罕见酵母菌引起儿童甲真菌病1例报告

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Medical Mycology Case Reports Pub Date : 2025-01-20 DOI:10.1016/j.mmcr.2025.100695

Thi Minh Chau Ngo , Dong Duong Ton That , Phuong Anh Ton Nu , Le Chi Cao , My Nguyen Thi Tra , Thi Quynh Trang Tran

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引用次数: 0

摘要

小儿甲真菌病是一种罕见的疾病，以皮肤真菌和念珠菌为主要病原体。最近出现了一种人类病原体，包括一种甲癣病原体。在这里，我们报告第一例儿童甲真菌病引起的K. ohmeri在越南，临床表现为白色浅表性甲真菌病。通过对ITS1-2区域的测序证实了真菌的鉴定。抗真菌药敏试验显示，除氟康唑和卡泊芬净外，所有试验药物的最低抑菌浓度均较低。患者用2%酮康唑乳膏治疗1个月，甲损伤完全消退，6个月后无复发。

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A case report of childhood onychomycosis caused by the rare yeast Kodamaea ohmeri

Onychomycosis is an uncommon disease in pediatric patients with dermatophytes and Candida spp. being the main causative agents. Kodamaea ohmeri has recently emerged as a human pathogen, including an onychomycosis causative agent. Here, we report the first case of childhood onychomycosis caused by K. ohmeri in Vietnam, presenting clinically as a white superficial onychomycosis. Fungal identification was confirmed by sequencing of the ITS1-2 region. Antifungal susceptibility testing revealed low minimum inhibitory concentrations for all tested agents, except fluconazole and caspofungin. The patient was treated with 2 % ketoconazole cream one month, resulting in complete resolution of the nail damage with no relapse observed after six months.

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来源期刊

Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

47 days