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Severe oropharyngeal candidiasis in an anemic pregnant woman: A case report
IF 1.6
Medical Mycology Case Reports Pub Date : 2025-01-22 DOI: 10.1016/j.mmcr.2025.100694
Shuyan Quan , Hong Li , Kailing Li , Xuan Wang , Yang Xu , Peng Gu
{"title":"Severe oropharyngeal candidiasis in an anemic pregnant woman: A case report","authors":"Shuyan Quan ,&nbsp;Hong Li ,&nbsp;Kailing Li ,&nbsp;Xuan Wang ,&nbsp;Yang Xu ,&nbsp;Peng Gu","doi":"10.1016/j.mmcr.2025.100694","DOIUrl":"10.1016/j.mmcr.2025.100694","url":null,"abstract":"<div><div>Hormonal fluctuations during pregnancy increase susceptibility to <em>Candida</em> infections, typically presenting as vulvovaginal candidiasis, but rarely as oropharyngeal candidiasis. We report a rare case of a woman being pregnant for 27 + 1 weeks with twins with oropharyngeal candidiasis, likely attributed to nutritional anemia and adverse reactions of amoxicillin. Following a thorough literature review and evaluation of medication safety during pregnancy regarding route, dosage, and gestational stage, we treated the patient with fluconazole and piperacillin-tazobactam. The patient fully recovered and successfully delivered two infants via cesarean section at term, with no adverse reactions noted during a six-month follow-up.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100694"},"PeriodicalIF":1.6,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report of childhood onychomycosis caused by the rare yeast Kodamaea ohmeri
IF 1.6
Medical Mycology Case Reports Pub Date : 2025-01-20 DOI: 10.1016/j.mmcr.2025.100695
Thi Minh Chau Ngo , Dong Duong Ton That , Phuong Anh Ton Nu , Le Chi Cao , My Nguyen Thi Tra , Thi Quynh Trang Tran
{"title":"A case report of childhood onychomycosis caused by the rare yeast Kodamaea ohmeri","authors":"Thi Minh Chau Ngo ,&nbsp;Dong Duong Ton That ,&nbsp;Phuong Anh Ton Nu ,&nbsp;Le Chi Cao ,&nbsp;My Nguyen Thi Tra ,&nbsp;Thi Quynh Trang Tran","doi":"10.1016/j.mmcr.2025.100695","DOIUrl":"10.1016/j.mmcr.2025.100695","url":null,"abstract":"<div><div>Onychomycosis is an uncommon disease in pediatric patients with dermatophytes and <em>Candida</em> spp. being the main causative agents. <em>Kodamaea ohmeri</em> has recently emerged as a human pathogen, including an onychomycosis causative agent. Here, we report the first case of childhood onychomycosis caused by <em>K. ohmeri</em> in Vietnam, presenting clinically as a white superficial onychomycosis. Fungal identification was confirmed by sequencing of the ITS1-2 region. Antifungal susceptibility testing revealed low minimum inhibitory concentrations for all tested agents, except fluconazole and caspofungin. The patient was treated with 2 % ketoconazole cream one month, resulting in complete resolution of the nail damage with no relapse observed after six months.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100695"},"PeriodicalIF":1.6,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal mucormycosis by Mucor indicus: A report of two cases
IF 1.6
Medical Mycology Case Reports Pub Date : 2025-01-20 DOI: 10.1016/j.mmcr.2025.100693
Alex Rivero , Megan Shaughnessy , Jessica Oswald , Nicholas Goodhope , Margret Oethinger
