Shuyan Quan , Hong Li , Kailing Li , Xuan Wang , Yang Xu , Peng Gu
{"title":"贫血孕妇严重口咽念珠菌病1例报告","authors":"Shuyan Quan , Hong Li , Kailing Li , Xuan Wang , Yang Xu , Peng Gu","doi":"10.1016/j.mmcr.2025.100694","DOIUrl":null,"url":null,"abstract":"<div><div>Hormonal fluctuations during pregnancy increase susceptibility to <em>Candida</em> infections, typically presenting as vulvovaginal candidiasis, but rarely as oropharyngeal candidiasis. We report a rare case of a woman being pregnant for 27 + 1 weeks with twins with oropharyngeal candidiasis, likely attributed to nutritional anemia and adverse reactions of amoxicillin. Following a thorough literature review and evaluation of medication safety during pregnancy regarding route, dosage, and gestational stage, we treated the patient with fluconazole and piperacillin-tazobactam. The patient fully recovered and successfully delivered two infants via cesarean section at term, with no adverse reactions noted during a six-month follow-up.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100694"},"PeriodicalIF":1.6000,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Severe oropharyngeal candidiasis in an anemic pregnant woman: A case report\",\"authors\":\"Shuyan Quan , Hong Li , Kailing Li , Xuan Wang , Yang Xu , Peng Gu\",\"doi\":\"10.1016/j.mmcr.2025.100694\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Hormonal fluctuations during pregnancy increase susceptibility to <em>Candida</em> infections, typically presenting as vulvovaginal candidiasis, but rarely as oropharyngeal candidiasis. We report a rare case of a woman being pregnant for 27 + 1 weeks with twins with oropharyngeal candidiasis, likely attributed to nutritional anemia and adverse reactions of amoxicillin. Following a thorough literature review and evaluation of medication safety during pregnancy regarding route, dosage, and gestational stage, we treated the patient with fluconazole and piperacillin-tazobactam. The patient fully recovered and successfully delivered two infants via cesarean section at term, with no adverse reactions noted during a six-month follow-up.</div></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"47 \",\"pages\":\"Article 100694\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-01-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S221175392500003X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S221175392500003X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Severe oropharyngeal candidiasis in an anemic pregnant woman: A case report
Hormonal fluctuations during pregnancy increase susceptibility to Candida infections, typically presenting as vulvovaginal candidiasis, but rarely as oropharyngeal candidiasis. We report a rare case of a woman being pregnant for 27 + 1 weeks with twins with oropharyngeal candidiasis, likely attributed to nutritional anemia and adverse reactions of amoxicillin. Following a thorough literature review and evaluation of medication safety during pregnancy regarding route, dosage, and gestational stage, we treated the patient with fluconazole and piperacillin-tazobactam. The patient fully recovered and successfully delivered two infants via cesarean section at term, with no adverse reactions noted during a six-month follow-up.