Nada Shurab , Anju Sharma , Eman Al Maslamani , Andrés Pérez-López , Osamah Al Walid , Mohammed Suleiman
{"title":"First case of invasive Rasamsonia argillacea in a child with chronic granulomatous disease in Qatar","authors":"Nada Shurab , Anju Sharma , Eman Al Maslamani , Andrés Pérez-López , Osamah Al Walid , Mohammed Suleiman","doi":"10.1016/j.mmcr.2024.100675","DOIUrl":"10.1016/j.mmcr.2024.100675","url":null,"abstract":"<div><div>Invasive fungal infections (IFI) are a major cause of mortality and morbidity in patients with chronic granulomatous disease (CGD). We report and comment on a case of IFI caused by <em>Rasamsonia argillacea</em> in a 16-year-old female with CGD. Additionally, we briefly review and discuss the most challenging aspects of the identification and treatment of this species.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100675"},"PeriodicalIF":1.6,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of flexor tenosynovitis caused by Cyberlindnera rhodanensis – First reported human infection","authors":"Sarah Kim, Stephanie Spivack","doi":"10.1016/j.mmcr.2024.100673","DOIUrl":"10.1016/j.mmcr.2024.100673","url":null,"abstract":"<div><div>We report a case of an immunocompetent individual who was diagnosed with fungal tenosynovitis of the wrist caused by <em>Cyberlindnera rhodanensis</em>, a yeast in the Saccharomycetales order that has never been reported to cause infections in humans. The yeast grew in routine culture and was sent to a reference laboratory for identification and susceptibility testing. The patient ultimately received six surgeries and five months of antifungal therapy, including micafungin and voriconazole, before clinical resolution.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100673"},"PeriodicalIF":1.6,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qi-Hao Yao , Xiu-Jiao Xia , Hui-Lin Zhi , Ze-Hu Liu
{"title":"Extensive erythematous plaques of fungal origin in an overseas student: Cutaneous manifestation of coccidioidomycosis","authors":"Qi-Hao Yao , Xiu-Jiao Xia , Hui-Lin Zhi , Ze-Hu Liu","doi":"10.1016/j.mmcr.2024.100674","DOIUrl":"10.1016/j.mmcr.2024.100674","url":null,"abstract":"<div><div>We present a case of <em>Coccidioides posadasii</em> infection which was contracted during study abroad. This coccidioidomycosis showed atypical manifestations and was diagnosed by a combination of tissue biopsy, metagenomic next–generation sequencing, internal transcribed spacer sequencing and culture. Initial treatment with fluconazole was not effective. Antifungal therapy was switched to voriconazole based on drug sensitivity results with good result. This case demonstrates the clinical significance of combining multiple diagnostic methods.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100674"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Invasive fungal otitis media with peripheral facial paralysis","authors":"Wenjie Kang , Jie Zhang , Hanbing Gao , Ming Guan","doi":"10.1016/j.mmcr.2024.100672","DOIUrl":"10.1016/j.mmcr.2024.100672","url":null,"abstract":"<div><div>Invasive fungal otitis media is clinically rare and diagnosis often delayed. We report a 65-year-old female with <em>Aspergillus fumigatus</em> otitis media complicated by mastoiditis and peripheral facial paralysis. Complete mastoidectomy and type II tympanoplasty, with oral administration of voriconazole for more than 3 months resulted in a successful outcome.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100672"},"PeriodicalIF":1.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osteoarticular mucormycosis of the distal femur in a post COVID-19 patient","authors":"Srinivas Kasha , Venugopal Palakurthi , Ranjith Kumar Yalamanchili , Patil Pratik Yashavant , Rohith GPRK","doi":"10.1016/j.mmcr.2024.100670","DOIUrl":"10.1016/j.mmcr.2024.100670","url":null,"abstract":"<div><div>A 38 year old man with no known comorbidities presented with pain and swelling over the knee joint a few days after recovery from severe COVID-19. Initial debridement and cultures revealed growth of Mucorales affecting a large segment of the distal femur with also positive cultures obtained from the maxillary sinus and the lower lobe of the right lung. Due to this involvement of a long segment of the femur, right lung and left maxillary sinus, a multidisciplinary approach of above knee amputation along with debridement of left maxillary sinus and lobectomy of right lung lower lobe was performed to decrease the fungal load and favour good prognosis. This report warrants the need for early imaging and surgical debridement of tissue for fungal cultures and biopsy in immunocompromised individuals.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100670"},"PeriodicalIF":1.6,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oscar E. Gallardo-Huizar , Joyce Lee , Kailyn Kim , Arthur C. Jeng