{"title":"Gastrointestinal mucormycosis by Mucor indicus: A report of two cases","authors":"Alex Rivero ,&nbsp;Megan Shaughnessy ,&nbsp;Jessica Oswald ,&nbsp;Nicholas Goodhope ,&nbsp;Margret Oethinger","doi":"10.1016/j.mmcr.2025.100693","DOIUrl":"10.1016/j.mmcr.2025.100693","url":null,"abstract":"<div><div>Mucormycosis is an invasive infection caused by fungi of the order Mucorales, typically affecting immunocompromised individuals, and rarely involving the gastrointestinal tract. We report two cases of gastrointestinal mucormycosis by <em>Mucor indicus:</em> a 77-year-old woman with a gastric ulcer and a 25-year-old man with liver lesions. Both were treated with surgery and liposomal amphotericin B; only one survived. Recognizing gastrointestinal mucormycosis in the correct clinical context is essential and requires timely surgical and antifungal treatment.</div><div>2012 Elsevier Ltd. All rights reserved.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100693"},"PeriodicalIF":1.6,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated Scytalidium philadelphianum infection in a Belgian Malinois
IF 1.6
Medical Mycology Case Reports Pub Date : 2025-01-11 DOI: 10.1016/j.mmcr.2025.100692
J.D. Ringhofer , E.M. HIrsch , S.R. Michalak , N. Wiederhold , C. Cañete-Gibas , J.D. Dear
{"title":"Disseminated Scytalidium philadelphianum infection in a Belgian Malinois","authors":"J.D. Ringhofer ,&nbsp;E.M. HIrsch ,&nbsp;S.R. Michalak ,&nbsp;N. Wiederhold ,&nbsp;C. Cañete-Gibas ,&nbsp;J.D. Dear","doi":"10.1016/j.mmcr.2025.100692","DOIUrl":"10.1016/j.mmcr.2025.100692","url":null,"abstract":"<div><div>We report disseminated mycosis in a Belgian Malinois caused by <em>Scytalidium philadelphianum</em>. The dog presented for progressive hindlimb weakness after diagnosis of suspected bacterial discospondylitis. Magnetic resonance imaging combined with radiographs revealed multifocal discospondylitis, osteomyelitis, and spondylitis with epidural empyema. <em>Scytalidium philadelphianum</em> was identified on culture and DNA sequencing of urine and fine needle aspirates of affected disc spaces. Aggressive therapy including amphotericin B liposomal complex, micafungin, and azoles were initiated, but the dog was euthanized seven months later due to progressive neurologic disease. This is the first report of disseminated disease by <em>Scytalidium philadelphianum</em> in veterinary medicine.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100692"},"PeriodicalIF":1.6,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of kerion celsi caused by Trichophyton tonsurans with dermatophytid reaction mimicking a drug eruption and endothrix infection confirmed in pathological tissue 病理组织证实1例由疣状毛癣引起的角质细胞，伴有类似药疹的皮肤癣反应和粘膜感染。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-12-25 DOI: 10.1016/j.mmcr.2024.100691
Makoto Ishiai, Hiroshi Tanabe
{"title":"A case of kerion celsi caused by Trichophyton tonsurans with dermatophytid reaction mimicking a drug eruption and endothrix infection confirmed in pathological tissue","authors":"Makoto Ishiai,&nbsp;Hiroshi Tanabe","doi":"10.1016/j.mmcr.2024.100691","DOIUrl":"10.1016/j.mmcr.2024.100691","url":null,"abstract":"<div><div>We report a case of kerion celsi caused by <em>Trichophyton tonsurans</em> in a teenage male judo athlete, presenting with a lesion in the occipital region. Following the initiation of systemic antifungal therapy, the patient developed a dermatophytid reaction, necessitating differentiation from a drug eruption. Direct microscopy of the affected area confirmed the presence of fungal elements, and histopathological examination revealed endothrix invasion, supporting the continuation of treatment. A drug-induced lymphocyte stimulation test for terbinafine, conducted post-treatment, was negative. This case highlights the importance of distinguishing dermatophytid reactions from drug eruptions to ensure uninterrupted antifungal therapy.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100691"},"PeriodicalIF":1.6,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary coccidioidomycosis presenting as a fungal ball mimicking aspergilloma 肺球孢子菌病表现为真菌球，类似曲菌瘤。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-12-12 DOI: 10.1016/j.mmcr.2024.100690
