Imaging Science in Dentistry最新文献

{"title":"Reliability of a novel stent-based tomographic method to measure dimensional changes after alveolar ridge preservation in extraction sockets with buccal bone dehiscence.","authors":"Malena Aguilar Porta, María Pía Burelli, Matías Urdapilleta, Mariel Gómez, Daniel Gustavo Olmedo","doi":"10.5624/isd.20250208","DOIUrl":"https://doi.org/10.5624/isd.20250208","url":null,"abstract":"<p><strong>Purpose: </strong>This study presents and evaluates the reliability of a novel standardized tomographic measurement method using a digitally designed stent to assess dimensional changes after alveolar ridge preservation in extraction sockets with buccal bone dehiscence.</p><p><strong>Materials and methods: </strong>Nine patients requiring extraction of a single-rooted tooth with 2-8 mm buccal bone dehiscence were included. A tomographic guide was digitally designed to fit the adjacent teeth and included a hyperdense element to identify the exact site of the bone defect. The guide was used during the initial pre-extraction scan to localize the defect. Six months after extraction and alveolar ridge preservation, and before implant placement, a second scan was performed with the same guide. Two calibrated examiners identified the corresponding slices from the pre- and post-extraction scans by locating the hyperdense marker. They digitally superimposed the images and performed measurements to evaluate changes in ridge dimensions. Each examiner repeated the measurements 3 times, 1 week apart. Intra- and inter-examiner reliability was assessed using intraclass correlation coefficients.</p><p><strong>Results: </strong>The intra-examiner intraclass correlation coefficients for dimensional changes ranged from 0.71 to 0.99. The inter-examiner coefficients were 0.94 for buccal bone height, 0.76 for palatal bone height, 0.87 for buccal ridge width, and 0.79 for palatal ridge width, although wide confidence intervals suggested some variability between examiners.</p><p><strong>Conclusion: </strong>The proposed method enabled precise identification of the same anatomical site across scans. It provided a repeatable, reproducible approach for standardized measurement of alveolar ridge changes following preservation procedures in sockets with buccal bone dehiscence.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"45-53"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective evaluation of mandibular third molars using simulated low-dose cone-beam computed tomography: A comparative image quality study.","authors":"Dalia Homar Asan, Josefine Cederhag, Xie-Qi Shi, Mats Nilsson, Kristina Hellén-Halme","doi":"10.5624/isd.20250212","DOIUrl":"https://doi.org/10.5624/isd.20250212","url":null,"abstract":"<p><strong>Purpose: </strong>This study was performed to establish a procedure for simulated low-dose cone-beam computed tomography (CBCT) scans and to investigate whether the resulting images are comparable in diagnostic accuracy to those obtained using a clinical low-dose protocol.</p><p><strong>Materials and methods: </strong>ImageJ was used to manipulate the sinogram data from CBCT scans acquired at 5 mA to mimic a technical setting of 2 mA by adding noise to the Radon-transformed projection data before image reconstruction. Four observers compared the simulated 2 mA CBCT scans with original clinical 2 mA CBCT scans acquired previously. The CBCT images were analysed using a protocol with a ranking scale, and the observers were required to select only 1 category for each variable. The Wilcoxon signed-rank test was used to assess differences between the 2 CBCT scan types, with a significance level of <i>P</i><0.05. Intra-observer agreement was evaluated using the Cohen kappa.</p><p><strong>Results: </strong>Pairwise observer comparisons of the simulated and clinical low-dose CBCT scans showed no significant differences in image quality. Intra-observer agreement was acceptable, and in 5 comparisons, the results indicated a high degree of agreement.</p><p><strong>Conclusion: </strong>Simulated low-dose CBCT scans can be generated using ImageJ. No significant differences in image quality were observed between simulated and clinical low-dose CBCT scans when evaluating mandibular third molars. These findings suggest that manipulation of sinogram data is a promising radiation-free approach for simulating low-dose images in optimisation efforts.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"54-61"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Side- and patient-based performance of a deep learning system based on the results of individual detection of carotid artery calcifications on panoramic radiographs.","authors":"Yuta Mitsuya, Chiaki Kuwada, Sujin Yang, Yoshitaka Kise, Mizuho Mori, Yukiko Takashi, Masako Nishiyama, Natsuho Ishikawa, Munetaka Naitoh, Eiichiro Ariji","doi":"10.5624/isd.20250232","DOIUrl":"https://doi.org/10.5624/isd.20250232","url":null,"abstract":"<p><strong>Purpose: </strong>The present study aimed to develop 2 deep learning (DL) systems incorporating detection functions for the diagnosis of carotid artery calcifications (CACs) on panoramic radiographs and to compare their diagnostic performances using CAC-based, side-based, and patient-based evaluations.