Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale最新文献

{"title":"Italian translation, cross-cultural adaptation and validation of the Mayo Clinic Vestibular Schwannoma Quality of Life (VSQOL) Index.","authors":"Alessandra Eleuteri, Cecilia Botti, Alessandro Rosti, Filippo Friso, Carlo Bortolotti, Carmelo Sturiale, Alfredo Conti, Gabriele Molteni, Livio Presutti, Giulia Molinari","doi":"10.14639/0392-100X-A1549","DOIUrl":"10.14639/0392-100X-A1549","url":null,"abstract":"<p><strong>Background: </strong>The Mayo Clinic Vestibular Schwannoma Quality of Life (VSQOL) Index is a disease-specific instrument for assessing health-related quality of life (HRQoL) in patients with sporadic vestibular schwannoma (VS). To date, there is no validated Italian version of this questionnaire.</p><p><strong>Objectives: </strong>This study aimed to translate, culturally adapt, and validate the VSQOL Index Version 2 in Italian (Italian VSQOL Index) while assessing its psychometric properties.</p><p><strong>Methods: </strong>The VSQOL Index Version 2 was translated and culturally adapted according to the Functional Assessment of Chronic Illness Therapy (FACIT) methodology. A cohort of 39 Italian-speaking VS patients completed the Italian VSQOL Index alongside the Penn Acoustic Neuroma Quality of Life (PANQOL) Scale, the 36-Item Short Form Health Survey (SF-36), and the 21-Item Depression, Anxiety, and Stress Scale (DASS-21). Internal consistency (Cronbach's α), test-retest reliability (intraclass correlation coefficient, ICC), and construct validity were analysed.</p><p><strong>Results: </strong>The Italian VSQOL Index demonstrated excellent internal consistency, with Cronbach's α ranging from 0.89 to 0.95 across its domains, and high test-retest reliability, indicated by an ICC ranging from 0.78 to 0.92 among the domains. Significant correlations with PANQOL, SF-36, and DASS-21 scores confirmed convergent validity. Patients received the questionnaire positively, with no major comprehension issues reported during cognitive debriefing.</p><p><strong>Conclusions: </strong>The Italian VSQOL Index is a valid and reliable instrument for assessing HRQoL in Italian-speaking VS patients. Its application in clinical practice and research will enhance the evaluation of disease impact and treatment outcomes within this population.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 3","pages":"228-237"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148298589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Side correlation between subjective visual vertical tilt and symptoms in migraine with vertigo.","authors":"Mario Faralli, Francesco Gennari, Vincenzo Marcelli, Beatrice Giannoni, Matteo Paniconi, Giampietro Ricci, Davide Stivalini","doi":"10.14639/0392-100X-A1670","DOIUrl":"10.14639/0392-100X-A1670","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the subjective visual vertical (SVV) in migraine patients with balance disorders and its correlation with symptoms. We hypothesise that vestibular imbalance reflects a global migraine activation leading to symptom prevalence on one side.</p><p><strong>Methods: </strong>Twenty-six migraine patients with vertigo and/or dizziness (Group A) were studied in the interictal period. Symptoms assessed: unilateral (U) vs bilateral (B) headache (H), cranial autonomic (CAS) or cochlear symptoms (CS), vertigo/dizziness. SVV test was performed in all participants. Group A was compared to Group B (migraine without vertigo/dizziness) and Group C (controls). Main parameters: SVV0 (mean tilt in 6 trials) and SVV side exclusivity (SE: tilt of same sign in ≥ 5 trials).</p><p><strong>Results: </strong>SVV0A (0.80 ± 0.68) was significantly greater than SVV0B (0.39 ± 0.40; p = 0.01) and SVV0C (0.32 ± 0.19; p = 0.001). SVV SE was found in 78.6% of patients with vertigo and 18.7% with dizziness (p = 0.003). SVV SE incidence was higher in UH (64.7%) <i>vs</i> BH (11.1%; p = 0.02), and in UCAS (72.7%) and UCS (85.7%) <i>vs</i> BCAS/none (26.6%) and BCS/none (31.6%) (p = 0.02; p = 0.04).</p><p><strong>Conclusions: </strong>A slight SVV tilt persists between vertigo attacks and correlates with migraine imbalance underlying side-prevalent symptoms.