{"title":"Miliary coccidioidomycosis mimicking tuberculosis: Case report and review of literature","authors":"Oscar E. Gallardo-Huizar , Joyce Lee , Kailyn Kim , Arthur C. Jeng","doi":"10.1016/j.mmcr.2024.100668","DOIUrl":"10.1016/j.mmcr.2024.100668","url":null,"abstract":"<div><p>Miliary coccidioidomycosis is a severe manifestation of diseases caused by <em>Coccidioides immitis</em> and <em>Coccidioides posadasii</em> that is endemic to the southwestern United States as well as Central and South America. While most cases of coccidioidomycosis present with pulmonary disease, certain risk factors increase the risk for disseminated disease. We present a case of miliary coccidioidomycosis in a 46-year-old patient with uncontrolled diabetes. Additionally, we review the features of thirty-seven cases of patients with miliary coccidioidomycosis.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100668"},"PeriodicalIF":1.6,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000423/pdfft?md5=156b3f4699098efba953fdf89dab80a2&pid=1-s2.0-S2211753924000423-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of refractory onychomycosis caused by Kloeckera apiculata: Successful treatment with itraconazole","authors":"Samantha S. Ehrlich-Fein , Samir B. Patel","doi":"10.1016/j.mmcr.2024.100669","DOIUrl":"10.1016/j.mmcr.2024.100669","url":null,"abstract":"<div><p>Here, we present the case of an otherwise healthy patient, without risk factors, who developed a refractory case of onychomycosis caused by <em>Kloeckera apiculata</em>, an uncommon human pathogen. The diagnosis was ultimately confirmed by fungal nail plate culture, histopathology, and PCR. Whereas prior treatments with topical 5 % tavaborole solution, oral terbinafine, and oral fluconazole were ineffective, complete clinical and mycological cure was achieved with a 3-month course of oral itraconazole.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100669"},"PeriodicalIF":1.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000435/pdfft?md5=0420fe6354c800177ac310de5cbcd22a&pid=1-s2.0-S2211753924000435-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sporotrichosis caused by Sporotrix globosa in an elderly male farmer at the site of a cat scratch","authors":"Yuka Sakai , Yuta Norimatsu , Taro Akatsuka , Toshihisa Hamada , Harumi Gomi , Makoto Sugaya","doi":"10.1016/j.mmcr.2024.100667","DOIUrl":"10.1016/j.mmcr.2024.100667","url":null,"abstract":"<div><p>We report a case of sporotrichosis in an elderly male farmer at the site of a cat scratch scar.</p><p>An 84-year-old Japanese farmer was scratched by his cat two months before his visit to our hospital.</p><p>A skin biopsy was performed. Tissue culture revealed the presence of <em>Sporothrix globosa</em>.</p><p>The patient was treated with oral itraconazole 200 mg/day for 13 months due to a slow healing ulceration, and the symptoms resolved. (71 words).</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100667"},"PeriodicalIF":1.6,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000411/pdfft?md5=d314790347c88ee336a5c6284d3c7f80&pid=1-s2.0-S2211753924000411-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142163235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Teatini Ribeiro , Rachel Basques Caligiorne , Aldrin Pedroza Martins , Antônio Pereira Gomes Neto , Paulo Pereira Christo
{"title":"Meningeal sporotrichosis in an immunocompetent host: A case report","authors":"Victor Teatini Ribeiro , Rachel Basques Caligiorne , Aldrin Pedroza Martins , Antônio Pereira Gomes Neto , Paulo Pereira Christo","doi":"10.1016/j.mmcr.2024.100665","DOIUrl":"10.1016/j.mmcr.2024.100665","url":null,"abstract":"<div><p>A 78-year-old woman presented to hospital with altered mental status. Hyponatremia was diagnosed and treated. She maintained mental confusion despite normal sodium. No headache, fever or focal signs were present. CSF analysis showed chronic meningitis; MRI demonstrated basilar enhancement. She was empirically treated for tuberculosis, with no improvement. PCR for <em>Sporothrix</em> in the CSF was positive. After treatment with Amphotericin followed by oral itraconazole, she completely recovered her cognitive abilities. Follow-up CSF was normal. This report illustrates the need to consider sporotrichosis in the differential diagnosis of chronic meningitis in immunocompetent, and the importance of PCR as a diagnostic tool.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"45 ","pages":"Article 100665"},"PeriodicalIF":1.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753924000393/pdfft?md5=87f779cac484c1888ea96b8fe682203e&pid=1-s2.0-S2211753924000393-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Winnie Kibone , Felix Bongomin , David W. Denning , David B. Meya
{"title":"Primary treatment of chronic pulmonary aspergillosis with weekly liposomal amphotericin B: A case report from Uganda","authors":"Winnie Kibone , Felix Bongomin , David W. Denning , David B. Meya","doi":"10.1016/j.mmcr.2024.100666","DOIUrl":"10.1016/j.mmcr.2024.100666","url":null,"abstract":"<div><p>Chronic pulmonary aspergillosis (CPA) treatment in Africa remains unexplored. We present a 23-year-old Ugandan male, previously treated thrice for pulmonary tuberculosis, developing CPA. Imaging showed lung fibrosis, bronchiectasis, and a fungal ball. He received weekly 600mg (10mg/kg) of liposomal amphotericin B for six weeks, leading to marked clinical improvement. Weekly liposomal amphotericin B may be a viable treatment option for CPA in resource-limited settings.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100666"},"PeriodicalIF":1.6,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221175392400040X/pdfft?md5=869eeb1f4620398c42e0bdd62fda606c&pid=1-s2.0-S221175392400040X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}