Rik van den Biggelaar , Tristan Couwenbergh , Alexander C.A.P. Leenders , C.A. van der Sloot , Henrich van der Lee , Jochem B. Buil
{"title":"Pulmonary coccidioidomycosis presenting as a fungal ball mimicking aspergilloma","authors":"Rik van den Biggelaar ,&nbsp;Tristan Couwenbergh ,&nbsp;Alexander C.A.P. Leenders ,&nbsp;C.A. van der Sloot ,&nbsp;Henrich van der Lee ,&nbsp;Jochem B. Buil","doi":"10.1016/j.mmcr.2024.100690","DOIUrl":"10.1016/j.mmcr.2024.100690","url":null,"abstract":"<div><div>A 49-year old female, known to have had an asymptomatic pulmonary cavity since 2015, presented in 2023 with hemoptysis. Radiology showed a mass suspected to be an aspergilloma. Due to persistent hemoptysis, lobectomy was performed. Pathological examination revealed fungal hyphae, and the cultured fungus was identified as a Coccidioides species by LSU sequencing. Microscopy, culture, and ITS sequencing at the national reference center confirmed the identification of Coccidioides posadasii. The patient's last visit to an endemic region was 13 years before the symptomatic disease.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100690"},"PeriodicalIF":1.6,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11713474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fungal keratitis complicating the diagnosis of Acanthamoeba keratitis 真菌性角膜炎并发棘阿米巴角膜炎的诊断。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-12-07 DOI: 10.1016/j.mmcr.2024.100687
Mehrnaz Atighehchian , Alireza Latifi , Zohreh Nozarian , Fahimeh Asadi Amoli , Mehran Zarei-Ghanavati
{"title":"Fungal keratitis complicating the diagnosis of Acanthamoeba keratitis","authors":"Mehrnaz Atighehchian ,&nbsp;Alireza Latifi ,&nbsp;Zohreh Nozarian ,&nbsp;Fahimeh Asadi Amoli ,&nbsp;Mehran Zarei-Ghanavati","doi":"10.1016/j.mmcr.2024.100687","DOIUrl":"10.1016/j.mmcr.2024.100687","url":null,"abstract":"<div><div>A 42-year-old woman was referred to an emergency department. She had an unresponsive corneal ulcer that was initially diagnosed as <em>Herpes simplex</em> virus keratitis. Later, the microbiological studies revealed fungal keratitis. Although the patient was given topical antifungal medication, the clinical presentation did not support improvement. Despite using antifungal medication, the infiltration continued to progress, and the patient underwent therapeutic penetrating keratoplasty (T-PKP). Corneal tissue was collected and sent for histopathologic and molecular examination. The results revealed the presence of both <em>Acanthamoeba</em> T4 subgroup and <em>Fusarium</em> sp. This case emphasizes the importance of considering <em>Acanthamoeba</em> infection in progressive and non-responsive infectious keratitis, especially fungal specimens. Polymerase chain reaction (PCR) is an appropriate laboratory molecular diagnostic test for accurate diagnosis <em>of Acanthamoeba</em> keratitis.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100687"},"PeriodicalIF":1.6,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncommon concurrent pulmonary infections: Aspergillus fumigatus and Lomentospora prolificans in an Anti-MDA5 antibody-positive dermatomyositis patient 罕见并发肺部感染：抗mda5抗体阳性皮肌炎患者的烟曲霉和增生性绵孢菌。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-12-05 DOI: 10.1016/j.mmcr.2024.100689
Maaya Fukumura , Ryosuke Hiwa , Satomi Yukawa , Yasuhiro Tsuchido , Hajime Yoshifuji , Akio Morinobu
