7"},"PeriodicalIF":1.8,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-012-0321-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40177920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epithelioid myoepithelioma of the hard palate.","authors":"Atsushi Kasamatsu,&nbsp;Masashi Shiiba,&nbsp;Dai Nakashima,&nbsp;Ken Shimada,&nbsp;Morihiro Higo,&nbsp;Takashi Ishigami,&nbsp;Shunsaku Ishige,&nbsp;Katsunori Ogawara,&nbsp;Hideki Tanzawa,&nbsp;Katsuhiro Uzawa","doi":"10.1007/s10006-012-0324-y","DOIUrl":"https://doi.org/10.1007/s10006-012-0324-y","url":null,"abstract":"<p><strong>Background: </strong>Myoepithelioma, a generally benign tumor comprised of myoepithelial cells, is an uncommon salivary gland tumor. Among four morphologic variants of myoepithelioma, epithelioid type has not been reported in the oral and maxillofacial region.</p><p><strong>Case report: </strong>A 61-year-old man first noticed the mass 3 years previously. The oral examination revealed a firm, non-tender, and well-circumscribed mass in the middle of the hard palate. A magnetic resonance imaging scan showed a well-circumscribed mass with low signal intensity (T(1)-weighted image) or increased signal intensity (T(2)-weighted image).</p><p><strong>Discussion: </strong>Immunohistochemically, the tumor cells in the present case reacted to the epithelial (CK HMW and CAM5.2) and the mesenchymal (vimentin) markers. However, myoepithelial markers (S-100 protein, α-smooth muscle actin, glial fibrillary acidic protein, and calponin), except p63, were not expressed in the tumor cells. These results indicated that the epithelial myoepithelioma cells differentiated into epithelial cells rather than myoepithelial cells. We believe that epithelioid myoepithelioma of the palate is a distinctive subtype of myoepithelioma that should be included in the differential diagnosis of tumors of the palate.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"63-6"},"PeriodicalIF":1.8,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-012-0324-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40177922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandibular fracture scoring system: for prediction of complications.","authors":"D Prabhu Shankar,&nbsp;P Manodh,&nbsp;Pradeep Devadoss,&nbsp;Titus K Thomas","doi":"10.1007/s10006-012-0326-9","DOIUrl":"https://doi.org/10.1007/s10006-012-0326-9","url":null,"abstract":"<p><strong>Introduction: </strong>Mandibular fractures are one of the most commonly encountered injuries in trauma clinics. Although several widely accepted classification systems exist, these are mostly region specific, differ in the classification criteria used, and are sometimes only correlated with specific treatment modalities, thereby making it impossible to uniformly and comprehensively document facial fracture patterns. In this study, we developed a modified scoring system for mandibular fractures and analyzed the relationship between scoring of fractures that were treated and the incidence of complications after surgical treatment.</p><p><strong>Materials and methods: </strong>To evaluate the suitability of the proposed scoring system, a prospective study on a series of 116 patients was performed. All the fractures were classified using the proposed scoring system. The scoring was based on clinical and radiological evaluation of each fracture. Patients were followed up postoperatively for presence of complications.</p><p><strong>Results: </strong>A good correlation between the proposed scoring system and the incidence of complications was detected.</p><p><strong>Discussion: </strong>This scoring system for mandibular fractures facilitates an objective and standardized assessment of the degree of severity of a fracture, thereby allowing for systematic evaluation of facial fracture outcomes, including assessment of complications. However, it is our understanding that a multicenter study should be performed before the effectiveness of the proposed classification can be clearly stated.</p>","PeriodicalId":520733,"journal":{"name":"Oral and maxillofacial surgery","volume":" ","pages":"355-60"},"PeriodicalIF":1.8,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10006-012-0326-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40187934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}