Long-term outcomes and quality of life following parotidectomy for benign disease.

Michaela Plath, Matthias Sand, Carlo Cavaliere, Peter K Plinkert, Ingo Baumann, Karim Zaoui
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Abstract

Objective: Parotidectomy worsens quality of life (QoL) in the short-term, but the long-term impact is unknown. In this study, we analysed the long-term effects of parotidectomy on QoL.

Methods: In this prospective long-term follow-up study, participants were divided into three groups: short-term (ST) follow-up of six weeks, long-term (LT) follow-up of 13 years and short- and long-term (SLT) follow-up. QoL was assessed using the Parotidectomy Outcome Inventory (POI-8). Parotidectomies were classified based on whether the great auricular nerve (GAN) had been preserved or sacrificed.

Results: In total, 164 observations were analysed, 74 in the LT group, 57 in the ST group and 33 in the SLT group. Hypoaesthesia was a major problem and facial palsy was a minor problem. Pain (p < 0.01) and hypoaesthesia (p < 0.001) were significantly lower after 13 years compared with after six weeks, and QoL was higher after 13 years compared with after six weeks (p = 0.04). The disease-specific impairment rate decreased from 70% at short-term follow-up to 30% at long-term follow-up. Removal of the GAN was associated with hypoaesthesia in the ST group (p = 0.028).

Conclusions: Hypoaesthesia has a long-term impact on the QoL, and this should be emphasised during preoperative discussions.

Abstract Image

Abstract Image

良性疾病腮腺切除术后的长期预后和生活质量。
目的:腮腺切除术使患者的生活质量(QoL)在短期内恶化,但其长期影响尚不清楚。在本研究中,我们分析了腮腺切除术对生活质量的长期影响。方法:本前瞻性长期随访研究将参与者分为3组:短期(ST)随访6周,长期(LT)随访13年,短期和长期(SLT)随访。使用腮腺切除术结局量表(POI-8)评估生活质量。腮腺切除术的分类依据是是否保留或牺牲了大耳神经(GAN)。结果:共分析164例观察,其中LT组74例,ST组57例,SLT组33例。感觉减退是主要问题,面瘫是次要问题。治疗13年后疼痛(p < 0.01)和感觉减退(p < 0.001)明显低于治疗6周后,治疗13年后生活质量明显高于治疗6周后(p = 0.04)。疾病特异性损伤率从短期随访的70%下降到长期随访的30%。ST组GAN的移除与感觉减退相关(p = 0.028)。结论:麻醉减退对生活质量有长期影响,在术前讨论时应强调这一点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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