Joseph David Cooper, Dennis W. Adams, Lucy Studemeister, Allyson E. Sorensen, Christopher Hull
{"title":"Cutaneous mucormycosis in a patient with Hailey-Hailey disease (benign familial pemphigus) - first reported case","authors":"Joseph David Cooper, Dennis W. Adams, Lucy Studemeister, Allyson E. Sorensen, Christopher Hull","doi":"10.1016/j.mmcr.2026.100819","DOIUrl":"10.1016/j.mmcr.2026.100819","url":null,"abstract":"<div><div>This report describes a case of primary cutaneous mucormycosis in a patient with Hailey-Hailey Disease (benign familial pemphigus). The diagnosis of primary cutaneous mucormycosis was confirmed via microbiological culture as well as histopathology. Our patient improved with prompt surgical debridement and excision of infected, necrotic tissue with complementary antifungal therapy. To the best of our knowledge this is the first reported case of cutaneous mucormycosis in a patient with Hailey-Hailey Disease and contributes to the literature regarding pathophysiology, management and treatment for each of these rare entities.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"53 ","pages":"Article 100819"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148934793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First case report of onychomycosis caused by Exophiala alcalophila","authors":"Lili Rueda-Jaime, Leticia Sopó-Prada, Carolina Firacative","doi":"10.1016/j.mmcr.2026.100820","DOIUrl":"10.1016/j.mmcr.2026.100820","url":null,"abstract":"<div><div>A 46-year-old woman from Colombia, without any medical comorbidities, presented with marked yellowish discoloration of both big toenails, suggestive of onychomycosis, and malalignment of the nail plate. Culture of nail scrapings grew dark-pigmented, mucoid, yeast-like colonies identified as <em>Exophiala alcalophila</em> by ITS sequencing. Broth microdilution identified the isolate as resistant to fluconazole and the echinocandins. The patient refused antifungal treatment. This case highlights the importance of black yeast-like fungi as etiological agents of onychomycosis.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"53 ","pages":"Article 100820"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148934792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atypical cutaneous candidiasis mimicking tinea corporis in an otherwise healthy young man: A case report","authors":"Sibo Liu , Yinggai Song , Aiping Wang","doi":"10.1016/j.mmcr.2026.100800","DOIUrl":"10.1016/j.mmcr.2026.100800","url":null,"abstract":"<div><div>Cutaneous candidiasis typically affects intertriginous areas and may be overlooked when occurring at non-intertriginous sites. We report a 28-year-old otherwise healthy man with a 7-month history of pruritic scaly erythematous lesions on both upper extremities and the upper abdomen. Before presentation, he had used a topical corticosteroid unsupervised for 2 months. The lesions were initially treated as tinea corporis. Direct microscopy showed pseudohyphae and spores, and two consecutive fungal cultures yielded <em>Candida spp.</em>, with CHROMagar <em>Candida</em> supporting <em>Candida albicans</em>. The lesions resolved completely within 2 weeks after oral itraconazole and topical ciclopirox olamine. This case highlights the importance of mycological confirmation in chronic scaly eruptions with unusual distribution, especially in the setting of prior topical corticosteroid exposure.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100800"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah dos Santos Miguel , Erika Yuki Mogami Bomfim , Tiago Pasian Fagundes Santos , Camila Orge Rodrigues , Pedro da Silva Campana , Flávio Guinsburg Hamburger
{"title":"Multisystemic paracoccidioidomycosis with rare retinal and central nervous system involvement: a case report","authors":"Sarah dos Santos Miguel , Erika Yuki Mogami Bomfim , Tiago Pasian Fagundes Santos , Camila Orge Rodrigues , Pedro da Silva Campana , Flávio Guinsburg Hamburger","doi":"10.1016/j.mmcr.2026.100799","DOIUrl":"10.1016/j.mmcr.2026.100799","url":null,"abstract":"<div><div>We report a rare case of disseminated paracoccidioidomycosis in an immunocompetent 41-year-old woman presenting with granulomatous skin lesions, neurological involvement, and subretinal fibrosis leading to exudative retinal detachment and permanent vision loss. Diagnosis was confirmed by direct microscopy, histopathology, and serology. The patient was treated with liposomal amphotericin B followed by trimethoprim-sulfamethoxazole, showing significant clinical improvement. This case highlights an atypical presentation of paracoccidioidomycosis with ocular and central nervous system involvement, emphasizing the need to consider the disease in differential diagnoses even in unusual forms, especially in endemic regions.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100799"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelly Moreira Campos , Frederico de Sottomaior Drumond , Paulo Antônio Ribeiro de Freitas , Raphael Guedes Povoa , Felippe Saad , Marcello Mihailenko Chaves Magri , Wellingson Silva Paiva