</p><p><strong>Materials and methods: </strong>Panoramic radiographs from 290 patients with CACs and 290 control patients without CACs were used to develop 2 detection models: one designed to detect individual CACs across the entire radiograph (System 1) and another designed to detect CACs within the limited bilateral cervical areas (System 2). CAC-based performance was evaluated using recall, precision, and F1-score. Side-based and patient-based performances were assessed using sensitivity, specificity, positive predictive value, negative predictive value, accuracy, and the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>For System 1, CAC-based recall, precision, and F1-score were 0.81, 0.68, and 0.74, respectively. For System 2, the corresponding values were 0.90, 0.67, and 0.77. Side-based sensitivity, specificity, and AUC were 0.87, 0.80, and 0.83 for System 1, and 0.93, 0.84, and 0.89 for System 2. Patient-based sensitivity, specificity, and AUC were 0.93, 0.73, and 0.83 for System 1, and 0.95, 0.70, and 0.83 for System 2. Although a relatively large number of false positives were observed in CAC-based assessments, side-based and patient-based performances showed improvement.</p><p><strong>Conclusion: </strong>Side-based and patient-based performances were sufficient when calculated on the basis of CAC-based evaluations for diagnosing CACs on panoramic radiographs. When conducting studies of this type, performance assessments should include side-based and patient-based evaluations in addition to CAC-based analyses.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"83-92"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual monoenergetic imaging for metal artifact reduction in dental implant surgery using photon-counting detector computed tomography.","authors":"Adib Al-Haj Husain, Victor Mergen, Thomas Sartoretti, Nadin Al-Haj Husain, Sebastian Winklhofer, Hatem Alkadhi, Bernd Stadlinger, Harald Essig, Silvio Valdec","doi":"10.5624/isd.20250216","DOIUrl":"https://doi.org/10.5624/isd.20250216","url":null,"abstract":"<p><strong>Purpose: </strong>This <i>ex vivo</i> study was performed to determine the optimal energy level for virtual monoenergetic images (VMIs) generated with photon-counting detector computed tomography (PCD-CT) to minimize metal artifacts from dental implants.</p><p><strong>Materials and methods: </strong>Twelve implants from various manufacturers were placed in 6 pig mandibles and scanned with PCD-CT. VMIs were reconstructed at energy levels from 70 keV to 150 keV in 20-keV increments. Three readers with varying experience qualitatively assessed the image quality, artifact burden, and diagnostic interpretability of peri-implant soft and hard tissues using a 5-point discrete visual scale. Objective analyses included quantitative line profile analysis of implant-induced artifacts. Descriptive statistics were calculated, and inter-reader agreement was assessed using percentage agreement and the Krippendorff alpha coefficient.</p><p><strong>Results: </strong>Qualitative analysis demonstrated excellent image quality for VMIs at ≥110 keV (median=5), with minimal artifacts observed at 130-150 keV. In contrast, lower-energy VMIs (70-90 keV) showed inferior performance due to artifact-related limitations in diagnostic interpretability. Inter-reader agreement ranged from moderate to perfect, with perfect reliability (α=1) for VMIs ≥110 keV. Quantitative line-profile analysis confirmed reduced artifact burden at higher energy levels, particularly for VMIs ≥110 keV.</p><p><strong>Conclusion: </strong>VMI at energy levels ≥110 keV on PCD-CT reduced dental implant-related metal artifacts and offered excellent image quality, including assessment of both peri-implant soft and hard tissues. These findings suggest that optimized PCD-CT VMI may enhance postoperative follow-up imaging. Future <i>in vivo</i> studies are warranted to validate these findings in clinical practice.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"62-72"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and assessment of an <i>ex vivo</i> imaging protocol for dental-dedicated MRI systems: A pilot study.","authors":"Gabriela Salatino Liedke, Jennifer Christensen, Lucas Machado Maracci, Brian Hansen, Rubens Spin-Neto","doi":"10.5624/isd.20250228","DOIUrl":"https://doi.org/10.5624/isd.20250228","url":null,"abstract":"<p><strong>Purpose: </strong>This study proposes an <i>ex vivo</i> imaging protocol using a dental-dedicated magnetic resonance imaging (ddMRI) system and qualitatively and quantitatively evaluates the effects of phosphate-buffered saline (PBS) washing on image quality.</p><p><strong>Materials and methods: </strong>Four half-maxillae and 4 half-mandibles from human cadaveric donors were scanned using a ddMRI system with a dental-specific coil. Two pulse sequences (\"anatomy\" and \"inflammation\") were applied. Each specimen was imaged at 4 time points: immediately after PBS immersion and after 24, 48, and 72 hours of washing, totaling 64 images. Image quality was evaluated using signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and conspicuity of anatomical structures: cortical bone, medullary bone, root contour, soft tissue, and the sinus floor/mandibular canal. Conspicuity was rated by 3 observers and analyzed using the Cochran Q test (α=0.05).</p><p><strong>Results: </strong>Cortical bone, medullary bone, and the sinus floor were depicted in all images; root contours (91.1%) and soft tissue (85.9%) were visible in most images. PBS washing did not significantly impact conspicuity (<i>P</i>>0.05). Signal intensity was higher in \"anatomy\" than \"inflammation.