Severe oropharyngeal candidiasis in an anemic pregnant woman: A case report

Abstract

Hormonal fluctuations during pregnancy increase susceptibility to Candida infections, typically presenting as vulvovaginal candidiasis, but rarely as oropharyngeal candidiasis. We report a rare case of a woman being pregnant for 27 + 1 weeks with twins with oropharyngeal candidiasis, likely attributed to nutritional anemia and adverse reactions of amoxicillin. Following a thorough literature review and evaluation of medication safety during pregnancy regarding route, dosage, and gestational stage, we treated the patient with fluconazole and piperacillin-tazobactam. The patient fully recovered and successfully delivered two infants via cesarean section at term, with no adverse reactions noted during a six-month follow-up.