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 3","pages":"238-245"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148298597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-cultural adaptation of the Italian Chronic Rhinosinusitis Patient-Reported Outcome. Questionnaire.","authors":"Antonino Maniaci, Luca Giovanni Locatello, Gian Luca Fadda, Paolo Boscolo-Rizzo, Eugenio De Corso, Jérôme R Lechien, Christian Calvo-Henriquez, Leigh J Sowerby, Alberto Maria Saibene","doi":"10.14639/0392-100X-A1672","DOIUrl":"10.14639/0392-100X-A1672","url":null,"abstract":"<p><strong>Objective: </strong>The Chronic Rhinosinusitis Patient-Reported Outcome (CRS-PRO) is a validated 12-item tool for assessing symptom burden in chronic rhinosinusitis (CRS). Although cross-culturally validated in other languages, there is no Italian version. This study aimed to translate, adapt, and validate the CRS-PRO for Italian-speaking patients.</p><p><strong>Methods: </strong>We conducted a prospective multicentre study in 5 Italian otolaryngology centres (Jan 2024 - Aug 2025). Translation and adaptation followed International Society for Pharmacoeconomics and Outcomes Research guidelines. Participants were adults with CRS without polyps (CRSsNP), with polyps (CRSwNP), and healthy controls. Psychometric testing included internal consistency (Cronbach's α, McDonald's ω), test-retest reliability (Intraclass Correlation Coefficient, ICC), Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) factor analyses, and construct validity.</p><p><strong>Results: </strong>A total of 118 participants were enrolled (controls = 32, CRSsNP = 40, CRSwNP = 46). Internal consistency was moderate (Cronbach's α = 0.669) but excellent (McDonald's ω = 0.946). Reliability was high (ICC = 0.92). EFA supported a two-factor solution (physical, psychological), explaining 73.4% of the total variance. CFA confirmed this model (CFI = 0.978, TLI = 0.972, SRMR = 0.109), with strong interfactor correlation (r = 0.93). CRSwNP patients reported the highest burden.</p><p><strong>Conclusions: </strong>The Italian CRS-PRO showed strong reliability, validity, and factorial structure, supporting its clinical and research use.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 3","pages":"213-219"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148298214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel approach to hearing amplification: audiometric outcomes from Nuance Audio over-the-counter hearing aid glasses.","authors":"Andrea Albera, Marco Boldreghini, Luca Girotto, Roberto Albera, Claudia Cassandro, Andrea Canale","doi":"10.14639/0392-100X-A1581","DOIUrl":"10.14639/0392-100X-A1581","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the first audiometric outcomes of Nuance Audio hearing glasses, an over-the-counter solution integrating air conduction amplification technology into standard eyeglass frames, in individuals with mild to moderate hearing loss.</p><p><strong>Methods: </strong>Thirty-two adults (mean age 74 years) with symmetric, age-related mild to moderate sensorineural hearing loss were tested. Pure-tone and speech audiometry were performed under unaided and aided free-field conditions. Device settings were adjusted via smartphone app based on audiometric profiles and user preference. Paired t-tests assessed the differences.</p><p><strong>Results: </strong>Nuance Audio glasses significantly improved hearing thresholds, especially at 4000-6000 Hz, with mean gains of 10-11 dB HL. Speech reception thresholds improved by 7 dB at 50% intelligibility and 6 dB at 100%. Amplification profile preferences matched audiometric slopes and no differences in benefit were found between mild and moderate hearing loss groups.</p><p><strong>Conclusions: </strong>Nuance Audio glasses provide clinically relevant improvements in pure-tone and speech thresholds for adults with mild to moderate presbycusis. Their discreet, open-ear design and self-fitting approach address barriers to traditional hearing aids and may support earlier adoption.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 3","pages":"220-227"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148298231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hidden diagnosis in the tonsil: recognising and differentiating intratonsillar abscess.","authors":"Kadir Sinasi Bulut, Fatih Gul, Ali Ozturk, Tuba Saadet Deveci Bulut, Serkan Serifler, Burak Celik, Mehmet Ali Babademez","doi":"10.14639/0392-100X-A1288","DOIUrl":"10.14639/0392-100X-A1288","url":null,"abstract":"<p><strong>Objective: </strong>Peritonsillar abscess (PTA) and intratonsillar abscess (ITA) are distinct entities, but the latter is often overlooked due to its rarity and diagnostic difficulty. This study compares their clinical, laboratory, and microbiological profiles to identify distinguishing features.