\" In the \"anatomy\" sequence, both SNR and CNR initially declined, then stabilized from 24 hours onward. CNR between medullary bone and soft tissue showed the greatest improvement with extended PBS washing, especially for the \"inflammation\" sequence.</p><p><strong>Conclusion: </strong>The proposed ddMRI protocol enabled consistent visualization of dentomaxillofacial structures in <i>ex vivo</i> samples. PBS represented a suitable carrier. Although PBS washing did not influence conspicuity, at least 24 hours of washing may improve image quality, as reflected by SNR and CNR.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"73-82"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of dental-dedicated magnetic resonance imaging for 2-dimensional orthodontic diagnosis: A pilot study of landmark identification.","authors":"Sukeshana Srivastav, Peter B Stoustrup, Jason Liu, Maria Isabella Federici, Jennifer Christensen, Rubens Spin-Neto","doi":"10.5624/isd.20250201","DOIUrl":"https://doi.org/10.5624/isd.20250201","url":null,"abstract":"<p><strong>Purpose: </strong>Lateral cephalograms are conventionally used for landmark identification and cephalometric analysis, but expose patients to ionizing radiation. Magnetic resonance imaging (MRI) is increasingly employed to evaluate various tissue types, with dental-dedicated MRI (ddMRI) emerging as a promising modality in clinical dentistry. High-quality MRI could offer a radiation-free alternative for orthodontic diagnosis and treatment planning. This pilot study aimed to evaluate the reliability of ddMRI for 2-dimensional (2D) orthodontic cephalometric landmark identification and annotation.</p><p><strong>Materials and methods: </strong>Thirteen volunteers (7 men, 6 women; mean age 33±5.2 years) underwent ddMRI. Three independent raters identified 2D cephalometric landmarks and annotated their positions on the same ddMRI datasets twice. The 3D Slicer application was used to identify key orthodontic cephalometric landmarks on multiplanar reconstruction images in the sagittal plane. Intra-rater and inter-rater reproducibility were assessed using intraclass correlation coefficients (ICCs), and reliability was evaluated by nominal differences in linear distance (mm) between annotated points.</p><p><strong>Results: </strong>Intra-rater ICCs ranged from 0.909 to 0.999, and inter-rater ICCs ranged from 0.988 to 0.999, indicating excellent intra- and inter-rater reliability. Bland-Altman plots were used to display mean differences (mm) and limits of agreement (±1.96 standard deviations) between annotations to assess potential biases.</p><p><strong>Conclusion: </strong>ddMRI is a feasible imaging modality for 2D orthodontic landmark identification. Based on intra- and inter-rater reproducibility values, ddMRI demonstrates high reliability in identifying key orthodontic cephalometric landmarks, providing a radiation-free alternative for orthodontic diagnosis and treatment planning.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"36-44"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"YOLOv8m-segmentation for detecting cervical burnout and caries in bitewing radiographs: A deep learning approach.","authors":"Mohd Isyrafuddin Bin Ismail, Nooritawati Md Tahir, Wan Syahirah Binti W Samsudin, Mas Suryalis Ahmad, Nashuha Omar, Mohd Yusmiaidil Putera Mohd Yusof","doi":"10.5624/isd.20250194","DOIUrl":"https://doi.org/10.5624/isd.20250194","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the performance of the YOLOv8m-seg model in detecting and delineating interproximal caries and cervical burnout on bitewing radiographs and examined whether increasing the number of training epochs improved segmentation accuracy and consistency.</p><p><strong>Materials and methods: </strong>In total, 1,410 bitewing radiographs were annotated using polygon-based masks by a trained dental clinician. The YOLOv8m-seg model was trained for 50, 100, and 150 epochs on 1,128 images and validated on 282 images using the Ultralytics segmentation framework. Model performance was assessed using precision, recall, and mean average precision at intersection-over-union thresholds of 0.5 and 0.5 to 0.95 (mAP0.5, mAP0.5-0.95) for both bounding box and mask outputs. Additional evaluation was conducted on a non-augmented validation subset.</p><p><strong>Results: </strong>Extended training duration was associated with improved segmentation performance. The highest mask mAP0.5-0.95 value was 0.828 at epoch 150. Both box-based precision and recall increased with longer training, whereas mask-based evaluation more accurately reflected the model's ability to delineate the boundaries of caries and cervical burnout. Performance appeared consistent across both classes in the augmented validation split but was reduced in the non-augmented validation subset.</p><p><strong>Conclusion: </strong>The YOLOv8m-seg model demonstrated high diagnostic accuracy in distinguishing proximal caries from cervical burnout on bitewing radiographs. Its mask-based outputs may assist clinicians in early lesion recognition and support improved diagnostic decision-making. Future studies should evaluate model generalizability across broader populations and diverse clinical environments and should prioritize assessment using non-augmented validation sets and independent test datasets.