{"title":"Uncommon concurrent pulmonary infections: Aspergillus fumigatus and Lomentospora prolificans in an Anti-MDA5 antibody-positive dermatomyositis patient","authors":"Maaya Fukumura ,&nbsp;Ryosuke Hiwa ,&nbsp;Satomi Yukawa ,&nbsp;Yasuhiro Tsuchido ,&nbsp;Hajime Yoshifuji ,&nbsp;Akio Morinobu","doi":"10.1016/j.mmcr.2024.100689","DOIUrl":"10.1016/j.mmcr.2024.100689","url":null,"abstract":"<div><div>A 59-year-old female with anti-MDA5 antibody-positive dermatomyositis was treated with prednisolone, tacrolimus, cyclophosphamide, tofacitinib, and plasma exchange. Five months post-treatment, elevated β-D-glucan levels and a pulmonary shadow on CT were noted. <em>Aspergillus fumigatus</em> was identified, leading to voriconazole initiation. A new pulmonary cavity lesion later revealed <em>Lomentospora prolificans</em>. Considering voriconazole resistance, terbinafine was added, resulting in clinical improvement. Vigilant infection monitoring is crucial during anti-MDA5 antibody-positive dermatomyositis treatment.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"47 ","pages":"Article 100689"},"PeriodicalIF":1.6,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mucormycosis after liver transplant: Case series and literature review 肝移植后的粘孢子菌病：病例系列和文献综述。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.mmcr.2024.100686
Brenda Aceves-Sánchez , Estefano Rojas-Castañeda , Alfredo Ponce-de-León , Álvaro López- Iñiguez , Andrea Rangel-Cordero , Emilio Sánchez , Noel Salgado-Nesme , María F. González-Lara
{"title":"Mucormycosis after liver transplant: Case series and literature review","authors":"Brenda Aceves-Sánchez ,&nbsp;Estefano Rojas-Castañeda ,&nbsp;Alfredo Ponce-de-León ,&nbsp;Álvaro López- Iñiguez ,&nbsp;Andrea Rangel-Cordero ,&nbsp;Emilio Sánchez ,&nbsp;Noel Salgado-Nesme ,&nbsp;María F. González-Lara","doi":"10.1016/j.mmcr.2024.100686","DOIUrl":"10.1016/j.mmcr.2024.100686","url":null,"abstract":"<div><div>We describe two cases of possible healthcare-associated mucormycosis in liver transplant recipients. Mucorales may be acquired from environmental sources such as contaminated medical equipment, grafts or procedure related. Gastrointestinal mucormycosis is the second most common presentation in healthcare-associated infections.</div><div>The high mortality rate of mucormycosis is due to low suspicion, insensitive diagnostic tests and rapid angioinvasion. Early antifungal treatment and surgical debridement are imperative to improve survival.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100686"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractory fungal infection: Three case reports highlighting good practice 难治性真菌感染：三个案例报告强调良好做法。
IF 1.6
Medical Mycology Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.mmcr.2024.100688
Rosemary Barnes , David A. Enoch , Wendy Ingram , Jessica Martin , Jennifer Clay , Netta Tyler , P Lewis White
{"title":"Refractory fungal infection: Three case reports highlighting good practice","authors":"Rosemary Barnes ,&nbsp;David A. Enoch ,&nbsp;Wendy Ingram ,&nbsp;Jessica Martin ,&nbsp;Jennifer Clay ,&nbsp;Netta Tyler ,&nbsp;P Lewis White","doi":"10.1016/j.mmcr.2024.100688","DOIUrl":"10.1016/j.mmcr.2024.100688","url":null,"abstract":"<div><div>Refractory invasive fungal disease is a significant clinical problem, with high morbidity, mortality and costs. The complex causes of refractory infection include breakthrough infection due to antifungal resistance (both innate and acquired), suboptimal therapy and impaired immune responses in critically ill or immunocompromised patients. This case series details three reports on the identification and management of refractory fungal infections, two cases of azole resistance and one case of resistant candidiasis, highlighting the importance of accurate diagnosis, monitoring, implementation of biomarkers (serological markers, PCR), antifungal susceptibility testing and antifungal stewardship to optimise management and minimise risks of emergence of drug resistance.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100688"},"PeriodicalIF":1.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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