</p><p><strong>Methods: </strong>This single-centre retrospective study included 367 patients diagnosed with PTA (n = 311) or ITA (n = 56) between 2019 and 2025. Demographics, symptoms, laboratory markers (e.g., white blood cells [WBC], neutrophils, lymphocytes, large unstained cells [LUC], C-reactive protein, sodium, neutrophil-to-lymphocyte ratio, systemic immune-inflammation index, and platelet-to-WBC ratio [PWR]), culture results, imaging, drainage outcomes, and hospital stay were analysed comparatively.</p><p><strong>Results: </strong>PTA cases showed significantly higher WBC, neutrophil counts, and drainage volumes, with 80.8% drainage success <i>versus</i> 19.1% in ITA (p < 0.001). LUC and PWR were significantly elevated in ITA, suggesting a lymphocyte-dominant response. Fever was more frequent in ITA, while trismus and local spread were more characteristic of PTA.</p><p><strong>Conclusions: </strong>ITA typically presents with smaller abscesses and limited systemic involvement, often responding to conservative treatment. Recognising ITA as a distinct clinical entity may improve diagnosis and management strategies.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 3","pages":"194-202"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic lesions of the cervical trachea: conservative or surgical treatment? A systematic review.","authors":"Cecilia Molendi, Davide Lancini, Alessandra Sordi, Cesare Piazza","doi":"10.14639/0392-100X-A1557","DOIUrl":"10.14639/0392-100X-A1557","url":null,"abstract":"","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 3","pages":"172-185"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148298564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Videomics and artificial intelligence in endoscopic diagnosis of laryngeal lesions: mapping current evidence through a scoping review.","authors":"Alessandro Ioppi, Elisa Bellini, Maria Sofia Salvetta, Filippo Marchi, Domenico di Maria, Giorgio Peretti, Pasquale D'Alessio, Pietro Perotti, Ottavio Piccin, Claudio Sampieri","doi":"10.14639/0392-100X-suppl.1-46-2026-A1967","DOIUrl":"10.14639/0392-100X-suppl.1-46-2026-A1967","url":null,"abstract":"","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 Suppl. 1","pages":"S19-S33"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147978307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a role for adjuvant radiotherapy after partial laryngectomy? A propensity score matched analysis.","authors":"Liliana Belgioia, Ida D'Onofrio, Marta Filauro, Andrea Iandelli, Filippo Marchi, Francesco Mora, Almalina Bacigalupo, Luca Boni, Luca Carmisciano, Francesca Di Pressa, Alicia Tosoni, Vincenzo Della Peruta, Matteo Fermi, Francesco Mattioli, Cesare Guida, Giuseppe Tortoriello, Livio Presutti, Giorgio Peretti, Elisa D'Angelo","doi":"10.14639/0392-100X-suppl.1-46-2026-A2292","DOIUrl":"10.14639/0392-100X-suppl.1-46-2026-A2292","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of postoperative radiotherapy (PORT) on survival outcomes in patients with laryngeal cancer treated with partial laryngectomy.</p><p><strong>Methods: </strong>In this retrospective multicentre study, 312 patients with supraglottic or glottic squamous cell carcinoma treated with transoral laser microsurgery (TLM) or open partial horizontal laryngectomy (OPHL), with or without PORT between 2005 and 2022 were analysed. Propensity score modelling and inverse probability weighting were applied to balance baseline characteristics. Endpoints included disease-free survival (DFS), overall survival (OS), disease-specific survival (DSS), and locoregional control (LRC).</p><p><strong>Results: </strong>Of 312 patients, 175 underwent surgery alone and 137 received PORT. Treated patients had more adverse features. PORT significantly improved DFS (hazard ratio [HR] 0.44, 95% confidence interval [CI] 0.25-0.77) and LRC (HR 0.06, 95% CI 0.01-0.25). A significant benefit was also observed for DSS (HR 0.40, 95% CI 0.18-0.92). No statistically significant difference in OS emerged (HR 0.75, 95% CI 0.40-1.37).</p><p><strong>Conclusions: </strong>PORT significantly improves DFS and LRC after partial laryngectomy in high-risk patients, supporting its role in carefully selected cases.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 Suppl. 