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"26-35"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological analysis of anatomical structure of nasopharynx in cone-beam computed tomography in Korean population.","authors":"Chena Lee, Ji Yun Lee, David MacDonald","doi":"10.5624/isd.20250264","DOIUrl":"https://doi.org/10.5624/isd.20250264","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the nasopharyngeal anatomy, particularly the fossa of Rosenmüller (FoR), on cone-beam computed tomography (CBCT) in a Korean population to establish normative reference data by sex and age.</p><p><strong>Materials and methods: </strong>In CBCT images, FoR was classified into three types (A-C) for image analysis. Measurements of nasopharyngeal dimensions were performed in Types B and C. Sex- and age-related differences were evaluated using chi-square and independent t-tests, and reliability was assessed using the intraclass correlation coefficient.</p><p><strong>Results: </strong>In total, 492 CBCTs (244 males, 248 females; 20-69 years) were included. Type C was the most frequent morphology and increased with age. Types A and B were more prevalent among males than among females, whereas Type C was predominant among females (57.3%) compared with males (34.4%). Asymmetry was more frequent in males (13.9%) than in females (10.1%). Significant sex differences due to the larger males were found in the distance of the torus levatorius, the distance between the sphenopalatine notch and the right torus levatorius, and the horizontal and vertical dimensions of the FoR. No significant side-to-side differences were observed. Reliability was excellent (ICC=0.97).</p><p><strong>Conclusion: </strong>Type C was the most frequent morphology in both sexes, whereas Types A and B were more frequently observed in males than in females. These differences may indirectly contribute to sex-related disparities in nasopharyngeal carcinoma (NPC) incidence. The normative reference values may aid early detection in dental imaging, and further prospective studies including NPC patients are needed to clarify the role of nasopharyngeal morphology.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"93-99"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-density areas within low-density areas in radiographs of dentigerous cysts.","authors":"Takashi Eda, Chinami Igarashi","doi":"10.5624/isd.20250156","DOIUrl":"https://doi.org/10.5624/isd.20250156","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to analyze radiographs of dentigerous cysts containing high-density areas within low-density areas to identify their characteristic radiographic features.</p><p><strong>Materials and methods: </strong>This retrospective study included histopathologically confirmed cases of dentigerous cysts in patients who underwent computed tomography (CT). The analyses included demographic data, the position of the low-density area relative to the impacted tooth, and the number, size, and location of the high-density area within the low-density region. Group comparisons were performed for each analytical factor.</p><p><strong>Results: </strong>The patients were classified into 550 cases of dentigerous cysts without high-density areas and 34 cases with high-density areas within the low-density regions. In the group with high-density areas, the low-density regions more frequently extended beyond the cementoenamel junction toward the center of the tooth root. In addition, many lesions exhibited high-density areas with a maximum diameter of less than 3 mm, contact with the tooth crown, and involvement of impacted teeth.</p><p><strong>Conclusion: </strong>Lesions displaying high-density features, such as a maximum diameter <3 mm, contact with the tooth crown, and association with impacted teeth, are likely dentigerous cysts. These findings suggest that dentigerous cysts containing high-density areas differ from other lesions with calcified components. Although such cases are rare, recognizing them is important for understanding the disease spectrum.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"20-25"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected delayed orofacial symptoms induced by facial cosmetic filler: A report of 3 cases.","authors":"Hyewon Seo, Gyu-Dong Jo, Yoon Joo Choi, Kug Jin Jeon, Sang-Sun Han, Chena Lee","doi":"10.5624/isd.20250144","DOIUrl":"https://doi.org/10.5624/isd.20250144","url":null,"abstract":"<p><p>In addition to well-known side effects such as rash, redness, and bone resorption, unexpected facial complications may occasionally occur several years after certain medical procedures. This report presents rare cases of orofacial symptoms that developed as delayed responses to cosmetic filler injections. Three separate patients presented to the authors' institution with varying severities of orofacial symptoms. These symptoms, initially diagnosed clinically as inflammation or neoplasms of the parotid gland, were later identified through magnetic resonance imaging as diseases potentially associated with filler materials injected approximately 4-8 years earlier. The primary goal of this report was to inform specialists in the oral and maxillofacial field about the possibility of such complications, enabling them to manage patient symptoms effectively and develop appropriate treatment strategies.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"56 1","pages":"100-105"},"PeriodicalIF":2.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}