Journal of Obstetrics and Gynecology of India最新文献

{"title":"Revolutionary Approaches to Sperm Selection: Enhancing Male Fertility Through Advanced Processing Techniques.","authors":"Rajajeyakumar Manivel, A S Vickram, Nidhi Sharma, Sargunadevi Sivanantham","doi":"10.1007/s13224-025-02136-2","DOIUrl":"https://doi.org/10.1007/s13224-025-02136-2","url":null,"abstract":"<p><strong>Background: </strong>Male infertility, often worsened by oxidative stress, remains a challenging issue that significantly impacts sperm quality.</p><p><strong>Objectives: </strong>Reactive oxygen species (ROS) are key contributors to sperm DNA damage, reduced motility, and abnormal morphology. In response to these challenges, advanced sperm processing techniques like density gradient centrifugation and magnetic-activated sperm cell sorting have been developed to optimize sperm selection and reduce ROS levels.</p><p><strong>Conclusion: </strong>This commentary examines recent research on these techniques and their impact on sperm quality, highlighting their potential in the treatment of male infertility.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"176-178"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Levels of Placental Growth Factor and Soluble FMS-Like Tyrosine Kinase with Severity and Prognosis of Preeclampsia-Eclampsia Syndrome.","authors":"Shubhi Bandlish, Reeti Mehra, Poonam Goel, Jasbinder Kaur, Seema Gupta","doi":"10.1007/s13224-025-02170-0","DOIUrl":"https://doi.org/10.1007/s13224-025-02170-0","url":null,"abstract":"<p><strong>Background: </strong>Preeclampsia is a multifactorial disorder of hypertension in pregnancy which contributes majorly to maternal and perinatal morbidity and mortality. PLGF (placental growth factor) and sFlt-1(soluble fms-like tyrosine kinase) are measurable biomolecules which can be used as biomarkers. This study estimated the levels of PLGF and sFlt-1 in patients of preeclampsia<b>-</b>eclampsia syndrome and correlated them with disease severity and prognosis.</p><p><strong>Methods: </strong>A longitudinal observational study was conducted enrolling 125 women with preeclampsia<b>-</b>eclampsia syndrome and levels of PLGF, sFlt-1 and their ratio were correlated with disease severity and prognosis.</p><p><strong>Results: </strong>The levels of serum biomarkers in the patients of preeclampsia were compared with patients of preeclampsia with severe features and eclampsia and no significant correlation was found. The patients with preeclampsia had a median value of sFlt-1 and ratio sFlt-1/PLGF as 24.50 ng/ml, and 13.50, respectively, whereas patients in the severe group had a median value of sFlt-1 as 28.00 ng/ml and ratio sFlt-1/PLGF as 14.00, respectively (<i>p</i> values 0.340 and 0.815, respectively). Patients with preeclampsia had PLGF in range of 938-13,317 pg/ml versus 1192.50-2708.75 pg/ml in those with severe disease (<i>p</i> value 0.610).</p><p><strong>Conclusion: </strong>Although serum sFlt-1 was higher, serum PLGF was lower and the ratio of sFlt-1/PLGF was higher in patients with severe preeclampsia in comparison with non-severe cases, the difference was not statistically significant.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"125-131"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unintended Consequences: Vaginal Calculus Formation Around a Long-Term Copper IUD.","authors":"Juhi Deshpande","doi":"10.1007/s13224-025-02243-0","DOIUrl":"https://doi.org/10.1007/s13224-025-02243-0","url":null,"abstract":"<p><p>A 60-year-old obese woman presented with severe vaginal pain and a large mass. Manual extraction revealed a copper IUD embedded in a 40 g calculus. This rare case highlights the importance of regular gynecologic care for all women, prompt IUD removal, and proper management to prevent complications.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"169-171"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Periodontal Health.","authors":"Neha Mishra, Ashok Kumar","doi":"10.1007/s13224-025-02344-w","DOIUrl":"https://doi.org/10.1007/s13224-025-02344-w","url":null,"abstract":"<p><strong>Background: </strong>Periodontal disease is a highly prevalent inflammatory condition that tends to worsen during pregnancy due to hormonal, vascular, and immune changes. Emerging data suggests that poor maternal periodontal health may influence pregnancy outcomes, yet it often remains overlooked and uncared in routine antenatal care.</p><p><strong>Objectives: </strong>This review was written to summarize the global and Indian burden of periodontal disease in pregnancy, explain its biological mechanisms, and evaluate its association with adverse perinatal outcomes, along with available preventive and treatment strategies.