1","pages":"S100-S108"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147978242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salvage open partial horizontal laryngectomy: a comprehensive systematic review of oncological and functional outcomes.","authors":"Andy Bertolin, Alberto Grassetto, Marco Lionello, Giuseppe Rizzotto, Vincenzo Della Peruta, Luigi D'Avino, Marco de Vincentiis, Giovanni Succo, Giuseppe Tortoriello","doi":"10.14639/0392-100X-suppl.1-46-2026-A2207","DOIUrl":"10.14639/0392-100X-suppl.1-46-2026-A2207","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the oncological and functional outcomes of salvage open partial horizontal laryngectomy (OPHL) following failure of transoral laser microsurgery (TOLMS) (chemo)radiotherapy [(C)RT].</p><p><strong>Methods: </strong>A comprehensive systematic review was conducted, analysing survival rates (overall survival [OS], disease-specific survival [DSS], and local control [LC]), laryngeal preservation, and functional recovery (decannulation and swallowing) in the salvage setting.</p><p><strong>Results: </strong>Salvage OPHL offers oncological outcomes comparable to total laryngectomy (TL) in strictly selected patients. Meta-analyses report 5-year OS rates of 71-83% and LC around 87%. Outcomes are significantly superior for post-TOLMS recurrences compared to post-(C)RT failures. In the post-TOLMS setting, organ preservation reaches 95.3%. Conversely, irradiated tissues are prone to higher morbidity, including chronic oedema, chondronecrosis, and pexy rupture. While functional recovery is substantially longer after RT - with decannulation and nasogastric feeding tube removal times often doubling - the final success rate remains high, with over 90% of patients regaining oral feeding and airway patency within one year.</p><p><strong>Conclusions: </strong>Salvage OPHL is a powerful organ-preservation tool. Success depends on rigorous patient selection, accurate restaging (addressing frequent clinical understaging), and the preservation of at least one functional cricoarytenoid unit. While functionally demanding, it provides a superior quality of life compared to TL by avoiding a permanent tracheostoma and maintaining laryngeal voice.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 Suppl. 1","pages":"S56-S63"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147978329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crico-tracheal resection and anastomosis for primary and secondary tumours of the laryngo-tracheal junction: a single centre series of 78 patients.","authors":"Davide Lancini, Cecilia Molendi, Francesca Del Bon, Gabriele Zigliani, Claudia Montenegro, Giulia Belponer, Gabriele Testa, Piero Nicolai, Cesare Piazza","doi":"10.14639/0392-100X-suppl.1-46-2026-A2012","DOIUrl":"10.14639/0392-100X-suppl.1-46-2026-A2012","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to analyse data related to (crico-)tracheal resection and anastomosis [(C)TRA] for primary or secondary tumours involving the laryngo-tracheal junction, focusing on clinical indications, oncological, and functional outcomes.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients treated by (C)TRA from September 1996 to October 2025 in a single academic tertiary referral centre. Patients were distinguished into 5 subgroups based on tumour histology as: 1) advanced thyroid carcinomas involving the airway, 2) cricoid and tracheal chondrosarcomas, 3) minor salivary gland tumours, 4) squamous cell carcinomas, and 5) other rarer histotypes. Primary endpoints included overall (OS), disease-specific (DSS), and laryngectomy-free survivals (LFS).</p><p><strong>Results: </strong>The cohort consists of 78 patients submitted to 80 (C)TRA distributed among Types A, B, C, and E. The most frequent histotypes were advanced thyroid carcinomas and chondrosarcomas. The final decannulation rate was 97.4% with an overall complication rate of 27.5%. Five-year OS, DSS, and LFS were 65.4, 76.7, and 95%, respectively.</p><p><strong>Conclusions: </strong>(C)TRA represents an effective surgical strategy for tumours involving the laryngo-tracheal junction, preserving laryngeal functions without compromising oncologic prognosis. Outcomes are excellent for well-differentiated thyroid or cartilaginous tumours, while caution is warranted in high-grade histologies, extrinsic infiltration from metastatic lymph nodes, or previously irradiated patients.</p>","PeriodicalId":520544,"journal":{"name":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","volume":"46 Suppl. 1","pages":"S73-S81"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147978250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}