{"title":"Disseminated paracoccidioidomycosis with a pulmonary-spine fistula: suggestive of contiguous spread","authors":"Michelly Moreira Campos , Frederico de Sottomaior Drumond , Paulo Antônio Ribeiro de Freitas , Raphael Guedes Povoa , Felippe Saad , Marcello Mihailenko Chaves Magri , Wellingson Silva Paiva","doi":"10.1016/j.mmcr.2026.100801","DOIUrl":"10.1016/j.mmcr.2026.100801","url":null,"abstract":"<div><div>Paracoccidioidomycosis (PCM) rarely involves the spine. We report a 55-year-old man with disseminated PCM presenting with thoracic spinal cord compression and an unprecedented pulmonary-spine fistula identified intraoperatively. Diagnosis was confirmed by histopathology and mycology. The patient underwent surgical decompression and stabilization followed by itraconazole, achieving complete neurological recovery. This case highlights a unique complication of PCM and supports combined surgical and antifungal management in cases with neurological compromise.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100801"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Late-onset Exophiala dermatitidis keratitis after cataract surgery: A case report and literature review","authors":"Atsuhiko Fukuto , Suzu Deie , Yosuke Inada , Takashi Yaguchi , Hirokazu Sakaguchi , Taiichiro Chikama","doi":"10.1016/j.mmcr.2026.100805","DOIUrl":"10.1016/j.mmcr.2026.100805","url":null,"abstract":"<div><div>We report <em>Exophiala dermatitidis</em> keratitis developing one year following cataract surgery in a 73-year-old immunocompetent man. Before the correct diagnosis was established, the patient was initially treated for suspected epithelial ingrowth with corticosteroids for ten months. Therapeutic penetrating keratoplasty was required, despite intensive antifungal therapy including topical and systemic voriconazole and amphotericin B. This case underscores the criticality of considering fungal infection in atypical postoperative presentations with prolonged corticosteroid exposure.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100805"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shan Kai Ing , Yih Hoong Lee , Yuet Yang Tan , Munirah Binti Abdul Aziz , Andrew Kean Wei Chang
{"title":"Primary traumatic cutaneous aspergillosis of the hand caused by Aspergillus terreus following a mould-contaminated penetrating injury","authors":"Shan Kai Ing , Yih Hoong Lee , Yuet Yang Tan , Munirah Binti Abdul Aziz , Andrew Kean Wei Chang","doi":"10.1016/j.mmcr.2026.100798","DOIUrl":"10.1016/j.mmcr.2026.100798","url":null,"abstract":"<div><div>A 39-year-old man with poorly controlled diabetes mellitus developed progressive hand infection after a mould-contaminated penetrating steel injury. Operative debridement revealed sloughy infected tissue, and cultures from pus, tissue, and slough all yielded <em>Aspergillus terreus</em>. There was no evidence of disseminated infection. He improved with surgical source control, voriconazole therapy, and optimisation of glycaemic control. This case highlights traumatic inoculation as an important mechanism of primary cutaneous aspergillosis and the importance of early fungal-directed therapy.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100798"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Cappozzo , Teresa Battaglia , Marta Nebiolo , Marcello Mariani , Virginia Livellara , Gabriele Gaggero , Elena Arkangelskaya , Maria Beatrice Damasio , Lorenzo Anfigeno , Camilla De Luca , Stefano Avanzini , Federico Palo , Massimo Conte , Elio Castagnola
{"title":"Corrigendum to “Redefining ultrasound's role in early diagnosis of hepatosplenic candidiasis during neutropenia: A pediatric case report in solid tumor” [Med. Mycol. Case Rep., 51 (2026) 100777]","authors":"Francesca Cappozzo , Teresa Battaglia , Marta Nebiolo , Marcello Mariani , Virginia Livellara , Gabriele Gaggero , Elena Arkangelskaya , Maria Beatrice Damasio , Lorenzo Anfigeno , Camilla De Luca , Stefano Avanzini , Federico Palo , Massimo Conte , Elio Castagnola","doi":"10.1016/j.mmcr.2026.100788","DOIUrl":"10.1016/j.mmcr.2026.100788","url":null,"abstract":"","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100788"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148231037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Cappiello , Matthew Carlin Corpuz Bonus , Sandy Chang , Jonathan Arcobello
{"title":"Disseminated Verruconis gallopava in a kidney transplant recipient on belatacept, who failed isavuconazole and improved on dual amphotericin B and posaconazole therapy","authors":"Matthew Cappiello , Matthew Carlin Corpuz Bonus , Sandy Chang , Jonathan Arcobello","doi":"10.1016/j.mmcr.2026.100802","DOIUrl":"10.1016/j.mmcr.2026.100802","url":null,"abstract":"<div><div>Disseminated phaeohyphomycosis can have severe consequences in immunocompromised hosts, and does not have standardized therapeutic protocols. A 68-year-old man with prior renal transplant presented with nodular pneumonia. Symptoms worsened despite empiric antimicrobials, including isavuconazole for antifungal coverage. After new T2-enhancing lesions were seen on MRI brain along with worsened pulmonary and soft tissue lesions, transbronchial biopsy revealed disseminated <em>Verruconis gallopava</em> as the inciting pathogen. Therapy was successfully narrowed to posaconazole based on sensitivities. Future literature should evaluate the most optimal first-line therapy for <em>Verruconis</em>, due to the high morbidity and mortality seen in disseminated disease.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100802"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148231318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disseminated histoplasmosis evading detection in an immunocompromised patient","authors":"Queen Pierre , Dalal Chenouda","doi":"10.1016/j.mmcr.2026.100804","DOIUrl":"10.1016/j.mmcr.2026.100804","url":null,"abstract":"<div><div><em>Histoplasma capsulatum</em> is a pathogenic fungus known to exist across the world, especially in the Ohio and Mississippi River Valleys. While clinicians commonly rely on urine and serum <em>Histoplasma</em> antigen testing for rapid detection of disseminated Histoplasmosis, these diagnostic tests have limitations. We present a case of a patient who initially had negative urine and serum <em>Histoplasma</em> antigen tests and required additional testing with lymph node biopsy and immunodiffusion to establish a diagnosis of histoplasmosis. This case highlights the importance of employing multiple testing methods when there is strong clinical suspicion for Histoplasmosis.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"52 ","pages":"Article 100804"},"PeriodicalIF":1.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148184518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}