</p><p><strong>Methods: </strong>A targeted search of PubMed, Google Scholar, and Embase (2015 onwards) was conducted. Of 206 articles screened, 44 met eligibility criteria and were included. Studies describing epidemiology, pathophysiology, diagnostic features, maternal-foetal effects, and treatment outcomes were reviewed. Select earlier studies were added for diagnostic and therapeutic clarity.</p><p><strong>Results: </strong>Globally, pregnancy-related gingivitis affects majority of women, with periodontitis prevalence varying widely across regions, including India. Periodontal inflammation may elevate systemic cytokines and bacterial endotoxins, contributing to preeclampsia, gestational diabetes, preterm birth, low birth weight, and foetal growth restriction. Non-surgical periodontal therapy in the second trimester is safe and may modestly reduce preterm birth and low birth weight, though findings vary across studies.</p><p><strong>Conclusion: </strong>Maternal periodontal disease is a modifiable risk factor with important implications for pregnancy outcomes. Integrating oral health screening, counselling, and timely periodontal care into antenatal services could support healthier maternal and neonatal outcomes. Further well-designed trials are needed to define the magnitude of benefit from treatment.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"97-103"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study Between the Diagnostic Accuracy of IOTA Simple Rules and Risk Malignanct Index (RMI) in Differentiating Malignant from Benign Adnexal Masses.","authors":"Venkateswaran Nandhana, K S Raja Rajeswari, Karthik Sadhana","doi":"10.1007/s13224-025-02185-7","DOIUrl":"https://doi.org/10.1007/s13224-025-02185-7","url":null,"abstract":"<p><strong>Background: </strong>Of all the gynecologic cancers, ovarian cancer has the greatest clinical challenge. It is often asymptomatic at an earlier stage and many of them present in an advanced stage for which the five-year survival rate remains low. However, the major hurdle faced by gynecologists is in diagnosing the disease early, owing to the fact that ovarian malignancies do not manifest clinically until a later stage.</p><p><strong>Purpose of the study: </strong>As the most important prognostic factor is the quality of primary cytoreductive surgery, a high degree of suspicion and multi-diagnostic approach is required in patients with nonspecific symptoms in the high-risk age group, to detect the malignancy at its earliest. There are only few studies on classification systems to categorize ovarian mass into benign and malignant pre-operatively and to decide upon proper management and counseling of the patient.</p><p><strong>Methodology: </strong>In this study we assessed \"the accuracy of International Ovarian Tumor Analysis (IOTA) simple rules with Risk Malignancy Index (RMI) to differentiate benign from malignant adnexal mass\". By evaluating the performance of each classification system, we analyzed the nature of an adnexal mass pre-operatively based on its score and hence decide upon the treatment modality. A total of 49 patients were enrolled in the study and were followed up by menopausal status, ultrasonogram and serum tumour markers.</p><p><strong>Results: </strong>When compared to HPE, RMI had sensitivity of 71.43% (95% CI 29.04-96.33%), Specificity was 97.62% (95% CI 87.43-99.94%), False positive rate was 2.38% (95% CI 0.06-12.57%), False negative rate was 28.57% (95% CI 3.67-70.96%), Positive predictive value was 83.33% (95% CI 35.88-99.58%), Negative predictive value was 95.35% (95% CI 84.19-99.43%) and Diagnostic accuracy was 93.88% (95% CI 83.13-98.72%) When compared to HPE, IOTA had a sensitivity of 100.00% (95% CI 2.50-100.00%), Specificity of 94.59% (95% CI 81.81-99.34%), False positive rate of 5.41% (95% CI 0.66-18.19%), False negative rate of 0.00% (95% CI - to 97.50%), Positive predictive value of 33.33% (95% CI 0.84-90.57%), Negative predictive value of 100.00% (95% CI 90.00-100.00%), and the Diagnostic accuracy was 94.74% (95% CI 82.25-99.36%).</p><p><strong>Conclusion: </strong>The diagnostic accuracy of the IOTA is better than RMI in our cohort study, which is synchronous. Though the diagnostic accuracy of RMI is found to be fairly good in our study population, it has misdiagnosed 4% of patients as benign when HPE was suggestive of Malignancy which majorly questions its role as a tool for pre-operative evaluation. Subjective assessment by an experienced sonographer combined with the use of serum tumour markers currently seems to be the most effective method to preoperatively characterize ovarian tumors.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"118-124"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Pregnancy and Childbirth Decades After Renal Transplant.","authors":"Vinni Anna Jacob, Sandhra Jiby, Georgi Abraham, Milly Mathew","doi":"10.1007/s13224-025-02143-3","DOIUrl":"https://doi.org/10.1007/s13224-025-02143-3","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"165-168"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Applebaum Uterine Scoring System with Pregnancy Outcomes among Infertile Patients Undergoing Embryo Transfer in a Tertiary Care Hospital.","authors":"Anshikha Arora, Shipra Gupta","doi":"10.1007/s13224-025-02198-2","DOIUrl":"https://doi.org/10.1007/s13224-025-02198-2","url":null,"abstract":"<p><strong>Introduction: </strong>Embryo transfer is the most crucial and final step in IVF cycle, accounting for about 30% failures in case of improper technique. Therefore, a new concept of evaluating uterine receptivity by M. Applebaum was developed that has shown promising results to predict IVF outcome.</p><p><strong>Aim and objectives: </strong>To evaluate uterine receptivity by using Applebaum scoring system and correlate the parameters with pregnancy outcomes among infertile patients undergoing embryo transfer in a tertiary care hospital in North India.</p><p><strong>Material and methods: </strong>This was a prospective interventional study, conducted in Department of Obstetrics and Gynecology at SRMSIMS, Bareilly on 60 patients who presented with infertility during the period from July 2023 to September 2023. To assess uterine receptivity, ultrasonographic and Doppler parameters were analyzed and scored as per parameters of Applebaum uterine scoring system and serum beta-human chorionic gonadotropin was performed 14 days after ET to confirm the pregnancy.</p><p><strong>Observations: </strong>The mean age and BMI among the females who conceived was 34.78 ± 6.28 years and 23.7 ± 2.17 kg/m2respectively, majority of whom had marriage duration of 4-6 years. Pulsatility Index, myometrial contraction, and total Applebaum uterine score parameters were significantly (p 0.05) higher among patients with pregnancy than without pregnancy.</p><p><strong>Conclusion: </strong>The endometrial receptivity is predeterminant in predicting the pregnancy outcome. Uterine scoring system will help to perform embryo transfers in only favourable uterine environment.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"108-112"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Laparotomy and Laparoscopy for the Management of Endometrioid Endometrial Cancer with Cervical Involvement.","authors":"Cem Yagmur Ozdemir, Nayif Cicekli, Hüseyin Coşkun, Riza Dur, Ilhan Demir, Necat Çağatay Sezer, Dagistan Tolga Arioz","doi":"10.1007/s13224-025-02216-3","DOIUrl":"https://doi.org/10.1007/s13224-025-02216-3","url":null,"abstract":"<p><strong>Aim: </strong>We aimed to compare overall survival (OS) and progression-free survival (PFS) between patients treated with laparoscopy and laparotomy for endometrioid endometrial cancer (EEC) with cervical involvement.</p><p><strong>Methods: </strong>A total of 41 patients with EEC with cervical involvement were included in the study. The exclusion criteria were non-endometriod type endometrial cancer in the postoperative pathology report results, synchronous tumor or stage I endometrial cancer. Additionally, stage III and stage IV patients without cervical involvement were excluded. Participants were categorized into two groups, namely group 1 (21 patients who underwent laparotomy) and group 2 (20 patients who underwent laparoscopic surgery).</p><p><strong>Results: </strong>5-year OS of EEC with cervical involvement was 61%, 52.4% in group 1 and 70% in group 2 (<i>p</i> = 0.417). Recurrence was detected in 7 patients. 5-year PFS of EEC with cervical involvement was 82.9%, 85.7% in group 1 and 80% in group 2 (<i>p</i> = 0.704). No significant difference was detected in terms of recurrence between the two groups (<i>p</i> = 0.840).</p><p><strong>Conclusion: </strong>EEC represents the most common endometrial cancer subgroup and has a favorable prognosis. In this study, although our patient number was small, we compared laparoscopy and laparotomy in the treatment of EEC with cervical involvement and no statistical difference was found.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"113-117"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Feasibility Study on the Effect of a 12-Week Pelvic Floor and Core Training on Pain, Muscle Strength and Thickness in Women with Chronic Non-specific Low Back Pain.","authors":"Madhavi Thuramalla, Antony Leo Aseer Peter, Krishna Reddy Nallamalla, Sathyaprabha Balasubramanian, Manjula Rao, Suresh Palakamsetti","doi":"10.1007/s13224-025-02237-y","DOIUrl":"https://doi.org/10.1007/s13224-025-02237-y","url":null,"abstract":"<p><strong>Background: </strong>Combining training for the pelvic floor muscle (PFM) with core stability exercises have unique advantages for treating Chronic Non-specific Low back pain (CNSLBP).Given the significant role of PFM in lumbar spine stability and the suggested link between lumbar instability and Low Back Pain in women, it was hypothesized that PFM exercises could provide beneficial outcomes for patients with CNSLBP Objective: To evaluate the effect of a 12 week Pelvic floor muscle and core training program in women with CNSLBP.</p><p><strong>Methods: </strong>A total of 70 women with CNSLBP (20-40 years) participated in the study. They were randomly allocated into 2 groups. Group A received PFM  Exercises combined with Core stabilization  exercises, and Group B received core stabilization exercises alone for 12 successive weeks. Pain intensity, Muscle strength (transverse abdominis (TrA) and pelvic floor muscles (PFM)), and thickness (TrA and PFM) were measured before and after treatment program.</p><p><strong>Statistical analysis: </strong>There was no difference between the groups in terms of age, BMI, number of births and mode of delivery (<i>p</i> > 0.05) and also in all clinical parameters (<i>p</i>  <  0.05)p more than 0.05 between the groups at the baseline. Independent and paired <i>t</i>-tests were used.</p><p><strong>Results: </strong>Post-intervention analysis revealed significant differences between the two groups in pain, strength, and muscle thickness, favouring the interventional group (<i>p</i>  <  0.05).</p><p><strong>Discussion: </strong>The current study assessed the efficacy of the intervention on several key outcomes, including pain, muscle strength (TrA and PFM), and muscle thickness (TrA and PFM). The intervention group demonstrated notable enhancements in pain, muscle strength and thickness, suggesting a positive impact of the intervention on muscular outcomes.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"138-146"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Surgeries in Benign Gynaecological Conditions: Experience in Our Institution.","authors":"N V Manjula, K S Poojashree, Nidhi Umesh","doi":"10.1007/s13224-025-02181-x","DOIUrl":"https://doi.org/10.1007/s13224-025-02181-x","url":null,"abstract":"<p><strong>Background: </strong>Gynaecological robotic surgery is one of the latest transformations in minimally invasive operative techniques. Gynaecological surgeons treat several conditions that affect a woman's reproductive organs using miniature instruments guided through a robotic system. Currently, benign gynaecological surgeries do not have many remarkable advantages over conventional laparoscopic surgeries. EndoWrist manoeuvres of robotic instruments resemble the open surgical technique, which allows better and precise suturing than conventional laparoscopy in procedures like myomectomy and sacrocolpopexies. Our study showcases our adaptation to the newest innovation and its outcome.</p><p><strong>Methodology: </strong>Our prospective study includes 30 benign gynaecological cases operated by single surgeon in Da Vinci Xi system from June 2023 to July 2024. This included 28 hysterectomies and 2 myomectomies. Baseline demographic data, docking time, console time, blood loss, post-operative pain and dosage of analgesia taken, post-op ambulation, length of hospital stay, and post-op complications have been assessed.</p><p><strong>Results: </strong>The BMI of 30-34.9 kg/m² contributed to 24%, and 35-39.9 kg/m² contributed to 21%. Docking time reduced from around 45 ± 15 min to 15 ± 5 min. An average console time was 132 min, which stepped down from 216 min. The average blood loss in 50% of them is 50-100 ml. A 95% of patients were discharged between 3 and 5 days. Post-operatively, 35% had mild pain and 50% moderate pain, assessed by the VAS scale.</p><p><strong>Conclusion: </strong>A minimally invasive technique with outcomes similar to laparoscopy but with an EndoWrist movement aiding to a less steeper learning curve to the surgeons and patient friendly outcomes which enhance with expertise.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"76 2","pages":"104-107"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}